Detailed information for compound 332534

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 349.638 | Formula: C13H17ClIN
  • H donors: 0 H acceptors: 0 LogP: 4.13 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: ICC1CN(C)CCC1c1ccc(cc1)Cl
  • InChi: 1S/C13H17ClIN/c1-16-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13H,6-9H2,1H3
  • InChiKey: OCCOPDTVLJQBPD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References
Rattus norvegicus Norepinephrine transporter Starlite/ChEMBL References
Rattus norvegicus Dopamine transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium vivax amine transporter, putative Norepinephrine transporter   597 aa 483 aa 21.1 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 534 aa 41.0 %
Brugia malayi Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 581 aa 34.6 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 522 aa 22.0 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 595 aa 34.0 %
Onchocerca volvulus Norepinephrine transporter   597 aa 540 aa 46.3 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Norepinephrine transporter   597 aa 551 aa 47.4 %
Onchocerca volvulus Norepinephrine transporter   597 aa 548 aa 24.8 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 508 aa 32.7 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Norepinephrine transporter   597 aa 501 aa 39.7 %
Neospora caninum sodium-dependent transporter, putative Norepinephrine transporter   597 aa 507 aa 30.4 %
Onchocerca volvulus Norepinephrine transporter   597 aa 554 aa 38.6 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 529 aa 41.6 %
Plasmodium yoelii hypothetical protein Norepinephrine transporter   597 aa 478 aa 19.7 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.5 %
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Norepinephrine transporter   597 aa 549 aa 41.9 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Norepinephrine transporter   597 aa 569 aa 24.8 %
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative Norepinephrine transporter   597 aa 579 aa 22.1 %
Loa Loa (eye worm) hypothetical protein Norepinephrine transporter   597 aa 551 aa 25.0 %
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.0 %
Onchocerca volvulus Norepinephrine transporter   597 aa 570 aa 38.6 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Norepinephrine transporter   597 aa 513 aa 38.4 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Norepinephrine transporter   597 aa 545 aa 41.7 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 579 aa 35.1 %
Onchocerca volvulus Transmembrane protein 120 homolog Norepinephrine transporter   597 aa 577 aa 34.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0098 0.0218 0.1641
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0002 0.0007
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0558 0.4245
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0031 0.0201
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0177 0.0412 0.2752
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0078 0.0169 0.0304
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0161 0.0374 0.063
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0012 0.0006 0.0033
Leishmania major histone deacetylase, putative 0.0526 0.1272 0.8498
Loa Loa (eye worm) hypothetical protein 0.007 0.015 0.0994
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0069 0.0913
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0027 0.0005
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0242 0.1612
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0013 0.0007
Plasmodium vivax importin-beta 2, putative 0.0028 0.0046 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0013 0.0013
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0028 0.0028
Echinococcus multilocularis cyclin dependent kinase 5 0.0043 0.0082 0.0136
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni hypothetical protein 0.0261 0.062 0.1858
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0049 0.0324
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0031 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.015 0.0128
Echinococcus multilocularis Immunoglobulin 0.0015 0.0014 0.0021
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0177 0.0412 0.2752
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.034 0.227
Loa Loa (eye worm) hypothetical protein 0.0042 0.0079 0.0522
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0069 0.0063
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0026 0.004
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0066 0.0192
Echinococcus multilocularis protein patched 0.0125 0.0285 0.048
Chlamydia trachomatis protoporphyrinogen oxidase 0.0043 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0176 0.0409 0.273
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0412 0.1235
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0015 0.0013 0.0019
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.008
Plasmodium vivax hypothetical protein, conserved 0.005 0.0098 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Onchocerca volvulus 0.0021 0.0027 0.0308
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0012 0.0006 0.0033
Loa Loa (eye worm) hypothetical protein 0.0176 0.0409 0.273
Trichomonas vaginalis glutaminase, putative 0.0542 0.1311 1
Treponema pallidum DNA ligase (lig) 0.003 0.0049 0.0697
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Echinococcus multilocularis histone deacetylase 1 0.0526 0.1272 0.2152
Loa Loa (eye worm) hypothetical protein 0.025 0.0592 0.3955
Echinococcus granulosus sterol regulatory element binding protein 0.0125 0.0285 0.0849
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0038 0.0069 0.0069
Echinococcus granulosus defective proboscis extension response 0.0015 0.0014 0.0037
Schistosoma mansoni ets 0.001 0.0002 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0015 0.0091
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0646
Brugia malayi hypothetical protein 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Leishmania major hypothetical protein, conserved 0.0016 0.0015 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.0149
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0069 0.0913
Schistosoma mansoni hypothetical protein 0.0047 0.0091 0.0274
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0048 0.0353
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0091 0.0152
Plasmodium falciparum histone deacetylase 1 0.0526 0.1272 0.1267
Echinococcus multilocularis cpg binding protein 0.006 0.0124 0.0207
Brugia malayi BRCA1-associated protein 2 containing protein 0.0012 0.0006 0.0027
Echinococcus multilocularis histone deacetylase 7 0.0617 0.1496 0.2531
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0049 0.0318
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0218 0.0196
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.0282 0.1882
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0169
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0046 0.0271
Echinococcus granulosus histone deacetylase 1 0.0526 0.1272 0.3805
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0701
Plasmodium vivax protein kinase Crk2 0.0043 0.0082 0.0082
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0012 0.0006 0.0033
Brugia malayi Csnk2b protein 0.0038 0.0069 0.0448
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0153 0.0256
Leishmania major DNA polymerase kappa, putative 0.0022 0.0031 0.0169
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0048 0.0378
Toxoplasma gondii patched family protein 0.0018 0.002 0.002
Entamoeba histolytica Ran family GTPase 0.0021 0.0028 0.0219
Echinococcus multilocularis casein kinase ii subunit beta 0.0038 0.0069 0.0113
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0066 0.0198
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0326 0.078 0.5211
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0242 0.1612
Loa Loa (eye worm) oxidoreductase 0.0021 0.0027 0.0175
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0098 0.0294
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.018
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0083 0.0083
Brugia malayi hypothetical protein 0.0018 0.002 0.0121
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0025 0.0025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0066 0.0109
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0008 0.0035
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0072 0.0153 0.1016
Echinococcus multilocularis conserved hypothetical protein 0.0015 0.0013 0.0019
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0094
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0082 0.0179 0.0299
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0014 0.0035
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0093 0.0618
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0049 0.0352
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0002 0.0006
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0047 0.0091 0.0091
Plasmodium falciparum histone deacetylase, putative 0.0617 0.1496 0.1491
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0048 0.0048
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0031 0.0088
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0027 0.0175
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0282 0.0845
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0099 0.016
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0043 0.0083 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0169
Entamoeba histolytica hypothetical protein 0.003 0.0049 0.0388
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0069 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0012 0.0006 0.0006
Brugia malayi nuclear receptor RXR 0.0011 0.0002 0.0003
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0049 0.0148
Echinococcus granulosus serotonin transporter 0.0292 0.0695 0.2078
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0002 0.0007
Mycobacterium ulcerans oxidoreductase 0.0043 0.0083 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0218 0.1451
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0091 0.0268
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0026 0.0077
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0043 0.0082 0.0513
Loa Loa (eye worm) patched family protein 0.0018 0.002 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0268 0.1787
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0027 0.0143
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Chlamydia trachomatis DNA ligase 0.003 0.0049 0.0001
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0043 0.0083 0.0248
Brugia malayi phosphofructokinase 0.0108 0.0242 0.1607
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0106 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0013 0.0013
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.004 0.0258
Brugia malayi RE40412p 0.0015 0.0013 0.0074
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0099 0.0624
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0098 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0242 0.1825
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0014 0.0035
Schistosoma mansoni amine oxidase 0.0043 0.0083 0.0248
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.025 0.0592 0.1769
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0082 0.0179 0.0535
Loa Loa (eye worm) patched family protein 0.0018 0.002 0.0127
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.0215 0.1427
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.015 0.0128
Loa Loa (eye worm) hypothetical protein 0.0125 0.0285 0.1901
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0098 0.0163
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0161 0.0374 0.1114
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0006
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0066 0.0109
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0026 0.0071
Trypanosoma brucei DNA polymerase eta, putative 0.0097 0.0215 0.1404
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0026 0.004
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0038 0.0069 0.0422
Trypanosoma cruzi histone deacetylase 1, putative 0.0526 0.1272 0.8503
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0015 0.0038
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Onchocerca volvulus 0.0031 0.0052 0.0672
Trypanosoma brucei histone deacetylase 1 0.0526 0.1272 0.8498
Echinococcus multilocularis microtubule associated protein 2 0.1365 0.3339 0.5654
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0062 0.0102
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0526 0.1272 0.9703
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.008 0.008
Echinococcus multilocularis histone deacetylase 6 0.0617 0.1496 0.2531
Schistosoma mansoni histone deacetylase 0.0526 0.1272 0.3809
Schistosoma mansoni casein kinase II beta subunit 0.0038 0.0069 0.0206
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0026 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0009
Echinococcus granulosus nibrin 0.003 0.0049 0.0142
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.00000000013362
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0069 0.0541
Loa Loa (eye worm) patched family protein 0.0018 0.002 0.0127
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0043 0.0083 0.0248
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0067
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0022 0.0306
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0292 0.0695 0.2083
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0099 0.0093
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0153 0.1016
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.008 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0082 0.0605
Echinococcus granulosus dna polymerase kappa 0.0098 0.0218 0.0647
Echinococcus granulosus dnaJ subfamily B 0.0808 0.1967 0.5888
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0034
Mycobacterium tuberculosis Conserved hypothetical protein 0.0072 0.0153 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0026 0.0159
Onchocerca volvulus 0.015 0.0346 0.4926
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0228
Echinococcus multilocularis bloom syndrome protein 0.002 0.0025 0.0039
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0242 0.0407
Echinococcus multilocularis nibrin 0.003 0.0049 0.008
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0015 0.0058
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0098 0.0163
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0098 0.0289
Plasmodium falciparum amino acid transporter, putative 0.005 0.0098 0.0092
Echinococcus multilocularis alkaline phosphatase 0.0161 0.0374 0.063
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0091
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0193
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0161 0.0374 0.063
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0352
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.049
Plasmodium falciparum histone deacetylase 2 0.0617 0.1496 0.1491
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0008 0.0035
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0022
Plasmodium vivax histone deacetylase, putative 0.0617 0.1496 0.1496
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0066 0.048
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.004 0.004
Brugia malayi RNA binding protein 0.0124 0.0282 0.1877
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0436
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0275 0.0825
Loa Loa (eye worm) hypothetical protein 0.0154 0.0355 0.2366
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0098 0.0163
Toxoplasma gondii histone deacetylase HDAC2 0.0526 0.1272 0.1272
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0116 0.077
Schistosoma mansoni histone deacetylase hda2 0.0629 0.1525 0.4568
Echinococcus multilocularis 0.0043 0.0083 0.0137
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0261 0.062 0.1858
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.018
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Schistosoma mansoni hypothetical protein 0.0121 0.0274 0.0821
Schistosoma mansoni microtubule-associated protein tau 0.1365 0.3339 1
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0049 0.0324
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0025 0.0068
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0043 0.0083 0.0077
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0049 0.0352
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0025 0.0019
Echinococcus multilocularis dna polymerase kappa 0.0098 0.0218 0.0366
Trichomonas vaginalis ran, putative 0.0021 0.0028 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Schistosoma mansoni terminal deoxycytidyl transferase 0.0072 0.0153 0.0458
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0093 0.0616
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0083 0.0083
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0052 0.0085
Trichomonas vaginalis DNA polymerase eta, putative 0.0098 0.0218 0.1641
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0015 0.0091
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0242 0.1902
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2407 0.5905 1
Brugia malayi RNA, U transporter 1 0.0081 0.0175 0.1162
Brugia malayi steroid hormone receptor 0.002 0.0026 0.0159
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0014
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0015 0.0013 0.0034
Echinococcus granulosus neuroglian 0.0015 0.0014 0.0037
Echinococcus multilocularis histone deacetylase 3 0.0526 0.1272 0.2152
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0043 0.0082 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0026 0.0159
Loa Loa (eye worm) hypothetical protein 0.0097 0.0215 0.1433
Schistosoma mansoni topbp1 0.003 0.0049 0.0148
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0093 0.0279
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0025 0.0019
Schistosoma mansoni hypothetical protein 0.0082 0.0179 0.0535
Loa Loa (eye worm) histone deacetylase 7A 0.0617 0.1496 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Echinococcus granulosus microtubule associated protein 2 0.1365 0.3339 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0098 0.0163
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0026 0.0071
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0093 0.0154
Echinococcus multilocularis cyclin dependent kinase 0.0043 0.0082 0.0136
Leishmania major histone deacetylase, putative 0.0617 0.1496 1
Echinococcus multilocularis protoporphyrinogen oxidase 0.0043 0.0083 0.0137
Brugia malayi protein C24B5.3 0.0018 0.002 0.0121
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0099 0.016
Echinococcus granulosus snurportin 1 0.0304 0.0724 0.2164
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0049 0.0292
Echinococcus granulosus phd:f box containing protein 0.0016 0.0015 0.0038
Brugia malayi histone deacetylase 3 (HD3) 0.0526 0.1272 0.8502
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0003 0.0026
Loa Loa (eye worm) glutaminase 0.0542 0.1311 0.8762
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0078 0.0169 0.1095
Echinococcus multilocularis flap endonuclease 1 0.0026 0.004 0.0064
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0526 0.1272 0.9703
Brugia malayi Histone deacetylase family protein 0.0617 0.1496 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0352
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0049 0.0049
Brugia malayi 6-phosphofructokinase 0.0108 0.0242 0.1607
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0091 0.06
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0571 0.1384 0.2783
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0639
Brugia malayi Muscleblind-like protein 0.0443 0.1068 0.7139
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0352
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0002 0.0009
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0082 0.0179 0.0299
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0013 0.0075
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0027 0.0213
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0015 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0026 0.0159
Echinococcus granulosus alkaline phosphatase 0.0161 0.0374 0.1114
Mycobacterium ulcerans monoamine oxidase 0.0043 0.0083 0.0061
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0098
Brugia malayi MH2 domain containing protein 0.0118 0.0268 0.1782
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Schistosoma mansoni alkaline phosphatase 0.0161 0.0374 0.1119
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0027 0.0014
Brugia malayi RE40412p 0.0015 0.0013 0.0074
Brugia malayi AMP-binding enzyme family protein 0.007 0.015 0.0989
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0015 0.0091
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0082 0.0647
Trypanosoma brucei cdc2-related kinase 1 0.0043 0.0082 0.0513
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0093 0.0273
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0015 0.0038
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0066 0.0404
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0701
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.033 0.099
Brugia malayi Histone deacetylase 1 0.0526 0.1272 0.8502
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0048 0.0042
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Giardia lamblia Replication factor C, subunit 1 0.003 0.0049 0.0363
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0242 0.0439
Schistosoma mansoni hypothetical protein 0.0121 0.0274 0.0821
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Brugia malayi histone deacetylase 11 0.026 0.0616 0.4112
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0226
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0027 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0014 0.0083
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0098 0.0294
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0062 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0026 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0026 0.0071
Onchocerca volvulus 0.0015 0.0013 0.0101
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0026 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0026 0.0159
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0027 0.0027
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0252 0.0252
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0027 0.0027
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.025 0.0592 0.1773
Echinococcus multilocularis Immunoglobulin 0.0015 0.0014 0.0021
Brugia malayi Patched related family protein 10 0.0018 0.002 0.0121
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0099 0.016
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0242 0.0724
Echinococcus granulosus histone deacetylase 8 0.026 0.0616 0.184
Brugia malayi jmjC domain containing protein 0.0016 0.0015 0.0085
Echinococcus granulosus FTZ F1 alpha 0.002 0.0026 0.0071
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0061
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0003 0.0026
Trypanosoma brucei unspecified product 0.0092 0.0202 0.1314
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0072 0.0564
Brugia malayi hypothetical protein 0.003 0.0049 0.0318
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0282 0.0845
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Schistosoma mansoni ran 0.0021 0.0028 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.0303
Schistosoma mansoni coup transcription factor 0.002 0.0026 0.0077
Echinococcus granulosus GPCR family 2 0.0047 0.0091 0.0268
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0066 0.052
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Echinococcus granulosus roundabout 2 0.0015 0.0014 0.0037
Loa Loa (eye worm) histone deacetylase 1 0.0526 0.1272 0.8503
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0177 0.0412 0.2752
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Echinococcus granulosus expressed conserved protein 0.0275 0.0652 0.1949
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0242 0.1902
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0025 0.0164
Schistosoma mansoni DNA polymerase eta 0.0097 0.0215 0.0644
Mycobacterium ulcerans dehydrogenase 0.0043 0.0083 0.0061
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.033 0.0557
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0027 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0013 0.0082
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0023 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0052 0.0157
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0049 0.0388
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0027 0.0169
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0027 0.0014
Brugia malayi ecdysteroid receptor 0.002 0.0026 0.0159
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0015 0.0013 0.0078
Echinococcus multilocularis snurportin 1 0.0304 0.0724 0.1223
Echinococcus granulosus cyclin dependent kinase 1 0.0043 0.0082 0.0241
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0013 0.0076
Echinococcus granulosus histone deacetylase 3 0.0526 0.1272 0.3805
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.008 0.008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0001
Schistosoma mansoni thyroid hormone receptor 0.002 0.0026 0.0077
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0091 0.06
Toxoplasma gondii histone deacetylase HDAC4 0.026 0.0616 0.0616
Echinococcus multilocularis histone deacetylase 0.0617 0.1496 0.2531
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Onchocerca volvulus 0.0018 0.002 0.0203
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.012 0.02
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.015 0.1176
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0072 0.0153 0.0256
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0026 0.0165
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Toxoplasma gondii zinc finger cdgsh type protein 0.0015 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0488 0.3258
Onchocerca volvulus 0.0018 0.002 0.0203
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0048 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0031 0.0201
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0015 0.0038
Trypanosoma brucei unspecified product 0.0049 0.0098 0.0618
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0027 0.0143
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0209 0.0492 0.7073
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0026 0.0159
Toxoplasma gondii histone lysine-specific demethylase 0.0043 0.0083 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0615 0.149 0.1471
Echinococcus multilocularis tumor protein p63 0.0333 0.0797 0.1347
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0022 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Loa Loa (eye worm) hypothetical protein 0.012 0.0271 0.1807
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni sodium/chloride dependent transporter 0.0051 0.0102 0.0305
Plasmodium falciparum importin beta, putative 0.0028 0.0046 0.004
Trichomonas vaginalis BRCA1-associated protein, putative 0.0012 0.0006 0.002
Loa Loa (eye worm) patched family protein 0.0018 0.002 0.0127
Schistosoma mansoni hypothetical protein 0.0176 0.0409 0.1224
Schistosoma mansoni hypothetical protein 0.0808 0.1967 0.589
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0242 0.0719
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0226
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0026 0.0165
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0002 0.0003
Loa Loa (eye worm) serotonin transporter b 0.0292 0.0695 0.4646
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0026 0.0159
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0082 0.0545
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0098 0.0294
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0027 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0083 0.0548
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Toxoplasma gondii patched family protein 0.0018 0.002 0.002
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0015 0.0013 0.0039
Entamoeba histolytica histone deacetylase, putative 0.0526 0.1272 1
Echinococcus granulosus conserved hypothetical protein 0.0015 0.0013 0.0033
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0062 0.0181
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Echinococcus granulosus histone deacetylase 6 0.0617 0.1496 0.4476
Onchocerca volvulus 0.0105 0.0234 0.3315
Brugia malayi hypothetical protein 0.0011 0.0002 0.0003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0098 0.0294
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0082 0.0545
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0352
Schistosoma mansoni histone deacetylase 0.0526 0.1272 0.3809
Entamoeba histolytica deoxycytidyl transferase, putative 0.0072 0.0153 0.1202
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0175
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0072 0.0153 0.0458
Echinococcus granulosus dual specificity 0.0177 0.0412 0.123
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0209 0.0492 0.0446
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi nuclear receptor NHR-88 0.002 0.0026 0.0159
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0242 0.1902
Echinococcus granulosus histone deacetylase 6 0.0629 0.1525 0.4565
Onchocerca volvulus 0.005 0.0098 0.1341
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0006
Brugia malayi cell division control protein 2 homolog 0.0043 0.0082 0.0539
Schistosoma mansoni histone deacetylase 1 2 3 0.026 0.0616 0.1845
Loa Loa (eye worm) hypothetical protein 0.0443 0.1068 0.7141
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0082 0.0623
Echinococcus multilocularis sterol regulatory element binding protein 0.0125 0.0285 0.048
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0027 0.0021
Echinococcus granulosus cpg binding protein 0.006 0.0124 0.0366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0026 0.0165
Echinococcus multilocularis serotonin transporter 0.0292 0.0695 0.1175
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0048 0.0342
Loa Loa (eye worm) apoptosis regulator protein 0.0082 0.0179 0.1189
Schistosoma mansoni ran 0.0021 0.0028 0.0083
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0436
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0043 0.0083 0.0137
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0015 0.0091
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0027 0.0175
Echinococcus multilocularis dual specificity 0.0177 0.0412 0.0695
Plasmodium vivax patched family protein, putative 0.0018 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0169
Schistosoma mansoni hypothetical protein 0.0047 0.0091 0.0274
Loa Loa (eye worm) hypothetical protein 0.0061 0.0127 0.0844
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0069 0.0454
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0026 0.0077
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0177 0.0412 0.2728
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0013 0.0082
Schistosoma mansoni sodium/chloride dependent transporter 0.0292 0.0695 0.2083
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.0013 0.0007
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0297 0.0707 0.2118
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0098 0.0294
Loa Loa (eye worm) hypothetical protein 0.0292 0.0695 0.4646
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0026 0.0077
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0218 0.1423
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0031 0.0031
Brugia malayi jmjC domain containing protein 0.0058 0.012 0.0791
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Onchocerca volvulus 0.0021 0.0027 0.0308
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Loa Loa (eye worm) hypothetical protein 0.015 0.0346 0.2305
Trichomonas vaginalis helicase, putative 0.0013 0.0008 0.0035
Leishmania major histone deacetylase, putative 0.0617 0.1496 1
Onchocerca volvulus Protein patched homolog 0.0018 0.002 0.0203
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0026 0.0159
Loa Loa (eye worm) hypothetical protein 0.0069 0.0146 0.0972
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0033 0.0228
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Loa Loa (eye worm) hypothetical protein 0.0082 0.0179 0.1189
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0006 0.0006
Brugia malayi AMP-binding enzyme family protein 0.007 0.015 0.0989
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0025 0.0068
Brugia malayi jmjC domain containing protein 0.0016 0.0015 0.0085
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0646
Loa Loa (eye worm) hypothetical protein 0.0443 0.1068 0.7141
Trypanosoma cruzi DNA polymerase eta, putative 0.0097 0.0215 0.1433
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0015 0.0013 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0082 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Plasmodium vivax histone deacetylase 1, putative 0.0526 0.1272 0.1272
Leishmania major hypothetical protein, conserved 0.005 0.0099 0.0624
Toxoplasma gondii chorismate synthase, putative 0.407 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0082 0.0136
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0031 0.0169
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0061
Loa Loa (eye worm) hypothetical protein 0.0148 0.034 0.227
Loa Loa (eye worm) RNA binding protein 0.0124 0.0282 0.1882
Trichomonas vaginalis brca1-associated protein, putative 0.0012 0.0006 0.002
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0161 0.0374 0.063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Brugia malayi hypothetical protein 0.005 0.0098 0.0646
Schistosoma mansoni histone deacetylase 4 5 0.0617 0.1496 0.4479
Giardia lamblia Hypothetical protein 0.0015 0.0013 0.0078
Leishmania major histone deacetylase, putative 0.0526 0.1272 0.8498
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0026 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0125 0.0285 0.2156
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0026 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0153 0.1011
Trypanosoma brucei cdc2-related kinase 3 0.0043 0.0082 0.0513
Loa Loa (eye worm) RecQ helicase 0.002 0.0025 0.0159
Brugia malayi TAR-binding protein 0.0124 0.0282 0.1877
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0015 0.0022
Toxoplasma gondii hypothetical protein 0.005 0.0098 0.0098
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0026 0.0165
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0098 0.0294
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0049 0.0043
Brugia malayi Patched related family protein 12 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0091
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0033 0.0215
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0013 0.0013
Schistosoma mansoni DNA ligase IV 0.003 0.0049 0.0148
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0046 0.0271
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.008
Plasmodium vivax amine transporter, putative 0.005 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0159
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0026 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Schistosoma mansoni cpg binding protein 0.006 0.0124 0.0371
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0015 0.0013 0.0039
Schistosoma mansoni 3-dehydroquinate synthase 0.0133 0.0305 0.0913
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0412 0.3123
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0242 0.1612
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0343 0.0821 0.0821
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0093 0.0154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0052 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0009
Toxoplasma gondii histone deacetylase HDAC1 0.0617 0.1496 0.1496
Plasmodium falciparum transporter, putative 0.005 0.0098 0.0092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0652
Entamoeba histolytica recQ family DNA helicase 0.001 0.0001 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0033 0.0228
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0013 0.0076
Loa Loa (eye worm) hypothetical protein 0.0292 0.0695 0.4646
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0526 0.1272 0.9703
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0145
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi histone deacetylase 1 (HD1) 0.0526 0.1272 0.8502
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0026 0.0071
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0014
Schistosoma mansoni hypothetical protein 0.0082 0.0179 0.0535
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0015 0.0014 0.0043
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0015 0.0013 0.0082
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0026 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni patched 1 0.0125 0.0285 0.0854
Plasmodium vivax histone deacetylase, putative 0.026 0.0616 0.0616
Echinococcus multilocularis expressed conserved protein 0.0275 0.0652 0.1102
Brugia malayi Myosin head containing protein 0.0018 0.002 0.0121
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.008 0.0235
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0026 0.0159
Leishmania major hypothetical protein, unknown function 0.0015 0.0013 0.0047
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0128 0.0383
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0093 0.0279
Brugia malayi hypothetical protein 0.0018 0.002 0.0121
Brugia malayi DKFZp564C0469 protein 0.003 0.0049 0.0318
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0091
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.015 0.0964
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0013 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0082 0.0247
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.049
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0292 0.0696 0.5472
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.015 0.1176
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.0606 0.4046
Echinococcus granulosus tar DNA binding protein 0.0124 0.0282 0.084
Schistosoma mansoni jumonji domain containing protein 0.0058 0.012 0.0359
Brugia malayi hypothetical protein 0.0018 0.002 0.0121
Brugia malayi Histone deacetylase family protein 0.0617 0.1496 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Mycobacterium ulcerans hypothetical protein 0.0022 0.0031 0.0009
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0072 0.0153 0.0452
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.015 0.0264
Loa Loa (eye worm) hypothetical protein 0.0292 0.0696 0.465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0026 0.0165
Leishmania major DNA polymerase eta, putative 0.0097 0.0215 0.1404
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.015 0.0128
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi Fibronectin type III domain containing protein 0.0015 0.0014 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0091 0.0605
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0002 0.0001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0023 0.0062
Schistosoma mansoni hypothetical protein 0.0176 0.0409 0.1224
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0026 0.0159
Onchocerca volvulus 0.0021 0.0027 0.0308
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0049 0.0352
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0014 0.002
Onchocerca volvulus 0.002 0.0026 0.0286
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0028 0.0078
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.012 0.02
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0048 0.0042
Echinococcus granulosus tumor protein p63 0.0333 0.0797 0.2383
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0043 0.0083 0.0114
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Echinococcus granulosus histone deacetylase 6 0.0617 0.1496 0.4476
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0093 0.0273
Trypanosoma cruzi histone deacetylase 1, putative 0.0526 0.1272 0.8503
Schistosoma mansoni ets-related 0.001 0.0002 0.0006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0026 0.0077
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0136
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0043 0.0083 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Loa Loa (eye worm) TAR-binding protein 0.0124 0.0282 0.1882
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0106 0.0084
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0069 0.0069
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0218 0.1423
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Echinococcus granulosus replication factor c subunit 1 0.003 0.0049 0.0142
Onchocerca volvulus Histone deacetylase 10 homolog 0.026 0.0616 0.8849
Echinococcus granulosus Immunoglobulin 0.0015 0.0014 0.0037
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0031 0.0169
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Echinococcus granulosus dna polymerase eta 0.0097 0.0215 0.0639
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0013 0.0082
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0099 0.0656
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Trypanosoma brucei histone deacetylase 2 0.026 0.0616 0.4096
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0242 0.0453
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0027 0.0005
Brugia malayi Ets-domain containing protein 0.0072 0.0153 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Schistosoma mansoni glutaminase 0.0542 0.1311 0.3925
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0125 0.0285 0.1901
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Echinococcus multilocularis histone deacetylase 6 0.0629 0.1525 0.2581
Echinococcus granulosus histone deacetylase 7 0.0617 0.1496 0.4476
Leishmania major importin beta-1 subunit, putative 0.0023 0.0033 0.0182
Echinococcus multilocularis dna polymerase eta 0.0097 0.0215 0.0361
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0098 0.0289
Brugia malayi Patched related family protein 4 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Leishmania major DNA polymerase kappa, putative 0.0078 0.0169 0.1095
Loa Loa (eye worm) hypothetical protein 0.012 0.0271 0.1807
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0098 0.0289
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0015 0.0014 0.0037
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0025 0.0153
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.015 0.1176
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0069 0.0069
Plasmodium falciparum protoporphyrinogen oxidase 0.0043 0.0083 0.0077
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0321 0.0955
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0009
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0002 0.0006
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0027 0.0043
Entamoeba histolytica hypothetical protein 0.0177 0.0412 0.3242
Loa Loa (eye worm) histone deacetylase 0.0617 0.1496 1
Plasmodium falciparum flap endonuclease 1 0.0026 0.004 0.0034
Brugia malayi hypothetical protein 0.005 0.0099 0.065
Echinococcus multilocularis BRCA1 associated protein 0.0012 0.0006 0.0007
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0209 0.0492 0.0471
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0096 0.0289
Entamoeba histolytica protein kinase, putative 0.0177 0.0412 0.3242
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0031 0.0031
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0025 0.0164
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0026 0.004
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0046 0.0046
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0027 0.0027
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0031 0.0093
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0025 0.0153
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.034 0.2266
Brugia malayi Protein kinase domain containing protein 0.0177 0.0412 0.2748
Loa Loa (eye worm) hypothetical protein 0.005 0.0099 0.0656
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0098 0.0294
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0143
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.004 0.0277
Schistosoma mansoni hypothetical protein 0.0035 0.0062 0.0187
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0015 0.0013 0.0019
Brugia malayi nuclear hormone receptor 0.002 0.0026 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0031 0.0201
Loa Loa (eye worm) acetyltransferase 0.0144 0.033 0.2205
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0225 0.1495
Schistosoma mansoni hypothetical protein 0.0047 0.0091 0.0274
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0175
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0026 0.0077
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0039
Giardia lamblia Casein kinase II beta chain 0.0038 0.0069 0.0517
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0043 0.0083 0.0083
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0242 0.347
Schistosoma mansoni DNA helicase recq5 0.002 0.0025 0.0074
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0026 0.0286
Giardia lamblia DINP protein human, muc B family 0.0078 0.0169 0.1306
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0066 0.0192
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0014 0.002
Trypanosoma cruzi histone deacetylase, putative 0.026 0.0616 0.4115
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0027 0.0005
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0015 0.0013 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0114 0.0727
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0098 0.0294
Toxoplasma gondii hypothetical protein 0.0018 0.002 0.002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0027 0.0014
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0025 0.0159
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0099 0.0093
Plasmodium falciparum chorismate synthase 0.407 1 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0082 0.0545
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0412 0.3123
Schistosoma mansoni cpg binding protein 0.0057 0.0116 0.0347
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0027 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Brugia malayi glutaminase DH11.1 0.0542 0.1311 0.8761
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.034 0.2266
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0282 0.0845
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0072 0.0066
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0015 0.0044
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0066 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0133 0.0305 0.0582
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0636
Schistosoma mansoni brca1-associated protein (brap2) 0.0012 0.0006 0.0018
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0026 0.0165
Brugia malayi hypothetical protein 0.0035 0.0062 0.0405
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0049 0.0352
Loa Loa (eye worm) hypothetical protein 0.0526 0.1272 0.8503
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0242 0.1825
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0026 0.0159
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0027 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0096 0.0605
Entamoeba histolytica protein kinase domain containing protein 0.0177 0.0412 0.3242
Schistosoma mansoni apoptosis regulator bax 0.0082 0.0179 0.0535
Echinococcus multilocularis neuroglian 0.0015 0.0014 0.0021
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0133 0.0305 0.0582
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0083 0.0128
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0031 0.0201
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0002 0.0006
Entamoeba histolytica protein kinase, putative 0.0177 0.0412 0.3242
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0242 0.0724
Trypanosoma cruzi histone deacetylase, putative 0.0617 0.1496 1
Loa Loa (eye worm) Csnk2b protein 0.0038 0.0069 0.0454
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.015 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0082 0.0623
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0292 0.0695 0.4646
Onchocerca volvulus 0.0018 0.002 0.0203
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0015 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0014 0.0041
Leishmania major UDP-galactopyranose mutase 0.0043 0.0083 0.0517
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0202 0.1314
Leishmania major DNA damage repair protein, putative 0.0022 0.0031 0.0169
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0027 0.0182
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0052 0.0151
Schistosoma mansoni brca1-associated protein (brap2) 0.0012 0.0006 0.0018
Leishmania major DNA polymerase eta, putative 0.0048 0.0093 0.0587
Loa Loa (eye worm) hypothetical protein 0.0369 0.0886 0.5918
Brugia malayi SWIRM domain containing protein 0.0043 0.0083 0.0542
Echinococcus granulosus intestinal type alkaline phosphatase 0.0161 0.0374 0.1114
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.015 0.0128
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0027 0.0169
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0069 0.0541
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0324
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0098 0.0294
Echinococcus multilocularis Niemann Pick C1 protein 0.0418 0.1005 0.1699
Onchocerca volvulus 0.0043 0.0083 0.1116
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0096 0.0605
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0027 0.0081
Schistosoma mansoni hypothetical protein 0.0084 0.0183 0.0547
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0242 0.1612
Trypanosoma cruzi histone deacetylase, putative 0.0617 0.1496 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0046 0.0075
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0002 0.0003
Giardia lamblia Histone deacetylase 0.0526 0.1272 1
Loa Loa (eye worm) histone deacetylase 11 0.026 0.0616 0.4115
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0082 0.0179 0.1183
Brugia malayi hypothetical protein 0.0015 0.0014 0.0083
Onchocerca volvulus 0.0018 0.002 0.0203
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Brugia malayi protein C24B5.3 0.0018 0.002 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0012 0.0006 0.0046
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0066 0.0192
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0034
Echinococcus multilocularis geminin 0.0176 0.0409 0.0689
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0724 0.4838
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0209 0.0492 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0026 0.004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Toxoplasma gondii hypothetical protein 0.005 0.0098 0.0098
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0082 0.0545
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.015 0.0964
Echinococcus multilocularis histone deacetylase 8 0.026 0.0616 0.1041
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0099 0.0656
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0052 0.0157
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0128 0.0378
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0169 0.1095
Schistosoma mansoni hypothetical protein 0.0047 0.0091 0.0274
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0043 0.0082 0.0545
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0242 0.1825
Brugia malayi hypothetical protein 0.0043 0.0083 0.0542
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0038 0.0069 0.0422
Brugia malayi Pre-SET motif family protein 0.0208 0.0488 0.3254
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0015 0.0013 0.0019
Schistosoma mansoni amine oxidase 0.0043 0.0083 0.0248
Toxoplasma gondii ck2 beta subunit 0.0038 0.0069 0.0069
Brugia malayi hypothetical protein 0.003 0.0049 0.0318
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.0147
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0026 0.0077
Echinococcus granulosus histone deacetylase 0.0617 0.1496 0.4476
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Brugia malayi casein kinase II, putaitve 0.0011 0.0003 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0026 0.0071
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0015 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.0808 0.1967 0.3329
Trypanosoma cruzi histone deacetylase, putative 0.0617 0.1496 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0098 0.0289
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0012 0.0006 0.0033
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0002 0.0006
Brugia malayi Ets-domain containing protein 0.0072 0.0153 0.101
Plasmodium vivax SET domain protein, putative 0.0031 0.0052 0.0052
Trypanosoma brucei unspecified product 0.0049 0.0098 0.0618
Onchocerca volvulus 0.0018 0.002 0.0203
Plasmodium falciparum protein kinase 5 0.0043 0.0082 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0026 0.0159
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0098 0.0289
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0015 0.0013 0.0013
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0098 0.0051
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0048 0.0048
Trypanosoma brucei chrX additional, unordered contigs 0.0022 0.0031 0.0169
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0048 0.0048
Onchocerca volvulus 0.007 0.015 0.2084
Brugia malayi Pre-SET motif family protein 0.0031 0.0052 0.0337
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0026 0.0159
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0031 0.0169
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0177 0.0412 0.2728
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0082 0.0179 0.053
Brugia malayi polk-prov protein 0.0049 0.0096 0.0631
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0052 0.0085
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0025 0.0164
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0026 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.015 0.0264
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0247 0.0584 0.1743
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0013 0.0076
Schistosoma mansoni histone deacetylase 4 5 0.0617 0.1496 0.4479
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.008 0.059
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.015 0.0128
Loa Loa (eye worm) hypothetical protein 0.007 0.015 0.0994
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0282 0.0845
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0091 0.0152
Schistosoma mansoni flap endonuclease-1 0.0023 0.0033 0.01
Schistosoma mansoni topbp1 0.003 0.0049 0.0148
Brugia malayi Protein kinase domain containing protein 0.0043 0.0082 0.0539
Loa Loa (eye worm) norepinephrine transporter 0.0292 0.0695 0.4646
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0048 0.0048
Loa Loa (eye worm) casein kinase II 0.0011 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0027 0.0014
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0027 0.0014
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.025 0.0592 0.1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.008 0.059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.2007 0.4919 1
Schistosoma mansoni cell adhesion molecule 0.0015 0.0014 0.0043
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0048 0.0048
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0015 0.0015
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0615 0.149 0.1471
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0106 0.0175
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0105 0.0234 0.1557
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0025 0.0126
Trypanosoma cruzi histone deacetylase, putative 0.026 0.0616 0.4115
Echinococcus granulosus cyclin dependent kinase 0.0043 0.0082 0.0241
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0701
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0091 0.0268
Schistosoma mansoni vesicular amine transporter 0.0015 0.0014 0.0043
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0083 0.0243
Entamoeba histolytica recQ family helicase, putative 0.002 0.0025 0.0194
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0093 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0066 0.048
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0106 0.0058
Trypanosoma brucei histone deacetylase 4 0.0617 0.1496 1
Toxoplasma gondii histone deacetylase HDAC3 0.0526 0.1272 0.1272
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0066 0.0495
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0015 0.0013 0.0039
Echinococcus granulosus BRCA1 associated protein 0.0012 0.0006 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0026 0.0159
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.049
Schistosoma mansoni hypothetical protein 0.0304 0.0724 0.2168
Brugia malayi Flap endonuclease-1 0.0026 0.004 0.0252
Echinococcus multilocularis histone deacetylase 6 0.0617 0.1496 0.2531
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0099 0.0099
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0027 0.0175
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0082 0.0545
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0002 0.0006
Loa Loa (eye worm) solute carrier family 6 member 4 0.0292 0.0695 0.4646
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0106 0.01
Schistosoma mansoni hypothetical protein 0.0101 0.0225 0.0674
Onchocerca volvulus Protein patched homolog 0.0018 0.002 0.0203
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0282 0.0845
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0343 0.0821 0.1623
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0027 0.0169
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0128 0.085
Schistosoma mansoni histone deacetylase hda2 0.026 0.0616 0.1845
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0652
Loa Loa (eye worm) hypothetical protein 0.0257 0.061 0.4074
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0646
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0025 0.0039
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0048 0.0678
Schistosoma mansoni nephrin 0.0015 0.0014 0.0043
Brugia malayi hypothetical protein 0.0011 0.0002 0.0003
Onchocerca volvulus 0.0018 0.002 0.0203
Brugia malayi 6-phosphofructokinase 0.0108 0.0242 0.1608
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0069 0.0454
Loa Loa (eye worm) hypothetical protein 0.0043 0.0083 0.0548
Toxoplasma gondii patched family protein 0.0018 0.002 0.002
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0049 0.0318
Schistosoma mansoni alkaline phosphatase 0.0161 0.0374 0.1119
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0343 0.0821 0.0777
Echinococcus multilocularis muscleblind protein 0.0443 0.1068 0.1807
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.012 0.0354
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0175
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0027 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0418 0.1005 0.3006
Onchocerca volvulus 0.005 0.0098 0.1341
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0093 0.061
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0027 0.0014
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0049 0.008
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0043 0.0083 0.0077
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0701
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.003 0.0049 0.0578
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0268 0.1787
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Schistosoma mansoni elf1 0.001 0.0002 0.0006
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0049 0.0324
Loa Loa (eye worm) hypothetical protein 0.0138 0.0317 0.2112
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0013 0.0049
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0098 0.0289
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.015 0.025
Mycobacterium ulcerans chorismate synthase 0.407 1 1
Plasmodium vivax chorismate synthase 0.407 1 1
Loa Loa (eye worm) fli-1 protein 0.0218 0.0512 0.342
Mycobacterium ulcerans glutaminase 0.0542 0.1311 0.1291
Chlamydia trachomatis dehyroquinate synthase 0.0133 0.0305 0.0258
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0128 0.0383
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0069 0.0541
Entamoeba histolytica Flap nuclease, putative 0.0026 0.004 0.0311
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0066 0.043
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0082 0.0605
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0083 0.0243
Schistosoma mansoni DNA helicase recq1 0.002 0.0025 0.0074
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0082 0.0605
Loa Loa (eye worm) hypothetical protein 0.026 0.0616 0.4115
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.004 0.0286
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0022 0.0132
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0389 0.556
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0052 0.0157
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0015 0.0013 0.0049
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0047 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.003 0.0049 0.0027
Brugia malayi hypothetical protein 0.012 0.0271 0.1802
Brugia malayi Patched protein homolog 1 0.0018 0.002 0.0121
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0119 0.0269 0.0807
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0652
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0015 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.009
Brugia malayi Fli-1 protein 0.0218 0.0512 0.3416
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.0013 0.0082
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0027 0.0182
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0027 0.0014
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0015 0.0009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0218 0.1451
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.0282 0.1877
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0025 0.0153
Schistosoma mansoni cpg binding protein 0.006 0.0124 0.0371
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0016
Echinococcus multilocularis GPCR, family 2 0.0047 0.0091 0.0152
Loa Loa (eye worm) patched family protein 0.0018 0.002 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Echinococcus granulosus twitchin 0.0017 0.0018 0.0047
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0247 0.0584 0.0986
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0027 0.0005
Entamoeba histolytica hypothetical protein 0.0023 0.0033 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Echinococcus multilocularis Niemann Pick C1 protein 0.0292 0.0696 0.1176
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0099 0.0099
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.015 0.0128
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0026 0.0077
Mycobacterium ulcerans hypothetical protein 0.007 0.015 0.0128
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0343
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0175
Plasmodium vivax JmjC domain containing protein 0.0016 0.0015 0.0015
Loa Loa (eye worm) histone deacetylase 3 0.0526 0.1272 0.8503
Schistosoma mansoni importin beta-1 0.0028 0.0046 0.0139
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0218 0.1451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0026 0.0165
Echinococcus multilocularis tar DNA binding protein 0.0124 0.0282 0.0475
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0015 0.0014 0.0021
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0026 0.0071
Onchocerca volvulus 0.0015 0.0013 0.0101
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0343 0.0821 0.08
Schistosoma mansoni gabp alpha 0.0072 0.0153 0.0458
Brugia malayi CHE-14 protein 0.0125 0.0285 0.1896
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0015 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0022 0.0004
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0114 0.0727
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0026 0.0159
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0066 0.0109
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0153 0.0452
Toxoplasma gondii patched family protein 0.0018 0.002 0.002
Trypanosoma brucei histone deacetylase 3 0.0617 0.1496 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0028 0.0044
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0133 0.0305 0.0283
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0133 0.0305 0.0568
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Brugia malayi topoisomerase 0.003 0.0049 0.0318
Onchocerca volvulus 0.0236 0.0558 0.801
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0082 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0389 0.2952
Echinococcus multilocularis roundabout 2 0.0015 0.0014 0.0021
Trypanosoma brucei histone deacetylase, putative 0.0617 0.1496 1
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0072 0.054
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.2007 0.4919 1
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.033 0.22
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0027 0.0076
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0145
Loa Loa (eye worm) hypothetical protein 0.007 0.015 0.0994
Leishmania major GTP-binding protein, putative 0.0021 0.0028 0.0147
Onchocerca volvulus 0.0049 0.0096 0.1313
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0436
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0242 0.1825
Onchocerca volvulus 0.0292 0.0695 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0018 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Echinococcus multilocularis protein dispatched 1 0.0143 0.0329 0.0554
Onchocerca volvulus 0.003 0.0049 0.063
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0026 0.004
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.003 0.0049 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0035
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0015 0.0014 0.0043
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0025 0.0126
Brugia malayi hypothetical protein 0.015 0.0346 0.2301
Brugia malayi jmjC domain containing protein 0.0062 0.0128 0.0844
Loa Loa (eye worm) hypothetical protein 0.0105 0.0234 0.1562
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0026 0.0071
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0175
Brugia malayi Importin beta-1 subunit 0.0028 0.0046 0.0298
Treponema pallidum sodium- and chloride- dependent transporter 0.0292 0.0695 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0026 0.0077
Echinococcus granulosus geminin 0.0176 0.0409 0.1219
Echinococcus granulosus casein kinase ii subunit beta 0.0038 0.0069 0.0201
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0142
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.0606 0.4043
Onchocerca volvulus 0.0057 0.0116 0.1597
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0031 0.0169
Brugia malayi Niemann-Pick C1 protein precursor 0.0292 0.0696 0.4647
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0009
Echinococcus granulosus flap endonuclease 1 0.0026 0.004 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Brugia malayi hypothetical protein 0.0032 0.0055 0.0359
Schistosoma mansoni thyroid hormone receptor 0.002 0.0026 0.0077
Loa Loa (eye worm) hypothetical protein 0.0357 0.0856 0.572
Brugia malayi CXXC zinc finger family protein 0.0057 0.0116 0.0764
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0083 0.0128
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0027 0.0175
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Toxoplasma gondii histone deacetylase HDAC5 0.026 0.0616 0.0616
Echinococcus granulosus cyclin dependent kinase 5 0.0043 0.0082 0.0241
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0015 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0098 0.0646
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0027 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0292 0.0696 0.208
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0049 0.0352
Schistosoma mansoni hypothetical protein 0.0121 0.0274 0.0821
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Giardia lamblia DNA damage repair protein 0.0022 0.0031 0.0219
Loa Loa (eye worm) hypothetical protein 0.0053 0.0106 0.0701
Entamoeba histolytica hypothetical protein 0.0035 0.0062 0.049
Brugia malayi amine oxidase, flavin-containing family protein 0.0043 0.0083 0.0542
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0026 0.0165
Echinococcus granulosus muscleblind protein 0.0443 0.1068 0.3196
Echinococcus multilocularis muscleblind protein 1 0.0443 0.1068 0.1807
Echinococcus granulosus bloom syndrome protein 0.002 0.0025 0.0068
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.015 0.025
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0242 0.1584
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0049 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0035
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0292 0.0695 0.4643
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0606 0.4608
Brugia malayi AMP-binding enzyme family protein 0.007 0.015 0.0989
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0165
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0083 0.0548
Schistosoma mansoni ets-related 0.0218 0.0512 0.1534
Schistosoma mansoni nuclear hormone receptor 0.002 0.0026 0.0077
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0218 0.0196
Trichomonas vaginalis histone deacetylase, putative 0.0526 0.1272 0.9703
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0098 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0218 0.1423
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0114 0.0727
Onchocerca volvulus 0.005 0.0098 0.1341
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0069 0.0501
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0082 0.0545
Schistosoma mansoni hypothetical protein 0.0082 0.0179 0.0535
Loa Loa (eye worm) hypothetical protein 0.0101 0.0225 0.15
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0027 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0218 0.1451
Echinococcus granulosus Protein patched homolog 1 0.0125 0.0285 0.0849
Plasmodium vivax histone deacetylase 2, putative 0.0617 0.1496 0.1496
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0027 0.0143
Onchocerca volvulus 0.0021 0.0027 0.0308
Onchocerca volvulus 0.0018 0.002 0.0203
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0161 0.0374 0.1114
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.0013 0.0049
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0025 0.0159
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0015 0.0091
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0082 0.0647
Brugia malayi jmjC domain containing protein 0.0016 0.0015 0.0085
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0017 0.0018 0.0113
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0043 0.0082 0.0082
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0091 0.0605
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.0013 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0026 0.0159
Brugia malayi jmjC domain containing protein 0.0016 0.0015 0.0085
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0025 0.0169
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0015 0.0013 0.0013
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0043 0.0082 0.0513
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0049 0.0324
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0066 0.0198
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0026 0.0286
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0015 0.0013 0.0103
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0242 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0099 0.016
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0066 0.0404
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0013 0.0007
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0082 0.0179 0.053
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0242 0.1584
Schistosoma mansoni hypothetical protein 0.0121 0.0274 0.0821
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0052 0.0052
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0098 0.0098
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0027 0.0005
Loa Loa (eye worm) glutaminase 2 0.0542 0.1311 0.8762
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.015 0.0964
Brugia malayi Patched family protein 0.0018 0.002 0.0121
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0552 0.1335 0.3995
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0127
Echinococcus granulosus importin subunit beta 1 0.0028 0.0046 0.0133
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0048 0.0093 0.0093

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 238 nM Inhibition of high affinity uptake by the serotonin transporter (5-HT) from rat synaptosomal nerve endings by using [3H]-5-HT as radioligand ChEMBL. 15537337
Ki (binding) = 238 nM Inhibition of high affinity uptake by the serotonin transporter (5-HT) from rat synaptosomal nerve endings by using [3H]-5-HT as radioligand ChEMBL. 15537337
Ki (binding) = 376 nM Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]-DA as radioligand ChEMBL. 15537337
Ki (binding) = 376 nM Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]-DA as radioligand ChEMBL. 15537337
Ki (binding) = 424 nM Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]-NE as radioligand ChEMBL. 15537337
Ki (binding) = 424 nM Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]-NE as radioligand ChEMBL. 15537337

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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