Detailed information for compound 337138

Basic information

Technical information
  • TDR Targets ID: 337138
  • Name: N-(1-adamantyl)dodecanamide
  • MW: 333.551 | Formula: C22H39NO
  • H donors: 1 H acceptors: 1 LogP: 7.37 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCC(=O)NC12CC3CC(C2)CC(C1)C3
  • InChi: 1S/C22H39NO/c1-2-3-4-5-6-7-8-9-10-11-21(24)23-22-15-18-12-19(16-22)14-20(13-18)17-22/h18-20H,2-17H2,1H3,(H,23,24)
  • InChiKey: FRFKXRWIBACCCN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(1-adamantyl)lauramide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References
Homo sapiens epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans epoxide hydrolase EphA Get druggable targets OG5_129061 All targets in OG5_129061
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Get druggable targets OG5_129061 All targets in OG5_129061
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni jumonji/arid domain-containing protein 0.0314 0.2023 0.1999
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.034 0.035
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0047 0.0086 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Entamoeba histolytica tubulin family protein 0.0049 0.0102 0.2332
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0395 0.2606 0.304
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.014 0.0323
Loa Loa (eye worm) hypothetical protein 0.0923 0.6433 0.7496
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0447 0.2987 0.4644
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.1125 0.1098
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus granulosus lysine specific demethylase 5A 0.0314 0.2023 0.2247
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.1263 0.89 1
Toxoplasma gondii beta tubulin 0.0049 0.0102 0.0204
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Loa Loa (eye worm) beta-lactamase 0.019 0.1125 0.1274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Giardia lamblia Reductase, putative 0.0047 0.0086 0.3356
Mycobacterium ulcerans oxidoreductase 0.0047 0.0086 0.0159
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0111 0.0233
Mycobacterium tuberculosis Probable oxidoreductase 0.038 0.2502 0.2918
Echinococcus granulosus ecdysone induced protein 78C 0.0447 0.2987 0.3334
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) hypothetical protein 0.0157 0.0884 0.0993
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0086 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0211 0.1275 0.1403
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Leishmania major short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Brugia malayi nuclear receptor NHR-88 0.0447 0.2987 0.4644
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Echinococcus multilocularis glutamate receptor 2 0.0131 0.0692 0.0746
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0447 0.2987 0.2966
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0118 0.0599 0.0692
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0235 0.0231
Brugia malayi RNA, U transporter 1 0.0177 0.1029 0.16
Schistosoma mansoni tyrosine kinase 0.0069 0.0245 0.0216
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis beta tubulin 0.0049 0.0102 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0447 0.2987 0.4644
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Leishmania major extracellular receptor, putative 0.0067 0.0231 0.0609
Schistosoma mansoni glutamate receptor AMPA 0.0131 0.0692 0.0664
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0131 0.0692 0.0746
Mycobacterium tuberculosis Probable conserved lipoprotein 0.019 0.1125 0.1307
Loa Loa (eye worm) hypothetical protein 0.0068 0.024 0.0237
Schistosoma mansoni alpha-glucosidase 0.0318 0.2053 0.2029
Brugia malayi Nuclear hormone receptor E75 0.0211 0.1275 0.1981
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0047 0.0086 0.0159
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0102 0.0204
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0078 0.0054
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Entamoeba histolytica hypothetical protein, conserved 0.0047 0.0086 0.1802
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0235 0.0365
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0078 0.0054
Onchocerca volvulus 0.0047 0.0086 0.0049
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni tyrosine kinase 0.0217 0.1319 0.1293
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4897
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable lipase LipE 0.019 0.1125 0.1307
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis jumonji domain containing 1A 0.0084 0.0353 0.0364
Echinococcus granulosus caspase 2 0.0923 0.6433 0.7218
Brugia malayi nuclear receptor NHR-67 0.0211 0.1275 0.1981
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0236 0.1458 0.1665
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus granulosus nuclear receptor nhr 48 0.0211 0.1275 0.1403
Brugia malayi Nuclear hormone receptor-like 1 0.0236 0.1458 0.2267
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0058 0.0164 0.1037
Echinococcus granulosus WW domain containing oxidoreductase 0.0047 0.0086 0.0063
Loa Loa (eye worm) dehydrogenase 0.0047 0.0086 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0084 0.0353 0.0364
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.029 0.1848 0.2872
Brugia malayi hypothetical protein 0.0236 0.1458 0.2267
Schistosoma mansoni aldehyde dehydrogenase 0.046 0.3076 0.3055
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0119 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0447 0.2987 0.4644
Echinococcus granulosus lysosomal alpha glucosidase 0.037 0.2426 0.2701
Trypanosoma brucei oxidoreductase-like protein 0.0047 0.0086 0.0152
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma cruzi beta tubulin, putative 0.0049 0.0102 0.0204
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Schistosoma mansoni nuclear hormone receptor 0.0447 0.2987 0.2966
Brugia malayi Furin-like cysteine rich region family protein 0.0191 0.1129 0.1755
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.052
Schistosoma mansoni importin beta-1 0.0062 0.0197 0.0167
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4897
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Leishmania major short chain dehydrogenase-like protein 0.0047 0.0086 0.0152
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni caspase-7 (C14 family) 0.1263 0.89 0.8897
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0047 0.0086 0.0063
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Toxoplasma gondii carbonyl reductase 1, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable reductase 0.0118 0.0599 0.0692
Onchocerca volvulus 0.019 0.1125 0.1257
Brugia malayi hypothetical protein 0.0636 0.4357 0.6774
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Schistosoma mansoni tyrosine kinase 0.0209 0.1263 0.1237
Loa Loa (eye worm) hypothetical protein 0.01 0.0468 0.0505
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Mycobacterium ulcerans esterase/lipase LipP 0.019 0.1125 0.3578
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus granulosus hypothetical protein 0.0047 0.0086 0.0063
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0246 0.1525 1
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0047 0.0086 0.052
Brugia malayi hypothetical protein 0.0067 0.0231 0.0358
Onchocerca volvulus 0.0047 0.0086 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Brugia malayi orphan nuclear receptor NR2E1 0.0211 0.1275 0.1981
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.037 0.2426 0.2701
Plasmodium vivax hypothetical protein, conserved 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Loa Loa (eye worm) TK/INSR protein kinase 0.0062 0.0192 0.0181
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6433
Echinococcus granulosus beta tubulin 0.0049 0.0102 0.0082
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0102 0.0204
Brugia malayi hypoxia-induced factor 1 0.049 0.3295 0.5123
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0067 0.0231 0.0226
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0335 0.2172 0.2532
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni tyrosine kinase 0.0103 0.0492 0.0463
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0007
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0447 0.2987 0.3458
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0236 0.1458 0.1432
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0047 0.0086 0.1802
Brugia malayi beta-tubulin, identical 0.0049 0.0102 0.0159
Brugia malayi hypothetical protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0447 0.2987 0.3458
Echinococcus multilocularis retinol dehydrogenase 11 0.0047 0.0086 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Brugia malayi Nuclear hormone receptor-like 1 0.0447 0.2987 0.4644
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Schistosoma mansoni peptidase Clp (S14 family) 0.0246 0.1525 0.15
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0403 0.2669 0.8661
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0335 0.2172 0.7026
Schistosoma mansoni metabotropic glutamate receptor 0.0067 0.0231 0.0201
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.026 0.1628 0.1802
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.1125 0.3429
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0067 0.0231 0.0226
Trypanosoma brucei hypothetical protein, conserved 0.019 0.1125 0.3429
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) hypothetical protein 0.0636 0.4357 0.5063
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0047 0.0086 0.0092
Onchocerca volvulus 0.0047 0.0086 0.0049
Echinococcus granulosus peptidase Clp S14 family 0.0161 0.0912 0.0994
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0131 0.0692 0.0746
Echinococcus granulosus Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0086 0.0027
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Brugia malayi Inositol-1 0.004 0.0038 0.0058
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0038 0.0009
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0047 0.0086 0.0152
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0157 0.0884 0.2672
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0103 0.0492 0.0521
Schistosoma mansoni aryl hydrocarbon receptor 0.0158 0.0892 0.0865
Brugia malayi hypothetical protein 0.0211 0.1275 0.1981
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0047 0.0086 0.0159
Brugia malayi hypothetical protein 0.0531 0.3594 0.5587
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Schistosoma mansoni tyrosine kinase 0.0062 0.0192 0.0163
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0236 0.1458 0.161
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.052
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0067 0.0231 0.0358
Echinococcus granulosus metabotropic glutamate receptor 5 0.0067 0.0231 0.0226
Echinococcus granulosus beta LACTamase domain containing family member 0.019 0.1125 0.1234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0447 0.2987 0.3458
Leishmania major hypothetical protein, conserved 0.019 0.1125 0.3429
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.046 0.3076 0.3434
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.1125 0.1098
Echinococcus granulosus beta tubulin 0.0049 0.0102 0.0082
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Echinococcus granulosus caspase 0.1263 0.89 1
Loa Loa (eye worm) glutathione reductase 0.0052 0.0119 0.0096
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Echinococcus granulosus glutamate receptor 2 0.0198 0.1177 0.1294
Echinococcus multilocularis nmda type glutamate receptor 0.0466 0.3119 0.3483
Echinococcus granulosus importin subunit beta 1 0.0062 0.0197 0.0188
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.1228 0.8648 1
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0047 0.0086 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Plasmodium vivax importin-beta 2, putative 0.0062 0.0197 0.0381
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.1125 0.1257
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Leishmania major protein kinase, putative 0.0045 0.0073 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Brugia malayi hypothetical protein 0.0445 0.297 0.4617
Loa Loa (eye worm) glutamate receptor 1 0.0131 0.0692 0.0767
Echinococcus granulosus glutamate receptor 2 0.0067 0.0231 0.0226
Leishmania major 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0447 0.2987 0.4644
Loa Loa (eye worm) TK/EGFR protein kinase 0.0191 0.1129 0.1279
Brugia malayi nuclear receptor NHR-88 0.0211 0.1275 0.1981
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Brugia malayi glutathione reductase 0.0052 0.0119 0.0186
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0466 0.3119 0.3483
Echinococcus multilocularis lysine specific demethylase 5A 0.0314 0.2023 0.2247
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0193 0.1141 0.1275
Entamoeba histolytica tubulin family protein 0.0049 0.0102 0.2332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0447 0.2987 0.4644
Echinococcus multilocularis nmda type glutamate receptor 0.0067 0.0231 0.0226
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0314 0.2023 0.2247
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.1263 0.89 1
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0119 0.0096
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.014 0.0199
Echinococcus multilocularis thyroid hormone receptor alpha 0.0447 0.2987 0.3334
Entamoeba histolytica hypothetical protein 0.0051 0.0111 0.2624
Trypanosoma brucei glucosidase, putative 0.0082 0.034 0.0954
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0078 0.012
Trypanosoma cruzi short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0047 0.0086 0.0092
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0236 0.1458 0.1432
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Schistosoma mansoni protein kinase 0.0069 0.0245 0.0216
Schistosoma mansoni tyrosine kinase 0.0103 0.0492 0.0463
Echinococcus granulosus phd:f box containing protein 0.0084 0.0353 0.0364
Plasmodium vivax hypothetical protein, conserved 0.019 0.1125 0.3345
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.019 0.1125 0.1748
Loa Loa (eye worm) dehydrogenase 0.0047 0.0086 0.0057
Loa Loa (eye worm) DR-78 0.0211 0.1275 0.145
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0447 0.2987 0.4644
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0047 0.0086 0.0063
Schistosoma mansoni phosphatidylserine receptor 0.0084 0.0353 0.0324
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0047 0.0086 0.0092
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0047 0.0086 0.0152
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0403 0.2669 0.2975
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0047 0.0086 0.0027
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Plasmodium falciparum metacaspase 1 0.0478 0.3208 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus multilocularis nuclear receptor nhr 48 0.0211 0.1275 0.1403
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni thyroid hormone receptor 0.0447 0.2987 0.2966
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0197 0.0188
Mycobacterium leprae conserved hypothetical protein 0.019 0.1125 0.7361
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Leishmania major short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Trichomonas vaginalis tubulin gamma chain, putative 0.0049 0.0102 0.0204
Onchocerca volvulus 0.0047 0.0086 0.0049
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0047 0.0086 0.0159
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Schistosoma mansoni glutamate receptor AMPA 0.0131 0.0692 0.0664
Schistosoma mansoni inositol monophosphatase 0.004 0.0038 0.0008
Onchocerca volvulus 0.019 0.1125 0.1257
Schistosoma mansoni hypothetical protein 0.0131 0.0692 0.0664
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0447 0.2987 0.4644
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0447 0.2987 0.2966
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0047 0.0086 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.014 0.0323
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Mycobacterium ulcerans hydrolase/amidase 0.0333 0.2161 0.6989
Brugia malayi hypothetical protein 0.0211 0.1275 0.1981
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0447 0.2987 0.3334
Brugia malayi Steroid receptor seven-up type 2 0.0447 0.2987 0.4644
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Trypanosoma brucei metacaspase MCA2 0.0478 0.3208 1
Brugia malayi conserved hypotetical protein 0.0211 0.1275 0.1981
Echinococcus multilocularis transfer RNA-Lys 0.0117 0.0594 0.0636
Brugia malayi Dehydrogenases, short chain protein 2 0.0047 0.0086 0.0133
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Plasmodium falciparum glutathione reductase 0.0052 0.0119 0.0134
Loa Loa (eye worm) hypothetical protein 0.0193 0.1141 0.1293
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0069 0.0245 0.0235
Echinococcus multilocularis caspase 0.1263 0.89 1
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0198 0.1177 0.1294
Schistosoma mansoni hypothetical protein 0.0068 0.024 0.021
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0447 0.2987 0.3334
Echinococcus granulosus steroid dehydrogenase 0.0047 0.0086 0.0063
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0447 0.2987 0.2966
Schistosoma mansoni nuclear receptor 0.0211 0.1275 0.1248
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Onchocerca volvulus 0.0047 0.0086 0.0049
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0047 0.0086 0.1802
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0447 0.2987 0.4644
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0211 0.1275 0.1431
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0246 0.1525 0.4625
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Toxoplasma gondii beta-tubulin, putative 0.0049 0.0102 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Toxoplasma gondii hypothetical protein 0.0085 0.0358 0.1012
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0047 0.0086 0.0152
Brugia malayi nuclear receptor RXR 0.0236 0.1458 0.2267
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0211 0.1275 0.145
Mycobacterium ulcerans beta-lactamase 0.019 0.1125 0.3578
Loa Loa (eye worm) MH2 domain-containing protein 0.0398 0.2629 0.3037
Schistosoma mansoni hypothetical protein 0.054 0.3657 0.3638
Echinococcus multilocularis apoptotic protease activating factor 1 0.0445 0.297 0.3315
Schistosoma mansoni protein phosphatase 2C 0.0084 0.0353 0.0324
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.034 1
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0041 0.0043 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0447 0.2987 0.3422
Schistosoma mansoni jumonji/arid domain-containing protein 0.0314 0.2023 0.1999
Leishmania major dehydrogenase-like protein 0.0047 0.0086 0.0152
Echinococcus multilocularis retinol dehydrogenase 11 0.0047 0.0086 0.0063
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0131 0.0694 0.0804
Brugia malayi nuclear hormone receptor 0.0211 0.1275 0.1981
Brugia malayi Probable ClpP-like protease 0.0246 0.1525 0.2371
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Brugia malayi beta-lactamase 0.019 0.1125 0.1748
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis tyrosine protein kinase shark 0.0217 0.1319 0.1454
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0078 0.0047
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6961
Loa Loa (eye worm) hypothetical protein 0.067 0.4602 0.535
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.034 0.0954
Schistosoma mansoni nuclear receptor 0.0211 0.1275 0.1248
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0047 0.0086 0.0092
Entamoeba histolytica Ran family GTPase 0.0046 0.0078 0.1534
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0047 0.0086 0.0057
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0358 0.0898
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0049 0.0102 0.0082
Loa Loa (eye worm) steroid hormone receptor 0.0447 0.2987 0.3458
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Echinococcus multilocularis caspase 8 0.0478 0.3208 0.3583
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0468 0.0505
Mycobacterium tuberculosis Probable esterase LipL 0.019 0.1125 0.1307
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0356 0.2328 0.2685
Echinococcus granulosus epidermal growth factor receptor 0.0103 0.0492 0.0521
Loa Loa (eye worm) transcription factor SMAD2 0.0398 0.2629 0.3037
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0447 0.2987 0.4644
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.019 0.1125 0.1307
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.034 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0041 0.0043 0.0007
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0084 0.0353 0.0994
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0047 0.0086 0.0133
Loa Loa (eye worm) beta-tubulin 0.0049 0.0102 0.0076
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0236 0.1454 0.1605
Echinococcus multilocularis retinol dehydrogenase 13 0.0047 0.0086 0.0063
Echinococcus granulosus caspase 8 0.0478 0.3208 0.3583
Echinococcus multilocularis ecdysone induced protein 78C 0.0447 0.2987 0.3334
Echinococcus multilocularis caspase 2 0.0923 0.6433 0.7218
Leishmania major protein kinase, putative 0.0041 0.0043 0.0018
Entamoeba histolytica short chain dehydrogenase family protein 0.0047 0.0086 0.1802
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Loa Loa (eye worm) hypothetical protein 0.0531 0.3594 0.4168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0447 0.2987 0.3458
Brugia malayi tailless protein 0.0211 0.1275 0.1981
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0131 0.0692 0.0746
Brugia malayi jmjC domain containing protein 0.0314 0.2023 0.3145
Brugia malayi nuclear hormone receptor family member odr-7 0.0211 0.1275 0.1981
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus granulosus retinol dehydrogenase 11 0.0047 0.0086 0.0063
Brugia malayi dehydrogenases, short chain protein 9 0.0047 0.0086 0.0133
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.034 0.0954
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Trypanosoma brucei metacaspase 0.0478 0.3208 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0447 0.2987 0.3334
Brugia malayi metabotropic glutamate receptor type 2 0.0067 0.0231 0.0358
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi dehydrogenases, short chain protein 2 0.0047 0.0086 0.0133
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Echinococcus multilocularis conserved hypothetical protein 0.0047 0.0086 0.0063
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0161 0.0912 0.1058
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Onchocerca volvulus 0.0117 0.0594 0.064
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.014 0.0199
Echinococcus granulosus tubulin beta 1 chain 0.0049 0.0102 0.0082
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Brugia malayi PAS domain containing protein 0.0158 0.0892 0.1387
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Mycobacterium leprae Possible regulatory protein 0.0041 0.0043 0.024
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0067 0.0231 0.0226
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0102 0.0076
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Loa Loa (eye worm) hypothetical protein 0.0069 0.0245 0.0244
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0047 0.0086 0.0092
Brugia malayi Receptor family ligand binding region containing protein 0.0067 0.0231 0.0358
Echinococcus multilocularis phd:f box containing protein 0.0084 0.0353 0.0364
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0447 0.2987 0.2966
Echinococcus multilocularis oxidoreductase 0.0047 0.0086 0.0063
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium ulcerans dehydrogenase/reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis insulin receptor 0.0062 0.0192 0.0183
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Echinococcus granulosus atrial natriuretic peptide receptor 0.0067 0.0231 0.0226
Echinococcus granulosus aryl hydrocarbon receptor 0.0041 0.0043 0.0015
Schistosoma mansoni metabotropic glutamate receptor 0.0067 0.0231 0.0201
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.034 0.0954
Echinococcus granulosus single minded 2 0.0117 0.0594 0.0636
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0447 0.2987 0.2966
Loa Loa (eye worm) hypothetical protein 0.0445 0.297 0.3437
Onchocerca volvulus 0.0069 0.0245 0.0235
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0403 0.2669 0.4149
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0056
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.019 0.1125 0.1307
Brugia malayi oxidoreductase 0.0047 0.0086 0.0133
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0211 0.1275 0.1248
Echinococcus granulosus nmda type glutamate receptor 0.0067 0.0231 0.0226
Echinococcus granulosus epidermal growth factor receptor 0.0191 0.1129 0.1239
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0246 0.1525 0.1686
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0047 0.0086 0.0092
Leishmania major trypanothione reductase 0.0052 0.0119 0.0258
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0131 0.0692 0.0746
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Echinococcus granulosus muscleblind protein 0.067 0.4602 0.5154
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4625
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Toxoplasma gondii oxidoreductase, putative 0.0047 0.0086 0.0152
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0047 0.0086 0.0133
Echinococcus granulosus retinol dehydrogenase 11 0.0047 0.0086 0.0063
Leishmania major metacaspase, putative 0.0478 0.3208 1
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Mycobacterium ulcerans short-chain type oxidoreductase 0.0047 0.0086 0.0159
Trichomonas vaginalis tubulin beta chain, putative 0.0049 0.0102 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0043 0.0018
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0047 0.0086 0.3356
Mycobacterium tuberculosis Probable oxidoreductase 0.0131 0.0694 0.0804
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Schistosoma mansoni nuclear hormone receptor 0.0211 0.1275 0.1248
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.1125 0.3429
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0041 0.0043 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0131 0.0694 0.0804
Brugia malayi hypothetical protein 0.0054 0.014 0.0217
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0447 0.2987 0.3334
Onchocerca volvulus 0.0047 0.0086 0.0049
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.014 0.0323
Echinococcus granulosus glutamate receptor subunit protein glur 0.0131 0.0692 0.0746
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0119 0.0132
Plasmodium vivax metacaspase 1, putative 0.0478 0.3208 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Brugia malayi Melibiase family protein 0.0157 0.0884 0.1375
Trichomonas vaginalis tubulin, putative 0.0049 0.0102 0.0204
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Schistosoma mansoni alpha glucosidase 0.0082 0.034 0.0311
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Echinococcus granulosus insulin receptor 0.0062 0.0192 0.0183
Echinococcus granulosus tubulin subunit beta 0.0049 0.0102 0.0082
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.019 0.1125 0.1274
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0403 0.2669 0.2647
Schistosoma mansoni phd/f-box containing protein 0.0084 0.0353 0.0324
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi RNA binding protein 0.0068 0.0235 0.0365
Schistosoma mansoni alpha-glucosidase 0.0318 0.2053 0.2029
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0235 0.0231
Leishmania major short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Plasmodium falciparum steroid dehydrogenase, putative 0.0047 0.0086 0.0027
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Mycobacterium tuberculosis Probable dehydrogenase 0.0047 0.0086 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans epoxide hydrolase EphA 0.0395 0.2606 0.8455
Entamoeba histolytica short chain dehydrogenase family protein 0.0047 0.0086 0.1802
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0403 0.2669 0.8661
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0257 0.161 0.1584
Echinococcus multilocularis glutamate receptor 2 0.0067 0.0231 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus granulosus metabotropic glutamate receptor 2 0.0067 0.0231 0.0226
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Plasmodium vivax glutathione reductase, putative 0.0052 0.0119 0.0134
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0047 0.0086 0.0049
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Echinococcus granulosus hypothetical protein 0.0047 0.0086 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0447 0.2987 0.4644
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Echinococcus granulosus Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0335 0.2172 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0131 0.0694 0.4527
Echinococcus granulosus jumonji domain containing 1A 0.0084 0.0353 0.0364
Mycobacterium ulcerans oxidoreductase 0.0047 0.0086 0.0159
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0211 0.1275 0.1431
Echinococcus multilocularis caspase 3 0.0785 0.5438 0.6096
Schistosoma mansoni hypothetical protein 0.0445 0.297 0.2949
Leishmania major GTP-binding protein, putative 0.0046 0.0078 0.0126
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Echinococcus multilocularis lysosomal alpha glucosidase 0.037 0.2426 0.2701
Brugia malayi Importin beta-1 subunit 0.0062 0.0197 0.0306
Plasmodium falciparum importin beta, putative 0.0062 0.0197 0.0381
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Onchocerca volvulus 0.0047 0.0086 0.0049
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Brugia malayi hypothetical protein 0.0039 0.003 0.0047
Onchocerca volvulus 0.0047 0.0086 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0447 0.2987 0.3458
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0069 0.0243 0.0647
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0478 0.3208 0.3187
Echinococcus multilocularis steroid dehydrogenase 0.0047 0.0086 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0468 0.0728
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0211 0.1275 0.1403
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Trichomonas vaginalis steroid dehydrogenase, putative 0.0047 0.0086 0.0152
Schistosoma mansoni tyrosine kinase 0.0062 0.0192 0.0163
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.046 0.3076 0.3434
Schistosoma mansoni glutamate receptor NMDA 0.0198 0.1177 0.1151
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Echinococcus multilocularis beta tubulin 0.0049 0.0102 0.0082
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.019 0.1125 0.3578
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.034 0.0529
Echinococcus granulosus caspase 3 0.0785 0.5438 0.6096
Brugia malayi ecdysone receptor 0.0211 0.1275 0.1981
Chlamydia trachomatis glutamine binding protein 0.0335 0.2172 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Plasmodium falciparum tubulin beta chain 0.0049 0.0102 0.0079
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.037 0.2426 0.2799
Loa Loa (eye worm) STAT protein 0.0153 0.0851 0.0954
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0246 0.1525 0.4693
Brugia malayi nuclear hormone receptor 0.0447 0.2987 0.4644
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0047 0.0086 0.0063
Echinococcus granulosus JmjC domain containing protein 4 0.0084 0.0353 0.0364
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Brugia malayi Cell death protein 3 precursor 0.0923 0.6433 1
Echinococcus granulosus glutamate NMDA receptor subunit 0.0131 0.0692 0.0746
Loa Loa (eye worm) glutamate receptor 2 0.0131 0.0692 0.0767
Toxoplasma gondii thioredoxin reductase 0.0052 0.0119 0.0258
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0119 0.0101
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Leishmania major short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Brugia malayi Glutamate receptor 2 precursor 0.0131 0.0692 0.1076
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis epidermal growth factor receptor 0.0103 0.0492 0.0521
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Trypanosoma brucei trypanothione reductase 0.0052 0.0119 0.0258
Trypanosoma cruzi extracellular receptor, putative 0.0067 0.0231 0.0609
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0358 0.0898
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Brugia malayi nuclear hormone receptor family member nhr-6 0.0211 0.1275 0.1981
Leishmania major pteridine reductase 1 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Brugia malayi N-terminal motif family protein 0.0193 0.1141 0.1773
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.029 0.1848 0.2122
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0047 0.0086 0.0063
Brugia malayi Glycosyl hydrolases family 31 protein 0.037 0.2426 0.3771
Echinococcus multilocularis beta LACTamase domain containing family member 0.019 0.1125 0.1234
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0047 0.0086 0.0152
Brugia malayi hydrolase, alpha/beta fold family protein 0.0615 0.4204 0.6536
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0119 0.0101
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0403 0.2669 0.3113
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0236 0.1458 0.161
Schistosoma mansoni thyroid hormone receptor 0.0447 0.2987 0.2966
Schistosoma mansoni tyrosine kinase 0.0191 0.1129 0.1102
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Echinococcus multilocularis peptidase Clp (S14 family) 0.0161 0.0912 0.0994
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Onchocerca volvulus 0.0047 0.0086 0.0049
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0047 0.0086 0.0092
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0118 0.0599 0.3899
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0062 0.0192 0.0183
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0131 0.0692 0.0746
Loa Loa (eye worm) tubulin beta-1 chain 0.0049 0.0102 0.0076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.046 0.3076 0.9584
Leishmania major hypothetical protein, conserved 0.0084 0.0353 0.0994
Schistosoma mansoni coup transcription factor 0.0447 0.2987 0.2966
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Schistosoma mansoni nuclear hormone receptor 0.0211 0.1275 0.1248
Loa Loa (eye worm) tubulin beta-2A chain 0.0049 0.0102 0.0076
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Brugia malayi hypothetical protein 0.0236 0.1458 0.2267
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0197 0.0187
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.046 0.3076 0.3589
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0047 0.0086 0.0152
Entamoeba histolytica hypothetical protein 0.0047 0.0086 0.1802
Brugia malayi Protein kinase domain containing protein 0.0062 0.0192 0.0299
Trichomonas vaginalis esterase, putative 0.019 0.1125 0.3429
Onchocerca volvulus Bile acid receptor homolog 0.0447 0.2987 0.3422
Echinococcus granulosus apoptotic protease activating factor 1 0.0445 0.297 0.3315
Echinococcus multilocularis aryl hydrocarbon receptor 0.0041 0.0043 0.0015
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Brugia malayi hypothetical protein 0.0047 0.0086 0.0133
Echinococcus multilocularis receptor type guanylyl cyclase 0.0069 0.0245 0.0243
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0447 0.2987 0.3334
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0447 0.2987 0.3334
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0447 0.2987 0.3334
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0085 0.0358 0.2315
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0211 0.1275 0.1248
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus granulosus receptor type guanylyl cyclase 0.0069 0.0245 0.0243
Loa Loa (eye worm) nuclear receptor NHR-67 0.0211 0.1275 0.145
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0047 0.0086 0.0152
Toxoplasma gondii oxidoreductase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Brugia malayi Metabotropic glutamate receptor precursor. 0.0067 0.0231 0.0358
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni aldehyde dehydrogenase 0.046 0.3076 0.3055
Echinococcus multilocularis epidermal growth factor receptor 0.0191 0.1129 0.1239
Brugia malayi Thioredoxin reductase 0.0052 0.0119 0.0186
Schistosoma mansoni retinoic acid receptor RXR 0.0447 0.2987 0.2966
Brugia malayi beta-lactamase family protein 0.019 0.1125 0.1748
Mycobacterium ulcerans short chain dehydrogenase 0.038 0.2502 0.811
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0447 0.2987 0.3458
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Mycobacterium tuberculosis Possible oxidoreductase 0.0047 0.0086 0.0092
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.024 0.0372
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0335 0.2172 1
Trichomonas vaginalis adenylate cyclase, putative 0.0041 0.0043 0.0018
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0047 0.0086 0.0152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.1199 0.3664
Loa Loa (eye worm) hypothetical protein 0.0054 0.014 0.012
Schistosoma mansoni tyrosine kinase 0.0069 0.0245 0.0216
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0211 0.1275 0.1403
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0119 0.0258
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Leishmania major importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.1199 0.3664
Onchocerca volvulus 0.0447 0.2987 0.3422
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0235 0.0231
Onchocerca volvulus 0.0047 0.0086 0.0049
Schistosoma mansoni glutamate receptor NMDA 0.0131 0.0692 0.0664
Mycobacterium ulcerans hypothetical protein 0.019 0.1125 0.3578
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Echinococcus granulosus oxidoreductase 0.0047 0.0086 0.0063
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Brugia malayi ecdysteroid receptor 0.0447 0.2987 0.4644
Echinococcus multilocularis geminin 0.054 0.3657 0.4089
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0041 0.0043 0.0018
Brugia malayi jmjC domain containing protein 0.0314 0.2023 0.3145
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0478 0.3208 0.3716
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0447 0.2987 0.4644
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans dehydrogenase 0.0047 0.0086 0.0159
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Onchocerca volvulus Protein ultraspiracle homolog 0.0447 0.2987 0.3422
Trypanosoma brucei Metacaspase-4 0.0478 0.3208 1
Schistosoma mansoni jumonji domain containing protein 0.0084 0.0353 0.0324
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.014 0.0199
Echinococcus granulosus lysine specific demethylase 6a 0.0084 0.0353 0.0364
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Mycobacterium ulcerans short chain dehydrogenase 0.0058 0.0164 0.0417
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0198 0.1177 0.1294
Echinococcus multilocularis JmjC domain containing protein 4 0.0084 0.0353 0.0364
Echinococcus granulosus FTZ F1 alpha 0.0447 0.2987 0.3334
Onchocerca volvulus 0.0445 0.297 0.3401
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0047 0.0086 0.0152
Brugia malayi Guanylyl cyclase protein 23 0.0069 0.0245 0.0381
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.034 0.0954
Brugia malayi bHLH-PAS transcription factor 0.0117 0.0594 0.0924
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0047 0.0086 0.0152
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Toxoplasma gondii beta-1 tubulin, putative 0.0049 0.0102 0.0204
Trypanosoma brucei metacaspase MCA3 0.0478 0.3208 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0084 0.0353 0.0364
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0197 0.0502
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0211 0.1275 0.1403
Trypanosoma cruzi cruzipain precursor, putative 0.0075 0.029 0.0796
Plasmodium vivax JmjC domain containing protein 0.0084 0.0353 0.0879
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Echinococcus granulosus snurportin 1 0.0665 0.4566 0.5113
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0047 0.0086 0.0092
Entamoeba histolytica hypothetical protein 0.0067 0.0231 0.6471
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Plasmodium falciparum JmjC domain-containing protein, putative 0.0084 0.0353 0.0879
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0047 0.0086 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis lysine specific demethylase 6a 0.0084 0.0353 0.0364
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.014 0.0323
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Leishmania major oxidoreductase-like protein 0.0047 0.0086 0.0152
Echinococcus multilocularis muscleblind protein 1 0.067 0.4602 0.5154
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.034 0.0355
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0062 0.0192 0.0183
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0403 0.2669 0.83
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1216 0.8558 1
Brugia malayi beta-lactamase family protein 0.019 0.1125 0.1748
Schistosoma mansoni jumonji domain containing protein 0.0314 0.2023 0.1999
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Toxoplasma gondii ABC1 family protein 0.019 0.1125 0.3429
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Giardia lamblia Short-chain dehydrogenase, putative 0.0047 0.0086 0.3356
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0038 0.0245
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.034 0.0954
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Giardia lamblia Hypothetical protein 0.0047 0.0086 0.3356
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0447 0.2987 0.4644
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0236 0.1454 0.1605
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0665 0.4566 0.5308
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Echinococcus granulosus tar DNA binding protein 0.0068 0.0235 0.0231
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Brugia malayi Glutamate receptor 1 precursor 0.0131 0.0692 0.1076
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Echinococcus multilocularis tubulin beta 1 chain 0.0049 0.0102 0.0082
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Loa Loa (eye worm) tubulin beta-4 chain 0.0049 0.0102 0.0076
Schistosoma mansoni zinc finger protein 0.0211 0.1275 0.1248
Schistosoma mansoni RAR-like nuclear receptor 0.0447 0.2987 0.2966
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Onchocerca volvulus 0.0211 0.1275 0.1431
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0067 0.0231 0.0226
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0447 0.2987 0.2966
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0236 0.1454 0.1605
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0047 0.0086 0.0063
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0211 0.1275 0.1403
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Echinococcus granulosus tyrosine kinase 0.0069 0.0245 0.0243
Echinococcus granulosus geminin 0.054 0.3657 0.4089
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0041 0.0043 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Mycobacterium tuberculosis Probable hydrolase 0.019 0.1125 0.1307
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0047 0.0086 0.0049
Brugia malayi Retinol dehydrogenase 12 0.0047 0.0086 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0118 0.0599 0.0692
Schistosoma mansoni ATP-binding cassette transporter 0.0131 0.0692 0.0664
Echinococcus granulosus tubulin beta 4A class IVa 0.0049 0.0102 0.0082
Entamoeba histolytica hypothetical protein, conserved 0.0047 0.0086 0.1802
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0131 0.0692 0.0746
Schistosoma mansoni nuclear receptor nhr-48 0.0211 0.1275 0.1248
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0118 0.0599 0.0692
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Onchocerca volvulus Cell death protein 3 homolog 0.0923 0.6433 0.7426
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Brugia malayi STAT protein, DNA binding domain containing protein 0.0153 0.0851 0.1324
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Brugia malayi Receptor family ligand binding region containing protein 0.0069 0.0245 0.0381
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0447 0.2987 0.3334
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Brugia malayi nuclear receptor RXR 0.0211 0.1275 0.1981
Trypanosoma brucei metacaspase 5, putative 0.0478 0.3208 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0335 0.2172 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Trypanosoma cruzi short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0246 0.1525 0.4693
Plasmodium vivax steroid dehydrogenase, putative 0.0047 0.0086 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma cruzi metacaspase 5, putative 0.0478 0.3208 1
Plasmodium falciparum metacaspase-like protein 0.0478 0.3208 1
Mycobacterium ulcerans putative regulatory protein 0.0117 0.0594 0.1832
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni inositol monophosphatase 0.004 0.0038 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0447 0.2987 0.4644
Loa Loa (eye worm) RNA binding protein 0.0068 0.0235 0.0231
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis glutamate receptor 2 0.0198 0.1177 0.1294
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Plasmodium falciparum thioredoxin reductase 0.0052 0.0119 0.0134
Mycobacterium leprae Probable oxidoreductase 0.0047 0.0086 0.052
Mycobacterium ulcerans carveol-like dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis tubulin subunit beta 0.0049 0.0102 0.0082
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni caspase-7 (C14 family) 0.0923 0.6433 0.6422
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0314 0.2023 0.2247
Schistosoma mansoni ran 0.0046 0.0078 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0157 0.0884 0.0857
Loa Loa (eye worm) jmjC domain-containing protein 0.0314 0.2023 0.2327
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Onchocerca volvulus 0.0047 0.0086 0.0049
Onchocerca volvulus 0.019 0.1125 0.1257
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0157 0.0884 0.0857
Brugia malayi TAR-binding protein 0.0068 0.0235 0.0365
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.034 0.0954
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0197 0.0502
Brugia malayi Dehydrogenases, short chain protein 30 0.0047 0.0086 0.0133
Leishmania major hypothetical protein, conserved 0.0054 0.014 0.0323
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0047 0.0086 0.052
Schistosoma mansoni hypothetical protein 0.0665 0.4566 0.4549
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Onchocerca volvulus 0.0047 0.0086 0.0049
Onchocerca volvulus 0.0211 0.1275 0.1431
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0131 0.0692 0.0746
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Mycobacterium ulcerans lipase LipD 0.019 0.1125 0.3578
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0468 0.0728
Brugia malayi Tubulin beta-1 chain 0.0049 0.0102 0.0159
Onchocerca volvulus 0.0047 0.0086 0.0049
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0161 0.0912 0.1058
Toxoplasma gondii aldehyde dehydrogenase 0.046 0.3076 0.9584
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.034 0.0954
Mycobacterium leprae Probable lipase LipE 0.019 0.1125 0.7361
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0161 0.0912 0.5961
Mycobacterium tuberculosis Probable lipase LipD 0.019 0.1125 0.1307
Onchocerca volvulus 0.0214 0.1296 0.1455
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0447 0.2987 0.3334
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Echinococcus multilocularis tyrosine kinase 0.0069 0.0245 0.0243
Onchocerca volvulus Sepiapterin reductase homolog 0.0047 0.0086 0.0049
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0047 0.0086 0.0056
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0067 0.0231 0.0226
Brugia malayi Nuclear hormone receptor E75 0.0211 0.1275 0.1981
Brugia malayi steroid hormone receptor 0.0447 0.2987 0.4644
Schistosoma mansoni retinal dehydrogenase 0.0047 0.0086 0.0056
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypoxia-induced factor 1 0.049 0.3295 0.3819
Loa Loa (eye worm) hydrolase 0.1218 0.8569 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Plasmodium vivax tubulin beta chain, putative 0.0049 0.0102 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0447 0.2987 0.4644
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0084 0.0353 0.0994
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0078 0.0126
Brugia malayi Muscleblind-like protein 0.067 0.4602 0.7154
Echinococcus multilocularis FTZ F1 alpha 0.0447 0.2987 0.3334
Mycobacterium tuberculosis Probable dehydrogenase 0.0118 0.0599 0.0692
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6961
Trypanosoma cruzi metacaspase 5, putative 0.0478 0.3208 1
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Trichomonas vaginalis tubulin alpha chain, putative 0.0049 0.0102 0.0204
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Toxoplasma gondii melibiase subfamily protein 0.0236 0.1454 0.4467
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0102 0.0076
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0047 0.0086 0.0325
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Schistosoma mansoni hypothetical protein 0.054 0.3657 0.3638
Onchocerca volvulus 0.0067 0.0231 0.0218
Echinococcus granulosus nmda type glutamate receptor 0.0466 0.3119 0.3483
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0038 0.0009
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0058 0.0164 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.1125 0.3429
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0478 0.3208 0.4987
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0447 0.2987 0.3458
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0197 0.0502
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Possible oxidoreductase 0.0047 0.0086 0.0092
Echinococcus multilocularis snurportin 1 0.0665 0.4566 0.5113
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trichomonas vaginalis ran, putative 0.0046 0.0078 0.0126
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0211 0.1275 0.1981
Echinococcus multilocularis steroid dehydrogenase 0.0047 0.0086 0.0063
Schistosoma mansoni single-minded 0.0158 0.0892 0.0865
Loa Loa (eye worm) hypothetical protein 0.067 0.4602 0.535
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0173 0.0428
Schistosoma mansoni caspase-3 (C14 family) 0.1263 0.89 0.8897
Brugia malayi MH2 domain containing protein 0.0398 0.2629 0.4087
Echinococcus multilocularis NMDA receptor 0.0131 0.0692 0.0746
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Echinococcus granulosus thyroid hormone receptor alpha 0.0211 0.1275 0.1403
Echinococcus multilocularis muscleblind protein 0.067 0.4602 0.5154
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0246 0.1525 0.1686
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus granulosus tyrosine protein kinase shark 0.0217 0.1319 0.1454
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni ran 0.0046 0.0078 0.0048
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.034 0.0954
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0403 0.2669 0.2975
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.034 0.035
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0047 0.0086 0.0152
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0047 0.0086 0.0063
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0067 0.0231 0.0226
Loa Loa (eye worm) nuclear hormone receptor 0.0211 0.1275 0.145
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Loa Loa (eye worm) hypothetical protein 0.0246 0.1525 0.1744
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0118 0.0599 0.0692
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Loa Loa (eye worm) tubulin beta chain 0.0049 0.0102 0.0076
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0084 0.0353 0.0324
Schistosoma mansoni steroid hormone receptor ad4bp 0.0447 0.2987 0.2966
Echinococcus multilocularis 0.0059 0.0171 0.0159
Brugia malayi Nuclear hormone receptor-like 1 0.0236 0.1458 0.2267
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0047 0.0086 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) glutamate receptor 0.0067 0.0231 0.0226

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 159 nM Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins by fluorescence analysis ChEMBL. 22522007
IC50 (binding) = 0.05 uM Inhibitory concentration against mouse soluble epoxide hydrolase (sEH) at 0.12 uM ChEMBL. 15887969
IC50 (binding) = 0.05 uM Inhibitory concentration against mouse soluble epoxide hydrolase (sEH) at 0.12 uM ChEMBL. 15887969
IC50 (binding) = 5 uM Inhibitory concentration against human soluble epoxide hydrolase (sEH) at 0.24 uM ChEMBL. 15887969
IC50 (binding) = 5 uM Inhibitory concentration against human soluble epoxide hydrolase (sEH) at 0.24 uM ChEMBL. 15887969
logP (ADMET) = 5.52 Partition coefficient (logP) ChEMBL. 15887969
MIC (functional) = 4.17 ug ml-1 Antimycobacterial activity against Mycobacterium tuberculosis H37Ra ChEMBL. 22522007
S = 0.42 ug ml-1 Solubility of the compound in sodium phosphate buffer 0.1M, pH 7.4 at 25 +/-1.5 degree C ChEMBL. 15887969

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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