Detailed information for compound 451551

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 363.193 | Formula: C16H14INO
  • H donors: 1 H acceptors: 1 LogP: 4.32 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNc1ccc(cc1)/C=C/C(=O)c1ccc(cc1)I
  • InChi: 1S/C16H14INO/c1-18-15-9-2-12(3-10-15)4-11-16(19)13-5-7-14(17)8-6-13/h2-11,18H,1H3/b11-4+
  • InChiKey: HDESUHCGHCYLHU-NYYWCZLTSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis somatostatin receptor 0.0328 0.1477 0.1477
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0129 0.0129
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0023 0.0023
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.0037 0.0364
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0056 0.0193 0.0402
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0343 0.0794
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0698 0.0698
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Onchocerca volvulus 0.0328 0.1477 0.6337
Loa Loa (eye worm) glutathione reductase 0.0148 0.0626 0.0626
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0056 0.0193 0.1873
Schistosoma mansoni cytochrome P450 0.0056 0.0193 0.0193
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0032 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0231 0.0231
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0032 0.0032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0298 0.0298
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.017 0.1656
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Echinococcus granulosus orexin receptor type 2 0.0328 0.1477 0.1477
Leishmania major potassium channel subunit-like protein 0.0023 0.0037 0.0364
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Trypanosoma brucei glucosidase, putative 0.0036 0.0099 0.0967
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0023 0.0023
Brugia malayi Nuclear hormone receptor E75 0.002 0.0023 0.0031
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.017 0.1071
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0056 0.0193 0.0402
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0023 0.0037 0.0037
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.1029 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.014 0.0574
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0045 0.014 0.014
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0032 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0129 0.0172
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0204 0.1983
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0056 0.0193 0.1873
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1029 0.4423
Onchocerca volvulus 0.0328 0.1477 0.6337
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0204 0.1983
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0056 0.0193 0.0402
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0032 0.0043
Plasmodium falciparum glutathione reductase 0.0148 0.0626 0.1527
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0129 0.0129
Loa Loa (eye worm) beta-tubulin 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0056 0.0193 0.0402
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0038 0.0001
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0032 0.0032
Mycobacterium tuberculosis Probable oxidoreductase 0.0374 0.1696 0.4297
Schistosoma mansoni neuropeptide F-like receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis set domain proteins, putative 0.0508 0.2326 1
Toxoplasma gondii beta-1 tubulin, putative 0.0023 0.0036 0.0468
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.017 0.2277
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0099 0.0428
Loa Loa (eye worm) tubulin beta-2A chain 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0079 0.0304 0.0304
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0023 0.0023
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0064 0.0231 0.0163
Echinococcus multilocularis neuropeptide Y receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0007 0.0007
Plasmodium falciparum thioredoxin reductase 0.0148 0.0626 0.1527
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0129 0.0129
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0328 0.1477 0.1477
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0006 0.0006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0129 0.1249
Echinococcus multilocularis voltage dependent calcium channel 0.0079 0.0304 0.0304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0056 0.0239
Onchocerca volvulus 0.0328 0.1477 0.6337
Toxoplasma gondii 6-phosphofructokinase 0.0063 0.0226 0.3538
Loa Loa (eye worm) hypothetical protein 0.003 0.0072 0.0072
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0328 0.1477 0.1477
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0129 0.0129
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0035 0.0035
Echinococcus granulosus 6 phosphofructokinase 0.0233 0.1029 0.1029
Echinococcus multilocularis beta tubulin 0.0023 0.0036 0.0036
Brugia malayi PXA domain containing protein 0.0022 0.0032 0.0043
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0328 0.1477 0.1477
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0129 0.0172
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0298 0.128
Brugia malayi 6-phosphofructokinase 0.0233 0.1029 0.1371
Schistosoma mansoni zinc finger protein 0.002 0.0023 0.0023
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Brugia malayi Serotonin receptor 0.0788 0.3648 0.4861
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1029 0.7928
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis small conductance calcium activated potassium 0.0023 0.0037 0.0037
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0186
Echinococcus granulosus microtubule associated protein 2 0.137 0.6397 0.6397
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0129 0.0129
Echinococcus multilocularis 0.0056 0.0193 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Trichomonas vaginalis tubulin alpha chain, putative 0.0023 0.0036 0.0155
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0204 0.1983
Leishmania major cytochrome p450-like protein 0.0056 0.0193 0.1873
Brugia malayi Thioredoxin reductase 0.0148 0.0626 0.0834
Brugia malayi neuropeptide F receptor 0.0328 0.1477 0.1967
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0141 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0056 0.0193 0.0402
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0005
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0482 0.0482
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0129 0.0172
Brugia malayi MH2 domain containing protein 0.0119 0.0491 0.0654
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0063 0.0226 0.1515
Echinococcus granulosus g-protein coupled receptor 0.0328 0.1477 0.1477
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0056 0.0193 0.0193
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0032 0.0032
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0377 0.1709 0.1709
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0129 0.053
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0005 0.0007
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0056 0.0193 0.0402
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.1029 0.1029
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.0037 0.0037
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0079 0.0304 0.0405
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.0036 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.017 0.1656
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0204 0.0204
Trypanosoma cruzi cytochrome P450, putative 0.0184 0.0799 0.7763
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0048 0.0465
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0698 0.093
Echinococcus multilocularis chromobox protein 1 0.008 0.0305 0.0305
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0129 0.0129
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0374 0.1696 0.4297
Echinococcus granulosus twik family of potassium channels 0.0023 0.0037 0.0037
Echinococcus multilocularis neuropeptide receptor 0.0328 0.1477 0.1477
Toxoplasma gondii endonuclease IV APN 0.0088 0.0343 0.5424
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Onchocerca volvulus 0.0328 0.1477 0.6337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.362
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Onchocerca volvulus 0.0031 0.0074 0.0293
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0129 0.1249
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0035 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.0328 0.1477 0.1477
Trypanosoma cruzi ion transport protein, putative 0.0023 0.0037 0.0364
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.0106 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0877
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0129 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0129 0.0172
Brugia malayi Heterochromatin protein 1 0.008 0.0305 0.0406
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0328 0.1477 0.1477
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0141 0.137
Brugia malayi hypothetical protein 0.0022 0.0035 0.0046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0098 0.042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0023 0.0037 0.005
Brugia malayi MAP kinase sur-1 0.0058 0.0204 0.0272
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0377 0.1709 0.1709
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0099 0.0967
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0328 0.1477 0.1477
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0056 0.0193 0.0402
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.0025 0.0048 0.0064
Onchocerca volvulus 0.0023 0.0037 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0023 0.0023
Echinococcus multilocularis sex peptide receptor 0.0328 0.1477 0.1477
Brugia malayi Death domain containing protein 0.0016 0.0006 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0056 0.0193 0.0402
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0144 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Plasmodium vivax potassium channel, putative 0.0023 0.0037 0.0023
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0156 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0187
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0056 0.0193 0.0402
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.03 0.1291
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.0037 0.0037
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0056 0.0193 0.0402
Loa Loa (eye worm) hypothetical protein 0.2133 1 1
Onchocerca volvulus 0.0328 0.1477 0.6337
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.0231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0328 0.1477 0.1477
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0204 0.3182
Echinococcus granulosus g protein coupled receptor 0.0328 0.1477 0.1477
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0079 0.03 0.0348
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0023 0.0023
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.017 0.0344
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0231 0.0231
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.017 0.017
Echinococcus granulosus neuropeptide receptor 0.0328 0.1477 0.1477
Brugia malayi hypothetical protein 0.0022 0.0032 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0071 0.0306
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0074 0.0074
Leishmania major cytochrome p450-like protein 0.0184 0.0799 0.7763
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0056 0.0193 0.0402
Brugia malayi chromobox protein homolog 3 0.0045 0.014 0.0186
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.084 0.3897 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0099 0.0428
Toxoplasma gondii ion channel protein 0.0023 0.0037 0.049
Schistosoma mansoni opsin-like receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.017 0.0732
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0094
Trypanosoma cruzi cytochrome P450, putative 0.0184 0.0799 0.7763
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0023 0.0037 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0231 0.0231
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0032 0.0032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0099 0.0428
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0087 0.1285
Plasmodium falciparum potassium channel 0.0023 0.0037 0.0003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0328 0.1477 0.6337
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.084 0.3897 1
Echinococcus granulosus neuropeptide Y receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Onchocerca volvulus 0.0328 0.1477 0.6337
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0023 0.0037 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) neuropeptide F receptor 0.0328 0.1477 0.1477
Echinococcus granulosus voltage dependent calcium channel 0.0079 0.0304 0.0304
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0032 0.0032
Schistosoma mansoni biogenic amine receptor 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0023 0.0037 0.0134
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0129 0.1249
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0141 0.0188
Echinococcus multilocularis g protein coupled receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0184 0.0799 0.0799
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0057 0.02 0.086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0129 0.0129
Loa Loa (eye worm) tubulin beta-1 chain 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus multilocularis orexin receptor type 2 0.0328 0.1477 0.1477
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0038 0.0001
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0099 0.0967
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0328 0.1477 0.1477
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1604 0.7505 0.7505
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi hypothetical protein 0.0035 0.0096 0.0128
Schistosoma mansoni neuropeptide receptor 0.0328 0.1477 0.1477
Onchocerca volvulus Neuropeptide F receptor homolog 0.0328 0.1477 0.6337
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0056 0.0193 0.0402
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0035 0.0035
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0023 0.0023
Echinococcus granulosus sex peptide receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0491 0.0491
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0328 0.1477 0.1967
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0056 0.0193 0.0402
Loa Loa (eye worm) phosphofructokinase 0.0233 0.1029 0.1029
Echinococcus granulosus neuropeptides capa receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus granulosus alpha 1A adrenergic receptor 0.0328 0.1477 0.1477
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0129 0.0172
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0187
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0129 0.0129
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0056 0.0193 0.1873
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.1029 0.1029
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0186
Echinococcus multilocularis neuropeptide Y receptor 0.0328 0.1477 0.1477
Brugia malayi nuclear receptor NHR-88 0.0042 0.0129 0.0172
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0363 0.0363
Echinococcus multilocularis voltage dependent calcium channel 0.0079 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0128 0.0535 0.0535
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0337 0.1518 0.3837
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0069 0.1008
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0032 0.0032
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0141 0.0606
Echinococcus multilocularis allatostatin A receptor 0.0328 0.1477 0.1477
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0144 0.0609 0.0609
Echinococcus multilocularis neuropeptide s receptor 0.0328 0.1477 0.1477
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0056 0.0193 0.0402
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Echinococcus granulosus potassium channel subfamily K 0.0023 0.0037 0.0037
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0099 0.1493
Onchocerca volvulus 0.0094 0.0374 0.1583
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0233 0.1029 0.2303
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0056 0.0193 0.0402
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1604 0.7505 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0129 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1029 0.4423
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.0036 0.0155
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0482 0.0482
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0377 0.1709 0.2277
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0069 0.0069
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.017 0.2638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0234
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0048 0.0199
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0129 0.1249
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0067 0.0967
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0363 0.0363
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0023 0.0031
Schistosoma mansoni amine GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Plasmodium falciparum flap endonuclease 1 0.003 0.0069 0.0086
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0023 0.0036 0.0036
Plasmodium vivax potassium channel, putative 0.0023 0.0037 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0099 0.0428
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0064 0.0231 0.0231
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.0036 0.0036
Brugia malayi hypothetical protein 0.0122 0.0503 0.0671
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0184 0.0799 0.1972
Echinococcus granulosus twik family of potassium channels 0.0023 0.0037 0.0037
Echinococcus multilocularis thioredoxin glutathione reductase 0.0148 0.0626 0.0626
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0023 0.0031
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.0036 0.0036
Loa Loa (eye worm) TYRA-2 protein 0.0328 0.1477 0.1477
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0328 0.1477 0.1477
Echinococcus multilocularis musashi 0.0031 0.0074 0.0074
Brugia malayi G-protein coupled receptor 0.0328 0.1477 0.1967
Loa Loa (eye worm) hypothetical protein 0.0317 0.1426 0.1426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0187
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0079 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Toxoplasma gondii beta-tubulin, putative 0.0023 0.0036 0.0468
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0006 0.0006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0035 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0141 0.0606
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0023 0.0031
Loa Loa (eye worm) G-protein coupled receptor 0.0328 0.1477 0.1477
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0141 0.137
Brugia malayi Flap endonuclease-1 0.003 0.0069 0.0093
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0038 0.0135
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0032 0.0032
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni neuropeptide receptor 0.0328 0.1477 0.1477
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.017 0.2277
Loa Loa (eye worm) norepinephrine transporter 0.0377 0.1709 0.1709
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0079 0.0304 0.0304
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.084 0.3897 1
Echinococcus multilocularis chromobox protein 1 0.008 0.0305 0.0305
Echinococcus granulosus Ankyrin 0.0017 0.0007 0.0007
Onchocerca volvulus 0.0023 0.0037 0.0134
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0056 0.0193 0.0402
Echinococcus multilocularis serotonin receptor 0.2133 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0141 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0129 0.0172
Brugia malayi Melatonin receptor type 1A 0.0328 0.1477 0.1967
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0156 0.067
Brugia malayi phosphofructokinase 0.0233 0.1029 0.1371
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Onchocerca volvulus 0.0035 0.0094 0.0378
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.1029 0.1029
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0328 0.1477 0.1967
Echinococcus granulosus neuropeptide FF receptor 2 0.0328 0.1477 0.1477
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0023 0.0023
Loa Loa (eye worm) BEN-1 protein 0.0023 0.0036 0.0036
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Schistosoma mansoni inositol monophosphatase 0.0079 0.03 0.03
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.1029 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0024 0.004 0.004
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0056 0.0193 0.0402
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0048 0.0465
Brugia malayi AKH receptor 0.0328 0.1477 0.1967
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0129 0.053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0129 0.0737
Plasmodium vivax SET domain protein, putative 0.0064 0.0231 0.3304
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0032 0.0043
Schistosoma mansoni hypothetical protein 0.0023 0.0037 0.0037
Onchocerca volvulus 0.0328 0.1477 0.6337
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0023 0.0023
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0698 0.0698
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0032 0.0032
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0023 0.0037 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0099 0.0428
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0328 0.1477 0.1477
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0129 0.0129
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0204 0.0204
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.03 0.2918
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0064 0.0231 0.0231
Schistosoma mansoni inositol monophosphatase 0.0079 0.03 0.03
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0129 0.0129
Echinococcus granulosus thioredoxin glutathione reductase 0.0148 0.0626 0.0626
Brugia malayi Protein kinase domain containing protein 0.0017 0.0009 0.0012
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0079 0.0304 0.0304
Echinococcus granulosus g protein coupled receptor 0.0328 0.1477 0.1477
Trypanosoma brucei trypanothione reductase 0.0148 0.0626 0.6082
Echinococcus multilocularis g protein coupled receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Schistosoma mansoni amine GPCR 0.0659 0.304 0.304
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0032 0.0043
Echinococcus granulosus beta tubulin 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0337 0.1518 0.3837
Echinococcus multilocularis Ankyrin 0.0017 0.0007 0.0007
Echinococcus granulosus tubulin beta 4A class IVa 0.0023 0.0036 0.0036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0037 0.0161
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0056 0.0193 0.0402
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Mycobacterium ulcerans hypothetical protein 0.0023 0.0038 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0482 0.0482
Schistosoma mansoni lamin 0.0031 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Onchocerca volvulus 0.0064 0.0231 0.0968
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.1029 0.1029
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0129 0.0129
Schistosoma mansoni nuclear hormone receptor 0.002 0.0023 0.0023
Brugia malayi tailless protein 0.002 0.0023 0.0031
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0023 0.0031
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0129 0.0765
Toxoplasma gondii thioredoxin reductase 0.0148 0.0626 1
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.017 0.1656
Echinococcus multilocularis serotonin receptor 0.2133 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.017 0.0344
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0129 0.0129
Brugia malayi nuclear receptor NHR-67 0.002 0.0023 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Loa Loa (eye worm) hypothetical protein 0.0035 0.0095 0.0095
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0204 0.1983
Onchocerca volvulus 0.0328 0.1477 0.6337
Brugia malayi Pre-SET motif family protein 0.0064 0.0231 0.0308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Trichomonas vaginalis tubulin gamma chain, putative 0.0023 0.0036 0.0155
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0118 0.0118
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.017 0.017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.017 0.0227
Brugia malayi nuclear receptor RXR 0.002 0.0023 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0048 0.003
Loa Loa (eye worm) TWK-7 protein 0.0023 0.0037 0.0037
Schistosoma mansoni flap endonuclease-1 0.0027 0.0056 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0056 0.0193 0.0402
Brugia malayi Dopamine receptor protein 2 0.0328 0.1477 0.1967
Leishmania major trypanothione reductase 0.0148 0.0626 0.6082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0328 0.1477 0.1477
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.03 0.2918
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0056 0.0193 0.0402
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0328 0.1477 0.6337
Mycobacterium ulcerans epimerase 0.0023 0.0038 0.0001
Toxoplasma gondii ion channel protein 0.0023 0.0037 0.049
Loa Loa (eye worm) hypothetical protein 0.0377 0.1709 0.1709
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0226 0.0149
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0029 0.0284
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0129 0.0129
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0141 0.0864
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0134 0.0134
Brugia malayi glutathione reductase 0.0148 0.0626 0.0834
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0099 0.0428
Echinococcus granulosus neuropeptide receptor 0.0328 0.1477 0.1477
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0023 0.0037 0.005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0129 0.0172
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0023 0.0023
Mycobacterium leprae Conserved hypothetical protein 0.0056 0.0193 0.0402
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0261 0.0579
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) serotonin transporter b 0.0377 0.1709 0.1709
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.0036 0.0155
Brugia malayi PXA domain containing protein 0.0022 0.0032 0.0043
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0226 0.0492
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Echinococcus granulosus voltage dependent calcium channel 0.0029 0.0067 0.0067
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.006 0.026
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0099 0.0534
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Giardia lamblia GTOR 0.0045 0.0141 0.0837
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0337 0.1518 0.3837
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0056 0.0193 0.0402
Brugia malayi putative neuropeptide receptor 0.0328 0.1477 0.1967
Plasmodium falciparum amino acid transporter, putative 0.0064 0.0231 0.0505
Mycobacterium leprae putative cytochrome p450 0.0056 0.0193 0.0402
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0056 0.0193 0.0402
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0032 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0056 0.0193 0.0402
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Brugia malayi hypothetical protein 0.0064 0.0231 0.0308
Echinococcus granulosus tubulin beta 1 chain 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0328 0.1477 0.6337
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0056 0.0193 0.0402
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0328 0.1477 0.1477
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0032 0.0032
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0129 0.0129
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0129 0.0129
Echinococcus granulosus allatostatin A receptor 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0328 0.1477 0.6337
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0035 0.0035
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0098 0.095
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0048 0.003
Brugia malayi hypothetical protein 0.0022 0.0032 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0098 0.042
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0079 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus granulosus 7TM GPCR rhodopsin 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0023 0.0037 0.0134
Onchocerca volvulus 0.0023 0.0037 0.0134
Brugia malayi Uncoordinated protein 44 0.0016 0.0006 0.0009
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.0308
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.004 0.004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0079 0.03 0.4737
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0226 0.3221
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0234
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0482 0.0482
Brugia malayi Serotonin receptor 0.0328 0.1477 0.1967
Echinococcus multilocularis microtubule associated protein 2 0.137 0.6397 0.6397
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0337 0.1518 0.3837
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0023 0.0023
Echinococcus multilocularis tubulin subunit beta 0.0023 0.0036 0.0036
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0098 0.095
Echinococcus granulosus intermediate filament protein 0.0031 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0129 0.0172
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0079 0.0304 0.0304
Brugia malayi ecdysteroid receptor 0.0042 0.0129 0.0172
Loa Loa (eye worm) tubulin beta-4 chain 0.0023 0.0036 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0363 0.0363
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0509
Brugia malayi hypothetical protein 0.002 0.0023 0.0031
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Entamoeba histolytica tubulin family protein 0.0023 0.0036 0.003
Loa Loa (eye worm) G-protein coupled receptor 0.0328 0.1477 0.1477
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0141 0.137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0129 0.0129
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0491 0.0491
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.084 0.3897 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0023 0.0023
Loa Loa (eye worm) TWK-28 protein 0.0023 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0129 0.0129
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0231 0.0231
Echinococcus multilocularis neuropeptides capa receptor 0.0328 0.1477 0.1477
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0079 0.0304 0.0304
Schistosoma mansoni amine GPCR 0.0328 0.1477 0.1477
Echinococcus multilocularis tubulin beta 1 chain 0.0023 0.0036 0.0036
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0328 0.1477 0.1477
Brugia malayi ORL1-like opioid receptor 0.0328 0.1477 0.1967
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0129 0.0129
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0226 0.0492
Echinococcus multilocularis sodium and chloride dependent glycine 0.0064 0.0231 0.0231
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0129 0.0129
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0056 0.0193 0.0402
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni lamin 0.0031 0.0074 0.0074
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0074 0.0099
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0593 0.144
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0063 0.0226 0.0149
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0328 0.1477 0.1477
Schistosoma mansoni microtubule-associated protein tau 0.137 0.6397 0.6397
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0231 0.0231
Schistosoma mansoni neuropeptide receptor 0.0328 0.1477 0.1477
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.0037 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Echinococcus multilocularis lamin 0.0031 0.0074 0.0074
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0328 0.1477 0.1967
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0226 0.0149
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0129 0.0129
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0007 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0129 0.0129
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0328 0.1477 0.1477
Onchocerca volvulus 0.002 0.0023 0.0073
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0129 0.0129
Leishmania major calcium/potassium channel (CAKC), putative 0.0023 0.0037 0.0364
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.084 0.3897 1
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0035 0.0046
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0056 0.0193 0.0402
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1029 0.4423
Mycobacterium tuberculosis Probable dehydrogenase 0.0337 0.1518 0.3837
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0035 0.0035
Toxoplasma gondii hypothetical protein 0.0024 0.004 0.0535
Schistosoma mansoni sodium/chloride dependent transporter 0.0065 0.0234 0.0234
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.017 0.2638
Trypanosoma cruzi ion transport protein, putative 0.0023 0.0037 0.0364
Schistosoma mansoni growth hormone secretagogue receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis 6 phosphofructokinase 0.0233 0.1029 0.1029
Leishmania major cytochrome p450-like protein 0.0056 0.0193 0.1873
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0056 0.0193 0.0402
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0233 0.1029 0.2568
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0069 0.0675
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0141 0.0864
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.362
Loa Loa (eye worm) calcium channel 0.0079 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Brugia malayi Inositol-1 0.0079 0.03 0.04
Toxoplasma gondii hypothetical protein 0.0064 0.0231 0.362
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0069 0.0566
Loa Loa (eye worm) cytochrome P450 family protein 0.0184 0.0799 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) thioredoxin reductase 0.0148 0.0626 0.0626
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0204 0.0204
Echinococcus granulosus cytochrome P450 2K1 0.0056 0.0193 0.0193
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0204 0.0204
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0193 0.1873
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.017 0.1656
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0005
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.084 0.3897 1
Trypanosoma brucei protein kinase, putative 0.0058 0.0204 0.1983
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0698 0.0698
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0069 0.0299
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0141 0.137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Toxoplasma gondii hypothetical protein 0.0064 0.0231 0.362
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0063 0.0226 0.0972
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) melatonin receptor type 1A 0.0328 0.1477 0.1477
Echinococcus granulosus 7tm_1 domain containing protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0056 0.0193 0.0402
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0029 0.0067 0.0651
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0099 0.0428
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.017 0.0732
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0079 0.03 0.0681
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.0036 0.0036
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.017 0.0348
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.1289 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Brugia malayi nuclear hormone receptor 0.002 0.0023 0.0031
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.0036 0.0036
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0099 0.0428
Schistosoma mansoni alpha-1 adrenergic receptor 0.0328 0.1477 0.1477
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0363 0.0363
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0509
Loa Loa (eye worm) hypothetical protein 0.2133 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0094 0.0125
Schistosoma mansoni alpha glucosidase 0.0036 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0129 0.0129
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.03 0.2918
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0094
Echinococcus granulosus tachykinin peptides receptor 99D 0.0328 0.1477 0.1477
Plasmodium falciparum glutathione reductase 0.0051 0.017 0.0348
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0374 0.1696 0.4296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1029 0.4423
Plasmodium vivax hypothetical protein, conserved 0.0064 0.0231 0.3306
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi Cytochrome P450 family protein 0.0056 0.0193 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0129 0.0172
Toxoplasma gondii cytochrome p450 superfamily protein 0.0056 0.0193 0.3
Echinococcus granulosus neuropeptide Y receptor 0.0328 0.1477 0.1477
Brugia malayi hypothetical protein 0.0023 0.0037 0.005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0156 0.0643
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0064 0.0231 0.0231
Schistosoma mansoni sodium/chloride dependent transporter 0.0064 0.0231 0.0231
Schistosoma mansoni alpha-glucosidase 0.014 0.0591 0.0591
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0088 0.0343 0.0791
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis g-protein coupled receptor 0.0328 0.1477 0.1477
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.0037 0.0364
Schistosoma mansoni voltage-gated cation channel 0.0079 0.0304 0.0304
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0006 0.0009
Echinococcus granulosus fmrfamide receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0074 0.0074
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0038 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Echinococcus granulosus dro:myosuppressin receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni coup transcription factor 0.0042 0.0129 0.0129
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0328 0.1477 0.1477
Schistosoma mansoni biogenic amine (5HT) receptor 0.0328 0.1477 0.1477
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0077 0.0292 0.0292
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0129 0.0172
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0509
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0064 0.0231 0.0308
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0023 0.0023
Loa Loa (eye worm) CYP4Cod1 0.0184 0.0799 0.0799
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0118 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0098 0.042
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Echinococcus multilocularis neuropeptide receptor 0.0328 0.1477 0.1477
Schistosoma mansoni neuropeptide receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.03 0.1291
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Schistosoma mansoni biogenic amine receptor 0.0328 0.1477 0.1477
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0056 0.0193 0.0402
Loa Loa (eye worm) solute carrier family 6 member 4 0.0377 0.1709 0.1709
Trypanosoma brucei cytochrome P450, putative 0.0184 0.0799 0.7763
Plasmodium vivax thioredoxin reductase, putative 0.0148 0.0626 1
Echinococcus granulosus lamin 0.0031 0.0074 0.0074
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0005
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Brugia malayi SET domain containing protein 0.0015 0.0002 0.0002
Schistosoma mansoni chromobox protein 0.008 0.0305 0.0305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0098 0.042
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0023 0.0073
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0032 0.0032
Plasmodium falciparum potassium channel 0.0023 0.0037 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0129 0.0171
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Trichomonas vaginalis inositol monophosphatase, putative 0.0079 0.03 0.1291
Entamoeba histolytica tubulin family protein 0.0023 0.0036 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0056 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0099 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0035 0.0035
Echinococcus granulosus serotonin receptor 0.0328 0.1477 0.1477
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0005 0.0007
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0069 0.0266
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0063 0.0226 0.1541
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0056 0.0193 0.0402
Schistosoma mansoni nuclear receptor 0.002 0.0023 0.0023
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.017 0.0227
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Echinococcus multilocularis flap endonuclease 1 0.003 0.0069 0.0069
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0023 0.0037 0.005
Echinococcus multilocularis lamin dm0 0.0031 0.0074 0.0074
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0118 0.0118
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0129 0.0172
Brugia malayi conserved hypotetical protein 0.002 0.0023 0.0031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.017 0.0344
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0036 0.0155
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0023 0.0037 0.005
Schistosoma mansoni hypothetical protein 0.0144 0.0609 0.0609
Brugia malayi Melibiase family protein 0.0078 0.0298 0.0397
Echinococcus multilocularis twik family of potassium channels 0.0023 0.0037 0.0037
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0328 0.1477 0.1477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0057 0.02 0.086
Brugia malayi nuclear receptor NHR-88 0.002 0.0023 0.0031
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0098 0.095
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0363 0.0363
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0023 0.0037 0.005
Echinococcus multilocularis neuropeptide FF receptor 2 0.0328 0.1477 0.1477
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0129 0.0129
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0204 0.1983
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0148 0.0626 0.1524
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.1289 0.3002
Brugia malayi RE15519p 0.0328 0.1477 0.1967
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0698 0.0698
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0006 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0328 0.1477 0.1477
Schistosoma mansoni intermediate filament proteins 0.0031 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0129 0.0172
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0023 0.0023
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Onchocerca volvulus 0.0377 0.1709 0.7339
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0141 0.137
Brugia malayi sulfakinin receptor protein 0.0328 0.1477 0.1967
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0328 0.1477 0.1477
Echinococcus granulosus biogenic amine 5HT receptor 0.0328 0.1477 0.1477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0023 0.0037 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0134 0.0134
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0023 0.0037 0.005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0328 0.1477 0.1477
Schistosoma mansoni hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0141 0.0141
Schistosoma mansoni adenoreceptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Trichomonas vaginalis chromobox protein, putative 0.008 0.0305 0.1311
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1155 0.5385 0.5385
Schistosoma mansoni sodium/chloride dependent transporter 0.0377 0.1709 0.1709
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0231 0.3618
Entamoeba histolytica hypothetical protein 0.0035 0.0096 0.0509
Toxoplasma gondii beta tubulin 0.0023 0.0036 0.0468
Schistosoma mansoni neuropeptide f receptor 76f 0.0328 0.1477 0.1477
Schistosoma mansoni biogenic amine (5HT) receptor 0.2133 1 1
Trypanosoma brucei beta tubulin 0.0023 0.0036 0.0351
Leishmania major hypothetical protein, conserved 0.0025 0.0048 0.0465
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni thyroid hormone receptor 0.0186 0.0809 0.0809
Brugia malayi cytochrome P450 0.0056 0.0193 0.0257
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.017 0.1656
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.014 0.0601
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0069 0.0675
Loa Loa (eye worm) voltage-dependent calcium channel 0.0029 0.0067 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0363 0.0363
Echinococcus multilocularis dro:myosuppressin receptor 0.0328 0.1477 0.1477
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0007 0.0007
Echinococcus granulosus GPCR family 2 0.0016 0.0005 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0328 0.1477 0.1477
Echinococcus granulosus neuropeptides capa receptor 0.0328 0.1477 0.1477
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0129 0.0129
Brugia malayi nuclear receptor RXR 0.0022 0.0035 0.0046
Echinococcus granulosus g protein coupled receptor 0.0328 0.1477 0.1477
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.014 0.0601
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0193 0.0193
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.0231
Echinococcus multilocularis calcium activated potassium channel variant 0.0023 0.0037 0.0037
Schistosoma mansoni nuclear hormone receptor 0.002 0.0023 0.0023
Brugia malayi Pre-SET motif family protein 0.0446 0.2035 0.2711
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0099 0.0133
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Leishmania major hypothetical protein, conserved 0.0023 0.0037 0.0364
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus granulosus somatostatin receptor 0.0328 0.1477 0.1477
Trypanosoma brucei calcium-activated potassium channel, putative 0.0023 0.0037 0.0364
Loa Loa (eye worm) hypothetical protein 0.0078 0.0298 0.0298
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.022 0.022
Trypanosoma brucei beta tubulin 0.0023 0.0036 0.0351
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0029 0.0067 0.0067
Onchocerca volvulus 0.0328 0.1477 0.6337
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0017 0.0165
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0593 0.144
Echinococcus granulosus neuropeptide receptor A26 0.0328 0.1477 0.1477
Schistosoma mansoni alpha-glucosidase 0.014 0.0591 0.0591
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0078 0.0336
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Echinococcus multilocularis fmrfamide receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0204 0.1983
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0032 0.0032
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0328 0.1477 0.1477
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0328 0.1477 0.1477
Leishmania major hypothetical protein, conserved 0.0023 0.0037 0.0364
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0064 0.0231 0.0231
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0023 0.0073
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0032 0.0043
Onchocerca volvulus 0.0328 0.1477 0.6337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0067 0.0286
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0023 0.0023
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0099 0.0428
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0129 0.0129
Treponema pallidum sodium- and chloride- dependent transporter 0.0377 0.1709 0.4129
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0064 0.0231 0.0231
Mycobacterium ulcerans 6-phosphofructokinase 0.0233 0.1029 0.2568
Onchocerca volvulus 0.002 0.0023 0.0073
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0029 0.0067 0.0651
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.017 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0098 0.042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0328 0.1477 0.1477
Brugia malayi Cytochrome P450 family protein 0.0184 0.0799 0.1064
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0032 0.0139
Loa Loa (eye worm) hypothetical protein 0.1604 0.7505 0.7505
Mycobacterium ulcerans endonuclease IV 0.0088 0.0343 0.0791
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0023 0.0037 0.005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0056 0.0193 0.0402
Echinococcus granulosus tm gpcr rhodopsin 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0035 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0129 0.0172
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0032 0.0032
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Echinococcus granulosus sodium and chloride dependent glycine 0.0064 0.0231 0.0231
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0056 0.0193 0.0402
Brugia malayi neuropeptide F receptor 0.0328 0.1477 0.1967
Trypanosoma cruzi trypanothione reductase, putative 0.0148 0.0626 0.6082
Onchocerca volvulus 0.0328 0.1477 0.6337
Schistosoma mansoni chromobox protein 0.008 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0204 0.0204
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.017 0.1656
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0446 0.2035 0.2035
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0204 0.0204
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0079 0.03 0.2131
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0056 0.0193 0.0402
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0048 0.0465
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0088 0.0343 0.0343
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0006 0.0006
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0037 0.0037
Plasmodium falciparum transporter, putative 0.0064 0.0231 0.0505
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0023 0.0037 0.0037
Onchocerca volvulus 0.0508 0.2326 1
Brugia malayi nuclear hormone receptor 0.0042 0.0129 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0129 0.0129
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0032 0.0032
Brugia malayi beta-tubulin, identical 0.0023 0.0036 0.0048
Echinococcus granulosus peptide allatostatin:somatostatin 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0035 0.0096 0.0096
Leishmania major ion transport protein-like protein 0.0023 0.0037 0.0364
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0328 0.1477 0.1477
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0056 0.0193 0.0402
Plasmodium vivax amine transporter, putative 0.0064 0.0231 0.3306
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0261 0.058
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0056 0.0193 0.0402
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0129 0.0129
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0337 0.1518 0.3837
Schistosoma mansoni hypothetical protein 0.0035 0.0094 0.0094
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.017 0.1656
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0129 0.053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0023 0.0023
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0079 0.0304 0.0304
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.017 0.0348
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0099 0.0099
Chlamydia trachomatis endonuclease IV 0.0088 0.0343 0.0462
Brugia malayi putative neuropeptide receptor NPR1 0.0328 0.1477 0.1967
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Onchocerca volvulus 0.0031 0.0074 0.0293
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0129 0.0129
Brugia malayi follicle stimulating hormone receptor 0.0328 0.1477 0.1967
Echinococcus multilocularis expressed protein 0.0427 0.1944 0.1944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.011 0.0473
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0037 0.0364
Echinococcus granulosus death domain containing protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) inositol-1 0.0079 0.03 0.03
Echinococcus multilocularis conserved hypothetical protein 0.069 0.3186 0.3186
Echinococcus granulosus hypothetical protein 0.1017 0.4734 0.4734
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni amine GPCR 0.0328 0.1477 0.1477
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0035 0.0046
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0233 0.1029 0.2568
Onchocerca volvulus 0.0023 0.0037 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Schistosoma mansoni histamine h1 receptor 0.0328 0.1477 0.1477
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Brugia malayi 6-phosphofructokinase 0.0233 0.1029 0.1371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.0016 0.0006 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0298 0.0298
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0226 0.3221
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0042 0.0129 0.053
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0064 0.0231 0.0308
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0328 0.1477 0.1477
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0877
Loa Loa (eye worm) hypothetical protein 0.0377 0.1709 0.1709
Echinococcus multilocularis G protein coupled receptor 139 0.0328 0.1477 0.1477
Echinococcus granulosus inositol monophosphatase 1 0.0079 0.03 0.03
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0129 0.0129
Echinococcus multilocularis twik family of potassium channels 0.0023 0.0037 0.0037
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0023 0.0037 0.005
Brugia malayi hypothetical protein 0.0023 0.0037 0.005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0129 0.0129
Brugia malayi ecdysone receptor 0.002 0.0023 0.0031
Echinococcus granulosus calcium activated potassium channel variant 0.0023 0.0037 0.0037
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0007 0.0007
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0118 0.0158
Schistosoma mansoni biogenic amine receptor 0.0328 0.1477 0.1477
Echinococcus granulosus tm gpcr rhodopsin 0.1155 0.5385 0.5385
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0553
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0482 0.0482
Loa Loa (eye worm) tubulin beta chain 0.0023 0.0036 0.0036
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0023 0.0037 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0088 0.0343 0.0457
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1289 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0363 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0078 0.0336
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0141 0.137
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0129 0.0172
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0343 0.52
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0593 0.144
Brugia malayi intermediate filament protein 0.0031 0.0074 0.0099
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0084 0.0326 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0187
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0328 0.1477 0.1477
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0129 0.0129
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0204 0.1983
Trypanosoma brucei beta tubulin 0.0023 0.0036 0.0351
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.0106 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Echinococcus multilocularis beta tubulin 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0482 0.0482
Brugia malayi Cytochrome P450 family protein 0.0056 0.0193 0.0257
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.017 0.017
Brugia malayi steroid hormone receptor 0.0042 0.0129 0.0172
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0023 0.0037 0.005
Onchocerca volvulus 0.0064 0.0231 0.0968
Echinococcus multilocularis rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0088 0.0343 0.079
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0328 0.1477 0.1477
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.0037 0.0364
Schistosoma mansoni thyroid hormone receptor 0.0186 0.0809 0.0809
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0482 0.7674
Schistosoma mansoni myosin xvIII 0.0328 0.1477 0.1477
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0305 0.0305
Echinococcus granulosus chromobox protein 1 0.008 0.0305 0.0305
Brugia malayi G protein-coupled receptor F59B2.13 0.0328 0.1477 0.1967
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis serotonin transporter 0.0377 0.1709 0.1709
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1029 0.7928
Echinococcus granulosus sodium and chloride dependent glycine 0.0064 0.0231 0.0231
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0096 0.0096
Echinococcus granulosus tubulin subunit beta 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0063 0.0226 0.3538
Trichomonas vaginalis tubulin, putative 0.0023 0.0036 0.0155
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) neuropeptide F receptor 0.0328 0.1477 0.1477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0023 0.0037 0.005
Plasmodium vivax glutathione reductase, putative 0.0148 0.0626 1
Onchocerca volvulus 0.0023 0.0037 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis GPCR, family 2 0.0016 0.0005 0.0005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0031 0.0074 0.0074
Echinococcus granulosus expressed protein 0.0427 0.1944 0.1944
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0023 0.0037 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Schistosoma mansoni hypothetical protein 0.0023 0.0037 0.0037
Onchocerca volvulus 0.0077 0.0292 0.1233
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0023 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Toxoplasma gondii phosphofructokinase PFKII 0.0063 0.0226 0.3538
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Plasmodium falciparum thioredoxin reductase 0.0051 0.017 0.0348
Loa Loa (eye worm) cytochrome P450 0.0056 0.0193 0.0193
Mycobacterium tuberculosis Probable reductase 0.0337 0.1518 0.3837
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0023 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Schistosoma mansoni amine GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus multilocularis potassium channel subfamily K 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis neuropeptide receptor A26 0.0328 0.1477 0.1477
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0129 0.0172
Trypanosoma cruzi beta tubulin, putative 0.0023 0.0036 0.0351
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0037 0.0037
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0023 0.0037 0.0041
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0006 0.0006
Onchocerca volvulus 0.0023 0.0037 0.0134
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.0037 0.0364
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0037 0.0037
Echinococcus multilocularis thyroid hormone receptor alpha 0.0186 0.0809 0.0809
Schistosoma mansoni sodium-dependent amino acid transporter 0.0064 0.0231 0.0231
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0129 0.0172
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0363 0.0363
Onchocerca volvulus 0.0328 0.1477 0.6337
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus granulosus beta tubulin 0.0023 0.0036 0.0036
Giardia lamblia Hypothetical protein 0.0023 0.0037 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0037 0.0364
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0048 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0139
Brugia malayi G protein-coupled receptor 0.0328 0.1477 0.1967
Brugia malayi larval opioid receptor 0.0328 0.1477 0.1967
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0193 0.1873
Entamoeba histolytica Flap nuclease, putative 0.003 0.0069 0.0295
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0099 0.0099
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0032 0.0032
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0363 0.0484
Echinococcus granulosus lamin dm0 0.0031 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0087 0.0372
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.017 0.0344
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus granulosus G protein coupled receptor 139 0.0328 0.1477 0.1477
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0096 0.0096
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0099 0.0534
Echinococcus granulosus flap endonuclease 1 0.003 0.0069 0.0069
Echinococcus granulosus chromobox protein 1 0.008 0.0305 0.0305
Echinococcus granulosus neuropeptide s receptor 0.0328 0.1477 0.1477
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0064 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0023 0.0037 0.0364
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0056 0.0193 0.0402
Echinococcus granulosus small conductance calcium activated potassium 0.0023 0.0037 0.0037
Trichomonas vaginalis chromobox protein, putative 0.008 0.0305 0.1311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0056 0.0239
Leishmania major ATP-dependent phosphofructokinase 0.0233 0.1029 1
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Brugia malayi Dopamine receptor 0.0328 0.1477 0.1967
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.017 0.1656
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0023 0.0037 0.0037
Brugia malayi GnHR receptor homolog 0.0328 0.1477 0.1967
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0129 0.0553
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0064 0.0231 0.0968
Loa Loa (eye worm) DR-78 0.002 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0056 0.0193 0.0402
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0035 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0129 0.0553
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.017 0.1656
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1029 0.7928
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Brugia malayi hypothetical protein 0.0022 0.0035 0.0046
Echinococcus multilocularis fmrfamide receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1289 1
Brugia malayi hypothetical protein 0.0328 0.1477 0.1967
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0231
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.006 0.026
Schistosoma mansoni netrin receptor unc5 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0186
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0069 0.0675
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0023 0.0023
Brugia malayi G-protein coupled receptor 0.0328 0.1477 0.1967
Schistosoma mansoni opsin-like receptor 0.0328 0.1477 0.1477
Echinococcus granulosus tm gpcr rhodopsin 0.0328 0.1477 0.1477
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0374 0.1696 0.4297
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Brugia malayi Dopamine receptor protein 1 0.0328 0.1477 0.1967
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Onchocerca volvulus 0.0328 0.1477 0.6337
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0023 0.0037 0.005
Echinococcus granulosus serotonin transporter 0.0377 0.1709 0.1709
Echinococcus granulosus nuclear factor of activated T cells 5 0.0084 0.0326 0.0326
Brugia malayi Nuclear hormone receptor E75 0.002 0.0023 0.0031
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0079 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.1604 0.7505 0.7505
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0064 0.0231 0.0231
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0129 0.0129
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0056 0.0193 0.0402
Brugia malayi Tubulin beta-1 chain 0.0023 0.0036 0.0048
Loa Loa (eye worm) uncoordinated protein 58 0.0023 0.0037 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0056 0.0193 0.0402
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0328 0.1477 0.1477
Echinococcus multilocularis sodium and chloride dependent glycine 0.0064 0.0231 0.0231
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.084 0.3897 1
Echinococcus multilocularis neuropeptides capa receptor 0.0328 0.1477 0.1477
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0006 0.0006
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0328 0.1477 0.1967
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0877
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0226 0.0972
Schistosoma mansoni opsin-like receptor 0.0328 0.1477 0.1477
Loa Loa (eye worm) BEN-1 protein 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0328 0.1477 0.6337
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.0036 0.0036
Schistosoma mansoni nuclear receptor 0.002 0.0023 0.0023
Brugia malayi hypothetical protein 0.002 0.0023 0.0031
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0129 0.0129
Brugia malayi Tachykinin-like peptides receptor 99D 0.0328 0.1477 0.1967
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0328 0.1477 0.1477
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0204 0.134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.017 0.1656
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0032 0.0032
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.017 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1289 0.5543
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0328 0.1477 0.1477
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.03 0.2918
Leishmania major beta tubulin 0.0023 0.0036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0328 0.1477 0.1477
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0037 0.0037
Schistosoma mansoni tubulin subunit beta 0.0023 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0328 0.1477 0.1477
Loa Loa (eye worm) hypothetical protein 0.0079 0.0304 0.0304
Echinococcus multilocularis inositol monophosphatase 1 0.0079 0.03 0.03
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.0036 0.0036
Trypanosoma brucei beta tubulin 0.0023 0.0036 0.0351
Brugia malayi Cytochrome P450 family protein 0.0184 0.0799 0.1064
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0204 0.0877
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0056 0.0193 0.0402

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 6.3 nM Displacement of [125](E)-3-(4-(Dimethylamino-phenyl)-1-(4-iodophenyl)prop-2-en-1-one from beta amyloid(1-42) aggregates ChEMBL. 17826102

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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