Detailed information for compound 46399

Basic information

Technical information
  • TDR Targets ID: 46399
  • Name: N-cyclohexylhexadecanamide
  • MW: 337.583 | Formula: C22H43NO
  • H donors: 1 H acceptors: 1 LogP: 8.68 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC(=O)NC1CCCCC1
  • InChi: 1S/C22H43NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-22(24)23-21-18-15-14-16-19-21/h21H,2-20H2,1H3,(H,23,24)
  • InChiKey: OXNIVLAQPVUFDE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-cyclohexylpalmitamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans hypothetical protein 0.019 0.1125 0.3578
Schistosoma mansoni glutamate receptor NMDA 0.0131 0.0692 0.0664
Onchocerca volvulus 0.0047 0.0086 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.1199 0.3664
Onchocerca volvulus 0.0447 0.2987 0.3422
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0235 0.0231
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus oxidoreductase 0.0047 0.0086 0.0063
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0211 0.1275 0.1403
Schistosoma mansoni tyrosine kinase 0.0069 0.0245 0.0216
Loa Loa (eye worm) hypothetical protein 0.0054 0.014 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.1199 0.3664
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0047 0.0086 0.0152
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0335 0.2172 1
Trichomonas vaginalis adenylate cyclase, putative 0.0041 0.0043 0.0018
Leishmania major importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0119 0.0258
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0447 0.2987 0.3458
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.038 0.2502 0.811
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.024 0.0372
Mycobacterium tuberculosis Possible oxidoreductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Brugia malayi beta-lactamase family protein 0.019 0.1125 0.1748
Schistosoma mansoni retinoic acid receptor RXR 0.0447 0.2987 0.2966
Brugia malayi Thioredoxin reductase 0.0052 0.0119 0.0186
Echinococcus multilocularis epidermal growth factor receptor 0.0191 0.1129 0.1239
Schistosoma mansoni aldehyde dehydrogenase 0.046 0.3076 0.3055
Echinococcus granulosus receptor type guanylyl cyclase 0.0069 0.0245 0.0243
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0211 0.1275 0.1248
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Brugia malayi Metabotropic glutamate receptor precursor. 0.0067 0.0231 0.0358
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Toxoplasma gondii oxidoreductase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) nuclear receptor NHR-67 0.0211 0.1275 0.145
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0085 0.0358 0.2315
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0447 0.2987 0.3334
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0447 0.2987 0.3334
Echinococcus granulosus apoptotic protease activating factor 1 0.0445 0.297 0.3315
Onchocerca volvulus Bile acid receptor homolog 0.0447 0.2987 0.3422
Trichomonas vaginalis esterase, putative 0.019 0.1125 0.3429
Brugia malayi Protein kinase domain containing protein 0.0062 0.0192 0.0299
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0047 0.0086 0.0152
Entamoeba histolytica hypothetical protein 0.0047 0.0086 0.1802
Echinococcus multilocularis receptor type guanylyl cyclase 0.0069 0.0245 0.0243
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0447 0.2987 0.3334
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Brugia malayi hypothetical protein 0.0047 0.0086 0.0133
Echinococcus multilocularis aryl hydrocarbon receptor 0.0041 0.0043 0.0015
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0062 0.0197 0.0187
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Brugia malayi hypothetical protein 0.0236 0.1458 0.2267
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.046 0.3076 0.3589
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) tubulin beta-2A chain 0.0049 0.0102 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0211 0.1275 0.1248
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0062 0.0192 0.0183
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0118 0.0599 0.3899
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0047 0.0086 0.0092
Onchocerca volvulus 0.0047 0.0086 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Schistosoma mansoni coup transcription factor 0.0447 0.2987 0.2966
Leishmania major hypothetical protein, conserved 0.0084 0.0353 0.0994
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.046 0.3076 0.9584
Loa Loa (eye worm) tubulin beta-1 chain 0.0049 0.0102 0.0076
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0131 0.0692 0.0746
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0119 0.0101
Brugia malayi hydrolase, alpha/beta fold family protein 0.0615 0.4204 0.6536
Echinococcus multilocularis peptidase Clp (S14 family) 0.0161 0.0912 0.0994
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Schistosoma mansoni tyrosine kinase 0.0191 0.1129 0.1102
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0236 0.1458 0.161
Schistosoma mansoni thyroid hormone receptor 0.0447 0.2987 0.2966
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0403 0.2669 0.3113
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0047 0.0086 0.0063
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.029 0.1848 0.2122
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0047 0.0086 0.0152
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis beta LACTamase domain containing family member 0.019 0.1125 0.1234
Brugia malayi Glycosyl hydrolases family 31 protein 0.037 0.2426 0.3771
Trypanosoma cruzi extracellular receptor, putative 0.0067 0.0231 0.0609
Trypanosoma brucei trypanothione reductase 0.0052 0.0119 0.0258
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Brugia malayi N-terminal motif family protein 0.0193 0.1141 0.1773
Leishmania major pteridine reductase 1 0.0047 0.0086 0.0152
Brugia malayi nuclear hormone receptor family member nhr-6 0.0211 0.1275 0.1981
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0358 0.0898
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Echinococcus multilocularis epidermal growth factor receptor 0.0103 0.0492 0.0521
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Toxoplasma gondii thioredoxin reductase 0.0052 0.0119 0.0258
Echinococcus granulosus glutamate NMDA receptor subunit 0.0131 0.0692 0.0746
Loa Loa (eye worm) glutamate receptor 2 0.0131 0.0692 0.0767
Brugia malayi Cell death protein 3 precursor 0.0923 0.6433 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Echinococcus granulosus JmjC domain containing protein 4 0.0084 0.0353 0.0364
Brugia malayi Glutamate receptor 2 precursor 0.0131 0.0692 0.1076
Leishmania major short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0119 0.0101
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Chlamydia trachomatis glutamine binding protein 0.0335 0.2172 1
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0047 0.0086 0.0063
Brugia malayi nuclear hormone receptor 0.0447 0.2987 0.4644
Loa Loa (eye worm) STAT protein 0.0153 0.0851 0.0954
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0246 0.1525 0.4693
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.037 0.2426 0.2799
Plasmodium falciparum tubulin beta chain 0.0049 0.0102 0.0079
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.019 0.1125 0.3578
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Echinococcus multilocularis beta tubulin 0.0049 0.0102 0.0082
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Brugia malayi ecdysone receptor 0.0211 0.1275 0.1981
Echinococcus granulosus caspase 3 0.0785 0.5438 0.6096
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.034 0.0529
Schistosoma mansoni glutamate receptor NMDA 0.0198 0.1177 0.1151
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.046 0.3076 0.3434
Trichomonas vaginalis steroid dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni tyrosine kinase 0.0062 0.0192 0.0163
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0478 0.3208 0.3187
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0069 0.0243 0.0647
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0447 0.2987 0.3458
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0211 0.1275 0.1403
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0468 0.0728
Echinococcus multilocularis steroid dehydrogenase 0.0047 0.0086 0.0063
Plasmodium falciparum importin beta, putative 0.0062 0.0197 0.0381
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Brugia malayi Importin beta-1 subunit 0.0062 0.0197 0.0306
Echinococcus multilocularis lysosomal alpha glucosidase 0.037 0.2426 0.2701
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Onchocerca volvulus 0.0047 0.0086 0.0049
Brugia malayi hypothetical protein 0.0039 0.003 0.0047
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Onchocerca volvulus 0.0047 0.0086 0.0049
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Schistosoma mansoni hypothetical protein 0.0445 0.297 0.2949
Echinococcus multilocularis caspase 3 0.0785 0.5438 0.6096
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0211 0.1275 0.1431
Mycobacterium ulcerans oxidoreductase 0.0047 0.0086 0.0159
Echinococcus granulosus jumonji domain containing 1A 0.0084 0.0353 0.0364
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Leishmania major GTP-binding protein, putative 0.0046 0.0078 0.0126
Plasmodium vivax glutathione reductase, putative 0.0052 0.0119 0.0134
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0131 0.0694 0.4527
Echinococcus granulosus Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0335 0.2172 1
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0447 0.2987 0.4644
Echinococcus granulosus hypothetical protein 0.0047 0.0086 0.0063
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0047 0.0086 0.0152
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0047 0.0086 0.0049
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Echinococcus granulosus metabotropic glutamate receptor 2 0.0067 0.0231 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis glutamate receptor 2 0.0067 0.0231 0.0226
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.1125 0.3429
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0257 0.161 0.1584
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Entamoeba histolytica short chain dehydrogenase family protein 0.0047 0.0086 0.1802
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0403 0.2669 0.8661
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Leishmania major short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0235 0.0231
Mycobacterium ulcerans epoxide hydrolase EphA 0.0395 0.2606 0.8455
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable dehydrogenase 0.0047 0.0086 0.0092
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Plasmodium falciparum steroid dehydrogenase, putative 0.0047 0.0086 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.019 0.1125 0.1274
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Echinococcus granulosus tubulin subunit beta 0.0049 0.0102 0.0082
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Brugia malayi RNA binding protein 0.0068 0.0235 0.0365
Schistosoma mansoni alpha-glucosidase 0.0318 0.2053 0.2029
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni phd/f-box containing protein 0.0084 0.0353 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0403 0.2669 0.2647
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Brugia malayi Melibiase family protein 0.0157 0.0884 0.1375
Trichomonas vaginalis tubulin, putative 0.0049 0.0102 0.0204
Echinococcus granulosus insulin receptor 0.0062 0.0192 0.0183
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Schistosoma mansoni alpha glucosidase 0.0082 0.034 0.0311
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0119 0.0132
Echinococcus granulosus glutamate receptor subunit protein glur 0.0131 0.0692 0.0746
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.014 0.0323
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Onchocerca volvulus 0.0047 0.0086 0.0049
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Plasmodium vivax metacaspase 1, putative 0.0478 0.3208 1
Brugia malayi hypothetical protein 0.0054 0.014 0.0217
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0131 0.0694 0.0804
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0447 0.2987 0.3334
Schistosoma mansoni nuclear hormone receptor 0.0211 0.1275 0.1248
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0131 0.0694 0.0804
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0047 0.0086 0.3356
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0041 0.0043 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.1125 0.3429
Loa Loa (eye worm) tubulin beta chain 0.0049 0.0102 0.0076
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0118 0.0599 0.0692
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Loa Loa (eye worm) hypothetical protein 0.0246 0.1525 0.1744
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) glutamate receptor 0.0067 0.0231 0.0226
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0047 0.0086 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0236 0.1458 0.2267
Echinococcus multilocularis 0.0059 0.0171 0.0159
Schistosoma mansoni steroid hormone receptor ad4bp 0.0447 0.2987 0.2966
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0084 0.0353 0.0324
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0047 0.0086 0.0152
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.034 0.035
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0403 0.2669 0.2975
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Loa Loa (eye worm) nuclear hormone receptor 0.0211 0.1275 0.145
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0047 0.0086 0.0063
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0067 0.0231 0.0226
Echinococcus granulosus tyrosine protein kinase shark 0.0217 0.1319 0.1454
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0246 0.1525 0.1686
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Echinococcus multilocularis muscleblind protein 0.067 0.4602 0.5154
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.034 0.0954
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni ran 0.0046 0.0078 0.0048
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Loa Loa (eye worm) hypothetical protein 0.067 0.4602 0.535
Schistosoma mansoni single-minded 0.0158 0.0892 0.0865
Echinococcus multilocularis steroid dehydrogenase 0.0047 0.0086 0.0063
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Trichomonas vaginalis ran, putative 0.0046 0.0078 0.0126
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0211 0.1275 0.1981
Echinococcus granulosus thyroid hormone receptor alpha 0.0211 0.1275 0.1403
Echinococcus multilocularis NMDA receptor 0.0131 0.0692 0.0746
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Brugia malayi MH2 domain containing protein 0.0398 0.2629 0.4087
Schistosoma mansoni caspase-3 (C14 family) 0.1263 0.89 0.8897
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0173 0.0428
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0447 0.2987 0.3458
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0478 0.3208 0.4987
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.1125 0.3429
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0058 0.0164 0.0184
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0038 0.0009
Echinococcus multilocularis snurportin 1 0.0665 0.4566 0.5113
Mycobacterium tuberculosis Possible oxidoreductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0197 0.0502
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Toxoplasma gondii melibiase subfamily protein 0.0236 0.1454 0.4467
Trichomonas vaginalis tubulin alpha chain, putative 0.0049 0.0102 0.0204
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0102 0.0076
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Trypanosoma cruzi metacaspase 5, putative 0.0478 0.3208 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0118 0.0599 0.0692
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6961
Echinococcus granulosus nmda type glutamate receptor 0.0466 0.3119 0.3483
Schistosoma mansoni hypothetical protein 0.054 0.3657 0.3638
Onchocerca volvulus 0.0067 0.0231 0.0218
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0047 0.0086 0.0325
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0078 0.0126
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0084 0.0353 0.0994
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0447 0.2987 0.4644
Plasmodium vivax tubulin beta chain, putative 0.0049 0.0102 0.0079
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) hydrolase 0.1218 0.8569 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.049 0.3295 0.3819
Echinococcus multilocularis FTZ F1 alpha 0.0447 0.2987 0.3334
Brugia malayi Muscleblind-like protein 0.067 0.4602 0.7154
Brugia malayi Nuclear hormone receptor E75 0.0211 0.1275 0.1981
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0067 0.0231 0.0226
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0047 0.0086 0.0056
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis tyrosine kinase 0.0069 0.0245 0.0243
Onchocerca volvulus Sepiapterin reductase homolog 0.0047 0.0086 0.0049
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni retinal dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi steroid hormone receptor 0.0447 0.2987 0.4644
Mycobacterium tuberculosis Probable lipase LipD 0.019 0.1125 0.1307
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0161 0.0912 0.5961
Mycobacterium leprae Probable lipase LipE 0.019 0.1125 0.7361
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0447 0.2987 0.3334
Onchocerca volvulus 0.0214 0.1296 0.1455
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Onchocerca volvulus 0.0047 0.0086 0.0049
Brugia malayi Tubulin beta-1 chain 0.0049 0.0102 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.034 0.0954
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Toxoplasma gondii aldehyde dehydrogenase 0.046 0.3076 0.9584
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0161 0.0912 0.1058
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Schistosoma mansoni hypothetical protein 0.0665 0.4566 0.4549
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0468 0.0728
Mycobacterium ulcerans lipase LipD 0.019 0.1125 0.3578
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0131 0.0692 0.0746
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Onchocerca volvulus 0.0211 0.1275 0.1431
Onchocerca volvulus 0.0047 0.0086 0.0049
Onchocerca volvulus 0.019 0.1125 0.1257
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Onchocerca volvulus 0.0047 0.0086 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0314 0.2023 0.2327
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0047 0.0086 0.052
Brugia malayi Dehydrogenases, short chain protein 30 0.0047 0.0086 0.0133
Leishmania major hypothetical protein, conserved 0.0054 0.014 0.0323
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0197 0.0502
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.034 0.0954
Brugia malayi TAR-binding protein 0.0068 0.0235 0.0365
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0157 0.0884 0.0857
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0314 0.2023 0.2247
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0157 0.0884 0.0857
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Schistosoma mansoni ran 0.0046 0.0078 0.0048
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Schistosoma mansoni caspase-7 (C14 family) 0.0923 0.6433 0.6422
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) RNA binding protein 0.0068 0.0235 0.0231
Brugia malayi photoreceptor-specific nuclear receptor 0.0447 0.2987 0.4644
Schistosoma mansoni inositol monophosphatase 0.004 0.0038 0.0008
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Mycobacterium ulcerans putative regulatory protein 0.0117 0.0594 0.1832
Trypanosoma cruzi metacaspase 5, putative 0.0478 0.3208 1
Plasmodium falciparum metacaspase-like protein 0.0478 0.3208 1
Echinococcus multilocularis tubulin subunit beta 0.0049 0.0102 0.0082
Mycobacterium ulcerans carveol-like dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium leprae Probable oxidoreductase 0.0047 0.0086 0.052
Plasmodium falciparum thioredoxin reductase 0.0052 0.0119 0.0134
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Echinococcus multilocularis glutamate receptor 2 0.0198 0.1177 0.1294
Trypanosoma brucei metacaspase 5, putative 0.0478 0.3208 1
Brugia malayi nuclear receptor RXR 0.0211 0.1275 0.1981
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Plasmodium vivax steroid dehydrogenase, putative 0.0047 0.0086 0.0027
Trypanosoma cruzi short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0246 0.1525 0.4693
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0335 0.2172 1
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.0153 0.0851 0.1324
Onchocerca volvulus Cell death protein 3 homolog 0.0923 0.6433 0.7426
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni nuclear receptor nhr-48 0.0211 0.1275 0.1248
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0118 0.0599 0.0692
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0131 0.0692 0.0746
Entamoeba histolytica hypothetical protein, conserved 0.0047 0.0086 0.1802
Echinococcus granulosus tubulin beta 4A class IVa 0.0049 0.0102 0.0082
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0447 0.2987 0.3334
Brugia malayi Receptor family ligand binding region containing protein 0.0069 0.0245 0.0381
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Schistosoma mansoni ATP-binding cassette transporter 0.0131 0.0692 0.0664
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0118 0.0599 0.0692
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0041 0.0043 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Echinococcus granulosus geminin 0.054 0.3657 0.4089
Echinococcus granulosus tyrosine kinase 0.0069 0.0245 0.0243
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Brugia malayi Retinol dehydrogenase 12 0.0047 0.0086 0.0133
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0047 0.0086 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.029 0.0796
Mycobacterium tuberculosis Probable hydrolase 0.019 0.1125 0.1307
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0211 0.1275 0.1403
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0047 0.0086 0.0063
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0236 0.1454 0.1605
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0447 0.2987 0.2966
Onchocerca volvulus 0.0211 0.1275 0.1431
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0067 0.0231 0.0226
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis tubulin beta 1 chain 0.0049 0.0102 0.0082
Schistosoma mansoni carbonyl reductase 0.0047 0.0086 0.0056
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni RAR-like nuclear receptor 0.0447 0.2987 0.2966
Schistosoma mansoni zinc finger protein 0.0211 0.1275 0.1248
Loa Loa (eye worm) tubulin beta-4 chain 0.0049 0.0102 0.0076
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Echinococcus granulosus tar DNA binding protein 0.0068 0.0235 0.0231
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0665 0.4566 0.5308
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0236 0.1454 0.1605
Brugia malayi Glutamate receptor 1 precursor 0.0131 0.0692 0.1076
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.034 0.0954
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0038 0.0245
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Giardia lamblia Short-chain dehydrogenase, putative 0.0047 0.0086 0.3356
Toxoplasma gondii ABC1 family protein 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0447 0.2987 0.4644
Giardia lamblia Hypothetical protein 0.0047 0.0086 0.3356
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1216 0.8558 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0403 0.2669 0.83
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0062 0.0192 0.0183
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0069 0.0245 0.0244
Schistosoma mansoni jumonji domain containing protein 0.0314 0.2023 0.1999
Brugia malayi beta-lactamase family protein 0.019 0.1125 0.1748
Echinococcus multilocularis lysine specific demethylase 6a 0.0084 0.0353 0.0364
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.034 0.0355
Echinococcus multilocularis muscleblind protein 1 0.067 0.4602 0.5154
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Leishmania major oxidoreductase-like protein 0.0047 0.0086 0.0152
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.014 0.0323
Entamoeba histolytica hypothetical protein 0.0067 0.0231 0.6471
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0047 0.0086 0.0063
Plasmodium falciparum JmjC domain-containing protein, putative 0.0084 0.0353 0.0879
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0078 0.0126
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0211 0.1275 0.1403
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0197 0.0502
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0084 0.0353 0.0364
Trypanosoma brucei metacaspase MCA3 0.0478 0.3208 1
Toxoplasma gondii beta-1 tubulin, putative 0.0049 0.0102 0.0204
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus granulosus snurportin 1 0.0665 0.4566 0.5113
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Trypanosoma cruzi cruzipain precursor, putative 0.0075 0.029 0.0796
Plasmodium vivax JmjC domain containing protein 0.0084 0.0353 0.0879
Brugia malayi bHLH-PAS transcription factor 0.0117 0.0594 0.0924
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.034 0.0954
Brugia malayi Guanylyl cyclase protein 23 0.0069 0.0245 0.0381
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0047 0.0086 0.0152
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Mycobacterium ulcerans short chain dehydrogenase 0.0058 0.0164 0.0417
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus granulosus lysine specific demethylase 6a 0.0084 0.0353 0.0364
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.014 0.0199
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Onchocerca volvulus 0.0445 0.297 0.3401
Echinococcus granulosus FTZ F1 alpha 0.0447 0.2987 0.3334
Echinococcus multilocularis JmjC domain containing protein 4 0.0084 0.0353 0.0364
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0198 0.1177 0.1294
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Schistosoma mansoni jumonji domain containing protein 0.0084 0.0353 0.0324
Trypanosoma brucei Metacaspase-4 0.0478 0.3208 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0447 0.2987 0.3422
Brugia malayi jmjC domain containing protein 0.0314 0.2023 0.3145
Echinococcus multilocularis geminin 0.054 0.3657 0.4089
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0041 0.0043 0.0018
Brugia malayi ecdysteroid receptor 0.0447 0.2987 0.4644
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0447 0.2987 0.4644
Loa Loa (eye worm) hypothetical protein 0.0478 0.3208 0.3716
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Brugia malayi nuclear receptor NHR-88 0.0211 0.1275 0.1981
Loa Loa (eye worm) TK/EGFR protein kinase 0.0191 0.1129 0.1279
Echinococcus multilocularis lysine specific demethylase 5A 0.0314 0.2023 0.2247
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0466 0.3119 0.3483
Brugia malayi glutathione reductase 0.0052 0.0119 0.0186
Leishmania major 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus granulosus glutamate receptor 2 0.0067 0.0231 0.0226
Loa Loa (eye worm) glutamate receptor 1 0.0131 0.0692 0.0767
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Brugia malayi hypothetical protein 0.0445 0.297 0.4617
Leishmania major protein kinase, putative 0.0045 0.0073 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0447 0.2987 0.4644
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.1125 0.1257
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Plasmodium vivax importin-beta 2, putative 0.0062 0.0197 0.0381
Echinococcus granulosus importin subunit beta 1 0.0062 0.0197 0.0188
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.1228 0.8648 1
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis nmda type glutamate receptor 0.0466 0.3119 0.3483
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Loa Loa (eye worm) glutathione reductase 0.0052 0.0119 0.0096
Echinococcus granulosus caspase 0.1263 0.89 1
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Echinococcus granulosus glutamate receptor 2 0.0198 0.1177 0.1294
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0043 0.0018
Schistosoma mansoni glutamate receptor kainate 0.0131 0.0692 0.0664
Echinococcus granulosus metabotropic glutamate receptor 5 0.0067 0.0231 0.0226
Echinococcus granulosus beta LACTamase domain containing family member 0.019 0.1125 0.1234
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.052
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0067 0.0231 0.0358
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Echinococcus granulosus beta tubulin 0.0049 0.0102 0.0082
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.1125 0.1098
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.046 0.3076 0.3434
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0447 0.2987 0.3458
Leishmania major hypothetical protein, conserved 0.019 0.1125 0.3429
Schistosoma mansoni tyrosine kinase 0.0062 0.0192 0.0163
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.1125 0.3429
Brugia malayi hypothetical protein 0.0531 0.3594 0.5587
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0236 0.1458 0.161
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0157 0.0884 0.2672
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0103 0.0492 0.0521
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0047 0.0086 0.0159
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0047 0.0086 0.0152
Brugia malayi hypothetical protein 0.0211 0.1275 0.1981
Schistosoma mansoni aryl hydrocarbon receptor 0.0158 0.0892 0.0865
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0086 0.0027
Echinococcus granulosus Nuclear hormone receptor HR96 0.0211 0.1275 0.1403
Mycobacterium ulcerans ketoacyl reductase 0.0047 0.0086 0.0159
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0038 0.0009
Brugia malayi Inositol-1 0.004 0.0038 0.0058
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0131 0.0692 0.0746
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Echinococcus granulosus peptidase Clp S14 family 0.0161 0.0912 0.0994
Onchocerca volvulus 0.0047 0.0086 0.0049
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0047 0.0086 0.0092
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.019 0.1125 0.3429
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0067 0.0231 0.0226
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Loa Loa (eye worm) hypothetical protein 0.0636 0.4357 0.5063
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0335 0.2172 0.7026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0403 0.2669 0.8661
Schistosoma mansoni peptidase Clp (S14 family) 0.0246 0.1525 0.15
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Brugia malayi Nuclear hormone receptor-like 1 0.0447 0.2987 0.4644
Echinococcus multilocularis retinol dehydrogenase 11 0.0047 0.0086 0.0063
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.1125 0.3429
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.026 0.1628 0.1802
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Schistosoma mansoni metabotropic glutamate receptor 0.0067 0.0231 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0447 0.2987 0.3458
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0047 0.0086 0.1802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0447 0.2987 0.3458
Brugia malayi beta-tubulin, identical 0.0049 0.0102 0.0159
Brugia malayi hypothetical protein 0.0047 0.0086 0.0133
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0236 0.1458 0.1432
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0047 0.0086 0.1802
Schistosoma mansoni tyrosine kinase 0.0103 0.0492 0.0463
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0335 0.2172 0.2532
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1177 0.1294
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0007
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6433
Loa Loa (eye worm) TK/INSR protein kinase 0.0062 0.0192 0.0181
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0067 0.0231 0.0226
Brugia malayi hypoxia-induced factor 1 0.049 0.3295 0.5123
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0102 0.0204
Echinococcus granulosus beta tubulin 0.0049 0.0102 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0478 0.3208 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.037 0.2426 0.2701
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.0369
Onchocerca volvulus 0.0047 0.0086 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.046 0.3076 1
Brugia malayi orphan nuclear receptor NR2E1 0.0211 0.1275 0.1981
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0205
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.01 0.0468 0.0505
Brugia malayi hypothetical protein 0.0067 0.0231 0.0358
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0047 0.0086 0.052
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0246 0.1525 1
Echinococcus granulosus hypothetical protein 0.0047 0.0086 0.0063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Mycobacterium ulcerans esterase/lipase LipP 0.019 0.1125 0.3578
Trypanosoma cruzi metacaspase, putative 0.0478 0.3208 1
Schistosoma mansoni tyrosine kinase 0.0209 0.1263 0.1237
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Brugia malayi hypothetical protein 0.0636 0.4357 0.6774
Onchocerca volvulus 0.019 0.1125 0.1257
Schistosoma mansoni caspase-7 (C14 family) 0.1263 0.89 0.8897
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Leishmania major short chain dehydrogenase-like protein 0.0047 0.0086 0.0152
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4897
Mycobacterium tuberculosis Probable reductase 0.0118 0.0599 0.0692
Toxoplasma gondii carbonyl reductase 1, putative 0.0047 0.0086 0.0152
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0047 0.0086 0.0063
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma brucei oxidoreductase-like protein 0.0047 0.0086 0.0152
Echinococcus granulosus lysosomal alpha glucosidase 0.037 0.2426 0.2701
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0447 0.2987 0.4644
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0119 0.0134
Schistosoma mansoni importin beta-1 0.0062 0.0197 0.0167
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.052
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0086 0.0152
Brugia malayi Furin-like cysteine rich region family protein 0.0191 0.1129 0.1755
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Schistosoma mansoni nuclear hormone receptor 0.0447 0.2987 0.2966
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Trypanosoma cruzi beta tubulin, putative 0.0049 0.0102 0.0204
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0084 0.0353 0.0364
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Loa Loa (eye worm) dehydrogenase 0.0047 0.0086 0.0057
Echinococcus granulosus WW domain containing oxidoreductase 0.0047 0.0086 0.0063
Schistosoma mansoni aldehyde dehydrogenase 0.046 0.3076 0.3055
Brugia malayi hypothetical protein 0.0236 0.1458 0.2267
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.029 0.1848 0.2872
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Echinococcus granulosus nuclear receptor nhr 48 0.0211 0.1275 0.1403
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0058 0.0164 0.1037
Leishmania major quinonoid dihydropteridine reductase 0.0047 0.0086 0.0152
Brugia malayi Nuclear hormone receptor-like 1 0.0236 0.1458 0.2267
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni tyrosine kinase 0.0217 0.1319 0.1293
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Echinococcus multilocularis jumonji domain containing 1A 0.0084 0.0353 0.0364
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0236 0.1458 0.1665
Echinococcus granulosus caspase 2 0.0923 0.6433 0.7218
Brugia malayi nuclear receptor NHR-67 0.0211 0.1275 0.1981
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Mycobacterium tuberculosis Probable lipase LipE 0.019 0.1125 0.1307
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4897
Echinococcus granulosus carbonyl reductase 1 0.0047 0.0086 0.0063
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Onchocerca volvulus 0.0047 0.0086 0.0049
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0078 0.0054
Brugia malayi Nuclear hormone receptor E75 0.0211 0.1275 0.1981
Schistosoma mansoni alpha-glucosidase 0.0318 0.2053 0.2029
Loa Loa (eye worm) hypothetical protein 0.0068 0.024 0.0237
Mycobacterium tuberculosis Probable conserved lipoprotein 0.019 0.1125 0.1307
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0131 0.0692 0.0746
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0235 0.0365
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0078 0.0054
Entamoeba histolytica hypothetical protein, conserved 0.0047 0.0086 0.1802
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0047 0.0086 0.0159
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0102 0.0204
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0447 0.2987 0.4644
Echinococcus multilocularis beta tubulin 0.0049 0.0102 0.0082
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni glutamate receptor AMPA 0.0131 0.0692 0.0664
Leishmania major extracellular receptor, putative 0.0067 0.0231 0.0609
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0235 0.0231
Brugia malayi jmjC domain containing protein 0.0084 0.0353 0.0548
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0118 0.0599 0.0692
Schistosoma mansoni tyrosine kinase 0.0069 0.0245 0.0216
Loa Loa (eye worm) hypothetical protein 0.019 0.1125 0.1274
Brugia malayi RNA, U transporter 1 0.0177 0.1029 0.16
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0447 0.2987 0.2966
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Echinococcus multilocularis glutamate receptor 2 0.0131 0.0692 0.0746
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0211 0.1275 0.1403
Brugia malayi nuclear receptor NHR-88 0.0447 0.2987 0.4644
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Leishmania major short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0478 0.3208 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Toxoplasma gondii beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.1263 0.89 1
Echinococcus granulosus lysine specific demethylase 5A 0.0314 0.2023 0.2247
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0086 0.0063
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0157 0.0884 0.0993
Echinococcus granulosus ecdysone induced protein 78C 0.0447 0.2987 0.3334
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Probable oxidoreductase 0.038 0.2502 0.2918
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0111 0.0233
Mycobacterium ulcerans oxidoreductase 0.0047 0.0086 0.0159
Loa Loa (eye worm) beta-lactamase 0.019 0.1125 0.1274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Giardia lamblia Reductase, putative 0.0047 0.0086 0.3356
Entamoeba histolytica tubulin family protein 0.0049 0.0102 0.2332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0047 0.0086 0.0049
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.034 0.035
Schistosoma mansoni jumonji/arid domain-containing protein 0.0314 0.2023 0.1999
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.1125 0.1098
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0447 0.2987 0.4644
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Loa Loa (eye worm) hypothetical protein 0.0923 0.6433 0.7496
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.014 0.0323
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0395 0.2606 0.304
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Mycobacterium ulcerans short-chain type oxidoreductase 0.0047 0.0086 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Leishmania major metacaspase, putative 0.0478 0.3208 1
Echinococcus granulosus retinol dehydrogenase 11 0.0047 0.0086 0.0063
Echinococcus multilocularis carbonyl reductase 1 0.0047 0.0086 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1848 0.571
Trichomonas vaginalis tubulin beta chain, putative 0.0049 0.0102 0.0204
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0043 0.0018
Toxoplasma gondii oxidoreductase, putative 0.0047 0.0086 0.0152
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.4625
Echinococcus granulosus muscleblind protein 0.067 0.4602 0.5154
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0047 0.0086 0.0133
Trypanosoma brucei short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Leishmania major cathepsin L-like protease 0.0075 0.029 0.0796
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Leishmania major trypanothione reductase 0.0052 0.0119 0.0258
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0131 0.0692 0.0746
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0047 0.0086 0.0092
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Echinococcus granulosus nmda type glutamate receptor 0.0067 0.0231 0.0226
Echinococcus granulosus epidermal growth factor receptor 0.0191 0.1129 0.1239
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0211 0.1275 0.1248
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0092
Brugia malayi oxidoreductase 0.0047 0.0086 0.0133
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0246 0.1525 0.1686
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0056
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0403 0.2669 0.4149
Onchocerca volvulus 0.0069 0.0245 0.0235
Loa Loa (eye worm) hypothetical protein 0.0445 0.297 0.3437
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.019 0.1125 0.1307
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0043 0.0018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.034 0.0954
Schistosoma mansoni metabotropic glutamate receptor 0.0067 0.0231 0.0201
Echinococcus granulosus aryl hydrocarbon receptor 0.0041 0.0043 0.0015
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Echinococcus granulosus atrial natriuretic peptide receptor 0.0067 0.0231 0.0226
Mycobacterium ulcerans dehydrogenase/reductase 0.0047 0.0086 0.0159
Echinococcus multilocularis insulin receptor 0.0062 0.0192 0.0183
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0447 0.2987 0.2966
Echinococcus granulosus single minded 2 0.0117 0.0594 0.0636
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0447 0.2987 0.2966
Echinococcus multilocularis phd:f box containing protein 0.0084 0.0353 0.0364
Brugia malayi Receptor family ligand binding region containing protein 0.0067 0.0231 0.0358
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Echinococcus multilocularis oxidoreductase 0.0047 0.0086 0.0063
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0102 0.0076
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0152
Mycobacterium leprae Possible regulatory protein 0.0041 0.0043 0.024
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0067 0.0231 0.0226
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0047 0.0086 0.0092
Loa Loa (eye worm) hypothetical protein 0.0069 0.0245 0.0244
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni tyrosine kinase 0.0101 0.0477 0.0448
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.014 0.0199
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Onchocerca volvulus 0.0117 0.0594 0.064
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.034 0.0954
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1125 0.3429
Brugia malayi PAS domain containing protein 0.0158 0.0892 0.1387
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Echinococcus granulosus tubulin beta 1 chain 0.0049 0.0102 0.0082
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0161 0.0912 0.1058
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0086 0.0092
Echinococcus multilocularis conserved hypothetical protein 0.0047 0.0086 0.0063
Brugia malayi dehydrogenases, short chain protein 2 0.0047 0.0086 0.0133
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi metabotropic glutamate receptor type 2 0.0067 0.0231 0.0358
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0447 0.2987 0.3334
Trypanosoma brucei metacaspase 0.0478 0.3208 1
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Brugia malayi nuclear hormone receptor family member odr-7 0.0211 0.1275 0.1981
Brugia malayi jmjC domain containing protein 0.0314 0.2023 0.3145
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0131 0.0692 0.0746
Brugia malayi tailless protein 0.0211 0.1275 0.1981
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0447 0.2987 0.3458
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0447 0.2987 0.3334
Loa Loa (eye worm) hypothetical protein 0.0531 0.3594 0.4168
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1177 0.1294
Brugia malayi dehydrogenases, short chain protein 9 0.0047 0.0086 0.0133
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.034 0.0954
Echinococcus granulosus retinol dehydrogenase 11 0.0047 0.0086 0.0063
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Echinococcus granulosus caspase 8 0.0478 0.3208 0.3583
Echinococcus multilocularis retinol dehydrogenase 13 0.0047 0.0086 0.0063
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Entamoeba histolytica short chain dehydrogenase family protein 0.0047 0.0086 0.1802
Leishmania major protein kinase, putative 0.0041 0.0043 0.0018
Echinococcus multilocularis caspase 2 0.0923 0.6433 0.7218
Echinococcus multilocularis ecdysone induced protein 78C 0.0447 0.2987 0.3334
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0047 0.0086 0.0152
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.034 1
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0047 0.0086 0.0092
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0047 0.0086 0.0152
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.019 0.1125 0.1307
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0447 0.2987 0.4644
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0236 0.1454 0.1605
Loa Loa (eye worm) beta-tubulin 0.0049 0.0102 0.0076
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0047 0.0086 0.0133
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0084 0.0353 0.0994
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0041 0.0043 0.0007
Mycobacterium tuberculosis Probable esterase LipL 0.019 0.1125 0.1307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0468 0.0505
Echinococcus multilocularis caspase 8 0.0478 0.3208 0.3583
Loa Loa (eye worm) oxidoreductase 0.0047 0.0086 0.0057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Loa Loa (eye worm) steroid hormone receptor 0.0447 0.2987 0.3458
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0049 0.0102 0.0082
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Loa Loa (eye worm) transcription factor SMAD2 0.0398 0.2629 0.3037
Echinococcus granulosus epidermal growth factor receptor 0.0103 0.0492 0.0521
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0356 0.2328 0.2685
Entamoeba histolytica Ran family GTPase 0.0046 0.0078 0.1534
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0047 0.0086 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0358 0.0898
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0047 0.0086 0.0057
Loa Loa (eye worm) hypothetical protein 0.067 0.4602 0.535
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0246 0.1525 0.6961
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0078 0.0047
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Schistosoma mansoni nuclear receptor 0.0211 0.1275 0.1248
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.034 0.0954
Brugia malayi Probable ClpP-like protease 0.0246 0.1525 0.2371
Brugia malayi nuclear hormone receptor 0.0211 0.1275 0.1981
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0131 0.0694 0.0804
Echinococcus multilocularis retinol dehydrogenase 11 0.0047 0.0086 0.0063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0314 0.2023 0.1999
Leishmania major dehydrogenase-like protein 0.0047 0.0086 0.0152
Echinococcus multilocularis tyrosine protein kinase shark 0.0217 0.1319 0.1454
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Brugia malayi beta-lactamase 0.019 0.1125 0.1748
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Mycobacterium ulcerans beta-lactamase 0.019 0.1125 0.3578
Loa Loa (eye worm) MH2 domain-containing protein 0.0398 0.2629 0.3037
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0447 0.2987 0.3422
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0041 0.0043 0.0015
Schistosoma mansoni protein phosphatase 2C 0.0084 0.0353 0.0324
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.034 1
Echinococcus multilocularis apoptotic protease activating factor 1 0.0445 0.297 0.3315
Schistosoma mansoni hypothetical protein 0.054 0.3657 0.3638
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0086 0.0159
Toxoplasma gondii hypothetical protein 0.0085 0.0358 0.1012
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0018
Toxoplasma gondii beta-tubulin, putative 0.0049 0.0102 0.0204
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0236 0.1454 0.1428
Loa Loa (eye worm) hypothetical protein 0.0211 0.1275 0.145
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0246 0.1525 0.4625
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0211 0.1275 0.145
Brugia malayi nuclear receptor RXR 0.0236 0.1458 0.2267
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0211 0.1275 0.1431
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0447 0.2987 0.4644
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0447 0.2987 0.2966
Echinococcus granulosus steroid dehydrogenase 0.0047 0.0086 0.0063
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0047 0.0086 0.1802
Onchocerca volvulus 0.0047 0.0086 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.3208 1
Schistosoma mansoni nuclear receptor 0.0211 0.1275 0.1248
Echinococcus multilocularis caspase 0.1263 0.89 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0043 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0447 0.2987 0.3334
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Schistosoma mansoni hypothetical protein 0.0068 0.024 0.021
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0198 0.1177 0.1294
Brugia malayi conserved hypotetical protein 0.0211 0.1275 0.1981
Trypanosoma brucei metacaspase MCA2 0.0478 0.3208 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0069 0.0245 0.0235
Plasmodium falciparum glutathione reductase 0.0052 0.0119 0.0134
Loa Loa (eye worm) hypothetical protein 0.0193 0.1141 0.1293
Loa Loa (eye worm) hypothetical protein 0.0047 0.0086 0.0057
Brugia malayi Dehydrogenases, short chain protein 2 0.0047 0.0086 0.0133
Echinococcus multilocularis transfer RNA-Lys 0.0117 0.0594 0.0636
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0447 0.2987 0.3334
Loa Loa (eye worm) hypothetical protein 0.0447 0.2987 0.3458
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0086 0.0159
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.0353 0.0994
Brugia malayi Steroid receptor seven-up type 2 0.0447 0.2987 0.4644
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0447 0.2987 0.4644
Loa Loa (eye worm) hypothetical protein 0.0067 0.0231 0.0226
Brugia malayi hypothetical protein 0.0211 0.1275 0.1981
Mycobacterium ulcerans hydrolase/amidase 0.0333 0.2161 0.6989
Schistosoma mansoni short chain dehydrogenase 0.0047 0.0086 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.014 0.0323
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0047 0.0086 0.0056
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0447 0.2987 0.2966
Loa Loa (eye worm) hypothetical protein 0.0236 0.1458 0.1665
Schistosoma mansoni hypothetical protein 0.0131 0.0692 0.0664
Onchocerca volvulus 0.019 0.1125 0.1257
Schistosoma mansoni inositol monophosphatase 0.004 0.0038 0.0008
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0047 0.0086 0.0152
Trichomonas vaginalis tubulin gamma chain, putative 0.0049 0.0102 0.0204
Leishmania major short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Mycobacterium leprae conserved hypothetical protein 0.019 0.1125 0.7361
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0047 0.0086 0.0152
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0197 0.0188
Schistosoma mansoni thyroid hormone receptor 0.0447 0.2987 0.2966
Echinococcus multilocularis nuclear receptor nhr 48 0.0211 0.1275 0.1403
Trypanosoma brucei beta tubulin 0.0049 0.0102 0.0204
Schistosoma mansoni glutamate receptor AMPA 0.0131 0.0692 0.0664
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0111 0.0233
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0047 0.0086 0.0159
Onchocerca volvulus 0.0047 0.0086 0.0049
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0403 0.2669 0.2975
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0047 0.0086 0.0152
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0047 0.0086 0.0092
Mycobacterium tuberculosis Conserved protein 0.019 0.1125 0.1307
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0086 0.0133
Leishmania major hypothetical protein, conserved 0.0047 0.0086 0.0152
Plasmodium falciparum metacaspase 1 0.0478 0.3208 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0047 0.0086 0.0027
Loa Loa (eye worm) dehydrogenase 0.0047 0.0086 0.0057
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.019 0.1125 0.1748
Plasmodium vivax hypothetical protein, conserved 0.019 0.1125 0.3345
Echinococcus granulosus phd:f box containing protein 0.0084 0.0353 0.0364
Schistosoma mansoni tyrosine kinase 0.0103 0.0492 0.0463
Schistosoma mansoni protein kinase 0.0069 0.0245 0.0216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0236 0.1458 0.1432
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0102 0.0082
Schistosoma mansoni steroid dehydrogenase 0.0047 0.0086 0.0056
Giardia lamblia Beta tubulin 0.0049 0.0102 1
Schistosoma mansoni phosphatidylserine receptor 0.0084 0.0353 0.0324
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0047 0.0086 0.0063
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.0353 0.0369
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0447 0.2987 0.4644
Loa Loa (eye worm) DR-78 0.0211 0.1275 0.145
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0078 0.012
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0102 0.0082
Trypanosoma brucei glucosidase, putative 0.0082 0.034 0.0954
Entamoeba histolytica hypothetical protein 0.0051 0.0111 0.2624
Leishmania major beta tubulin 0.0049 0.0102 0.0204
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0047 0.0086 0.0092
Trypanosoma cruzi short chain dehydrogenase, putative 0.0047 0.0086 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Schistosoma mansoni tubulin subunit beta 0.0049 0.0102 0.0073
Echinococcus multilocularis thyroid hormone receptor alpha 0.0447 0.2987 0.3334
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.014 0.0199
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0119 0.0096
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.1263 0.89 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0447 0.2987 0.4644
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.029 0.0796
Entamoeba histolytica tubulin family protein 0.0049 0.0102 0.2332
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0193 0.1141 0.1275
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0314 0.2023 0.2247
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0478 0.3208 1
Echinococcus multilocularis nmda type glutamate receptor 0.0067 0.0231 0.0226

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 8 % Binding affinity against human CB2 receptor by using CHO-hCB2 transfected cell membrane [3H]-Win55,212-2 as radioligand at 10 microM ChEMBL. 14521402
Inhibition (binding) = 8 % Inhibition of fatty acid amide hydrolase (FAAH) from rat brain homogenates at 10 microM ChEMBL. 14521402
Inhibition (binding) = 8 % Binding affinity against human CB2 receptor by using CHO-hCB2 transfected cell membrane [3H]-Win55,212-2 as radioligand at 10 microM ChEMBL. 14521402
Inhibition (binding) = 8 % Inhibition of fatty acid amide hydrolase (FAAH) from rat brain homogenates at 10 microM ChEMBL. 14521402
Inhibition (binding) = 8.1 % Percent inhibition of specific binding of [3H]-Win55,212-2 towards human cannabinoid receptor 2 from Chinese hamster ovary cell membranes at the concentration of 10 microM. ChEMBL. 12672243
Inhibition (binding) = 8.1 % Percent inhibition of specific binding of [3H]-Win55,212-2 towards human cannabinoid receptor 2 from Chinese hamster ovary cell membranes at the concentration of 10 microM. ChEMBL. 12672243
Inhibition (functional) = 11 % Tested for percent inhibition of AEA (N-arachidonoylethanolamine) metabolism in rat brain homogenates using [3H]-anandamide as the labeled substrate at 100 microM ChEMBL. 12672243
Inhibition (binding) = 11 % Inhibition of fatty acid amide hydrolase (FAAH) from rat brain homogenates at 100 microM ChEMBL. 14521402
Inhibition (binding) = 11 % Inhibition of fatty acid amide hydrolase (FAAH) from rat brain homogenates at 100 microM ChEMBL. 14521402
Inhibition (binding) = 23 % Inhibition of N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 microM ChEMBL. 14521402
Inhibition (binding) = 23 % Inhibition of N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 microM ChEMBL. 14521402
Inhibition (binding) = 34 % Binding affinity against human Cannabinoid receptor 1 using CHO-hCB1 transfected cell membrane and [3H]-CP55,940 as radioligand at 10 microM ChEMBL. 14521402
Inhibition (binding) = 34 % Binding affinity against human Cannabinoid receptor 1 using CHO-hCB1 transfected cell membrane and [3H]-CP55,940 as radioligand at 10 microM ChEMBL. 14521402
Inhibition (binding) = 34.2 % Percent inhibition of specific binding of [3H]-CP55,940 towards human cannabinoid receptor 1 from Chinese hamster ovary cell membranes at the concentration of 10 microM. ChEMBL. 12672243
Inhibition (binding) = 34.2 % Percent inhibition of specific binding of [3H]-CP55,940 towards human cannabinoid receptor 1 from Chinese hamster ovary cell membranes at the concentration of 10 microM. ChEMBL. 12672243

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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