Detailed information for compound 549554

Basic information

Technical information
  • TDR Targets ID: 549554
  • Name: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hy droxy-2,2-diphenyl-acetate hydrochloride
  • MW: 387.9 | Formula: C22H26ClNO3
  • H donors: 1 H acceptors: 2 LogP: 4.66 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1C2CCC1CC(C2)OC(=O)C(c1ccccc1)(c1ccccc1)O.Cl
  • InChi: 1S/C22H25NO3.ClH/c1-23-18-12-13-19(23)15-20(14-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18-20,25H,12-15H2,1H3;1H
  • InChiKey: KBGDDPWSFYFMKX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-hydroxy-2,2-diphenylacetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride
  • (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2,2-diphenyl-ethanoate hydrochloride
  • 2-hydroxy-2,2-diphenyl-acetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride
  • (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2,2-diphenylacetate hydrochloride
  • glipin
  • 1674-94-8
  • 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, benzilate (ester), hydrochloride
  • 3-Tropyl benzilate hydrochloride
  • 3alpha(1alphaH,5alphaH)-Tropanylbenzilat hydrochlorid
  • Benzilsaeure-tropinester hydrochlorid [German]
  • Spasmo-Inalgon
  • Tropine benzilate hydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0663 0.1254 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0016 0.0047
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0007 0.0005
Onchocerca volvulus 0.0054 0.0075 0.0398
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Giardia lamblia Encystation-specific protease 0.004 0.0047 0.0269
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.018
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0524 0.4115
Loa Loa (eye worm) hypothetical protein 0.0176 0.0311 0.191
Brugia malayi Pre-SET motif family protein 0.0851 0.1618 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.009 0.0088
Brugia malayi Papain family cysteine protease containing protein 0.0215 0.0387 0.2384
Brugia malayi cahepsin L-like non-peptiedase homolog 0.004 0.0047 0.0279
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Schistosoma mansoni lamin 0.0058 0.0083 0.0151
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0038 0.0058
Onchocerca volvulus 0.0019 0.0007 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0482 0.0903 0.0901
Plasmodium falciparum serine repeat antigen 4 0.004 0.0047 0.0342
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0241 0.0388
Echinococcus multilocularis high affinity choline transporter 1 0.0355 0.0657 0.0655
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.018 0.1896
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0249 0.1351
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Echinococcus granulosus lamin dm0 0.0058 0.0083 0.0151
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.001 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0007 0.0005
Trichomonas vaginalis esterase, putative 0.0035 0.0038 0.0206
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Loa Loa (eye worm) transcription factor SMAD2 0.0387 0.0719 0.444
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.0057 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.0057 0.0086
Entamoeba histolytica papain family cysteine protease domain containing protein 0.004 0.0047 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Brugia malayi Calcitonin receptor-like protein seb-1 0.0671 0.127 0.7849
Loa Loa (eye worm) hypothetical protein 0.0123 0.0209 0.1281
Plasmodium vivax serine-repeat antigen (SERA), putative 0.004 0.0047 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0048 0.0282
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0076 0.0118 0.0116
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.018 0.0331
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.018 0.0292
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0048 0.0085
Plasmodium falciparum epoxide hydrolase 1 0.0037 0.0042 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0111 0.0202
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0048 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0048 0.0282
Plasmodium falciparum cysteine proteinase falcipain 1 0.0111 0.0185 0.1445
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0201 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Entamoeba histolytica cysteine proteinase 2 0.0111 0.0185 0.1405
Entamoeba histolytica cysteine proteinase, putative 0.0215 0.0387 0.3031
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Trypanosoma cruzi cysteine proteinase, putative 0.0111 0.0185 0.1381
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0663 0.1254 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.004 0.0047 0.0342
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Brugia malayi hypothetical protein 0.0319 0.0587 0.3621
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.004 0.0047 0.0256
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0108 0.076
Echinococcus granulosus microtubule associated protein 2 0.2798 0.5388 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0212 0.0382 0.0705
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0048 0.0282
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0014 0.0075
Plasmodium vivax unspecified product 0.0071 0.0108 0.0829
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Echinococcus granulosus cathepsin b 0.004 0.0047 0.0084
Schistosoma mansoni cathepsin F (C01 family) 0.0144 0.0249 0.0459
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0046 0.0082
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Loa Loa (eye worm) hypothetical protein 0.0062 0.009 0.0544
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.004 0.0047 0.0342
Trypanosoma brucei polo-like protein kinase 0.0094 0.0151 0.1205
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0016 0.0022
Onchocerca volvulus 0.0146 0.0253 0.136
Plasmodium vivax SET domain protein, putative 0.0123 0.0209 0.1637
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.001 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0185 0.1003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0061 0.033
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Schistosoma mansoni cpg binding protein 0.0072 0.0109 0.0199
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0403 0.0658
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0048 0.0282
Loa Loa (eye worm) hypothetical protein 0.0355 0.0657 0.4052
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Trypanosoma brucei trypanothione reductase 0.0129 0.022 0.1756
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.3161 0.6092 1
Brugia malayi phosphofructokinase 0.0108 0.018 0.1103
Onchocerca volvulus 0.003 0.0029 0.0147
Schistosoma mansoni lamin 0.0058 0.0083 0.0151
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.001 0.0015
Echinococcus granulosus thioredoxin glutathione reductase 0.013 0.0221 0.0407
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0167 0.102
Echinococcus multilocularis lamin 0.0058 0.0083 0.0081
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0014 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0046 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0083 0.0502
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0016 0.0047
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Echinococcus granulosus cpg binding protein 0.0072 0.0109 0.0199
Entamoeba histolytica cysteine proteinase, putative 0.0215 0.0387 0.3031
Loa Loa (eye worm) hypothetical protein 0.0498 0.0934 0.5768
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0075 0.0454
Echinococcus multilocularis solute carrier family 5 0.0039 0.0046 0.0044
Brugia malayi G-protein alpha subunit 0.0021 0.001 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0311 0.2394
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.0057 0.0348
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Loa Loa (eye worm) cysteine protease 0.0215 0.0387 0.2384
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Echinococcus multilocularis muscleblind protein 0.0146 0.0253 0.0251
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0048 0.0085
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0075 0.0136
Echinococcus multilocularis cysteine protease 0.0215 0.0387 0.0385
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.009 0.0088
Echinococcus multilocularis cathepsin b 0.004 0.0047 0.0045
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0048 0.0282
Onchocerca volvulus 0.0035 0.0038 0.0195
Schistosoma mansoni inositol transporter 0.0039 0.0046 0.0082
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0192 0.0342 0.034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.0057 0.042
Brugia malayi Inositol-1 0.0078 0.0122 0.0744
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.018 0.0331
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0671 0.127 0.7849
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0048 0.0046
Echinococcus granulosus tumor protein p63 0.0997 0.19 0.3524
Echinococcus granulosus cathepsin L 0.0111 0.0185 0.034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0671 0.127 0.7849
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.3161 0.6092 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0215 0.0387 0.0385
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0212 0.0382 0.038
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Schistosoma mansoni kinase 0.0048 0.0063 0.0114
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0007 0.0026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0057 0.0348
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0212 0.0382 0.0705
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0075 0.0136
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0089 0.0537
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Schistosoma mansoni nuclear receptor 0.0019 0.0007 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0007 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0048 0.0282
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0048 0.0282
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.045 0.0841 0.1558
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0108 0.0656
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0008
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0011 0.0017
Brugia malayi ecdysteroid receptor 0.004 0.0048 0.0282
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0015
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi MH1 domain containing protein 0.0026 0.0021 0.0119
Brugia malayi Sodium:neurotransmitter symporter family protein 0.045 0.0841 0.5193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0128
Brugia malayi TAR-binding protein 0.0061 0.0089 0.0537
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0021 0.0119
Brugia malayi Cathepsin L-like cysteine proteinase 0.0144 0.0249 0.1531
Echinococcus multilocularis sodium and chloride dependent glycine 0.0076 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0192 0.0342 0.2701
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.001 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Loa Loa (eye worm) hypothetical protein 0.0663 0.1254 0.7746
Mycobacterium ulcerans beta-lactamase 0.0035 0.0038 0.0055
Echinococcus granulosus cathepsin l cysteine peptidase 0.0215 0.0387 0.0715
Schistosoma mansoni sodium/chloride dependent transporter 0.045 0.0841 0.1558
Toxoplasma gondii histone lysine methyltransferase SET1 0.0133 0.0228 0.1638
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0061 0.033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Plasmodium falciparum glutathione reductase 0.0129 0.022 0.1729
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus granulosus abhydrolase domain containing protein 0.0037 0.0042 0.0074
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Onchocerca volvulus 0.0215 0.0387 0.209
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Trypanosoma cruzi cysteine proteinase, putative 0.0111 0.0185 0.1381
Trypanosoma cruzi major cysteine proteinase, putative 0.004 0.0047 0.0269
Brugia malayi cathepsin L-like precursor 0.0144 0.0249 0.1531
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Echinococcus granulosus intermediate filament protein 0.0058 0.0083 0.0151
Schistosoma mansoni hypothetical protein 0.033 0.0609 0.1128
Treponema pallidum sodium- and chloride- dependent transporter 0.045 0.0841 0.6636
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0048 0.0046
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Echinococcus granulosus cathepsin L 0.004 0.0047 0.0084
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0048 0.0085
Echinococcus granulosus muscleblind protein 0.0146 0.0253 0.0466
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0038 0.0223
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0046 0.0082
Schistosoma mansoni cpg binding protein 0.0072 0.0109 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Onchocerca volvulus 0.0215 0.0387 0.209
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi nuclear receptor NHR-67 0.0019 0.0007 0.0029
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0076 0.0118 0.0116
Loa Loa (eye worm) RNA binding protein 0.0061 0.0089 0.0537
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.0209 0.1484
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0295 0.0541 0.0884
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.0057 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0122 0.0108
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0011 0.0009
Entamoeba histolytica papain family cysteine protease domain containing protein 0.004 0.0047 0.0297
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0141
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.004 0.0047 0.0084
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0037
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0007 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Leishmania major cysteine peptidase A (CPA) 0.0215 0.0387 0.3011
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.0057 0.034
Echinococcus granulosus survival motor neuron protein 1 0.0498 0.0934 0.173
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0012 0.001
Entamoeba histolytica cysteine protease, putative 0.0215 0.0387 0.3031
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0149 0.0258 0.0475
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0122 0.09
Schistosoma mansoni cathepsin F (C01 family) 0.0215 0.0387 0.0715
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Trypanosoma cruzi cysteine peptidase, putative 0.0111 0.0185 0.1381
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0192 0.0342 0.0631
Plasmodium falciparum amino acid transporter, putative 0.0076 0.0118 0.0909
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0057 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.018 0.125
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0046 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0278 0.0509 0.3137
Brugia malayi cathepsin L-like cysteine proteinase 0.004 0.0047 0.0279
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0038 0.0253
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0048 0.0046
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0076 0.0118 0.0116
Brugia malayi Latrophilin receptor protein 2 0.0212 0.0382 0.2349
Schistosoma mansoni intermediate filament proteins 0.0058 0.0083 0.0151
Plasmodium falciparum glutathione reductase 0.0045 0.0057 0.042
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0192 0.0342 0.2701
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.004 0.0047 0.0342
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0215 0.0387 0.2384
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0014 0.0012
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.004 0.0047 0.0084
Trypanosoma brucei PAB1-binding protein , putative 0.0176 0.0311 0.2477
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni zinc finger protein 0.0019 0.0007 0.0009
Echinococcus granulosus dna polymerase kappa 0.0023 0.0014 0.0022
Brugia malayi hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus cathepsin b 0.004 0.0047 0.0084
Trypanosoma cruzi cruzipain precursor, putative 0.0215 0.0387 0.3011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0027 0.0146
Loa Loa (eye worm) hypothetical protein 0.0671 0.127 0.7849
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0192 0.0342 0.0631
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.0209 0.0384
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0038 0.0223
Plasmodium falciparum serine repeat antigen 9 0.004 0.0047 0.0342
Plasmodium falciparum cysteine proteinase falcipain 3 0.0215 0.0387 0.3064
Plasmodium falciparum serine repeat antigen 3 0.004 0.0047 0.0342
Giardia lamblia Kinase, PLK 0.0094 0.0151 0.1109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0122 0.0662
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0075 0.0073
Schistosoma mansoni hypothetical protein 0.0523 0.0982 0.182
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.0151 0.0924
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.0057 0.0309
Brugia malayi Thioredoxin reductase 0.0129 0.022 0.1352
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0663 0.1254 0.7746
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0048 0.0085
Onchocerca volvulus 0.0039 0.0046 0.0238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0027 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.004 0.0047 0.0084
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0015
Brugia malayi hydrolase, alpha/beta fold family protein 0.0037 0.0042 0.0247
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0038 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.004 0.0047 0.0256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0215 0.0387 0.3064
Leishmania major hypothetical protein, conserved 0.0037 0.0042 0.0227
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Brugia malayi hypothetical protein 0.0021 0.0011 0.0056
Plasmodium vivax unspecified product 0.004 0.0047 0.0342
Brugia malayi Cathepsin L-like precursor 0.0071 0.0108 0.0656
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Onchocerca volvulus 0.0215 0.0387 0.209
Loa Loa (eye worm) hypothetical protein 0.0459 0.0859 0.5303
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0201 0.037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0482 0.0903 0.5573
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Schistosoma mansoni hypothetical protein 0.0073 0.0111 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Schistosoma mansoni inositol monophosphatase 0.0078 0.0122 0.0223
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0151 0.1109
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0034 0.0197
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Echinococcus multilocularis cysteine protease 0.0215 0.0387 0.0385
Echinococcus granulosus cathepsin L cysteine protease 0.0111 0.0185 0.034
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.001 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0851 0.1618 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.0057 0.0309
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0048 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0482 0.0903 0.1672
Loa Loa (eye worm) papain family cysteine protease containing protein 0.004 0.0047 0.0279
Toxoplasma gondii preprocathepsin c precursor, putative 0.004 0.0047 0.0165
Loa Loa (eye worm) MBCTL1 0.0062 0.009 0.0544
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.009 0.0544
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0007 0.0009
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0021 0.0119
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0046 0.0044
Loa Loa (eye worm) inositol-1 0.0078 0.0122 0.0744
Loa Loa (eye worm) glutathione reductase 0.0129 0.022 0.1352
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0048 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0215 0.0387 0.3064
Schistosoma mansoni coup transcription factor 0.004 0.0048 0.0085
Onchocerca volvulus 0.0215 0.0387 0.209
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.001 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0076 0.0118 0.0718
Brugia malayi Pre-SET motif family protein 0.0123 0.0209 0.1281
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0122 0.0776
Toxoplasma gondii cathepsin B 0.004 0.0047 0.0165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0111 0.0185 0.1474
Plasmodium vivax vivapain-3 0.0111 0.0185 0.1445
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0007 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0038 0.0301
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0025 0.0023
Echinococcus multilocularis survival motor neuron protein 1 0.0498 0.0934 0.0932
Echinococcus multilocularis GPCR, family 2 0.0212 0.0382 0.038
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0471 0.0882 1
Schistosoma mansoni inositol transporter 0.0039 0.0046 0.0082
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0012 0.001
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0021 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Leishmania major trypanothione reductase 0.0129 0.022 0.1666
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0014 0.0022
Onchocerca volvulus 0.0058 0.0083 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.0151 0.1134
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0038 0.0058
Echinococcus granulosus mitogen activated protein kinase 3 0.0119 0.0201 0.037
Onchocerca volvulus 0.0123 0.0209 0.1123
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.018 0.0289
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.0201 0.0326
Echinococcus granulosus sodium and chloride dependent glycine 0.0076 0.0118 0.0215
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0038 0.0055
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0075 0.0136
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Plasmodium falciparum serine repeat antigen 1 0.004 0.0047 0.0342
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0014 0.0012
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.001 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Entamoeba histolytica hypothetical protein 0.004 0.0047 0.0297
Brugia malayi hypothetical protein 0.0021 0.001 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Brugia malayi MH2 domain containing protein 0.0026 0.0021 0.0119
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0311 0.2394
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0524 0.4131
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0048 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0048 0.0282
Toxoplasma gondii cathepsin CPC2 0.004 0.0047 0.0165
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Echinococcus multilocularis cathepsin L 0.0111 0.0185 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0048 0.0282
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Schistosoma mansoni inositol monophosphatase 0.0078 0.0122 0.0223
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.004 0.0047 0.0342
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0241 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0295 0.0541 0.0884
Echinococcus granulosus sodium and chloride dependent glycine 0.0076 0.0118 0.0215
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0209 0.0384
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0048 0.0085
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0663 0.1254 0.2324
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0192 0.0342 0.1853
Loa Loa (eye worm) hypothetical protein 0.0319 0.0587 0.3621
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0048 0.0282
Echinococcus granulosus expressed protein 0.0021 0.001 0.0015
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0192 0.0342 0.1853
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Mycobacterium ulcerans hypothetical protein 0.0035 0.0038 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0206
Echinococcus granulosus FTZ F1 alpha 0.004 0.0048 0.0085
Onchocerca volvulus 0.004 0.0047 0.0245
Loa Loa (eye worm) ctsf protein 0.0215 0.0387 0.2384
Schistosoma mansoni DNA polymerase eta 0.0023 0.0014 0.0022
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.004 0.0047 0.0342
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0079 0.0123 0.0121
Schistosoma mansoni hypothetical protein 0.0523 0.0982 0.182
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0048 0.0085
Trypanosoma cruzi trypanothione reductase, putative 0.0129 0.022 0.1666
Plasmodium falciparum thioredoxin reductase 0.0129 0.022 0.1729
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.002 0.0018
Brugia malayi MH2 domain containing protein 0.0387 0.0719 0.444
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Loa Loa (eye worm) DR-78 0.0019 0.0007 0.0029
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0014 0.0029
Echinococcus granulosus serotonin transporter 0.045 0.0841 0.1558
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0016 0.0019
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0012 0.0018
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.004 0.0047 0.0342
Schistosoma mansoni hydrolase 0.0037 0.0042 0.0074
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0007 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0118 0.0215
Onchocerca volvulus 0.004 0.0048 0.0247
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0055
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Onchocerca volvulus 0.0215 0.0387 0.209
Mycobacterium ulcerans lipase LipD 0.0035 0.0038 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0048 0.0282
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.0057 0.0086
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.0057 0.042
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0048 0.0085
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.004 0.0047 0.0269
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0021 0.001 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Leishmania major hypothetical protein, conserved 0.0176 0.0311 0.2394
Loa Loa (eye worm) CXXC zinc finger family protein 0.0068 0.0102 0.0617
Schistosoma mansoni smad 0.0026 0.0021 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.0151 0.0924
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0048 0.0046
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.004 0.0047 0.0084
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0019 0.0106
Plasmodium vivax ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.3161 0.6092 1
Brugia malayi RNA binding protein 0.0061 0.0089 0.0537
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Onchocerca volvulus 0.0024 0.0016 0.0076
Schistosoma mansoni thyroid hormone receptor 0.004 0.0048 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.0201 0.1511
Onchocerca volvulus 0.0215 0.0387 0.209
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.004 0.0047 0.0342
Echinococcus granulosus smad 0.0026 0.0021 0.0036
Brugia malayi fibroinase precursor 0.004 0.0047 0.0279
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0027 0.0106
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.018 0.1103
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.004 0.0047 0.0269
Brugia malayi hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0015
Echinococcus granulosus high affinity choline transporter 1 0.0355 0.0657 0.1216
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Toxoplasma gondii thioredoxin reductase 0.0129 0.022 0.1577
Toxoplasma gondii cathepsin CPL 0.0215 0.0387 0.2936
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0663 0.1254 1
Trypanosoma cruzi major cysteine proteinase, putative 0.004 0.0047 0.0269
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0119 0.0201 0.1603
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0452
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0079 0.0123 0.0225
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.0201 0.142
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Mycobacterium tuberculosis Probable dehydrogenase 0.0295 0.0541 0.0884
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0108 0.076
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0083 0.0502
Echinococcus multilocularis cathepsin L cysteine protease 0.0215 0.0387 0.0385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0047 0.0256
Echinococcus multilocularis thioredoxin glutathione reductase 0.013 0.0221 0.0219
Giardia lamblia Cathepsin L-like protease 0.004 0.0047 0.0269
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1555
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0215 0.0387 0.2384
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Echinococcus multilocularis smad 0.0026 0.0021 0.0019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0117 0.0197 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0048 0.0282
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.004 0.0047 0.0342
Plasmodium falciparum serine repeat antigen 8 0.004 0.0047 0.0342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.0151 0.0149
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0007 0.0029
Loa Loa (eye worm) Smad1 0.0026 0.0021 0.0119
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0046 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus multilocularis expressed protein 0.0021 0.001 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0075 0.0136
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0295 0.0541 0.0884
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0048 0.0046
Loa Loa (eye worm) phosphofructokinase 0.0108 0.018 0.1103
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 0.6795
Plasmodium vivax vivapain-2 0.0215 0.0387 0.3064
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Brugia malayi cathepsin F-like cysteine proteinase 0.004 0.0047 0.0279
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0048 0.0247
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0106 0.017
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656
Schistosoma mansoni nuclear receptor 0.0019 0.0007 0.0009
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0076 0.0118 0.0215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0524 0.4052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0007 0.0029
Trichomonas vaginalis set domain proteins, putative 0.0968 0.1845 1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0021 0.001 0.0056
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0015
Onchocerca volvulus 0.0102 0.0167 0.0894
Schistosoma mansoni hypothetical protein 0.0079 0.0123 0.0225
Brugia malayi conserved hypotetical protein 0.0019 0.0007 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0014 0.0108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0057 0.0348
Giardia lamblia Kinase, CMGC MAPK 0.0119 0.0201 0.1511
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.0144 0.0249 0.1923
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.004 0.0047 0.0342
Mycobacterium tuberculosis Probable reductase 0.0295 0.0541 0.0884
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0249 0.1351
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Brugia malayi hypothetical protein 0.0176 0.0311 0.191
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0021 0.001 0.0056
Toxoplasma gondii cathepsin CPC1 0.004 0.0047 0.0165
Mycobacterium tuberculosis Probable oxidoreductase 0.0328 0.0605 0.0989
Onchocerca volvulus 0.0021 0.001 0.0045
Brugia malayi hypothetical protein 0.0073 0.0111 0.0675
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.0057 0.0452
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0021 0.0036
Trypanosoma brucei protein kinase, putative 0.0119 0.0201 0.1603
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0122 0.012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Giardia lamblia Cathepsin L-like protease 0.004 0.0047 0.0269
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Onchocerca volvulus Cathepsin L homolog 0.0215 0.0387 0.209
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0016 0.0019
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0663 0.1254 0.1252
Loa Loa (eye worm) hypothetical protein 0.0057 0.0081 0.049
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.0057 0.042
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.018 0.0331
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0031 0.0178
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0021 0.001 0.0051
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.0151 0.0277
Loa Loa (eye worm) hypothetical protein 0.0054 0.0075 0.0454
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0223
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0046 0.0044
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0015
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0076 0.0118 0.0187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Schistosoma mansoni microtubule-associated protein tau 0.2798 0.5388 1
Brugia malayi nuclear hormone receptor 0.004 0.0048 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.0151 0.081
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0212 0.0382 0.2349
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0014 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Plasmodium vivax serine-repeat antigen (SERA) 0.004 0.0047 0.0342
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0119 0.0201 0.142
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0007 0.0029
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0038 0.0067
Plasmodium falciparum serine repeat antigen 5 0.004 0.0047 0.0342
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0119 0.0201 0.1233
Onchocerca volvulus Cathepsin L homolog 0.004 0.0047 0.0245
Brugia malayi Cathepsin L-like precursor 0.0144 0.0249 0.1531
Loa Loa (eye worm) hypothetical protein 0.0212 0.0382 0.2349
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0253 0.0251
Plasmodium vivax vivapain-1 0.0111 0.0185 0.1445
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.0057 0.0348
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0007 0.0005
Loa Loa (eye worm) thioredoxin reductase 0.0129 0.022 0.1352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0185 0.1003
Echinococcus multilocularis cathepsin L 0.004 0.0047 0.0045
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.002 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi nuclear receptor RXR 0.0019 0.0007 0.0029
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0102
Brugia malayi hypothetical protein 0.0498 0.0934 0.5768
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0048 0.0046
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0034 0.0197
Onchocerca volvulus 0.0968 0.1845 1
Brugia malayi MH1 domain containing protein 0.0026 0.0021 0.0119
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Echinococcus multilocularis tumor protein p63 0.0997 0.19 0.1898
Loa Loa (eye worm) latrophilin receptor protein 2 0.0212 0.0382 0.2349
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0048 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0046 0.0044
Schistosoma mansoni thyroid hormone receptor 0.004 0.0048 0.0085
Echinococcus granulosus tar DNA binding protein 0.0061 0.0089 0.0161
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.009 0.0163
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Mycobacterium leprae Probable lipase LipE 0.0035 0.0038 0.0253
Trypanosoma cruzi cysteine protease, putative 0.0111 0.0185 0.1381
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0119 0.0201 0.1511
Brugia malayi 6-phosphofructokinase 0.0108 0.018 0.1103
Brugia malayi Cathepsin L-like precursor 0.0144 0.0249 0.1531
Brugia malayi glutathione reductase 0.0129 0.022 0.1352
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0122 0.0223
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0663 0.1254 1
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.0201 0.037
Schistosoma mansoni cpg binding protein 0.0068 0.0102 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Brugia malayi cathepsin Z-like cysteine proteinase 0.004 0.0047 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Schistosoma mansoni hypothetical protein 0.0102 0.0167 0.0306
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.004 0.0047 0.0342
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0663 0.1254 1
Loa Loa (eye worm) serotonin transporter b 0.045 0.0841 0.5193
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0046 0.0082
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0118 0.0909
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0295 0.0541 0.0884
Echinococcus multilocularis musashi 0.0058 0.0083 0.0081
Brugia malayi Smad1 0.0026 0.0021 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Brugia malayi CXXC zinc finger family protein 0.0068 0.0102 0.0617
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0067
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0012 0.0018
Plasmodium vivax unspecified product 0.0111 0.0185 0.1445
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0083 0.0502
Echinococcus multilocularis geminin 0.0523 0.0982 0.098
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Schistosoma mansoni Smad4 0.0026 0.0021 0.0036
Brugia malayi beta-lactamase 0.0035 0.0038 0.0223
Brugia malayi 6-phosphofructokinase 0.0108 0.018 0.1103
Echinococcus granulosus Smad4 0.0026 0.0021 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0482 0.0903 0.1672
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0272
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0048 0.0046
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.009 0.0163
Brugia malayi nuclear receptor NHR-88 0.0019 0.0007 0.0029
Loa Loa (eye worm) fibroinase 0.0215 0.0387 0.2384
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0048 0.0282
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0007 0.0009
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0111 0.0185 0.1381
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Brugia malayi nuclear receptor NHR-88 0.004 0.0048 0.0282
Echinococcus multilocularis microtubule associated protein 2 0.2798 0.5388 0.5387
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.0201 0.0199
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0038 0.0058
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.004 0.0047 0.0269
Plasmodium vivax amine transporter, putative 0.0076 0.0118 0.0909
Echinococcus multilocularis cpg binding protein 0.0072 0.0109 0.0107
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0016 0.0019
Onchocerca volvulus 0.0319 0.0587 0.3175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0007 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Mycobacterium ulcerans hypothetical protein 0.0024 0.0016 0.0019
Brugia malayi GH02984p 0.0355 0.0657 0.4052
Loa Loa (eye worm) histone methyltransferase 0.0025 0.002 0.0109
Loa Loa (eye worm) papain family cysteine protease containing protein 0.004 0.0047 0.0279
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0129 0.022 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0185 0.1133
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0118 0.0215
Brugia malayi cathepsin B-like cysteine proteinase 0.004 0.0047 0.0279
Echinococcus granulosus dna polymerase eta 0.0023 0.0014 0.0022
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.018
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Schistosoma mansoni survival motor neuron protein 0.0102 0.0167 0.0306
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0185 0.1133
Echinococcus granulosus cysteine protease 0.0111 0.0185 0.034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0482 0.0903 0.0901
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0048 0.0247
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0048 0.0046
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Plasmodium falciparum serine repeat antigen 2 0.004 0.0047 0.0342
Echinococcus multilocularis cathepsin b 0.004 0.0047 0.0045
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.0057 0.0244
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.001 0.0051
Onchocerca volvulus 0.0019 0.0007 0.0026
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0663 0.1254 1
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Loa Loa (eye worm) norepinephrine transporter 0.045 0.0841 0.5193
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0215 0.0387 0.0385
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Onchocerca volvulus 0.0035 0.0038 0.0195
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Echinococcus multilocularis mitogen activated protein kinase 0.0119 0.0201 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0241 0.2595
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0111 0.0202
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.004 0.0047 0.0342
Schistosoma mansoni cathepsin s 0.0071 0.0108 0.0197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi intermediate filament protein 0.0058 0.0083 0.0502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0048 0.0085
Echinococcus multilocularis cathepsin L cysteine protease 0.0215 0.0387 0.0385
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0206
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0038 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.004 0.0047 0.0256
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Brugia malayi latrophilin 2 splice variant baaae 0.0459 0.0859 0.5303
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0482 0.0903 0.5573
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.0057 0.0089
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0048 0.0085
Onchocerca volvulus 0.0068 0.0102 0.0541
Leishmania major hypothetical protein, conserved 0.0035 0.0038 0.0195
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0004 0.0003
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0048 0.0282
Plasmodium falciparum phenylalanine--tRNA ligase 0.0192 0.0342 0.2701
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0048 0.0085
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Brugia malayi nuclear receptor RXR 0.0021 0.0011 0.0056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0007 0.0005
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.003 0.0029 0.0231
Brugia malayi cathepsin Z-like cysteine proteinase 0.004 0.0047 0.0279
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0192 0.0342 0.0631
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Plasmodium falciparum serine repeat antigen 7 0.004 0.0047 0.0342
Brugia malayi ecdysone receptor 0.0019 0.0007 0.0029
Onchocerca volvulus 0.0021 0.001 0.0045
Schistosoma mansoni sodium/chloride dependent transporter 0.0076 0.0118 0.0215
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0328 0.0605 0.0989
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus granulosus cathepsin L cysteine proteinase 0.0215 0.0387 0.0715
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0048 0.0085
Schistosoma mansoni cellular tumor antigen P53 0.0146 0.0253 0.0465
Echinococcus multilocularis serotonin transporter 0.045 0.0841 0.0839
Brugia malayi cathepsin F-like cysteine proteinase 0.0071 0.0108 0.0656
Giardia lamblia Hypothetical protein 0.004 0.0047 0.0269
Onchocerca volvulus 0.0035 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0075 0.0073
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0025 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0014 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0151 0.1109
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0007 0.0009
Brugia malayi hypothetical protein 0.0021 0.0011 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0038 0.0055
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0016 0.0019
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0007 0.0029
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus multilocularis abhydrolase domain containing protein 0.0037 0.0042 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Schistosoma mansoni sodium/chloride dependent transporter 0.0078 0.0121 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Loa Loa (eye worm) solute carrier family 6 member 4 0.045 0.0841 0.5193
Schistosoma mansoni cathepsin B (C01 family) 0.004 0.0047 0.0084
Echinococcus granulosus solute carrier family 5 0.0039 0.0046 0.0082
Onchocerca volvulus 0.045 0.0841 0.4552
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0071 0.0108 0.0656
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.018 0.1103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus cathepsin l1 0.0215 0.0387 0.0715
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0119 0.0201 0.1511
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0016 0.0022
Plasmodium falciparum transporter, putative 0.0076 0.0118 0.0909
Brugia malayi mbt repeat family protein 0.0054 0.0075 0.0454
Echinococcus granulosus GPCR family 2 0.0212 0.0382 0.0705
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0012 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0007 0.0029
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0007 0.0009
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0192 0.0342 0.2104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0111 0.0185 0.1474
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0102
Trypanosoma brucei unspecified product 0.0023 0.0014 0.0108
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.0057 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.001 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0058 0.0083 0.0502
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0328 0.0605 0.6798
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Onchocerca volvulus 0.0021 0.001 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.0151 0.1109
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.018 0.0178
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0021 0.001 0.0056
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.0385 0.0383
Echinococcus multilocularis Smad4 0.0026 0.0021 0.0019
Plasmodium vivax serine-repeat antigen (SERA) 0.004 0.0047 0.0342
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Schistosoma mansoni cathepsin F (C01 family) 0.0215 0.0387 0.0715
Onchocerca volvulus 0.0144 0.0249 0.1342
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis sodium and chloride dependent glycine 0.0076 0.0118 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0048 0.0282
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0122 0.0662
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.0385 0.071
Onchocerca volvulus 0.0076 0.0118 0.063
Brugia malayi hypothetical protein 0.0076 0.0118 0.0718
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0075 0.0398
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0122 0.0193
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Entamoeba histolytica cysteine proteinase 1, putative 0.0111 0.0185 0.1405
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0663 0.1254 0.2324
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0014 0.0015
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0031 0.0178
Toxoplasma gondii ABC1 family protein 0.0035 0.0038 0.009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0007 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0176 0.0311 0.2313
Giardia lamblia Hypothetical protein 0.004 0.0047 0.0269
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0212 0.0382 0.038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0048 0.0085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0119 0.0201 0.1511
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.018
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0048 0.0282
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Onchocerca volvulus 0.0076 0.0118 0.063
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0007 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0038 0.0268
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0209 0.0207
Onchocerca volvulus Cathepsin L homolog 0.0215 0.0387 0.209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi cathepsin L precursor 0.004 0.0047 0.0279
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0118 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0048 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Echinococcus granulosus mitogen activated protein kinase 0.0119 0.0201 0.037
Toxoplasma gondii hypothetical protein 0.0076 0.0118 0.0743
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0021 0.001 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0106 0.1041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.001 0.0051
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0119 0.0201 0.1511
Plasmodium vivax vivapain-2 0.0215 0.0387 0.3064
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.3161 0.6092 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0011 0.0017
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0015
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.018 0.1342
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0151 0.0277
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Brugia malayi MAP kinase sur-1 0.0119 0.0201 0.1233
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Loa Loa (eye worm) beta-lactamase 0.0035 0.0038 0.0223
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0119 0.0201 0.1511
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0038 0.0058
Echinococcus multilocularis lamin dm0 0.0058 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1555
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi mbt repeat family protein 0.0054 0.0075 0.0454
Loa Loa (eye worm) hypothetical protein 0.0215 0.0387 0.2384
Onchocerca volvulus 0.0215 0.0387 0.209
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0295 0.0541 0.6062
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0089 0.0537
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0007 0.0009
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0119 0.0201 0.1511
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Loa Loa (eye worm) hydrolase 0.0037 0.0042 0.0247
Brugia malayi tailless protein 0.0019 0.0007 0.0029
Onchocerca volvulus Cathepsin F homolog 0.0215 0.0387 0.209
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.004 0.0047 0.0269
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0075 0.0136
Brugia malayi steroid hormone receptor 0.004 0.0048 0.0282
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Schistosoma mansoni cathepsin C 0.004 0.0047 0.0084
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.009 0.0163
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0192 0.0342 0.2567
Schistosoma mansoni cathepsin S (C01 family) 0.004 0.0047 0.0084
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0144 0.0249 0.1899
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.004 0.0047 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Loa Loa (eye worm) G protein alpha subunit 3 0.0021 0.001 0.0051
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0118 0.0215
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0223
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.0057 0.0348
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0122 0.0662
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0014 0.0022
Echinococcus granulosus geminin 0.0523 0.0982 0.182
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0047 0.0256
Schistosoma mansoni high-affinity choline transporter 0.0355 0.0657 0.1216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0015
Onchocerca volvulus 0.0058 0.0083 0.044
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0089 0.0537
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi MH2 domain containing protein 0.0026 0.0021 0.0119
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0015
Schistosoma mansoni hypothetical protein 0.0459 0.0859 0.1591
Plasmodium falciparum serine repeat antigen 6 0.004 0.0047 0.0342
Schistosoma mansoni sodium/solute symporter 0.0039 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0014 0.0018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Loa Loa (eye worm) cathepsin B 0.004 0.0047 0.0279
Schistosoma mansoni sodium-dependent amino acid transporter 0.0076 0.0118 0.0215
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0201 0.037
Brugia malayi follicle stimulating hormone receptor 0.0278 0.0509 0.3137
Plasmodium vivax glutathione reductase, putative 0.0129 0.022 0.1729
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0007 0.0009
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0089 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0048 0.0282
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.0057 0.042
Echinococcus granulosus cathepsin l1 0.0144 0.0249 0.0459
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0524 0.4131
Trypanosoma brucei cysteine peptidase C (CPC) 0.004 0.0047 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0048 0.0282
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0038 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0048 0.0282
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0021 0.001 0.0051
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0111 0.0109
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.0209 0.0207
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0007 0.0005
Brugia malayi hypothetical protein 0.0114 0.019 0.1164
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0048 0.0282
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Plasmodium falciparum phenylalanine--tRNA ligase 0.0192 0.0342 0.2701
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0048 0.0282
Onchocerca volvulus 0.0076 0.0118 0.063
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0016 0.0047
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.018 0.1436
Loa Loa (eye worm) MH2 domain-containing protein 0.0387 0.0719 0.444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Echinococcus granulosus lamin 0.0058 0.0083 0.0151
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0007 0.0009
Treponema pallidum NADH oxidase 0.0045 0.0057 0.0244
Plasmodium vivax serine-repeat antigen (SERA), putative 0.004 0.0047 0.0342
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0073
Echinococcus multilocularis dna polymerase eta 0.0023 0.0014 0.0012
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0021 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.018 0.1342
Schistosoma mansoni nuclear hormone receptor 0.004 0.0048 0.0085
Plasmodium vivax thioredoxin reductase, putative 0.0129 0.022 0.1729
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0021 0.001 0.0051
Toxoplasma gondii hypothetical protein 0.0076 0.0118 0.0743
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Brugia malayi Muscleblind-like protein 0.0146 0.0253 0.1555
Plasmodium falciparum thioredoxin reductase 0.0045 0.0057 0.042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0328 0.0605 0.0989
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0048 0.0247
Brugia malayi nuclear hormone receptor 0.0019 0.0007 0.0029
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.004 0.0047 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus multilocularis mitogen activated protein kinase 3 0.0119 0.0201 0.0199
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0192 0.0342 0.2104

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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