Detailed information for compound 560931

Basic information

Technical information
  • TDR Targets ID: 560931
  • Name: [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3- yl] 2-hydroxy-2,2-diphenyl-acetate hydrochlor ide
  • MW: 387.9 | Formula: C22H26ClNO3
  • H donors: 1 H acceptors: 2 LogP: 4.66 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(c1ccccc1)(c1ccccc1)O.Cl
  • InChi: 1S/C22H25NO3.ClH/c1-23-18-12-13-19(23)15-20(14-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18-20,25H,12-15H2,1H3;1H/t18-,19+,20?;
  • InChiKey: KBGDDPWSFYFMKX-IIPFOPBBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-hydroxy-2,2-diphenylacetic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester hydrochloride
  • [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenyl-ethanoate hydrochloride
  • 2-hydroxy-2,2-diphenyl-acetic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester hydrochloride
  • [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenylacetate hydrochloride
  • 36173-66-7
  • EINECS 252-897-5
  • exo-8-Methyl-8-azabicyclo(3.2.1)oct-3-yl diphenylglycolate hydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.009 0.0163
Schistosoma mansoni cathepsin C 0.004 0.0047 0.0084
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0192 0.0342 0.2567
Schistosoma mansoni cathepsin S (C01 family) 0.004 0.0047 0.0084
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0144 0.0249 0.1899
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0119 0.0201 0.1511
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Loa Loa (eye worm) hydrolase 0.0037 0.0042 0.0247
Brugia malayi tailless protein 0.0019 0.0007 0.0029
Onchocerca volvulus Cathepsin F homolog 0.0215 0.0387 0.209
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.004 0.0047 0.0269
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0075 0.0136
Brugia malayi steroid hormone receptor 0.004 0.0048 0.0282
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.0057 0.0348
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0122 0.0662
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0014 0.0022
Echinococcus granulosus geminin 0.0523 0.0982 0.182
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0047 0.0256
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.004 0.0047 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Loa Loa (eye worm) G protein alpha subunit 3 0.0021 0.001 0.0051
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0118 0.0215
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0223
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0011 0.0017
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0015
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.018 0.1342
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0151 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Echinococcus granulosus mitogen activated protein kinase 0.0119 0.0201 0.037
Toxoplasma gondii hypothetical protein 0.0076 0.0118 0.0743
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0021 0.001 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0106 0.1041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.001 0.0051
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0119 0.0201 0.1511
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.3161 0.6092 1
Plasmodium vivax vivapain-2 0.0215 0.0387 0.3064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1555
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi mbt repeat family protein 0.0054 0.0075 0.0454
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Loa Loa (eye worm) hypothetical protein 0.0215 0.0387 0.2384
Onchocerca volvulus 0.0215 0.0387 0.209
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0295 0.0541 0.6062
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0089 0.0537
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0007 0.0009
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Brugia malayi MAP kinase sur-1 0.0119 0.0201 0.1233
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Loa Loa (eye worm) beta-lactamase 0.0035 0.0038 0.0223
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0119 0.0201 0.1511
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0038 0.0058
Echinococcus multilocularis lamin dm0 0.0058 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0016 0.0047
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.018 0.1436
Loa Loa (eye worm) MH2 domain-containing protein 0.0387 0.0719 0.444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Echinococcus granulosus lamin 0.0058 0.0083 0.0151
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0007 0.0009
Treponema pallidum NADH oxidase 0.0045 0.0057 0.0244
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Plasmodium vivax serine-repeat antigen (SERA), putative 0.004 0.0047 0.0342
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0073
Echinococcus multilocularis dna polymerase eta 0.0023 0.0014 0.0012
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0038 0.0036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.0209 0.0207
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0007 0.0005
Brugia malayi hypothetical protein 0.0114 0.019 0.1164
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0048 0.0282
Plasmodium falciparum phenylalanine--tRNA ligase 0.0192 0.0342 0.2701
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0048 0.0282
Onchocerca volvulus 0.0076 0.0118 0.063
Brugia malayi Muscleblind-like protein 0.0146 0.0253 0.1555
Plasmodium falciparum thioredoxin reductase 0.0045 0.0057 0.042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0328 0.0605 0.0989
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0048 0.0247
Brugia malayi nuclear hormone receptor 0.0019 0.0007 0.0029
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.004 0.0047 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus multilocularis mitogen activated protein kinase 3 0.0119 0.0201 0.0199
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0192 0.0342 0.2104
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0021 0.0036
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.018 0.1342
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Schistosoma mansoni nuclear hormone receptor 0.004 0.0048 0.0085
Plasmodium vivax thioredoxin reductase, putative 0.0129 0.022 0.1729
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0021 0.001 0.0051
Toxoplasma gondii hypothetical protein 0.0076 0.0118 0.0743
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Schistosoma mansoni sodium/solute symporter 0.0039 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0014 0.0018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Schistosoma mansoni sodium-dependent amino acid transporter 0.0076 0.0118 0.0215
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Loa Loa (eye worm) cathepsin B 0.004 0.0047 0.0279
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Schistosoma mansoni high-affinity choline transporter 0.0355 0.0657 0.1216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.001 0.0015
Onchocerca volvulus 0.0058 0.0083 0.044
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0089 0.0537
Brugia malayi MH2 domain containing protein 0.0026 0.0021 0.0119
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0015
Schistosoma mansoni hypothetical protein 0.0459 0.0859 0.1591
Plasmodium falciparum serine repeat antigen 6 0.004 0.0047 0.0342
Trypanosoma brucei cysteine peptidase C (CPC) 0.004 0.0047 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0048 0.0282
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0038 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0048 0.0282
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0021 0.001 0.0051
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0111 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0201 0.037
Brugia malayi follicle stimulating hormone receptor 0.0278 0.0509 0.3137
Plasmodium vivax glutathione reductase, putative 0.0129 0.022 0.1729
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0007 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0048 0.0282
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0089 0.0087
Echinococcus granulosus cathepsin l1 0.0144 0.0249 0.0459
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.0057 0.042
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0524 0.4131
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus multilocularis abhydrolase domain containing protein 0.0037 0.0042 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Schistosoma mansoni sodium/chloride dependent transporter 0.0078 0.0121 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Loa Loa (eye worm) solute carrier family 6 member 4 0.045 0.0841 0.5193
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0025 0.0042
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0014 0.0015
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0007 0.0009
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0151 0.1109
Brugia malayi hypothetical protein 0.0021 0.0011 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0038 0.0055
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0016 0.0019
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0007 0.0029
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0119 0.0201 0.1511
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0016 0.0022
Plasmodium falciparum transporter, putative 0.0076 0.0118 0.0909
Brugia malayi mbt repeat family protein 0.0054 0.0075 0.0454
Echinococcus granulosus GPCR family 2 0.0212 0.0382 0.0705
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0012 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0007 0.0029
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0192 0.0342 0.2104
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0007 0.0009
Schistosoma mansoni cathepsin B (C01 family) 0.004 0.0047 0.0084
Echinococcus granulosus solute carrier family 5 0.0039 0.0046 0.0082
Onchocerca volvulus 0.045 0.0841 0.4552
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.018 0.1103
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0071 0.0108 0.0656
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus cathepsin l1 0.0215 0.0387 0.0715
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0048 0.0085
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Brugia malayi nuclear receptor RXR 0.0021 0.0011 0.0056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0007 0.0005
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.003 0.0029 0.0231
Brugia malayi cathepsin Z-like cysteine proteinase 0.004 0.0047 0.0279
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0128
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0192 0.0342 0.0631
Onchocerca volvulus 0.0068 0.0102 0.0541
Leishmania major hypothetical protein, conserved 0.0035 0.0038 0.0195
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0004 0.0003
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0048 0.0282
Plasmodium falciparum phenylalanine--tRNA ligase 0.0192 0.0342 0.2701
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0048 0.0085
Echinococcus granulosus cathepsin L cysteine proteinase 0.0215 0.0387 0.0715
Schistosoma mansoni cellular tumor antigen P53 0.0146 0.0253 0.0465
Echinococcus multilocularis serotonin transporter 0.045 0.0841 0.0839
Brugia malayi cathepsin F-like cysteine proteinase 0.0071 0.0108 0.0656
Giardia lamblia Hypothetical protein 0.004 0.0047 0.0269
Onchocerca volvulus 0.0035 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0075 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Plasmodium falciparum serine repeat antigen 7 0.004 0.0047 0.0342
Brugia malayi ecdysone receptor 0.0019 0.0007 0.0029
Onchocerca volvulus 0.0021 0.001 0.0045
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0328 0.0605 0.0989
Schistosoma mansoni sodium/chloride dependent transporter 0.0076 0.0118 0.0215
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0212 0.0382 0.038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0048 0.0085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0119 0.0201 0.1511
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Entamoeba histolytica cysteine proteinase 1, putative 0.0111 0.0185 0.1405
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0663 0.1254 0.2324
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0014 0.0015
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Toxoplasma gondii ABC1 family protein 0.0035 0.0038 0.009
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0031 0.0178
Toxoplasma gondii LsmAD domain-containing protein 0.0176 0.0311 0.2313
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0007 0.0009
Giardia lamblia Hypothetical protein 0.004 0.0047 0.0269
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0209 0.0207
Onchocerca volvulus Cathepsin L homolog 0.0215 0.0387 0.209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi cathepsin L precursor 0.004 0.0047 0.0279
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0118 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0048 0.0085
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.018
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0048 0.0282
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Onchocerca volvulus 0.0076 0.0118 0.063
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0007 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0038 0.0268
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Onchocerca volvulus 0.0021 0.001 0.0045
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.0151 0.1109
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.018 0.0178
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0021 0.001 0.0056
Echinococcus multilocularis Smad4 0.0026 0.0021 0.0019
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.0385 0.0383
Plasmodium vivax serine-repeat antigen (SERA) 0.004 0.0047 0.0342
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Schistosoma mansoni cathepsin F (C01 family) 0.0215 0.0387 0.0715
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0111 0.0185 0.1474
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0102
Trypanosoma brucei unspecified product 0.0023 0.0014 0.0108
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.0057 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0215 0.0387 0.2098
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.001 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0058 0.0083 0.0502
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0328 0.0605 0.6798
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.0385 0.071
Onchocerca volvulus 0.0076 0.0118 0.063
Brugia malayi hypothetical protein 0.0076 0.0118 0.0718
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0075 0.0398
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0122 0.0193
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Onchocerca volvulus 0.0144 0.0249 0.1342
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0048 0.0282
Echinococcus multilocularis sodium and chloride dependent glycine 0.0076 0.0118 0.0116
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0122 0.0662
Schistosoma mansoni Smad4 0.0026 0.0021 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Brugia malayi beta-lactamase 0.0035 0.0038 0.0223
Echinococcus granulosus Smad4 0.0026 0.0021 0.0036
Brugia malayi 6-phosphofructokinase 0.0108 0.018 0.1103
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0482 0.0903 0.1672
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0272
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0048 0.0046
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.009 0.0163
Brugia malayi Smad1 0.0026 0.0021 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Brugia malayi CXXC zinc finger family protein 0.0068 0.0102 0.0617
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0067
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0012 0.0018
Plasmodium vivax unspecified product 0.0111 0.0185 0.1445
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0083 0.0502
Echinococcus multilocularis geminin 0.0523 0.0982 0.098
Echinococcus multilocularis microtubule associated protein 2 0.2798 0.5388 0.5387
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0038 0.0058
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.0201 0.0199
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.004 0.0047 0.0269
Plasmodium vivax amine transporter, putative 0.0076 0.0118 0.0909
Loa Loa (eye worm) fibroinase 0.0215 0.0387 0.2384
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Brugia malayi nuclear receptor NHR-88 0.0019 0.0007 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0048 0.0282
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0007 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0058
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0111 0.0185 0.1381
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Brugia malayi nuclear receptor NHR-88 0.004 0.0048 0.0282
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0663 0.1254 1
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.001 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.0201 0.037
Schistosoma mansoni cpg binding protein 0.0068 0.0102 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Mycobacterium leprae Probable lipase LipE 0.0035 0.0038 0.0253
Trypanosoma cruzi cysteine protease, putative 0.0111 0.0185 0.1381
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0119 0.0201 0.1511
Brugia malayi 6-phosphofructokinase 0.0108 0.018 0.1103
Brugia malayi Cathepsin L-like precursor 0.0144 0.0249 0.1531
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0122 0.0223
Brugia malayi glutathione reductase 0.0129 0.022 0.1352
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Loa Loa (eye worm) serotonin transporter b 0.045 0.0841 0.5193
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0046 0.0082
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0118 0.0909
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0295 0.0541 0.0884
Echinococcus multilocularis musashi 0.0058 0.0083 0.0081
Brugia malayi cathepsin Z-like cysteine proteinase 0.004 0.0047 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Schistosoma mansoni hypothetical protein 0.0102 0.0167 0.0306
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.004 0.0047 0.0342
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0663 0.1254 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0215 0.0387 0.0385
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Onchocerca volvulus 0.0035 0.0038 0.0195
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Echinococcus multilocularis mitogen activated protein kinase 0.0119 0.0201 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0241 0.2595
Echinococcus multilocularis cathepsin b 0.004 0.0047 0.0045
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.001 0.0051
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.0057 0.0244
Onchocerca volvulus 0.0019 0.0007 0.0026
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0663 0.1254 1
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Loa Loa (eye worm) norepinephrine transporter 0.045 0.0841 0.5193
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0038 0.0058
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.004 0.0047 0.0256
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0482 0.0903 0.5573
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.0057 0.0089
Brugia malayi latrophilin 2 splice variant baaae 0.0459 0.0859 0.5303
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0048 0.0085
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0111 0.0202
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.004 0.0047 0.0342
Schistosoma mansoni cathepsin s 0.0071 0.0108 0.0197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Brugia malayi intermediate filament protein 0.0058 0.0083 0.0502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0048 0.0085
Echinococcus multilocularis cathepsin L cysteine protease 0.0215 0.0387 0.0385
Mycobacterium ulcerans hypothetical protein 0.0024 0.0016 0.0019
Brugia malayi GH02984p 0.0355 0.0657 0.4052
Loa Loa (eye worm) histone methyltransferase 0.0025 0.002 0.0109
Loa Loa (eye worm) papain family cysteine protease containing protein 0.004 0.0047 0.0279
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis cpg binding protein 0.0072 0.0109 0.0107
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0016 0.0019
Onchocerca volvulus 0.0319 0.0587 0.3175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0007 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Echinococcus granulosus dna polymerase eta 0.0023 0.0014 0.0022
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0027 0.018
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Schistosoma mansoni survival motor neuron protein 0.0102 0.0167 0.0306
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0048 0.0247
Echinococcus granulosus cysteine protease 0.0111 0.0185 0.034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0482 0.0903 0.0901
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0185 0.1133
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0048 0.0046
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Plasmodium falciparum serine repeat antigen 2 0.004 0.0047 0.0342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0021 0.0019
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0129 0.022 0.0358
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0185 0.1133
Brugia malayi cathepsin B-like cysteine proteinase 0.004 0.0047 0.0279
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0118 0.0215
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.001 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0968 0.1845 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0021 0.001 0.0056
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0048 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi cathepsin F-like cysteine proteinase 0.004 0.0047 0.0279
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0106 0.017
Schistosoma mansoni nuclear receptor 0.0019 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0076 0.0118 0.0215
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0524 0.4052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0007 0.0029
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.004 0.0047 0.0342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0249 0.1351
Mycobacterium tuberculosis Probable reductase 0.0295 0.0541 0.0884
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0743
Brugia malayi hypothetical protein 0.0176 0.0311 0.191
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0021 0.001 0.0056
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0015
Onchocerca volvulus 0.0102 0.0167 0.0894
Brugia malayi conserved hypotetical protein 0.0019 0.0007 0.0029
Schistosoma mansoni hypothetical protein 0.0079 0.0123 0.0225
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0014 0.0108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0057 0.0348
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Giardia lamblia Kinase, CMGC MAPK 0.0119 0.0201 0.1511
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.0144 0.0249 0.1923
Giardia lamblia Cathepsin L-like protease 0.004 0.0047 0.0269
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1555
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0215 0.0387 0.2384
Echinococcus multilocularis smad 0.0026 0.0021 0.0019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0117 0.0197 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0048 0.0282
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0083 0.0502
Echinococcus multilocularis cathepsin L cysteine protease 0.0215 0.0387 0.0385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0047 0.0256
Echinococcus multilocularis thioredoxin glutathione reductase 0.013 0.0221 0.0219
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0295 0.0541 0.0884
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0075 0.0136
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0048 0.0046
Loa Loa (eye worm) phosphofructokinase 0.0108 0.018 0.1103
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 0.6795
Plasmodium vivax vivapain-2 0.0215 0.0387 0.3064
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Plasmodium falciparum serine repeat antigen 8 0.004 0.0047 0.0342
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.004 0.0047 0.0342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0007 0.0029
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.0151 0.0149
Loa Loa (eye worm) Smad1 0.0026 0.0021 0.0119
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0046 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0209 0.0384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Echinococcus multilocularis expressed protein 0.0021 0.001 0.0008
Onchocerca volvulus Cathepsin L homolog 0.004 0.0047 0.0245
Loa Loa (eye worm) hypothetical protein 0.0212 0.0382 0.2349
Brugia malayi Cathepsin L-like precursor 0.0144 0.0249 0.1531
Plasmodium vivax vivapain-1 0.0111 0.0185 0.1445
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0253 0.0251
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.0057 0.0348
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0007 0.0005
Loa Loa (eye worm) thioredoxin reductase 0.0129 0.022 0.1352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0185 0.1003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0119 0.0201 0.142
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0007 0.0029
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0038 0.0067
Plasmodium falciparum serine repeat antigen 5 0.004 0.0047 0.0342
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0119 0.0201 0.1233
Loa Loa (eye worm) latrophilin receptor protein 2 0.0212 0.0382 0.2349
Echinococcus multilocularis tumor protein p63 0.0997 0.19 0.1898
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0048 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0046 0.0044
Schistosoma mansoni thyroid hormone receptor 0.004 0.0048 0.0085
Echinococcus granulosus tar DNA binding protein 0.0061 0.0089 0.0161
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.009 0.0163
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Echinococcus multilocularis cathepsin L 0.004 0.0047 0.0045
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.002 0.0033
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0102
Brugia malayi nuclear receptor RXR 0.0019 0.0007 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0048 0.0046
Brugia malayi hypothetical protein 0.0498 0.0934 0.5768
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0034 0.0197
Onchocerca volvulus 0.0968 0.1845 1
Brugia malayi MH1 domain containing protein 0.0026 0.0021 0.0119
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0122 0.012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Giardia lamblia Cathepsin L-like protease 0.004 0.0047 0.0269
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Onchocerca volvulus Cathepsin L homolog 0.0215 0.0387 0.209
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0016 0.0019
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0663 0.1254 0.1252
Loa Loa (eye worm) hypothetical protein 0.0057 0.0081 0.049
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.0057 0.042
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.018 0.0331
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0021 0.001 0.0051
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0031 0.0178
Mycobacterium tuberculosis Probable oxidoreductase 0.0328 0.0605 0.0989
Onchocerca volvulus 0.0021 0.001 0.0045
Toxoplasma gondii cathepsin CPC1 0.004 0.0047 0.0165
Brugia malayi hypothetical protein 0.0073 0.0111 0.0675
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.0057 0.0452
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0021 0.0036
Trypanosoma brucei protein kinase, putative 0.0119 0.0201 0.1603
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Schistosoma mansoni microtubule-associated protein tau 0.2798 0.5388 1
Brugia malayi nuclear hormone receptor 0.004 0.0048 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.0151 0.081
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0212 0.0382 0.2349
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0185 0.1405
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0014 0.0018
Plasmodium vivax serine-repeat antigen (SERA) 0.004 0.0047 0.0342
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.0151 0.0277
Loa Loa (eye worm) hypothetical protein 0.0054 0.0075 0.0454
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0223
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0046 0.0044
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0015
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0076 0.0118 0.0187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0482 0.0903 0.1672
Plasmodium falciparum thioredoxin reductase 0.0129 0.022 0.1729
Trypanosoma cruzi trypanothione reductase, putative 0.0129 0.022 0.1666
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.002 0.0018
Brugia malayi MH2 domain containing protein 0.0387 0.0719 0.444
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Loa Loa (eye worm) DR-78 0.0019 0.0007 0.0029
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0014 0.0029
Echinococcus granulosus serotonin transporter 0.045 0.0841 0.1558
Onchocerca volvulus 0.004 0.0047 0.0245
Loa Loa (eye worm) ctsf protein 0.0215 0.0387 0.2384
Schistosoma mansoni DNA polymerase eta 0.0023 0.0014 0.0022
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.004 0.0047 0.0342
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0079 0.0123 0.0121
Schistosoma mansoni hypothetical protein 0.0523 0.0982 0.182
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.001 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0048 0.0085
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0007 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0118 0.0215
Onchocerca volvulus 0.004 0.0048 0.0247
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0055
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0016 0.0019
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0012 0.0018
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.004 0.0047 0.0342
Schistosoma mansoni hydrolase 0.0037 0.0042 0.0074
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Loa Loa (eye worm) hypothetical protein 0.0146 0.0253 0.1551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0241 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0295 0.0541 0.0884
Echinococcus granulosus sodium and chloride dependent glycine 0.0076 0.0118 0.0215
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.018 0.1367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0048 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0048 0.0282
Toxoplasma gondii cathepsin CPC2 0.004 0.0047 0.0165
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Echinococcus multilocularis cathepsin L 0.0111 0.0185 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0048 0.0282
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0111 0.0185 0.034
Schistosoma mansoni inositol monophosphatase 0.0078 0.0122 0.0223
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.004 0.0047 0.0342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Mycobacterium ulcerans hypothetical protein 0.0035 0.0038 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0206
Echinococcus granulosus FTZ F1 alpha 0.004 0.0048 0.0085
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0209 0.0384
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0048 0.0085
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0663 0.1254 0.2324
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0192 0.0342 0.1853
Loa Loa (eye worm) hypothetical protein 0.0319 0.0587 0.3621
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0048 0.0282
Echinococcus granulosus expressed protein 0.0021 0.001 0.0015
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0192 0.0342 0.1853
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.004 0.0047 0.0342
Echinococcus granulosus smad 0.0026 0.0021 0.0036
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0027 0.0106
Brugia malayi fibroinase precursor 0.004 0.0047 0.0279
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.018 0.1103
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0151 0.082
Schistosoma mansoni thyroid hormone receptor 0.004 0.0048 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.0201 0.1511
Onchocerca volvulus 0.0215 0.0387 0.209
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0079 0.0123 0.0225
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.0201 0.142
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Mycobacterium tuberculosis Probable dehydrogenase 0.0295 0.0541 0.0884
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0108 0.076
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.004 0.0047 0.0269
Brugia malayi hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.001 0.0015
Echinococcus granulosus high affinity choline transporter 1 0.0355 0.0657 0.1216
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Toxoplasma gondii thioredoxin reductase 0.0129 0.022 0.1577
Toxoplasma gondii cathepsin CPL 0.0215 0.0387 0.2936
Trypanosoma cruzi major cysteine proteinase, putative 0.004 0.0047 0.0269
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0663 0.1254 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0119 0.0201 0.1603
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0452
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.0151 0.0924
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0048 0.0046
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.004 0.0047 0.0084
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0019 0.0106
Onchocerca volvulus 0.0215 0.0387 0.209
Mycobacterium ulcerans lipase LipD 0.0035 0.0038 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0048 0.0282
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.0057 0.0086
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.0057 0.042
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0048 0.0085
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.004 0.0047 0.0269
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0021 0.001 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Leishmania major hypothetical protein, conserved 0.0176 0.0311 0.2394
Loa Loa (eye worm) CXXC zinc finger family protein 0.0068 0.0102 0.0617
Schistosoma mansoni smad 0.0026 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0206
Onchocerca volvulus 0.0024 0.0016 0.0076
Plasmodium vivax ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.3161 0.6092 1
Brugia malayi RNA binding protein 0.0061 0.0089 0.0537
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.001 0.0051
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Schistosoma mansoni hypothetical protein 0.0073 0.0111 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Schistosoma mansoni inositol monophosphatase 0.0078 0.0122 0.0223
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0151 0.1109
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Brugia malayi hypothetical protein 0.0021 0.0011 0.0056
Plasmodium vivax unspecified product 0.004 0.0047 0.0342
Brugia malayi Cathepsin L-like precursor 0.0071 0.0108 0.0656
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Onchocerca volvulus 0.0215 0.0387 0.209
Loa Loa (eye worm) hypothetical protein 0.0459 0.0859 0.5303
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0482 0.0903 0.5573
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0201 0.037
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.001 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0851 0.1618 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.0057 0.0309
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0048 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0482 0.0903 0.1672
Loa Loa (eye worm) papain family cysteine protease containing protein 0.004 0.0047 0.0279
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0034 0.0197
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Giardia lamblia Cysteine protease 0.004 0.0047 0.0269
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Echinococcus multilocularis cysteine protease 0.0215 0.0387 0.0385
Echinococcus granulosus cathepsin L cysteine protease 0.0111 0.0185 0.034
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Echinococcus granulosus cathepsin b 0.004 0.0047 0.0084
Trypanosoma cruzi cruzipain precursor, putative 0.0215 0.0387 0.3011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0027 0.0146
Loa Loa (eye worm) hypothetical protein 0.0671 0.127 0.7849
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0192 0.0342 0.0631
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0038 0.0223
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.0209 0.0384
Plasmodium falciparum serine repeat antigen 9 0.004 0.0047 0.0342
Plasmodium falciparum serine repeat antigen 3 0.004 0.0047 0.0342
Plasmodium falciparum cysteine proteinase falcipain 3 0.0215 0.0387 0.3064
Giardia lamblia Kinase, PLK 0.0094 0.0151 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0215 0.0387 0.2384
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.004 0.0047 0.0084
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0014 0.0012
Trypanosoma brucei PAB1-binding protein , putative 0.0176 0.0311 0.2477
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni zinc finger protein 0.0019 0.0007 0.0009
Echinococcus granulosus dna polymerase kappa 0.0023 0.0014 0.0022
Brugia malayi hypothetical protein 0.0019 0.0007 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.004 0.0047 0.0084
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.001 0.0015
Brugia malayi hydrolase, alpha/beta fold family protein 0.0037 0.0042 0.0247
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0038 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.004 0.0047 0.0256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Leishmania major hypothetical protein, conserved 0.0037 0.0042 0.0227
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0215 0.0387 0.3064
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0075 0.0073
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0122 0.0662
Schistosoma mansoni hypothetical protein 0.0523 0.0982 0.182
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.0057 0.0309
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.0151 0.0924
Brugia malayi Thioredoxin reductase 0.0129 0.022 0.1352
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0663 0.1254 0.7746
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0048 0.0085
Onchocerca volvulus 0.0039 0.0046 0.0238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0027 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Leishmania major trypanothione reductase 0.0129 0.022 0.1666
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0014 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Onchocerca volvulus 0.0058 0.0083 0.044
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.0151 0.1134
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.001 0.0015
Echinococcus granulosus mitogen activated protein kinase 3 0.0119 0.0201 0.037
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0038 0.0058
Onchocerca volvulus 0.0123 0.0209 0.1123
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Schistosoma mansoni inositol transporter 0.0039 0.0046 0.0082
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0012 0.001
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0021 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0014 0.0012
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.001 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Entamoeba histolytica hypothetical protein 0.004 0.0047 0.0297
Brugia malayi hypothetical protein 0.0021 0.001 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Brugia malayi MH2 domain containing protein 0.0026 0.0021 0.0119
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0057 0.0452
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0311 0.2394
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0524 0.4131
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.018 0.0289
Echinococcus granulosus sodium and chloride dependent glycine 0.0076 0.0118 0.0215
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.0201 0.0326
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0038 0.0055
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0075 0.0136
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0011 0.0056
Plasmodium falciparum serine repeat antigen 1 0.004 0.0047 0.0342
Loa Loa (eye worm) glutathione reductase 0.0129 0.022 0.1352
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0048 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0215 0.0387 0.3064
Schistosoma mansoni coup transcription factor 0.004 0.0048 0.0085
Onchocerca volvulus 0.0215 0.0387 0.209
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.001 0.0015
Toxoplasma gondii preprocathepsin c precursor, putative 0.004 0.0047 0.0165
Loa Loa (eye worm) MBCTL1 0.0062 0.009 0.0544
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.009 0.0544
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0007 0.0009
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0046 0.0044
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0021 0.0119
Loa Loa (eye worm) inositol-1 0.0078 0.0122 0.0744
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0038 0.0301
Echinococcus multilocularis survival motor neuron protein 1 0.0498 0.0934 0.0932
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0025 0.0023
Echinococcus multilocularis GPCR, family 2 0.0212 0.0382 0.038
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0471 0.0882 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0076 0.0118 0.0718
Brugia malayi Pre-SET motif family protein 0.0123 0.0209 0.1281
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0122 0.0776
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Toxoplasma gondii cathepsin B 0.004 0.0047 0.0165
Giardia lamblia Dipeptidyl-peptidase I precursor 0.004 0.0047 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0111 0.0185 0.1474
Plasmodium vivax vivapain-3 0.0111 0.0185 0.1445
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0007 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0195
Brugia malayi Cathepsin L-like cysteine proteinase 0.0144 0.0249 0.1531
Echinococcus multilocularis sodium and chloride dependent glycine 0.0076 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0192 0.0342 0.2701
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.001 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.004 0.0047 0.0256
Mycobacterium ulcerans beta-lactamase 0.0035 0.0038 0.0055
Loa Loa (eye worm) hypothetical protein 0.0663 0.1254 0.7746
Brugia malayi ecdysteroid receptor 0.004 0.0048 0.0282
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.001 0.0015
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi Sodium:neurotransmitter symporter family protein 0.045 0.0841 0.5193
Brugia malayi MH1 domain containing protein 0.0026 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0128
Brugia malayi TAR-binding protein 0.0061 0.0089 0.0537
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0021 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Plasmodium falciparum glutathione reductase 0.0129 0.022 0.1729
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Echinococcus granulosus abhydrolase domain containing protein 0.0037 0.0042 0.0074
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0029
Onchocerca volvulus 0.0215 0.0387 0.209
Echinococcus granulosus cathepsin l cysteine peptidase 0.0215 0.0387 0.0715
Schistosoma mansoni sodium/chloride dependent transporter 0.045 0.0841 0.1558
Toxoplasma gondii histone lysine methyltransferase SET1 0.0133 0.0228 0.1638
Loa Loa (eye worm) hypothetical protein 0.0076 0.0118 0.0718
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0089 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0061 0.033
Loa Loa (eye worm) hypothetical protein 0.0144 0.0249 0.1531
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.018 0.0331
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0671 0.127 0.7849
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0048 0.0046
Echinococcus granulosus tumor protein p63 0.0997 0.19 0.3524
Echinococcus granulosus cathepsin L 0.0111 0.0185 0.034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0671 0.127 0.7849
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.3161 0.6092 1
Echinococcus multilocularis cysteine protease 0.0215 0.0387 0.0385
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.009 0.0088
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Echinococcus multilocularis cathepsin b 0.004 0.0047 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0048 0.0282
Onchocerca volvulus 0.0035 0.0038 0.0195
Schistosoma mansoni inositol transporter 0.0039 0.0046 0.0082
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0192 0.0342 0.034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.0057 0.042
Brugia malayi Inositol-1 0.0078 0.0122 0.0744
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0089 0.0537
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Schistosoma mansoni nuclear receptor 0.0019 0.0007 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0201 0.1091
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0007 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0048 0.0282
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0048 0.0282
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.045 0.0841 0.1558
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0108 0.0656
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0011 0.0017
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.001 0.0008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0215 0.0387 0.0385
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0048 0.0282
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0212 0.0382 0.038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0007 0.0026
Schistosoma mansoni kinase 0.0048 0.0063 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0057 0.0348
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0212 0.0382 0.0705
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0075 0.0136
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0011 0.0017
Entamoeba histolytica cysteine protease, putative 0.0215 0.0387 0.3031
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0149 0.0258 0.0475
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0122 0.09
Schistosoma mansoni cathepsin F (C01 family) 0.0215 0.0387 0.0715
Trypanosoma cruzi cysteine peptidase, putative 0.0111 0.0185 0.1381
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0192 0.0342 0.0631
Plasmodium falciparum amino acid transporter, putative 0.0076 0.0118 0.0909
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.004 0.0047 0.0084
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0027 0.0037
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0007 0.0029
Leishmania major cysteine peptidase A (CPA) 0.0215 0.0387 0.3011
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.0057 0.034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0012 0.001
Echinococcus granulosus survival motor neuron protein 1 0.0498 0.0934 0.173
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0278 0.0509 0.3137
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Brugia malayi cathepsin L-like cysteine proteinase 0.004 0.0047 0.0279
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0038 0.0253
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0048 0.0046
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0076 0.0118 0.0116
Brugia malayi Latrophilin receptor protein 2 0.0212 0.0382 0.2349
Schistosoma mansoni intermediate filament proteins 0.0058 0.0083 0.0151
Plasmodium falciparum glutathione reductase 0.0045 0.0057 0.042
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0192 0.0342 0.2701
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.004 0.0047 0.0342
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0057 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0047 0.0279
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.018 0.125
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0046 0.0272
Echinococcus granulosus intermediate filament protein 0.0058 0.0083 0.0151
Schistosoma mansoni hypothetical protein 0.033 0.0609 0.1128
Treponema pallidum sodium- and chloride- dependent transporter 0.045 0.0841 0.6636
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0048 0.0046
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Echinococcus granulosus cathepsin L 0.004 0.0047 0.0084
Echinococcus granulosus muscleblind protein 0.0146 0.0253 0.0466
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0048 0.0085
Trypanosoma cruzi cysteine proteinase, putative 0.0111 0.0185 0.1381
Trypanosoma cruzi major cysteine proteinase, putative 0.004 0.0047 0.0269
Brugia malayi cathepsin L-like precursor 0.0144 0.0249 0.1531
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0047 0.0256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0295 0.0541 0.0884
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0057 0.0348
Giardia lamblia Cathepsin L precursor 0.004 0.0047 0.0269
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.0057 0.0086
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0122 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0011 0.0009
Entamoeba histolytica papain family cysteine protease domain containing protein 0.004 0.0047 0.0297
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0038 0.0223
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0046 0.0082
Schistosoma mansoni cpg binding protein 0.0072 0.0109 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0524 0.284
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Onchocerca volvulus 0.0215 0.0387 0.209
Entamoeba histolytica cysteine protease, putative 0.004 0.0047 0.0297
Brugia malayi nuclear receptor NHR-67 0.0019 0.0007 0.0029
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0076 0.0118 0.0116
Loa Loa (eye worm) RNA binding protein 0.0061 0.0089 0.0537
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.0209 0.1484
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.004 0.0047 0.0084
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.0057 0.0452
Entamoeba histolytica papain family cysteine protease domain containing protein 0.004 0.0047 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.0057 0.0086
Brugia malayi Calcitonin receptor-like protein seb-1 0.0671 0.127 0.7849
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Loa Loa (eye worm) hypothetical protein 0.0123 0.0209 0.1281
Plasmodium vivax serine-repeat antigen (SERA), putative 0.004 0.0047 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0048 0.0282
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0282
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0076 0.0118 0.0116
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.018 0.0331
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.018 0.0292
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.001 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0048 0.0282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0215 0.0387 0.2098
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0663 0.1254 1
Trichomonas vaginalis esterase, putative 0.0035 0.0038 0.0206
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0007 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0215 0.0387 0.3087
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.018 0.0977
Loa Loa (eye worm) transcription factor SMAD2 0.0387 0.0719 0.444
Trypanosoma cruzi cysteine peptidase, putative 0.0215 0.0387 0.3011
Trypanosoma cruzi cysteine proteinase, putative 0.0111 0.0185 0.1381
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0223
Entamoeba histolytica cysteine protease, putative 0.0111 0.0185 0.1405
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.004 0.0047 0.0342
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0663 0.1254 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0000000000038713 0.000000000020979
Loa Loa (eye worm) hypothetical protein 0.045 0.0841 0.5193
Brugia malayi hypothetical protein 0.0319 0.0587 0.3621
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0048 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Plasmodium falciparum epoxide hydrolase 1 0.0037 0.0042 0.03
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0111 0.0202
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0014 0.0108
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0311 0.2451
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0048 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0048 0.0282
Plasmodium falciparum cysteine proteinase falcipain 1 0.0111 0.0185 0.1445
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0201 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Entamoeba histolytica cysteine proteinase 2 0.0111 0.0185 0.1405
Entamoeba histolytica cysteine proteinase, putative 0.0215 0.0387 0.3031
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0524 0.4115
Loa Loa (eye worm) hypothetical protein 0.0176 0.0311 0.191
Brugia malayi Pre-SET motif family protein 0.0851 0.1618 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.009 0.0088
Brugia malayi Papain family cysteine protease containing protein 0.0215 0.0387 0.2384
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0663 0.1254 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0016 0.0047
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0007 0.0005
Onchocerca volvulus 0.0054 0.0075 0.0398
Giardia lamblia Encystation-specific protease 0.004 0.0047 0.0269
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0027 0.018
Schistosoma mansoni hypothetical protein 0.0212 0.0382 0.0705
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.018 0.1896
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0144 0.0249 0.1351
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0056
Echinococcus granulosus lamin dm0 0.0058 0.0083 0.0151
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0016 0.0018
Brugia malayi cahepsin L-like non-peptiedase homolog 0.004 0.0047 0.0279
Schistosoma mansoni smad1 5 8 and 0.0026 0.0021 0.0036
Schistosoma mansoni lamin 0.0058 0.0083 0.0151
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0038 0.0058
Onchocerca volvulus 0.0019 0.0007 0.0026
Plasmodium falciparum serine repeat antigen 4 0.004 0.0047 0.0342
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0482 0.0903 0.0901
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0241 0.0388
Echinococcus multilocularis high affinity choline transporter 1 0.0355 0.0657 0.0655
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0046 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0014 0.0073
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0083 0.0502
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0016 0.0047
Giardia lamblia Cathepsin B precursor 0.004 0.0047 0.0269
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0016 0.0019
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.3161 0.6092 1
Brugia malayi phosphofructokinase 0.0108 0.018 0.1103
Onchocerca volvulus 0.003 0.0029 0.0147
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.001 0.0015
Schistosoma mansoni lamin 0.0058 0.0083 0.0151
Echinococcus granulosus thioredoxin glutathione reductase 0.013 0.0221 0.0407
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0167 0.102
Echinococcus multilocularis lamin 0.0058 0.0083 0.0081
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0014 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0279
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0122 0.0874
Loa Loa (eye worm) cysteine protease 0.0215 0.0387 0.2384
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Echinococcus multilocularis muscleblind protein 0.0146 0.0253 0.0251
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0048 0.0085
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0075 0.0136
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Echinococcus granulosus cpg binding protein 0.0072 0.0109 0.0199
Loa Loa (eye worm) hypothetical protein 0.0498 0.0934 0.5768
Entamoeba histolytica cysteine proteinase, putative 0.0215 0.0387 0.3031
Echinococcus multilocularis solute carrier family 5 0.0039 0.0046 0.0044
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0075 0.0454
Brugia malayi G-protein alpha subunit 0.0021 0.001 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0311 0.2394
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.0057 0.0348
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0118 0.0215
Schistosoma mansoni cathepsin F (C01 family) 0.0144 0.0249 0.0459
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0201 0.0323
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0046 0.0082
Entamoeba histolytica hypothetical protein 0.0073 0.0111 0.081
Loa Loa (eye worm) hypothetical protein 0.0062 0.009 0.0544
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.004 0.0047 0.0342
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0076 0.0118 0.0718
Trypanosoma brucei polo-like protein kinase 0.0094 0.0151 0.1205
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0016 0.0022
Onchocerca volvulus 0.0146 0.0253 0.136
Plasmodium vivax SET domain protein, putative 0.0123 0.0209 0.1637
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.001 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0108 0.076
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.004 0.0047 0.0256
Echinococcus granulosus microtubule associated protein 2 0.2798 0.5388 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0212 0.0382 0.0705
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0048 0.0282
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0014 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0027 0.0146
Leishmania major cathepsin L-like protease 0.0215 0.0387 0.3011
Plasmodium vivax unspecified product 0.0071 0.0108 0.0829
Echinococcus granulosus cathepsin b 0.004 0.0047 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0061 0.033
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0014 0.0108
Schistosoma mansoni cpg binding protein 0.0072 0.0109 0.0199
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.001 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0215 0.0387 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0048 0.0282
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0403 0.0658
Loa Loa (eye worm) hypothetical protein 0.0355 0.0657 0.4052
Brugia malayi Cathepsin L-like precursor 0.0215 0.0387 0.2384
Trypanosoma brucei trypanothione reductase 0.0129 0.022 0.1756
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0185 0.1003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0108 0.0656

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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