Detailed information for compound 572688

Basic information

Technical information
  • TDR Targets ID: 572688
  • Name: quassimarin
  • MW: 522.542 | Formula: C26H34O11
  • H donors: 3 H acceptors: 7 LogP: 0.06 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC[C@H](C(=O)O[C@H]1C(=O)O[C@H]2[C@]34[C@@H]1[C@](C)(OC3)[C@@H](O)[C@@H]([C@@H]4[C@@]1([C@@H](C2)C(=CC(=O)[C@H]1O)C)C)O)OC(=O)C
  • InChi: 1S/C26H34O11/c1-6-14(35-11(3)27)22(32)37-17-19-25(5)21(31)16(29)18-24(4)12(10(2)7-13(28)20(24)30)8-15(36-23(17)33)26(18,19)9-34-25/h7,12,14-21,29-31H,6,8-9H2,1-5H3/t12-,14+,15+,16+,17+,18+,19-,20+,21-,24-,25-,26+/m0/s1
  • InChiKey: QOXAISGIEITGJU-HGXLBWMBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 59938-97-5
  • C08777

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.014 0.0102 0.1739
Echinococcus multilocularis GPCR, family 2 0.0143 0.0105 0.0105
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Mycobacterium leprae Probable lipase LipE 0.0446 0.0419 0.4181
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0288 0.0256 0.435
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0107 0.0068 0.0169
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0012 0.0206
Brugia malayi Pre-SET motif family protein 0.0565 0.0543 0.1353
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0023 0.0391
Schistosoma mansoni transient receptor potential channel 0.0094 0.0055 0.0055
Leishmania major 4-coumarate:coa ligase-like protein 0.0478 0.0453 0.7702
Brugia malayi Protein cec-1. 0.0059 0.0017 0.0043
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.001 0.0025
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0093 0.0053 0.0898
Schistosoma mansoni jumonji domain containing protein 0.0119 0.008 0.008
Brugia malayi Hhat protein 0.0601 0.0581 0.1447
Giardia lamblia Fructose-bisphosphate aldolase 0.2047 0.2082 1
Trichomonas vaginalis Heterochromatin protein, putative 0.0059 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0081 0.004 0.004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0008 0.002
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0017 0.0047
Schistosoma mansoni Smad4 0.0051 0.001 0.001
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0601 0.0581 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0288 0.0256 0.0638
Trypanosoma cruzi hypothetical protein, conserved 0.0446 0.0419 0.7129
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0446 0.0419 0.4181
Echinococcus granulosus apoptotic protease activating factor 1 0.0315 0.0284 0.0284
Echinococcus granulosus lysine specific demethylase 6a 0.0119 0.008 0.008
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.028 0.0247 0.0616
Schistosoma mansoni jumonji domain containing protein 0.0618 0.0598 0.0598
Echinococcus multilocularis transient receptor potential gamma protein 0.0094 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0059 0.0017 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Loa Loa (eye worm) hypothetical protein 0.0357 0.0327 0.0816
Echinococcus multilocularis smad 0.0051 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0415 0.0387 0.0387
Loa Loa (eye worm) beta-lactamase 0.0446 0.0419 0.1045
Echinococcus multilocularis lysine specific demethylase 6a 0.0119 0.008 0.008
Echinococcus granulosus transcription factor Dp 1 0.0114 0.0075 0.0075
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0601 0.0581 0.279
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0446 0.0419 0.1422
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.028 0.0247 0.7501
Loa Loa (eye worm) hypothetical protein 0.0326 0.0295 0.0735
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.014 0.0102 0.1739
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0013 0.0013
Brugia malayi Bromodomain containing protein 0.0248 0.0214 0.0533
Schistosoma mansoni acetyl-CoA synthetase 0.014 0.0102 0.0102
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0701 0.0685 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Schistosoma mansoni alpha-glucosidase 0.0137 0.0099 0.0099
Trichomonas vaginalis set domain proteins, putative 0.4446 0.4572 1
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0138 0.01 0.01
Echinococcus granulosus histone lysine methyltransferase setb 0.0617 0.0597 0.0597
Echinococcus multilocularis snurportin 1 0.0905 0.0896 0.0896
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0608 0.0588 1
Entamoeba histolytica hypothetical protein 0.0069 0.0028 0.0134
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0028 0.0061
Entamoeba histolytica acyl-CoA synthetase, putative 0.0478 0.0453 0.2176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0357 0.0327 0.0816
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Mycobacterium ulcerans beta-lactamase 0.0446 0.0419 0.4181
Echinococcus granulosus caspase 3 0.0222 0.0187 0.0187
Trypanosoma brucei glycerol uptake protein, putative 0.0601 0.0581 0.9874
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0601 0.0581 0.0581
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0072 0.0031 0.0031
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0305 0.0273 0.1311
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 1
Loa Loa (eye worm) hypothetical protein 0.0453 0.0426 0.1063
Leishmania major acetyl-CoA synthetase, putative 0.014 0.0102 0.1739
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0017 0.0083
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.0052 0.0052
Brugia malayi hypothetical protein 0.1184 0.1186 0.2956
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0478 0.0453 0.4522
Trichomonas vaginalis antibiotic synthetase, putative 0.014 0.0102 0.0224
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0013 0.022
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0601 0.0581 0.0581
Brugia malayi CHD4 protein 0.0078 0.0037 0.0092
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0301 0.0269 0.0906
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Plasmodium vivax importin-beta 2, putative 0.0085 0.0045 0.0121
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0197 0.0161 0.0161
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0197 0.0161 0.0161
Echinococcus granulosus jumonji domain containing protein 0.0172 0.0135 0.0135
Schistosoma mansoni cpg binding protein 0.0231 0.0196 0.0196
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Onchocerca volvulus Alhambra homolog 0.0124 0.0085 0.018
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.014 0.0102 0.0332
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0006 0.0006
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0021 0.0021
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0013 0.0013
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0021 0.0021
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0478 0.0453 0.4522
Onchocerca volvulus 0.0446 0.0419 0.0911
Loa Loa (eye worm) hypothetical protein 0.0441 0.0414 0.1032
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.014 0.0102 0.0491
Echinococcus granulosus neuropeptide s receptor 0.1381 0.139 0.139
Echinococcus granulosus phd:f box containing protein 0.0119 0.008 0.008
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0112 0.0073 0.0679
Loa Loa (eye worm) hypothetical protein 0.0169 0.0132 0.0329
Echinococcus granulosus lamin dm0 0.0081 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0617 0.0597 0.0597
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0081 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0081 0.0041 0.0102
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0059 0.0017 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0017 0.0038
Leishmania major hypothetical protein, conserved 0.0047 0.0005 0.0093
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Echinococcus multilocularis lamin dm0 0.0081 0.0041 0.0041
Trypanosoma brucei glycerol uptake protein, putative 0.0601 0.0581 0.9874
Brugia malayi ecdysteroid receptor 0.0059 0.0018 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.0165 0.0361
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0163 0.0126 0.0606
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0083 0.0042 0.0093
Brugia malayi MBOAT family protein 0.0601 0.0581 0.1447
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.3578 0.3671 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0059 0.0018 0.0045
Trypanosoma cruzi metacaspase, putative 0.0135 0.0097 0.1641
Loa Loa (eye worm) hhat protein 0.0601 0.0581 0.1447
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.028 0.0247 0.4202
Loa Loa (eye worm) helicase 0.0059 0.0017 0.0043
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0006 0.0006
Echinococcus granulosus peregrin 0.0135 0.0096 0.0096
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0008 0.002
Echinococcus granulosus FTZ F1 alpha 0.0059 0.0018 0.0018
Echinococcus multilocularis caspase 8 0.0135 0.0097 0.0097
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.0091 0.0227
Echinococcus multilocularis protein dispatched 1 0.0291 0.0259 0.0259
Loa Loa (eye worm) jmjC domain-containing protein 0.0465 0.0439 0.1094
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.0052 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0086 0.0045 0.077
Leishmania major hypothetical protein, conserved 0.0119 0.008 0.1359
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0143 0.0105 0.0105
Echinococcus granulosus dna polymerase eta 0.0092 0.0052 0.0052
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0078 0.0037 0.0037
Plasmodium falciparum diacylglycerol O-acyltransferase 0.3578 0.3671 1
Plasmodium falciparum acyl-CoA synthetase 0.0357 0.0327 0.0892
Echinococcus multilocularis sterol regulatory element binding protein 0.0255 0.0221 0.0221
Brugia malayi serine/threonine-protein kinase plk-2 0.0288 0.0256 0.0638
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0305 0.0273 0.0744
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0112 0.0112
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0183 0.0146 0.142
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.001 0.0027
Brugia malayi Valyl-tRNA synthetase 0.0059 0.0017 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.0059 0.0018 0.0045
Schistosoma mansoni hypothetical protein 0.0246 0.0212 0.0212
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2848 0.2913 1
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0601 0.0581 0.0581
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.014 0.0102 0.0102
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0059 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Onchocerca volvulus 0.4446 0.4572 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0059 0.0018 0.0045
Loa Loa (eye worm) transcription factor SMAD2 0.0754 0.074 0.1843
Echinococcus multilocularis chromobox protein 1 0.0358 0.0328 0.0328
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0072 0.0031 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Trichomonas vaginalis porcupine, putative 0.0601 0.0581 0.127
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0601 0.0581 0.0581
Loa Loa (eye worm) glutaminase 2 0.0276 0.0243 0.0605
Brugia malayi hypothetical protein 0.0464 0.0438 0.1092
Echinococcus granulosus Niemann Pick C1 protein 0.0595 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0013 0.022
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.001 0.0027
Mycobacterium tuberculosis Probable lipase LipD 0.0446 0.0419 0.1422
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0112 0.0112
Entamoeba histolytica hypothetical protein 0.0048 0.0006 0.0028
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0064 0.0023 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0059 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0018 0.0018
Echinococcus multilocularis caspase 0.0357 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0089 0.0049 0.0122
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0214 0.0178 0.0593
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0338 0.0307 0.1037
Brugia malayi Cell death protein 3 precursor 0.045 0.0424 0.1056
Schistosoma mansoni microtubule-associated protein tau 0.9675 1 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.014 0.0102 0.0255
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.008 0.0199
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0119 0.008 0.1359
Plasmodium vivax heterochromatin protein 1, putative 0.0059 0.0017 0.0047
Schistosoma mansoni hypothetical protein 0.0143 0.0105 0.0105
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.3578 0.3671 0.3671
Schistosoma mansoni smad 0.0051 0.001 0.001
Echinococcus granulosus importin subunit beta 1 0.0085 0.0045 0.0045
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0082 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.0446 0.0419 0.0917
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0017 0.0038
Echinococcus multilocularis cpg binding protein 0.025 0.0216 0.0216
Brugia malayi Heterochromatin protein 1 0.0358 0.0328 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Loa Loa (eye worm) hypothetical protein 0.0048 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0478 0.0453 0.1129
Loa Loa (eye worm) hypothetical protein 0.2976 0.3046 0.7593
Plasmodium falciparum metacaspase-like protein 0.0135 0.0097 0.0263
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.014 0.0102 0.0975
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0017 0.0083
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0601 0.0581 0.0581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Schistosoma mansoni bromodomain containing protein 0.0212 0.0176 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.039
Leishmania major acetyl-CoA synthetase, putative 0.014 0.0102 0.1739
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0338 0.0307 0.1037
Brugia malayi hypothetical protein 0.0441 0.0414 0.1032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.0018 0.0045
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0006 0.0007
Toxoplasma gondii histone lysine methyltransferase SET1 0.0468 0.0443 0.1206
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0197 0.0161 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0478 0.0453 0.1129
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.008 0.0199
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Brugia malayi AMP-binding enzyme family protein 0.014 0.0102 0.0255
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0006 0.0006
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0288 0.0255 0.4343
Entamoeba histolytica serine/threonine protein kinase, putative 0.0288 0.0256 0.1229
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.028 0.0247 0.4202
Brugia malayi nuclear hormone receptor 0.0059 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.014 0.0102 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.014 0.0102 0.0332
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0054 0.0013 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Trypanosoma brucei polo-like protein kinase 0.0288 0.0256 0.435
Toxoplasma gondii isocitrate dehydrogenase 0.0064 0.0023 0.0063
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0054 0.0013 0.0062
Brugia malayi SET domain containing protein 0.0084 0.0044 0.011
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.001 0.001
Onchocerca volvulus 0.0478 0.0453 0.0985
Loa Loa (eye worm) hypothetical protein 0.0357 0.0327 0.0816
Schistosoma mansoni kinase 0.0147 0.0109 0.0109
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.014 0.0102 0.0975
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0059 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Echinococcus granulosus transcription factor eb 0.0108 0.0068 0.0068
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0054 0.0013 0.0013
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0078 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0107 0.0068 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0059 0.0017 0.0047
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0059 0.0017 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0446 0.0419 0.1142
Giardia lamblia Kinase, PLK 0.0288 0.0256 0.1229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Schistosoma mansoni hypothetical protein 0.0246 0.0212 0.0212
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0656 0.0637 0.0637
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0059 0.0018 0.0018
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0094 0.0055 0.0136
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0002 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0018 0.0018
Schistosoma mansoni smad1 5 8 and 0.0051 0.001 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0446 0.0419 0.4181
Schistosoma mansoni chromobox protein 0.0358 0.0328 0.0328
Toxoplasma gondii ABC1 family protein 0.0446 0.0419 0.1142
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0357 0.0327 0.0327
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0305 0.0273 0.0744
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0197 0.0161 0.0402
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Brugia malayi isocitrate dehydrogenase 0.0064 0.0023 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0012 0.0027
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0045 0.077
Trypanosoma brucei metacaspase MCA2 0.0135 0.0097 0.1641
Brugia malayi MH1 domain containing protein 0.0051 0.001 0.0025
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.2922
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Mycobacterium ulcerans hypothetical protein 0.0478 0.0453 0.4522
Mycobacterium tuberculosis Conserved protein 0.0446 0.0419 0.1422
Brugia malayi MH2 domain containing protein 0.0754 0.074 0.1843
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0059 0.0018 0.0045
Loa Loa (eye worm) TAR-binding protein 0.0129 0.0091 0.0227
Loa Loa (eye worm) RNA binding protein 0.0129 0.0091 0.0227
Schistosoma mansoni cpg binding protein 0.025 0.0216 0.0216
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0086 0.0045 0.077
Loa Loa (eye worm) AMP-binding enzyme family protein 0.014 0.0102 0.0255
Echinococcus multilocularis protein patched 0.0255 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0092 0.0052 0.0052
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0009 0.0148
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0112 0.0073 0.0199
Toxoplasma gondii aldehyde dehydrogenase 0.0301 0.0269 0.0733
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0059 0.0018 0.0018
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.014 0.0102 0.0975
Schistosoma mansoni hypothetical protein 0.0246 0.0212 0.0212
Echinococcus multilocularis neuropeptide receptor A26 0.1381 0.139 0.139
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.001 0.001
Onchocerca volvulus 0.0315 0.0284 0.0615
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0017 0.0038
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0023 0.0056
Brugia malayi MBOAT family protein 0.0601 0.0581 0.1447
Schistosoma mansoni caspase-3 (C14 family) 0.0357 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.045 0.0424 0.1056
Schistosoma mansoni lozenge 0.0055 0.0014 0.0014
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0197 0.0161 0.2743
Echinococcus granulosus GPCR family 2 0.0143 0.0105 0.0105
Trypanosoma cruzi polo-like protein kinase, putative 0.0288 0.0256 0.435
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0078 0.0037 0.0037
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Loa Loa (eye worm) jmjC domain-containing protein 0.0256 0.0222 0.0553
Brugia malayi Isocitrate dehydrogenase 0.0064 0.0023 0.0057
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0012 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0415 0.0387 0.0387
Schistosoma mansoni intermediate filament proteins 0.0081 0.0041 0.0041
Trypanosoma brucei ISWI complex protein 0.0047 0.0005 0.0093
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0111 0.0072 0.0072
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0617 0.0597 0.0597
Mycobacterium ulcerans hypothetical protein 0.0446 0.0419 0.4181
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0059 0.0018 0.0045
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0059 0.0018 0.0018
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0122 0.0122
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0081 0.004 0.01
Loa Loa (eye worm) PHD-finger family protein 0.0124 0.0085 0.0212
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0054 0.0013 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0446 0.0419 0.0917
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0119 0.008 0.008
Trypanosoma brucei protein kinase, putative 0.0054 0.0012 0.0206
Echinococcus granulosus smad 0.0051 0.001 0.001
Echinococcus granulosus jumonji domain containing 1A 0.0119 0.008 0.008
Trypanosoma cruzi glycerol uptake protein, putative 0.0601 0.0581 0.9874
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0072 0.0031 0.0031
Trichomonas vaginalis glutaminase, putative 0.0276 0.0243 0.0531
Brugia malayi jmjC domain containing protein 0.0119 0.008 0.0199
Brugia malayi Latrophilin receptor protein 2 0.0143 0.0105 0.0262
Trypanosoma cruzi ISWI complex protein 0.0047 0.0005 0.0093
Entamoeba histolytica hypothetical protein, conserved 0.0601 0.0581 0.279
Loa Loa (eye worm) hypothetical protein 0.0464 0.0438 0.1092
Trichomonas vaginalis hypothetical protein 0.0059 0.0017 0.0038
Echinococcus granulosus caspase 2 0.045 0.0424 0.0424
Schistosoma mansoni hypothetical protein 0.1029 0.1024 0.1024
Echinococcus multilocularis isocitrate dehydrogenase 0.0064 0.0023 0.0023
Brugia malayi MBOAT family protein 0.0601 0.0581 0.1447
Brugia malayi PHD-finger family protein 0.0093 0.0054 0.0133
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.028 0.0247 0.0247
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.039
Loa Loa (eye worm) hypothetical protein 0.0357 0.0327 0.0816
Schistosoma mansoni steroid hormone receptor ad4bp 0.0059 0.0018 0.0018
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0006 0.0016
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0119 0.008 0.1359
Schistosoma mansoni hypothetical protein 0.0601 0.0581 0.0581
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0059 0.0018 0.0018
Brugia malayi diacylglycerol acyltransferase 0.3578 0.3671 0.9149
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0025
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.2922
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0021 0.0021
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0478 0.0453 0.4522
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0301 0.0269 0.0269
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0601 0.0581 0.279
Plasmodium vivax acyl-CoA synthetase, putative 0.0357 0.0327 0.0892
Echinococcus granulosus sterol regulatory element binding protein 0.0255 0.0221 0.0221
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0288 0.0255 0.4343
Echinococcus granulosus dnaJ subfamily B 0.3286 0.3368 0.3368
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.0091 0.0227
Echinococcus multilocularis peptidase Clp (S14 family) 0.0214 0.0178 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.0102 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0143 0.0105 0.0105
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0012 0.0027
Echinococcus multilocularis expressed conserved protein 0.0558 0.0536 0.0536
Echinococcus multilocularis Smad4 0.0051 0.001 0.001
Echinococcus granulosus transient receptor potential gamma protein 0.0094 0.0055 0.0055
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.1392
Schistosoma mansoni peptidase Clp (S14 family) 0.0326 0.0295 0.0295
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.014 0.0102 0.0332
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.3578 0.3671 0.3671
Leishmania major 4-coumarate:coa ligase-like protein 0.0478 0.0453 0.7702
Brugia malayi SET domain containing protein 0.0045 0.0003 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0017 0.0038
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0017 0.0017
Onchocerca volvulus 0.0169 0.0132 0.0283
Entamoeba histolytica acyl-CoA synthetase, putative 0.0478 0.0453 0.2176
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0059 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0298 0.0266 0.0266
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0006 0.0006
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0012 0.0206
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0216 0.0181 0.0389
Echinococcus granulosus JmjC domain containing protein 4 0.0119 0.008 0.008
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.001 0.0027
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0064 0.0023 0.0391
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0013 0.0032
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0072 0.0031 0.0523
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0701 0.0685 0.0685
Loa Loa (eye worm) glutaminase 0.0276 0.0243 0.0605
Loa Loa (eye worm) heterochromatin protein 1 0.0358 0.0328 0.0818
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0415 0.0387 0.0387
Onchocerca volvulus 0.0601 0.0581 0.1265
Brugia malayi latrophilin 2 splice variant baaae 0.0309 0.0278 0.0692
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0111 0.0072 0.0157
Schistosoma mansoni hypothetical protein 0.0246 0.0212 0.0212
Echinococcus granulosus L aminoadipate semialdehyde 0.0169 0.0132 0.0132
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Brugia malayi hypothetical protein 0.0315 0.0284 0.0707
Leishmania major 4-coumarate:coa ligase-like protein 0.0478 0.0453 0.7702
Schistosoma mansoni glutaminase 0.0276 0.0243 0.0243
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0031 0.0252
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0017 0.0292
Loa Loa (eye worm) hypothetical protein 0.008 0.0039 0.0098
Onchocerca volvulus 0.0059 0.0017 0.0032
Echinococcus multilocularis caspase 3 0.0222 0.0187 0.0187
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0169 0.0132 0.0329
Schistosoma mansoni zinc finger protein 0.0601 0.0581 0.0581
Echinococcus multilocularis caspase 2 0.045 0.0424 0.0424
Trichomonas vaginalis chromobox protein, putative 0.0358 0.0328 0.0718
Loa Loa (eye worm) oxidoreductase 0.014 0.0102 0.0255
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.039
Plasmodium vivax metacaspase 1, putative 0.0135 0.0097 0.0263
Schistosoma mansoni hypothetical protein 0.0656 0.0637 0.0637
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0012 0.0012
Schistosoma mansoni thyroid hormone receptor 0.02 0.0164 0.0164
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0608 0.0588 1
Trypanosoma brucei DNA polymerase eta, putative 0.0092 0.0052 0.0886
Schistosoma mansoni hypothetical protein 0.0059 0.0017 0.0017
Schistosoma mansoni transient receptor potential channel 0.0062 0.0021 0.0021
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0011 0.0027
Echinococcus granulosus chromobox protein 1 0.0358 0.0328 0.0328
Brugia malayi MBOAT family protein 0.0601 0.0581 0.1447
Plasmodium falciparum heterochromatin protein 1 0.0059 0.0017 0.0047
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0214 0.0178 0.1743
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.1 0.0995 0.3401
Schistosoma mansoni zinc finger protein 0.0077 0.0036 0.0036
Brugia malayi MAP kinase sur-1 0.0054 0.0012 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0446 0.0419 0.1045
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0054 0.0013 0.0013
Echinococcus granulosus fetal alzheimer antigen falz 0.0083 0.0042 0.0042
Plasmodium vivax SET domain protein, putative 0.0565 0.0543 0.1478
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.014 0.0102 0.0975
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0059 0.0018 0.0045
Loa Loa (eye worm) MBOAT family protein 0.0601 0.0581 0.1447
Schistosoma mansoni jumonji/arid domain-containing protein 0.0465 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.0085 0.0045 0.0111
Leishmania major mitochondrial DNA polymerase beta 0.0608 0.0588 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0163 0.0126 0.0606
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Echinococcus multilocularis ubiquitin specific protease 41 0.0054 0.0013 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.085 0.0839 0.0839
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Echinococcus granulosus chromobox protein 2 0.0059 0.0017 0.0017
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0301 0.0269 0.0269
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.6529 0.6734 0.6734
Leishmania major DNA polymerase eta, putative 0.0065 0.0024 0.0403
Trypanosoma cruzi metacaspase 5, putative 0.0135 0.0097 0.1641
Brugia malayi Associated with TFs and helicases family protein 0.0059 0.0017 0.0043
Onchocerca volvulus Serine\/threonine kinase homolog 0.0288 0.0256 0.0554
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.0052 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Mycobacterium tuberculosis Probable lipase LipE 0.0446 0.0419 0.1422
Trypanosoma cruzi metacaspase, putative 0.0135 0.0097 0.1641
Schistosoma mansoni zinc finger protein 0.0047 0.0005 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.085 0.0839 0.0839
Trichomonas vaginalis transmembrane protein nessy, putative 0.0601 0.0581 0.127
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0197 0.0161 0.0402
Loa Loa (eye worm) hypothetical protein 0.0135 0.0097 0.0241
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0143 0.0105 0.0105
Plasmodium falciparum phd finger protein, putative 0.0124 0.0085 0.0232
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2047 0.2082 1
Echinococcus multilocularis Chromobox protein 3 0.0059 0.0017 0.0017
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0601 0.0581 0.0581
Echinococcus granulosus snurportin 1 0.0905 0.0896 0.0896
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0608 0.0588 1
Echinococcus granulosus Chromo domain 0.0059 0.0017 0.0017
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.014 0.0102 0.0975
Onchocerca volvulus 0.0465 0.0439 0.0954
Loa Loa (eye worm) hypothetical protein 0.0601 0.0581 0.1447
Brugia malayi mbt repeat family protein 0.0048 0.0006 0.0015
Echinococcus multilocularis transcription factor Dp 1 0.0114 0.0075 0.0075
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0446 0.0419 0.1045
Echinococcus granulosus Smad4 0.0051 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Schistosoma mansoni jumonji/arid domain-containing protein 0.0465 0.0439 0.0439
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0601 0.0581 0.0581
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0012 0.0206
Echinococcus granulosus tumor protein p63 0.3175 0.3252 0.3252
Loa Loa (eye worm) hypothetical protein 0.014 0.0102 0.0255
Schistosoma mansoni lamin 0.0081 0.0041 0.0041
Trichomonas vaginalis chromobox protein, putative 0.0358 0.0328 0.0718
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0059 0.0018 0.0045
Leishmania major glycerol uptake protein, putative 0.0601 0.0581 0.9874
Brugia malayi AMP-binding enzyme family protein 0.014 0.0102 0.0255
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0008 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Brugia malayi F/Y-rich N-terminus family protein 0.0137 0.0099 0.0247
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0197 0.0161 0.2743
Loa Loa (eye worm) bromodomain containing protein 0.0058 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0129 0.0091 0.0226
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0059 0.0018 0.0045
Echinococcus multilocularis FTZ F1 alpha 0.0059 0.0018 0.0018
Loa Loa (eye worm) isocitrate dehydrogenase 0.0064 0.0023 0.0057
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0008 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Mycobacterium tuberculosis Conserved protein 0.0446 0.0419 0.1422
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0012 0.0206
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.0052 0.0052
Onchocerca volvulus 0.0464 0.0438 0.0952
Loa Loa (eye worm) hypothetical protein 0.0441 0.0414 0.1032
Plasmodium vivax acetyl-CoA synthetase, putative 0.014 0.0102 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.0018 0.0045
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0122 0.0304
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0105 0.0229
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0601 0.0581 0.0581
Schistosoma mansoni SET domain protein 0.0045 0.0003 0.0003
Brugia malayi glucose-6-phosphate dehydrogenase 0.028 0.0247 0.0616
Echinococcus multilocularis jumonji domain containing protein 0.0172 0.0135 0.0135
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0135 0.0097 0.0263
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0565 0.0543 0.0543
Onchocerca volvulus 0.0446 0.0419 0.0911
Loa Loa (eye worm) hypothetical protein 0.0465 0.0439 0.1094
Echinococcus multilocularis lysine specific demethylase 5A 0.0446 0.0419 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Schistosoma mansoni caspase-7 (C14 family) 0.045 0.0424 0.0424
Loa Loa (eye worm) MBCTL1 0.0054 0.0013 0.0032
Brugia malayi MH2 domain containing protein 0.0051 0.001 0.0025
Mycobacterium ulcerans glutaminase 0.0276 0.0243 0.2395
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0446 0.0419 0.0419
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0255 0.0221 0.0552
Trypanosoma cruzi importin beta-1 subunit, putative 0.0069 0.0028 0.0474
Echinococcus granulosus o acyltransferase membrane bound domain 0.0601 0.0581 0.0581
Onchocerca volvulus 0.0059 0.0018 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Schistosoma mansoni transient receptor potential channel 0.0062 0.0021 0.0021
Trichomonas vaginalis helicase, putative 0.0052 0.0011 0.0024
Trypanosoma brucei metacaspase 0.0135 0.0097 0.1641
Schistosoma mansoni hypothetical protein 0.0309 0.0278 0.0278
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0135 0.0097 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Schistosoma mansoni hypothetical protein 0.014 0.0102 0.0102
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0017 0.0038
Toxoplasma gondii propionate-CoA ligase 0.014 0.0102 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0054 0.0013 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.0165 0.0361
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.014 0.0102 0.0975
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0617 0.0597 0.1489
Leishmania major hypothetical protein, conserved 0.0446 0.0419 0.7129
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.0012 0.0012
Loa Loa (eye worm) Smad1 0.0051 0.001 0.0025
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0305 0.0273 0.0597
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.0052 0.0886
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0214 0.0178 0.0593
Loa Loa (eye worm) histone methyltransferase 0.0092 0.0052 0.013
Echinococcus granulosus methyl CpG binding domain protein 2 0.0053 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0119 0.008 0.0199
Treponema pallidum fructose-bisphosphate aldolase 0.2047 0.2082 1
Echinococcus granulosus cpg binding protein 0.025 0.0216 0.0216
Loa Loa (eye worm) MBOAT family protein 0.0601 0.0581 0.1447
Schistosoma mansoni hypothetical protein 0.015 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.3286 0.3368 0.3368
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0601 0.0581 0.0581
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.014 0.0102 0.0332
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0046 0.0102
Echinococcus granulosus o acyltransferase membrane bound domain 0.0601 0.0581 0.0581
Leishmania major hypothetical protein, conserved 0.0051 0.001 0.0169
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0326 0.0295 0.0295
Brugia malayi jmjC domain containing protein 0.0119 0.008 0.0199
Onchocerca volvulus 0.0623 0.0604 0.1315
Echinococcus granulosus survival motor neuron protein 1 0.1184 0.1186 0.1186
Loa Loa (eye worm) steroid hormone receptor 0.0059 0.0018 0.0045
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0059 0.0017 0.0043
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0453 0.0426 0.1063
Echinococcus multilocularis tumor protein p63 0.3175 0.3252 0.3252
Echinococcus multilocularis musashi 0.0081 0.0041 0.0041
Echinococcus multilocularis L aminoadipate semialdehyde 0.0169 0.0132 0.0132
Schistosoma mansoni smad1 5 8 and 0.0051 0.001 0.001
Echinococcus granulosus chromobox protein 1 0.0358 0.0328 0.0328
Entamoeba histolytica hypothetical protein 0.0656 0.0637 0.3062
Toxoplasma gondii hypothetical protein 0.0601 0.0581 0.1582
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0104 0.0228
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0135 0.0097 0.0263
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0601 0.0581 0.0581
Echinococcus multilocularis chromobox protein 1 0.0358 0.0328 0.0328
Schistosoma mansoni caspase-7 (C14 family) 0.0357 0.0327 0.0327
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0122 0.0304
Mycobacterium ulcerans lipase LipD 0.0446 0.0419 0.4181
Echinococcus granulosus expressed conserved protein 0.0558 0.0536 0.0536
Brugia malayi photoreceptor-specific nuclear receptor 0.0059 0.0018 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.039
Echinococcus granulosus Chromobox protein 3 0.0059 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0143 0.0105 0.0105
Entamoeba histolytica hypothetical protein 0.0656 0.0637 0.3062
Loa Loa (eye worm) hypothetical protein 0.0124 0.0085 0.0212
Echinococcus granulosus beta LACTamase domain containing family member 0.0446 0.0419 0.0419
Toxoplasma gondii HEAT repeat-containing protein 0.0085 0.0045 0.0121
Schistosoma mansoni retinoic acid receptor RXR 0.0059 0.0018 0.0018
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0059 0.0017 0.0017
Echinococcus multilocularis zinc finger protein 0.0077 0.0036 0.0036
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0064 0.0023 0.0023
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0357 0.0327 0.1106
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0064 0.0023 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0041 0.0102
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.028 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0478 0.0453 0.1129
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0018 0.0018
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0054 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0118 0.0079 0.0198
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.0018 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0059 0.0018 0.0045
Loa Loa (eye worm) diacylglycerol acyltransferase 0.3578 0.3671 0.9149
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Trichomonas vaginalis conserved hypothetical protein 0.0601 0.0581 0.127
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0011 0.0024
Mycobacterium leprae conserved hypothetical protein 0.0446 0.0419 0.4181
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.014 0.0102 0.0975
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0446 0.0419 0.0419
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.028 0.0247 0.4202
Echinococcus multilocularis neuropeptide s receptor 0.1381 0.139 0.139
Brugia malayi intermediate filament protein 0.0081 0.0041 0.0102
Trypanosoma cruzi glycerol uptake protein, putative 0.0601 0.0581 0.9874
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0006 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0446 0.0419 0.7129
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0288 0.0256 0.0256
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0269 0.2663
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0095 0.0055 0.015
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0326 0.0295 0.0803
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.028 0.0247 0.0247
Schistosoma mansoni chromobox protein 0.0059 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.014 0.0102 0.0332
Mycobacterium tuberculosis Conserved protein 0.0446 0.0419 0.1422
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0053 0.0011 0.0011
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.016 0.016
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0041 0.0102
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.3578 0.3671 0.3671
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0143 0.0105 0.0105
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0023 0.039
Entamoeba histolytica hypothetical protein 0.0059 0.0017 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0059 0.0018 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0091 0.0091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0118 0.0079 0.0079
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.014 0.0102 0.0975
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Echinococcus multilocularis geminin 0.1029 0.1024 0.1024
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0072 0.0031 0.0086
Loa Loa (eye worm) hypothetical protein 0.0315 0.0284 0.0707
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Brugia malayi Smad1 0.0051 0.001 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.1 0.0995 1
Loa Loa (eye worm) hhat protein 0.0601 0.0581 0.1447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0059 0.0018 0.0045
Echinococcus multilocularis jumonji domain containing 1A 0.0119 0.008 0.008
Brugia malayi TAR-binding protein 0.0129 0.0091 0.0227
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.014 0.0102 0.1739
Schistosoma mansoni aldehyde dehydrogenase 0.0301 0.0269 0.0269
Brugia malayi MBOAT family protein 0.0601 0.0581 0.1447
Loa Loa (eye worm) hypothetical protein 0.0163 0.0126 0.0315
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0012 0.0206
Onchocerca volvulus Bile acid receptor homolog 0.0059 0.0018 0.0034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0054 0.0013 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Schistosoma mansoni coup transcription factor 0.0059 0.0018 0.0018
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.8982
Loa Loa (eye worm) hypothetical protein 0.0255 0.0221 0.0552
Entamoeba histolytica hypothetical protein 0.0059 0.0017 0.0083
Schistosoma mansoni hypothetical protein 0.0143 0.0105 0.0105
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.1 0.0995 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0013 0.022
Onchocerca volvulus 0.0446 0.0419 0.0911
Schistosoma mansoni protein phosphatase 2C 0.0119 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.006 0.0018 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.0059 0.0018 0.0045
Brugia malayi hypothetical protein 0.0656 0.0637 0.1589
Loa Loa (eye worm) hypothetical protein 0.0309 0.0278 0.0692
Toxoplasma gondii hypothetical protein 0.0112 0.0073 0.0199
Schistosoma mansoni hypothetical protein 0.0242 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0148 0.011 0.0275
Schistosoma mansoni hypothetical protein 0.0047 0.0005 0.0005
Brugia malayi CHE-14 protein 0.0255 0.0221 0.0552
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0357 0.0327 1
Trypanosoma cruzi hypothetical protein, conserved 0.0446 0.0419 0.7129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0083 0.0042 0.0042
Echinococcus granulosus ubiquitin specific protease 41 0.0054 0.0013 0.0013
Mycobacterium tuberculosis Conserved hypothetical protein 0.032 0.0289 0.0975
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0446 0.0419 0.1422
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0143 0.0105 0.0262
Echinococcus multilocularis peregrin 0.0135 0.0096 0.0096
Schistosoma mansoni importin beta-1 0.0085 0.0045 0.0045
Echinococcus granulosus ecdysone induced protein 78C 0.0059 0.0018 0.0018
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0201 0.0165 0.0411
Brugia malayi Probable ClpP-like protease 0.0326 0.0295 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0221 0.0484
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0183 0.0146 0.0399
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0478 0.0453 0.1538
Trichomonas vaginalis antibiotic synthetase, putative 0.014 0.0102 0.0224
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0085 0.0232
Schistosoma mansoni chromobox protein 0.0059 0.0017 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.0256 0.0256
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.001 0.0169
Echinococcus multilocularis importin subunit beta 1 0.0085 0.0045 0.0045
Schistosoma mansoni phosphatidylserine receptor 0.0119 0.008 0.008
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0059 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Loa Loa (eye worm) hypothetical protein 0.0601 0.0581 0.1447
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.014 0.0102 0.0332
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0078 0.0037 0.0037
Mycobacterium tuberculosis Probable hydrolase 0.0446 0.0419 0.1422
Echinococcus multilocularis Chromo domain 0.0059 0.0017 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0478 0.0453 0.1129
Echinococcus multilocularis chromobox protein 2 0.0059 0.0017 0.0017
Echinococcus granulosus peptidase Clp S14 family 0.0214 0.0178 0.0178
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0006 0.01
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.014 0.0102 0.0975
Loa Loa (eye worm) runx1 0.0055 0.0014 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0054 0.0013 0.0028
Schistosoma mansoni RAR-like nuclear receptor 0.0059 0.0018 0.0018
Brugia malayi PHD-finger family protein 0.0124 0.0085 0.0212
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0013 0.0036
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0357 0.0327 0.0327
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0135 0.0097 0.0097
Onchocerca volvulus Cell death protein 3 homolog 0.045 0.0424 0.0921
Loa Loa (eye worm) AMP-binding enzyme family protein 0.014 0.0102 0.0255
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0197 0.0161 0.2743
Onchocerca volvulus 0.0092 0.0052 0.0108
Loa Loa (eye worm) hypothetical protein 0.0157 0.012 0.0299
Loa Loa (eye worm) hypothetical protein 0.0313 0.0281 0.07
Entamoeba histolytica hypothetical protein 0.0601 0.0581 0.279
Echinococcus multilocularis thyroid hormone receptor alpha 0.02 0.0164 0.0164
Brugia malayi MH1 domain containing protein 0.0051 0.001 0.0025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.3907 0.4012 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.0018 0.0045
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0112 0.0073 0.0324
Echinococcus granulosus caspase 8 0.0135 0.0097 0.0097
Schistosoma mansoni cpg binding protein 0.025 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0242 0.0207 0.0517
Echinococcus granulosus sterol O acyltransferase 1 0.0601 0.0581 0.0581
Echinococcus multilocularis tar DNA binding protein 0.0129 0.0091 0.0091
Brugia malayi jmjC domain containing protein 0.0119 0.008 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Trichomonas vaginalis esterase, putative 0.0446 0.0419 0.0917
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0059 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0119 0.008 0.0199
Echinococcus granulosus neuropeptide receptor A26 0.1381 0.139 0.139
Trypanosoma cruzi metacaspase 5, putative 0.0135 0.0097 0.1641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.014 0.0102 0.0279
Trypanosoma cruzi polo-like protein kinase, putative 0.0288 0.0256 0.435
Loa Loa (eye worm) hypothetical protein 0.0218 0.0183 0.0456
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0565 0.0543 0.1478
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0083 0.0042 0.0042
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0012 0.0206
Trypanosoma cruzi metacaspase, putative 0.0135 0.0097 0.1641
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0023 0.0391
Mycobacterium tuberculosis Probable esterase LipL 0.0446 0.0419 0.1422
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0059 0.0018 0.0018
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.014 0.0102 0.0279
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0059 0.0017 0.0047
Loa Loa (eye worm) hypothetical protein 0.0478 0.0453 0.1129
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0011 0.0011
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0017 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.039
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0446 0.0419 0.1422
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0305 0.0273 0.0744
Echinococcus multilocularis PHD finger protein rhinoceros 0.0124 0.0085 0.0085
Brugia malayi hypothetical protein 0.0089 0.0049 0.0122
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.001 0.001
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0013 0.0013
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0301 0.0269 0.4576
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0017 0.0047
Brugia malayi beta-lactamase family protein 0.0446 0.0419 0.1045
Loa Loa (eye worm) hypothetical protein 0.0092 0.0052 0.0129
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0021 0.0021
Brugia malayi hypothetical protein 0.0059 0.0017 0.0043
Toxoplasma gondii isocitrate dehydrogenase 0.0064 0.0023 0.0063
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0197 0.0161 0.0775
Echinococcus granulosus lysine specific demethylase 5A 0.0465 0.0439 0.0439
Schistosoma mansoni hypothetical protein 0.0143 0.0105 0.0105
Trypanosoma cruzi GUP1, putative 0.0601 0.0581 0.9874
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.028 0.0247 0.244
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0119 0.008 0.0218
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0072 0.0031 0.0031
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0006 0.0016
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.014 0.0102 0.1739
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.014 0.0102 0.1739
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0305 0.0273 0.0597
Schistosoma mansoni sterol O-acyltransferase 1 0.0601 0.0581 0.0581
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0201 0.0165 0.0355
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0601 0.0581 0.0581
Echinococcus granulosus PHD finger protein rhinoceros 0.0124 0.0085 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0446 0.0419 0.0917
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.3578 0.3671 1
Schistosoma mansoni phd/f-box containing protein 0.0119 0.008 0.008
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0064 0.0023 0.0391
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0059 0.0017 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0031 0.0252
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0091 0.0091
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0085 0.0232
Schistosoma mansoni smad1 5 8 and 0.0051 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0565 0.0543 0.0543
Onchocerca volvulus 0.0157 0.012 0.0256
Onchocerca volvulus 0.0081 0.0041 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0013 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0041 0.0102
Brugia malayi Bromodomain containing protein 0.0135 0.0096 0.024
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0122 0.0122
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0135 0.0097 0.0241
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0023 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0059 0.0018 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0216 0.0181 0.0395
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.028 0.0247 0.1162
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0197 0.0161 0.2743
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Echinococcus multilocularis transient receptor potential ion channel A 0.0091 0.0051 0.0051
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0601 0.0581 0.0581
Onchocerca volvulus 0.014 0.0102 0.0218
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0012 0.0027
Loa Loa (eye worm) MH2 domain-containing protein 0.0754 0.074 0.1843
Echinococcus multilocularis ecdysone induced protein 78C 0.0059 0.0018 0.0018
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0604 0.0583 0.0583
Echinococcus granulosus geminin 0.1029 0.1024 0.1024
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0081 0.004 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0338 0.0307 0.1037
Echinococcus multilocularis survival motor neuron protein 1 0.1184 0.1186 0.1186
Toxoplasma gondii hypothetical protein 0.0098 0.0058 0.0159
Brugia malayi Pre-SET motif family protein 0.3907 0.4012 1
Brugia malayi Bromodomain containing protein 0.0122 0.0083 0.0206
Loa Loa (eye worm) hypothetical protein 0.0601 0.0581 0.1447
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0012 0.003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0595 0.0574 0.2756
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0092 0.0052 0.0052
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0054 0.0013 0.022
Mycobacterium ulcerans acyl-CoA synthetase 0.0478 0.0453 0.4522
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0111 0.0072 0.0157
Onchocerca volvulus 0.0242 0.0207 0.0447
Trichomonas vaginalis importin beta-1, putative 0.0069 0.0028 0.0061
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0326 0.0295 0.2922
Brugia malayi PHD-finger family protein 0.006 0.0018 0.0046
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0055 0.0013 0.0036
Brugia malayi jmjC domain containing protein 0.0119 0.008 0.0199
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0201 0.0165 0.0165
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0064 0.0023 0.0063
Giardia lamblia PHD finger protein 15 0.0124 0.0085 0.0408
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.001 0.0169
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.014 0.0102 0.0975
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0269 0.2663
Onchocerca volvulus 0.0059 0.0017 0.0032
Leishmania major hypothetical protein, conserved 0.0601 0.0581 0.9874
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0656 0.0637 0.0637
Echinococcus granulosus caspase 0.0357 0.0327 0.0327
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0288 0.0256 0.0256
Plasmodium vivax JmjC domain containing protein 0.0119 0.008 0.0218
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.01 0.01
Loa Loa (eye worm) CHromoDomain protein family member 0.0078 0.0037 0.0092
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0064 0.0023 0.0059
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Loa Loa (eye worm) CXXC zinc finger family protein 0.0231 0.0196 0.0488
Schistosoma mansoni hypothetical protein 0.0124 0.0085 0.0085
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0054 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Loa Loa (eye worm) hypothetical protein 0.0092 0.0052 0.013
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0601 0.0581 0.1447
Onchocerca volvulus 0.0231 0.0196 0.0423
Onchocerca volvulus 0.014 0.0102 0.0218
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0059 0.0017 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0288 0.0255 0.4343
Echinococcus granulosus lamin 0.0081 0.0041 0.0041
Brugia malayi hypothetical protein 0.0051 0.001 0.0025
Schistosoma mansoni hypothetical protein 0.0905 0.0896 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0012 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0087 0.0046 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0012 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0478 0.0453 0.4522
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0105 0.0229
Schistosoma mansoni alpha-glucosidase 0.0137 0.0099 0.0099
Echinococcus multilocularis Protein lozenge 0.0055 0.0014 0.0014
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0108 0.0068 0.017
Mycobacterium ulcerans hypothetical protein 0.032 0.0289 0.2866
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0023 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.014 0.0102 0.0255
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0091 0.0091
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0091 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0059 0.0018 0.0045
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0601 0.0581 0.0581
Trichomonas vaginalis D-aminoacylase, putative 0.0446 0.0419 0.0917
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Onchocerca volvulus 0.0441 0.0414 0.09
Brugia malayi chromobox protein homolog 3 0.0201 0.0165 0.0411
Onchocerca volvulus 0.0081 0.0041 0.0083
Echinococcus multilocularis transcription factor eb 0.0108 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.1184 0.1186 0.2956
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.014 0.0102 0.1739
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Trypanosoma cruzi GUP1, putative 0.0601 0.0581 0.9874
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0054 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0595 0.0574 0.143
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.001 0.0169
Plasmodium falciparum importin beta, putative 0.0085 0.0045 0.0121
Trypanosoma cruzi DNA polymerase eta, putative 0.0065 0.0024 0.0403
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.014 0.0102 0.0975
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Echinococcus multilocularis lamin 0.0081 0.0041 0.0041
Loa Loa (eye worm) latrophilin receptor protein 2 0.0143 0.0105 0.0262
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0002 0.0004
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0097 0.0057 0.0177
Echinococcus granulosus o acyltransferase membrane bound domain 0.0601 0.0581 0.0581
Echinococcus multilocularis Niemann Pick C1 protein 0.0595 0.0574 0.0574
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0104 0.0065 0.1101
Brugia malayi nuclear receptor NHR-88 0.0059 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0059 0.0018 0.0045
Brugia malayi Calcitonin receptor-like protein seb-1 0.0453 0.0426 0.1063
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0045 0.0757
Brugia malayi steroid hormone receptor 0.0059 0.0018 0.0045
Brugia malayi beta-lactamase family protein 0.0446 0.0419 0.1045
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0006 0.0016
Leishmania major glycerol uptake protein, putative 0.0601 0.0581 0.9874
Brugia malayi CXXC zinc finger family protein 0.0231 0.0196 0.0488
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0305 0.0273 0.0597
Schistosoma mansoni eyes absent homolog 0.0089 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0601 0.0581 0.1447
Mycobacterium ulcerans acetyl-CoA synthetase 0.014 0.0102 0.0975
Leishmania major glycerol uptake protein, putative 0.0601 0.0581 0.9874
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0059 0.0017 0.0017
Brugia malayi mbt repeat family protein 0.0048 0.0006 0.0015
Trypanosoma cruzi metacaspase, putative 0.0135 0.0097 0.1641
Mycobacterium ulcerans acyl-CoA synthetase 0.014 0.0102 0.0975
Brugia malayi beta-lactamase 0.0446 0.0419 0.1045
Echinococcus multilocularis dnaJ subfamily B 0.3286 0.3368 0.3368
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0097 0.0211
Brugia malayi AMP-binding enzyme family protein 0.0478 0.0453 0.1129
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0601 0.0581 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0104 0.0228
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.014 0.0102 0.0332
Echinococcus multilocularis microtubule associated protein 2 0.9675 1 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0012 0.0058
Loa Loa (eye worm) hypothetical protein 0.0357 0.0327 0.0816
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Loa Loa (eye worm) hypothetical protein 0.0059 0.0017 0.0043
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0078 0.0037 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0338 0.0307 0.1037
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0357 0.0327 0.3253
Trichomonas vaginalis penicillin-binding protein, putative 0.0446 0.0419 0.0917
Trichomonas vaginalis chromobox protein, putative 0.0216 0.0181 0.0395
Loa Loa (eye worm) hypothetical protein 0.0089 0.0049 0.0122
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0112 0.0073 0.0199
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0023 0.0023
Echinococcus multilocularis sterol O acyltransferase 1 0.0601 0.0581 0.0581
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0124 0.0085 0.0085
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.039
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0169 0.0132 0.0132
Echinococcus multilocularis apoptotic protease activating factor 1 0.0315 0.0284 0.0284
Mycobacterium ulcerans acyl-CoA synthetase 0.0478 0.0453 0.4522
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0013 0.0013
Schistosoma mansoni lipoxygenase 0.0058 0.0017 0.0017
Brugia malayi jmjC domain containing protein 0.0465 0.0439 0.1094
Schistosoma mansoni cellular tumor antigen P53 0.0465 0.0439 0.0439
Trypanosoma brucei Metacaspase-4 0.0135 0.0097 0.1641
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.014 0.0102 0.0102
Echinococcus granulosus transient receptor potential ion channel A 0.0091 0.0051 0.0051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.0018 0.0045
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0059 0.0018 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0135 0.0097 0.0263
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0415 0.0387 0.0387
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0012 0.0206
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0059 0.0017 0.0017
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0119 0.008 0.0218
Onchocerca volvulus Protein ultraspiracle homolog 0.0059 0.0018 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0617 0.0597 0.0597
Schistosoma mansoni aldehyde dehydrogenase 0.0301 0.0269 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0601 0.0581 0.127
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0539 0.0516 0.0516
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0415 0.0387 0.0387
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0059 0.0018 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0059 0.0018 0.0034
Schistosoma mansoni hypothetical protein 0.1029 0.1024 0.1024
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0045 0.0757
Leishmania major importin beta-1 subunit, putative 0.0069 0.0028 0.0474
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.014 0.0102 0.0332
Trypanosoma cruzi ISWI complex protein 0.0047 0.0005 0.0093
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0023 0.0391
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0478 0.0453 0.1538
Brugia malayi jmjC domain containing protein 0.0701 0.0685 0.1706
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0054 0.0013 0.0062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0415 0.0387 0.0387
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.001 0.001
Plasmodium falciparum acetyl-CoA synthetase, putative 0.014 0.0102 0.0279
Onchocerca volvulus 0.016 0.0122 0.0261
Plasmodium falciparum JmjC domain-containing protein, putative 0.0119 0.008 0.0218
Brugia malayi MH2 domain containing protein 0.0051 0.001 0.0025
Brugia malayi Importin beta-1 subunit 0.0085 0.0045 0.0111
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0415 0.0387 0.0965
Plasmodium falciparum metacaspase 1 0.0135 0.0097 0.0263
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0028 0.0061
Echinococcus multilocularis dna polymerase eta 0.0092 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0054 0.0013 0.0028
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.009 0.005 0.085
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0012 0.0012
Schistosoma mansoni survival motor neuron protein 0.0242 0.0207 0.0207
Echinococcus granulosus zinc finger protein 0.0077 0.0036 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0018 0.0018
Brugia malayi RNA, U transporter 1 0.0241 0.0207 0.0516
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0415 0.0387 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0301 0.0269 0.2663
Brugia malayi AMP-binding enzyme family protein 0.014 0.0102 0.0255
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0601 0.0581 0.127
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0064 0.0023 0.0063
Schistosoma mansoni patched 1 0.0255 0.0221 0.0221
Echinococcus multilocularis JmjC domain containing protein 4 0.0119 0.008 0.008
Schistosoma mansoni transcription factor LCR-F1 0.0656 0.0637 0.0637
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0092 0.0052 0.0249
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.014 0.0102 0.0332
Onchocerca volvulus 0.014 0.0102 0.0218
Loa Loa (eye worm) hypothetical protein 0.0143 0.0105 0.0262
Brugia malayi AMP-binding enzyme family protein 0.014 0.0102 0.0255
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0905 0.0896 0.2234
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0601 0.0581 0.279
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0135 0.0097 0.0211
Leishmania major glycerol uptake protein, putative 0.0601 0.0581 0.9874
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0415 0.0387 0.0965
Echinococcus multilocularis phd:f box containing protein 0.0119 0.008 0.008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0059 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Schistosoma mansoni chromobox protein 0.0358 0.0328 0.0328
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0011 0.0011
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0006 0.0015
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0291 0.0259 0.0645
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.039
Trypanosoma brucei acetyl-CoA synthetase, putative 0.014 0.0102 0.1739
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0085 0.0232
Echinococcus granulosus mixed lineage leukemia protein mll 0.0078 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0656 0.0637 0.3062
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0326 0.0295 0.0803
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0478 0.0453 0.4522
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0601 0.0581 0.0581
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.014 0.0102 0.0332
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0623 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.0059 0.0018 0.0045
Onchocerca volvulus 0.0048 0.0006 0.0007
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.3578 0.3671 1
Schistosoma mansoni DNA polymerase eta 0.0092 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0017 0.0038
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0201 0.0165 0.0165
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0059 0.0018 0.0045
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0008 0.0008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0065 0.0024 0.0065
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0453 0.0426 0.1063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2047 0.2082 0.4553
Leishmania major DNA polymerase eta, putative 0.0092 0.0052 0.0886
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0478 0.0453 0.4522
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0006 0.0006
Brugia malayi Niemann-Pick C1 protein precursor 0.0595 0.0574 0.143
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2047 0.2082 1
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0112 0.0279
Schistosoma mansoni hypothetical protein 0.0064 0.0023 0.0023
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.8982
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0017 0.0038
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0012 0.0012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0045 0.077
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.008 0.0199
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0111 0.0072 0.0072
Trypanosoma brucei metacaspase MCA3 0.0135 0.0097 0.1641
Schistosoma mansoni lamin 0.0081 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0656 0.0637 0.3062
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.014 0.0102 0.0332
Brugia malayi glutaminase DH11.1 0.0276 0.0243 0.0605
Schistosoma mansoni thyroid hormone receptor 0.02 0.0164 0.0164
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0111 0.0072 0.0157
Brugia malayi M-phase phosphoprotein, mpp8 0.0059 0.0017 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0288 0.0256 0.056
Trypanosoma cruzi glycerol uptake protein, putative 0.0601 0.0581 0.9874
Echinococcus granulosus Protein patched homolog 1 0.0255 0.0221 0.0221
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0138 0.01 0.01
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0006 0.01
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0326 0.0295 0.0803
Brugia malayi RNA binding protein 0.0129 0.0091 0.0227
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0091 0.0091
Echinococcus multilocularis beta LACTamase domain containing family member 0.0446 0.0419 0.0419
Schistosoma mansoni transient receptor potential channel 4 0.0094 0.0055 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.051 0.0486 0.0486
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.0052 0.013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0119 0.008 0.1359
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.0102 0.0102
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0122 0.0122
Treponema pallidum alginate O-acetylation protein (algI) 0.0601 0.0581 0.277
Trypanosoma brucei metacaspase 5, putative 0.0135 0.0097 0.1641
Loa Loa (eye worm) hypothetical protein 0.0446 0.0419 0.1045
Entamoeba histolytica vacuolar protein sorting 26 0.0601 0.0581 0.279
Leishmania major glycerol uptake protein, putative 0.0601 0.0581 0.9874
Schistosoma mansoni hypothetical protein 0.0315 0.0284 0.0284
Echinococcus granulosus tar DNA binding protein 0.0129 0.0091 0.0091
Loa Loa (eye worm) MBOAT family protein 0.0601 0.0581 0.1447
Echinococcus granulosus intermediate filament protein 0.0081 0.0041 0.0041
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0326 0.0295 0.0295
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0326 0.0295 0.0803
Entamoeba histolytica acyl-coA synthetase, putative 0.0478 0.0453 0.2176
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0017 0.0083
Loa Loa (eye worm) acetyltransferase 0.015 0.0112 0.0279
Mycobacterium ulcerans acyl-CoA synthetase 0.0478 0.0453 0.4522
Leishmania major metacaspase, putative 0.0135 0.0097 0.1641
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0059 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0078 0.0037 0.0037

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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