Detailed information for compound 656423

Basic information

Technical information
  • TDR Targets ID: 656423
  • Name: 2-(5,6-dimethyl-4-oxo-3-prop-2-enylthieno[2,3 -d]pyrimidin-2-yl)sulfanyl-N-(3-hydroxypropyl )acetamide
  • MW: 367.486 | Formula: C16H21N3O3S2
  • H donors: 2 H acceptors: 3 LogP: 2.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCCNC(=O)CSc1nc2sc(c(c2c(=O)n1CC=C)C)C
  • InChi: 1S/C16H21N3O3S2/c1-4-7-19-15(22)13-10(2)11(3)24-14(13)18-16(19)23-9-12(21)17-6-5-8-20/h4,20H,1,5-9H2,2-3H3,(H,17,21)
  • InChiKey: SMKBROLEMDVSQL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(3-allyl-5,6-dimethyl-4-oxo-thieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-(3-hydroxypropyl)acetamide
  • 2-[(3-allyl-5,6-dimethyl-4-oxo-2-thieno[2,3-d]pyrimidinyl)thio]-N-(3-hydroxypropyl)acetamide
  • 2-[(3-allyl-4-keto-5,6-dimethyl-thieno[2,3-d]pyrimidin-2-yl)thio]-N-(3-hydroxypropyl)acetamide
  • 2-(5,6-dimethyl-4-oxo-3-prop-2-enyl-thieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-(3-hydroxypropyl)ethanamide
  • STOCK1S-71812
  • ZINC02083102
  • BAS 02072497
  • CBMicro_031384
  • BIM-0031603.P001
  • AF-399/14425119

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0056 0.028
Onchocerca volvulus Tyrosine kinase homolog 0.0141 0.0178 0.178
Brugia malayi Calcitonin receptor-like protein seb-1 0.0203 0.0268 0.134
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0051 0.0049 0.0049
Onchocerca volvulus 0.0032 0.0023 0.0205
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0772 0.1088 0.544
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0002 0.0002
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0049 0.0046 0.0005
Echinococcus multilocularis epidermal growth factor receptor 0.0311 0.0424 0.0424
Echinococcus granulosus insulin receptor 0.0186 0.0244 0.0244
Brugia malayi beta-lactamase family protein 0.007 0.0077 0.0385
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0007
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0032 0.0023 0.0023
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0079 0.0394
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0077 0.1622
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0048 0.0967
Echinococcus granulosus heat shock protein 90 0.0043 0.0038 0.0038
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0002 0.0002
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0022 0.0008 0.0008
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0005 0.0023
Toxoplasma gondii propionate-CoA ligase 0.0049 0.0046 0.1682
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Entamoeba histolytica cysteine protease, putative 0.005 0.0048 0.1002
Brugia malayi Papain family cysteine protease containing protein 0.005 0.0048 0.0239
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0046 0.0024
Loa Loa (eye worm) hypothetical protein 0.0124 0.0154 0.0771
Onchocerca volvulus 0.0133 0.0168 0.1673
Loa Loa (eye worm) isocitrate dehydrogenase 0.0051 0.0049 0.0247
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0005 0.0005
Plasmodium vivax vivapain-2 0.005 0.0048 0.1526
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0077 0.1622
Echinococcus granulosus PHD finger protein rhinoceros 0.0119 0.0148 0.0148
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Brugia malayi Bromodomain containing protein 0.0111 0.0136 0.0678
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0051 0.0049 0.0033
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0015 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0077 0.1622
Loa Loa (eye worm) heat shock protein 90 0.005 0.0049 0.0243
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0119 0.0148 0.0148
Loa Loa (eye worm) TK/INSR protein kinase 0.0186 0.0244 0.1218
Mycobacterium leprae Probable lipase LipE 0.007 0.0077 0.0082
Onchocerca volvulus 0.0166 0.0214 0.2145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Echinococcus granulosus tar DNA binding protein 0.0069 0.0076 0.0076
Mycobacterium leprae conserved hypothetical protein 0.007 0.0077 0.0082
Echinococcus multilocularis histone acetyltransferase MYST2 0.0051 0.005 0.005
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0002 0.0002
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0152 0.0195 0.7673
Echinococcus granulosus endoplasmin 0.0047 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0032 0.0032
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.01 0.012 0.0208
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0032 0.0032
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0033 0.0033
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0043 0.0855
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0049 0.0046 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.0201 0.4395
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0077 0.0102
Brugia malayi PHD-finger family protein 0.0119 0.0148 0.0738
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0106 0.0106
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.014 0.0177 0.0177
Giardia lamblia Fructose-bisphosphate aldolase 0.0319 0.0436 1
Brugia malayi Hsp90 protein 0.0033 0.0024 0.0121
Schistosoma mansoni acetyl-CoA synthetase 0.0049 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Echinococcus granulosus jumonji domain containing protein 0.0166 0.0215 0.0215
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0253 0.0341 0.0341
Echinococcus granulosus sodium:glucose cotransporter 0.0032 0.0023 0.0023
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0049 0.1816
Brugia malayi GH02984p 0.0293 0.0399 0.1994
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0323 0.0442 0.1012
Schistosoma mansoni glutaminase 0.0599 0.0839 0.0839
Loa Loa (eye worm) TK/FAK protein kinase 0.0251 0.0337 0.1686
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Schistosoma mansoni sodium/solute symporter 0.0032 0.0023 0.0023
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0076 0.0378
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0207 0.0274 0.604
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0077 0.0668
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0047 0.0007
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Brugia malayi chromobox protein homolog 3 0.004 0.0034 0.0168
Loa Loa (eye worm) hypothetical protein 0.0041 0.0035 0.0177
Schistosoma mansoni cpg binding protein 0.0101 0.0122 0.0122
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0359 0.0494 0.1141
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0024 0.0024
Onchocerca volvulus 0.009 0.0106 0.105
Leishmania major heat shock protein, putative 0.0033 0.0024 0.0438
Mycobacterium ulcerans hypothetical protein 0.007 0.0077 0.0082
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Brugia malayi jmjC domain containing protein 0.0056 0.0056 0.028
Trypanosoma brucei glucosidase, putative 0.0039 0.0033 0.0633
Echinococcus granulosus lysine specific demethylase 5A 0.0219 0.0292 0.0292
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0124 0.0154 0.7245
Brugia malayi hypothetical protein 0.0484 0.0673 0.3364
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0049 0.0046 0.1682
Loa Loa (eye worm) hypothetical protein 0.0152 0.0195 0.0975
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Mycobacterium tuberculosis Probable oxidoreductase 0.0359 0.0494 0.1141
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0049 0.1001
Loa Loa (eye worm) hypothetical protein 0.0221 0.0295 0.1475
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0013 0.0194
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0156 0.0201 0.4395
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0049 0.0046 0.0024
Loa Loa (eye worm) fibroinase 0.005 0.0048 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0047 0.0943
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Schistosoma mansoni hypothetical protein 0.0155 0.02 0.02
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0047 0.0177
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0072 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0033 0.0261
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.005 0.0048 0.0239
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0013 0.0065
Loa Loa (eye worm) hypothetical protein 0.011 0.0134 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0047 0.0943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Brugia malayi Pre-SET motif family protein 0.0091 0.0106 0.0532
Toxoplasma gondii cathepsin CPL 0.005 0.0048 0.1754
Echinococcus multilocularis zinc finger protein 0.0062 0.0065 0.0065
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0051 0.005 0.0248
Brugia malayi jmjC domain containing protein 0.0219 0.0292 0.1458
Onchocerca volvulus 0.0049 0.0046 0.0441
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0077 0.0102
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0049 0.1018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0024 0.018
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0008 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Entamoeba histolytica serine/threonine protein kinase, putative 0.0207 0.0274 0.6255
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0028 0.014
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0002 0.0012
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0052 0.0051 0.1679
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0033 0.0261
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0166 0.0214 0.0426
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0116 0.0116
Onchocerca volvulus Matrilysin homolog 0.011 0.0134 0.133
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0033 0.0261
Schistosoma mansoni myelin transcription factor 1 myt1 0.0051 0.005 0.005
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0045 0.0041 0.0386
Schistosoma mansoni protein phosphatase 2C 0.0056 0.0056 0.0056
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1593 0.227 0.227
Trypanosoma brucei Heat shock protein 83, putative 0.005 0.0049 0.0983
Loa Loa (eye worm) hypothetical protein 0.011 0.0134 0.067
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Echinococcus granulosus chromobox protein 1 0.0071 0.0079 0.0079
Onchocerca volvulus 0.007 0.0077 0.0755
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0049 0.0046 0.1682
Onchocerca volvulus 0.007 0.0077 0.0755
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0011 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0002 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0113
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0049
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0115 0.0115
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0076 0.0378
Brugia malayi beta-lactamase 0.007 0.0077 0.0385
Brugia malayi hypothetical protein 0.1405 0.2 1
Schistosoma mansoni jumonji domain containing protein 0.0374 0.0515 0.0515
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0046 0.0024
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0049 0.0046 0.0046
Echinococcus multilocularis solute carrier family 5 0.0032 0.0023 0.0023
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0455 0.0631 0.0631
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.062 0.0868 0.4342
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0178 0.0232 0.0232
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.2823 0.4042 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0002 0.0012
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0013 0.0188
Mycobacterium ulcerans hydrolase 0.0134 0.0168 0.0311
Entamoeba histolytica acyl-CoA synthetase, putative 0.0166 0.0214 0.4868
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Brugia malayi glutathione reductase 0.0142 0.018 0.0901
Schistosoma mansoni chromobox protein 0.0071 0.0079 0.0079
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0046 0.023
Loa Loa (eye worm) hypothetical protein 0.0124 0.0154 0.0771
Schistosoma mansoni kinase 0.0105 0.0128 0.0128
Leishmania major 4-coumarate:coa ligase-like protein 0.0166 0.0214 0.47
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0002 0.0012
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0049 0.0046 0.023
Brugia malayi RNA binding protein 0.0069 0.0076 0.0378
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0056 0.0056 0.209
Brugia malayi beta-lactamase family protein 0.007 0.0077 0.0385
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0049 0.1816
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0072 0.2717
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0047 0.0007
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0455 0.0631 0.0631
Onchocerca volvulus Serine\/threonine kinase homolog 0.0207 0.0274 0.275
Loa Loa (eye worm) hypothetical protein 0.005 0.0048 0.0239
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0022 0.0008 0.0008
Schistosoma mansoni high-affinity choline transporter 0.0293 0.0399 0.0399
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0072 0.1498
Echinococcus multilocularis peregrin 0.0126 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.0046 0.023
Trypanosoma cruzi cruzipain precursor, putative 0.019 0.025 0.5487
Onchocerca volvulus Glucosylceramidase homolog 0.0506 0.0706 0.711
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.01 0.012 0.0208
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0005 0.0001
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0035 0.0035
Loa Loa (eye worm) endoplasmin 0.005 0.0049 0.0243
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0018 0.0288
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0047 0.0177
Loa Loa (eye worm) mbt repeat family protein 0.0045 0.0041 0.0203
Schistosoma mansoni phd/f-box containing protein 0.0056 0.0056 0.0056
Entamoeba histolytica acyl-coA synthetase, putative 0.0166 0.0214 0.4868
Loa Loa (eye worm) hypothetical protein 0.0056 0.0056 0.028
Echinococcus granulosus phd:f box containing protein 0.0056 0.0056 0.0056
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0148 0.581
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.2823 0.4042 1
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0033 0.0024 0.022
Trypanosoma cruzi heat shock protein, putative 0.0033 0.0024 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0024 0.018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0066 0.0071 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.0177 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0064 0.0068 0.0068
Echinococcus multilocularis fetal alzheimer antigen, falz 0.007 0.0077 0.0077
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0046 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0119 0.0148 0.5694
Echinococcus granulosus cathepsin l cysteine peptidase 0.005 0.0048 0.0048
Toxoplasma gondii heat shock protein 75, putative 0.0033 0.0024 0.0794
Brugia malayi cathepsin L-like precursor 0.0033 0.0024 0.012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0013 0.0013
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0002 0.0012
Echinococcus granulosus protein kinase c iota type 0.009 0.0105 0.0105
Plasmodium vivax JmjC domain containing protein 0.0056 0.0056 0.1871
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0072 0.0072
Loa Loa (eye worm) beta-lactamase 0.007 0.0077 0.0385
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0186 0.0244 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Schistosoma mansoni tyrosine kinase 0.0306 0.0417 0.0417
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0047 0.1481
Schistosoma mansoni tyrosine kinase 0.0311 0.0424 0.0424
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0046 0.0927
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0177 0.023 0.023
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.0201 0.4395
Loa Loa (eye worm) hypothetical protein 0.0118 0.0146 0.0729
Mycobacterium ulcerans acyl-CoA synthetase 0.0166 0.0214 0.0426
Echinococcus multilocularis serine protein kinase ATM 0.0027 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0013 0.0188
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0076 0.0076
Echinococcus granulosus cpg binding protein 0.0101 0.0122 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Plasmodium falciparum heat shock protein 90, putative 0.0191 0.0251 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0359 0.0494 0.1141
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0076 0.0076
Schistosoma mansoni jumonji/arid domain-containing protein 0.0219 0.0292 0.0292
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0013 0.0194
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0166 0.0214 0.0426
Brugia malayi TAR-binding protein 0.0069 0.0076 0.0378
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0035 0.0174
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.0005 0.0005
Leishmania major acetyl-CoA synthetase, putative 0.0049 0.0046 0.0927
Plasmodium falciparum cysteine proteinase falcipain 3 0.005 0.0048 0.1526
Schistosoma mansoni lozenge 0.0061 0.0063 0.0063
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0038 0.036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Loa Loa (eye worm) hypothetical protein 0.0041 0.0035 0.0174
Onchocerca volvulus Matrilysin homolog 0.0243 0.0326 0.3275
Echinococcus granulosus sodium:glucose cotransporter 2 0.0032 0.0023 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0069 0.0069
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0144 0.027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Echinococcus granulosus epidermal growth factor receptor 0.0577 0.0808 0.0808
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0049 0.0046 0.1451
Echinococcus granulosus cathepsin L cysteine proteinase 0.005 0.0048 0.0048
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0005 0.0005
Onchocerca volvulus 0.0049 0.0046 0.0441
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0124 0.0154 0.0771
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0287 0.0389 0.1944
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0073 0.0367
Onchocerca volvulus Matrix metalloproteinase homolog 0.0243 0.0326 0.3275
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0072 0.0088
Schistosoma mansoni alpha-glucosidase 0.0153 0.0197 0.0197
Mycobacterium ulcerans hypothetical protein 0.0166 0.0214 0.0426
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0049 0.0046 0.0927
Brugia malayi MH2 domain containing protein 0.0245 0.0328 0.1642
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0195 0.7735
Brugia malayi F/Y-rich N-terminus family protein 0.0075 0.0085 0.0423
Brugia malayi nuclear receptor NHR-88 0.0018 0.0002 0.0012
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0049 0.0046 0.0024
Leishmania major 4-coumarate:coa ligase-like protein 0.0166 0.0214 0.47
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0051 0.005 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Echinococcus multilocularis heat shock protein 90 0.0043 0.0038 0.0038
Brugia malayi Protein kinase domain containing protein 0.0251 0.0337 0.1686
Loa Loa (eye worm) hypothetical protein 0.0096 0.0115 0.0573
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0032 0.0616
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0079 0.0685
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Loa Loa (eye worm) hypothetical protein 0.0124 0.0154 0.0771
Onchocerca volvulus 0.0049 0.0046 0.0441
Loa Loa (eye worm) jmjC domain-containing protein 0.0219 0.0292 0.1458
Loa Loa (eye worm) hypothetical protein 0.0484 0.0673 0.3364
Loa Loa (eye worm) CHromoDomain protein family member 0.0022 0.0008 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0044 0.0364
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0448 0.0621 0.1461
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0203 0.0268 0.134
Brugia malayi jmjC domain containing protein 0.0056 0.0056 0.028
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0035 0.0035
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0013 0.0194
Loa Loa (eye worm) hypothetical protein 0.1405 0.2 1
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0035 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0005 0.0023
Schistosoma mansoni heat shock protein 0.005 0.0049 0.0049
Plasmodium falciparum glutathione reductase 0.0049 0.0047 0.1481
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0106
Echinococcus granulosus jumonji domain containing 1A 0.0056 0.0056 0.0056
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0077 0.0077
Mycobacterium tuberculosis Probable dehydrogenase 0.0323 0.0442 0.1012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0049 0.0049
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0002 0.0012
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0047 0.0044 0.0883
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0087 0.0102 0.0509
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0049 0.0046 0.0024
Loa Loa (eye worm) hypothetical protein 0.0166 0.0214 0.1072
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0049 0.0049
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0049 0.0046 0.0927
Echinococcus granulosus methyl CpG binding domain protein 2 0.0049 0.0047 0.0047
Loa Loa (eye worm) cysteine protease 0.005 0.0048 0.0239
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Brugia malayi hypothetical protein 0.0253 0.0341 0.1705
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0124 0.0154 0.0275
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0002 0.0002
Brugia malayi AF-10 protein 0.0039 0.0032 0.016
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0166 0.0214 0.0426
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Plasmodium vivax endoplasmin, putative 0.005 0.0049 0.1555
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0022 0.0164
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0034 0.0316
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0013 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0174 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Echinococcus multilocularis lysine specific demethylase 6a 0.0056 0.0056 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0002 0.0002
Trypanosoma cruzi polo-like protein kinase, putative 0.0207 0.0274 0.604
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0046 0.023
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0006
Plasmodium falciparum phd finger protein, putative 0.0119 0.0148 0.5694
Entamoeba histolytica hypothetical protein 0.0253 0.0341 0.7802
Trichomonas vaginalis helicase, putative 0.002 0.0005 0.0008
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0049 0.0046 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.0436 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0577 0.0808 0.4039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0002 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.0436 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0168 0.0842
Giardia lamblia Grp94/Hsp90 0.0047 0.0044 0.0915
Echinococcus granulosus survival motor neuron protein 1 0.1405 0.2 0.2
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0077 0.0102
Plasmodium vivax heat shock protein 90, putative 0.0033 0.0024 0.0539
Entamoeba histolytica hypothetical protein 0.0027 0.0015 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0002 0.0012
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0186 0.0244 0.0244
Echinococcus multilocularis lysine specific demethylase 5A 0.0208 0.0276 0.0276
Echinococcus multilocularis heat shock protein 0.005 0.0049 0.0049
Brugia malayi heat shock protein 90 0.005 0.0049 0.0243
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0051 0.0049 0.1001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0076 0.0076
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0033 0.0655
Brugia malayi Isocitrate dehydrogenase 0.0051 0.0049 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Schistosoma mansoni sex comb on midleg homolog 0.0045 0.0041 0.0041
Echinococcus multilocularis protein dispatched 1 0.0047 0.0044 0.0044
Brugia malayi PHD-finger family protein 0.0077 0.0087 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0049 0.0047 0.0047
Leishmania major mitochondrial DNA polymerase beta 0.033 0.0451 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0002 0.0012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0002 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0035 0.0702
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0047 0.0943
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0232 0.0232
Echinococcus granulosus dnaJ subfamily B 0.1287 0.183 0.183
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0062 0.031
Echinococcus granulosus fetal alzheimer antigen falz 0.007 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0039 0.0032 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0124 0.11
Brugia malayi Matrixin family protein 0.011 0.0134 0.067
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0772 0.1088 0.544
Plasmodium vivax glutathione reductase, putative 0.0142 0.018 0.7049
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0032 0.0616
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0359 0.0494 0.1124
Giardia lamblia Heat shock protein HSP 90-alpha 0.005 0.0049 0.1018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0049 0.0244
Brugia malayi jmjC domain containing protein 0.0455 0.0631 0.3154
Schistosoma mansoni tyrosine kinase 0.0306 0.0417 0.0417
Schistosoma mansoni hypothetical protein 0.0253 0.0341 0.0341
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0123 0.0123
Onchocerca volvulus 0.0484 0.0673 0.6778
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0049 0.0983
Schistosoma mansoni coup transcription factor 0.0018 0.0002 0.0002
Onchocerca volvulus Cathepsin L homolog 0.005 0.0048 0.0459
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0072 0.0072
Brugia malayi glutaminase DH11.1 0.0599 0.0839 0.4193
Echinococcus granulosus heat shock protein 0.005 0.0049 0.0049
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0077 0.0102
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0043 0.0855
Brugia malayi isocitrate dehydrogenase 0.0051 0.0049 0.0247
Mycobacterium ulcerans transcriptional regulator 0.2823 0.4042 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0049 0.0046 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0002 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0013 0.0194
Mycobacterium ulcerans TetR family transcriptional regulator 0.2823 0.4042 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Echinococcus multilocularis heat shock protein 90 0.005 0.0049 0.0049
Echinococcus granulosus expressed conserved protein 0.009 0.0106 0.0106
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0399 0.055 0.055
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0049 0.0983
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0168
Plasmodium falciparum cysteine proteinase falcipain 2a 0.005 0.0048 0.1526
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0049 0.0983
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0035 0.0678
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0035 0.028
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0052 0.0051 0.0189
Mycobacterium tuberculosis Conserved protein 0.007 0.0077 0.0102
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0035 0.0035
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0115 0.2551
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.001 0.0116
Plasmodium falciparum thioredoxin reductase 0.0142 0.018 0.7049
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0049 0.0046 0.0927
Echinococcus granulosus cathepsin l1 0.005 0.0048 0.0048
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0106 0.4136
Loa Loa (eye worm) glutathione reductase 0.0142 0.018 0.0901
Schistosoma mansoni sex comb on midleg homolog 0.0045 0.0041 0.0041
Echinococcus granulosus sodium:myo inositol cotransporter 0.0032 0.0023 0.0023
Brugia malayi jmjC domain containing protein 0.0056 0.0056 0.028
Echinococcus multilocularis Protein lozenge 0.0061 0.0063 0.0063
Echinococcus multilocularis SAM and MBT domain containing protein 0.0045 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0056 0.0056 0.028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0056 0.0056 0.1153
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0034 0.0268
Echinococcus multilocularis jumonji domain containing 1A 0.0056 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0015 0.0099
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0047 0.1481
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0046 0.0024
Onchocerca volvulus 0.005 0.0048 0.0459
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0148 0.581
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Onchocerca volvulus 0.0049 0.0046 0.0441
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0002 0.0002
Trypanosoma brucei heat shock protein 84, putative 0.0033 0.0024 0.0438
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0006 0.0017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0035 0.0035
Brugia malayi Cathepsin L-like precursor 0.0033 0.0024 0.012
Entamoeba histolytica hypothetical protein 0.0253 0.0341 0.7802
Loa Loa (eye worm) heat shock protein 75 0.0033 0.0024 0.0121
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 1
Echinococcus multilocularis GPCR, family 2 0.0064 0.0068 0.0068
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0077 0.0082
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0046 0.0927
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0073 0.1541
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0032 0.1116
Loa Loa (eye worm) oxidoreductase 0.0049 0.0046 0.023
Echinococcus multilocularis survival motor neuron protein 1 0.1405 0.2 0.2
Loa Loa (eye worm) hypothetical protein 0.0166 0.0214 0.1072
Leishmania major hypothetical protein, conserved 0.0056 0.0056 0.1153
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.012
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0077 0.0102
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.012
Onchocerca volvulus 0.0031 0.0021 0.019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0046 0.023
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0013 0.0194
Echinococcus multilocularis microtubule associated protein 2 0.6959 1 1
Plasmodium vivax heat shock protein 86, putative 0.005 0.0049 0.1555
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0073 0.1541
Leishmania major cathepsin L-like protease 0.005 0.0048 0.0967
Echinococcus multilocularis protein patched 0.0041 0.0035 0.0035
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0005 0.0023
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 0.7673
Loa Loa (eye worm) matrixin family protein 0.0243 0.0326 0.1632
Onchocerca volvulus Alhambra homolog 0.0119 0.0148 0.1469
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0032 0.0023 0.0023
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0021 0.0021
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0066 0.0071 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0226 0.0474
Brugia malayi Furin-like cysteine rich region family protein 0.0577 0.0808 0.4039
Mycobacterium tuberculosis Probable reductase 0.0323 0.0442 0.1012
Loa Loa (eye worm) hypothetical protein 0.0203 0.0268 0.134
Schistosoma mansoni zinc finger protein 0.0044 0.004 0.004
Echinococcus multilocularis dnaJ subfamily B 0.1287 0.183 0.183
Schistosoma mansoni heat shock protein 0.005 0.0049 0.0049
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0033 0.0024 0.0024
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.0201 0.0391
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0049 0.0046 0.0005
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0177 0.023 0.023
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0399 0.055 0.055
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0046 0.023
Schistosoma mansoni tyrosine kinase 0.0577 0.0808 0.0808
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 0.0451 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0002 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0034 0.0268
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.026 0.0351 0.0351
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0166 0.0214 0.0426
Trypanosoma brucei ISWI complex protein 0.0044 0.004 0.0787
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0035 0.028
Onchocerca volvulus 0.0102 0.0123 0.1222
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0049 0.0046 0.0046
Brugia malayi PHD-finger family protein 0.005 0.0047 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0013 0.0077
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0002 0.0002
Brugia malayi Sodium:solute symporter family protein 0.0032 0.0023 0.0113
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0047 0.0234
Echinococcus granulosus lysine specific demethylase 6a 0.0056 0.0056 0.0056
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0166 0.0214 0.0426
Plasmodium falciparum glutathione reductase 0.0142 0.018 0.7049
Brugia malayi Protein kinase domain containing protein 0.0186 0.0244 0.1218
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0002 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0072 0.0072
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Echinococcus multilocularis protein tyrosine kinase 0.0248 0.0333 0.0333
Mycobacterium ulcerans beta-lactamase 0.007 0.0077 0.0082
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0021 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0002 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0051 0.0049 0.1001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0002 0.0012
Echinococcus granulosus solute carrier family 5 0.0032 0.0023 0.0023
Echinococcus granulosus cysteine protease 0.0026 0.0013 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0166 0.0214 0.4868
Plasmodium vivax acyl-CoA synthetase, putative 0.0124 0.0154 0.5967
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0033 0.1148
Loa Loa (eye worm) matrixin family protein 0.0265 0.0358 0.179
Plasmodium vivax vivapain-1 0.0026 0.0013 0.0073
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0073 0.0073
Loa Loa (eye worm) MBCTL1 0.0051 0.005 0.0248
Schistosoma mansoni cpg binding protein 0.0101 0.0122 0.0122
Leishmania major cathepsin L-like protease 0.005 0.0048 0.0967
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0013 0.0188
Schistosoma mansoni microtubule-associated protein tau 0.6959 1 1
Leishmania major acetyl-CoA synthetase, putative 0.0049 0.0046 0.0927
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0106 0.0531
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0079 0.0685
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0046 0.0005
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0073 0.1541
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0002 0.0002
Giardia lamblia Kinase, PLK 0.0207 0.0274 0.6255
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0077 0.0668
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0033 0.0633
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0049 0.0046 0.096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0013 0.0188
Echinococcus multilocularis endoplasmin 0.0047 0.0044 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0035 0.0035
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0144 0.027
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0049 0.0046 0.0024
Loa Loa (eye worm) hypothetical protein 0.0249 0.0335 0.1677
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0035 0.0285
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0048 0.0048
Schistosoma mansoni tyrosine kinase 0.0306 0.0417 0.0417
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0005 0.0023
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Schistosoma mansoni cpg binding protein 0.009 0.0106 0.0106
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0103 0.0124 0.1232
Brugia malayi CXXC zinc finger family protein 0.009 0.0106 0.0531
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0106 0.0106
Brugia malayi CHD4 protein 0.0022 0.0008 0.0041
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0033 0.0261
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0232 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0033 0.0261
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0033 0.0655
Echinococcus multilocularis jumonji domain containing protein 0.0166 0.0215 0.0215
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0002 0.0012
Schistosoma mansoni bromodomain containing protein 0.0188 0.0247 0.0247
Leishmania major hypothetical protein, conserved 0.0024 0.0011 0.0149
Brugia malayi Heterochromatin protein 1 0.0071 0.0079 0.0394
Entamoeba histolytica hypothetical protein 0.0253 0.0341 0.7802
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0144 0.027
Loa Loa (eye worm) bromodomain containing protein 0.0051 0.005 0.0248
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0051 0.005 0.005
Onchocerca volvulus 0.0705 0.0991 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0035 0.0177
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0207 0.0274 0.0274
Onchocerca volvulus 0.005 0.0048 0.0459
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0047 0.0943
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0207 0.0274 0.1372
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0076 0.0076
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0033 0.0633
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.025 0.5487
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0077 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0099 0.0099
Trichomonas vaginalis esterase, putative 0.007 0.0077 0.0668
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.011 0.0134 0.0134
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.0201 0.0391
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0029 0.0222
Mycobacterium tuberculosis Conserved protein 0.007 0.0077 0.0102
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0051 0.0049 0.1589
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0013 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0139 0.0176 0.0878
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0047 0.0943
Schistosoma mansoni hypothetical protein 0.0064 0.0068 0.0068
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0051 0.0049 0.1589
Trypanosoma cruzi ISWI complex protein 0.0044 0.004 0.0787
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Brugia malayi hypothetical protein 0.0024 0.0011 0.0056
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0056
Brugia malayi protein kinase C3,putative 0.0082 0.0094 0.047
Loa Loa (eye worm) ctsf protein 0.005 0.0048 0.0239
Echinococcus granulosus histone lysine methyltransferase setb 0.014 0.0177 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0166 0.0214 0.0426
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0076 0.0076
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0134 0.0168 0.0842
Onchocerca volvulus 0.0249 0.0335 0.3367
Loa Loa (eye worm) glutaminase 2 0.0599 0.0839 0.4193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0002 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0048 0.1002
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Echinococcus multilocularis protein kinase c iota type 0.009 0.0105 0.0105
Plasmodium vivax vivapain-2 0.005 0.0048 0.1526
Trypanosoma cruzi major cysteine proteinase, putative 0.0149 0.0191 0.4175
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0049 0.0046 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.005 0.0048 0.1526
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 0.0378
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0173 0.0226 0.4955
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.005 0.0047 0.0237
Schistosoma mansoni peptidase Clp (S14 family) 0.0152 0.0195 0.0195
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0033 0.0261
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0045 0.0041 0.0386
Trichomonas vaginalis glucosylceramidase, putative 0.0534 0.0745 0.6833
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0077 0.0082
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0028 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.0274 0.0274
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0033 0.0164
Echinococcus granulosus polycomb protein SCMH1 0.0045 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0017 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0002 0.0012
Loa Loa (eye worm) TK/KIN16 protein kinase 0.015 0.0192 0.0961
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Brugia malayi Cathepsin L-like cysteine proteinase 0.0033 0.0024 0.012
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0013 0.0188
Toxoplasma gondii heat shock protein HSP90 0.005 0.0049 0.1783
Brugia malayi mbt repeat family protein 0.0045 0.0041 0.0203
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0323 0.0442 0.0994
Plasmodium falciparum thioredoxin reductase 0.0049 0.0047 0.1481
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0032 0.0023 0.0023
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0047 0.0389
Mycobacterium ulcerans glutaminase 0.0599 0.0839 0.1987
Loa Loa (eye worm) papain family cysteine protease containing protein 0.005 0.0048 0.0239
Leishmania major cathepsin L-like protease 0.005 0.0048 0.0967
Brugia malayi Bromodomain containing protein 0.0126 0.0158 0.0788
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0056 0.028
Brugia malayi Probable ClpP-like protease 0.0152 0.0195 0.0975
Brugia malayi Matrixin family protein 0.011 0.0134 0.067
Plasmodium falciparum acyl-CoA synthetase 0.0124 0.0154 0.5967
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0013 0.0194
Plasmodium falciparum endoplasmin, putative 0.0037 0.0029 0.0725
Schistosoma mansoni survival motor neuron protein 0.0287 0.0389 0.0389
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.0232 0.1161
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0043 0.0855
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0002 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0044 0.0364
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Echinococcus multilocularis 0.0178 0.0233 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0002 0.0012
Toxoplasma gondii FATC domain-containing protein 0.0027 0.0015 0.0434
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0035 0.0702
Brugia malayi Hemopexin family protein 0.0155 0.02 0.1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0002 0.0012
Echinococcus multilocularis isocitrate dehydrogenase 0.0051 0.0049 0.0049
Echinococcus granulosus cathepsin l1 0.0033 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.1207 0.1714 0.1714
Trypanosoma cruzi heat shock protein 90, putative 0.0043 0.0038 0.0749
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0077 0.0385
Onchocerca volvulus Cathepsin F homolog 0.005 0.0048 0.0459
Leishmania major trypanothione reductase 0.0142 0.018 0.3931
Schistosoma mansoni methyl-cpg binding protein mbd 0.0049 0.0047 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0033 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0134 0.0168 0.033
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0047 0.1711
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0068 0.0342
Toxoplasma gondii ABC1 family protein 0.007 0.0077 0.2941
Brugia malayi SET domain containing protein 0.0017 0 0.0002
Schistosoma mansoni chromobox protein 0.0071 0.0079 0.0079
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0013 0.0073
Echinococcus multilocularis cysteine protease 0.005 0.0048 0.0048
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.0328 0.1642
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0144 0.027
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0077 0.0668
Echinococcus multilocularis PHD finger protein rhinoceros 0.0119 0.0148 0.0148
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0002 0.0002
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.0232 0.0232
Echinococcus granulosus epidermal growth factor receptor 0.0311 0.0424 0.0424
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0035 0.0678
Loa Loa (eye worm) PHD-finger family protein 0.0119 0.0148 0.0738
Trichomonas vaginalis antibiotic synthetase, putative 0.0049 0.0046 0.0382
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0002 0.0002
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0011 0.0149
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0047 0.0943
Schistosoma mansoni hypothetical protein 0.0064 0.0068 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.0207 0.0274 0.604
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0072 0.0072
Trypanosoma brucei trypanothione reductase 0.0142 0.018 0.3931
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0943
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0009 0.0037
Trichomonas vaginalis endoplasmin, putative 0.0037 0.0029 0.0222
Trichomonas vaginalis glutaminase, putative 0.0599 0.0839 0.7698
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0152 0.0195 0.0195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Trypanosoma cruzi ISWI complex protein 0.0044 0.004 0.0787
Toxoplasma gondii hypothetical protein 0.0052 0.0051 0.1903
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0056 0.028
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0068 0.0342
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0076 0.0378
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0311 0.0424 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Plasmodium falciparum JmjC domain-containing protein, putative 0.0056 0.0056 0.1871
Plasmodium vivax hypothetical protein, conserved 0.007 0.0077 0.2746
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Schistosoma mansoni inositol transporter 0.0032 0.0023 0.0023
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.0328 0.1642
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0015 0.0076
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0048 0.0048
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Brugia malayi Bromodomain containing protein 0.0222 0.0296 0.148
Trypanosoma cruzi heat shock protein 85, putative 0.0043 0.0038 0.0749
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Loa Loa (eye worm) hypothetical protein 0.0484 0.0673 0.3364
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0011 0.0269
Schistosoma mansoni transcription factor LCR-F1 0.0253 0.0341 0.0341
Leishmania major cathepsin L-like protease 0.005 0.0048 0.0967
Loa Loa (eye worm) thioredoxin reductase 0.0142 0.018 0.0901
Toxoplasma gondii Hsp90 domain-containing protein 0.0191 0.0251 1
Brugia malayi jmjC domain containing protein 0.0056 0.0056 0.028
Echinococcus multilocularis chromobox protein 1 0.0071 0.0079 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Schistosoma mansoni heat shock protein 0.0033 0.0024 0.0024
Loa Loa (eye worm) matrix metalloproteinase 0.011 0.0134 0.067
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0048 0.1002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0044 0.004 0.1202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0027 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Echinococcus multilocularis insulin receptor 0.0186 0.0244 0.0244
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.025 0.5487
Trypanosoma brucei mitochondrial DNA polymerase beta 0.033 0.0451 1
Plasmodium vivax unspecified product 0.0026 0.0013 0.0073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0116 0.0579
Echinococcus granulosus geminin 0.1207 0.1714 0.1714
Echinococcus multilocularis chromobox protein 1 0.0071 0.0079 0.0079
Leishmania major cathepsin L-like protease 0.019 0.025 0.5487
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Loa Loa (eye worm) hypothetical protein 0.0045 0.0041 0.0203
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0049 0.0049
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0033 0.0024 0.0454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Plasmodium vivax SET domain protein, putative 0.0091 0.0106 0.3974
Schistosoma mansoni endoplasmin 0.005 0.0049 0.0049
Echinococcus multilocularis cathepsin L 0.0026 0.0013 0.0013
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Trypanosoma brucei heat shock protein 90, putative 0.005 0.0049 0.0983
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0049 0.0046 0.023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Leishmania major cysteine peptidase A (CPA) 0.005 0.0048 0.0967
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Leishmania major cathepsin L-like protease 0.019 0.025 0.5487
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0077 0.0668
Echinococcus multilocularis geminin 0.1207 0.1714 0.1714
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.0201 0.041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0047 0.1481
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Schistosoma mansoni alpha glucosidase 0.0039 0.0033 0.0033
Loa Loa (eye worm) RNA binding protein 0.0069 0.0076 0.0378
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0073 0.0073
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Schistosoma mansoni hypothetical protein 0.0044 0.004 0.004
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0035 0.0035
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0047 0.0943
Echinococcus granulosus chromobox protein 1 0.0071 0.0079 0.0079
Echinococcus granulosus JmjC domain containing protein 4 0.0056 0.0056 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0005 0.0001
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0174 0.0174
Echinococcus granulosus serine protein kinase ATM 0.0027 0.0015 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0033 0.0261
Schistosoma mansoni endoplasmin 0.005 0.0049 0.0049
Schistosoma mansoni jumonji domain containing protein 0.0056 0.0056 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0046 0.0005
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 0.0378
Schistosoma mansoni tyrosine kinase 0.0186 0.0244 0.0244
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0043 0.0038 0.0038
Plasmodium vivax thioredoxin reductase, putative 0.0142 0.018 0.7049
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0038 0.0308
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0047 0.0044 0.0019
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Schistosoma mansoni methyl-cpg binding protein mbd 0.0049 0.0047 0.0047
Echinococcus granulosus GPCR family 2 0.0064 0.0068 0.0068
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0002 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0013 0.0065
Loa Loa (eye worm) hypothetical protein 0.011 0.0134 0.067
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0048 0.0048
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0048 0.0048
Toxoplasma gondii histone lysine methyltransferase SET1 0.0181 0.0237 0.9449
Leishmania major cathepsin L-like protease 0.005 0.0048 0.0967
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0013 0.0188
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0293 0.0399 0.1994
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0038 0.0308
Trypanosoma cruzi Heat shock protein 83, putative 0.005 0.0049 0.0983
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0052 0.0051 0.1679
Plasmodium falciparum heat shock protein 90 0.005 0.0049 0.1555
Mycobacterium ulcerans hypothetical protein 0.0174 0.0226 0.0456
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0002 0.0012
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.0033
Echinococcus multilocularis expressed conserved protein 0.009 0.0106 0.0106
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.025 0.5487
Schistosoma mansoni phosphatidylserine receptor 0.0056 0.0056 0.0056
Loa Loa (eye worm) jmjC domain-containing protein 0.0246 0.033 0.1652
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0033 0.0164
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0068 0.0068
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0203 0.0268 0.134
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0056 0.0056 0.1153
Entamoeba histolytica heat shock protein 90, putative 0.005 0.0049 0.1018
Echinococcus multilocularis cpg binding protein 0.0101 0.0122 0.0122
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0068 0.0068
Onchocerca volvulus 0.0033 0.0024 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0013 0.0013
Echinococcus granulosus cathepsin L 0.0026 0.0013 0.0013
Plasmodium vivax vivapain-3 0.0026 0.0013 0.0073
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0049 0.1001
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Schistosoma mansoni jumonji/arid domain-containing protein 0.0219 0.0292 0.0292
Schistosoma mansoni hypothetical protein 0.0064 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0035 0.028
Onchocerca volvulus 0.005 0.0048 0.0459
Loa Loa (eye worm) hypothetical protein 0.0049 0.0046 0.023
Echinococcus granulosus SAM and MBT domain containing protein 0.0045 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.006 0.0062 0.0062
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0048 0.0399
Brugia malayi steroid hormone receptor 0.0018 0.0002 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0076 0.0076
Echinococcus granulosus zinc finger protein 0.0062 0.0065 0.0065
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0152 0.0195 0.0378
Giardia lamblia Heat shock protein HSP 90-alpha 0.0043 0.0038 0.0775
Schistosoma mansoni bromodomain containing protein 0.0018 0.0001 0.0001
Mycobacterium ulcerans AcrR family transcriptional regulator 0.2823 0.4042 1
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0077 0.0668
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0013 0.0013
Echinococcus multilocularis high affinity choline transporter 1 0.0293 0.0399 0.0399
Trypanosoma cruzi heat shock protein 90, putative 0.005 0.0049 0.0983
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0152 0.0195 0.0195
Onchocerca volvulus 0.005 0.0048 0.0459
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Treponema pallidum fructose-bisphosphate aldolase 0.0319 0.0436 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0195 0.0257 0.0257
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0033 0.0024 0.0024
Schistosoma mansoni tyrosine kinase 0.0248 0.0333 0.0333
Brugia malayi Endoplasmin precursor 0.005 0.0049 0.0243
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0124 0.0154 0.0294
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0048 0.0399
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0056 0.0056 0.209
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0027 0.0015 0.0239
Loa Loa (eye worm) hypothetical protein 0.0166 0.0214 0.1072
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0032 0.0023 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0049 0.0046 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Mycobacterium leprae PROBABLE HYDROLASE 0.0134 0.0168 0.0311
Entamoeba histolytica hypothetical protein 0.0253 0.0341 0.7802
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.0033
Schistosoma mansoni alpha-glucosidase 0.0153 0.0197 0.0197
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0186 0.0244 0.0244
Echinococcus granulosus peptidase Clp S14 family 0.01 0.012 0.012
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0047 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0013 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0035 0.0678
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0323 0.0442 0.1012
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0046 0.023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0323 0.0442 0.1012
Onchocerca volvulus 0.011 0.0134 0.133
Brugia malayi Matrixin family protein 0.011 0.0134 0.067
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.0192 0.0961
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Mycobacterium tuberculosis Conserved protein 0.007 0.0077 0.0102
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0178 0.0232 0.0232
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0274 0.249
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0116 0.0116
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0073 0.1596
Brugia malayi nuclear hormone receptor 0.0018 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0119 0.0148 0.0738
Trichomonas vaginalis antibiotic synthetase, putative 0.0049 0.0046 0.0382
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0166 0.0214 0.0426
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0049 0.0046 0.0024
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0046 0.0927
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0077 0.0077
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0006 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Trichomonas vaginalis set domain proteins, putative 0.0705 0.0991 0.9109
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0195 0.7735
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0117 0.0117
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0943
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0047 0.0943
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0068 0.0342
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Brugia malayi serine/threonine-protein kinase plk-2 0.0207 0.0274 0.1372
Brugia malayi Cathepsin L-like precursor 0.005 0.0048 0.0239
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0056 0.0056 0.1153
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0035 0.0035
Toxoplasma gondii thioredoxin reductase 0.0142 0.018 0.7128
Trypanosoma cruzi heat shock protein 85, putative 0.005 0.0049 0.0983
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0181 0.0181
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0056 0.0056 0.0056
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0072 0.0069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0068 0.0342
Trichomonas vaginalis heat shock protein, putative 0.005 0.0049 0.0405
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0002 0.0012
Onchocerca volvulus Cathepsin L homolog 0.005 0.0048 0.0459
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0047 0.1481
Echinococcus granulosus peregrin 0.0126 0.0158 0.0158
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0013 0.0013
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0049 0.0046 0.0005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0044 0.004 0.0787
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0051 0.0049 0.0049
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0273 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.007 0.0077 0.0385
Plasmodium vivax heat shock protein, putative 0.0191 0.0251 1
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0124 0.11
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0072 0.0069
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0115 0.0573
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Brugia malayi latrophilin 2 splice variant baaae 0.0139 0.0176 0.0878
Giardia lamblia PHD finger protein 15 0.0119 0.0148 0.3318
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0077 0.0385
Leishmania major heat shock protein 83-1 0.005 0.0049 0.0983
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0046 0.0927
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.007 0.0077 0.0077
Brugia malayi CHE-14 protein 0.0041 0.0035 0.0177
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0073 0.1541
Schistosoma mansoni inositol transporter 0.0032 0.0023 0.0023
Brugia malayi ecdysteroid receptor 0.0018 0.0002 0.0012
Brugia malayi mbt repeat family protein 0.0045 0.0041 0.0203
Brugia malayi AMP-binding enzyme family protein 0.0166 0.0214 0.1072
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0018 0.0125
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0022 0.0164
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0012
Echinococcus granulosus protein tyrosine kinase 0.0248 0.0333 0.0333
Loa Loa (eye worm) runx1 0.0061 0.0063 0.0317
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0049 0.0046 0.023
Schistosoma mansoni hypothetical protein 0.004 0.0033 0.0033
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0116 0.0116
Schistosoma mansoni atypical protein kinase C 0.0095 0.0113 0.0113
Brugia malayi Cathepsin L-like precursor 0.0033 0.0024 0.012
Schistosoma mansoni hypothetical protein 0.0119 0.0148 0.0148
Echinococcus multilocularis epidermal growth factor receptor 0.0577 0.0808 0.0808
Brugia malayi Pre-SET motif family protein 0.062 0.0868 0.4342
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0073 0.0367
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0166 0.0214 0.0445
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0073 0.0073
Schistosoma mansoni cellular tumor antigen P53 0.0249 0.0335 0.0335
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0013 0.0013
Brugia malayi Matrixin family protein 0.0265 0.0358 0.179
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0047 0.1711
Echinococcus multilocularis cysteine protease 0.005 0.0048 0.0048
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0002 0.0002
Brugia malayi Thioredoxin reductase 0.0142 0.018 0.0901
Loa Loa (eye worm) hypothetical protein 0.0111 0.0136 0.068
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0104 0.0126 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0009 0.0037
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0049 0.0046 0.0005
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0051 0.0049 0.0049
Schistosoma mansoni patched 1 0.0041 0.0035 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0116 0.0116
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0035 0.0035
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0049 0.0046 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0166 0.0214 0.1072
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.0232 0.1161
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0248
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0033 0.0261
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0038 0.0308
Echinococcus multilocularis JmjC domain containing protein 4 0.0056 0.0056 0.0056
Echinococcus granulosus heat shock protein 90 0.005 0.0049 0.0049
Schistosoma mansoni zinc finger protein 0.0062 0.0065 0.0065
Echinococcus multilocularis peptidase Clp (S14 family) 0.01 0.012 0.012
Brugia malayi Matrixin family protein 0.011 0.0134 0.067
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.0177 0.0177
Echinococcus granulosus high affinity choline transporter 1 0.0293 0.0399 0.0399
Toxoplasma gondii hypothetical protein 0.0053 0.0053 0.195
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0534 0.0745 0.6833
Onchocerca volvulus 0.005 0.0048 0.0459
Schistosoma mansoni hypothetical protein 0.1287 0.183 0.183
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0195 0.3855
Onchocerca volvulus 0.0287 0.0389 0.3907
Schistosoma mansoni hypothetical protein 0.1207 0.1714 0.1714
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0002 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0166 0.0214 0.1072
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0104 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Schistosoma mansoni hypothetical protein 0.0139 0.0176 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0077 0.0102
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Trypanosoma brucei heat shock protein, putative 0.005 0.0049 0.0983
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0049 0.0046 0.0005
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.01 0.012 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Leishmania major hypothetical protein, conserved 0.007 0.0077 0.1622
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 0.0451 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0142 0.018 0.0359
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0287 0.0389 0.0389
Loa Loa (eye worm) glutaminase 0.0599 0.0839 0.4193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0048 0.0399
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0049 0.1001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0253 0.0341 0.0341
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0181 0.0181
Plasmodium vivax acetyl-CoA synthetase, putative 0.0049 0.0046 0.1451
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.014 0.0177 0.0888
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0166 0.0214 0.0426
Echinococcus multilocularis polycomb protein SCMH1 0.0045 0.0041 0.0041
Echinococcus granulosus histone acetyltransferase MYST2 0.0051 0.005 0.005
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0011 0.0149
Mycobacterium ulcerans lipase LipD 0.007 0.0077 0.0082
Entamoeba histolytica cysteine protease, putative 0.0026 0.0013 0.0194
Echinococcus multilocularis tumor protein p63 0.1704 0.2431 0.2431
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.0005 0.0005
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0045 0.0041 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.0436 0.398
Schistosoma mansoni tyrosine kinase 0.0311 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0129 0.0161 0.0806
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0207 0.0274 0.0274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0048 0.0399
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0032 0.0023 0.0732
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0002 0.0012
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0047 0.0977
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.025 0.5487
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0057 0.1183
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0205 0.0271 0.1354
Onchocerca volvulus 0.007 0.0077 0.0755
Loa Loa (eye worm) hypothetical protein 0.0124 0.0154 0.0771
Toxoplasma gondii heat shock protein 90, putative 0.005 0.0049 0.1783
Leishmania major 4-coumarate:coa ligase-like protein 0.0166 0.0214 0.47
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0047 0.0389
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0021 0.0021
Echinococcus granulosus tumor protein p63 0.1704 0.2431 0.2431
Onchocerca volvulus 0.005 0.0048 0.0459
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0033 0.0261
Onchocerca volvulus 0.005 0.0048 0.0459
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0013 0.0013
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0039 0.0032 0.1116
Plasmodium vivax hypothetical protein, conserved 0.0044 0.004 0.1202
Mycobacterium ulcerans acetyl-CoA synthetase 0.0049 0.0046 0.0005
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0166 0.0214 0.0445
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0116 0.0579
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0046 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0116 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Trypanosoma brucei polo-like protein kinase 0.0207 0.0274 0.604
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0047 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0142 0.018 0.3931
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0024 0.0451
Treponema pallidum NADH oxidase 0.0049 0.0047 0.0068
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0035 0.0678
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0155 0.02 0.1998
Trichomonas vaginalis glucosylceramidase, putative 0.0772 0.1088 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0043 0.0855
Trichomonas vaginalis glucosylceramidase, putative 0.0506 0.0706 0.647
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0035 0.0035
Echinococcus multilocularis phd:f box containing protein 0.0056 0.0056 0.0056
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0052 0.0051 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0022 0.0164
Leishmania major cathepsin L-like protease 0.019 0.025 0.5487
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0323 0.0442 0.1012

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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