Detailed information for compound 665605

Basic information

Technical information
  • TDR Targets ID: 665605
  • Name: ZINC01146264
  • MW: 400.879 | Formula: C20H17ClN2O3S
  • H donors: 2 H acceptors: 3 LogP: 4.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)NS(=O)(=O)c1ccc(cc1)NC(=O)c1ccccc1Cl
  • InChi: 1S/C20H17ClN2O3S/c1-14-5-4-6-16(13-14)23-27(25,26)17-11-9-15(10-12-17)22-20(24)18-7-2-3-8-19(18)21/h2-13,23H,1H3,(H,22,24)
  • InChiKey: GFXMIINGJSJXTH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0027 0.0157 0.0157
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0176 0.0176
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0014 0.0016 0.0094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis GPCR, family 2 0.0013 0.0007 0.0007
Echinococcus granulosus neuropeptide receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0503 0.0503
Echinococcus granulosus fibropellin Ia 0.0018 0.0061 0.0061
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0175 0.1661 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Entamoeba histolytica hypothetical protein, conserved 0.0308 0.3012 1
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0107 0.0971 0.5845
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0014 0.0016 0.0094
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Mycobacterium tuberculosis Probable oxidoreductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) hypothetical protein 0.0066 0.0554 0.1838
Schistosoma mansoni opsin-like receptor 0.0029 0.0176 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0014 0.0014
Echinococcus granulosus lipoxygenase domain containing protein 0.0177 0.1678 0.1678
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0176 0.0695
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0056 0.0443 0.2642
Schistosoma mansoni biogenic amine receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0497 0.4937 1
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis retinol dehydrogenase 13 0.0014 0.0016 0.0016
Mycobacterium tuberculosis Probable dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0014 0.0053
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0176 0.0176
Echinococcus granulosus notch 0.0018 0.0061 0.0061
Onchocerca volvulus 0.0014 0.0016 0.0093
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0014 0.0016 0.0094
Brugia malayi hypothetical protein 0.002 0.0084 0.0333
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0014 0.0016 0.0094
Schistosoma mansoni survival motor neuron protein 0.0032 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) hypothetical protein 0.0051 0.0392 0.1303
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0014 0.0016 0.0094
Brugia malayi Serotonin receptor 0.0029 0.0176 0.0695
Mycobacterium tuberculosis Possible oxidoreductase 0.0014 0.0016 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus multilocularis cpg binding protein 0.0031 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0013 0.0014 0.0081
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Schistosoma mansoni neuropeptide receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0176 0.0585
Brugia malayi Cadherin domain containing protein 0.0018 0.0061 0.0239
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0051 0.0392 0.0392
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0014 0.0016 0.0094
Plasmodium vivax steroid dehydrogenase, putative 0.0014 0.0016 0.0093
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0014 0.0016 0.0016
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0061 0.0061
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Schistosoma mansoni rab6-interacting 0.0177 0.1678 0.1678
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0014 0.0053
Loa Loa (eye worm) dehydrogenase 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Schistosoma mansoni sphingosine kinase A B 0.0308 0.3012 0.3012
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0176 0.0176
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0176 0.0176
Schistosoma mansoni hypothetical protein 0.0029 0.0176 0.0176
Echinococcus multilocularis protein jagged 1 0.0018 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Brugia malayi G-protein coupled receptor 0.0029 0.0176 0.0695
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0176 0.0176
Leishmania major pteridine reductase 1 0.0014 0.0016 0.0094
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0014 0.0016 0.0032
Brugia malayi G protein-coupled receptor 0.0029 0.0176 0.0695
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0176 0.1051
Schistosoma mansoni cpg binding protein 0.0031 0.0189 0.0189
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0084 0.0508
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0176 0.1051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0014 0.0014
Onchocerca volvulus 0.0029 0.0176 0.1051
Onchocerca volvulus 0.0013 0.0014 0.0081
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0014 0.0016 0.0094
Mycobacterium tuberculosis Probable oxidoreductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0107 0.0971 0.3223
Echinococcus granulosus fmrfamide receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0162 0.1523 0.6009
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0014 0.0014
Loa Loa (eye worm) vesicle-fusing ATPase 0.0066 0.0554 0.1838
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0014 0.0016 0.0032
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.1661 0.9899
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0176 0.0176
Trypanosoma brucei short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0016 0.0052
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0176 0.0176
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0014 0.0014
Onchocerca volvulus 0.0177 0.1678 1
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) doublecortin family protein 0.0177 0.1678 0.557
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0014 0.0016 0.0016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.0408 0.0408
Echinococcus granulosus WW domain containing oxidoreductase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Echinococcus multilocularis geminin 0.0136 0.1266 0.1266
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0175 0.1661 1
Echinococcus granulosus survival motor neuron protein 1 0.0158 0.1488 0.1488
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0176 0.0176
Echinococcus granulosus microtubule associated protein 2 0.0696 0.6953 0.6953
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0014 0.0014
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Onchocerca volvulus Neurogenic locus notch homolog 0.0018 0.0061 0.0361
Leishmania major dihydroorotate dehydrogenase 0.0175 0.1661 1
Onchocerca volvulus 0.0014 0.0016 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis somatostatin receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0162 0.1523 0.5057
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0084 0.0508
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Onchocerca volvulus 0.0032 0.0206 0.123
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0068 0.0574 0.0574
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0014 0.0014
Brugia malayi hypothetical protein 0.0056 0.0443 0.1749
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0014 0.0016 0.0094
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0176 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Schistosoma mansoni amine GPCR 0.0029 0.0176 0.0176
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0176 0.0176
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0107 0.0971 0.0971
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0014 0.0016 0.0032
Brugia malayi ORL1-like opioid receptor 0.0029 0.0176 0.0695
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Brugia malayi hypothetical protein 0.0177 0.1678 0.6619
Mycobacterium ulcerans ATPase 0.0068 0.0567 0.1149
Schistosoma mansoni histamine h1 receptor 0.0029 0.0176 0.0176
Brugia malayi Delta serrate ligand family protein 0.0018 0.0061 0.0239
Echinococcus multilocularis fat cadherin tumor suppressor 0.0018 0.0061 0.0061
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0176 0.0176
Onchocerca volvulus Peroxidasin homolog 0.0056 0.0443 0.2642
Echinococcus multilocularis lipoxygenase domain containing protein 0.0177 0.1678 0.1678
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Brugia malayi valosin containing protein 0.0066 0.0554 0.2184
Brugia malayi nuclear receptor NHR-88 0.0013 0.0014 0.0053
Loa Loa (eye worm) notch protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) VCP protein 0.0047 0.0354 0.1176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus granulosus hypothetical protein 0.0029 0.0176 0.0176
Mycobacterium tuberculosis Conserved protein 0.0308 0.3012 0.61
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0014 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0176 0.0176
Schistosoma mansoni aldehyde dehydrogenase 0.008 0.0693 0.0693
Toxoplasma gondii oxidoreductase, putative 0.0014 0.0016 0.0094
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0094
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0014 0.0016 0.0094
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0122 0.1119 0.3716
Brugia malayi Dopamine receptor protein 2 0.0029 0.0176 0.0695
Onchocerca volvulus 0.0014 0.0016 0.0093
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0176 0.0176
Schistosoma mansoni hypothetical protein 0.0029 0.0176 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni protein kinase 0.0052 0.0408 0.0408
Loa Loa (eye worm) animal heme peroxidase 0.0056 0.0443 0.1472
Brugia malayi G-protein coupled receptor 0.0029 0.0176 0.0695
Brugia malayi follicle stimulating hormone receptor 0.0261 0.2535 1
Brugia malayi ecdysteroid receptor 0.0013 0.0014 0.0053
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0047 0.0354 0.0354
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Schistosoma mansoni carbonyl reductase 0.0014 0.0016 0.0016
Schistosoma mansoni carbonyl reductase 0.0014 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0013 0.0007 0.0024
Brugia malayi hypothetical protein 0.0177 0.1678 0.6619
Loa Loa (eye worm) hypothetical protein 0.0177 0.1678 0.557
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0107 0.0971 0.5786
Brugia malayi Retinol dehydrogenase 12 0.0014 0.0016 0.0062
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0162 0.1523 0.5057
Onchocerca volvulus 0.0014 0.0016 0.0093
Mycobacterium ulcerans short-chain dehydrogenase 0.0014 0.0016 0.0032
Onchocerca volvulus 0.0056 0.0443 0.2642
Echinococcus multilocularis carbonyl reductase 1 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0693 0.1403
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Leishmania major hypothetical protein, conserved 0.0014 0.0016 0.0094
Loa Loa (eye worm) animal heme peroxidase 0.0056 0.0443 0.1472
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0014 0.0016 0.0052
Schistosoma mansoni coup transcription factor 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Plasmodium falciparum steroid dehydrogenase, putative 0.0014 0.0016 0.0093
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Onchocerca volvulus Putative cubilin 0.0018 0.0061 0.0361
Mycobacterium ulcerans hypothetical protein 0.0308 0.3012 0.61
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0176 0.0695
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Onchocerca volvulus 0.0029 0.0176 0.1051
Brugia malayi Dopamine receptor 0.0029 0.0176 0.0695
Onchocerca volvulus 0.0029 0.0172 0.1028
Onchocerca volvulus 0.0029 0.0176 0.1051
Brugia malayi nuclear hormone receptor 0.0013 0.0014 0.0053
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0014 0.0016 0.0032
Brugia malayi Protein kinase domain containing protein 0.0162 0.1523 0.6009
Brugia malayi CXXC zinc finger family protein 0.0029 0.0172 0.068
Echinococcus granulosus sex peptide receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0014 0.0016 0.0032
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.5574
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0014 0.0016 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Echinococcus multilocularis neural cadherin 0.0018 0.0061 0.0061
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.008 0.0693 0.1403
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0162 0.1523 0.1523
Onchocerca volvulus 0.0029 0.0176 0.1051
Echinococcus granulosus somatostatin receptor 0.0029 0.0176 0.0176
Schistosoma mansoni neuropeptide receptor 0.0029 0.0176 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0014 0.0045
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0176 0.1051
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0014 0.0016 0.0094
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0176 0.1051
Mycobacterium ulcerans oxidoreductase 0.0014 0.0016 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0176 0.0176
Brugia malayi Cadherin domain containing protein 0.0018 0.0061 0.0239
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0014 0.0016 0.0094
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0014 0.0016 0.0032
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0014 0.0016 0.0016
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0013 0.0007 0.0007
Loa Loa (eye worm) animal heme peroxidase 0.0056 0.0443 0.1472
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0162 0.1523 0.1523
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0176 0.0176
Echinococcus granulosus hypothetical protein 0.0014 0.0016 0.0016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0014 0.0016 0.0016
Schistosoma mansoni cpg binding protein 0.0031 0.0189 0.0189
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0408 0.0408
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0014 0.0014
Schistosoma mansoni rab6-interacting 0.0177 0.1678 0.1678
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Plasmodium falciparum LCCL domain-containing protein 0.0177 0.1678 1
Echinococcus granulosus geminin 0.0136 0.1266 0.1266
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0175 0.1661 1
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Schistosoma mansoni slit 0.0018 0.0061 0.0061
Echinococcus granulosus g protein coupled receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.008 0.0693 0.0693
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Schistosoma mansoni polycystin 1-related 0.0177 0.1678 0.1678
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0014 0.0016 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0176 0.0585
Brugia malayi putative neuropeptide receptor 0.0029 0.0176 0.0695
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Echinococcus granulosus hypothetical protein 0.0014 0.0016 0.0016
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0176 0.0695
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0014 0.0016 0.0062
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain type oxidoreductase 0.0014 0.0016 0.0032
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0113 0.103 0.103
Echinococcus multilocularis protein jagged 1 0.0018 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.002 0.0084 0.028
Schistosoma mansoni vam6/vps39 related 0.0051 0.0392 0.0392
Schistosoma mansoni cpg binding protein 0.0029 0.0172 0.0172
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0014 0.0016 0.0152
Echinococcus granulosus protein jagged 2 0.0018 0.0061 0.0061
Toxoplasma gondii carbonyl reductase 1, putative 0.0014 0.0016 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Mycobacterium ulcerans ketoacyl reductase 0.0014 0.0016 0.0032
Brugia malayi Dopamine receptor protein 1 0.0029 0.0176 0.0695
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Leishmania major hypothetical protein, conserved 0.0014 0.0016 0.0094
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis neurogenic locus notch protein 4 0.0018 0.0061 0.0061
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0061 0.0061
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0014 0.0016 0.0016
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Brugia malayi Blistered cuticle protein 3 0.0056 0.0443 0.1749
Echinococcus granulosus Vam6:Vps39 protein 0.0051 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus dnaJ subfamily B 0.0412 0.4072 0.4072
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0172 0.0572
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0016 0.0093
Schistosoma mansoni biogenic amine receptor 0.0029 0.0176 0.0176
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Onchocerca volvulus 0.0014 0.0016 0.0093
Mycobacterium ulcerans dehydrogenase/reductase 0.0014 0.0016 0.0032
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.008 0.0693 0.4171
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0176 0.0176
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0013 0.0007 0.0028
Schistosoma mansoni aldehyde dehydrogenase 0.008 0.0693 0.0693
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0014 0.0014
Toxoplasma gondii EGF family domain-containing protein 0.0018 0.0061 0.0365
Brugia malayi latrophilin 2 splice variant baaae 0.0027 0.0157 0.062
Onchocerca volvulus 0.0029 0.0176 0.1051
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Onchocerca volvulus 0.0029 0.0176 0.1051
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0051 0.0392 0.2364
Echinococcus multilocularis RUN 0.0177 0.1678 0.1678
Leishmania major hypothetical protein, conserved 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) Notch2 0.0018 0.0061 0.0201
Brugia malayi steroid hormone receptor 0.0013 0.0014 0.0053
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0176 0.0695
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0014 0.0053
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0176 0.0176
Echinococcus granulosus oxidoreductase 0.0014 0.0016 0.0016
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0176 0.0176
Echinococcus granulosus neurogenic locus notch protein 4 0.0018 0.0061 0.0061
Leishmania major short chain dehydrogenase, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Mycobacterium tuberculosis Probable oxidoreductase 0.0014 0.0016 0.0032
Brugia malayi hypothetical protein 0.0014 0.0016 0.0062
Brugia malayi neuropeptide F receptor 0.0029 0.0176 0.0695
Brugia malayi AKH receptor 0.0029 0.0176 0.0695
Schistosoma mansoni sphingoid long chain base kinase 0.0308 0.3012 0.3012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0014 0.0016 0.0052
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0061 0.0061
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0084 0.0508
Brugia malayi Doublecortin family protein 0.0177 0.1678 0.6619
Onchocerca volvulus 0.0014 0.0016 0.0093
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium tuberculosis Probable oxidoreductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0995 1 1
Onchocerca volvulus 0.0029 0.0176 0.1051
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0047 0.0354 0.0354
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus multilocularis carbonyl reductase 1 0.0014 0.0016 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Brugia malayi Serotonin receptor 0.0029 0.0176 0.0695
Onchocerca volvulus Protein ultraspiracle homolog 0.0013 0.0014 0.0081
Echinococcus multilocularis retinol dehydrogenase 11 0.0014 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0014 0.0053
Toxoplasma gondii cell division protein CDC48AP 0.0068 0.0567 0.3417
Echinococcus granulosus serotonin receptor 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0176 0.0176
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0176 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Echinococcus granulosus carbonyl reductase 1 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Schistosoma mansoni hypothetical protein 0.0032 0.0206 0.0206
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0014 0.0014
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0016 0.0052
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0068 0.0574 0.0574
Echinococcus granulosus protein jagged 1 0.0018 0.0061 0.0061
Onchocerca volvulus Bile acid receptor homolog 0.0013 0.0014 0.0081
Brugia malayi GCC2 and GCC3 family protein 0.0018 0.0061 0.0239
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0183 0.1735 0.1735
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0052 0.0408 0.0408
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0052 0.0408 0.0408
Entamoeba histolytica short chain dehydrogenase family protein 0.0014 0.0016 0.0052
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.5574
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0014 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0175 0.1661 1
Echinococcus multilocularis slit 2 protein 0.0018 0.0061 0.0061
Mycobacterium ulcerans carveol-like dehydrogenase 0.0014 0.0016 0.0032
Schistosoma mansoni microtubule-associated protein tau 0.0696 0.6953 0.6953
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0014 0.0045
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0014 0.0053
Onchocerca volvulus Peroxidase homolog 0.0056 0.0443 0.2642
Schistosoma mansoni adenoreceptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Giardia lamblia AAA family ATPase 0.0068 0.0567 1
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0183 0.1735 0.1735
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Brugia malayi Animal haem peroxidase family protein 0.0056 0.0443 0.1749
Entamoeba histolytica hypothetical protein 0.0014 0.0016 0.0052
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0094
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0014 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0013 0.0007 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Trichomonas vaginalis proteasome-activating nucleotidase, putative 0.0027 0.015 0.1459
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0094
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0176 0.0176
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0014 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Brugia malayi sulfakinin receptor protein 0.0029 0.0176 0.0695
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0014 0.0016 0.0094
Mycobacterium ulcerans dehydrogenase 0.0014 0.0016 0.0032
Mycobacterium tuberculosis Probable oxidoreductase 0.0497 0.4937 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0068 0.0574 0.0574
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi short chain dehydrogenase, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis serotonin receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans oxidoreductase 0.0014 0.0016 0.0032
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0061 0.0239
Schistosoma mansoni hypothetical protein 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.004 0.0286 0.0951
Schistosoma mansoni peroxidasin 0.0056 0.0443 0.0443
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0176 0.0176
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0014 0.0016 0.0016
Brugia malayi Dehydrogenases, short chain protein 2 0.0014 0.0016 0.0062
Schistosoma mansoni rap gtpase-activating protein 0.0051 0.0392 0.0392
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0014 0.0053
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0176 0.0695
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Onchocerca volvulus 0.0029 0.0176 0.1051
Onchocerca volvulus Peroxidase homolog 0.0056 0.0443 0.2642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0176 0.0176
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0176 0.0176
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0176 0.0176
Schistosoma mansoni carbonyl reductase 0.0014 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0014 0.0045
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0176 0.1051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0014 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0176 0.1051
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0014 0.0016 0.0094
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0176 0.0176
Schistosoma mansoni lipoxygenase 0.0995 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0176 0.0176
Brugia malayi larval opioid receptor 0.0029 0.0176 0.0695
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Onchocerca volvulus 0.0018 0.0061 0.0361
Schistosoma mansoni dihydroorotate dehydrogenase 0.0175 0.1661 0.1661
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Onchocerca volvulus Peroxidasin homolog 0.0056 0.0443 0.2642
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0014 0.0016 0.0094
Echinococcus multilocularis carbonyl reductase 1 0.0014 0.0016 0.0016
Brugia malayi Dehydrogenases, short chain protein 30 0.0014 0.0016 0.0062
Trypanosoma cruzi Valosin-containing protein, putative 0.0107 0.0971 0.5845
Onchocerca volvulus 0.0029 0.0176 0.1051
Schistosoma mansoni septate junction protein 0.0018 0.0061 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0016 0.0093
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0014 0.0014
Echinococcus granulosus protein jagged 1 0.0018 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0051 0.0392 0.1303
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0158 0.1488 0.494
Brugia malayi hypothetical protein 0.0051 0.0392 0.1548
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.0408 0.0408
Schistosoma mansoni protein kinase 0.0173 0.1634 0.1634
Echinococcus multilocularis retinol dehydrogenase 11 0.0014 0.0016 0.0016
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0018 0.0061 0.0061
Echinococcus granulosus retinol dehydrogenase 11 0.0014 0.0016 0.0016
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0176 0.0176
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0176 0.0176
Echinococcus granulosus carbonyl reductase 1 0.0014 0.0016 0.0016
Echinococcus granulosus allatostatin A receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0014 0.0016 0.0062
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.004 0.0286 0.1129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Toxoplasma gondii aldehyde dehydrogenase 0.008 0.0693 0.4171
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0176 0.0176
Trypanosoma brucei short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0014 0.0016 0.0094
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0176 0.0695
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0029 0.0176 0.0176
Echinococcus multilocularis 0.0122 0.1119 0.1119
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0308 0.3012 1
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Leishmania major short chain dehydrogenase, putative 0.0014 0.0016 0.0094
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0051 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0014 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0176 0.0176
Echinococcus granulosus orexin receptor type 2 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.5574
Toxoplasma gondii transitional endoplasmic reticulum ATPase, putative 0.0068 0.0567 0.3417
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0014 0.0016 0.0032
Onchocerca volvulus Dual oxidase homolog 0.0056 0.0443 0.2642
Onchocerca volvulus 0.0014 0.0016 0.0093
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0061 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0176 0.0585
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Echinococcus multilocularis steroid dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0412 0.4072 0.4072
Echinococcus granulosus sphingosine kinase 1 0.0308 0.3012 0.3012
Echinococcus granulosus carbonyl reductase 1 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Brugia malayi notch-like transmembrane receptor 0.0018 0.0061 0.0239
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Echinococcus multilocularis steroid dehydrogenase 0.0014 0.0016 0.0016
Brugia malayi neuropeptide F receptor 0.0029 0.0176 0.0695
Onchocerca volvulus 0.0029 0.0176 0.1051
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0436 0.2624
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.0113 0.103 0.103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0014 0.0014
Echinococcus granulosus delta-like protein 1 0.0018 0.0061 0.0061
Echinococcus multilocularis peroxidasin 0.0056 0.0443 0.0443
Onchocerca volvulus 0.0018 0.0061 0.0361
Echinococcus multilocularis sphingosine kinase 1 0.0308 0.3012 0.3012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0176 0.0585
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0176 0.0176
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0016 0.0016
Onchocerca volvulus 0.0056 0.0443 0.2642
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0084 0.0503
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0176 0.0585
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Entamoeba histolytica cdc48-like protein, putative 0.0107 0.0971 0.3223
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Leishmania major hypothetical protein, conserved 0.0014 0.0016 0.0094
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0014 0.0016 0.0032
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0084 0.0503
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0052 0.0408 0.0408
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0014 0.0016 0.0016
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Echinococcus multilocularis sex peptide receptor 0.0029 0.0176 0.0176
Brugia malayi hypothetical protein 0.0158 0.1488 0.587
Echinococcus granulosus neurogenic locus protein delta 0.0018 0.0061 0.0061
Leishmania major dehydrogenase-like protein 0.0014 0.0016 0.0094
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0014 0.0016 0.0032
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0175 0.1661 1
Leishmania major short chain dehydrogenase/reductase, putative 0.0014 0.0016 0.0094
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0014 0.0016 0.0032
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0014 0.0016 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0014 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0693 0.1403
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0176 0.1051
Echinococcus granulosus peroxidasin 0.0056 0.0443 0.0443
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0014 0.0016 0.0016
Onchocerca volvulus 0.0014 0.0016 0.0093
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0176 0.0585
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.0113 0.103 0.6139
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0014 0.0014
Trypanosoma brucei Valosin-containing protein 0.0107 0.0971 0.5845
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Echinococcus granulosus RUN 0.0177 0.1678 0.1678
Plasmodium vivax cell division cycle ATPase, putative 0.0041 0.0295 0.1759
Onchocerca volvulus 0.0018 0.0061 0.0361
Echinococcus multilocularis Polycystic kidney disease protein 0.0177 0.1678 0.1678
Plasmodium vivax multidomain scavenger receptor, putative 0.0177 0.1678 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0014 0.0053
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0014 0.0016 0.0093
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni myosin xvIII 0.0029 0.0176 0.0176
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0176 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0014 0.0053
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0051 0.0392 0.0392
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0176 0.0585
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.5574
Mycobacterium ulcerans aldehyde dehydrogenase 0.008 0.0693 0.1403
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0027 0.015 0.1459
Brugia malayi dehydrogenases, short chain protein 2 0.0014 0.0016 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0014 0.0053
Toxoplasma gondii cell division protein CDC48CY 0.0113 0.103 0.6202
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0045
Onchocerca volvulus 0.0018 0.0061 0.0361
Trypanosoma brucei oxidoreductase-like protein 0.0014 0.0016 0.0094
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0176 0.0585
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0176 0.0176
Echinococcus multilocularis oxidoreductase 0.0014 0.0016 0.0016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0016 0.0016
Toxoplasma gondii oxidoreductase, putative 0.0014 0.0016 0.0094
Echinococcus granulosus g protein coupled receptor 0.0029 0.0176 0.0176
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0014 0.0016 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Echinococcus granulosus slit 2 protein 0.0018 0.0061 0.0061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0176 0.0695
Leishmania major short chain dehydrogenase-like protein 0.0014 0.0016 0.0094
Trypanosoma brucei short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Brugia malayi Temporarily assigned gene name protein 59 0.0051 0.0392 0.1548
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Loa Loa (eye worm) animal heme peroxidase 0.0056 0.0443 0.1472
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Brugia malayi hypothetical protein 0.0014 0.0016 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0014 0.0045
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0175 0.1661 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Schistosoma mansoni lipoxygenase 0.0677 0.6761 0.6761
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus granulosus steroid dehydrogenase 0.0014 0.0016 0.0016
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0176 0.0176
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0014 0.0014
Brugia malayi RE15519p 0.0029 0.0176 0.0695
Brugia malayi vesicle-fusing ATPase 0.0066 0.0554 0.2184
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Brugia malayi Melatonin receptor type 1A 0.0029 0.0176 0.0695
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0084 0.0503
Schistosoma mansoni neuropeptide receptor 0.0029 0.0176 0.0176
Echinococcus granulosus retinol dehydrogenase 11 0.0014 0.0016 0.0016
Mycobacterium ulcerans ketoacyl reductase 0.0014 0.0016 0.0032
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.004 0.0286 0.1129
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0176 0.0176
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0107 0.0971 0.5786
Echinococcus multilocularis carbonyl reductase 1 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Brugia malayi Latrophilin receptor protein 2 0.0013 0.0007 0.0028
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Schistosoma mansoni retinal dehydrogenase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Echinococcus multilocularis lipoxygenase domain containing protein 0.0177 0.1678 0.1678
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0176 0.0176
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0176 0.0176
Brugia malayi probable protein kinase 0.0173 0.1634 0.6445
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0061 0.0239
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0018 0.0061 0.0361
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0014 0.0016 0.0094
Onchocerca volvulus Chorion peroxidase homolog 0.0056 0.0443 0.2642
Onchocerca volvulus 0.0018 0.0061 0.0361
Mycobacterium tuberculosis Possible oxidoreductase 0.0014 0.0016 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0014 0.0016 0.0094
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Onchocerca volvulus 0.0029 0.0176 0.1051
Echinococcus multilocularis fibropellin Ia 0.0018 0.0061 0.0061
Schistosoma mansoni notch 0.0018 0.0061 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus granulosus neural cadherin 0.0018 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0052
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0176 0.0176
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0113 0.103 0.103
Brugia malayi GnHR receptor homolog 0.0029 0.0176 0.0695
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Schistosoma mansoni amine GPCR 0.0029 0.0176 0.0176
Brugia malayi Zinc finger, C2H2 type family protein 0.0068 0.0574 0.2265
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0014 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1735 0.1735
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0014 0.0053
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0014 0.0016 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0027 0.0157 0.0522
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0014 0.0014
Leishmania major short chain dehydrogenase/reductase, putative 0.0014 0.0016 0.0094
Onchocerca volvulus 0.0029 0.0176 0.1051
Brugia malayi Protein kinase domain containing protein 0.0052 0.0408 0.1611
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Onchocerca volvulus 0.0014 0.0016 0.0093
Trypanosoma cruzi short chain dehydrogenase, putative 0.0014 0.0016 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0176 0.0176
Echinococcus granulosus protein kinase 0.0122 0.1119 0.1119
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.5574
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0068 0.0574 0.1906
Echinococcus granulosus cpg binding protein 0.0031 0.0189 0.0189
Echinococcus multilocularis survival motor neuron protein 1 0.0158 0.1488 0.1488
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0032 0.0206 0.0814
Echinococcus granulosus Polycystic kidney disease protein 0.0177 0.1678 0.1678
Echinococcus granulosus lipoxygenase domain containing protein 0.0177 0.1678 0.1678
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0051 0.0392 0.0392
Echinococcus granulosus carbonyl reductase 1 0.0014 0.0016 0.0016
Entamoeba histolytica short chain dehydrogenase family protein 0.0014 0.0016 0.0052
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0176 0.0176
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0014 0.0014
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0014 0.0045
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0014 0.0053
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.4072 0.4072
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0176 0.0176
Schistosoma mansoni hypothetical protein 0.0018 0.0061 0.0061
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0162 0.1523 0.9079
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0014 0.0014
Trypanosoma brucei short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.008 0.0693 0.0693
Onchocerca volvulus Slit protein homolog 0.0018 0.0061 0.0361
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0052 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Trichomonas vaginalis spermatogenesis associated factor, putative 0.0113 0.103 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0171 0.1618 0.5372
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0176 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0061 0.0061
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0171 0.1618 0.1618
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0061 0.0239
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0176 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.0014 0.0016 0.0094
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0014 0.0016 0.0093
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0014 0.0016 0.0032
Onchocerca volvulus 0.0014 0.0016 0.0093
Brugia malayi hypothetical protein 0.0029 0.0176 0.0695
Brugia malayi hypothetical protein 0.0013 0.0011 0.0044
Brugia malayi transitional endoplasmic reticulum ATPase TER94, putative 0.0047 0.0354 0.1398
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0014 0.0016 0.0152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0176 0.0176
Schistosoma mansoni opsin-like receptor 0.0029 0.0176 0.0176
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0051 0.0392 0.2364
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0183 0.1735 0.5762
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Mycobacterium ulcerans ketoacyl reductase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0084 0.0508
Brugia malayi Animal haem peroxidase family protein 0.0056 0.0443 0.1749
Schistosoma mansoni opsin-like receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short-chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0052 0.0408 0.1355
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0051 0.0392 0.1303
Onchocerca volvulus 0.0014 0.0016 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Schistosoma mansoni hypothetical protein 0.0177 0.1678 0.1678
Brugia malayi oxidoreductase 0.0014 0.0016 0.0062
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0175 0.1661 1
Brugia malayi Animal haem peroxidase family protein 0.0056 0.0443 0.1749
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.1661 0.6552
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0068 0.0574 0.3457
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Schistosoma mansoni laminin gamma-3 chain 0.0018 0.0061 0.0061
Giardia lamblia High cysteine protein 0.0018 0.0061 0.0814
Schistosoma mansoni cell polarity protein 0.0018 0.0061 0.0061
Brugia malayi map kinase activated protein kinase protein 2 0.0183 0.1735 0.6846
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0014 0.0016 0.0016
Leishmania major oxidoreductase-like protein 0.0014 0.0016 0.0094
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0175 0.1661 0.6552
Leishmania major hypothetical protein, conserved 0.002 0.0084 0.0508
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0014 0.0016 0.0032
Schistosoma mansoni neuropeptide receptor 0.0029 0.0176 0.0176
Onchocerca volvulus 0.0014 0.0016 0.0093
Echinococcus multilocularis serotonin receptor 0.0029 0.0176 0.0176
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0068 0.0574 0.0574
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0068 0.0574 0.5574
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0176 0.0176
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0175 0.1661 0.3364
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Loa Loa (eye worm) pigment dispersing factor receptor c 0.004 0.0286 0.0951
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0176 0.0176
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0176 0.0176
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0014 0.0016 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0014 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0016 0.0094
Brugia malayi dehydrogenases, short chain protein 9 0.0014 0.0016 0.0062
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.2535 0.8416
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0201
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0014 0.0016 0.0052
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0176 0.0585
Loa Loa (eye worm) blistered cuticle protein 3 0.0056 0.0443 0.1472
Schistosoma mansoni hypothetical protein 0.0051 0.0392 0.0392
Echinococcus granulosus neuropeptide receptor 0.0029 0.0176 0.0176
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0176 0.0176
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0014 0.0016 0.0093
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0014 0.0016 0.0052
Brugia malayi Peroxidasin 0.0056 0.0443 0.1749
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0051 0.0392 0.2364
Brugia malayi EGF-like domain containing protein 0.0018 0.0061 0.0239
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0013 0.0007 0.0007
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0014 0.0016 0.0093
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0029 0.0176 0.0176
Schistosoma mansoni protein kinase 0.0122 0.1119 0.1119
Schistosoma mansoni hypothetical protein 0.0136 0.1266 0.1266
Loa Loa (eye worm) hypothetical protein 0.0177 0.1678 0.557
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Schistosoma mansoni hypothetical protein 0.0136 0.1266 0.1266
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0013 0.0007 0.0007
Onchocerca volvulus 0.0051 0.0392 0.234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Schistosoma mansoni peroxidasin 0.0056 0.0443 0.0443
Brugia malayi Animal haem peroxidase family protein 0.0056 0.0443 0.1749
Mycobacterium tuberculosis Putative conserved ATPase 0.0068 0.0567 0.1149
Echinococcus granulosus g protein coupled receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) dehydrogenase 0.0014 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0056 0.0443 0.1472
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0018 0.0061 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.1523 0.1523
Leishmania major quinonoid dihydropteridine reductase 0.0014 0.0016 0.0094
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0176 0.0176
Mycobacterium ulcerans short-chain dehydrogenase 0.0014 0.0016 0.0032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0014 0.0045
Schistosoma mansoni short chain dehydrogenase 0.0014 0.0016 0.0016
Onchocerca volvulus 0.0177 0.1678 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Onchocerca volvulus Sepiapterin reductase homolog 0.0014 0.0016 0.0093
Schistosoma mansoni biogenic amine receptor 0.0029 0.0176 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0014 0.0045
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Schistosoma mansoni steroid dehydrogenase 0.0014 0.0016 0.0016
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0176 0.0695
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0176 0.0176
Mycobacterium ulcerans short chain dehydrogenase 0.0014 0.0016 0.0032
Echinococcus granulosus protein jagged 2 0.0018 0.0061 0.0061
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0014 0.0016 0.0094
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0014 0.0016 0.0152
Echinococcus multilocularis microtubule associated protein 2 0.0696 0.6953 0.6953
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0176 0.0176
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0014 0.0016 0.0094
Brugia malayi Muscle positioning protein 4 0.0018 0.0061 0.0239
Trichomonas vaginalis steroid dehydrogenase, putative 0.0014 0.0016 0.0152
Echinococcus granulosus GPCR family 2 0.0013 0.0007 0.0007
Schistosoma mansoni amine GPCR 0.0029 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Leishmania major 3-keto-dihydrosphingosine reductase 0.0014 0.0016 0.0094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0176 0.0176
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0175 0.1661 0.3364
Echinococcus multilocularis notch 0.0018 0.0061 0.0061
Schistosoma mansoni amine GPCR 0.0029 0.0176 0.0176
Plasmodium falciparum dihydroorotate dehydrogenase 0.0175 0.1661 0.9899
Brugia malayi Animal haem peroxidase family protein 0.0056 0.0443 0.1749
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0014 0.0016 0.0016
Schistosoma mansoni loxhd1 0.0177 0.1678 0.1678
Echinococcus multilocularis protein jagged 2 0.0018 0.0061 0.0061
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0014 0.0016 0.0152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0176 0.0585
Mycobacterium tuberculosis Probable oxidoreductase 0.0014 0.0016 0.0032

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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