Detailed information for compound 689632

Basic information

Technical information
  • TDR Targets ID: 689632
  • Name: N-[3-(6-ethoxypyridazin-3-yl)phenyl]-3-nitrob enzenesulfonamide
  • MW: 400.408 | Formula: C18H16N4O5S
  • H donors: 1 H acceptors: 6 LogP: 2.53 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(nn1)c1cccc(c1)NS(=O)(=O)c1cccc(c1)[N+](=O)[O-]
  • InChi: 1S/C18H16N4O5S/c1-2-27-18-10-9-17(19-20-18)13-5-3-6-14(11-13)21-28(25,26)16-8-4-7-15(12-16)22(23)24/h3-12,21H,2H2,1H3
  • InChiKey: JWUKYRVZJLFUQM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[3-(6-ethoxypyridazin-3-yl)phenyl]-3-nitro-benzenesulfonamide
  • N-[3-(6-ethoxy-3-pyridazinyl)phenyl]-3-nitrobenzenesulfonamide
  • ZINC04270378

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.007 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Schistosoma mansoni smad 0.0053 0.0063 0.0063
Trichomonas vaginalis penicillin-binding protein, putative 0.0193 0.0344 0.1357
Loa Loa (eye worm) glutathione reductase 0.0233 0.0424 0.2265
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.0043 0.0043
Echinococcus multilocularis serine protein kinase ATM 0.0028 0.0014 0.0013
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0193 0.0344 0.1837
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0081 0.0119 0.1049
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0182 0.0323 0.1276
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.01 0.0158 0.1395
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0038 0.0033 0.1276
Leishmania major importin beta-1 subunit, putative 0.0023 0.0003 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Bromodomain containing protein 0.0084 0.0127 0.0676
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0038 0.0033 0.0033
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0081 0.0119 0.1049
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0194 0.0767
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0344 0.3035
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable dehydrogenase 0.053 0.1021 0.4036
Trichomonas vaginalis mercuric reductase, putative 0.0081 0.0119 0.0469
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0062 0.0081 0.0715
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Toxoplasma gondii hypothetical protein 0.0038 0.0033 0.0751
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0149 0.0255 0.2255
Schistosoma mansoni ferritin 0.0063 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.053 0.1021 0.4036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Leishmania major phosphatidylinositol 3-related kinase, putative 0.005 0.0057 0.0504
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0041 0.0222
Mycobacterium tuberculosis Conserved protein 0.0193 0.0344 0.1357
Loa Loa (eye worm) transcription factor SMAD2 0.0774 0.1509 0.8068
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0038 0.0033 0.0033
Leishmania major mitochondrial DNA polymerase beta 0.0586 0.1132 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Loa Loa (eye worm) Smad1 0.0053 0.0063 0.0337
Giardia lamblia NADH oxidase lateral transfer candidate 0.0081 0.0119 0.4654
Brugia malayi Smad1 0.0053 0.0063 0.0336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0135 0.0534
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0057 0.0225
Onchocerca volvulus 0.0193 0.0344 0.4447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0053
Brugia malayi jmjC domain containing protein 0.0043 0.0044 0.0233
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0043 0.0171
Schistosoma mansoni hypothetical protein 0.0328 0.0616 0.0616
Schistosoma mansoni cpg binding protein 0.0132 0.0223 0.0223
Brugia malayi hypothetical protein 0.0161 0.028 0.1494
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Schistosoma mansoni smad 0.0024 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.002 0.0079
Loa Loa (eye worm) hypothetical protein 0.0308 0.0576 0.3078
Brugia malayi Importin beta-1 subunit 0.0028 0.0014 0.0071
Brugia malayi hypothetical protein 0.0038 0.0033 0.0174
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.007 0.0099 0.0526
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0059 0.0234
Brugia malayi Cytochrome P450 family protein 0.0022 0.0002 0.0008
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0042 0.0041 0.1617
Schistosoma mansoni hypothetical protein 0.0038 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0002 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0586 0.1132 1
Trypanosoma brucei hypothetical protein, conserved 0.0193 0.0344 0.3035
Trichomonas vaginalis ap endonuclease, putative 0.01 0.0158 0.0624
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.007 0.0098 0.0866
Brugia malayi ubiquitin specific protease 14 0.0038 0.0033 0.0174
Echinococcus multilocularis GPCR, family 2 0.0302 0.0563 0.0563
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0059 0.0076 0.0405
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0041 0.0365
Brugia malayi Pre-SET motif family protein 0.0035 0.0027 0.0145
Brugia malayi intermediate filament protein 0.0053 0.0064 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0157 0.0621
Brugia malayi beta-lactamase 0.0193 0.0344 0.1836
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0351 0.0351
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.0454 0.0453
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0028 0.0014 0.0013
Brugia malayi hypothetical protein 0.0078 0.0113 0.0606
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0011 0.0254
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0005 0.0024
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0038 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0031 0.002 0.0459
Entamoeba histolytica hypothetical protein 0.0038 0.0033 0.1276
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0043 0.0231
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.0099 0.087
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0043 0.0231
Schistosoma mansoni hypothetical protein 0.005 0.0058 0.0058
Trichomonas vaginalis helicase, putative 0.0028 0.0013 0.0052
Echinococcus multilocularis ornithine aminotransferase 0.0182 0.0323 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0135 0.0534
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0043 0.0381
Schistosoma mansoni DNA polymerase eta 0.0043 0.0043 0.0043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0044 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0037 0.0146
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0063 0.0084 0.2591
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0002 0.0009
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0038 0.0033 0.0129
Schistosoma mansoni zinc finger protein 0.0027 0.0012 0.0012
Schistosoma mansoni apoferritin-2 0.0063 0.0084 0.0084
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0028 0.0014 0.0013
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0194 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0194 0.0767
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0122 0.108
Mycobacterium tuberculosis Putative ferredoxin reductase 0.053 0.1021 0.4036
Plasmodium vivax SET domain protein, putative 0.0035 0.0027 0.0642
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.005 0.0057 0.0057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0193 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0005
Brugia malayi RNA, U transporter 1 0.008 0.0117 0.0626
Trypanosoma brucei trypanothione reductase 0.0233 0.0424 0.3743
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.0446
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0586 0.1132 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0302 0.0563 0.0563
Echinococcus granulosus ornithine aminotransferase 0.0182 0.0323 0.0323
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Toxoplasma gondii ubiquitin-specific protease USP4 0.0038 0.0033 0.0751
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0076 0.0076
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.2664
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0022 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0024
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.01 0.0158 0.0158
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Brugia malayi beta-lactamase family protein 0.0193 0.0344 0.1836
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.1276
Brugia malayi Fli-1 protein 0.0241 0.0441 0.2356
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0193 0.0344 0.1357
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0038 0.0033 0.0769
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0142 0.0142
Mycobacterium ulcerans L-lysine aminotransferase 0.0182 0.0323 0.1276
Mycobacterium leprae Probable lipase LipE 0.0193 0.0344 0.1357
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0081 0.0119 0.3677
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0119 0.0196 0.0774
Trypanosoma cruzi PAB1-binding protein , putative 0.0161 0.028 0.2469
Echinococcus granulosus dna polymerase kappa 0.0043 0.0043 0.0043
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0043 0.0381
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0149 0.0255 0.2255
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0057 0.0225
Plasmodium falciparum glutathione reductase 0.0081 0.0119 0.2803
Onchocerca volvulus 0.0193 0.0344 0.4447
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0081 0.0119 0.2803
Plasmodium vivax glutathione reductase, putative 0.0233 0.0424 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0053 0.0063 0.0063
Brugia malayi PHD-finger family protein 0.0033 0.0023 0.0122
Echinococcus multilocularis inositol monophosphatase 1 0.0119 0.0196 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0063 0.0084 0.0331
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0064 0.0339
Leishmania major cytochrome p450-like protein 0.0022 0.0002 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0406 0.0773 0.413
Onchocerca volvulus 0.0038 0.0033 0.0422
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi trypanothione reductase, putative 0.0233 0.0424 0.3743
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.0043 0.1691
Giardia lamblia DINP protein human, muc B family 0.0043 0.0043 0.1691
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.007 0.0099 0.3858
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0027 0.0027
Mycobacterium ulcerans lipase LipD 0.0193 0.0344 0.1357
Trichomonas vaginalis glutathione reductase, putative 0.0081 0.0119 0.0469
Echinococcus multilocularis peregrin 0.0031 0.0019 0.0018
Echinococcus multilocularis expressed protein 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) fli-1 protein 0.0241 0.0441 0.2357
Brugia malayi Calcitonin receptor-like protein seb-1 0.0954 0.1871 1
Trichomonas vaginalis ubiquitin specific protease, putative 0.0038 0.0033 0.0129
Trypanosoma cruzi PAB1-binding protein , putative 0.0161 0.028 0.2469
Schistosoma mansoni smad1 5 8 and 0.0053 0.0063 0.0063
Schistosoma mansoni Smad4 0.0024 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0149 0.0255 0.1008
Onchocerca volvulus 0.0259 0.0476 0.6162
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0017 0.0145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0038 0.0033 0.0033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0308 0.0576 0.2275
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0072
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Echinococcus multilocularis expressed protein 0.0063 0.0084 0.0084
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0041 0.0222
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0302 0.0563 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0634 0.123 0.123
Schistosoma mansoni ferritin 0.0063 0.0084 0.0084
Schistosoma mansoni survival motor neuron protein 0.005 0.0058 0.0058
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0038 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.005 0.0057 0.0057
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0009 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0014 0.0076
Plasmodium vivax importin-beta 2, putative 0.0028 0.0014 0.0315
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0042 0.0041 0.0365
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0149 0.0255 0.2255
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0014 0.0119
Schistosoma mansoni Smad4 0.0053 0.0063 0.0063
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.002 0.0019
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.053 0.1021 0.4036
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0769
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.0454 0.0453
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ferritin light chain 0.0063 0.0084 0.0084
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0053
Echinococcus granulosus lamin 0.0053 0.0064 0.0063
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0149 0.0255 0.2255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable lipase LipD 0.0193 0.0344 0.1357
Brugia malayi hypothetical protein 0.0308 0.0576 0.3077
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0021 0.0021
Onchocerca volvulus 0.0053 0.0064 0.0822
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0082 0.0122 0.108
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0954 0.1871 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0014 0.0014
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0038 0.0033 0.0175
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0193 0.0344 0.1357
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0059 0.0234
Schistosoma mansoni lamin 0.0053 0.0064 0.0064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.3495
Echinococcus granulosus geminin 0.0328 0.0616 0.0615
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0182 0.0323 0.1276
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0064 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Echinococcus multilocularis cpg binding protein 0.0132 0.0223 0.0223
Plasmodium falciparum importin beta, putative 0.0028 0.0014 0.0315
Brugia malayi Ets-domain containing protein 0.0079 0.0117 0.0622
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0036 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0134 0.0527
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0022 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis lamin dm0 0.0053 0.0064 0.0063
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0277 0.0513 0.4533
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0182 0.0323 0.1276
Loa Loa (eye worm) hypothetical protein 0.0053 0.0063 0.0335
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0064 0.034
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0319
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0182 0.0323 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0057 0.0225
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Brugia malayi MH2 domain containing protein 0.0024 0.0005 0.0023
Plasmodium falciparum glutathione reductase 0.0233 0.0424 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0053 0.0063 0.0337
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Treponema pallidum NADH oxidase 0.0081 0.0119 0.7519
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0014 0.0313
Toxoplasma gondii hypothetical protein 0.0027 0.0011 0.0248
Brugia malayi MH1 domain containing protein 0.0053 0.0063 0.0336
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Entamoeba histolytica hypothetical protein 0.0078 0.0113 0.444
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0238 0.0434 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.059 0.114 0.4505
Loa Loa (eye worm) hypothetical protein 0.0078 0.0113 0.0604
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0033 0.1276
Echinococcus granulosus Smad4 0.0053 0.0063 0.0063
Schistosoma mansoni cellular tumor antigen P53 0.0406 0.0773 0.0773
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.01 0.0158 0.1395
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0351 0.0351
Echinococcus granulosus Aminotransferase class III 0.0182 0.0323 0.0323
Schistosoma mansoni calpain-7 (C02 family) 0.0038 0.0033 0.0033
Onchocerca volvulus 0.0308 0.0576 0.7452
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0351 0.0351
Entamoeba histolytica exodeoxyribonuclease III, putative 0.01 0.0158 0.6189
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0142 0.0142
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0038 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0014 0.0321
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Brugia malayi FAT domain containing protein 0.0022 0.0001 0.0004
Plasmodium falciparum thioredoxin reductase 0.0233 0.0424 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0038 0.0033 0.0033
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Trichomonas vaginalis ubiquitin specific protease, putative 0.0038 0.0033 0.0129
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0063 0.0084 0.0331
Echinococcus multilocularis Aminotransferase class III 0.0182 0.0323 0.0323
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0228 0.0228
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0954 0.1871 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Entamoeba histolytica recQ family helicase, putative 0.0022 0 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0119 0.0196 0.1731
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0182 0.0323 0.1276
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0038 0.0033 0.0129
Brugia malayi Bromodomain containing protein 0.0031 0.0019 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0057 0.0225
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0228 0.0227
Toxoplasma gondii hypothetical protein 0.0094 0.0147 0.3379
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0096
Brugia malayi follicle stimulating hormone receptor 0.0224 0.0406 0.217
Schistosoma mansoni lamin 0.0053 0.0064 0.0064
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Brugia malayi TAR-binding protein 0.0135 0.0228 0.1216
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0193 0.0344 0.1836
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0059 0.0059
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0028 0.0014 0.0528
Schistosoma mansoni hypothetical protein 0.0302 0.0563 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0081 0.0119 0.2803
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0194 0.0767
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0081 0.0119 0.1049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0149 0.0255 0.1008
Schistosoma mansoni ferritin 0.0063 0.0084 0.0084
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0042 0.0041 0.0041
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Plasmodium vivax ubiquitin specific protease, putative 0.0038 0.0033 0.0769
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0038 0.0033 0.0033
Schistosoma mansoni smad1 5 8 and 0.0053 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.007 0.0099 0.0098
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus expressed protein 0.0063 0.0084 0.0084
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0041 0.0974
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0041 0.0163
Echinococcus granulosus ferritin 0.0063 0.0084 0.0084
Loa Loa (eye worm) phosphatidylinositol 3 0.0149 0.0255 0.1365
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0033 0.0769
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.007 0.0099 0.0098
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.007 0.0099 0.0099
Trypanosoma brucei unspecified product 0.003 0.0017 0.0145
Toxoplasma gondii LsmAD domain-containing protein 0.0161 0.028 0.6444
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0344 0.1357
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.7147
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0046
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0 0.0003
Trichomonas vaginalis ferritin, putative 0.0063 0.0084 0.0331
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.007 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0119 0.0196 0.0774
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Schistosoma mansoni hypothetical protein 0.0302 0.0563 0.0563
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus granulosus beta LACTamase domain containing family member 0.0193 0.0344 0.0344
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Conserved protein 0.0193 0.0344 0.1357
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0018 0.0018
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0118 0.0195 0.1718
Echinococcus granulosus peregrin 0.0031 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0036 0.0036
Brugia malayi jmjC domain containing protein 0.0092 0.0142 0.076
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0038 0.0033 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Mycobacterium ulcerans beta-lactamase 0.0193 0.0344 0.1357
Echinococcus granulosus mothers against decapentaplegic 2 0.0024 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Plasmodium vivax ataxin-2 like protein, putative 0.0161 0.028 0.6597
Brugia malayi Pre-SET motif family protein 0.0228 0.0414 0.2211
Mycobacterium ulcerans hypothetical protein 0.0193 0.0344 0.1357
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ap endonuclease 0.01 0.0158 0.0158
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus granulosus snurportin 1 0.0299 0.0558 0.0558
Loa Loa (eye worm) programmed cell death 8 0.0021 0 0.0001
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0277 0.0513 0.4533
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0002 0.0013
Echinococcus multilocularis lamin 0.0053 0.0064 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0076 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0059 0.0234
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0212 0.0836
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.0063 0.0337
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.01 0.0158 0.0845
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0228 0.1216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0038 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0954 0.1871 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.3495
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0113 0.2602
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0082 0.0122 0.108
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0038 0.0033 0.0033
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0038 0.0033 0.0033
Leishmania major DNA polymerase eta, putative 0.0043 0.0043 0.0381
Echinococcus multilocularis geminin 0.0328 0.0616 0.0615
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0018 0.0018
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0119 0.0196 0.1731
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Echinococcus granulosus lamin dm0 0.0053 0.0064 0.0063
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.3495
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0041 0.0974
Brugia malayi hypothetical protein 0.0247 0.0454 0.2424
Treponema pallidum bacterioferrin (TpF1) 0.0063 0.0084 0.5299
Echinococcus granulosus inositol monophosphatase 1 0.0119 0.0196 0.0196
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0043 0.0043
Mycobacterium tuberculosis Probable lipase LipE 0.0193 0.0344 0.1357
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0014 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0193 0.0344 0.8109
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0193 0.0344 0.1357
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0193 0.0344 0.1357
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0113 0.2602
Onchocerca volvulus Alhambra homolog 0.0028 0.0014 0.0176
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Trichomonas vaginalis inositol monophosphatase, putative 0.0119 0.0196 0.0774
Echinococcus multilocularis ubiquitin specific protease 41 0.007 0.0099 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0074 0.0395
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0014 0.0313
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0149 0.0255 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0233 0.0424 0.1674
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0042 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0247 0.0454 0.2424
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0038 0.0033 0.0129
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0081 0.0119 0.0469
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.01 0.0158 0.1395
Mycobacterium ulcerans bacterioferritin BfrA 0.0063 0.0084 0.0331
Giardia lamblia Hypothetical protein 0.0038 0.0033 0.1276
Entamoeba histolytica hypothetical protein 0.0078 0.0113 0.444
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0032 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0149 0.0255 1
Loa Loa (eye worm) RNA binding protein 0.0135 0.0228 0.1217
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0063 0.0063
Brugia malayi MH2 domain containing protein 0.0774 0.1509 0.8068
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0228 0.1217
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0017 0.0145
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0038 0.0033 0.0769
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0081 0.0119 0.2803
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi RNA binding protein 0.0135 0.0228 0.1216
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0182 0.0323 0.1726
Schistosoma mansoni bromodomain containing protein 0.0072 0.0102 0.0102
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0038 0.0033 0.0033
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.0043 0.0232
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0182 0.0323 0.1276
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0027 0.0027
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0 0.0001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0119 0.0196 0.4518
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0081 0.0119 0.0119
Echinococcus multilocularis musashi 0.0053 0.0064 0.0063
Echinococcus granulosus serine protein kinase ATM 0.0028 0.0014 0.0013
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0224 0.0406 0.2171
Brugia malayi MH2 domain containing protein 0.0053 0.0063 0.0336
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium ulcerans esterase/lipase LipP 0.0193 0.0344 0.1357
Brugia malayi hypothetical protein 0.0104 0.0165 0.0883
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Onchocerca volvulus 0.005 0.0058 0.0755
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0038 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.01 0.0158 0.489
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.005 0.0057 0.0057
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0081 0.0119 0.0469
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0 0.0002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0081 0.0119 0.1049
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0 0.0007
Echinococcus multilocularis mothers against decapentaplegic 6 0.0024 0.0005 0.0004
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0038 0.0033 0.0769
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0 0.0001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0117 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0277 0.0513 0.4533
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.01 0.0158 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0038 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0038 0.0033 0.0751
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0076 0.067
Loa Loa (eye worm) nuclear factor I 0.0029 0.0016 0.0084
Entamoeba histolytica hypothetical protein 0.0028 0.0014 0.0528
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.0351 0.1874
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0014 0.0014
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0081 0.0119 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Echinococcus multilocularis tumor protein p63 0.2777 0.5528 0.5528
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0081 0.0119 0.2738
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Loa Loa (eye worm) hypothetical protein 0.0022 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0054 0.0289
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0038 0.0033 0.0033
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0118 0.0195 0.1718
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0038 0.0033 0.0769
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0119 0.0196 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Schistosoma mansoni importin beta-1 0.0028 0.0014 0.0014
Plasmodium vivax ornithine aminotransferase, putative 0.0182 0.0323 0.7624
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0081 0.0119 0.0469
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Toxoplasma gondii ABC1 family protein 0.0193 0.0344 0.7921
Toxoplasma gondii NADPH-glutathione reductase 0.0081 0.0119 0.2738
Trypanosoma brucei unspecified product 0.0043 0.0043 0.0381
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0014 0.0013
Echinococcus multilocularis snurportin 1 0.0299 0.0558 0.0558
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0024 0.0005 0.0056
Giardia lamblia DUB-1 0.0038 0.0033 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Schistosoma mansoni inositol monophosphatase 0.0119 0.0196 0.0196
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0038 0.0033 0.0033
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0044 0.0234
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0043 0.0171
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni cpg binding protein 0.0123 0.0205 0.0205
Mycobacterium ulcerans hypothetical protein 0.0308 0.0576 0.2275
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0586 0.1132 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0027 0.0627
Loa Loa (eye worm) inositol-1 0.0119 0.0196 0.1048
Echinococcus granulosus importin subunit beta 1 0.0028 0.0014 0.0013
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0182 0.0323 0.1276
Mycobacterium tuberculosis Probable hydrolase 0.0193 0.0344 0.1357
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0232
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0038 0.0033 0.1276
Trypanosoma brucei unspecified product 0.003 0.0017 0.0145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0038 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.007 0.0099 0.0389
Brugia malayi MH1 domain containing protein 0.0029 0.0016 0.0083
Mycobacterium tuberculosis Probable oxidoreductase 0.059 0.114 0.4505
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0193 0.0344 0.0344
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni inositol monophosphatase 0.0119 0.0196 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Loa Loa (eye worm) hypothetical protein 0.0068 0.0093 0.05
Brugia malayi Probable ClpP-like protease 0.0078 0.0113 0.0603
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0059 0.0076 0.0405
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0081 0.0119 0.3677
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0002 0.0009
Echinococcus granulosus zinc finger protein 0.0027 0.0012 0.0012
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.1283 0.2531 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0038 0.0033 0.0033
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0 0.0007
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0113 0.0446
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni Smad4 0.0024 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0113 0.0113
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0021 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.0099 0.087
Toxoplasma gondii exonuclease III APE 0.01 0.0158 0.3641
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0053 0.0063 0.0063
Brugia malayi Latrophilin receptor protein 2 0.0302 0.0563 0.3007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Schistosoma mansoni gabp alpha 0.0079 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0149 0.0255 0.0255
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0013 0.0052
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0018 0.0018
Plasmodium falciparum thioredoxin reductase 0.0081 0.0119 0.2803
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0119 0.0196 0.6067
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0 0.0003
Schistosoma mansoni fkbp-rapamycin associated protein 0.0028 0.0014 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0044 0.0044
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0149 0.0255 0.0255
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0042 0.0041 0.0041
Echinococcus multilocularis zinc finger protein 0.0027 0.0012 0.0012
Onchocerca volvulus 0.0193 0.0344 0.4447
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0182 0.0323 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0194 0.0767
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Loa Loa (eye worm) latrophilin receptor protein 2 0.0302 0.0563 0.3008
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0038 0.0033 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0038 0.0033 0.0751
Mycobacterium leprae conserved hypothetical protein 0.0193 0.0344 0.1357
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0344 0.1357
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0302 0.0563 0.3007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0095 0.0095
Brugia malayi Bromodomain containing protein 0.004 0.0037 0.0195
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.0031 0.002 0.0107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0302 0.0563 0.0563
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Echinococcus multilocularis dnaJ subfamily B 0.1295 0.2555 0.2555
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0149 0.0255 0.2255
Loa Loa (eye worm) beta-lactamase 0.0193 0.0344 0.1837
Echinococcus granulosus tar DNA binding protein 0.0135 0.0228 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus mothers against decapentaplegic 6 0.0024 0.0005 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0113 0.0113
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.0043 0.0043
Mycobacterium tuberculosis Conserved protein 0.0193 0.0344 0.1357
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0011 0.0254
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0072 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0769
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Entamoeba histolytica hypothetical protein 0.0078 0.0113 0.444
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Mycobacterium ulcerans hypothetical protein 0.1283 0.2531 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0038 0.0033 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.01 0.0158 0.3728
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.005 0.0057 0.0504
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0 0.0007
Brugia malayi Thioredoxin reductase 0.0233 0.0424 0.2265
Schistosoma mansoni hypothetical protein 0.0072 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0078 0.0113 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0344 0.3035
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0043 0.0171
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.1283 0.2531 1
Echinococcus granulosus smad 0.0053 0.0063 0.0063
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0057 0.0306
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0769
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0038 0.0033 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0299 0.0558 0.0558
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0038 0.0033 0.0129
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Schistosoma mansoni ap endonuclease 0.01 0.0158 0.0158
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0117 0.0116
Leishmania major hypothetical protein, conserved 0.0161 0.028 0.2469
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0076 0.03
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0028 0.0014 0.0119
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0081 0.0119 0.3677
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Onchocerca volvulus 0.0406 0.0773 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0081 0.0119 0.1049
Echinococcus granulosus dnaJ subfamily B 0.1295 0.2555 0.2555
Schistosoma mansoni peptidase 0.0038 0.0033 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Brugia malayi MH1 domain containing protein 0.0029 0.0016 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0038 0.0033 0.0174
Onchocerca volvulus 0.0035 0.0027 0.0352
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.1283 0.2531 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0043 0.0171
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0014 0.0072
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.059 0.114 0.4505
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0014 0.0075
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0182 0.0323 0.1276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.004 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0043 0.0171
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.01 0.0158 0.0624
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0057 0.0305
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0038 0.0033 0.0033
Onchocerca volvulus 0.0123 0.0205 0.2651
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0351 0.0351
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0113 0.0113
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0063 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Schistosoma mansoni ferritin light chain 0.0063 0.0084 0.0084
Plasmodium falciparum ornithine aminotransferase 0.0182 0.0323 0.7624
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.007 0.0099 0.0389
Loa Loa (eye worm) thioredoxin reductase 0.0233 0.0424 0.2265
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.01 0.0158 0.6189
Echinococcus granulosus TGF beta signal transducer SmadC 0.0053 0.0063 0.0063
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0057 0.0504
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.01 0.0159 0.14
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0013 0.0052
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0028 0.0014 0.0014
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0076 0.0405
Schistosoma mansoni calpain-7 (C02 family) 0.0038 0.0033 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0001 0.0003
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0182 0.0323 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.059 0.114 0.4505
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0011 0.0043
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1231 0.2426 0.9587
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Treponema pallidum exodeoxyribonuclease (exoA) 0.01 0.0158 1
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0038 0.0033 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0351 0.0351
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0041 0.0163
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Onchocerca volvulus 0.0038 0.0033 0.0422
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0634 0.123 0.123
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0014 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0182 0.0323 0.1276
Loa Loa (eye worm) CXXC zinc finger family protein 0.0123 0.0205 0.1096
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0036
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0038 0.0033 0.0769
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0263 0.0485 0.0485
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0351 0.0351
Echinococcus multilocularis smad 0.0053 0.0063 0.0063
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0043 0.0171
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.01 0.0158 0.3728
Loa Loa (eye worm) hypothetical protein 0.0042 0.0042 0.0223
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0009 0.0008
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Entamoeba histolytica hypothetical protein 0.0023 0.0003 0.0106
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0021 0.0021
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1744 0.3456 0.3456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Entamoeba histolytica hypothetical protein 0.0078 0.0113 0.444
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0038 0.0033 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0041 0.0365
Trichomonas vaginalis penicillin-binding protein, putative 0.0193 0.0344 0.1357
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0014 0.0014
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0751
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0038 0.0033 0.0175
Leishmania major phosphatidylinositol 3-kinase, putative 0.005 0.0057 0.0504
Plasmodium falciparum phd finger protein, putative 0.0028 0.0014 0.0321
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0652 0.1265 0.1265
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi CXXC zinc finger family protein 0.0123 0.0205 0.1095
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0182 0.0323 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Loa Loa (eye worm) hypothetical protein 0.0052 0.0062 0.033
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0081 0.0119 0.1049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0151 0.0595
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.0351 0.1875
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0161 0.028 0.6597
Loa Loa (eye worm) hypothetical protein 0.0073 0.0104 0.0554
Leishmania major hypothetical protein, conserved 0.0193 0.0344 0.3035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax thioredoxin reductase, putative 0.0233 0.0424 1
Trypanosoma brucei PAB1-binding protein , putative 0.0161 0.028 0.2469
Schistosoma mansoni intermediate filament proteins 0.0053 0.0064 0.0064
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0076 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0059 0.0314
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.005 0.0057 0.0504
Loa Loa (eye worm) hypothetical protein 0.0652 0.1265 0.6764
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0038 0.0033 0.0769
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0014 0.0308
Giardia lamblia GTOR 0.0149 0.0255 1
Onchocerca volvulus 0.0038 0.0033 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Echinococcus multilocularis Smad4 0.0053 0.0063 0.0063
Toxoplasma gondii target of rapamycin (TOR), putative 0.0111 0.0179 0.4123
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0074
Toxoplasma gondii thioredoxin reductase 0.0233 0.0424 0.9767
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0044 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.007 0.0099 0.087
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0119 0.0196 0.1731
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0014 0.0118
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0113 0.0113
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0113 0.0113
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0003 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0161 0.028 0.6597
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0072 0.0102 0.0102
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0095 0.0095
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.0043 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0038 0.0033 0.0033
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0038 0.0033 0.0033
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0082 0.0122 0.108
Schistosoma mansoni hypothetical protein 0.0302 0.0563 0.0563
Echinococcus granulosus thioredoxin glutathione reductase 0.0233 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0053 0.0064 0.034
Mycobacterium ulcerans bacterioferritin BfrB 0.0063 0.0084 0.0331
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.01 0.0158 0.1395
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0182 0.0323 0.7447
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0228 0.0414 0.2212
Schistosoma mansoni hypothetical protein 0.0328 0.0616 0.0616
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0038 0.0033 0.0033
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0 0.0003
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0038 0.0033 0.0751
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0038 0.0033 0.0033
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0042 0.0041 0.0221
Brugia malayi MH2 domain containing protein 0.0053 0.0063 0.0336
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0002 0.0013
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0228 0.1217
Schistosoma mansoni smad1 5 8 and 0.0053 0.0063 0.0063
Brugia malayi glutathione reductase 0.0233 0.0424 0.2265
Echinococcus multilocularis dna polymerase eta 0.0043 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0028 0.0014 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0118 0.0466
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0043 0.0381
Echinococcus multilocularis ferritin 0.0063 0.0084 0.0084
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0113 0.0446
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0059 0.0059
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0014 0.0118
Mycobacterium ulcerans acetylornithine aminotransferase 0.0182 0.0323 0.1276
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0017 0.0145
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0302 0.0563 0.0563
Trichomonas vaginalis esterase, putative 0.0193 0.0344 0.1357
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0119 0.0196 0.7679
Loa Loa (eye worm) hypothetical protein 0.007 0.0099 0.0527
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0038 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0182 0.0323 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0081 0.0119 0.0469
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0061 0.0326
Schistosoma mansoni cpg binding protein 0.0132 0.0223 0.0223
Brugia malayi Ets-domain containing protein 0.0079 0.0117 0.0622
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0038 0.0033 0.1276
Onchocerca volvulus 0.0053 0.0064 0.0822
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0057 0.0504
Schistosoma mansoni hypothetical protein 0.0028 0.0014 0.0014
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0038 0.0033 0.0288
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0107 0.0171 0.0675
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.007 0.0099 0.0098
Brugia malayi Cytochrome P450 family protein 0.0022 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0161 0.028 0.1495
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0 0.0001
Echinococcus granulosus mothers against decapentaplegic 5 0.0053 0.0063 0.0063
Echinococcus granulosus ubiquitin specific protease 41 0.007 0.0099 0.0098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.053 0.1021 0.4036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0032 0.0031
Echinococcus multilocularis mothers against decapentaplegic 2 0.0024 0.0005 0.0004
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0058 0.0308
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0228 0.0228
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0038 0.0033 0.0033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi Cytochrome P450 family protein 0.0051 0.0059 0.0313
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0179 0.0707
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0002 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0134 0.0527
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0 0.0012
Schistosoma mansoni apoferritin-2 0.0063 0.0084 0.0084
Plasmodium falciparum ubiquitin specific protease, putative 0.0038 0.0033 0.0769
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0038 0.0033 0.0033
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.053 0.1021 0.4036
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0038 0.0033 0.0033
Leishmania major trypanothione reductase 0.0233 0.0424 0.3743
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0119 0.0196 0.1731
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0081 0.0119 0.2803
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0182 0.0323 0.1276
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0038 0.0033 0.0033
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0038 0.0033 0.0033
Plasmodium falciparum ubiquitin specific protease, putative 0.0038 0.0033 0.0769
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0149 0.0255 0.1008
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0038 0.0033 0.0033
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0107 0.0171 0.0675
Schistosoma mansoni hypothetical protein 0.1295 0.2555 0.2555
Brugia malayi mothers against decapentaplegic homolog 3 0.0024 0.0005 0.0023
Echinococcus multilocularis ornithine aminotransferase 0.0182 0.0323 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Echinococcus multilocularis thioredoxin glutathione reductase 0.0233 0.0425 0.0425
Mycobacterium tuberculosis Probable aminotransferase 0.1283 0.2531 1
Trichomonas vaginalis set domain proteins, putative 0.0259 0.0476 0.1881
Toxoplasma gondii FATC domain-containing protein 0.0028 0.0014 0.0311
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.1283 0.2531 1
Mycobacterium tuberculosis Probable esterase LipL 0.0193 0.0344 0.1357
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0038 0.0033 0.0769
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Trypanosoma cruzi trypanothione reductase, putative 0.0081 0.0119 0.1049
Brugia malayi Bloom's syndrome protein homolog 0.0022 0 0.0002
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0011 0.0681
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0058 0.0312
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0038 0.0033 0.0033
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0081 0.0119 0.0119
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0081 0.0119 0.0635
Echinococcus multilocularis beta LACTamase domain containing family member 0.0193 0.0344 0.0344
Schistosoma mansoni microtubule-associated protein tau 0.5006 1 1
Echinococcus granulosus intermediate filament protein 0.0053 0.0064 0.0063
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0038 0.0033 0.0769
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0038 0.0033 0.0033
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0149 0.0255 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0038 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0351 0.0351
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0038 0.0033 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Brugia malayi MH1 domain containing protein 0.0053 0.0063 0.0336
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0043 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0057 0.0225
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0081 0.0119 0.1049
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.007 0.0099 0.3858
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0033 0.0129
Schistosoma mansoni ets-related 0.0241 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0175
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0042 0.0041 0.0951
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0135 0.0534
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0038 0.0033 0.1276
Loa Loa (eye worm) hypothetical protein 0.004 0.0037 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0042 0.0041 0.0365
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0042 0.0041 0.0221
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0038 0.0033 0.0033
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.01 0.0158 0.0158
Brugia malayi PHD-finger family protein 0.0028 0.0014 0.0073
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0033 0.0288
Echinococcus granulosus tumor protein p63 0.2777 0.5528 0.5528
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0038 0.0033 0.0033
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0043 0.0381
Entamoeba histolytica protein kinase rad3, putative 0.0028 0.0014 0.0528
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0 0.0001
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0769
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Loa Loa (eye worm) RecQ helicase 0.0022 0 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0344 0.1357
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0038 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0073
Echinococcus multilocularis microtubule associated protein 2 0.5006 1 1
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0104 0.0104
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.007 0.0099 0.087
Giardia lamblia PHD finger protein 15 0.0028 0.0014 0.0533
Trichomonas vaginalis ap endonuclease, putative 0.01 0.0158 0.0624
Echinococcus granulosus ubiquitin specific peptidase c family 0.0038 0.0033 0.0033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0033 0.0288
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0228 0.0228
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0149 0.0255 0.2255
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0053 0.0063 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0005 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Brugia malayi latrophilin 2 splice variant baaae 0.0652 0.1265 0.6763
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0038 0.0033 0.0033
Leishmania major DNA polymerase kappa, putative 0.0043 0.0043 0.0381
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0033 0.0174
Brugia malayi beta-lactamase family protein 0.0193 0.0344 0.1836
Echinococcus granulosus cpg binding protein 0.0132 0.0223 0.0223
Brugia malayi Inositol-1 0.0119 0.0196 0.1047
Schistosoma mansoni ferritin 0.0063 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0193 0.0344 0.1837
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0119 0.1049
Loa Loa (eye worm) hypothetical protein 0.0302 0.0563 0.3008
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0099 0.0389
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0038 0.0033 0.0033
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0081 0.0119 0.1049
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0076 0.03
Loa Loa (eye worm) MH2 domain-containing protein 0.0774 0.1509 0.8068
Trichomonas vaginalis ubiquitin specific protease, putative 0.0038 0.0033 0.0129
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0117 0.0623
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0033 0.0129
Mycobacterium tuberculosis Probable reductase 0.053 0.1021 0.4036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0013 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0038 0.0033 0.0033
Trypanosoma cruzi target of rapamycin kinase 3 0.0118 0.0195 0.1718
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0043 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0013 0.0052
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0063 0.0084 0.0331
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0302 0.0563 0.0563
Echinococcus granulosus dna polymerase eta 0.0043 0.0043 0.0043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0038 0.0033 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0033 0.1276
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.0558 0.2982
Echinococcus granulosus GPCR family 2 0.0302 0.0563 0.0563
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0113 0.2664
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0149 0.0255 0.1364
Brugia malayi exodeoxyribonuclease III family protein 0.01 0.0158 0.0844

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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