Detailed information for compound 70990

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 348.481 | Formula: C23H28N2O
  • H donors: 0 H acceptors: 0 LogP: 5.7 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(OCCCN2CCCCC2)ccc1c1cc2n(c1)cccc2
  • InChi: 1S/C23H28N2O/c1-19-16-22(26-15-7-13-24-11-4-2-5-12-24)9-10-23(19)20-17-21-8-3-6-14-25(21)18-20/h3,6,8-10,14,16-18H,2,4-5,7,11-13,15H2,1H3
  • InChiKey: PMMBDDSXHUVMDX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histamine receptor H3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CK1 family protein kinase 0.0306 0.0495 0.2075
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0318 0.0529 0.4989
Schistosoma mansoni tyrosine kinase 0.0495 0.1042 0.1042
Toxoplasma gondii NEK kinase 0.014 0.0015 0.0067
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0461 0.0942 0.1265
Echinococcus granulosus dual specificity mitogen activated protein 0.0259 0.0359 0.0401
Giardia lamblia Kinase, CMGC SRPK 0.0212 0.0224 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0328 0.0328
Loa Loa (eye worm) hypothetical protein 0.0287 0.0439 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0101 0.0101
Giardia lamblia Kinase, CMGC CK2 0.0316 0.0522 0.2436
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.017 0.0101 0.0101
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Schistosoma mansoni protein kinase C 0.0139 0.0012 0.0012
Echinococcus multilocularis protein tyrosine kinase 0.125 0.322 0.4323
Brugia malayi Protein kinase domain containing protein 0.1365 0.3553 0.3553
Brugia malayi serine/threonine-protein kinase plk-2 0.0861 0.2098 0.2098
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0375 0.0695 0.3267
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.017 0.0101 0.0101
Echinococcus multilocularis serine:threonine protein kinase 0.036 0.0652 0.0875
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0497 0.1045 0.4948
Echinococcus multilocularis aurora kinase A 0.0461 0.0942 0.1265
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.026 0.0361 0.1661
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0222 0.0251 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0695 0.0695
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0495 0.1042 0.1399
Schistosoma mansoni protein kinase 0.0855 0.2081 0.2081
Trichomonas vaginalis AGC family protein kinase 0.0264 0.0374 0.1554
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Echinococcus multilocularis tyrosine protein kinase Blk 0.0403 0.0775 0.104
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0316 0.0522 0.0522
Loa Loa (eye worm) gastrulation defective protein 1 0.014 0.0016 0.0016
Loa Loa (eye worm) AUR protein kinase 0.0461 0.0942 0.0942
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0495 0.1042 0.1164
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.112 0.112
Giardia lamblia Kinase, STE STE20 0.0259 0.0359 0.1654
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0139 0.0012 0.0016
Echinococcus granulosus tyrosine protein kinase HCK 0.0309 0.0503 0.0562
Giardia lamblia Kinase, NEK 0.0431 0.0856 0.4038
Trypanosoma cruzi casein kinase, putative 0.0306 0.0495 0.2304
Entamoeba histolytica protein kinase, putative 0.0482 0.1003 0.4311
Brugia malayi Doublecortin family protein 0.0363 0.066 0.066
Echinococcus granulosus myotubularin protein 13 0.0158 0.0068 0.0076
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0194 0.0172 0.0741
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.017 0.0101 0.0371
Giardia lamblia Kinase, CMGC CDK 0.0375 0.0695 0.3267
Schistosoma mansoni cell adhesion molecule 0.0139 0.0012 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0299 0.0474 0.0474
Echinococcus multilocularis mitogen activated protein kinase 11 0.064 0.1459 0.1958
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0256 0.035 0.035
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0215 0.0232 0.0259
Echinococcus granulosus protein kinase c epsilon type 0.0659 0.1515 0.1692
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0479 0.0993 0.0993
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0283 0.043 0.048
Toxoplasma gondii casein kinase I 0.0306 0.0495 0.2191
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0149 0.004 0.004
Echinococcus granulosus contactin 0.0139 0.0012 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0263 0.0371 0.1708
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0182 0.0136 0.0183
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Giardia lamblia Kinase, AGC PKA 0.0318 0.0529 0.2468
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0182 0.0136 0.0152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0373 0.0373
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0262 0.0367 0.041
Trichomonas vaginalis STE family protein kinase 0.0266 0.0379 0.1575
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.052 0.1114 0.1114
Echinococcus multilocularis casein kinase ii subunit alpha 0.0316 0.0522 0.0701
Trypanosoma cruzi aurora B kinase, putative 0.0461 0.0942 0.4453
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0262 0.0367 0.1521
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Echinococcus granulosus epidermal growth factor receptor 0.1265 0.3264 0.3645
Giardia lamblia Kinase, CAMK CAMKL 0.0257 0.0352 0.1619
Giardia lamblia Kinase, CK1 Casein kinase 0.0306 0.0495 0.2304
Trypanosoma cruzi casein kinase, putative 0.0306 0.0495 0.2304
Brugia malayi Casein kinase II, alpha chain 0.0316 0.0522 0.0522
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0461 0.0942 0.405
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0461 0.0942 0.8999
Entamoeba histolytica cell division protein kinase 2, putative 0.0384 0.072 0.3093
Loa Loa (eye worm) hypothetical protein 0.0158 0.0068 0.0068
Brugia malayi Protein kinase domain containing protein 0.0299 0.0474 0.0474
Echinococcus multilocularis cyclin dependent kinase 9 0.0157 0.0065 0.0087
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0393 0.0745 0.1
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0942 0.4011
Plasmodium falciparum protein kinase, putative 0.0221 0.025 0.2283
Leishmania major protein kinase, putative 0.0369 0.0678 0.3183
Entamoeba histolytica protein kinase 2, putative 0.0497 0.1045 0.4493
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1208 0.31 0.4161
Brugia malayi Sex muscle abnormal protein 5 0.0186 0.0149 0.0149
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0259 0.0359 0.1654
Schistosoma mansoni protein kinase 0.0201 0.0191 0.0191
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0495 0.1042 0.1399
Trichomonas vaginalis CAMK family protein kinase 0.04 0.0765 0.3246
Schistosoma mansoni serine/threonine-protein kinase 0.052 0.1114 0.1114
Entamoeba histolytica protein kinase, putative 0.0256 0.035 0.1503
Plasmodium falciparum casein kinase 2, alpha subunit 0.0316 0.0522 0.4923
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0229 0.0272 0.0272
Echinococcus granulosus casein kinase I gamma 0.0299 0.0474 0.0529
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0264 0.0374 0.0374
Brugia malayi Immunoglobulin I-set domain containing protein 0.0139 0.0012 0.0012
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0855 0.2081 0.2324
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.052 0.1114 0.1114
Brugia malayi Protein kinase domain containing protein 0.0165 0.0087 0.0087
Echinococcus multilocularis dual specificity mitogen activated protein 0.0259 0.0359 0.0483
Echinococcus multilocularis activin receptor type 0.0614 0.1384 0.1858
Echinococcus multilocularis mitogen activated protein kinase 3 0.0263 0.0371 0.0498
Echinococcus multilocularis Glutaredoxin protein 5 0.0396 0.0756 0.1014
Loa Loa (eye worm) hypothetical protein 0.0262 0.0367 0.0367
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Trichomonas vaginalis STE family protein kinase 0.027 0.0392 0.163
Schistosoma mansoni cell adhesion molecule 0.032 0.0534 0.0534
Loa Loa (eye worm) CDC7 protein kinase 0.0227 0.0267 0.0267
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.064 0.1459 0.6932
Plasmodium falciparum calcium-dependent protein kinase 2 0.0262 0.0367 0.3412
Echinococcus multilocularis tyrosine protein kinase Abl 0.0477 0.0988 0.1326
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0149 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.065 0.1489 0.1663
Schistosoma mansoni tyrosine kinase 0.0564 0.1239 0.1239
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0263 0.0371 0.1708
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0479 0.0993 0.111
Trichomonas vaginalis CMGC family protein kinase 0.0375 0.0695 0.2943
Onchocerca volvulus 0.0593 0.1325 0.3104
Echinococcus granulosus tyrosine protein kinase Srms 0.0215 0.0232 0.0259
Echinococcus granulosus insulin receptor 0.1411 0.3686 0.4117
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0475 0.0984 0.0984
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0306 0.0495 0.0495
Echinococcus granulosus defective proboscis extension response 0.0242 0.0309 0.0345
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0262 0.0367 0.1624
Schistosoma mansoni kinase 0.0149 0.004 0.004
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0498 0.105 0.105
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0219 0.0242 0.109
Echinococcus multilocularis epidermal growth factor receptor 0.1932 0.5191 0.6969
Loa Loa (eye worm) TK/ALK protein kinase 0.0945 0.2342 0.2342
Echinococcus granulosus hypothetical protein 0.0269 0.0388 0.0433
Entamoeba histolytica protein kinase domain containing protein 0.0316 0.0522 0.2245
Echinococcus multilocularis titin 0.0184 0.0141 0.0189
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.0591
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0457 0.093 0.093
Schistosoma mansoni serine/threonine protein kinase 0.0314 0.0518 0.0518
Leishmania major protein kinase A catalytic subunit isoform 1 0.0318 0.0529 0.2468
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0407 0.0787 0.0879
Loa Loa (eye worm) hypothetical protein 0.0761 0.181 0.181
Trichomonas vaginalis CMGC family protein kinase 0.0407 0.0787 0.3338
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0371 0.1538
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.3596 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0495 0.1042 0.1399
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0598 0.2568
Brugia malayi casein kinase 1, delta 0.0306 0.0495 0.0495
Echinococcus multilocularis growth factor receptor bound protein 2 0.0186 0.0149 0.0201
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.065 0.1489 0.1999
Schistosoma mansoni protein kinase 0.027 0.0392 0.0392
Echinococcus granulosus calcium activated potassium channel 0.0387 0.0729 0.0814
Loa Loa (eye worm) hypothetical protein 0.0528 0.1135 0.1135
Loa Loa (eye worm) AGC/PKA protein kinase 0.0318 0.0529 0.0529
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0738 0.1744 0.1744
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0146 0.0032 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0267 0.1088
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0369 0.0678 0.0678
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0284 0.043 0.0578
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Schistosoma mansoni tyrosine kinase 0.0238 0.0297 0.0297
Entamoeba histolytica protein kinase domain containing protein 0.0461 0.0942 0.405
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.027 0.0392 0.0526
Onchocerca volvulus 0.1421 0.3716 0.8758
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Schistosoma mansoni serine/threonine protein kinase 0.0809 0.1949 0.1949
Loa Loa (eye worm) hypothetical protein 0.0275 0.0405 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0208 0.021 0.1894
Entamoeba histolytica protein kinase, putative 0.0461 0.0942 0.405
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Trichomonas vaginalis CMGC family protein kinase 0.0369 0.0678 0.2867
Echinococcus multilocularis dual specificity 0.0219 0.0242 0.0325
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0248 0.0328 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0015 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus multilocularis serine:threonine protein kinase 3 0.0818 0.1973 0.2649
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0328 0.0328
Leishmania major protein kinase, putative 0.0369 0.0678 0.3183
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0356 0.0639 0.0639
Trypanosoma cruzi p21-activated kinase 3, putative 0.017 0.0101 0.0415
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0212 0.0224 0.0902
Trichomonas vaginalis AGC family protein kinase 0.0318 0.0529 0.2224
Trichomonas vaginalis AGC family protein kinase 0.059 0.1314 0.5618
Loa Loa (eye worm) thyroid receptor interactor 0.0252 0.034 0.034
Echinococcus multilocularis mitogen activated protein kinase 11 0.064 0.1459 0.1958
Schistosoma mansoni serine/threonine protein kinase 0.1258 0.3245 0.3245
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0306 0.0495 0.0495
Plasmodium falciparum calcium-dependent protein kinase 1 0.0262 0.0367 0.3412
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Trypanosoma brucei protein kinase, putative 0.0221 0.025 0.1018
Echinococcus multilocularis rac serine:threonine kinase 0.052 0.1114 0.1495
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Trypanosoma brucei protein kinase, putative 0.0272 0.0395 0.1644
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.057 0.1258 0.1258
Loa Loa (eye worm) casein kinase 0.0198 0.0184 0.0184
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0206 0.0205 0.0912
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.027 0.0392 0.0438
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Brugia malayi Temporarily assigned gene name protein 59 0.0413 0.0805 0.0805
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0219 0.0242 0.109
Trypanosoma cruzi casein kinase, putative 0.0306 0.0495 0.2304
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Trypanosoma cruzi cdc2-related kinase 3 0.0375 0.0695 0.3267
Plasmodium falciparum cGMP-dependent protein kinase 0.0327 0.0555 0.5243
Brugia malayi Furin-like cysteine rich region family protein 0.1932 0.5191 0.5191
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0557 0.122 0.1363
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0256 0.035 0.047
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.079 0.1892 0.1892
Echinococcus granulosus fibroblast growth factor receptor 4 0.0756 0.1796 0.2006
Brugia malayi Protein kinase domain containing protein 0.1027 0.2577 0.2577
Entamoeba histolytica protein kinase domain containing protein 0.0407 0.0787 0.3381
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0495 0.1042 0.1399
Echinococcus granulosus c-Jun N-terminal kinases 0.0842 0.2042 0.2281
Echinococcus granulosus activated cdc42 kinase 1 0.0299 0.0474 0.0529
Echinococcus granulosus casein kinase I alpha 0.0306 0.0495 0.0553
Schistosoma mansoni serine/threonine protein kinase 0.065 0.1489 0.1489
Toxoplasma gondii aurora kinase 0.0461 0.0942 0.4173
Echinococcus multilocularis mitogen activated protein kinase 14 0.064 0.1459 0.1958
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0647 0.148 0.1987
Echinococcus granulosus mitogen activated protein kinase 3 0.0263 0.0371 0.0414
Entamoeba histolytica casein kinase, putative 0.0306 0.0495 0.2127
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.1003 0.1003
Brugia malayi serine/threonine-protein kinase 6 0.0461 0.0942 0.0942
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0219 0.0242 0.1072
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.026 0.0361 0.1661
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0318 0.0529 0.2468
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0219 0.0242 0.0982
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0262 0.0367 0.1624
Schistosoma mansoni tyrosine kinase 0.0308 0.0499 0.0499
Plasmodium vivax glycogen synthase kinase 3, putative 0.0407 0.0787 0.7489
Entamoeba histolytica cell division protein kinase 2, putative 0.0375 0.0695 0.2988
Schistosoma mansoni tyrosine kinase 0.1144 0.2914 0.2914
Echinococcus multilocularis N chimaerin 0.0229 0.0272 0.0365
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0215 0.0232 0.0998
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0266 0.0379 0.163
Brugia malayi MAP kinase sur-1 0.0263 0.0371 0.0371
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0522 0.112 0.125
Loa Loa (eye worm) TK protein kinase 0.0403 0.0775 0.0775
Echinococcus granulosus casein kinase I delta 0.0306 0.0495 0.0553
Onchocerca volvulus 0.0205 0.0203 0.0453
Schistosoma mansoni nck2/grb4 0.0186 0.0149 0.0149
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0248 0.0328 0.1353
Echinococcus granulosus serine/threonine protein kinase 0.052 0.1114 0.1244
Plasmodium falciparum glycogen synthase kinase 3 0.0407 0.0787 0.7489
Loa Loa (eye worm) hypothetical protein 0.0533 0.115 0.115
Echinococcus multilocularis protein kinase shaggy 0.0407 0.0787 0.1056
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0475 0.0984 0.0984
Echinococcus granulosus casein kinase I delta 0.0306 0.0495 0.0553
Loa Loa (eye worm) hypothetical protein 0.0299 0.0474 0.0474
Echinococcus multilocularis death associated protein kinase 1 0.2713 0.7449 1
Brugia malayi serine/threonine kinase 12 0.0461 0.0942 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0367 0.0367
Schistosoma mansoni protein kinase 0.0737 0.174 0.174
Entamoeba histolytica protein kinase domain containing protein 0.0219 0.0242 0.104
Echinococcus granulosus tyrosine protein kinase Src64B 0.0495 0.1042 0.1164
Schistosoma mansoni tyrosine kinase 0.1411 0.3686 0.3686
Loa Loa (eye worm) hypothetical protein 0.0243 0.0314 0.0314
Brugia malayi hypothetical protein 0.026 0.0361 0.0361
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0647 0.148 0.1653
Trypanosoma brucei cdc2-related kinase 3 0.0375 0.0695 0.2943
Schistosoma mansoni serine/threonine protein kinase 0.0595 0.1331 0.1331
Schistosoma mansoni unc-13 (munc13) 0.0139 0.0012 0.0012
Brugia malayi SRC-1 0.0495 0.1042 0.1042
Onchocerca volvulus 0.0215 0.0232 0.0521
Onchocerca volvulus Serine\/threonine kinase homolog 0.0861 0.2098 0.4931
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0242 0.0309 0.0309
Brugia malayi Protein kinase domain containing protein 0.0855 0.2081 0.2081
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Brugia malayi hypothetical protein 0.0215 0.0232 0.0232
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0368 0.0675 0.0675
Schistosoma mansoni serine/threonine protein kinase 0.052 0.1114 0.1114
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0139 0.0012 0.0016
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.027 0.0392 0.0526
Loa Loa (eye worm) hypothetical protein 0.0264 0.0373 0.0373
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.026 0.0361 0.0403
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Echinococcus granulosus TGF-beta receptor type-1 0.0177 0.0123 0.0137
Giardia lamblia Aurora kinase 0.0461 0.0942 0.4453
Brugia malayi Protein kinase domain containing protein 0.0215 0.0232 0.0232
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0316 0.0522 0.4923
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0497 0.1045 1
Plasmodium vivax protein kinase, putative 0.016 0.0072 0.055
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0612 0.138 0.138
Trichomonas vaginalis STE family protein kinase 0.027 0.0392 0.163
Echinococcus granulosus roundabout 2 0.0139 0.0012 0.0013
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0229 0.0272 0.0365
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Echinococcus granulosus cyclin dependent kinase 0.0375 0.0695 0.0777
Brugia malayi Protein kinase domain containing protein 0.1411 0.3686 0.3686
Brugia malayi P38 map kinase family protein 2 0.064 0.1459 0.1459
Schistosoma mansoni serine/threonine protein kinase 0.0842 0.2042 0.2042
Echinococcus multilocularis hypothetical protein 0.0287 0.0439 0.059
Brugia malayi map kinase activated protein kinase protein 2 0.1258 0.3245 0.3245
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0497 0.1045 1
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.3013 0.8315 0.8315
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0318 0.0529 0.0529
Schistosoma mansoni protein kinase 0.0316 0.0522 0.0522
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0266 0.0379 0.1749
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0263 0.0371 0.1538
Brugia malayi latrophilin 2 splice variant baaae 0.0243 0.0314 0.0314
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0393 0.0745 0.0745
Echinococcus multilocularis activated cdc42 kinase 1 0.0299 0.0474 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.0993 0.0993
Brugia malayi Tyrosine-protein kinase abl-1 0.0477 0.0988 0.0988
Schistosoma mansoni hypothetical protein 0.0243 0.0314 0.0314
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0917 0.2258 0.2258
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.027 0.0392 0.0438
Echinococcus granulosus mitogen activated protein kinase 14 0.064 0.1459 0.1629
Onchocerca volvulus 0.1037 0.2605 0.6131
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0482 0.1003 0.1003
Schistosoma mansoni vam6/vps39 related 0.026 0.0361 0.0361
Echinococcus granulosus protein kinase C gamma type 0.0651 0.1492 0.1667
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0164 0.0083 0.0083
Echinococcus granulosus roundabout 2 0.038 0.071 0.0793
Echinococcus granulosus unc 13 munc13 0.0139 0.0012 0.0013
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0222 0.0251 0.0337
Entamoeba histolytica protein kinase, putative 0.0917 0.2258 0.9706
Giardia lamblia Kinase, CAMK CAMKL 0.0257 0.0352 0.1619
Echinococcus granulosus dual specificity 0.0219 0.0242 0.027
Echinococcus multilocularis casein kinase I alpha 0.0306 0.0495 0.0664
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0267 0.1088
Schistosoma mansoni hypothetical protein 0.0287 0.0439 0.0439
Entamoeba histolytica protein kinase, putative 0.0222 0.0251 0.108
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0218 0.0239 0.0267
Echinococcus granulosus cyclin dependent kinase 7 0.0183 0.0139 0.0155
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0407 0.0787 0.0787
Schistosoma mansoni tyrosine kinase 0.1265 0.3264 0.3264
Brugia malayi Immunoglobulin I-set domain containing protein 0.0817 0.1972 0.1972
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0221 0.025 0.113
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0612 0.138 0.138
Onchocerca volvulus 0.0227 0.0267 0.0602
Loa Loa (eye worm) hypothetical protein 0.0264 0.0373 0.0373
Echinococcus granulosus tyrosine kinase 0.0403 0.0775 0.0866
Loa Loa (eye worm) hypothetical protein 0.0148 0.0038 0.0038
Plasmodium vivax tyrosine kinase-like protein, putative 0.0208 0.021 0.1894
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Loa Loa (eye worm) AGC/PKN protein kinase 0.0809 0.1949 0.1949
Brugia malayi Protein kinase domain containing protein 0.0612 0.138 0.138
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0229 0.0272 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0141 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0431 0.0856 0.3637
Loa Loa (eye worm) hypothetical protein 0.036 0.0652 0.0652
Brugia malayi Immunoglobulin I-set domain containing protein 0.0184 0.0141 0.0141
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0407 0.0787 0.0787
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0942 0.4011
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0638 0.1454 0.1951
Brugia malayi Protein kinase domain containing protein 0.057 0.1258 0.1258
Onchocerca volvulus 0.0149 0.004 0.0067
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0842 0.2042 0.2741
Schistosoma mansoni protein kinase 0.0198 0.0182 0.0182
Giardia lamblia Kinase, STE STE20 0.0266 0.0379 0.1749
Brugia malayi RhoGAP domain containing protein 0.0229 0.0272 0.0272
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1089 0.2757 0.2757
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0495 0.1042 0.1399
Entamoeba histolytica protein kinase domain containing protein 0.0221 0.025 0.1076
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Entamoeba histolytica protein kinase, putative 0.0266 0.0378 0.1626
Loa Loa (eye worm) hypothetical protein 0.0382 0.0713 0.0713
Echinococcus multilocularis unc 13 (munc13) 0.0139 0.0012 0.0016
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0208 0.021 0.0931
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0139 0.0012 0.0016
Brugia malayi Protein kinase domain containing protein 0.0166 0.009 0.009
Giardia lamblia Kinase, CMGC GSK 0.0407 0.0787 0.3705
Echinococcus granulosus cyclin dependent kinase 19 0.0241 0.0306 0.0342
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0367 0.1521
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0327 0.0555 0.0745
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0479 0.0993 0.1334
Echinococcus multilocularis TGF beta receptor type 1 0.0177 0.0123 0.0165
Onchocerca volvulus 0.0306 0.0495 0.1142
Brugia malayi Temporarily assigned gene name protein 59 0.026 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0262 0.0367 0.0367
Plasmodium falciparum NIMA related kinase 1 0.0431 0.0856 0.816
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0297 0.0469 0.0524
Brugia malayi Protein kinase domain containing protein 0.3013 0.8315 0.8315
Giardia lamblia Kinase, AGC PKA 0.0497 0.1045 0.4948
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0369 0.0678 0.2867
Loa Loa (eye worm) hypothetical protein 0.0248 0.0328 0.0328
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0482 0.1003 0.4745
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0529 0.0529
Echinococcus multilocularis serine:threonine protein kinase N2 0.0289 0.0446 0.0599
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0482 0.1003 0.4745
Echinococcus granulosus raf serine:threonine protein kinase 0.0256 0.035 0.039
Onchocerca volvulus 0.0184 0.0141 0.0306
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.027 0.0392 0.0438
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0177 0.0123 0.0165
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0224 0.0258 0.0347
Echinococcus multilocularis casein kinase I alpha 0.0306 0.0495 0.0664
Entamoeba histolytica protein kinase, putative 0.0222 0.0251 0.108
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0678 0.0678
Echinococcus multilocularis mitogen activated protein kinase 14 0.064 0.1459 0.1958
Loa Loa (eye worm) hypothetical protein 0.029 0.0449 0.0449
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0262 0.0367 0.0492
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Entamoeba histolytica protein kinase, putative 0.0194 0.0172 0.0741
Echinococcus granulosus tyrosine protein kinase Src42A 0.0495 0.1042 0.1164
Schistosoma mansoni tyrosine kinase 0.0215 0.0232 0.0232
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0212 0.0224 0.099
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0328 0.0328
Brugia malayi Stress-activated protein kinase jnk-1 0.0842 0.2042 0.2042
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0262 0.0367 0.0367
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0942 0.4011
Entamoeba histolytica protein kinase, putative 0.0262 0.0367 0.1576
Loa Loa (eye worm) AGC/PKA protein kinase 0.0318 0.0529 0.0529
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.0729 0.0729
Loa Loa (eye worm) hypothetical protein 0.0381 0.0712 0.0712
Echinococcus granulosus protein kinase 0.0368 0.0675 0.0754
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0375 0.0695 0.3267
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0737 0.174 0.1943
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0459 0.0936 0.1046
Entamoeba histolytica PH domain containing protein kinase, putative 0.052 0.1114 0.4787
Giardia lamblia Kinase, NEK 0.0431 0.0856 0.4038
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1129 0.2873 0.3208
Echinococcus granulosus growth factor receptor bound protein 2 0.0188 0.0154 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0139 0.0139
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Entamoeba histolytica tyrosin kinase, putative 0.0135 0.0002 0.0009
Echinococcus multilocularis insulin receptor 0.1411 0.3686 0.4948
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Schistosoma mansoni growth factor receptor-bound protein 0.0188 0.0154 0.0154
Schistosoma mansoni protein kinase 0.0737 0.174 0.174
Echinococcus multilocularis dual specificity 0.0219 0.0242 0.0325
Loa Loa (eye worm) hypothetical protein 0.0178 0.0124 0.0124
Echinococcus multilocularis twitchin 0.0161 0.0076 0.0103
Entamoeba histolytica casein kinase 1, putative 0.0306 0.0495 0.2127
Echinococcus multilocularis casein kinase I delta 0.0306 0.0495 0.0664
Echinococcus multilocularis c src tyrosine kinase 0.0308 0.0499 0.067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0139 0.0012 0.0012
Plasmodium falciparum protein serine/threonine kinase-1 0.0369 0.0678 0.6433
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0259 0.0359 0.0359
Loa Loa (eye worm) TK/ABL protein kinase 0.0658 0.1511 0.1511
Echinococcus granulosus neuroglian 0.0139 0.0012 0.0013
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0497 0.1045 0.1404
Echinococcus granulosus tyrosine protein kinase Fyn 0.0495 0.1042 0.1164
Echinococcus granulosus NCK adaptor protein 0.0186 0.0149 0.0167
Echinococcus granulosus casein kinase ii subunit alpha 0.0316 0.0522 0.0583
Echinococcus multilocularis serine:threonine protein kinase N2 0.0809 0.1949 0.2616
Brugia malayi Immunoglobulin I-set domain containing protein 0.0139 0.0012 0.0012
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0262 0.0367 0.041
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0221 0.025 0.113
Echinococcus granulosus serine:threonine kinase SAD 1 0.0248 0.0328 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Echinococcus granulosus cyclin dependent kinase 1 0.0375 0.0695 0.0777
Schistosoma mansoni vav2 0.0253 0.034 0.034
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Brugia malayi C1-like domain containing protein 0.0633 0.144 0.144
Brugia malayi serine/threonine-protein kinase PAK 7 0.0738 0.1744 0.1744
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Giardia lamblia Kinase, AGC AKT 0.037 0.0679 0.319
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0166 0.009 0.009
Echinococcus granulosus dual specificity 0.0219 0.0242 0.027
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0222 0.0251 0.0281
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0407 0.0787 0.0787
Loa Loa (eye worm) TK/EPH protein kinase 0.0382 0.0715 0.0715
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0318 0.0529 0.4989
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0318 0.0529 0.2468
Echinococcus multilocularis cyclin dependent kinase 9 0.0149 0.004 0.0054
Onchocerca volvulus Serine\/threonine kinase homolog 0.0393 0.0745 0.1734
Entamoeba histolytica casein kinase, putative 0.0316 0.0522 0.2245
Brugia malayi STE20-like kinase MST 0.0818 0.1973 0.1973
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0495 0.1042 0.1399
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0459 0.0936 0.1257
Brugia malayi hypothetical protein 0.0522 0.112 0.112
Echinococcus multilocularis calcium dependent protein kinase 0.0161 0.0077 0.0103
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0262 0.0367 0.041
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0212 0.0224 0.0224
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1258 0.3245 0.3624
Toxoplasma gondii AGC kinase 0.0318 0.0529 0.2343
Brugia malayi Fibronectin type III domain containing protein 0.0264 0.0373 0.0373
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0266 0.0379 0.1575
Loa Loa (eye worm) hypothetical protein 0.0205 0.0203 0.0203
Brugia malayi Protein kinase domain containing protein 0.0215 0.0232 0.0232
Onchocerca volvulus 0.0215 0.0232 0.0521
Echinococcus multilocularis serine threonine protein kinase 0.0651 0.1492 0.2003
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0263 0.0371 0.1708
Schistosoma mansoni protein kinase 0.0457 0.093 0.093
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0248 0.0328 0.1502
Trypanosoma brucei casein kinase I, isoform 2 0.0306 0.0495 0.2075
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0375 0.0695 0.0695
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0186 0.0149 0.0149
Schistosoma mansoni ephrin receptor 0.0326 0.0553 0.0553
Entamoeba histolytica protein kinase, putative 0.0225 0.0259 0.1115
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.036 0.0651 0.0874
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1258 0.3245 0.3245
Echinococcus multilocularis cyclin dependent kinase 7 0.0183 0.0139 0.0186
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0855 0.2081 0.2794
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Echinococcus multilocularis cyclin dependent kinase 1 0.0375 0.0695 0.0933
Trypanosoma brucei rac serine-threonine kinase, putative 0.094 0.2327 1
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0224 0.0258 0.0258
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0248 0.0328 0.1502
Echinococcus multilocularis serine:threonine protein kinase 0.036 0.0652 0.0875
Brugia malayi Protein kinase domain containing protein 0.1091 0.2761 0.2761
Leishmania major protein kinase, putative 0.0266 0.0379 0.1749
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0262 0.0367 0.1624
Echinococcus granulosus ephrin type A receptor 4 A 0.0326 0.0553 0.0618
Echinococcus granulosus cGMP dependent protein kinase 1 0.0327 0.0555 0.062
Schistosoma mansoni protein kinase 0.0737 0.174 0.174
Echinococcus granulosus rho-associated protein kinase 1 0.1037 0.2605 0.291
Echinococcus granulosus casein kinase I alpha 0.0306 0.0495 0.0553
Echinococcus granulosus calcium dependent protein kinase 0.0161 0.0077 0.0086
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0262 0.0367 0.3412
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0407 0.0787 0.3705
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0318 0.0529 0.2224
Brugia malayi Serine/threonine-protein kinase SULU 0.0522 0.112 0.112
Loa Loa (eye worm) TK/EGFR protein kinase 0.1932 0.5191 0.5191
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.036 0.0651 0.0727
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0306 0.0306
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0242 0.0309 0.0414
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0231 0.0279 0.0279
Brugia malayi hypothetical protein 0.0148 0.0038 0.0038
Giardia lamblia Kinase, PLK 0.0861 0.2098 1
Entamoeba histolytica protein kinase domain containing protein 0.0482 0.1003 0.4311
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0318 0.0529 0.2343
Plasmodium falciparum calcium-dependent protein kinase 4 0.0262 0.0367 0.3412
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Schistosoma mansoni serine/threonine protein kinase 0.0557 0.122 0.122
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.026 0.0361 0.0485
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1433 0.3751 0.4189
Brugia malayi Protein kinase domain containing protein 0.0215 0.0232 0.0232
Schistosoma mansoni tyrosine kinase 0.0756 0.1796 0.1796
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0262 0.0367 0.0367
Schistosoma mansoni protein kinase 0.0221 0.025 0.025
Echinococcus multilocularis cyclin dependent kinase 5 0.0375 0.0695 0.0933
Toxoplasma gondii NEK kinase 0.014 0.0015 0.0067
Leishmania major protein kinase, putative 0.0461 0.0942 0.4453
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Loa Loa (eye worm) IKK protein kinase 0.1091 0.2761 0.2761
Schistosoma mansoni serine/threonine protein kinase 0.0861 0.2098 0.2098
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0593 0.1325 0.1325
Schistosoma mansoni hypothetical protein 0.0287 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.0593 0.1325 0.1325
Brugia malayi Immunoglobulin I-set domain containing protein 0.184 0.4925 0.4925
Trichomonas vaginalis CAMK family protein kinase 0.0869 0.2122 0.9114
Echinococcus multilocularis raf serine:threonine protein kinase 0.0256 0.035 0.0469
Schistosoma mansoni tyrosine kinase 0.1144 0.2914 0.2914
Brugia malayi Pleckstrin Homology Domain 0.0158 0.0068 0.0068
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0371 0.1538
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0239 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0264 0.0373 0.0373
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0375 0.0695 0.0777
Brugia malayi protein-tyrosine kinase 0.0403 0.0775 0.0775
Giardia lamblia Kinase, STE STE20 0.027 0.0392 0.1809
Echinococcus granulosus Vam6:Vps39 protein 0.026 0.0361 0.0403
Schistosoma mansoni unc-13 (munc13) 0.0139 0.0012 0.0012
Echinococcus granulosus titin 0.0184 0.0141 0.0157
Trichomonas vaginalis AGC family protein kinase 0.0566 0.1245 0.5322
Echinococcus granulosus protein kinase shaggy 0.0407 0.0787 0.0879
Echinococcus granulosus serine:threonine protein kinase N2 0.0809 0.1949 0.2176
Loa Loa (eye worm) hypothetical protein 0.1451 0.3803 0.3803
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.026 0.0361 0.0361
Echinococcus granulosus Immunoglobulin 0.0242 0.0309 0.0345
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0327 0.0555 0.2459
Trichomonas vaginalis STE family protein kinase 0.0259 0.0359 0.149
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0363 0.066 0.066
Loa Loa (eye worm) AGC/NDR protein kinase 0.052 0.1114 0.1114
Echinococcus multilocularis roundabout 2 0.038 0.071 0.0953
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0756 0.1796 0.2006
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.017 0.0101 0.0374
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0638 0.1454 0.1624
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Trichomonas vaginalis CK1 family protein kinase 0.0306 0.0495 0.2075
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0557 0.122 0.122
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0283 0.043 0.0577
Brugia malayi Variant SH3 domain containing protein 0.0186 0.0149 0.0149
Echinococcus multilocularis casein kinase I delta 0.0306 0.0495 0.0664
Plasmodium vivax protein kinase Crk2 0.0375 0.0695 0.6602
Onchocerca volvulus 0.0227 0.0267 0.0602
Brugia malayi putative serine/threonine kinase SADA gamma 0.0248 0.0328 0.0328
Toxoplasma gondii histone kinase SNF1, putative 0.0248 0.0328 0.1451
Echinococcus multilocularis protein KINase family member (kin 25) 0.0189 0.0158 0.0212
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Onchocerca volvulus 0.0407 0.0787 0.1832
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0482 0.1003 0.4745
Schistosoma mansoni adapter molecule crk 0.0186 0.0149 0.0149
Trypanosoma brucei SNF1-related protein kinases, putative 0.0248 0.0328 0.1353
Onchocerca volvulus 0.026 0.0361 0.0826
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.0729 0.0729
Leishmania major protein kinase, putative 0.0262 0.0367 0.1688
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0248 0.0328 0.044
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.3234 0.8954 1
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.043 0.1793
Echinococcus granulosus serine:threonine protein kinase 3 0.0818 0.1973 0.2204
Schistosoma mansoni protein kinase 0.072 0.169 0.169
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0369 0.0678 0.3002
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0259 0.0359 0.1654
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0259 0.0359 0.149
Echinococcus granulosus mitogen activated protein kinase 11 0.064 0.1459 0.1629
Leishmania major protein kinase A catalytic subunit isoform 2 0.0318 0.0529 0.2468
Echinococcus multilocularis 0.0368 0.0675 0.0906
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1208 0.31 0.3462
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0861 0.2098 1
Brugia malayi serine/threonine protein kinase 6 0.0461 0.0942 0.0942
Echinococcus granulosus tyrosine protein kinase ABL1 0.0658 0.1511 0.1687
Entamoeba histolytica protein kinase, putative 0.0212 0.0224 0.0961
Schistosoma mansoni tyrosine kinase 0.0308 0.0499 0.0499
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0263 0.0371 0.0371
Leishmania major casein kinase, putative 0.0306 0.0495 0.2304
Brugia malayi Protein kinase domain containing protein 0.036 0.0652 0.0652
Entamoeba histolytica protein kinase, putative 0.027 0.0392 0.1684
Giardia lamblia Kinase, CMGC CLK 0.0369 0.0678 0.3183
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Schistosoma mansoni serine/threonine protein kinase 0.0461 0.0942 0.0942
Entamoeba histolytica protein kinase, putative 0.0309 0.0503 0.2163
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0229 0.0272 0.0272
Echinococcus multilocularis 0.0269 0.0388 0.0521
Brugia malayi Protein kinase c protein 2 0.0366 0.0669 0.0669
Brugia malayi Protein kinase domain containing protein 0.0369 0.0678 0.0678
Entamoeba histolytica hypothetical protein 0.0482 0.1003 0.4311
Plasmodium falciparum serine/threonine protein kinase, putative 0.0461 0.0942 0.8999
Brugia malayi cell division control protein 2 homolog 0.0375 0.0695 0.0695
Loa Loa (eye worm) hypothetical protein 0.026 0.0361 0.0361
Echinococcus multilocularis calcium activated potassium channel 0.0387 0.0729 0.0979
Brugia malayi Protein kinase domain containing protein 0.0227 0.0267 0.0267
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0369 0.0678 0.3183
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0861 0.2098 0.2343
Giardia lamblia Kinase, NEK 0.0431 0.0856 0.4038
Trypanosoma cruzi casein kinase II, putative 0.0316 0.0522 0.2436
Schistosoma mansoni cell adhesion molecule 0.0139 0.0012 0.0012
Schistosoma mansoni rap gtpase-activating protein 0.026 0.0361 0.0361
Echinococcus multilocularis tyrosine protein kinase HCK 0.0309 0.0503 0.0676
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0633 0.144 0.144
Echinococcus granulosus activated cdc42 kinase 1 0.0299 0.0474 0.0529
Trichomonas vaginalis STE family protein kinase 0.0201 0.0191 0.0761
Trypanosoma cruzi casein kinase, putative 0.0306 0.0495 0.2304
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.071
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1433 0.3751 0.5035
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0529 0.0529
Loa Loa (eye worm) AUR protein kinase 0.0461 0.0942 0.0942
Trichomonas vaginalis STE family protein kinase 0.027 0.0392 0.163
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0267 0.1088
Loa Loa (eye worm) hypothetical protein 0.0242 0.0309 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0647 0.148 0.148
Echinococcus multilocularis 0.0557 0.1218 0.1636
Leishmania major protein kinase A catalytic subunit 0.0318 0.0529 0.2468
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0369 0.0678 0.3183
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Loa Loa (eye worm) hypothetical protein 0.026 0.0361 0.0361
Echinococcus granulosus dual specificity 0.0219 0.0242 0.027
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0263 0.0371 0.1708
Trypanosoma cruzi cdc2-related kinase 3 0.0375 0.0695 0.3267
Echinococcus granulosus titin 0.0184 0.0141 0.0157
Brugia malayi Egg laying defective protein 4 0.0327 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.0358 0.0645 0.0645
Giardia lamblia Kinase, CDC7 0.0227 0.0267 0.1208
Schistosoma mansoni tyrosine kinase 0.0222 0.0251 0.0251
Brugia malayi Fes/CIP4 homology domain containing protein 0.0252 0.034 0.034
Schistosoma mansoni nephrin 0.0139 0.0012 0.0012
Schistosoma mansoni protein kinase 0.072 0.169 0.169
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.0495 0.0495
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0318 0.0529 0.2224
Echinococcus granulosus serine:threonine protein kinase N2 0.0289 0.0446 0.0498
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.035 0.035
Giardia lamblia Kinase, CMGC MAPK 0.0263 0.0371 0.1708
Onchocerca volvulus 0.0215 0.0232 0.0521
Mycobacterium ulcerans hypothetical protein 0.0227 0.0265 0.5
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0238 0.0298 0.0298
Plasmodium falciparum serine/threonine protein kinase 0.0212 0.0224 0.2024
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0183 0.0139 0.0139
Trichomonas vaginalis STE family protein kinase 0.0431 0.0856 0.3637
Giardia lamblia Kinase, CMGC CDK 0.0375 0.0695 0.3267
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.004 0.004
Brugia malayi Protein kinase domain 0.027 0.0392 0.0392
Entamoeba histolytica protein kinase, putative 0.0482 0.1003 0.4311
Echinococcus multilocularis serine:threonine protein kinase 38 0.052 0.1114 0.1495
Entamoeba histolytica protein kinase, putative 0.052 0.1114 0.4786
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0633 0.144 0.144
Echinococcus multilocularis serine:threonine protein kinase N2 0.052 0.1114 0.1495
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0382 0.0713 0.0713
Echinococcus multilocularis dual specificity protein kinase clk2 0.0369 0.0678 0.091
Echinococcus granulosus nervana 2 0.0396 0.0756 0.0844
Brugia malayi intracellular kinase 0.0407 0.0787 0.0787
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0238 0.0298 0.0298
Entamoeba histolytica protein kinase, putative 0.0212 0.0224 0.0961
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0318 0.0529 0.2468
Echinococcus multilocularis protein kinase c epsilon type 0.0659 0.1515 0.2033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0737 0.174 0.2336
Schistosoma mansoni serine/threonine protein kinase 0.079 0.1892 0.1892
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0375 0.0695 0.0695
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0262 0.0367 0.3412
Echinococcus granulosus Protein kinase C brain isozyme 0.0786 0.1882 0.2102
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Brugia malayi ribosomal protein S6 kinase alpha 3 0.037 0.0679 0.0679
Echinococcus granulosus mitogen activated protein kinase 0.0263 0.0371 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.0139 0.0012 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.035 0.035
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0942 0.4011
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0855 0.2081 0.2081
Trichomonas vaginalis CMGC family protein kinase 0.0316 0.0522 0.2194
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1258 0.3245 0.4356
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0522 0.112 0.1503
Brugia malayi Hr1 repeat family protein 0.0809 0.1949 0.1949
Trypanosoma cruzi cdc2-related kinase 1 0.0375 0.0695 0.3267
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0878 0.2146 0.2397
Entamoeba histolytica serine/threonine protein kinase, putative 0.0248 0.0328 0.1409
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0461 0.0942 0.405
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0431 0.0856 0.816
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0241 0.0306 0.0306
Echinococcus multilocularis nervana 2 0.0396 0.0756 0.1014
Brugia malayi SH2 domain containing protein 0.0215 0.0232 0.0232
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0461 0.0942 0.1052
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0308 0.0499 0.0499
Schistosoma mansoni serine/threonine protein kinase 0.3596 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0222 0.0251 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.057 0.1258 0.5377
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0139 0.0012 0.0012
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0266 0.0379 0.1749
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0229 0.0272 0.0303
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0224 0.0258 0.0288
Echinococcus multilocularis casein kinase I gamma 0.0299 0.0474 0.0636
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0522 0.112 0.112
Echinococcus multilocularis tyrosine protein kinase Srms 0.0403 0.0775 0.104
Echinococcus granulosus NDR protein kinase 0.052 0.1114 0.1244
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0786 0.1882 0.2526
Plasmodium falciparum calcium-dependent protein kinase 5 0.0262 0.0367 0.3412
Entamoeba histolytica p21-activated kinase 0.0294 0.046 0.1978
Loa Loa (eye worm) hypothetical protein 0.0139 0.0012 0.0012
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0146 0.0032 0.0075
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0756 0.1796 0.2411
Loa Loa (eye worm) hypothetical protein 0.0358 0.0645 0.0645
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0266 0.0379 0.163
Trypanosoma cruzi casein kinase, putative 0.0306 0.0495 0.2304
Loa Loa (eye worm) hypothetical protein 0.0148 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.1365 0.3553 0.3553
Brugia malayi Protein kinase domain containing protein 0.0566 0.1245 0.1245
Brugia malayi ephrin receptor 1 precursor 0.0218 0.024 0.024
Plasmodium falciparum serine/threonine protein kinase KIN 0.0248 0.0328 0.3035
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0218 0.0239 0.0321
Toxoplasma gondii CMGC kinase, CK2 family 0.0316 0.0522 0.2313
Trichomonas vaginalis AGC family protein kinase 0.0256 0.035 0.1448
Echinococcus granulosus twitchin 0.0403 0.0774 0.0865
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0221 0.025 0.1108
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0495 0.1042 0.1399
Brugia malayi Protein kinase domain containing protein 0.094 0.2327 0.2327
Loa Loa (eye worm) AUR protein kinase 0.0461 0.0942 0.0942
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0497 0.1045 0.1168
Echinococcus multilocularis tyrosine kinase 0.0215 0.0232 0.0312
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.026 0.0361 0.0361
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.052 0.1114 0.1495
Loa Loa (eye worm) hypothetical protein 0.046 0.094 0.094
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0529 0.0529
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0263 0.0371 0.1708
Schistosoma mansoni titin 0.0184 0.0141 0.0141
Entamoeba histolytica PH domain containing protein kinase, putative 0.052 0.1114 0.4787
Brugia malayi Protein kinase domain containing protein 0.0241 0.0306 0.0306
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.027 0.0392 0.0526
Entamoeba histolytica serine/threonine protein kinase, putative 0.0861 0.2098 0.9014
Echinococcus granulosus protein tyrosine kinase 0.125 0.322 0.3597
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0166 0.009 0.009
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1027 0.2577 0.2577
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0659 0.1515 0.1515
Trypanosoma cruzi polo-like protein kinase, putative 0.0861 0.2098 1
Trichomonas vaginalis AGC family protein kinase 0.0566 0.1245 0.5322
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0215 0.0232 0.0312
Loa Loa (eye worm) TK protein kinase 0.0817 0.1972 0.1972
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.079 0.1892 0.2113
Echinococcus multilocularis myosin iiia 0.0266 0.0379 0.0509
Brugia malayi Protein kinase domain containing protein 0.0393 0.0745 0.0745
Brugia malayi Protein kinase domain containing protein 0.0581 0.1289 0.1289
Brugia malayi hypothetical protein 0.0264 0.0373 0.0373
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.052 0.1114 0.1495
Brugia malayi Protein kinase domain containing protein 0.0212 0.0224 0.0224
Echinococcus multilocularis expressed protein 0.0212 0.0224 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0861 0.2098 0.2098
Onchocerca volvulus Tyrosine kinase homolog 0.1603 0.4242 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1265 0.3264 0.3645
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0369 0.0678 0.3183
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0328 0.0328
Echinococcus granulosus tyrosine protein kinase Src42A 0.0284 0.043 0.0481
Schistosoma mansoni protein kinase 0.0461 0.0942 0.0942
Echinococcus multilocularis CDC7 cell division cycle 7 0.0227 0.0267 0.0358
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0566 0.1245 0.1245
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0139 0.0012 0.0016
Onchocerca volvulus 0.0533 0.115 0.2691
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0461 0.0942 0.405
Echinococcus multilocularis tyrosine protein kinase shark 0.0215 0.0232 0.0312
Plasmodium vivax casein kinase 1, putative 0.0306 0.0495 0.4656
Schistosoma mansoni serine/threonine protein kinase 0.0659 0.1515 0.1515
Schistosoma mansoni tyrosine kinase 0.1932 0.5191 0.5191
Echinococcus granulosus Glutaredoxin protein 5 0.0396 0.0756 0.0844
Loa Loa (eye worm) hypothetical protein 0.0297 0.0469 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0371 0.0371
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0164 0.0083 0.0112
Entamoeba histolytica serine/threonine protein kinase, putative 0.014 0.0015 0.0065
Schistosoma mansoni neuroglian 0.0139 0.0012 0.0012
Brugia malayi Protein kinase domain containing protein 0.0946 0.2343 0.2343
Echinococcus granulosus serine:threonine protein kinase 0.036 0.0652 0.0728
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Brugia malayi Protein kinase domain containing protein 0.0457 0.093 0.093
Loa Loa (eye worm) SRC-1 0.0495 0.1042 0.1042
Schistosoma mansoni protein kinase 0.0306 0.0495 0.0495
Leishmania major casein kinase II, putative 0.0316 0.0522 0.2436
Trypanosoma cruzi cdc2-related kinase 1 0.0375 0.0695 0.3267
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0306 0.0495 0.0495
Loa Loa (eye worm) hypothetical protein 0.0318 0.0529 0.0529
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0396 0.0756 0.1014
Echinococcus multilocularis neuroglian 0.0302 0.0484 0.065
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1365 0.3553 0.3553
Trichomonas vaginalis CMGC family protein kinase 0.0375 0.0695 0.2943
Toxoplasma gondii AGC kinase 0.0318 0.0529 0.2343
Giardia lamblia Kinase, CMGC DYRK 0.0219 0.0242 0.109
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0163 0.0082 0.0092
Schistosoma mansoni ste20-related kinase 0.0652 0.1495 0.1495
Entamoeba histolytica protein kinase, putative 0.0219 0.0242 0.104
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.052 0.1114 0.1244
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0555 0.0555
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0495 0.1042 0.1399
Loa Loa (eye worm) TK/ROR protein kinase 0.0182 0.0136 0.0136
Trypanosoma brucei protein kinase, putative 0.0407 0.0787 0.3338
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0224 0.0258 0.0258
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0647 0.148 0.1653
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0407 0.0787 0.3483
Loa Loa (eye worm) hypothetical protein 0.0556 0.1218 0.1218
Echinococcus multilocularis Immunoglobulin 0.0242 0.0309 0.0414
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0189 0.0158 0.0176
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.0591
Loa Loa (eye worm) hypothetical protein 0.0728 0.1714 0.1714
Toxoplasma gondii NEK kinase 0.014 0.0015 0.0067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0495 0.1042 0.1164
Entamoeba histolytica hypothetical protein 0.0847 0.2059 0.8847
Echinococcus granulosus tyrosine protein kinase shark 0.0215 0.0232 0.0259
Echinococcus granulosus dual specificity protein kinase clk2 0.0369 0.0678 0.0757
Entamoeba histolytica protein kinase, putative 0.0225 0.0259 0.1115
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0369 0.0678 0.3183
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Onchocerca volvulus 0.0556 0.1218 0.2852
Echinococcus granulosus cGMP dependent protein kinase 0.0327 0.0555 0.062
Brugia malayi Protein kinase domain containing protein 0.1263 0.3259 0.3259
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0262 0.0367 0.3412
Brugia malayi Protein kinase domain containing protein 0.0375 0.0695 0.0695
Loa Loa (eye worm) TK/INSR protein kinase 0.1411 0.3686 0.3686
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0818 0.1973 0.1973
Loa Loa (eye worm) hypothetical protein 0.0593 0.1325 0.1325
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1451 0.3803 0.3803
Schistosoma mansoni protein kinase 0.0259 0.0359 0.0359
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0479 0.0993 0.0993
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0479 0.0993 0.4269
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0242 0.0309 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0786 0.1882 0.1882
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.052 0.1114 0.1244
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0198 0.0182 0.0182
Echinococcus granulosus serine:threonine protein kinase 0.036 0.0652 0.0728
Trichomonas vaginalis CMGC family protein kinase 0.0375 0.0695 0.2943
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0369 0.0678 0.2867
Brugia malayi protein kinase C3,putative 0.0501 0.1057 0.1057
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.071
Loa Loa (eye worm) TK/FAK protein kinase 0.1263 0.3259 0.3259
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0318 0.0529 0.2224
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0257 0.0352 0.3272
Echinococcus multilocularis dual specificity testis specific protein kinase 0.072 0.169 0.2268
Schistosoma mansoni serine/threonine-protein kinase 0.052 0.1114 0.1114
Trichomonas vaginalis STE family protein kinase 0.0259 0.0359 0.149
Trypanosoma brucei cdc2-related kinase 1 0.0375 0.0695 0.2943
Trichomonas vaginalis AGC family protein kinase 0.0529 0.1138 0.4858
Loa Loa (eye worm) hypothetical protein 0.0189 0.0158 0.0158
Onchocerca volvulus 0.0398 0.0761 0.177
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0221 0.025 0.1018
Brugia malayi Protein kinase domain containing protein 0.1365 0.3553 0.3553
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0263 0.0371 0.1708
Echinococcus multilocularis cyclin dependent kinase 1 0.0375 0.0695 0.0933
Brugia malayi Variant SH3 domain containing protein 0.0186 0.0149 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0224 0.0224
Brugia malayi protein kinase C II. 0.0659 0.1515 0.1515
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0219 0.0242 0.0242
Schistosoma mansoni vesicular amine transporter 0.0242 0.0309 0.0309
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0259 0.0359 0.0359
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0139 0.0012 0.0013
Trichomonas vaginalis CK1 family protein kinase 0.0306 0.0495 0.2075
Plasmodium vivax serine/threonine kinase-1, putative 0.0369 0.0678 0.6433
Echinococcus multilocularis cyclin dependent kinase 0.0375 0.0695 0.0933
Brugia malayi Protein kinase domain containing protein 0.0215 0.0232 0.0232
Echinococcus multilocularis roundabout 2 0.0139 0.0012 0.0016
Brugia malayi Protein kinase domain containing protein 0.052 0.1114 0.1114
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1129 0.2873 0.3856
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus granulosus neuroglian 0.0302 0.0484 0.0541
Echinococcus granulosus casein kinase i 0.0306 0.0495 0.0553
Plasmodium vivax calcium-dependent protein kinase, putative 0.0262 0.0367 0.3412
Echinococcus granulosus cyclin dependent kinase 5 0.0375 0.0695 0.0777
Loa Loa (eye worm) hypothetical protein 0.0398 0.0761 0.0761
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus multilocularis casein kinase i 0.0306 0.0495 0.0664
Brugia malayi phosphoinositide-dependent protein kinase I 0.0256 0.035 0.035
Brugia malayi Variant SH3 domain containing protein 0.0229 0.0272 0.0272
Plasmodium falciparum calcium-dependent protein kinase 3 0.0262 0.0367 0.3412
Entamoeba histolytica protein kinase, putative 0.094 0.2327 1
Schistosoma mansoni tyrosine kinase 0.1265 0.3264 0.3264
Trichomonas vaginalis AGC family protein kinase 0.0256 0.035 0.1448
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0878 0.2146 0.2881
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Onchocerca volvulus 0.0215 0.0232 0.0521
Echinococcus multilocularis expressed conserved protein 0.0327 0.0555 0.0745
Schistosoma mansoni serine/threonine kinase 0.052 0.1114 0.1114
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Trichomonas vaginalis CAMK family protein kinase 0.04 0.0765 0.3246
Echinococcus granulosus aurora kinase A 0.0461 0.0942 0.1052
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Loa Loa (eye worm) AGC/PKG protein kinase 0.0327 0.0555 0.0555
Brugia malayi probable protein kinase 0.0628 0.1425 0.1425
Schistosoma mansoni serine/threonine protein kinase 0.0786 0.1882 0.1882
Schistosoma mansoni tyrosine kinase 0.125 0.322 0.322
Trypanosoma brucei aurora B kinase 0.0461 0.0942 0.4011
Entamoeba histolytica protein kinase domain containing protein 0.0407 0.0787 0.3381
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0861 0.2098 0.2816
Echinococcus multilocularis nervana 2 0.0396 0.0756 0.1014
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0393 0.0745 0.0832
Entamoeba histolytica protein kinase, putative 0.094 0.2327 1
Schistosoma mansoni protein kinase 0.0628 0.1425 0.1425
Echinococcus multilocularis NCK adaptor protein 0.0188 0.0154 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.036 0.0652 0.2755
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus multilocularis dual specificity 0.0219 0.0242 0.0325
Schistosoma mansoni protein kinase C mu 0.0633 0.144 0.144
Echinococcus multilocularis ephrin type A receptor 4 A 0.0326 0.0553 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0139 0.0139
Echinococcus granulosus cyclin dependent kinase 9 0.0157 0.0065 0.0072
Onchocerca volvulus 0.0215 0.0232 0.0521
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Brugia malayi protein unc-22 0.0184 0.0141 0.0141
Brugia malayi Protein kinase domain containing protein 0.0256 0.035 0.035
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0842 0.2042 0.2042
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0262 0.0367 0.0367
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0262 0.0367 0.0492
Loa Loa (eye worm) AGC/AKT protein kinase 0.094 0.2327 0.2327
Loa Loa (eye worm) TK/KIN16 protein kinase 0.184 0.4925 0.4925
Brugia malayi cyclin-dependent kinase 9 0.0149 0.004 0.004
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0647 0.148 0.1987
Schistosoma mansoni protein kinase 0.0177 0.0123 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0407 0.0787 0.3338
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Plasmodium vivax serine/threonine protein kinase, putative 0.0212 0.0224 0.2024
Loa Loa (eye worm) hypothetical protein 0.0242 0.0309 0.0309
Trichomonas vaginalis STE family protein kinase 0.027 0.0392 0.163
Brugia malayi Protein kinase domain containing protein 0.0164 0.0083 0.0083
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0403 0.0775 0.104
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0482 0.1003 0.4274
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0403 0.0775 0.0866
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0263 0.0371 0.1641
Loa Loa (eye worm) hypothetical protein 0.0398 0.0761 0.0761
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0407 0.0787 0.3705
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0396 0.0756 0.0844
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0612 0.138 0.1541
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0219 0.0242 0.0242
Brugia malayi Cam kinase protein 1 0.0262 0.0367 0.0367
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.0591
Echinococcus multilocularis Immunoglobulin 0.0242 0.0309 0.0414
Toxoplasma gondii AGC kinase 0.0917 0.2258 1
Echinococcus multilocularis neuroglian 0.0139 0.0012 0.0016
Echinococcus multilocularis myotubularin protein 13 0.0158 0.0068 0.0092
Echinococcus granulosus c src tyrosine kinase 0.0308 0.0499 0.0557
Entamoeba histolytica protein kinase, putative 0.0407 0.0787 0.3381
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0371 0.1538
Brugia malayi Tyrosine-protein kinase abl-1 0.0273 0.0401 0.0401
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0256 0.035 0.0391
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0407 0.0787 0.1056
Echinococcus multilocularis cyclin dependent kinase 19 0.0241 0.0306 0.0411
Brugia malayi p70 ribosomal S6 kinase beta 0.0917 0.2258 0.2258
Loa Loa (eye worm) TK protein kinase 0.0309 0.0503 0.0503
Trichomonas vaginalis AGC family protein kinase 0.094 0.2327 1
Echinococcus granulosus CDC7 cell division cycle 7 0.0227 0.0267 0.0298
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0248 0.0328 0.1502
Echinococcus granulosus roundabout 2 0.0139 0.0012 0.0013
Schistosoma mansoni protein kinase 0.027 0.0392 0.0392
Echinococcus granulosus TGF beta receptor type 1 0.0177 0.0123 0.0137
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.064 0.1459 0.6245
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0248 0.0328 0.1502
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0242 0.0311 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.0678 0.0678
Giardia lamblia Kinase, CMGC GSK 0.0407 0.0787 0.3705
Loa Loa (eye worm) hypothetical protein 0.017 0.0102 0.0102
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0394 0.0748 0.3518
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0756 0.1796 0.2411
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.036 0.0652 0.0652
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.017 0.0101 0.0101
Plasmodium falciparum casein kinase 1 0.0306 0.0495 0.4656
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0186 0.0149 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.0393 0.0745 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0251 0.0251
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0139 0.0012 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0612 0.138 0.138
Echinococcus multilocularis dual specificity 0.0482 0.1003 0.1347
Onchocerca volvulus 0.1091 0.2761 0.65
Echinococcus granulosus protein kinase c iota type 0.0921 0.227 0.2536
Onchocerca volvulus 0.0215 0.0232 0.0521
Schistosoma mansoni serine/threonine kinase 0.0579 0.1283 0.1283
Schistosoma mansoni hypothetical protein 0.026 0.0361 0.0361
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0431 0.0856 0.379
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0248 0.0328 0.1353
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0557 0.122 0.1638
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Trypanosoma cruzi rac serine-threonine kinase, putative 0.052 0.1114 0.5277
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0101 0.0101
Schistosoma mansoni nephrin 0.0325 0.0549 0.0549
Brugia malayi Protein kinase domain containing protein 0.0215 0.0232 0.0232
Brugia malayi bone morphogenetic protein type 1 receptor 0.0198 0.0182 0.0182
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.043 0.1793
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0298 0.0298
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1365 0.3553 0.3553
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.064 0.1459 0.6932
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Echinococcus granulosus dual specificity 0.0482 0.1003 0.112
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0375 0.0695 0.0695
Brugia malayi cyclin-dependent kinase 7 homolog 0.0191 0.0163 0.0163
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Echinococcus granulosus activin receptor type 0.0614 0.1384 0.1546
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0212 0.0224 0.1002
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0102 0.0376
Trypanosoma brucei polo-like protein kinase 0.0861 0.2098 0.9008
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0306 0.0495 0.2304
Loa Loa (eye worm) hypothetical protein 0.1114 0.2827 0.2827
Loa Loa (eye worm) hypothetical protein 0.0215 0.0232 0.0232
Echinococcus multilocularis mitogen activated protein kinase 0.0263 0.0371 0.0498
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0184 0.0141 0.0141
Echinococcus multilocularis PAK box P21 Rho binding 0.0201 0.0191 0.0256
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.017 0.0101 0.0415
Echinococcus granulosus cyclin dependent kinase 9 0.0149 0.004 0.0045
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0612 0.138 0.3235
Echinococcus granulosus serine threonine protein kinase nrc 0.0497 0.1045 0.1168
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0032 0.0075
Entamoeba histolytica protein kinase , putative 0.0461 0.0942 0.405
Entamoeba histolytica protein kinase, putative 0.0201 0.0191 0.0821
Schistosoma mansoni protein kinase 0.0368 0.0675 0.0675
Loa Loa (eye worm) hypothetical protein 0.0139 0.0012 0.0012
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0495 0.1042 0.1164
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.064 0.1459 0.6932
Echinococcus multilocularis roundabout 2 0.0139 0.0012 0.0016
Schistosoma mansoni ephrin receptor 0.0143 0.0025 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0371 0.1538
Brugia malayi Protein kinase domain containing protein 0.0616 0.1391 0.1391
Echinococcus granulosus tyrosine protein kinase Blk 0.0403 0.0775 0.0866
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0139 0.0012 0.0016
Leishmania major protein kinase, putative 0.0221 0.025 0.113
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0186 0.0149 0.0149
Loa Loa (eye worm) CAMK protein kinase 0.0184 0.0141 0.0141
Loa Loa (eye worm) TK/FER protein kinase 0.0215 0.0232 0.0232
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0212 0.0224 0.1002
Brugia malayi casein kinase I 0.0306 0.0495 0.0495
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0076 0.0076
Echinococcus multilocularis casein kinase I alpha 0.0306 0.0495 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0647 0.148 0.148
Echinococcus granulosus tyrosine kinase 0.0215 0.0232 0.0259
Loa Loa (eye worm) hypothetical protein 0.026 0.0361 0.0361
Schistosoma mansoni tyrosine kinase 0.1411 0.3686 0.3686
Echinococcus granulosus cGMP dependent protein kinase 1 0.0327 0.0555 0.062
Trypanosoma cruzi Protein kinase B 0.052 0.1114 0.5277
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0557 0.122 0.122
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0318 0.0529 0.2468
Schistosoma mansoni serine/threonine protein kinase 0.1037 0.2605 0.2605
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.071
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.017 0.0101 0.0371
Schistosoma mansoni tyrosine kinase 0.0495 0.1042 0.1042
Schistosoma mansoni growth factor receptor-bound protein 0.0186 0.0149 0.0149
Schistosoma mansoni tyrosine kinase 0.0787 0.1884 0.1884
Onchocerca volvulus 0.0199 0.0186 0.0413
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0658 0.1511 0.2028
Loa Loa (eye worm) protein kinase domain-containing protein 0.0299 0.0474 0.0474
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0318 0.0529 0.071
Trichomonas vaginalis STE family protein kinase 0.0259 0.0359 0.149
Onchocerca volvulus 0.0936 0.2315 0.5446
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.0729 0.0729
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.064 0.1459 0.1459
Brugia malayi SH2 domain containing protein 0.0215 0.0232 0.0232
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0612 0.138 0.138
Brugia malayi Kinase associated domain 1 family protein 0.0287 0.0439 0.0439
Brugia malayi Protein kinase domain containing protein 0.0482 0.1003 0.1003
Trichomonas vaginalis CAMK family protein kinase 0.0861 0.2098 0.9008
Schistosoma mansoni tyrosine kinase 0.0189 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0186 0.0149 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0695 0.0695
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0375 0.0695 0.3079
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0242 0.0982
Onchocerca volvulus 0.0206 0.0205 0.0457
Entamoeba histolytica protein kinase, putative 0.0461 0.0942 0.405
Trypanosoma brucei Casein kinase II 0.0316 0.0522 0.2194
Plasmodium vivax unspecified product 0.0316 0.0522 0.4923
Echinococcus multilocularis protein kinase c iota type 0.0921 0.227 0.3048
Echinococcus multilocularis transfer RNA-Thr 0.0299 0.0474 0.0636
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0262 0.0367 0.0492
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.004 0.0173
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0327 0.0555 0.0745
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0002 0.0009
Echinococcus granulosus casein kinase I alpha 0.0306 0.0495 0.0553
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.026 0.0361 0.1496
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.079 0.1892 0.254
Brugia malayi Calcitonin receptor-like protein seb-1 0.0356 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.0269 0.0388 0.0388
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0528 0.1135 0.1268
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0495 0.1042 0.1399
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0465 0.0955 0.4067
Brugia malayi Protein kinase domain containing protein 0.0299 0.0474 0.0474
Schistosoma mansoni atypical protein kinase C 0.094 0.2327 0.2327
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0146 0.0032 0.0075
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0224 0.0258 0.0258
Echinococcus granulosus tyrosine protein kinase Lyn 0.0596 0.1332 0.1488
Loa Loa (eye worm) hypothetical protein 0.1029 0.2583 0.2583
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0598 0.2568
Echinococcus granulosus dual specificity testis-specific protein kinase 0.072 0.169 0.1887
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0242 0.0242
Echinococcus granulosus N chimaerin 0.0229 0.0272 0.0303
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0612 0.138 0.1853
Echinococcus multilocularis rho associated protein kinase 0.1037 0.2605 0.3498
Schistosoma mansoni serine/threonine protein kinase 0.065 0.1489 0.1489
Trypanosoma cruzi polo-like protein kinase, putative 0.0861 0.2098 1
Schistosoma mansoni tyrosine kinase 0.1144 0.2914 0.2914
Trichomonas vaginalis AGC family protein kinase 0.017 0.0101 0.0371
Schistosoma mansoni kinase 0.092 0.2268 0.2268
Echinococcus granulosus nervana 2 0.0396 0.0756 0.0844
Plasmodium falciparum protein kinase 5 0.0375 0.0695 0.6602
Echinococcus granulosus epidermal growth factor receptor 0.1932 0.5191 0.5798
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0555 0.0555
Echinococcus granulosus expressed protein 0.0212 0.0224 0.025
Echinococcus granulosus tyrosine protein kinase Fyn 0.0495 0.1042 0.1164
Echinococcus multilocularis epidermal growth factor receptor 0.1265 0.3264 0.4382

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 152 nM Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand ChEMBL. 12729661
Ki (binding) = 152 nM Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand ChEMBL. 12729661
Ki (functional) = 152 nM Antagonist activity at human histamine H3 receptor ChEMBL. 21937153

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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