Detailed information for compound 784108

Basic information

Technical information
  • TDR Targets ID: 784108
  • Name: 2-[(4-chlorophenyl)methylsulfanyl]-N-[(3-meth oxyphenyl)methylideneamino]acetamide
  • MW: 348.847 | Formula: C17H17ClN2O2S
  • H donors: 1 H acceptors: 1 LogP: 3.95 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)C=NNC(=O)CSCc1ccc(cc1)Cl
  • InChi: 1S/C17H17ClN2O2S/c1-22-16-4-2-3-14(9-16)10-19-20-17(21)12-23-11-13-5-7-15(18)8-6-13/h2-10H,11-12H2,1H3,(H,20,21)/b19-10+
  • InChiKey: WPRITNOXQIMJGT-VXLYETTFSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-chlorophenyl)methylsulfanyl]-N-[(3-methoxyphenyl)methyleneamino]acetamide
  • 2-[(4-chlorophenyl)methylthio]-N-[(3-methoxyphenyl)methyleneamino]acetamide
  • 2-[(4-chlorobenzyl)thio]-N-[(3-methoxybenzylidene)amino]acetamide
  • 2-[(4-chlorophenyl)methylsulfanyl]-N-[(3-methoxyphenyl)methylideneamino]ethanamide
  • A0651/0030269
  • (4-Chloro-benzylsulfanyl)-acetic acid (3-methoxy-benzylidene)-hydrazide
  • BAS 00288446

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved protein 0.0477 0.1509 0.1441
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0127 0.0235
Echinococcus granulosus high affinity choline transporter 1 0.019 0.0562 0.104
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.0096 0.0177
Brugia malayi hypothetical protein 0.0088 0.0223 0.0606
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0219 0.0405
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0291 0.0894 0.2642
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0096 0.0177
Leishmania major fatty acid transporter protein-like protein 0.1036 0.3359 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.008
Loa Loa (eye worm) hypothetical protein 0.0193 0.057 0.1384
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0452 0.2644
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0154 0.1016
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0088 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0701 0.1297
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Loa Loa (eye worm) Smad1 0.0033 0.0042 0.0101
Plasmodium vivax importin-beta 2, putative 0.0119 0.0326 0.2118
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0127 0.0346
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0152 0.0182
Schistosoma mansoni hypothetical protein 0.0193 0.057 0.1055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0096 0.0178
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0278 0.0513
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.001 0.0017
Mycobacterium ulcerans hypothetical protein 0.0477 0.1509 0.408
Echinococcus multilocularis lamin dm0 0.0028 0.0026 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Brugia malayi lysyl-tRNA synthetase 0.0023 0.001 0.0026
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0087 0.021
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0099 0.026 0.068
Schistosoma mansoni smad1 5 8 and 0.0033 0.0042 0.0077
Brugia malayi hypothetical protein 0.0232 0.0701 0.1902
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0275 0.1605
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.0278 0.0753
Giardia lamblia PHD finger protein 15 0.0059 0.0128 0.2687
Schistosoma mansoni hypothetical protein 0.1539 0.5022 0.9295
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0126 0.0349 0.0847
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0034 0.0044 0.0112
Mycobacterium tuberculosis Probable hydrolase 0.0477 0.1509 0.1441
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0471 0.1489 0.404
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0036 0.0097
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0219 0.0626
Echinococcus multilocularis mitogen activated protein kinase 0.0157 0.0452 0.0543
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0036 0.0066
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0099 0.026 0.0745
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0477 0.1509 0.1441
Leishmania major glucose transporter, lmgt1 0.0032 0.0039 0.0094
Onchocerca volvulus 0.0042 0.0072 0.0477
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0295 0.1723
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0026 0.0062
Treponema pallidum NADH oxidase 0.0044 0.0079 0.2093
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0104 0.0278 0.0513
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0157 0.0452 0.296
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Brugia malayi tailless protein 0.0049 0.0096 0.026
Giardia lamblia Kinase, CMGC MAPK 0.0157 0.0452 1
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0032 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0477 0.1509 0.4422
Plasmodium falciparum phd finger protein, putative 0.0059 0.0128 0.0876
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0279
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0044 0.0118
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0177 0.052 0.0444
Brugia malayi latrophilin 2 splice variant baaae 0.0416 0.131 0.3554
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0062
Brugia malayi MAP kinase sur-1 0.0157 0.0452 0.1227
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.026 0.1224
Schistosoma mansoni kinase 0.0053 0.0108 0.0199
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0471 0.1489 0.1787
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.0121 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.0104 0.0278 0.0333
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0219 0.1409
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0044 0.0079 0.0478
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0044 0.024
Onchocerca volvulus 0.0032 0.004 0.0264
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0099 0.0259 0.0181
Brugia malayi Probable ClpP-like protease 0.0086 0.0219 0.0594
Onchocerca volvulus 0.0042 0.0072 0.0477
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0404
Echinococcus granulosus General substrate transporter 0.0089 0.0227 0.0419
Brugia malayi TAR-binding protein 0.0126 0.0349 0.0948
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0096 0.026
Loa Loa (eye worm) hypothetical protein 0.0047 0.0088 0.0212
Chlamydia trachomatis pyruvate kinase 0.0067 0.0154 0.687
Trypanosoma brucei pyruvate kinase 1 0.0067 0.0154 0.0972
Trichomonas vaginalis D-aminoacylase, putative 0.0477 0.1509 0.8827
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Echinococcus granulosus intermediate filament protein 0.0028 0.0026 0.0047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0099 0.0259 0.1824
Mycobacterium tuberculosis Probable dehydrogenase 0.0291 0.0894 0.0822
Brugia malayi Latrophilin receptor protein 2 0.0193 0.057 0.1548
Echinococcus multilocularis thioredoxin glutathione reductase 0.0129 0.0358 0.043
Echinococcus multilocularis snurportin 1 0.1267 0.4121 0.4948
Brugia malayi nuclear receptor NHR-88 0.0104 0.0278 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Schistosoma mansoni smad1 5 8 and 0.0033 0.0042 0.0077
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0068 0.0181
Echinococcus granulosus smad 0.0033 0.0042 0.0077
Echinococcus granulosus solute carrier family 5 0.019 0.0562 0.104
Schistosoma mansoni lipoxygenase 0.0117 0.0322 0.0595
Trichomonas vaginalis glucosylceramidase, putative 0.0371 0.1162 0.6794
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0099 0.026 0.068
Trichomonas vaginalis penicillin-binding protein, putative 0.0477 0.1509 0.8827
Brugia malayi mbt repeat family protein 0.0047 0.0088 0.0237
Leishmania major pyruvate kinase 0.0067 0.0154 0.0435
Echinococcus granulosus expressed conserved protein 0.0096 0.025 0.0463
Onchocerca volvulus Huntingtin homolog 0.0126 0.0351 0.2324
Loa Loa (eye worm) thioredoxin reductase 0.0127 0.0355 0.086
Schistosoma mansoni terminal deoxycytidyl transferase 0.0059 0.0127 0.0235
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.019 0.0562 0.104
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0295 0.1723
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0099 0.026 0.0747
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0044
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0044 0.0261
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0099 0.026 0.0752
Loa Loa (eye worm) glutathione reductase 0.0127 0.0355 0.086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Echinococcus granulosus mitogen activated protein kinase 0.0157 0.0452 0.0836
Echinococcus multilocularis ecdysone induced protein 78C 0.0104 0.0278 0.0333
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0072 0.0175
Schistosoma mansoni glucose transport protein 0.0103 0.0275 0.0508
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.014 0.0356
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0044 0.0079 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0349 0.0646
Giardia lamblia DINP protein human, muc B family 0.0059 0.0127 0.2663
Brugia malayi Cam kinase protein 1 0.0033 0.0044 0.0118
Echinococcus granulosus ecdysone induced protein 78C 0.0104 0.0278 0.0513
Brugia malayi hypothetical protein 0.0055 0.0115 0.0313
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0053 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0039 0.0096
Echinococcus multilocularis pyruvate kinase 0.0067 0.0154 0.0184
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0326 0.2118
Onchocerca volvulus 0.0111 0.0299 0.1981
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0191 0.0354
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.0154 0.0075
Brugia malayi PHD-finger family protein 0.0026 0.0019 0.0052
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 0.057
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0157 0.0452 0.1326
Echinococcus granulosus dna polymerase eta 0.0059 0.0127 0.0235
Trichomonas vaginalis glutaminase, putative 0.0534 0.17 0.9943
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0471 0.1489 0.2756
Entamoeba histolytica protein kinase, putative 0.0033 0.0044 0.0204
Loa Loa (eye worm) hypothetical protein 0.0416 0.131 0.3178
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Schistosoma mansoni cpg binding protein 0.0123 0.0339 0.0628
Echinococcus multilocularis cpg binding protein 0.0123 0.0339 0.0407
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.004 0.0074
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0701 0.0841
Brugia malayi Pre-SET motif family protein 0.0032 0.004 0.0109
Leishmania major acetyl-CoA synthetase, putative 0.0099 0.026 0.0752
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0107
Leishmania major pyruvate kinase 0.0067 0.0154 0.0435
Schistosoma mansoni ap endonuclease 0.0099 0.0259 0.0479
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0094 0.0629
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0186 0.053
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0 0.0001
Echinococcus granulosus cpg binding protein 0.0123 0.0339 0.0628
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0036 0.0592
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0099 0.0259 0.1675
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0167 0.0308
Trypanosoma cruzi trypanothione reductase, putative 0.0127 0.0355 0.1025
Schistosoma mansoni high-affinity choline transporter 0.019 0.0562 0.104
Brugia malayi MH2 domain containing protein 0.0033 0.0042 0.0113
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0044 0.0261
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0044 0.0079 0.0521
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Echinococcus multilocularis GPCR, family 2 0.0193 0.057 0.0685
Brugia malayi nuclear receptor RXR 0.0055 0.0115 0.0313
Echinococcus multilocularis lysosomal alpha glucosidase 0.0492 0.1562 0.1875
Echinococcus granulosus tumor protein p63 0.033 0.1023 0.1893
Brugia malayi photoreceptor-specific nuclear receptor 0.0104 0.0278 0.0753
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.0096 0.0115
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0128 0.0237
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0152 0.0427
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0094 0.0256
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.004 0.0074
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.004 0.0048
Mycobacterium ulcerans glutaminase 0.0534 0.17 0.4599
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.0052
Mycobacterium ulcerans acetyl-CoA synthetase 0.0099 0.026 0.068
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0072 0.0133
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.0266 0.0721
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.0266 0.0644
Loa Loa (eye worm) steroid hormone receptor 0.0104 0.0278 0.0673
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.0931 0.6148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0026 0.002 0.0081
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.0096 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0471 0.1489 0.2756
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.0121 0.0145
Brugia malayi Importin beta-1 subunit 0.0119 0.0326 0.0884
Loa Loa (eye worm) hypothetical protein 0.0053 0.0109 0.0264
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Schistosoma mansoni cpg binding protein 0.0123 0.0339 0.0628
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0152 0.0959
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0104 0.0278 0.0673
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0193 0.057 0.0685
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 0.8238
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Echinococcus granulosus dna polymerase kappa 0.0059 0.0127 0.0235
Echinococcus granulosus lamin dm0 0.0028 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0099 0.026 0.0629
Leishmania major acetyl-CoA synthetase, putative 0.0099 0.026 0.0752
Onchocerca volvulus 0.0099 0.026 0.1719
Leishmania major trypanothione reductase 0.0127 0.0355 0.1036
Schistosoma mansoni transcription factor LCR-F1 0.0661 0.2119 0.3922
Echinococcus granulosus snurportin 1 0.1267 0.4121 0.7627
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.0052
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0152 0.0959
Trypanosoma brucei unspecified product 0.004 0.0067 0.0397
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0094 0.0113
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0036 0.0078
Schistosoma mansoni protein kinase 0.0033 0.0044 0.008
Trichomonas vaginalis ran, putative 0.0066 0.0152 0.0886
Loa Loa (eye worm) hypothetical protein 0.0067 0.0154 0.0372
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.0205 0.0246
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0044 0.0105
Brugia malayi ecdysone receptor 0.0049 0.0096 0.026
Loa Loa (eye worm) transcription factor SMAD2 0.0481 0.1524 0.3697
Schistosoma mansoni nuclear receptor 0.0049 0.0096 0.0177
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0056 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Brugia malayi ecdysteroid receptor 0.0104 0.0278 0.0753
Schistosoma mansoni acetyl-CoA synthetase 0.0099 0.026 0.048
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0099 0.0259 0.0751
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0094 0.0113
Onchocerca volvulus 0.0477 0.1509 1
Brugia malayi Bromodomain containing protein 0.0066 0.0152 0.0413
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0053 0.03
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.009 0.0244
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0186 0.1297
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0031 0.0037
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0085 0.0214 0.0136
Plasmodium vivax pyruvate kinase, putative 0.0067 0.0154 0.0972
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.014 0.0396
Schistosoma mansoni smad1 5 8 and 0.0033 0.0042 0.0077
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.0931 0.272
Toxoplasma gondii hypothetical protein 0.0049 0.0094 0.0577
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.0018 0.0022
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0477 0.1509 0.1441
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0094 0.0259
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0104 0.0278 0.0513
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0295 0.139
Toxoplasma gondii ABC1 family protein 0.0477 0.1509 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0094 0.0578
Brugia malayi glutaminase DH11.1 0.0534 0.17 0.4612
Echinococcus granulosus Niemann Pick C1 protein 0.0146 0.0416 0.0769
Brugia malayi MH1 domain containing protein 0.0033 0.0042 0.0113
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0026 0.007
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0099 0.026 0.068
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0099 0.026 0.068
Mycobacterium tuberculosis Probable lipase LipD 0.0477 0.1509 0.1441
Trichomonas vaginalis penicillin-binding protein, putative 0.0477 0.1509 0.8827
Echinococcus multilocularis Niemann Pick C1 protein 0.0146 0.0416 0.0499
Echinococcus multilocularis protein dispatched 1 0.005 0.0099 0.0118
Mycobacterium ulcerans beta-lactamase 0.0477 0.1509 0.408
Brugia malayi beta-lactamase family protein 0.0477 0.1509 0.4095
Loa Loa (eye worm) hypothetical protein 0.0126 0.0351 0.0851
Echinococcus multilocularis sodium:myo inositol cotransporter 0.019 0.0562 0.0674
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0044 0.0254
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0492 0.1562 0.3789
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0099 0.026 0.048
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0115 0.0313
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0115 0.0313
Echinococcus multilocularis pyruvate kinase 0.0034 0.0046 0.0055
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.022 0.1414
Brugia malayi Carboxylesterase family protein 0.0071 0.0167 0.0453
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0086
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0322 0.0386
Loa Loa (eye worm) hypothetical protein 0.0046 0.0087 0.021
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0109 0.0295 0.0715
Loa Loa (eye worm) hypothetical protein 0.019 0.0562 0.1363
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0152 0.321
Loa Loa (eye worm) sugar transporter 0.0103 0.0275 0.0666
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Schistosoma mansoni pyruvate kinase 0.0067 0.0154 0.0284
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0471 0.1489 0.3613
Brugia malayi Steroid receptor seven-up type 2 0.0104 0.0278 0.0753
Brugia malayi follicle stimulating hormone receptor 0.047 0.1488 0.4037
Onchocerca volvulus 0.0104 0.0278 0.1838
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0021 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.014 0.0061
Brugia malayi jmjC domain containing protein 0.0078 0.0191 0.0519
Echinococcus multilocularis neuropeptide receptor A26 0.0925 0.299 0.359
Schistosoma mansoni jumonji domain containing protein 0.0154 0.0441 0.0816
Brugia malayi RNA recognition motif domain containing protein 0.0126 0.0349 0.0948
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.0096 0.0177
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0104 0.0278 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0053 0.0135
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0627 0.152
Trypanosoma cruzi hypothetical protein, conserved 0.0477 0.1509 0.4422
Schistosoma mansoni rab6-interacting 0.0042 0.0072 0.0133
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0127 0.0798
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0068 0.0397
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Echinococcus multilocularis translational activator gcn1 0.0022 0.0008 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0278 0.0333
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0088 0.0105
Onchocerca volvulus Protein ultraspiracle homolog 0.0104 0.0278 0.1838
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Trichomonas vaginalis antibiotic synthetase, putative 0.0099 0.026 0.1518
Schistosoma mansoni polycystin 1-related 0.0042 0.0072 0.0133
Giardia lamblia Kinase, PLK 0.0101 0.0266 0.5788
Brugia malayi beta-lactamase family protein 0.0477 0.1509 0.4095
Brugia malayi steroid hormone receptor 0.0104 0.0278 0.0753
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.026 0.0752
Brugia malayi RNA binding protein 0.0126 0.0349 0.0948
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0072 0.0133
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Echinococcus granulosus jumonji domain containing protein 0.0082 0.0205 0.0379
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0452 0.1311
Echinococcus granulosus lysosomal alpha glucosidase 0.0492 0.1562 0.289
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.1489 0.2756
Loa Loa (eye worm) CXXC zinc finger family protein 0.0116 0.0317 0.077
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0266 0.0763
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0079 0.0215
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.014 0.0168
Trichomonas vaginalis sucrase-isomaltase, putative 0.0109 0.0295 0.1723
Brugia malayi beta-lactamase 0.0477 0.1509 0.4095
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0018 0.0034
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0747
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.0121 0.0332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0104 0.0278 0.0673
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0099 0.0259 0.0479
Mycobacterium ulcerans pyruvate kinase 0.0067 0.0154 0.0392
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0326 0.2118
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.026 0.0752
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0094 0.0228
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0104 0.0278 0.0333
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0036 0.0097
Onchocerca volvulus 0.0028 0.0026 0.0169
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0053 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0349 0.0646
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0039 0.0228
Echinococcus multilocularis expressed conserved protein 0.0096 0.025 0.03
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0193 0.0572 0.1059
Brugia malayi nuclear hormone receptor 0.0104 0.0278 0.0753
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0477 0.1509 0.3661
Loa Loa (eye worm) glutaminase 2 0.0534 0.17 0.4124
Toxoplasma gondii protein kinase, putative 0.0293 0.0903 0.5963
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.0096 0.0177
Echinococcus multilocularis tar DNA binding protein 0.0126 0.0349 0.0419
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Echinococcus multilocularis sodium:glucose cotransporter 2 0.019 0.0562 0.0674
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0291 0.0894 0.0822
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.014 0.0259
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Schistosoma mansoni inositol transporter 0.019 0.0562 0.104
Echinococcus multilocularis pyruvate kinase 0.0034 0.0046 0.0055
Echinococcus multilocularis neuropeptide s receptor 0.0925 0.299 0.359
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0405 0.1174
Loa Loa (eye worm) jmjC domain-containing protein 0.0122 0.0336 0.0815
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0053 0.03
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0405 0.265
Loa Loa (eye worm) glutaminase 0.0534 0.17 0.4124
Echinococcus granulosus sodium:glucose cotransporter 0.019 0.0562 0.104
Loa Loa (eye worm) hypothetical protein 0.0099 0.026 0.0629
Onchocerca volvulus 0.0285 0.0875 0.5798
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 0.057
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.008
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0036 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0041 0.0068 0.0181
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0661 0.2119 0.3922
Entamoeba histolytica hypothetical protein 0.0661 0.2119 1
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0177 0.052 0.1388
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0068 0.0397
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 0.7772
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Toxoplasma gondii NADPH-glutathione reductase 0.0044 0.0079 0.0478
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0177 0.052 0.1388
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0157 0.0452 0.1311
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0154 0.0372
Echinococcus multilocularis tumor protein p63 0.033 0.1023 0.1228
Trichomonas vaginalis ap endonuclease, putative 0.0099 0.0259 0.1515
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.0278 0.0513
Mycobacterium ulcerans hypothetical protein 0.0099 0.026 0.068
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0055 0.0115 0.0138
Mycobacterium tuberculosis Probable lipase LipE 0.0477 0.1509 0.1441
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.0096 0.0177
Loa Loa (eye worm) hypothetical protein 0.0101 0.0268 0.0649
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0127 0.0356
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0096 0.0633
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0099 0.026 0.0182
Loa Loa (eye worm) hypothetical protein 0.0232 0.0701 0.17
Echinococcus multilocularis importin 5 0.0022 0.0008 0.0009
Leishmania major glycosyl hydrolase-like protein 0.0041 0.0068 0.018
Echinococcus granulosus long chain fatty acid transport protein 4 0.105 0.3404 0.6301
Leishmania major protein kinase, putative 0.0033 0.0044 0.0107
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.004 0.0074
Echinococcus granulosus acetylcholinesterase 0.0071 0.0167 0.0308
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0078 0.0094
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0099 0.026 0.068
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0128 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0072 0.0086
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.1489 0.2756
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0477 0.1509 0.4095
Leishmania major hypothetical protein, conserved 0.0477 0.1509 0.448
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0079 0.0478
Loa Loa (eye worm) hypothetical protein 0.0077 0.0186 0.0452
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0088 0.0162
Entamoeba histolytica hypothetical protein 0.0661 0.2119 1
Echinococcus granulosus tar DNA binding protein 0.0126 0.0349 0.0646
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0169 0.0203
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0508
Echinococcus granulosus translational activator gcn1 0.0022 0.0008 0.0014
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0219 0.0263
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0032 0.0176
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.0266 0.176
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0128 0.0311
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0219 0.0405
Schistosoma mansoni glutaminase 0.0534 0.17 0.3146
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Leishmania major GTP-binding protein, putative 0.0066 0.0152 0.043
Echinococcus multilocularis protein patched 0.0044 0.0078 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0036 0.0066
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0099 0.026 0.068
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0104 0.0278 0.0333
Schistosoma mansoni coup transcription factor 0.0104 0.0278 0.0513
Schistosoma mansoni hypothetical protein 0.0042 0.0073 0.0135
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0099 0.026 0.068
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0032 0.006
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0109 0.013
Brugia malayi exodeoxyribonuclease III family protein 0.0099 0.0259 0.0703
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0044 0.024
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0042 0.0101
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0104 0.0288
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 0.1533
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0042 0.0077
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0099 0.026 0.0311
Trypanosoma brucei glucose transporter 1E 0.0032 0.0039 0.0211
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0154 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0196 0.4214
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0127 0.0153
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0452 0.2644
Trypanosoma brucei unspecified product 0.004 0.0067 0.0397
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0094 0.0113
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.002 0.0118
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0154 0.1016
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0099 0.026 0.0182
Schistosoma mansoni nuclear receptor 0.0049 0.0096 0.0177
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0093 0.0172
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0104 0.0278 0.0513
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0349 0.0646
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0099 0.0259 0.0743
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0096 0.0633
Brugia malayi jmjC domain containing protein 0.0193 0.0572 0.1553
Leishmania major hypothetical protein, conserved 0.0077 0.0186 0.0534
Onchocerca volvulus 0.0028 0.0026 0.0169
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0128 0.0805
Onchocerca volvulus 0.0099 0.026 0.1719
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0099 0.0259 0.1222
Brugia malayi Glycosyl hydrolases family 31 protein 0.0492 0.1562 0.4237
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0096 0.0115
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0196 0.1366
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0099 0.026 0.1224
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0056 0.0067
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0087 0.0409
Onchocerca volvulus 0.0238 0.0721 0.4779
Mycobacterium tuberculosis Probable reductase 0.0291 0.0894 0.0822
Schistosoma mansoni rab6-interacting 0.0042 0.0072 0.0133
Mycobacterium tuberculosis Probable esterase LipL 0.0477 0.1509 0.1441
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.0096 0.026
Entamoeba histolytica protein kinase, putative 0.0033 0.0044 0.0204
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0 0.0001
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.001 0.0055
Brugia malayi PHD-finger family protein 0.0059 0.0128 0.0349
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0295 0.0908 0.168
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.026 0.0752
Brugia malayi Sugar transporter family protein 0.0103 0.0275 0.0745
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0039 0.0096
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.026 0.1224
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0323 0.1002 0.2962
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0044 0.0079 0.0095
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0072 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0039 0.0228
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0104 0.0278 0.0513
Echinococcus multilocularis dna polymerase eta 0.0059 0.0127 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0104 0.0605
Loa Loa (eye worm) hypothetical protein 0.0099 0.026 0.0629
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0127 0.0356
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0044 0.0079 0.0478
Schistosoma mansoni hypothetical protein 0.0193 0.057 0.1055
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0094 0.0259
Plasmodium vivax glutathione reductase, putative 0.0127 0.0355 0.2312
Plasmodium vivax thioredoxin reductase, putative 0.0127 0.0355 0.2312
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0349 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0452 0.0836
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.001 0.0017
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0157 0.0452 0.1311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0104 0.0278 0.0673
Toxoplasma gondii HEAT repeat-containing protein 0.0119 0.0326 0.2118
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Plasmodium falciparum glutathione reductase 0.0044 0.0079 0.0521
Echinococcus multilocularis high affinity choline transporter 1 0.019 0.0562 0.0674
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0191 0.0354
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0537 0.171 0.4639
Echinococcus granulosus RUN 0.0042 0.0072 0.0133
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0279
Brugia malayi MH1 domain containing protein 0.0033 0.0042 0.0113
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0128 0.0805
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0349 0.0646
Echinococcus granulosus pyruvate kinase 0.0034 0.0046 0.0085
Loa Loa (eye worm) hypothetical protein 0.0086 0.0219 0.0531
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.049 0.3215
Brugia malayi hypothetical protein 0.0042 0.0072 0.0196
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0059 0.0127 0.0235
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0099 0.026 0.1678
Echinococcus granulosus lysine specific demethylase 5A 0.0078 0.0191 0.0354
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0079 0.0478
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.0096 0.026
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0165 0.048 0.1165
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0127 0.0798
Echinococcus multilocularis transportin 1 0.0022 0.0008 0.0009
Onchocerca volvulus 0.0477 0.1509 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0099 0.026 0.0182
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0152 0.028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0072 0.0175
Brugia malayi hypothetical protein 0.0126 0.0351 0.0952
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.0271 0.0735
Loa Loa (eye worm) hypothetical protein 0.0042 0.0072 0.0175
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0154 0.0433
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.0266 0.0491
Giardia lamblia Pyruvate kinase 0.0067 0.0154 0.3253
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0154 0.0372
Plasmodium falciparum protein kinase 6 0.044 0.1387 1
Loa Loa (eye worm) DR-78 0.0049 0.0096 0.0232
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.0271 0.0325
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0039 0.0228
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0219 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0094 0.0578
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0096 0.0115
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.1539 0.5022 0.9295
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.004 0.0048
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0078 0.0144
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1135 0.3685 0.8942
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0068 0.0397
Loa Loa (eye worm) kap beta 3 protein 0.0022 0.0008 0.0018
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0154 0.0433
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0096 0.0177
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0323 0.1002 0.093
Echinococcus multilocularis neutral alpha glucosidase AB 0.0109 0.0295 0.0354
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0152 0.0427
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0099 0.026 0.1678
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0104 0.0278 0.0753
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.0096 0.026
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.0931 0.272
Echinococcus granulosus pyruvate kinase 0.0067 0.0154 0.0284
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0099 0.026 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0039 0.0228
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0088 0.0579
Loa Loa (eye worm) MBCTL1 0.0053 0.0109 0.0264
Echinococcus granulosus neuropeptide receptor A26 0.0925 0.299 0.5535
Schistosoma mansoni pyruvate kinase 0.0067 0.0154 0.0284
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0276 0.0511
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0096 0.026
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.022 0.1414
Schistosoma mansoni eyes absent homolog 0.0088 0.0223 0.0413
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0096 0.0177
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0094 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0154 0.0372
Toxoplasma gondii propionate-CoA ligase 0.0099 0.026 0.1678
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0127 0.0356
Leishmania major alpha glucosidase II subunit, putative 0.0109 0.0295 0.0857
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0214
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0452 0.2644
Echinococcus granulosus histone acetyltransferase KAT2B 0.0286 0.088 0.1629
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.008
Schistosoma mansoni DNA polymerase eta 0.0059 0.0127 0.0235
Schistosoma mansoni glucose transport protein 0.0103 0.0275 0.0508
Echinococcus multilocularis pyruvate kinase 0.0034 0.0046 0.0055
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0609 0.1947 0.4723
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0044 0.024
Schistosoma mansoni protein kinase 0.0033 0.0044 0.008
Brugia malayi nuclear receptor NHR-67 0.0049 0.0096 0.026
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0099 0.026 0.0629
Loa Loa (eye worm) oxidoreductase 0.0099 0.026 0.0629
Onchocerca volvulus 0.0049 0.0096 0.0633
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.0096 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0109 0.0201
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.0018 0.0033
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0059 0.0127 0.0153
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0039 0.0096
Schistosoma mansoni Smad4 0.0033 0.0042 0.0077
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0186 0.1191
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0104 0.0278 0.0753
Brugia malayi Calcitonin receptor-like protein seb-1 0.0609 0.1947 0.5282
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0036 0.0168
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0109 0.0295 0.139
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0042 0.0077
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0477 0.1509 0.1441
Onchocerca volvulus Huntingtin homolog 0.0126 0.0351 0.2324
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0039 0.0228
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0152 0.0959
Schistosoma mansoni hypothetical protein 0.0303 0.0936 0.1732
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0295 0.1723
Echinococcus granulosus carboxylesterase 5A 0.0071 0.0167 0.0308
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0104 0.0278 0.0513
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Toxoplasma gondii hypothetical protein 0.003 0.0032 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0186 0.1297
Echinococcus granulosus pyruvate kinase 0.0034 0.0046 0.0085
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0032 0.0039
Onchocerca volvulus 0.0099 0.026 0.1719
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0104 0.0278 0.0333
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0279
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0047 0.0086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0044 0.0261
Loa Loa (eye worm) latrophilin receptor protein 2 0.0193 0.057 0.1384
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0291 0.0894 0.0822
Brugia malayi hypothetical protein 0.0077 0.0186 0.0506
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0322 0.0595
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0329
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0477 0.1509 0.408
Plasmodium vivax hypothetical protein, conserved 0.0477 0.1509 1
Schistosoma mansoni hypothetical protein 0.1267 0.4121 0.7627
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Brugia malayi Glycosyl hydrolases family 31 protein 0.0109 0.0295 0.08
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0167 0.02
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Mycobacterium leprae Probable lipase LipE 0.0477 0.1509 0.4477
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0278 0.0333
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0104 0.0278 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0397
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0046 0.0281
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0295 0.1723
Brugia malayi Doublecortin family protein 0.0042 0.0072 0.0196
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0026 0.0062
Echinococcus multilocularis dnaJ subfamily B 0.1654 0.5403 0.6487
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0046 0.0258
Onchocerca volvulus 0.019 0.0562 0.3722
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Loa Loa (eye worm) hypothetical protein 0.0048 0.0093 0.0225
Trypanosoma brucei polo-like protein kinase 0.0101 0.0266 0.1719
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Brugia malayi RNA, U transporter 1 0.0337 0.1049 0.2846
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0044 0.024
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0109 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0295 0.0848
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0278 0.0513
Echinococcus granulosus geminin 0.1539 0.5022 0.9295
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.0052
Entamoeba histolytica hypothetical protein 0.0096 0.0251 0.1186
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.001 0.0013
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0044 0.0079 0.019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0105
Giardia lamblia Pyruvate kinase 0.0034 0.0046 0.0832
Echinococcus multilocularis pyruvate kinase 0.0067 0.0154 0.0184
Plasmodium vivax CDK-related protein kinase 6, putative 0.044 0.1387 0.9187
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0266 0.0763
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0031 0.0058
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0323 0.1002 0.093
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Schistosoma mansoni ran 0.0066 0.0152 0.028
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0044 0.0239
Plasmodium falciparum hexose transporter 0.0103 0.0275 0.1935
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0044 0.0079 0.0521
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.014 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0266 0.0491
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0215
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.0096 0.0232
Mycobacterium ulcerans esterase/lipase LipP 0.0477 0.1509 0.408
Schistosoma mansoni hypothetical protein 0.0416 0.131 0.2424
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0609 0.1947 0.5282
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.001 0.0013
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0088 0.0162
Toxoplasma gondii histone lysine methyltransferase SET1 0.0228 0.0688 0.4535
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.014 0.0356
Mycobacterium tuberculosis Conserved protein 0.0477 0.1509 0.1441
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0295 0.0848
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0099 0.0259 0.0679
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0275 0.0329
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.0096 0.0115
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0088 0.0162
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0404
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0127 0.0355 0.0278
Onchocerca volvulus 0.0048 0.0093 0.0614
Plasmodium vivax SET domain protein, putative 0.0032 0.004 0.0216
Trichomonas vaginalis maltase-glucoamylase, putative 0.0109 0.0295 0.1723
Brugia malayi Thioredoxin reductase 0.0127 0.0355 0.0963
Brugia malayi hypothetical protein 0.0049 0.0096 0.026
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0109 0.013
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.0096 0.0177
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0152 0.1044
Brugia malayi GH02984p 0.019 0.0562 0.1525
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0044 0.0079 0.019
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Loa Loa (eye worm) hypothetical protein 0.019 0.0562 0.1363
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0079 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0104 0.0278 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0104 0.0605
Onchocerca volvulus Bile acid receptor homolog 0.0104 0.0278 0.1838
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0177 0.052 0.1529
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.004 0.0074
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.0154 0.0417
Toxoplasma gondii exonuclease III APE 0.0099 0.0259 0.1675
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Echinococcus multilocularis carboxylesterase 5A 0.0071 0.0167 0.02
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0032 0.0041 0.011
Giardia lamblia NADH oxidase lateral transfer candidate 0.0044 0.0079 0.1578
Echinococcus multilocularis pyruvate kinase 0.0053 0.0107 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0109 0.0295
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0044 0.0079 0.0214
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0039 0.0094
Echinococcus multilocularis musashi 0.0028 0.0026 0.0031
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0018 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0068 0.0397
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0032 0.0041 0.011
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0044 0.024
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0295 0.0908 0.109
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.0266 0.1253
Mycobacterium tuberculosis Probable oxidoreductase 0.0323 0.1002 0.093
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.0096 0.026
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0099 0.0259 0.564
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0099 0.026 0.0182
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Brugia malayi mbt repeat family protein 0.0047 0.0088 0.0237
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0127 0.0744
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0044 0.024
Trypanosoma brucei protein kinase, putative 0.0157 0.0452 0.296
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0508
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.022 0.1286
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0096 0.0177
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.0278 0.0753
Trichomonas vaginalis mercuric reductase, putative 0.0044 0.0079 0.0464
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0452 0.1311
Echinococcus granulosus Smad4 0.0033 0.0042 0.0077
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0154 0.0897
Onchocerca volvulus Alhambra homolog 0.0059 0.0128 0.085
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0036 0.0066
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0127 0.0798
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0099 0.026 0.068
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0104 0.0278 0.0513
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0128 0.0154
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0099 0.026 0.1678
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0118 0.032
Onchocerca volvulus 0.0116 0.0317 0.2102
Trypanosoma brucei glucose transporter 2A 0.0032 0.0039 0.0211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1036 0.3359 0.3306
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0079 0.0215
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0042 0.0101
Brugia malayi MH2 domain containing protein 0.0033 0.0042 0.0113
Schistosoma mansoni hypothetical protein 0.0059 0.0128 0.0237
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0152 0.0367
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0104 0.0278 0.0513
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0044 0.0105
Brugia malayi Sodium:solute symporter family protein 0.019 0.0562 0.1525
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0094 0.0578
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0247 0.0752 0.1391
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0044 0.0079 0.0147
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0193 0.057 0.1055
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0177 0.052 0.0624
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.0154 0.0417
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Echinococcus multilocularis lysosomal alpha glucosidase 0.0492 0.1562 0.1875
Onchocerca volvulus Glucosylceramidase homolog 0.0353 0.1099 0.7281
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0059 0.0127 0.0309
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.004 0.0074
Schistosoma mansoni protein kinase 0.0033 0.0044 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.014 0.0356
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0088 0.0212
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0044 0.024
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0032 0.006
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0072 0.0468
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0109 0.0201
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0094 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Plasmodium vivax acetyl-CoA synthetase, putative 0.0099 0.026 0.1678
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.0278 0.0753
Trichomonas vaginalis antibiotic synthetase, putative 0.0099 0.026 0.1518
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0028 0.0051
Loa Loa (eye worm) MH2 domain-containing protein 0.0481 0.1524 0.3697
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0018 0.005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0291 0.0894 0.0822
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0072 0.0133
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0291 0.0894 0.0822
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0044 0.0261
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0094 0.0578
Schistosoma mansoni hypothetical protein 0.0042 0.0073 0.0135
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0127 0.0798
Trichomonas vaginalis set domain proteins, putative 0.0238 0.0721 0.4219
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0204 0.0606 0.0728
Echinococcus multilocularis General substrate transporter 0.0089 0.0227 0.0272
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0186 0.1191
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.022 0.1286
Trichomonas vaginalis ap endonuclease, putative 0.0099 0.0259 0.1515
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0032 0.0161
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.0121 0.0042
Leishmania major pantothenate kinase subunit, putative 0.0034 0.0044 0.011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0189
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0099 0.026 0.0745
Brugia malayi hypothetical protein 0.002 0 0.0001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.0271 0.1277
Brugia malayi acetyltransferase, GNAT family protein 0.0295 0.0908 0.2463
Entamoeba histolytica hypothetical protein 0.0661 0.2119 1
Leishmania major DNA polymerase eta, putative 0.0059 0.0127 0.0357
Onchocerca volvulus 0.0049 0.0096 0.0633
Loa Loa (eye worm) hypothetical protein 0.0099 0.026 0.0629
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.0278 0.0753
Brugia malayi CHE-14 protein 0.0044 0.0078 0.0212
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0018 0.0072
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0036 0.0208
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0279
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0094 0.0015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0044 0.0079 0.0214
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0196 0.0924
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0021 0.0094
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.019 0.0562 0.3691
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0275 0.1778
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.049 0.35
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0053 0.0136
Echinococcus multilocularis beta LACTamase domain containing family member 0.0477 0.1509 0.1812
Echinococcus multilocularis importin subunit beta 1 0.0119 0.0326 0.0391
Trichomonas vaginalis hypothetical protein 0.0022 0.0008 0.0043
Schistosoma mansoni hypothetical protein 0.0042 0.0073 0.0135
Schistosoma mansoni thyroid hormone receptor 0.0104 0.0278 0.0513
Schistosoma mansoni pyruvate kinase 0.0034 0.0046 0.0085
Schistosoma mansoni patched 1 0.0044 0.0078 0.0144
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0 0.0001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0074 0.044
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0186 0.1191
Trypanosoma brucei hypothetical protein, conserved 0.0477 0.1509 1
Schistosoma mansoni hypothetical protein 0.0661 0.2119 0.3922
Plasmodium vivax hexose transporter 0.0103 0.0275 0.1778
Loa Loa (eye worm) hypothetical protein 0.0054 0.0111 0.0268
Brugia malayi AMP-binding enzyme family protein 0.1135 0.3685 1
Echinococcus granulosus neuropeptide s receptor 0.0925 0.299 0.5535
Echinococcus granulosus GPCR family 2 0.0193 0.057 0.1055
Onchocerca volvulus 0.0477 0.1509 1
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Onchocerca volvulus 0.0047 0.009 0.0595
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.0096 0.0177
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0042 0.0077
Loa Loa (eye worm) hypothetical protein 0.0088 0.0223 0.0542
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0104 0.0278 0.0753
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0099 0.026 0.0704
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0099 0.026 0.068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0278 0.0513
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0157 0.0452 0.1097
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Echinococcus multilocularis smad 0.0033 0.0042 0.005
Brugia malayi nuclear hormone receptor 0.0049 0.0096 0.026
Echinococcus multilocularis long chain fatty acid transport protein 4 0.105 0.3404 0.4087
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0068 0.0397
Mycobacterium ulcerans lipase LipD 0.0477 0.1509 0.408
Echinococcus multilocularis solute carrier family 5 0.019 0.0562 0.0674
Echinococcus granulosus pyruvate kinase 0.0067 0.0154 0.0284
Brugia malayi kap beta 3 protein 0.0022 0.0008 0.0021
Loa Loa (eye worm) importin-beta domain-containing protein 0.0022 0.0008 0.0018
Loa Loa (eye worm) carboxylesterase 0.0071 0.0167 0.0404
Echinococcus granulosus neutral alpha glucosidase AB 0.0109 0.0295 0.0545
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0471 0.1489 0.2756
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.026 0.0747
Leishmania major importin beta-1 subunit, putative 0.0096 0.0251 0.0728
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.001 0.0011
Echinococcus granulosus FTZ F1 alpha 0.0104 0.0278 0.0513
Plasmodium falciparum glutathione reductase 0.0127 0.0355 0.2517
Plasmodium falciparum protein kinase 7 0.0293 0.0903 0.6491
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0157 0.0452 0.1326
Mycobacterium tuberculosis Conserved hypothetical protein 0.0059 0.0127 0.0048
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.0154 0.043
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.001 0.0017
Loa Loa (eye worm) beta-lactamase 0.0477 0.1509 0.3661
Schistosoma mansoni hypothetical protein 0.0034 0.0047 0.0086
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Trichomonas vaginalis D-aminoacylase, putative 0.0477 0.1509 0.8827
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Schistosoma mansoni loxhd1 0.0042 0.0072 0.0133
Loa Loa (eye worm) hypothetical protein 0.0041 0.0068 0.0164
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0177 0.052 0.0962
Leishmania major glucose transporter, lmgt2 0.0032 0.0039 0.0094
Echinococcus multilocularis RUN 0.0042 0.0072 0.0086
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.001 0.0013
Plasmodium falciparum thioredoxin reductase 0.0127 0.0355 0.2517
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0044 0.0079 0.0478
Brugia malayi nuclear receptor NHR-88 0.0049 0.0096 0.026
Echinococcus granulosus sodium:myo inositol cotransporter 0.019 0.0562 0.104
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0088 0.0162
Trypanosoma cruzi importin beta-1 subunit, putative 0.0096 0.0251 0.0721
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0457
Schistosoma mansoni lamin 0.0028 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0104 0.0278 0.0673
Mycobacterium ulcerans hypothetical protein 0.0159 0.0459 0.1222
Plasmodium falciparum thioredoxin reductase 0.0044 0.0079 0.0521
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0053 0.0136
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0109 0.0295 0.1912
Leishmania major glucose transporter, lmgt3 0.0032 0.0039 0.0094
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0397
Echinococcus granulosus importin 5 0.0022 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Toxoplasma gondii thioredoxin reductase 0.0127 0.0355 0.2312
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0055 0.0115 0.0279
Trypanosoma brucei glycosyl hydrolase-like protein 0.0041 0.0068 0.0402
Trichomonas vaginalis helicase, putative 0.0026 0.002 0.0118
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0127 0.0321
Schistosoma mansoni hypothetical protein 0.0193 0.057 0.1055
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.0154 0.0972
Plasmodium falciparum importin beta, putative 0.0119 0.0326 0.2306
Trichomonas vaginalis D-aminoacylase, putative 0.0477 0.1509 0.8827
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0039 0.0211
Loa Loa (eye worm) acetyltransferase 0.0295 0.0908 0.2202
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0104 0.0278 0.0753
Schistosoma mansoni ap endonuclease 0.0099 0.0259 0.0479
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0094 0.0174
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0157 0.0452 0.296
Schistosoma mansoni thyroid hormone receptor 0.0104 0.0278 0.0513
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0068 0.0184
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.105 0.3404 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0044 0.0079 0.3334
Trypanosoma cruzi hexose transporter 0.0032 0.0039 0.0096
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0044 0.0079 0.0478
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0405 0.1187
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1036 0.3359 1
Schistosoma mansoni cpg binding protein 0.0116 0.0317 0.0587
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0452 0.2644
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0295 0.1723
Brugia malayi MH2 domain containing protein 0.0481 0.1524 0.4135
Echinococcus granulosus importin subunit beta 1 0.0119 0.0326 0.0602
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0508
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0127 0.0048
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0047 0.0056
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0152 0.0411
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.001 0.0009
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.0266 0.0319
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0127 0.0744
Brugia malayi conserved hypotetical protein 0.0049 0.0096 0.026
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1135 0.3685 1
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.0278 0.0753
Schistosoma mansoni inositol transporter 0.019 0.0562 0.104
Brugia malayi CXXC zinc finger family protein 0.0116 0.0317 0.0861
Echinococcus granulosus mitogen activated protein kinase 3 0.0157 0.0452 0.0836
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.022 0.1414
Schistosoma mansoni hypothetical protein 0.0042 0.0073 0.0135
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0477 0.1509 0.2793
Schistosoma mansoni lipoxygenase 0.0042 0.0072 0.0133
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.0096 0.0232
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0094 0.0259
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0068 0.032
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0046 0.0258
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0154 0.1016
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0097
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0086
Trypanosoma brucei glucosidase, putative 0.0109 0.0295 0.1912
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0099 0.026 0.0745
Echinococcus granulosus lamin 0.0028 0.0026 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0182
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.0166
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0055 0.0115 0.0213
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0044 0.0052
Echinococcus granulosus peregrin 0.0066 0.0152 0.0282
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.002 0.0118
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0094 0.0113
Schistosoma mansoni importin-beta 2 0.0022 0.0008 0.0014
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0 0.0001
Loa Loa (eye worm) RNA binding protein 0.0126 0.0349 0.0847
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0042 0.005
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0099 0.026 0.1827
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0044 0.0079 0.0147
Brugia malayi G-protein alpha subunit 0.002 0 0.0001
Trypanosoma brucei unspecified product 0.0059 0.0127 0.0798
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0074 0.0198
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0079 0.0215
Echinococcus granulosus transportin 1 0.0022 0.0008 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0104 0.0278 0.0673
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.0278 0.0753
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0099 0.026 0.0182
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.105 0.3404 1
Trichomonas vaginalis glucosylceramidase, putative 0.0371 0.1162 0.6794
Loa Loa (eye worm) hypothetical protein 0.0102 0.0271 0.0657
Schistosoma mansoni sodium/solute symporter 0.019 0.0562 0.104
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0177 0.052 0.1411
Schistosoma mansoni retinoic acid receptor RXR 0.0104 0.0278 0.0513
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0459 0.0382
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0099 0.026 0.1678
Entamoeba histolytica Ran family GTPase 0.0066 0.0152 0.0714
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0044 0.0079 0.019
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0219 0.1409
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.254 0.8329 1
Brugia malayi isocitrate dehydrogenase 0.0049 0.0094 0.0256
Treponema pallidum exodeoxyribonuclease (exoA) 0.0099 0.0259 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.049 0.3215
Echinococcus granulosus acetylcholinesterase 0.0071 0.0167 0.0308
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0219 0.1409
Entamoeba histolytica deoxycytidyl transferase, putative 0.0059 0.0127 0.06
Entamoeba histolytica hypothetical protein 0.0661 0.2119 1
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.0931 0.2754
Brugia malayi Pre-SET motif family protein 0.021 0.0627 0.17
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0044 0.008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0104 0.0278 0.0333
Echinococcus multilocularis lamin 0.0028 0.0026 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0104 0.0278 0.0673
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.014 0.0884
Trypanosoma brucei glucose transporter, putative 0.0032 0.0039 0.0211
Schistosoma mansoni zinc finger protein 0.0049 0.0096 0.0177
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.001 0.0006
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.019 0.0562 0.0674
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Mycobacterium tuberculosis Conserved protein 0.0477 0.1509 0.1441
Trichomonas vaginalis alpha-glucosidase, putative 0.0109 0.0295 0.1723
Echinococcus multilocularis mitogen activated protein kinase 3 0.0157 0.0452 0.0543
Entamoeba histolytica HEAT repeat domain containing protein 0.0022 0.0008 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0251 0.147
Echinococcus granulosus beta LACTamase domain containing family member 0.0477 0.1509 0.2793
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.002 0.0118
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.026 0.0747
Loa Loa (eye worm) acetylcholinesterase 1 0.0071 0.0167 0.0404
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.0271 0.0501
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0471 0.1489 0.1787
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.0121 0.0223
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0044 0.0261
Brugia malayi AMP-binding enzyme family protein 0.0099 0.026 0.0704
Schistosoma mansoni ran 0.0066 0.0152 0.028
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0068 0.0397
Echinococcus multilocularis peregrin 0.0066 0.0152 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0104 0.0278 0.0753
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0039 0.0228
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0127 0.0356
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0167 0.02
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0127 0.0357
Brugia malayi glutathione reductase 0.0127 0.0355 0.0963
Schistosoma mansoni intermediate filament proteins 0.0028 0.0026 0.0047
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0055 0.0115 0.0213
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0023
Onchocerca volvulus 0.0099 0.026 0.1719
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0099 0.0259 0.0743
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0078 0.0189
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0072 0.0086
Loa Loa (eye worm) hypothetical protein 0.0059 0.0127 0.0309
Echinococcus granulosus sodium:glucose cotransporter 2 0.019 0.0562 0.104
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0056 0.0103
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0099 0.0259 1
Loa Loa (eye worm) TAR-binding protein 0.0126 0.0349 0.0847
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.0266 0.077
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0099 0.026 0.0704
Schistosoma mansoni importin beta-1 0.0119 0.0326 0.0602
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0661 0.2119 0.2544
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.026 0.068
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0039 0.0211
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0193 0.057 0.0685
Schistosoma mansoni steroid hormone receptor ad4bp 0.0104 0.0278 0.0513
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0099 0.026 0.0745
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0193 0.0572 0.0687
Loa Loa (eye worm) follicle stimulating hormone receptor 0.047 0.1488 0.361
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.171 1
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0041 0.0068 0.0449
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0329
Schistosoma mansoni FFA transport protein 0.105 0.3404 0.6301
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0039 0.0228
Echinococcus multilocularis geminin 0.1539 0.5022 0.6029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0046
Brugia malayi Smad1 0.0033 0.0042 0.0113
Echinococcus multilocularis thyroid hormone receptor alpha 0.0104 0.0278 0.0333
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0018 0.0035
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0018 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0088 0.0105
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0128 0.0805
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0177 0.052 0.0962
Schistosoma mansoni hypothetical protein 0.0103 0.0275 0.0508
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0182
Schistosoma mansoni alpha-glucosidase 0.0424 0.1335 0.247
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0068 0.0397
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.026 0.0747
Loa Loa (eye worm) hypothetical protein 0.0126 0.0351 0.0851
Schistosoma mansoni hypothetical protein 0.1654 0.5403 1
Brugia malayi intermediate filament protein 0.0028 0.0026 0.007
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0068 0.0397
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1267 0.4121 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0128 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0266 0.1553
Brugia malayi hypothetical protein 0.0042 0.0072 0.0196
Brugia malayi hypothetical protein 0.0049 0.0096 0.026
Schistosoma mansoni glucose transport protein 0.0103 0.0275 0.0508
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0204 0.0606 0.1122
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0072 0.043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0099 0.0259 0.0628
Schistosoma mansoni hypothetical protein 0.0193 0.057 0.1055
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0099 0.026 0.0182
Brugia malayi hypothetical protein 0.0055 0.0115 0.0313
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0275 0.0508
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0537 0.171 0.4148
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.0154 0.0972
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0039 0.0211
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0193 0.057 0.1055
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0397
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0053 0.03
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.1099 0.6427
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0096 0.0115
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0074 0.0198
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.014 0.0259
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0099 0.026 0.0182
Schistosoma mansoni smad 0.0033 0.0042 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0127 0.0346
Echinococcus granulosus dnaJ subfamily B 0.1654 0.5403 1
Loa Loa (eye worm) hypothetical protein 0.0609 0.1947 0.4723
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.004 0.0216
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0115 0.0213
Echinococcus granulosus thioredoxin glutathione reductase 0.0129 0.0358 0.0663
Onchocerca volvulus 0.0047 0.0088 0.0579
Trypanosoma brucei trypanothione reductase 0.0127 0.0355 0.2312
Schistosoma mansoni survival motor neuron protein 0.0047 0.009 0.0166
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Echinococcus granulosus pyruvate kinase 0.0034 0.0046 0.0085
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0099 0.0259 0.1675
Schistosoma mansoni alpha-glucosidase 0.0424 0.1335 0.247
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0118
Leishmania major DNA polymerase kappa, putative 0.0059 0.0127 0.0357
Brugia malayi Carboxylesterase family protein 0.0071 0.0167 0.0453
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0109 0.0295 0.1723
Plasmodium falciparum pyruvate kinase 0.0067 0.0154 0.1058
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0078 0.0144
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0094 0.0578
Loa Loa (eye worm) hypothetical protein 0.0477 0.1509 0.3661
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0104 0.0278 0.0673
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.026 0.0182
Brugia malayi hypothetical protein 0.0049 0.0097 0.0263
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0251 0.147
Entamoeba histolytica hypothetical protein 0.0026 0.0018 0.0086
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0018 0.0034
Trichomonas vaginalis glutathione reductase, putative 0.0044 0.0079 0.0464
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0099 0.0259 0.0311
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0099 0.026 0.0182
Schistosoma mansoni lamin 0.0028 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0104 0.0278 0.0513
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0044 0.008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0232
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0074 0.0198
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0127 0.0356
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.022 0.0407
Schistosoma mansoni alpha glucosidase 0.0109 0.0295 0.0545
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0186 0.053
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0104 0.0278 0.1838
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0127 0.0321
Entamoeba histolytica acyl-coA synthetase, putative 0.0099 0.026 0.1224
Brugia malayi hypothetical protein 0.0661 0.2119 0.5751
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0104 0.0278 0.0753
Loa Loa (eye worm) hypothetical protein 0.0099 0.026 0.0629
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0104 0.0278 0.0513
Mycobacterium leprae conserved hypothetical protein 0.0477 0.1509 0.4477
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.0278 0.0753
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0044 0.0079 0.0478
Trichomonas vaginalis importin beta-1, putative 0.0096 0.0251 0.147
Echinococcus multilocularis Smad4 0.0033 0.0042 0.005
Schistosoma mansoni RAR-like nuclear receptor 0.0104 0.0278 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0127 0.0798
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0099 0.026 0.068
Loa Loa (eye worm) hypothetical protein 0.0088 0.0223 0.0542
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0096 0.0177
Loa Loa (eye worm) jmjC domain-containing protein 0.0078 0.0191 0.0464
Brugia malayi nuclear receptor RXR 0.0049 0.0096 0.026
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0193 0.057 0.1548
Loa Loa (eye worm) hypothetical protein 0.0119 0.0326 0.079
Trichomonas vaginalis esterase, putative 0.0477 0.1509 0.8827
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0477 0.1509 0.2793
Schistosoma mansoni hypothetical protein 0.0042 0.0072 0.0133

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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