Detailed information for compound 801213

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 495.521 | Formula: C27H29NO8
  • H donors: 1 H acceptors: 4 LogP: 2.31 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCOC(=C1C(=NC2=C(C1c1coc3c(c1=O)cc(cc3)C)C(=O)C(C(C2)C)C(=O)OC)C)O
  • InChi: 1S/C27H29NO8/c1-13-6-7-19-16(10-13)24(29)17(12-36-19)22-21(27(32)35-9-8-33-4)15(3)28-18-11-14(2)20(26(31)34-5)25(30)23(18)22/h6-7,10,12,14,20,22,32H,8-9,11H2,1-5H3
  • InChiKey: AIVBVJIKSVCILY-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0318 0.2703 0.8133
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0415 0.3921
Brugia malayi Serine/threonine-protein kinase Pim-3 0.035 0.3047 0.3303
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0415 0.3921
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0091 0.0302 0.0315
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.0207 0.0029
Entamoeba histolytica protein kinase, putative 0.0072 0.0101 0.0208
Brugia malayi Protein kinase domain containing protein 0.0554 0.5197 0.564
Echinococcus granulosus serine threonine protein kinase nrc 0.0157 0.0998 0.0964
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0415 0.084
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.2027 0.2707
Echinococcus granulosus dual specificity 0.0139 0.0813 0.0778
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0706 0.0755
Onchocerca volvulus 0.0141 0.0836 0.1819
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0101 0.0063
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0881 0.0946
Echinococcus granulosus cyclin dependent kinase 0.0119 0.0602 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.1861 0.2484
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0129 0.0706 0.2004
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0415 0.3921
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.011 0.051 0.0542
Loa Loa (eye worm) hypothetical protein 0.0081 0.0194 0.0198
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0079 0.0179 0.0142
Brugia malayi RhoGAP domain containing protein 0.0098 0.0378 0.0403
Echinococcus granulosus tyrosine protein kinase shark 0.0315 0.2674 0.2646
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0196 0.141 0.1377
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0068 0.0064 0.0057
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0415 0.3921
Echinococcus multilocularis cyclin dependent kinase 5 0.0119 0.0602 0.0695
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0415 0.246
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1791 0.1759
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0248
Schistosoma mansoni tyrosine kinase 0.0145 0.0871 0.1159
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0295 0.0852
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Entamoeba histolytica protein kinase, putative 0.0084 0.0229 0.0598
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0496 0.0565
Echinococcus granulosus serine:threonine protein kinase 0.0115 0.0553 0.0517
Echinococcus granulosus aurora kinase A 0.0146 0.0881 0.0847
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0378 0.0403
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0236 0.0803
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.0967 0.4058
Trichomonas vaginalis AGC family protein kinase 0.0204 0.15 0.5341
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Trypanosoma cruzi casein kinase, putative 0.0109 0.0496 0.1767
Echinococcus multilocularis dual specificity 0.0139 0.0813 0.0952
Giardia lamblia Kinase, CDC7 0.009 0.0299 0.0329
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0154 0.0967 0.3308
Brugia malayi Protein kinase domain containing protein 0.0189 0.1343 0.1452
Entamoeba histolytica protein kinase, putative 0.0146 0.0881 0.2585
Brugia malayi serine/threonine kinase 12 0.0146 0.0881 0.095
Loa Loa (eye worm) thyroid receptor interactor 0.0116 0.0565 0.0602
Trichomonas vaginalis STE family protein kinase 0.0065 0.0033 0.0074
Echinococcus multilocularis insulin receptor 0.0399 0.3558 0.43
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0153 0.0962 0.1033
Loa Loa (eye worm) hypothetical protein 0.0065 0.0035 0.0025
Echinococcus multilocularis aurora kinase A 0.0146 0.0881 0.1035
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0472
Echinococcus multilocularis epidermal growth factor receptor 0.0459 0.4191 0.5072
Echinococcus granulosus serine:threonine protein kinase N2 0.0324 0.2766 0.2738
Brugia malayi serine/threonine-protein kinase 6 0.0146 0.0881 0.095
Entamoeba histolytica hypothetical protein 0.0123 0.0638 0.1844
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Echinococcus granulosus ephrin type A receptor 4 A 0.0111 0.0512 0.0475
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0159 0.1024 0.1101
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0212 0.0219
Echinococcus multilocularis microtubule associated protein 2 0.0769 0.7471 0.9073
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0511 0.1836
Leishmania major protein kinase, putative 0.0154 0.0967 0.3406
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0415 0.0466
Schistosoma mansoni tyrosine kinase 0.0078 0.017 0.022
Trypanosoma cruzi aurora B kinase, putative 0.0146 0.0881 0.3643
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0215 0.1619 0.1587
Trypanosoma brucei Casein kinase II 0.0101 0.0407 0.1262
Echinococcus multilocularis dual specificity 0.0123 0.0638 0.0739
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0123 0.0638 0.1938
Trypanosoma cruzi Protein kinase B 0.0165 0.1091 0.4666
Schistosoma mansoni protein kinase 0.0065 0.0033 0.0036
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0295 0.0313
Echinococcus granulosus protein kinase shaggy 0.0129 0.0706 0.067
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0229 0.2167
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0621
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0245 0.0647
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0085 0.0236 0.0138
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0638 0.2459
Schistosoma mansoni protein kinase 0.0235 0.1831 0.2444
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0768 0.102
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0196 0.141 0.168
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0234 0.1817 0.1786
Echinococcus multilocularis roundabout 2 0.0119 0.0603 0.0696
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.1303 0.1737
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0299 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.1076 0.1433
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2275 0.304
Schistosoma mansoni serine/threonine protein kinase 0.011 0.051 0.0675
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0414 0.3722 0.45
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1817 0.2427
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0145 0.0873 0.0839
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0496 0.0565
Loa Loa (eye worm) hypothetical protein 0.0357 0.3113 0.3372
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0145 0.0871 0.1159
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0098 0.0378 0.0342
Schistosoma mansoni tyrosine kinase 0.0321 0.274 0.3662
Schistosoma mansoni protein kinase 0.0146 0.0881 0.1173
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0185 0.1303 0.1408
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0881 0.3122
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.026 0.0222
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0229 0.0285
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0295 0.0786
Echinococcus multilocularis Immunoglobulin 0.0071 0.0092 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0072 0.0101 0.0083
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.028 0.0243
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1791 0.1759
Brugia malayi Protein kinase domain containing protein 0.0284 0.2349 0.2545
Echinococcus granulosus growth factor receptor bound protein 2 0.0099 0.0392 0.0355
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0295 0.0403
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.0038 0.0029
Entamoeba histolytica protein kinase , putative 0.0146 0.0881 0.2585
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0229 0.0237
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0496 0.0527
Leishmania major protein kinase, putative 0.0085 0.0245 0.0181
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0217 0.1636 0.1766
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0087 0.026 0.0277
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0446 0.4054 0.4905
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0245 0.0647
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0881 0.2585
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0236 0.0803
Onchocerca volvulus 0.0309 0.2607 0.5729
Echinococcus granulosus epidermal growth factor receptor 0.0459 0.4191 0.4169
Loa Loa (eye worm) SRC-1 0.0232 0.1791 0.1934
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0135 0.0768 0.0896
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0146 0.0881 0.1035
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Echinococcus granulosus Vam6:Vps39 protein 0.0111 0.0511 0.0475
Trichomonas vaginalis STE family protein kinase 0.0136 0.0784 0.2771
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0085 0.0236 0.0497
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0191 0.1361 0.162
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.3482 0.4656
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0099 0.0384 0.3634
Echinococcus granulosus neuroglian 0.0089 0.0288 0.0251
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0098 0.0378 0.0499
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0446 0.4054 0.4395
Schistosoma mansoni vav2 0.0107 0.0472 0.0624
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0364 0.3195 0.3169
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0415 0.246
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.028 0.0366
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0071 0.0092 0.0116
Entamoeba histolytica protein kinase, putative 0.0327 0.2797 0.8418
Entamoeba histolytica protein kinase, putative 0.0139 0.0813 0.2377
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0154 0.0967 0.3049
Trypanosoma brucei protein kinase, putative 0.0082 0.0205 0.0522
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0135 0.0768 0.2252
Loa Loa (eye worm) hypothetical protein 0.0113 0.0542 0.0577
Echinococcus multilocularis tyrosine protein kinase HCK 0.0134 0.0762 0.0889
Brugia malayi serine/threonine protein kinase 6 0.0146 0.0881 0.095
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0157 0.0998 0.1177
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0215 0.1619 0.1935
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0706 0.249
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1791 0.2144
Schistosoma mansoni tyrosine kinase 0.0315 0.2674 0.3573
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0511 0.1836
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Echinococcus granulosus insulin receptor 0.0399 0.3558 0.3534
Echinococcus granulosus protein kinase C gamma type 0.0236 0.1838 0.1807
Trypanosoma cruzi casein kinase II, putative 0.0101 0.0407 0.1331
Leishmania major protein kinase A catalytic subunit 0.0113 0.0542 0.1507
Schistosoma mansoni nephrin 0.0105 0.0452 0.0597
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0068 0.0062 0.5
Loa Loa (eye worm) IKK protein kinase 0.0492 0.4542 0.4925
Echinococcus multilocularis rac serine:threonine kinase 0.0165 0.1091 0.1291
Loa Loa (eye worm) hypothetical protein 0.0137 0.0793 0.085
Schistosoma mansoni serine/threonine kinase 0.0196 0.141 0.1881
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.0496 0.0527
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0431 0.3897 0.3874
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0243 0.1915 0.2296
Toxoplasma gondii AGC kinase 0.0318 0.2703 1
Onchocerca volvulus 0.009 0.0299 0.0634
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0299 0.1029
Brugia malayi casein kinase I 0.0109 0.0496 0.0532
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0165 0.1091 0.4666
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0104 0.0441 0.1244
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0602 0.212
Brugia malayi Protein kinase domain containing protein 0.0119 0.0602 0.0647
Schistosoma mansoni microtubule-associated protein tau 0.0769 0.7471 1
Echinococcus granulosus titin 0.0068 0.0064 0.0026
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0277 0.2275 0.2735
Loa Loa (eye worm) protein kinase domain-containing protein 0.0213 0.159 0.1716
Loa Loa (eye worm) hypothetical protein 0.0142 0.0843 0.0904
Schistosoma mansoni tyrosine kinase 0.0459 0.4191 0.5606
Trypanosoma cruzi casein kinase, putative 0.0109 0.0496 0.1767
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1791 0.1759
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0212 0.0718
Brugia malayi SRC-1 0.0232 0.1791 0.1938
Loa Loa (eye worm) TK/ABL protein kinase 0.0309 0.261 0.2825
Entamoeba histolytica casein kinase, putative 0.0101 0.0407 0.114
Trichomonas vaginalis STE family protein kinase 0.0087 0.026 0.0889
Echinococcus granulosus protein tyrosine kinase 0.0548 0.5134 0.5116
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0441 0.4009 0.4346
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0119 0.0602 0.1777
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.02 0.1459 0.1426
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.077 0.1024
Schistosoma mansoni protein kinase 0.0101 0.0407 0.0537
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0176 0.1198 0.129
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Onchocerca volvulus Serine\/threonine kinase homolog 0.0269 0.2186 0.48
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0392 0.0517
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0263 0.2123 0.255
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0122 0.0635 0.06
Schistosoma mansoni cell adhesion molecule 0.0101 0.0408 0.0538
Echinococcus multilocularis dual specificity 0.0139 0.0813 0.0952
Giardia lamblia Kinase, CAMK CAMKL 0.0099 0.0384 0.0732
Brugia malayi Protein kinase domain containing protein 0.0213 0.159 0.172
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Echinococcus multilocularis mitogen activated protein kinase 0.0085 0.0236 0.0248
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0542 0.0577
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0236 0.0803
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0299 0.0312
Schistosoma mansoni serine/threonine-protein kinase 0.0165 0.1091 0.1454
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0706 0.249
Echinococcus granulosus serine/threonine protein kinase 0.0165 0.1091 0.1057
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0111 0.0511 0.0583
Trypanosoma cruzi casein kinase, putative 0.0109 0.0496 0.1767
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0392 0.3482 0.4207
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0136 0.0784 0.2317
Echinococcus granulosus fibroblast growth factor receptor 4 0.0243 0.1915 0.1884
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0101 0.0407 0.3849
Toxoplasma gondii AGC kinase 0.0113 0.0542 0.135
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Loa Loa (eye worm) CAMK/PIM protein kinase 0.035 0.3047 0.33
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0146 0.0881 0.2585
Echinococcus multilocularis casein kinase i 0.0109 0.0496 0.0565
Onchocerca volvulus 0.0104 0.0441 0.0948
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0136 0.0784 0.7411
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0299 0.1029
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.0698 0.0663
Loa Loa (eye worm) TK/ALK protein kinase 0.0281 0.2315 0.2504
Loa Loa (eye worm) hypothetical protein 0.0101 0.0415 0.0438
Echinococcus granulosus tyrosine protein kinase Blk 0.0191 0.1361 0.1328
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.0496 0.1767
Brugia malayi C1-like domain containing protein 0.0217 0.1636 0.177
Loa Loa (eye worm) hypothetical protein 0.0229 0.1767 0.1909
Schistosoma mansoni protein kinase 0.0364 0.3195 0.4272
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0511 0.1641
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0164 0.1073 0.1154
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0232 0.1791 0.1759
Loa Loa (eye worm) hypothetical protein 0.0333 0.2861 0.3098
Schistosoma mansoni rap gtpase-activating protein 0.0111 0.0511 0.0676
Brugia malayi Protein kinase domain containing protein 0.0327 0.2797 0.3031
Loa Loa (eye worm) TK/FAK protein kinase 0.0554 0.5197 0.5638
Schistosoma mansoni growth factor receptor-bound protein 0.0097 0.0371 0.0489
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0123 0.0638 0.0681
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0404 0.3613 0.4368
Leishmania major casein kinase II, putative 0.0101 0.0407 0.0904
Echinococcus multilocularis protein kinase shaggy 0.0129 0.0706 0.0821
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0232 0.1791 0.2144
Echinococcus granulosus rho-associated protein kinase 1 0.0323 0.276 0.2732
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0329 0.2825 0.3059
Brugia malayi SH2 domain containing protein 0.0404 0.3613 0.3919
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.1479 0.1973
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0392 0.3482 0.3457
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.2111 0.2286
Trypanosoma brucei rac serine-threonine kinase, putative 0.0327 0.2797 1
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0638 0.0847
Echinococcus granulosus dual specificity 0.0139 0.0813 0.0778
Loa Loa (eye worm) hypothetical protein 0.0595 0.5634 0.6113
Giardia lamblia Aurora kinase 0.0146 0.0881 0.3078
Brugia malayi Protein kinase domain containing protein 0.0445 0.405 0.4394
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0101 0.0083
Brugia malayi Protein kinase domain containing protein 0.0192 0.1376 0.1488
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0232 0.1791 0.2144
Loa Loa (eye worm) hypothetical protein 0.0086 0.0256 0.0266
Giardia lamblia Kinase, CMGC CK2 0.0101 0.0407 0.0839
Schistosoma mansoni tyrosine kinase 0.0548 0.5134 0.687
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0682 0.2404
Giardia lamblia Kinase, AGC AKT 0.0284 0.2348 1
Entamoeba histolytica hypothetical protein 0.0376 0.3316 1
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0881 0.0946
Echinococcus granulosus twitchin 0.0124 0.0651 0.0615
Entamoeba histolytica protein kinase domain containing protein 0.0101 0.0407 0.114
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0269 0.2186 0.2627
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0295 0.0308
Loa Loa (eye worm) hypothetical protein 0.0088 0.0276 0.0287
Trichomonas vaginalis STE family protein kinase 0.0085 0.0245 0.0838
Plasmodium falciparum glycogen synthase kinase 3 0.0129 0.0706 0.5872
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0602 0.0642
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0595 0.5634 0.6113
Trichomonas vaginalis AGC family protein kinase 0.0216 0.1624 0.5788
Echinococcus granulosus protein kinase 0.0153 0.0962 0.0927
Echinococcus granulosus nervana 2 0.0122 0.0635 0.06
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0602 0.2284
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0295 0.0799
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0392 0.3482 0.3773
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0295 0.1057
Loa Loa (eye worm) AGC/NDR protein kinase 0.0196 0.141 0.1521
Echinococcus multilocularis neuroglian 0.0089 0.0288 0.0311
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0182 0.1261 0.4486
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.2766 0.3697
Brugia malayi Protein kinase domain containing protein 0.0281 0.2316 0.2509
Echinococcus granulosus serine:threonine protein kinase 3 0.0256 0.2046 0.2015
Entamoeba histolytica protein kinase domain containing protein 0.0123 0.0638 0.1844
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0111 0.0511 0.0475
Entamoeba histolytica protein kinase, putative 0.0123 0.0638 0.1844
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0415 0.084
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0542 0.3954
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0072 0.0101 0.0063
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0415 0.246
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0212 0.0218
Brugia malayi map kinase activated protein kinase protein 2 0.0392 0.3482 0.3776
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.2186 0.2921
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0215 0.1619 0.1935
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0506
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0491 0.4529 0.5485
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0638 0.2459
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0221 0.1684 0.2014
Echinococcus multilocularis casein kinase ii subunit alpha 0.0101 0.0407 0.0456
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0229 0.0097
Brugia malayi Egg laying defective protein 4 0.0135 0.0768 0.0826
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0236 0.0497
Onchocerca volvulus 0.0137 0.0793 0.1726
Echinococcus granulosus dual specificity 0.0139 0.0813 0.0778
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0048 0.0044
Onchocerca volvulus 0.0323 0.276 0.6066
Schistosoma mansoni tyrosine kinase 0.0399 0.3558 0.4758
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0602 0.2284
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0164 0.1076 0.1157
Echinococcus multilocularis Immunoglobulin 0.0071 0.0092 0.0072
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1791 0.2144
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0119 0.0602 0.0567
Echinococcus granulosus cyclin dependent kinase 1 0.0119 0.0602 0.0567
Giardia lamblia Kinase, AGC PKA 0.0157 0.0998 0.3628
Loa Loa (eye worm) AGC/AKT protein kinase 0.0327 0.2797 0.3028
Brugia malayi Protein kinase domain containing protein 0.0082 0.0212 0.0223
Toxoplasma gondii casein kinase I 0.0109 0.0496 0.1167
Echinococcus granulosus casein kinase ii subunit alpha 0.0101 0.0407 0.037
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0511 0.0676
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0602 0.0695
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0602 0.2284
Brugia malayi protein unc-22 0.0068 0.0064 0.0062
Brugia malayi Stress-activated protein kinase jnk-1 0.0263 0.2123 0.23
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.035 0.3047 0.302
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0415 0.0378
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.035 0.3047 0.3676
Schistosoma mansoni tyrosine kinase 0.0232 0.1791 0.2391
Echinococcus granulosus tyrosine protein kinase Srms 0.0507 0.4704 0.4684
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0212 0.0276
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0229 0.0465
Loa Loa (eye worm) hypothetical protein 0.0141 0.0836 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Brugia malayi protein kinase C II. 0.0238 0.1861 0.2014
Brugia malayi Tyrosine-protein kinase abl-1 0.0223 0.17 0.184
Schistosoma mansoni tyrosine kinase 0.0274 0.224 0.2993
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0415 0.0547
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0185 0.1303 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.011 0.051 0.0675
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0415 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Entamoeba histolytica protein kinase, putative 0.0072 0.0101 0.0208
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0234 0.1817 0.2177
Schistosoma mansoni protein kinase 0.0431 0.3897 0.5213
Echinococcus multilocularis cyclin dependent kinase 0.0119 0.0602 0.0695
Echinococcus granulosus Immunoglobulin 0.0071 0.0092 0.0055
Brugia malayi Protein kinase domain containing protein 0.0399 0.3558 0.3859
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0542 0.0718
Echinococcus granulosus tyrosine kinase 0.0104 0.0441 0.0405
Echinococcus granulosus titin 0.0068 0.0064 0.0026
Echinococcus granulosus activin receptor type 0.0082 0.0205 0.0168
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0415 0.084
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0196 0.141 0.1377
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0232 0.1791 0.2144
Brugia malayi casein kinase 1, delta 0.0109 0.0496 0.0532
Loa Loa (eye worm) hypothetical protein 0.0071 0.0092 0.0088
Plasmodium vivax tyrosine kinase-like protein, putative 0.0082 0.0207 0.196
Brugia malayi Protein kinase domain containing protein 0.035 0.3047 0.3303
Echinococcus granulosus tyrosine kinase 0.0191 0.1361 0.1328
Echinococcus multilocularis tyrosine protein kinase shark 0.0315 0.2674 0.3221
Brugia malayi cyclin-dependent kinase 7 homolog 0.0119 0.0599 0.0643
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0142 0.0842 0.4149
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0415 0.0378
Echinococcus granulosus tyrosine protein kinase Src64B 0.0232 0.1791 0.1759
Plasmodium falciparum protein serine/threonine kinase-1 0.0154 0.0967 0.8934
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0075 0.0133 0.0132
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.0967 0.4058
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0216 0.1629 0.1758
Loa Loa (eye worm) AGC/PKN protein kinase 0.0324 0.2766 0.2995
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.035 0.3047 0.67
Brugia malayi hypothetical protein 0.0221 0.1684 0.1822
Echinococcus granulosus casein kinase I alpha 0.0109 0.0496 0.046
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0212 0.0718
Echinococcus multilocularis titin 0.0068 0.0064 0.0038
Entamoeba histolytica protein kinase, putative 0.0123 0.0638 0.1844
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0215 0.1619 0.1587
Loa Loa (eye worm) AGC/PKG protein kinase 0.0135 0.0768 0.0822
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0048 0.0039
Onchocerca volvulus 0.0183 0.1273 0.2784
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0243 0.1915 0.1884
Schistosoma mansoni tyrosine kinase 0.008 0.0189 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.4054 0.5422
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0295 0.0852
Entamoeba histolytica cell division protein kinase 2, putative 0.0128 0.0692 0.2007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.0256 0.027
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0243 0.1915 0.2296
Schistosoma mansoni protein kinase 0.0192 0.1376 0.1836
Brugia malayi Protein kinase domain containing protein 0.0123 0.0638 0.0686
Toxoplasma gondii aurora kinase 0.0146 0.0881 0.2708
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1817 0.2427
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Echinococcus granulosus protein kinase c iota type 0.0319 0.2714 0.2687
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0431 0.3897 0.4714
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0364 0.3195 0.3461
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.077 0.1024
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0085 0.0236 0.0497
Loa Loa (eye worm) TK/INSR protein kinase 0.0399 0.3558 0.3856
Echinococcus granulosus casein kinase I delta 0.0109 0.0496 0.046
Loa Loa (eye worm) hypothetical protein 0.0118 0.0586 0.0625
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.0698 0.0811
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0097 0.0371 0.0489
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0205 0.0346
Loa Loa (eye worm) hypothetical protein 0.0086 0.0256 0.0266
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0706 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0064 0.0078
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.1024 0.4338
Schistosoma mansoni protein kinase 0.0082 0.0205 0.0266
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0472
Echinococcus granulosus c-Jun N-terminal kinases 0.0263 0.2123 0.2093
Onchocerca volvulus 0.0075 0.0134 0.027
Echinococcus multilocularis growth factor receptor bound protein 2 0.0097 0.0371 0.0412
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0967 0.3428
Echinococcus granulosus cGMP dependent protein kinase 0.0135 0.0768 0.0732
Echinococcus granulosus serine:threonine protein kinase 0.0115 0.0553 0.0517
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.141 0.1881
Schistosoma mansoni protein kinase 0.0264 0.213 0.2845
Leishmania major protein kinase, putative 0.0146 0.0881 0.3025
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0129 0.0706 0.067
Trypanosoma cruzi polo-like protein kinase, putative 0.0269 0.2186 1
Brugia malayi Kinase associated domain 1 family protein 0.0101 0.0408 0.0435
Echinococcus multilocularis tyrosine protein kinase 0.0284 0.2349 0.2826
Echinococcus granulosus c src tyrosine kinase 0.0145 0.0871 0.0836
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0602 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.141 0.1881
Loa Loa (eye worm) hypothetical protein 0.0137 0.0793 0.085
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Giardia lamblia Kinase, STE STE20 0.0085 0.0245 0.0077
Brugia malayi intracellular kinase 0.0129 0.0706 0.0759
Loa Loa (eye worm) hypothetical protein 0.0097 0.0371 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Brugia malayi hypothetical protein 0.0111 0.0511 0.0547
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0542 0.1755
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0881 0.3122
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0087 0.026 0.0222
Schistosoma mansoni adapter molecule crk 0.0097 0.0371 0.0489
Schistosoma mansoni serine/threonine protein kinase 0.035 0.3047 0.4073
Echinococcus multilocularis serine:threonine protein kinase 0.0115 0.0553 0.0635
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0329 0.2825 0.3062
Loa Loa (eye worm) hypothetical protein 0.0115 0.0553 0.0589
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.026 0.0222
Echinococcus multilocularis calcium activated potassium channel 0.0135 0.077 0.0899
Schistosoma mansoni nck2/grb4 0.0097 0.0371 0.0489
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1941 1
Echinococcus multilocularis casein kinase I delta 0.0109 0.0496 0.0565
Onchocerca volvulus 0.009 0.0299 0.0634
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0232 0.1791 0.2144
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0085 0.0244 0.0207
Entamoeba histolytica PH domain containing protein kinase, putative 0.0165 0.1091 0.3224
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0146 0.0881 0.2585
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0245 0.0671
Loa Loa (eye worm) TK protein kinase 0.0347 0.3015 0.3265
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0602 0.212
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0122 0.0635 0.0735
Schistosoma mansoni tyrosine kinase 0.0399 0.3558 0.4758
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0542 0.0581
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Echinococcus multilocularis expressed protein 0.0084 0.0229 0.0239
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0235 0.1831 0.2193
Echinococcus granulosus cGMP dependent protein kinase 1 0.0135 0.0768 0.0732
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0245 0.0544
Schistosoma mansoni tyrosine kinase 0.0145 0.0871 0.1159
Echinococcus granulosus cGMP dependent protein kinase 1 0.0135 0.0768 0.0732
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0284 0.2348 0.2544
Schistosoma mansoni serine/threonine kinase 0.0225 0.1718 0.2294
Echinococcus multilocularis tyrosine kinase 0.0104 0.0441 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2275 0.304
Mycobacterium ulcerans hypothetical protein 0.0101 0.0405 0.4398
Schistosoma mansoni serine/threonine-protein kinase 0.0165 0.1091 0.1454
Brugia malayi Protein kinase domain containing protein 0.009 0.0299 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0768 0.102
Onchocerca volvulus 0.0104 0.0441 0.0948
Giardia lamblia Kinase, NEK 0.0136 0.0784 0.2617
Giardia lamblia Kinase, CMGC DYRK 0.0139 0.0813 0.2757
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0212 0.0223
Entamoeba histolytica protein kinase domain containing protein 0.0202 0.1479 0.4404
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0235 0.1831 0.18
Schistosoma mansoni protein kinase 0.0153 0.0962 0.128
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0146 0.0881 0.8334
Toxoplasma gondii CMGC kinase, CK2 family 0.0101 0.0407 0.0809
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0706 0.2248
Schistosoma mansoni tyrosine kinase 0.0243 0.1915 0.2558
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0636 0.1836
Brugia malayi Protein kinase domain 0.0087 0.026 0.0274
Echinococcus granulosus tyrosine protein kinase Lyn 0.0266 0.2153 0.2123
Echinococcus granulosus nervana 2 0.0122 0.0635 0.06
Schistosoma mansoni vesicular amine transporter 0.0071 0.0092 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0295 0.0387
Giardia lamblia Kinase, PLK 0.0269 0.2186 0.9235
Loa Loa (eye worm) TK protein kinase 0.0262 0.2111 0.2282
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0164 0.1076 0.1042
Echinococcus granulosus cyclin dependent kinase 5 0.0119 0.0602 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.0496 0.1261
Brugia malayi Protein kinase domain containing protein 0.0364 0.3195 0.3464
Echinococcus granulosus dual specificity protein kinase clk2 0.0154 0.0967 0.0932
Loa Loa (eye worm) hypothetical protein 0.0119 0.0604 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0564 0.198
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.0207 0.001
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0145 0.0875 0.084
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Plasmodium vivax serine/threonine kinase-1, putative 0.0154 0.0967 0.914
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.1024 0.1209
Echinococcus granulosus Protein kinase C brain isozyme 0.0277 0.2275 0.2246
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0881 0.1173
Echinococcus multilocularis nervana 2 0.0122 0.0635 0.0735
Loa Loa (eye worm) hypothetical protein 0.0104 0.0439 0.0465
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0881 0.3122
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0232 0.1791 0.1759
Brugia malayi Protein kinase domain containing protein 0.0164 0.1076 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0473 0.4347 0.5816
Entamoeba histolytica protein kinase domain containing protein 0.0082 0.0205 0.0524
Echinococcus multilocularis N chimaerin 0.0098 0.0378 0.0422
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0157 0.0998 0.421
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0295 0.032
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0621
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0415 0.1289
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0119 0.0602 0.1591
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0299 0.0262
Schistosoma mansoni protein kinase 0.0431 0.3897 0.5213
Echinococcus multilocularis protein kinase c iota type 0.0319 0.2714 0.3271
Brugia malayi Protein kinase domain containing protein 0.0595 0.5634 0.6115
Entamoeba histolytica protein kinase, putative 0.0327 0.2797 0.8418
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0085 0.0236 0.0244
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0139 0.0813 0.0872
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.02 0.1459 0.1574
Onchocerca volvulus 0.0289 0.2397 0.5266
Trichomonas vaginalis AGC family protein kinase 0.0216 0.1624 0.5788
Schistosoma mansoni protein kinase 0.0087 0.026 0.034
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0159 0.1024 0.3662
Echinococcus granulosus hypothetical protein 0.0119 0.0604 0.0568
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0511 0.0676
Echinococcus granulosus NCK adaptor protein 0.0097 0.0371 0.0334
Entamoeba histolytica serine/threonine protein kinase, putative 0.0269 0.2186 0.6558
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0236 0.0803
Entamoeba histolytica protein kinase domain containing protein 0.0139 0.0813 0.2377
Echinococcus granulosus mitogen activated protein kinase 14 0.0159 0.1024 0.099
Entamoeba histolytica protein kinase 2, putative 0.0157 0.0998 0.2939
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0142 0.0842 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0542 0.1989
Echinococcus multilocularis mitogen activated protein kinase 3 0.0085 0.0236 0.0248
Echinococcus multilocularis nervana 2 0.0122 0.0635 0.0735
Brugia malayi hypothetical protein 0.0104 0.0441 0.0472
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0236 0.0497
Schistosoma mansoni hypothetical protein 0.0101 0.0408 0.0538
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0542 0.1507
Echinococcus multilocularis NCK adaptor protein 0.0099 0.0392 0.0438
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0139 0.0813 0.0876
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0445 0.405 0.4391
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0542 0.1903
Loa Loa (eye worm) TK/EPH protein kinase 0.0128 0.0695 0.0743
Loa Loa (eye worm) hypothetical protein 0.0126 0.0671 0.0717
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.1619 0.216
Plasmodium falciparum NIMA related kinase 1 0.0136 0.0784 0.6789
Giardia lamblia Kinase, CMGC CLK 0.0154 0.0967 0.348
Entamoeba histolytica protein kinase, putative 0.0074 0.0126 0.0285
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0145 0.0873 0.1025
Entamoeba histolytica protein kinase, putative 0.0103 0.0428 0.1203
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.0496 0.1588
Schistosoma mansoni tyrosine kinase 0.0232 0.1791 0.2391
Giardia lamblia Kinase, CAMK CAMKL 0.0099 0.0384 0.0732
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0202 0.1479 0.1764
Loa Loa (eye worm) hypothetical protein 0.0179 0.1231 0.1325
Trypanosoma cruzi casein kinase, putative 0.0109 0.0496 0.1767
Schistosoma mansoni ste20-related kinase 0.0205 0.1505 0.2008
Leishmania major protein kinase, putative 0.0101 0.0415 0.0938
Echinococcus multilocularis expressed conserved protein 0.0135 0.0768 0.0896
Echinococcus granulosus casein kinase I gamma 0.0213 0.159 0.1558
Brugia malayi Protein kinase domain containing protein 0.0084 0.0229 0.0241
Loa Loa (eye worm) TK protein kinase 0.0191 0.1361 0.1467
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0881 0.0946
Schistosoma mansoni titin 0.0068 0.0064 0.0078
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0196 0.141 0.168
Loa Loa (eye worm) TK/FER protein kinase 0.0404 0.3613 0.3916
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Echinococcus multilocularis cyclin dependent kinase 7 0.011 0.051 0.0582
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0098 0.0378 0.0499
Plasmodium vivax protein kinase Crk2 0.0119 0.0602 0.5696
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0098 0.0378 0.0422
Entamoeba histolytica protein kinase, putative 0.0082 0.0212 0.0546
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0295 0.0387
Echinococcus granulosus epidermal growth factor receptor 0.0321 0.274 0.2712
Brugia malayi ephrin receptor 1 precursor 0.0077 0.0158 0.0164
Onchocerca volvulus 0.0104 0.0441 0.0948
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.026 0.0277
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.028 0.0301
Loa Loa (eye worm) hypothetical protein 0.0111 0.0511 0.0543
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0157 0.0998 0.93
Trichomonas vaginalis STE family protein kinase 0.0087 0.026 0.0889
Plasmodium falciparum cGMP-dependent protein kinase 0.0135 0.0768 0.6599
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0139 0.0813 0.272
Loa Loa (eye worm) hypothetical protein 0.0101 0.0408 0.043
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0129 0.0706 0.0821
Loa Loa (eye worm) hypothetical protein 0.0183 0.1273 0.1371
Echinococcus multilocularis dual specificity 0.0139 0.0813 0.0952
Plasmodium falciparum protein kinase 5 0.0119 0.0602 0.4662
Echinococcus multilocularis calcium dependent protein kinase 0.0067 0.0052 0.0023
Schistosoma mansoni atypical protein kinase C 0.0325 0.2778 0.3713
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0967 0.1287
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Schistosoma mansoni vam6/vps39 related 0.0111 0.0511 0.0676
Giardia lamblia Kinase, NEK 0.0136 0.0784 0.2617
Echinococcus multilocularis serine:threonine protein kinase 38 0.0196 0.141 0.168
Echinococcus granulosus roundabout 2 0.0119 0.0603 0.0567
Leishmania major protein kinase, putative 0.0154 0.0967 0.3406
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0116 0.0564 0.0647
Trypanosoma brucei aurora B kinase 0.0146 0.0881 0.2996
Echinococcus multilocularis activin receptor type 0.0082 0.0205 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0564 0.198
Schistosoma mansoni hypothetical protein 0.0101 0.0408 0.0538
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.1024 0.1209
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0216 0.1624 0.1753
Echinococcus granulosus tyrosine protein kinase HCK 0.0134 0.0762 0.0727
Entamoeba histolytica protein kinase, putative 0.0129 0.0706 0.2049
Trypanosoma cruzi casein kinase, putative 0.0109 0.0496 0.1767
Schistosoma mansoni protein kinase 0.0087 0.026 0.034
Loa Loa (eye worm) casein kinase 0.0178 0.1227 0.1322
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0542 0.1989
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0116 0.0564 0.0528
Toxoplasma gondii cell-cycle-associated protein kinase, putative 0.0154 0.0968 0.3056
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0299 0.0392
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0602 0.0695
Onchocerca volvulus 0.0104 0.0441 0.0948
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.026 0.0277
Brugia malayi Protein kinase domain containing protein 0.0154 0.0967 0.1043
Entamoeba histolytica casein kinase, putative 0.0109 0.0496 0.1412
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1684 0.2247
Onchocerca volvulus 0.0104 0.0441 0.0948
Echinococcus multilocularis serine:threonine protein kinase 3 0.0256 0.2046 0.2455
Echinococcus multilocularis hypothetical protein 0.0101 0.0408 0.0457
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0472
Echinococcus granulosus calcium activated potassium channel 0.0135 0.077 0.0735
Echinococcus granulosus Glutaredoxin protein 5 0.0122 0.0635 0.06
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0164 0.1076 0.1272
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0415 0.1445
Entamoeba histolytica protein kinase, putative 0.0084 0.0229 0.0598
Brugia malayi Protein kinase c protein 2 0.0116 0.057 0.0612
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0202 0.1479 0.1446
Loa Loa (eye worm) CAMK protein kinase 0.0068 0.0064 0.0057
Echinococcus granulosus N chimaerin 0.0098 0.0378 0.0342
Brugia malayi Protein kinase domain containing protein 0.0115 0.0553 0.0594
Schistosoma mansoni protein kinase 0.0235 0.1831 0.2444
Onchocerca volvulus 0.0111 0.0511 0.1102
Loa Loa (eye worm) hypothetical protein 0.0237 0.1849 0.1998
Trypanosoma brucei cdc2-related kinase 1 0.0119 0.0602 0.1976
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0542 0.0718
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0205 0.0346
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0269 0.2186 0.2156
Entamoeba histolytica PH domain containing protein kinase, putative 0.0165 0.1091 0.3224
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0602 0.1762
Onchocerca volvulus 0.0492 0.4542 1
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0496 0.0565
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0542 0.135
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.276 0.3689
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0146 0.0882 0.1036
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0496 0.0657
Entamoeba histolytica protein kinase, putative 0.0091 0.0304 0.0825
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0066 0.0038 0.0006
Trypanosoma brucei protein kinase, putative 0.0093 0.0325 0.0962
Loa Loa (eye worm) hypothetical protein 0.0071 0.0092 0.0088
Brugia malayi Furin-like cysteine rich region family protein 0.0459 0.4191 0.4547
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0408 0.366 0.3636
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0602 0.2284
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0185 0.1303 0.127
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0415 0.246
Loa Loa (eye worm) hypothetical protein 0.0141 0.0836 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0097 0.0371 0.0391
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0295 0.0258
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Echinococcus multilocularis death associated protein kinase 1 0.0841 0.8231 1
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0602 0.1762
Giardia lamblia Kinase, AGC PKA 0.0113 0.0542 0.1476
Echinococcus multilocularis tyrosine protein kinase Abl 0.0223 0.17 0.2034
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0542 0.1989
Brugia malayi Protein kinase domain containing protein 0.0196 0.141 0.1525
Schistosoma mansoni tyrosine kinase 0.0274 0.224 0.2993
Echinococcus multilocularis serine threonine protein kinase 0.0236 0.1838 0.2202
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0101 0.0407 0.043
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0813 0.1082
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0154 0.0967 0.3308
Brugia malayi Temporarily assigned gene name protein 59 0.0111 0.0511 0.0547
Schistosoma mansoni protein kinase 0.0109 0.0496 0.0657
Entamoeba histolytica p21-activated kinase 0.0096 0.0353 0.0975
Trichomonas vaginalis STE family protein kinase 0.0087 0.026 0.0889
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.0967 0.4058
Brugia malayi Casein kinase II, alpha chain 0.0101 0.0407 0.0435
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0071 0.0092 0.0116
Brugia malayi probable protein kinase 0.0264 0.213 0.2307
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0621
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Echinococcus multilocularis serine:threonine protein kinase 0.0115 0.0553 0.0635
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0191 0.1361 0.1328
Onchocerca volvulus 0.0129 0.0706 0.1532
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0245 0.0544
Loa Loa (eye worm) hypothetical protein 0.0137 0.0793 0.085
Loa Loa (eye worm) hypothetical protein 0.0104 0.0441 0.0467
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0129 0.0706 0.0937
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0496 0.1739
Echinococcus multilocularis epidermal growth factor receptor 0.0321 0.274 0.3302
Echinococcus granulosus tyrosine protein kinase ABL1 0.0309 0.261 0.2582
Plasmodium falciparum casein kinase 1 0.0109 0.0496 0.3419
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0415 0.0378
Echinococcus multilocularis protein kinase c epsilon type 0.0238 0.1861 0.223
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0407 0.1418
Loa Loa (eye worm) TK protein kinase 0.0134 0.0762 0.0816
Plasmodium falciparum MO15-related protein kinase 0.0162 0.1058 1
Entamoeba histolytica protein kinase, putative 0.0196 0.141 0.4195
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0706 0.2248
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0408 0.366 0.4425
Plasmodium vivax glycogen synthase kinase 3, putative 0.0129 0.0706 0.6672
Echinococcus multilocularis Glutaredoxin protein 5 0.0122 0.0635 0.0735
Echinococcus multilocularis 0.0153 0.0962 0.1133
Echinococcus granulosus dual specificity 0.0123 0.0638 0.0603
Onchocerca volvulus 0.0191 0.1367 0.2991
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0813 0.3311
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0232 0.1791 0.2144
Schistosoma mansoni tyrosine kinase 0.0321 0.274 0.3662
Onchocerca volvulus 0.0077 0.0156 0.0318
Echinococcus multilocularis serine:threonine protein kinase N2 0.0196 0.141 0.168
Loa Loa (eye worm) hypothetical protein 0.0086 0.0256 0.0266
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0295 0.0361
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0083 0.0216 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0295 0.0387
Echinococcus granulosus calcium dependent protein kinase 0.0067 0.0052 0.0014
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0221 0.1684 0.1818
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0321 0.274 0.2712
Brugia malayi Doublecortin family protein 0.0151 0.0937 0.1011
Brugia malayi STE20-like kinase MST 0.0256 0.2046 0.2215
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0236 0.0308
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0119 0.0602 0.0642
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0491 0.4529 0.4509
Brugia malayi Protein kinase domain containing protein 0.0193 0.1386 0.1498
Echinococcus multilocularis myosin iiia 0.0085 0.0245 0.0259
Giardia lamblia Kinase, NEK 0.0136 0.0784 0.2617
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0295 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.2123 0.2836
Loa Loa (eye worm) hypothetical protein 0.0085 0.0244 0.0252
Plasmodium vivax unspecified product 0.0101 0.0407 0.3849
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0256 0.2046 0.2211
Echinococcus multilocularis casein kinase I gamma 0.0213 0.159 0.1899
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0135 0.0768 0.0896
Brugia malayi Fibronectin type III domain containing protein 0.0086 0.0256 0.027
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0415 0.0438
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0119 0.0602 0.1777
Echinococcus granulosus expressed protein 0.0084 0.0229 0.0192
Brugia malayi Serine/threonine-protein kinase SULU 0.0221 0.1684 0.1822
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0157 0.0998 0.9436
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0123 0.0638 0.2108
Schistosoma mansoni serine/threonine protein kinase 0.02 0.1459 0.1947
Brugia malayi Immunoglobulin I-set domain containing protein 0.0441 0.4009 0.4349
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0415 0.0443
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0129 0.0706 0.2239
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0269 0.2186 0.2364
Echinococcus multilocularis 0.0119 0.0604 0.0697
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0192 0.1376 0.1484
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.1619 0.216
Echinococcus granulosus casein kinase I delta 0.0109 0.0496 0.046
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0706 0.2049
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0212 0.0175
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0318 0.2703 0.2926
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0472
Trichomonas vaginalis AGC family protein kinase 0.0225 0.1717 0.6124
Schistosoma mansoni tyrosine kinase 0.0252 0.2011 0.2686
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0238 0.1861 0.201
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0263 0.2123 0.2296
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0159 0.1024 0.3518
Brugia malayi protein kinase C3,putative 0.0158 0.1009 0.1089
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0542 0.1755
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0217 0.1636 0.177
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0085 0.0236 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.2186 0.7808
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0542 0.0718
Onchocerca volvulus 0.0079 0.0177 0.0364
Echinococcus granulosus mitogen activated protein kinase 11 0.0159 0.1024 0.099
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0185 0.1303 0.1404
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0115 0.0553 0.0589
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0415 0.0466
Echinococcus granulosus mitogen activated protein kinase 3 0.0085 0.0236 0.0199
Loa Loa (eye worm) hypothetical protein 0.0111 0.0511 0.0543
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0636 0.1836
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0146 0.0881 0.2585
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0415 0.0438
Brugia malayi Protein kinase domain containing protein 0.0595 0.5634 0.6115
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0595 0.5634 0.6113
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0221 0.1684 0.1652
Echinococcus granulosus tyrosine protein kinase 0.0284 0.2349 0.232
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0371 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0881 0.3122
Onchocerca volvulus Tyrosine kinase homolog 0.0375 0.3303 0.7265
Schistosoma mansoni tyrosine kinase 0.0274 0.224 0.2993
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0091 0.0304 0.0825
Plasmodium vivax casein kinase 1, putative 0.0109 0.0496 0.4694
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0542 0.1755
Giardia lamblia Kinase, STE STE20 0.0087 0.026 0.0144
Brugia malayi P38 map kinase family protein 2 0.0159 0.1024 0.1105
Schistosoma mansoni ephrin receptor 0.0111 0.0512 0.0677
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0295 0.0786
Brugia malayi p70 ribosomal S6 kinase beta 0.0318 0.2703 0.293
Echinococcus multilocularis tyrosine protein kinase Srms 0.0191 0.1361 0.162
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.0967 0.4058
Echinococcus granulosus microtubule associated protein 2 0.0769 0.7471 0.7461
Brugia malayi protein-tyrosine kinase 0.0191 0.1361 0.1471
Loa Loa (eye worm) hypothetical protein 0.0111 0.0511 0.0543
Onchocerca volvulus Serine\/threonine kinase homolog 0.0164 0.1076 0.2349
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0542 0.1507
Loa Loa (eye worm) CAMK/PIM protein kinase 0.035 0.3047 0.33
Echinococcus granulosus tyrosine protein kinase Src42A 0.0146 0.0882 0.0847
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0506
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0813 0.2877
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0162 0.1058 1
Brugia malayi cell division control protein 2 homolog 0.0119 0.0602 0.0647
Loa Loa (eye worm) hypothetical protein 0.0456 0.4167 0.4518
Trypanosoma brucei polo-like protein kinase 0.0269 0.2186 0.7768
Echinococcus multilocularis ephrin type A receptor 4 A 0.0111 0.0512 0.0584
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0145 0.0875 0.1027
Trypanosoma brucei cdc2-related kinase 3 0.0119 0.0602 0.1976
Brugia malayi Cam kinase protein 1 0.0101 0.0415 0.0443
Echinococcus granulosus casein kinase i 0.0109 0.0496 0.046
Entamoeba histolytica protein kinase, putative 0.0087 0.026 0.0691
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0205 0.0522
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0404 0.3613 0.3589
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0784 0.2771
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0151 0.0937 0.1006
Plasmodium falciparum serine/threonine protein kinase, putative 0.0146 0.0881 0.7934
Brugia malayi SH2 domain containing protein 0.0104 0.0441 0.0472
Brugia malayi Protein kinase domain containing protein 0.0216 0.1624 0.1757
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0371 0.0395
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0542 0.0621
Onchocerca volvulus 0.0068 0.0064 0.0116
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0706 0.2049
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0154 0.0967 0.1038
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.159 0.2122
Schistosoma mansoni protein kinase C mu 0.0217 0.1636 0.2183
Schistosoma mansoni tyrosine kinase 0.037 0.3251 0.4347
Brugia malayi Sex muscle abnormal protein 5 0.0097 0.0371 0.0395
Loa Loa (eye worm) hypothetical protein 0.0104 0.0439 0.0465
Loa Loa (eye worm) hypothetical protein 0.009 0.0295 0.0308
Echinococcus granulosus protein kinase c epsilon type 0.0238 0.1861 0.183
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0202 0.1479 0.1595
Schistosoma mansoni protein kinase 0.0431 0.3897 0.5213
Plasmodium falciparum casein kinase 2, alpha subunit 0.0101 0.0407 0.2371
Echinococcus granulosus casein kinase I alpha 0.0109 0.0496 0.046
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0542 0.5125
Echinococcus multilocularis serine:threonine protein kinase N2 0.0324 0.2766 0.3334
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0414 0.3722 0.3698
Loa Loa (eye worm) hypothetical protein 0.0357 0.3113 0.3372
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0371 0.3266 0.3538
Brugia malayi Hr1 repeat family protein 0.0324 0.2766 0.2998
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0302 0.1039
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0146 0.0881 0.0847
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0309 0.261 0.3143
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0098 0.0378 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0602 0.0799
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0085 0.0236 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.077 0.1024
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0157 0.0998 0.0964
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0682 0.2404
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0364 0.3195 0.3857
Echinococcus multilocularis tyrosine protein kinase Blk 0.0191 0.1361 0.162
Echinococcus multilocularis dual specificity protein kinase clk2 0.0154 0.0967 0.1139
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0232 0.1791 0.2144
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0602 0.212
Brugia malayi Protein kinase domain containing protein 0.02 0.1459 0.1578
Entamoeba histolytica protein kinase, putative 0.0101 0.0415 0.1163
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0602 0.0642
Echinococcus granulosus NDR protein kinase 0.0196 0.141 0.1377
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0079 0.0177 0.0179
Entamoeba histolytica protein kinase, putative 0.0074 0.0126 0.0285
Echinococcus multilocularis c src tyrosine kinase 0.0145 0.0871 0.1022
Leishmania major casein kinase, putative 0.0109 0.0496 0.1303
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1791 0.2144
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0071 0.0095 0.0091
Onchocerca volvulus 0.0104 0.0441 0.0948
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0293 0.2442 1
Loa Loa (eye worm) TK protein kinase 0.0284 0.2349 0.2542
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0202 0.1479 0.1599
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0101 0.0127
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0967 0.1287
Echinococcus multilocularis 0.0126 0.0673 0.0781
Echinococcus multilocularis rho associated protein kinase 0.0323 0.276 0.3326
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0139 0.0813 0.2436
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0542 0.1989
Echinococcus granulosus mitogen activated protein kinase 0.0085 0.0236 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0071 0.0092 0.0072
Entamoeba histolytica protein kinase, putative 0.0134 0.0762 0.2221
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0446 0.4054 0.4031
Echinococcus multilocularis protein tyrosine kinase 0.0548 0.5134 0.6223
Trichomonas vaginalis AGC family protein kinase 0.0327 0.2797 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0269 0.2186 0.2368
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0085 0.0236 0.0635
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0602 0.1735
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.02 0.1459 0.174
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0079 0.0179 0.0179
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0229 0.1767 0.1736
Brugia malayi serine/threonine-protein kinase PAK 7 0.0231 0.1787 0.1934
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0496 0.1739
Trichomonas vaginalis STE family protein kinase 0.0087 0.026 0.0889
Brugia malayi Protein kinase domain containing protein 0.0216 0.1629 0.1762
Trypanosoma cruzi polo-like protein kinase, putative 0.0269 0.2186 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0496 0.0527
Trypanosoma brucei protein kinase, putative 0.0129 0.0706 0.2353
Entamoeba histolytica protein kinase, putative 0.0146 0.0881 0.2585
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2276 0.8128
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0415 0.246
Loa Loa (eye worm) hypothetical protein 0.0206 0.1519 0.1639
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.1024 0.1209
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0295 0.0403
Brugia malayi Tyrosine-protein kinase abl-1 0.0127 0.0682 0.0733
Loa Loa (eye worm) hypothetical protein 0.0191 0.1367 0.1473
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0553 0.1944
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0933 0.9209 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.1024 0.1209
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0542 0.0577
Echinococcus granulosus tyrosine protein kinase Src42A 0.0232 0.1791 0.1759
Giardia lamblia Kinase, CMGC MAPK 0.0085 0.0236 0.0031
Brugia malayi MAP kinase sur-1 0.0085 0.0236 0.0248
Brugia malayi Protein kinase domain containing protein 0.0933 0.9209 1
Echinococcus multilocularis casein kinase I delta 0.0109 0.0496 0.0565
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0813 0.2747
Brugia malayi hypothetical protein 0.0086 0.0256 0.027
Schistosoma mansoni tyrosine kinase 0.0258 0.2075 0.2771
Loa Loa (eye worm) hypothetical protein 0.0088 0.0276 0.0287
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0496 0.1739
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.06 0.0796
Trichomonas vaginalis CAMK family protein kinase 0.0216 0.1629 0.5806
Schistosoma mansoni hypothetical protein 0.0111 0.0511 0.0676
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0129 0.0706 0.2786
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.1024 0.4338
Loa Loa (eye worm) TK/EGFR protein kinase 0.0459 0.4191 0.4544
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0299 0.1029
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0229 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0229 0.0299
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0231 0.1787 0.193
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0229 0.0611
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0097 0.0371 0.0391
Brugia malayi Protein kinase domain containing protein 0.0492 0.4542 0.4928
Entamoeba histolytica casein kinase 1, putative 0.0109 0.0496 0.1412
Echinococcus granulosus cyclin dependent kinase 7 0.011 0.051 0.0474
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0269 0.2186 0.8858
Brugia malayi Fes/CIP4 homology domain containing protein 0.0116 0.0565 0.0607
Echinococcus granulosus casein kinase I alpha 0.0109 0.0496 0.046
Brugia malayi Temporarily assigned gene name protein 59 0.0128 0.0691 0.0743
Schistosoma mansoni kinase 0.0287 0.2379 0.3179
Toxoplasma gondii AGC kinase 0.0113 0.0542 0.135
Echinococcus granulosus defective proboscis extension response 0.0071 0.0092 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0295 0.1016
Onchocerca volvulus 0.0109 0.0496 0.107

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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