Detailed information for compound 86601

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 416.938 | Formula: C24H29ClO4
  • H donors: 0 H acceptors: 3 LogP: 3.64 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@@]1(CCC2C1(C)CCC1C2C=C(C2=CC(=O)[C@H]3[C@@H](C12C)C3)Cl)C(=O)C
  • InChi: 1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14?,15-,16?,17?,18+,22?,23?,24+/m1/s1
  • InChiKey: UWFYSQMTEOIJJG-RLTCCVSUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Chromobox protein 3 0.0022 0.0000000022589 0.0000000022589
Mycobacterium tuberculosis Probable esterase LipL 0.0156 0.0136 0.0345
Leishmania major calcium-translocating P-type ATPase 0.0157 0.0137 0.2657
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0002 0.0003
Echinococcus granulosus chromobox protein 1 0.0137 0.0116 0.0116
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni kinase 0.0218 0.0199 0.0511
Loa Loa (eye worm) nuclear receptor nhr-7B 0.006 0.0038 0.0057
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0014 0.0352
Onchocerca volvulus Matrilysin homolog 0.602 0.6091 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0037 0.0056
Echinococcus granulosus flap endonuclease 1 0.0028 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0063 0.1212
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0045 0.0045
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.006 0.0038 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0133 0.0112 0.2161
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0055 0.1377
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0036 0.0014 0.0351
Schistosoma mansoni survival motor neuron protein 0.0097 0.0075 0.0194
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0352 0.0335 0.8361
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0126 0.0106 0.0159
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0124 0.0315
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0002 0.0002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0019 0.0364
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0019 0.0348
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0042 0.002 0.0044
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.033 0.0312 0.0312
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Brugia malayi acetyltransferase, GNAT family protein 0.0313 0.0295 0.0445
Loa Loa (eye worm) RNA binding protein 0.0133 0.0113 0.017
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0103 0.0082 0.1587
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0162 0.0142 0.3535
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0589 0.0576 0.1718
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0075 0.0054 0.1035
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0162 0.0142 0.2752
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0166 0.0146 0.0428
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.0191 0.3714
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.2714 0.2734 0.7035
Brugia malayi nuclear hormone receptor family member odr-7 0.006 0.0038 0.0057
Plasmodium vivax copper-transporting ATPase, putative 0.0031 0.0009 0.034
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0038 0.0038
Onchocerca volvulus 0.0619 0.0606 0.0995
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Echinococcus multilocularis calcium transporting atpase 0.0162 0.0142 0.0142
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0013 0.0026
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Schistosoma mansoni ap endonuclease 0.0041 0.0019 0.0049
Trypanosoma cruzi P-type H+-ATPase, putative 0.008 0.0059 0.1135
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.002
Brugia malayi Protein kinase domain containing protein 0.0031 0.0009 0.0014
Mycobacterium ulcerans hypothetical protein 0.0156 0.0136 0.0398
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.008 0.008
Giardia lamblia DINP protein human, muc B family 0.0189 0.0169 0.4057
Giardia lamblia Kinase, PLK 0.0417 0.0401 0.9775
Leishmania major DNA polymerase kappa, putative 0.0057 0.0035 0.0668
Loa Loa (eye worm) hypothetical protein 0.0228 0.0209 0.0315
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0025 0.0633
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0061 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Toxoplasma gondii GAF domain-containing protein 0.0042 0.002 0.0881
Loa Loa (eye worm) hypothetical protein 0.024 0.0221 0.0332
Treponema pallidum cation-transporting ATPase, P-type 0.0031 0.0009 0.0225
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0025 0.0067
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0048 0.0026 0.0656
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0417 0.0401 0.0401
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0179 0.0159 0.0405
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0121 0.01 0.4365
Loa Loa (eye worm) hypothetical protein 0.0047 0.0025 0.0038
Schistosoma mansoni transient receptor potential channel 4 0.0095 0.0074 0.0191
Loa Loa (eye worm) hypothetical protein 0.0132 0.0112 0.0168
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0019 0.0832
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0426 0.041 0.1054
Trypanosoma brucei DNA polymerase IV, putative 0.021 0.0191 0.3703
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0121 0.01 0.1928
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.009 0.0069 0.1725
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0019 0.037
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0548 0.0533 0.138
Schistosoma mansoni smad 0.0025 0.0002 0.0006
Loa Loa (eye worm) acetyltransferase 0.0313 0.0295 0.0445
Schistosoma mansoni hypothetical protein 0.0034 0.0012 0.003
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0068 0.0068
Brugia malayi hypothetical protein 0.0074 0.0052 0.0079
Loa Loa (eye worm) carboxylesterase 0.0132 0.0112 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0112 0.2798
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Onchocerca volvulus 0.0097 0.0075 0.0124
Trypanosoma brucei trypanothione reductase 0.0057 0.0035 0.0664
Echinococcus granulosus cation transporting ATPase 13A3 0.0031 0.0009 0.0009
Brugia malayi Pre-SET motif family protein 0.0205 0.0186 0.0279
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0121 0.01 0.1942
Trypanosoma brucei unspecified product 0.0203 0.0184 0.3564
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Echinococcus multilocularis FTZ F1 alpha 0.0126 0.0106 0.0106
Schistosoma mansoni cpg binding protein 0.0121 0.01 0.0257
Brugia malayi hypothetical protein 0.033 0.0312 0.047
Echinococcus multilocularis tar DNA binding protein 0.0133 0.0113 0.0113
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.2224 0.2236 0.5753
Trichomonas vaginalis CAMK family protein kinase 0.0213 0.0193 0.4827
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0019 0.037
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0157 0.0137 0.2644
Brugia malayi RNA, U transporter 1 0.008 0.0058 0.0088
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0075 0.0054 0.102
Leishmania major hypothetical protein, conserved 0.0076 0.0054 0.1049
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0031 0.0009 0.0018
Mycobacterium ulcerans dehydrogenase 0.0041 0.0019 0.0049
Mycobacterium ulcerans beta-lactamase 0.0156 0.0136 0.0398
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.0071 0.3091
Echinococcus granulosus phospholipid transporting ATPase IA 0.0036 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0113 0.029
Plasmodium vivax calcium-transporting ATPase, putative 0.0172 0.0152 0.5623
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0005 0.0198
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0067 0.0045 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0009 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0243 0.0224 0.0577
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Brugia malayi ecdysone receptor 0.006 0.0038 0.0057
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0012 0.0012
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0138 0.0118 0.0177
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0031 0.0009 0.0009
Brugia malayi MH1 domain containing protein 0.0025 0.0002 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Entamoeba histolytica hypothetical protein 0.0022 0.0000000000020276 0.000000000050622
Schistosoma mansoni carbonic anhydrase-related 0.0248 0.0229 0.059
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0157 0.0137 0.2657
Entamoeba histolytica hypothetical protein 0.033 0.0312 0.78
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0011 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0025 0.0038
Loa Loa (eye worm) intermediate filament protein 0.0033 0.001 0.0016
Brugia malayi intermediate filament protein 0.0033 0.001 0.0016
Onchocerca volvulus Serine\/threonine kinase homolog 0.0417 0.0401 0.0658
Echinococcus multilocularis protein dispatched 1 0.0048 0.0026 0.0026
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.0112 0.2176
Schistosoma mansoni retinoic acid receptor RXR 0.0246 0.0227 0.0583
Schistosoma mansoni jumonji domain containing protein 0.006 0.0038 0.0098
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0036 0.0014 0.0021
Plasmodium falciparum GAF domain-related protein, putative 0.0042 0.002 0.0881
Onchocerca volvulus 0.0114 0.0093 0.0153
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0156 0.0136 0.0398
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0038 0.0062
Toxoplasma gondii P-type ATPase4, putative 0.0172 0.0152 0.6629
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0054 0.1049
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0126 0.0106 0.0159
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0162 0.0142 0.0364
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0157 0.0137 0.0137
Schistosoma mansoni amine oxidase 0.0041 0.0019 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Onchocerca volvulus 0.0421 0.0405 0.0664
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.012 0.0304
Schistosoma mansoni hypothetical protein 0.03 0.0282 0.0725
Loa Loa (eye worm) hypothetical protein 0.2714 0.2734 0.4116
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Brugia malayi amine oxidase, flavin-containing family protein 0.0041 0.0019 0.0029
Trypanosoma brucei DNA damage repair protein, putative 0.0057 0.0035 0.0653
Brugia malayi MH2 domain containing protein 0.0025 0.0002 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0182 0.0162 0.0244
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0019 0.0019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.001 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0009 0.0024
Echinococcus granulosus mitogen activated protein kinase 0.0075 0.0054 0.0054
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0126 0.0106 0.0272
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0106 0.0159
Loa Loa (eye worm) hypothetical protein 0.0106 0.0085 0.0128
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0068
Echinococcus multilocularis carbonic anhydrase 0.0248 0.0229 0.0229
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0248 0.0229 0.0345
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0126 0.0106 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0054 0.0032 0.0082
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0067 0.0045 0.0045
Onchocerca volvulus 0.006 0.0038 0.0063
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0106 0.0272
Schistosoma mansoni ATPase 0.0157 0.0137 0.0352
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0002 0.0002
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0059 0.0037 0.0055
Trypanosoma cruzi P-type H+-ATPase, putative 0.009 0.0069 0.1336
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0014 0.0021
Echinococcus multilocularis dna polymerase kappa 0.021 0.0191 0.0191
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0172 0.0152 0.0152
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0162 0.0142 0.0364
Leishmania major UDP-galactopyranose mutase 0.0041 0.0019 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Trypanosoma brucei polo-like protein kinase 0.0417 0.0401 0.7794
Trichomonas vaginalis CMGC family protein kinase 0.0075 0.0054 0.1336
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0153 0.2965
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Echinococcus granulosus microtubule associated protein 2 0.2094 0.2104 0.2104
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0113 0.029
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0248 0.0229 0.0345
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0113 0.029
Echinococcus granulosus transient receptor potential gamma protein 0.0095 0.0074 0.0074
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0157 0.0137 0.2657
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0011 0.0021
Trichomonas vaginalis cation-transporting ATPase, putative 0.0157 0.0137 0.3413
Schistosoma mansoni tsg101-related 0.005 0.0028 0.0073
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0068
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Trypanosoma brucei DNA damage repair protein, putative 0.0057 0.0035 0.0653
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0067 0.0046 0.011
Plasmodium vivax cation transporting ATPase, putative 0.0031 0.0009 0.034
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0031 0.0009 0.0018
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.021 0.0191 0.4767
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0031 0.0009 0.0014
Echinococcus granulosus nervana 2 0.0828 0.0819 0.0819
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0162 0.0142 0.0142
Trichomonas vaginalis esterase, putative 0.0156 0.0136 0.3388
Echinococcus granulosus smad 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0619 0.0606 0.0912
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.0093 0.014
Brugia malayi hypothetical protein 0.0106 0.0085 0.0128
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0000000000020276 0.0000000000030524
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0068
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0000000000020276 0.0000000000020276
Echinococcus multilocularis carbonic anhydrase 0.0248 0.0229 0.0229
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0162 0.0142 0.6178
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Echinococcus granulosus jun protein 0.0101 0.008 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0136 0.3388
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0421 0.0405 0.1205
Mycobacterium ulcerans hydrolase 0.3306 0.3335 1
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0036 0.0014 0.0351
Echinococcus granulosus nervana 2 0.0828 0.0819 0.0819
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.009 0.0069 0.1725
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.3306 0.3335 0.502
Schistosoma mansoni ferritin 0.0026 0.0003 0.0008
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0436 0.042 0.0632
Leishmania major aminophospholipid translocase, putative 0.0036 0.0014 0.0267
Brugia malayi nuclear hormone receptor 0.0126 0.0106 0.0159
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0162 0.0142 0.0142
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0166 0.0146 0.0371
Onchocerca volvulus 0.0041 0.0019 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.0313 0.0313
Echinococcus multilocularis mitogen activated protein kinase 14 0.0138 0.0118 0.0118
Loa Loa (eye worm) TAR-binding protein 0.0133 0.0113 0.017
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0289 0.0271 0.0408
Trypanosoma cruzi cation-transporting ATPase, putative 0.0031 0.0009 0.0172
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0036 0.0014 0.0351
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0031 0.0009 0.0229
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0000000000020276 0.0000000000052178
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0006 0.0006
Schistosoma mansoni copper ABC transporter ATPase 0.0031 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0045 0.0068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0182 0.0162 0.0162
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0313 0.0805
Onchocerca volvulus 0.0022 0.0000000022589 0.0000000037084
Loa Loa (eye worm) hypothetical protein 0.0097 0.0076 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0019 0.0476
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0038 0.0038
Toxoplasma gondii exonuclease III APE 0.0041 0.0019 0.0832
Brugia malayi Hemopexin family protein 0.3849 0.3886 0.585
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0528 0.0514 0.0773
Echinococcus multilocularis carbonic anhydrase II 0.0528 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0106 0.0272
Brugia malayi Nuclear hormone receptor-like 1 0.0126 0.0106 0.0159
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0076 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.0172 0.044
Echinococcus multilocularis mitogen activated protein kinase 0.0075 0.0054 0.0054
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0019 0.0597
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Onchocerca volvulus 0.0233 0.0214 0.0352
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0031 0.0009 0.0016
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0426 0.041 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0997 0.0989 0.2566
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0126 0.0106 0.0159
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0025 0.0067
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0289 0.0271 0.0408
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0031 0.0009 0.0018
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0589 0.0576 0.1718
Schistosoma mansoni nuclear receptor 0.006 0.0038 0.0097
Echinococcus granulosus nervana 2 0.0828 0.0819 0.0819
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0035 0.0083
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0106 0.0159
Echinococcus multilocularis copper transporting ATPase 1 0.0031 0.0009 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.021 0.0191 0.0564
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0028 0.0028
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0036 0.0014 0.0014
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0067 0.0045 0.087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0038 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0228 0.0209 0.0315
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0031 0.0009 0.0229
Loa Loa (eye worm) hypothetical protein 0.2714 0.2734 0.4116
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0157 0.0137 0.5965
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Trichomonas vaginalis chromobox protein, putative 0.0083 0.0061 0.1525
Schistosoma mansoni ATPase 0.0157 0.0137 0.0352
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0341 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0047 0.0025 0.0038
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0000000000020276 0.0000000000030524
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0071 0.005 0.0944
Loa Loa (eye worm) nuclear hormone receptor 0.006 0.0038 0.0057
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0042 0.0042
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0248 0.0229 0.0345
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0035 0.0035
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0031 0.0009 0.0095
Echinococcus granulosus Chromo domain 0.0022 0.0000000000020276 0.0000000000020276
Mycobacterium tuberculosis Possible oxidoreductase 0.0041 0.0019 0.0042
Brugia malayi polk-prov protein 0.0085 0.0063 0.0095
Plasmodium vivax DNA repair protein REV1, putative 0.0057 0.0035 0.1284
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0248 0.0229 0.0345
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0045 0.0116
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.4061 0.4101 1
Toxoplasma gondii P-type ATPase PMA1 0.009 0.0069 0.3008
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0159 0.0409
Loa Loa (eye worm) inositol-1 0.0121 0.01 0.0151
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0005 0.0097
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0059 0.0037 0.0037
Schistosoma mansoni microtubule-associated protein tau 0.2094 0.2104 0.5414
Entamoeba histolytica hypothetical protein 0.033 0.0312 0.78
Trichomonas vaginalis cation-transporting ATPase, putative 0.009 0.0069 0.1721
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.008 0.0059 0.2558
Entamoeba histolytica hypothetical protein 0.033 0.0312 0.78
Trichomonas vaginalis chromobox protein, putative 0.0137 0.0116 0.2902
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0007 0.0007
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0012 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0019 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0136 0.2637
Entamoeba histolytica serine/threonine protein kinase, putative 0.0417 0.0401 1
Schistosoma mansoni coup transcription factor 0.0126 0.0106 0.0272
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0172 0.0152 0.6629
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0126 0.0106 0.0272
Schistosoma mansoni hypothetical protein 0.0248 0.0229 0.059
Mycobacterium ulcerans hypothetical protein 0.0057 0.0035 0.0095
Echinococcus multilocularis Chromo domain 0.0022 0.0000000000020276 0.0000000000020276
Loa Loa (eye worm) glutathione reductase 0.0057 0.0035 0.0053
Mycobacterium ulcerans recombinase A 0.0231 0.0212 0.0628
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Mycobacterium ulcerans hypothetical protein 0.0057 0.0035 0.0097
Schistosoma mansoni inositol monophosphatase 0.0121 0.01 0.0257
Trichomonas vaginalis cation-transporting ATPase, putative 0.0157 0.0137 0.3413
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0162 0.0142 0.0364
Echinococcus multilocularis lamin dm0 0.0033 0.001 0.001
Trichomonas vaginalis cation-transporting ATPase, putative 0.0157 0.0137 0.3413
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0037 0.0918
Trypanosoma brucei P-type H+-ATPase, putative 0.009 0.0069 0.1321
Loa Loa (eye worm) hypothetical protein 0.0474 0.0458 0.069
Echinococcus multilocularis protoporphyrinogen oxidase 0.0041 0.0019 0.0019
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0019 0.0019
Schistosoma mansoni nuclear hormone receptor 0.006 0.0038 0.0097
Onchocerca volvulus 0.006 0.0038 0.0062
Schistosoma mansoni jun-related protein 0.0082 0.0061 0.0157
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0172 0.0152 0.3793
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Onchocerca volvulus 0.0156 0.0136 0.0223
Schistosoma mansoni transcription factor LCR-F1 0.033 0.0312 0.0804
Echinococcus granulosus intermediate filament protein 0.0033 0.001 0.001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0126 0.0106 0.0106
Schistosoma mansoni transient receptor potential channel 0.0095 0.0074 0.0191
Brugia malayi Thioredoxin reductase 0.0057 0.0035 0.0053
Brugia malayi hypothetical protein 0.0067 0.0045 0.0068
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0076 0.1896
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0005 0.008
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0351
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0103 0.0082 0.0123
Loa Loa (eye worm) hypothetical protein 0.0828 0.0819 0.1232
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0156 0.0136 0.0345
Echinococcus multilocularis inositol monophosphatase 1 0.0121 0.01 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.0191 0.3714
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0417 0.0401 0.0603
Mycobacterium leprae Conserved hypothetical protein 0.1358 0.1356 0.4061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0000000000020276 0.000000000088471
Trypanosoma brucei hypothetical protein, conserved 0.0156 0.0136 0.2624
Echinococcus granulosus expressed conserved protein 0.0091 0.007 0.007
Brugia malayi Nuclear hormone receptor E75 0.006 0.0038 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0233 0.0214 0.0633
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.0112 0.2176
Leishmania major DNA polymerase kappa, putative 0.0189 0.0169 0.3293
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0006 0.0252
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0106 0.0159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0019 0.0364
Giardia lamblia Copper-transporting P-type ATPase 0.0031 0.0009 0.0095
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Trichomonas vaginalis ferritin, putative 0.0026 0.0003 0.0079
Loa Loa (eye worm) hypothetical protein 0.0828 0.0819 0.1232
Schistosoma mansoni lamin 0.0033 0.001 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0019 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0055 0.1377
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni Smad4 0.0025 0.0002 0.0006
Schistosoma mansoni RAR-like nuclear receptor 0.0126 0.0106 0.0272
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0025 0.0003 0.0122
Toxoplasma gondii histone lysine-specific demethylase 0.0041 0.0019 0.0846
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.017 0.0279
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0047
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0028 0.0065
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0136 0.3388
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Brugia malayi glutathione reductase 0.0057 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0009
Echinococcus granulosus mitogen activated protein kinase 14 0.0138 0.0118 0.0118
Entamoeba histolytica hypothetical protein 0.033 0.0312 0.78
Mycobacterium tuberculosis Conserved protein 0.0156 0.0136 0.0345
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0162 0.0142 0.2739
Onchocerca volvulus 0.0156 0.0136 0.0223
Schistosoma mansoni hypothetical protein 0.0228 0.0209 0.0538
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0121 0.01 0.2497
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0002 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.0573 0.0559 0.0559
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.006 0.0038 0.0097
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.002 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.0191 0.3714
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0077 0.0055 0.0091
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0028 0.1039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0038 0.0038
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0042 0.002 0.0044
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0036 0.0014 0.0216
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0138 0.0118 0.2272
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0002 0.0002
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0028 0.0524
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.033 0.0313 0.0471
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0029 0.0564
Echinococcus granulosus phospholipid transporting ATPase VA 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Brugia malayi Flap endonuclease-1 0.0028 0.0005 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Echinococcus granulosus carbonic anhydrase 0.0248 0.0229 0.0229
Leishmania major DNA polymerase eta, putative 0.0114 0.0093 0.181
Loa Loa (eye worm) calcium ATPase 0.0092 0.0071 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0032 0.0809
Trypanosoma brucei DNA polymerase IV, putative 0.021 0.0191 0.3703
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0351
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0068
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Brugia malayi beta-lactamase 0.0156 0.0136 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.002 0.0489
Leishmania major P-type H -ATPase, putative 0.009 0.0069 0.1336
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0348 0.6767
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0172 0.0152 0.3793
Mycobacterium tuberculosis Conserved protein 0.0156 0.0136 0.0345
Echinococcus multilocularis transient receptor potential gamma protein 0.0095 0.0074 0.0074
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0189 0.0169 0.3293
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0019 0.0718
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0075 0.0054 0.0081
Mycobacterium ulcerans esterase/lipase LipP 0.0156 0.0136 0.0398
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0011 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0014
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.012 0.035
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0063 0.1212
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0074 0.0052 0.0052
Toxoplasma gondii thioredoxin reductase 0.0057 0.0035 0.1538
Plasmodium vivax hypothetical protein, conserved 0.0042 0.002 0.0748
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0036 0.0014 0.0351
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0037 0.0918
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0228 0.0209 0.0209
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0036 0.0014 0.0351
Trypanosoma brucei unspecified product 0.0126 0.0105 0.2022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0028 0.0028
Brugia malayi Matrixin family protein 0.2714 0.2734 0.4116
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0426 0.041 0.041
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0028 0.1225
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0248 0.0229 0.0345
Echinococcus multilocularis ecdysone induced protein 78C 0.0126 0.0106 0.0106
Schistosoma mansoni nuclear receptor 0.006 0.0038 0.0097
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0000000022589 0.0000000022589
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0013 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0126 0.0106 0.0159
Brugia malayi tailless protein 0.006 0.0038 0.0057
Brugia malayi CHD4 protein 0.0029 0.0007 0.001
Toxoplasma gondii hypothetical protein 0.0248 0.0229 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.0206 0.898
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0166 0.0146 0.0428
Mycobacterium tuberculosis Conserved hypothetical protein 0.0182 0.0162 0.0414
Schistosoma mansoni amine oxidase 0.0041 0.0019 0.005
Brugia malayi nuclear receptor RXR 0.0067 0.0045 0.0068
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0025 0.0067
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0828 0.0819 0.2106
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0045 0.0068
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.011 0.0277
Entamoeba histolytica deoxycytidyl transferase, putative 0.0182 0.0162 0.4051
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0025 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0126 0.0106 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0126 0.0106 0.0159
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0133 0.0112 0.2163
Schistosoma mansoni hypothetical protein 0.0493 0.0478 0.1231
Echinococcus granulosus carbonic anhydrase II 0.0528 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Echinococcus granulosus cation transporting atpase worm 0.0031 0.0009 0.0009
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0028 0.0524
Echinococcus multilocularis dnaJ subfamily B 0.1626 0.1629 0.1629
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Brugia malayi hypothetical protein 0.008 0.0058 0.0088
Trichomonas vaginalis DNA polymerase eta, putative 0.021 0.0191 0.4767
Onchocerca volvulus 0.0126 0.0106 0.0173
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0019 0.0476
Onchocerca volvulus 0.008 0.0058 0.0095
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0007 0.0007
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Loa Loa (eye worm) hypothetical protein 0.0331 0.0313 0.0471
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0172 0.0152 0.6629
Brugia malayi jmjC domain containing protein 0.0067 0.0045 0.0067
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0013 0.0575
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0092 0.0071 0.0106
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0248 0.0229 0.0345
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0036 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0493 0.0478 0.072
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0038 0.0038
Trypanosoma brucei cation-transporting ATPase, putative 0.0031 0.0009 0.0155
Plasmodium vivax P-type ATPase4, putative 0.0172 0.0152 0.5623
Brugia malayi P38 map kinase family protein 2 0.0138 0.0118 0.0177
Echinococcus multilocularis cation transporting ATPase 13A3 0.0031 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.002
Echinococcus granulosus geminin 0.0717 0.0705 0.0705
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0041 0.0019 0.0846
Schistosoma mansoni hypothetical protein 0.0097 0.0075 0.0194
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Echinococcus multilocularis jun protein 0.0101 0.008 0.008
Schistosoma mansoni patched 1 0.0042 0.002 0.005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0126 0.0106 0.0106
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0031 0.0009 0.0155
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0031 0.0009 0.0014
Plasmodium falciparum carbonic anhydrase 0.0248 0.0229 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0156 0.0136 0.0349
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0528 0.0514 0.0773
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.005 0.0028 0.0706
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0103 0.0082 0.0123
Leishmania major P-type ATPase, putative 0.0162 0.0142 0.2752
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0106 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.018 0.4498
Echinococcus granulosus histone acetyltransferase KAT2B 0.0305 0.0287 0.0287
Echinococcus granulosus carboxylesterase 5A 0.0132 0.0112 0.0112
Echinococcus multilocularis nervana 2 0.0828 0.0819 0.0819
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0098 0.0077 0.0221
Chlamydia trachomatis protoporphyrinogen oxidase 0.0041 0.0019 0.0502
Brugia malayi serine/threonine-protein kinase plk-2 0.0417 0.0401 0.0603
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0031 0.0009 0.0009
Trypanosoma cruzi P-type H+-ATPase, putative 0.009 0.0069 0.1336
Toxoplasma gondii hypothetical protein 0.0042 0.002 0.0881
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0006 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0361 0.0344 0.0517
Onchocerca volvulus Protein ultraspiracle homolog 0.0126 0.0106 0.0173
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Brugia malayi E1-E2 ATPase family protein 0.0031 0.0009 0.0014
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.0113 0.017
Mycobacterium ulcerans lipase LipD 0.0156 0.0136 0.0398
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0031 0.0009 0.0229
Loa Loa (eye worm) hypothetical protein 0.0095 0.0074 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0025 0.0058
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.0348 0.6767
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0098 0.0077 0.0192
Loa Loa (eye worm) hypothetical protein 0.0099 0.0077 0.0117
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0025 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.011 0.0277
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0067 0.0045 0.0068
Loa Loa (eye worm) hypothetical protein 0.0085 0.0063 0.0095
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0041 0.0019 0.0049
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0035 0.0035
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0133 0.0112 0.0288
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0133 0.0112 0.2163
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0041 0.0019 0.0718
Plasmodium falciparum DNA repair protein REV1, putative 0.0057 0.0035 0.1513
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0054 0.1049
Brugia malayi beta-lactamase family protein 0.0156 0.0136 0.0204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0228 0.0209 0.0315
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0036 0.0014 0.0267
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0036 0.0014 0.025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Mycobacterium tuberculosis Probable hydrolase 0.0156 0.0136 0.0345
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0269 1
Brugia malayi Matrixin family protein 0.2714 0.2734 0.4116
Brugia malayi hypothetical protein 0.0041 0.0019 0.0029
Brugia malayi CXXC zinc finger family protein 0.0114 0.0093 0.014
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0075 0.0054 0.1035
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0076 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0095 0.2384
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0024 0.0001 0.0017
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0288 0.027 1
Plasmodium falciparum copper-transporting ATPase 0.0031 0.0009 0.0401
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Brugia malayi SET domain containing protein 0.0026 0.0004 0.0005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0038 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0028 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0106 0.0106
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0157 0.0137 0.2657
Brugia malayi Matrixin family protein 0.2714 0.2734 0.4116
Plasmodium vivax hypothetical protein, conserved 0.0156 0.0136 0.5023
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0031 0.0009 0.0229
Schistosoma mansoni type V p-type atpase isoform 0.0036 0.0014 0.0036
Leishmania major trypanothione reductase 0.0057 0.0035 0.0679
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0156 0.0136 0.0345
Loa Loa (eye worm) acetylcholinesterase 1 0.0132 0.0112 0.0168
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0377 0.036 0.0542
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0057 0.0035 0.1513
Loa Loa (eye worm) DR-78 0.006 0.0038 0.0057
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0121 0.01 0.1942
Brugia malayi nuclear receptor NHR-88 0.0126 0.0106 0.0159
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0126 0.0106 0.0159
Echinococcus granulosus carbonic anhydrase 0.0248 0.0229 0.0229
Mycobacterium ulcerans putative regulatory protein 0.0042 0.002 0.0051
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Loa Loa (eye worm) hypothetical protein 0.0436 0.042 0.0632
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.009 0.0069 0.1339
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0095 0.2384
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0248 0.0229 0.0345
Loa Loa (eye worm) steroid hormone receptor 0.0126 0.0106 0.0159
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.0112 0.2798
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0126 0.0106 0.0159
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.001 0.0016
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.002 0.002
Leishmania major calcium-transporting ATPase, putative 0.0162 0.0142 0.2752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0121 0.01 0.2497
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0203 0.0184 0.3564
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Schistosoma mansoni ap endonuclease 0.0041 0.0019 0.0049
Brugia malayi Nuclear hormone receptor E75 0.006 0.0038 0.0057
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0074 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0095 0.2384
Echinococcus multilocularis carboxylesterase 5A 0.0132 0.0112 0.0112
Schistosoma mansoni transient receptor potential channel 0.0063 0.0041 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Echinococcus multilocularis 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0189 0.0169 0.0432
Toxoplasma gondii hypothetical protein 0.0042 0.002 0.0881
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0029 0.0548
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0126 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.006 0.0038 0.0057
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0156 0.0136 0.0345
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.008 0.0059 0.1135
Trypanosoma cruzi DNA polymerase eta, putative 0.0114 0.0093 0.181
Echinococcus granulosus dna polymerase eta 0.024 0.0221 0.0221
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0005 0.0008
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0048 0.0026 0.1154
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0095 0.0074 0.1843
Echinococcus multilocularis neuropeptide receptor A26 0.0573 0.0559 0.0559
Echinococcus multilocularis beta LACTamase domain containing family member 0.0156 0.0136 0.0136
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.011 0.0277
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0036 0.0014 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0025 0.0633
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0031 0.0009 0.0024
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3578 0.3611 0.9388
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0019 0.0019
Onchocerca volvulus 0.006 0.0038 0.0062
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0119 0.0098 0.0247
Brugia malayi hypothetical protein 0.0067 0.0045 0.0068
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0025 0.0067
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0007 0.0007
Schistosoma mansoni importin beta-1 0.0028 0.0006 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.0313 0.0313
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0132 0.0112 0.0287
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0031 0.0009 0.0401
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0059 0.0037 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0019 0.0364
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0341 0.0324 0.0487
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Mycobacterium ulcerans oxidoreductase 0.0041 0.0019 0.0049
Brugia malayi hypothetical protein 0.006 0.0038 0.0057
Onchocerca volvulus 0.0828 0.0819 0.1344
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0159 0.0409
Brugia malayi nuclear receptor RXR 0.006 0.0038 0.0057
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0035 0.0668
Mycobacterium leprae conserved hypothetical protein 0.0156 0.0136 0.0398
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0041 0.0041
Brugia malayi hypothetical protein 0.006 0.0038 0.0057
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3809 0.3846 1
Trypanosoma brucei carbonic anhydrase-like protein 0.0528 0.0514 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0014 0.0014
Onchocerca volvulus 0.0033 0.001 0.0017
Brugia malayi ImpB/MucB/SamB family protein 0.0182 0.0162 0.0244
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0179 0.0159 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0000000000020276 0.000000000075057
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0047
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.008 0.0059 0.1135
Leishmania major carbonic anhydrase-like protein 0.0528 0.0514 1
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0828 0.0819 0.2106
Echinococcus granulosus snurportin 1 0.03 0.0282 0.0282
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0528 0.0514 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0341 0.0324 0.0324
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0031 0.0009 0.0018
Echinococcus multilocularis lamin 0.0033 0.001 0.001
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0075 0.0054 0.2334
Schistosoma mansoni intermediate filament proteins 0.0033 0.001 0.0027
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0007 0.0007
Trypanosoma cruzi DNA damage repair protein, putative 0.0057 0.0035 0.0668
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0019 0.0846
Trypanosoma brucei DNA polymerase kappa, putative 0.0189 0.0169 0.3282
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0126 0.0106 0.0159
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.0313 0.0313
Plasmodium vivax glutathione reductase, putative 0.0057 0.0035 0.1305
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0031 0.0009 0.0016
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0041 0.0019 0.005
Echinococcus multilocularis dna polymerase eta 0.024 0.0221 0.0221
Echinococcus multilocularis cpg binding protein 0.0121 0.01 0.01
Treponema pallidum hypothetical protein 0.0047 0.0025 0.0825
Trypanosoma cruzi DNA repair protein, putative 0.0071 0.005 0.096
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0092 0.0071 0.1761
Loa Loa (eye worm) hypothetical protein 0.0077 0.0055 0.0083
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0159 0.0467
Trypanosoma cruzi polo-like protein kinase, putative 0.0417 0.0401 0.7798
Schistosoma mansoni apoferritin-2 0.0026 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.002
Echinococcus multilocularis Smad4 0.0025 0.0002 0.0002
Echinococcus granulosus importin subunit beta 1 0.0028 0.0006 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0126 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.008 0.0059 0.0088
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0000000000020276 0.0000000000020276
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0114 0.0093 0.407
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0059 0.0037 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0054 0.2366
Schistosoma mansoni carbonic anhydrase-related 0.0248 0.0229 0.059
Mycobacterium leprae PROBABLE HYDROLASE 0.3306 0.3335 1
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0031 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.2714 0.2734 0.4116
Echinococcus multilocularis geminin 0.0717 0.0705 0.0705
Brugia malayi nuclear receptor NHR-67 0.006 0.0038 0.0057
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0521
Trypanosoma brucei P-type H+-ATPase, putative 0.009 0.0069 0.1321
Schistosoma mansoni phospholipid-transporting atpase 0.0036 0.0014 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0014
Echinococcus granulosus nuclear receptor nhr 48 0.006 0.0038 0.0038
Schistosoma mansoni nuclear receptor nhr-48 0.006 0.0038 0.0097
Leishmania major hypothetical protein, conserved 0.0156 0.0136 0.2637
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0035 0.0053
Schistosoma mansoni steroid hormone receptor ad4bp 0.0126 0.0106 0.0272
Echinococcus granulosus expressed protein 0.0026 0.0003 0.0003
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Trypanosoma brucei protein kinase, putative 0.0075 0.0054 0.102
Schistosoma mansoni cpg binding protein 0.0121 0.01 0.0257
Loa Loa (eye worm) Smad1 0.0025 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0126 0.0106 0.0159
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0031 0.0009 0.0229
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.002
Trichomonas vaginalis chromobox protein, putative 0.0137 0.0116 0.2902
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0036 0.0014 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0005 0.0097
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0341 0.0324 0.0833
Leishmania major P-type H -ATPase, putative 0.009 0.0069 0.1336
Leishmania major proton motive ATPase, putative 0.0031 0.0009 0.0172
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0006 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0528 0.0514 0.1322
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0047
Echinococcus granulosus beta LACTamase domain containing family member 0.0156 0.0136 0.0136
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0028 0.0028
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.002 0.002
Echinococcus multilocularis expressed conserved protein 0.0091 0.007 0.007
Brugia malayi Steroid receptor seven-up type 2 0.0126 0.0106 0.0159
Onchocerca volvulus Matrix metalloproteinase homolog 0.602 0.6091 1
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0036 0.0014 0.0351
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0041 0.0041
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0019 0.0039
Loa Loa (eye worm) matrixin family protein 0.602 0.6091 0.917
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0124 0.0315
Loa Loa (eye worm) E1-E2 ATPase 0.009 0.0069 0.0104
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni hypothetical protein 0.1626 0.1629 0.4191
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0104 0.0083 0.024
Trichomonas vaginalis penicillin-binding protein, putative 0.0156 0.0136 0.3388
Schistosoma mansoni nuclear hormone receptor 0.006 0.0038 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0417 0.0401 0.1031
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0162 0.0142 0.0364
Echinococcus multilocularis nervana 2 0.0828 0.0819 0.0819
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0121 0.01 0.1942
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0036 0.0014 0.0021
Echinococcus multilocularis nervana 2 0.0828 0.0819 0.0819
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.0458 0.0458
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0186 0.0279
Brugia malayi Matrixin family protein 0.2714 0.2734 0.4116
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0029 0.0564
Loa Loa (eye worm) hypothetical protein 0.0722 0.071 0.1069
Brugia malayi bZIP transcription factor family protein 0.0101 0.008 0.0121
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0005 0.0233
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0126 0.0106 0.0272
Echinococcus granulosus Smad4 0.0025 0.0002 0.0002
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0162 0.0142 0.0364
Trypanosoma brucei calcium-translocating P-type ATPase 0.0162 0.0142 0.2739
Schistosoma mansoni ferritin light chain 0.0026 0.0003 0.0008
Echinococcus multilocularis cation transporting atpase worm 0.0031 0.0009 0.0009
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0005 0.0133
Schistosoma mansoni smad1 5 8 and 0.0025 0.0002 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0133 0.0112 0.2161
Mycobacterium tuberculosis Probable lipase LipD 0.0156 0.0136 0.0345
Trypanosoma brucei chrX additional, unordered contigs 0.0057 0.0035 0.0653
Mycobacterium tuberculosis Probable reductase 0.013 0.011 0.0277
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0031 0.0009 0.0018
Brugia malayi Carboxylesterase family protein 0.0132 0.0112 0.0168
Brugia malayi MH2 domain containing protein 0.0025 0.0002 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0035 0.0679
Brugia malayi photoreceptor-specific nuclear receptor 0.0126 0.0106 0.0159
Echinococcus granulosus Protein patched homolog 1 0.0042 0.002 0.002
Entamoeba histolytica acetyltransferase, GNAT family 0.0084 0.0063 0.1574
Giardia lamblia Histone acetyltransferase GCN5 0.0084 0.0063 0.1427
Echinococcus multilocularis cation transporting ATPase 13A1 0.0031 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.018 0.4498
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0025 0.0038
Schistosoma mansoni zinc finger protein 0.006 0.0038 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0133 0.0112 0.2161
Brugia malayi Carboxylesterase family protein 0.0132 0.0112 0.0168
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0038 0.0038
Onchocerca volvulus 0.0033 0.001 0.0017
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Echinococcus granulosus dna polymerase kappa 0.021 0.0191 0.0191
Brugia malayi hypothetical protein 0.0076 0.0054 0.0082
Schistosoma mansoni eyes absent homolog 0.0106 0.0085 0.0219
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0038 0.0062
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0036 0.0014 0.0014
Echinococcus multilocularis smad 0.0025 0.0002 0.0002
Loa Loa (eye worm) carbonic anhydrase 3 0.0528 0.0514 0.0773
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0528 0.0514 0.1322
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0106 0.0159
Loa Loa (eye worm) hypothetical protein 0.0059 0.0037 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0156 0.0136 0.3388
Onchocerca volvulus Bile acid receptor homolog 0.0126 0.0106 0.0173
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0016
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0121 0.01 0.0236
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0036 0.0014 0.025
Loa Loa (eye worm) hypothetical protein 0.0157 0.0137 0.0206
Trichomonas vaginalis hypothetical protein 0.0036 0.0014 0.0344
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0722 0.071 0.1069
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0035 0.0668
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0035 0.0653
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0036 0.0014 0.0267
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0228 0.0209 0.0209
Brugia malayi Matrixin family protein 0.6563 0.6643 1
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0119 0.0098 0.0285
Schistosoma mansoni cation-transporting atpase worm 0.0031 0.0009 0.0024
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.0113 0.017
Schistosoma mansoni ferritin 0.0026 0.0003 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0126 0.0106 0.0173
Plasmodium vivax importin-beta 2, putative 0.0028 0.0006 0.0214
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0156 0.0136 0.0349
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0024 0.0001 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Onchocerca volvulus 0.0047 0.0025 0.0042
Brugia malayi MAP kinase sur-1 0.0075 0.0054 0.0081
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0019 0.0029
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.3306 0.3335 0.8669
Schistosoma mansoni DNA polymerase eta 0.024 0.0221 0.0568
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0133 0.0112 0.0112
Brugia malayi RNA binding protein 0.0133 0.0113 0.017
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0035 0.1305
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0045 0.0115
Schistosoma mansoni smad1 5 8 and 0.0025 0.0002 0.0006
Brugia malayi hypothetical protein 0.0025 0.0003 0.0004
Echinococcus multilocularis GPCR, family 2 0.0228 0.0209 0.0209
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.0112 0.2798
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0118 0.0118
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0077 0.0055 0.1382
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0005 0.0133
Brugia malayi nuclear hormone receptor family member nhr-6 0.006 0.0038 0.0057
Trichomonas vaginalis cation-transporting ATPase, putative 0.0036 0.0014 0.0351
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0028 0.054
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0041 0.0019 0.0049
Toxoplasma gondii hypothetical protein 0.0059 0.0037 0.1614
Brugia malayi Isocitrate dehydrogenase 0.005 0.0028 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0048 0.0026 0.0656
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0068 0.0068
Brugia malayi N-terminal motif family protein 0.0178 0.0158 0.0237
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0126 0.0106 0.0106
Chlamydia trachomatis recombinase RecA 0.0231 0.0212 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0037 0.0918
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0162 0.0142 0.0142
Leishmania major DNA damage repair protein, putative 0.0057 0.0035 0.0668
Trypanosoma cruzi polo-like protein kinase, putative 0.0417 0.0401 0.7798
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0005 0.0005
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0828 0.0819 0.2106
Brugia malayi hypothetical protein 0.0619 0.0606 0.0912
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0036 0.0014 0.0351
Giardia lamblia Kinase, CMGC MAPK 0.0075 0.0054 0.1191
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0228 0.0209 0.0209
Schistosoma mansoni carbonic anhydrase-related 0.0248 0.0229 0.059
Onchocerca volvulus 0.0828 0.0819 0.1344
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0075 0.0054 0.1035
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.3306 0.3335 0.502
Toxoplasma gondii hypothetical protein 0.0116 0.0095 0.4166
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0028 0.0028
Echinococcus granulosus neuropeptide receptor A26 0.0573 0.0559 0.0559
Schistosoma mansoni ferritin light chain 0.0026 0.0003 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0313 0.0295 0.076
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0025 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Schistosoma mansoni type V p-type atpase isoform 0.0031 0.0009 0.0024
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0828 0.0819 0.2106
Echinococcus granulosus carbonic anhydrase 0.0248 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0348 0.6767
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0172 0.0152 0.0152
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0025 0.0067
Mycobacterium ulcerans putative regulatory protein 0.0042 0.002 0.0051
Echinococcus multilocularis ferritin 0.0026 0.0003 0.0003
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.9869 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0014
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.008 0.0059 0.0088
Mycobacterium tuberculosis Probable lipase LipE 0.0156 0.0136 0.0345
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0108 0.0087 0.0219
Mycobacterium leprae Probable lipase LipE 0.0156 0.0136 0.0398
Echinococcus granulosus mitogen activated protein kinase 3 0.0075 0.0054 0.0054
Trichomonas vaginalis cation-transporting ATPase, putative 0.0036 0.0014 0.0351
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.0112 0.2176
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0162 0.0142 0.0142
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0126 0.0106 0.0106
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0417 0.0401 0.7798
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0113 0.029
Echinococcus multilocularis protein patched 0.0042 0.002 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0106 0.0106
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0013 0.0488
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0019 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0025 0.0038
Trypanosoma cruzi DNA polymerase eta, putative 0.024 0.0221 0.4297
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0179 0.0159 0.3088
Schistosoma mansoni DNA polymerase IV / kappa 0.0057 0.0035 0.0089
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0077 0.0199
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0377 0.036 0.0542
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0138 0.0118 0.2285
Mycobacterium ulcerans hypothetical protein 0.0047 0.0025 0.0067
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0014 0.0014
Brugia malayi steroid hormone receptor 0.0126 0.0106 0.0159
Treponema pallidum recombinase A 0.0231 0.0212 0.7861
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.0191 0.3714
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0036 0.0014 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0014 0.0352
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0075 0.0054 0.1035
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0009 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.011 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0031 0.0009 0.0172
Trypanosoma cruzi DNA repair protein, putative 0.0071 0.005 0.096
Onchocerca volvulus 0.2714 0.2734 0.4488
Echinococcus granulosus inositol monophosphatase 1 0.0121 0.01 0.01
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0041 0.0019 0.005
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0351
Loa Loa (eye worm) beta-lactamase 0.0156 0.0136 0.0204
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.0071 0.2622
Schistosoma mansoni ferritin 0.0026 0.0003 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Loa Loa (eye worm) hypothetical protein 0.0295 0.0277 0.0417
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0172 0.0152 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0126 0.0106 0.0159
Mycobacterium leprae conserved hypothetical protein 0.0042 0.002 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0156 0.0136 0.3388
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0153 0.2965
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0182 0.0162 0.0418
Brugia malayi Importin beta-1 subunit 0.0028 0.0006 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0126 0.0106 0.0106
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0019 0.0042
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0119 0.0098 0.0285
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0036 0.0014 0.0267
Trichomonas vaginalis CMGC family protein kinase 0.0075 0.0054 0.1336
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0067 0.0046 0.0127
Loa Loa (eye worm) hypothetical protein 0.0103 0.0082 0.0123
Trichomonas vaginalis inositol monophosphatase, putative 0.0121 0.01 0.2497
Trichomonas vaginalis chromobox protein, putative 0.0083 0.0061 0.1525
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0179 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Brugia malayi Inositol-1 0.0121 0.01 0.0151
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0057
Echinococcus granulosus lamin dm0 0.0033 0.001 0.001
Mycobacterium ulcerans monoamine oxidase 0.0041 0.0019 0.0049
Brugia malayi hypothetical protein 0.0474 0.0458 0.069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0108 0.0087 0.0252
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0076 0.0076
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0045 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0025 0.0487
Schistosoma mansoni ferritin 0.0026 0.0003 0.0008
Toxoplasma gondii ABC1 family protein 0.0156 0.0136 0.592
Brugia malayi ecdysteroid receptor 0.0126 0.0106 0.0159
Mycobacterium ulcerans hypothetical protein 0.0192 0.0172 0.0508
Trypanosoma brucei unspecified product 0.0126 0.0105 0.2022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.033 0.0312 0.0312
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0025 0.0067
Schistosoma mansoni cation-transporting ATPase 0.0031 0.0009 0.0024
Onchocerca volvulus Matrilysin homolog 0.2714 0.2734 0.4488
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0013 0.0197
Trichomonas vaginalis cation-transporting ATPase, putative 0.0036 0.0014 0.0351
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0068
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0015
Echinococcus granulosus neuropeptide s receptor 0.0573 0.0559 0.0559
Echinococcus granulosus dnaJ subfamily B 0.1626 0.1629 0.1629
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0036 0.0014 0.025
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.0054 0.2366
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0025 0.0058
Echinococcus multilocularis chromobox protein 1 0.0137 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0074 0.0052 0.0079
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0036 0.0014 0.0267
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0025 0.0487
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0417 0.0401 0.0401
Trypanosoma brucei DNA polymerase eta, putative 0.024 0.0221 0.4287
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0126 0.0106 0.0272
Brugia malayi Na,K-ATPase alpha subunit 0.0436 0.042 0.0632
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0157 0.0137 0.3413
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0528 0.0514 1
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0028 0.1225
Brugia malayi Pre-SET motif family protein 0.0032 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0228 0.0209 0.0538
Echinococcus multilocularis mitogen activated protein kinase 14 0.0138 0.0118 0.0118
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0179 0.0159 0.0159
Echinococcus granulosus ferritin 0.0026 0.0003 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0007 0.0018
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.006 0.0038 0.0097
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0041 0.0786
Brugia malayi orphan nuclear receptor NR2E1 0.006 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0051 0.0029 0.0044
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0075 0.0114
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0157 0.0137 0.2644
Treponema pallidum hypothetical protein 0.0057 0.0035 0.1211
Giardia lamblia DNA damage repair protein 0.0057 0.0035 0.0725
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0031 0.0009 0.0018
Leishmania major copper-transporting ATPase-like protein, putative 0.0031 0.0009 0.0172
Brugia malayi Smad1 0.0025 0.0002 0.0003
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.0054 0.1034
Brugia malayi Latrophilin receptor protein 2 0.0228 0.0209 0.0315
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0269 0.6722
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0156 0.0136 0.0204
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0153 0.2954
Echinococcus multilocularis chromobox protein 1 0.0137 0.0116 0.0116
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0126 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.0071 0.1768
Onchocerca volvulus 0.0054 0.0032 0.0053
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0042 0.002 0.0051
Echinococcus granulosus GPCR family 2 0.0228 0.0209 0.0209
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0313 0.0805
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0112 0.2798
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0075 0.0054 0.1035
Schistosoma mansoni hypothetical protein 0.0228 0.0209 0.0538
Brugia malayi conserved hypotetical protein 0.006 0.0038 0.0057
Schistosoma mansoni cation-transporting atpase worm 0.0031 0.0009 0.0024
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.0071 0.0071
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0614
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.0054 0.2007
Loa Loa (eye worm) matrix metalloproteinase 0.2714 0.2734 0.4116
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0059 0.0037 0.0095
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.012 0.035
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0722 0.071 0.1069
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0124 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0106 0.0159
Loa Loa (eye worm) transcription factor SMAD2 0.0361 0.0344 0.0517
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0041 0.0019 0.0718
Trypanosoma cruzi DNA damage repair protein, putative 0.0057 0.0035 0.0668
Trichomonas vaginalis aldehyde oxidase, putative 0.0352 0.0335 0.8361
Echinococcus granulosus acetylcholinesterase 0.0132 0.0112 0.0112
Toxoplasma gondii aldehyde dehydrogenase 0.0179 0.0159 0.6931
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0828 0.0819 0.0819
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.0191 0.3703
Trichomonas vaginalis CMGC family protein kinase 0.0075 0.0054 0.1336
Mycobacterium tuberculosis Conserved protein 0.0156 0.0136 0.0345
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0028 0.054
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0031 0.0009 0.0018
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0138 0.0118 0.2285
Schistosoma mansoni cpg binding protein 0.0114 0.0093 0.024
Schistosoma mansoni atpase class VI type 11c 0.0025 0.0003 0.0007
Trichomonas vaginalis helicase, putative 0.0026 0.0004 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0035 0.0653
Plasmodium falciparum flap endonuclease 1 0.0028 0.0005 0.0233
Schistosoma mansoni inositol monophosphatase 0.0121 0.01 0.0257
Plasmodium falciparum glutathione reductase 0.0057 0.0035 0.1538
Echinococcus granulosus calcium transporting atpase 0.0162 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0717 0.0705 0.1815
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0028 0.0042
Plasmodium vivax SET domain protein, putative 0.0032 0.0009 0.0345
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0341 0.0324 0.0487
Onchocerca volvulus 0.0156 0.0136 0.0223
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Loa Loa (eye worm) nuclear receptor NHR-67 0.006 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0132 0.0112 0.0168
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0007 0.001
Schistosoma mansoni hypothetical protein 0.3849 0.3886 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0106 0.0159
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0162 0.0142 0.2752
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0064 0.0042 0.1823
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0246 0.0227 0.0227
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0162 0.0142 0.0213
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0157 0.0137 0.2657
Echinococcus granulosus cation transporting ATPase 13A1 0.0031 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0032 0.0809
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0126 0.0106 0.0272
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0007 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0 0.0009
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0028 0.054
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0036 0.0014 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0106 0.0159
Treponema pallidum quinoline 2-oxidoreductase 0.0056 0.0034 0.116
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0029
Trypanosoma brucei calcium-transporting ATPase, putative 0.0036 0.0014 0.025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0313 0.0805
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0121 0.01 0.2497
Schistosoma mansoni apoferritin-2 0.0026 0.0003 0.0008
Trypanosoma brucei calcium-transporting ATPase, putative 0.0103 0.0082 0.1573
Echinococcus granulosus lamin 0.0033 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0015
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0028 0.0028
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0106 0.0272
Schistosoma mansoni polycystin 1-related 0.0357 0.034 0.0874
Brugia malayi nuclear hormone receptor 0.006 0.0038 0.0057
Echinococcus granulosus mitogen activated protein kinase 11 0.0138 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.033 0.0312 0.0804
Brugia malayi calcium ATPase 0.008 0.0059 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0271 0.6758
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0031 0.0009 0.0172
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0157 0.0137 0.3413
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0121 0.01 0.0291
Brugia malayi Cytochrome P450 family protein 0.0032 0.0009 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Leishmania major calcium motive p-type ATPase, putative 0.0162 0.0142 0.2752
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0012 0.0304
Echinococcus granulosus copper transporting ATPase 1 0.0031 0.0009 0.0009
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0067 0.0045 0.0045
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0 0.0009
Brugia malayi Heterochromatin protein 1 0.0137 0.0116 0.0175
Echinococcus granulosus acetylcholinesterase 0.0132 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0029 0.0564
Brugia malayi beta-lactamase family protein 0.0156 0.0136 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0126 0.0106 0.0159
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0159 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0054 0.0138
Brugia malayi Membrane calcium atpase protein 3 0.0162 0.0142 0.0213
Echinococcus multilocularis carbonic anhydrase 0.0248 0.0229 0.0229
Schistosoma mansoni terminal deoxycytidyl transferase 0.0182 0.0162 0.0418
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.003
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0013 0.0013
Leishmania major DNA polymerase eta, putative 0.024 0.0221 0.4297
Echinococcus granulosus nervana 2 0.0828 0.0819 0.0819
Mycobacterium ulcerans DNA polymerase IV 0.021 0.0191 0.0564
Loa Loa (eye worm) hypothetical protein 0.0022 0.0000000000020276 0.0000000000030524
Brugia malayi nuclear receptor NHR-88 0.006 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0025 0.0038
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Echinococcus multilocularis microtubule associated protein 2 0.2094 0.2104 0.2104
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0248 0.0229 0.0345
Loa Loa (eye worm) matrixin family protein 0.6563 0.6643 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0126 0.0106 0.0159
Schistosoma mansoni hypothetical protein 0.0082 0.0061 0.0157
Loa Loa (eye worm) hypothetical protein 0.0156 0.0136 0.0204
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0009 0.0009
Onchocerca volvulus 0.3849 0.3886 0.6379
Brugia malayi Calcitonin receptor-like protein seb-1 0.0722 0.071 0.1069
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0031 0.0009 0.0016
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0019 0.0029
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0157 0.0137 0.3249
Schistosoma mansoni chromobox protein 0.0137 0.0116 0.0299
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0156 0.0136 0.0204
Echinococcus multilocularis mitogen activated protein kinase 11 0.0138 0.0118 0.0118
Echinococcus multilocularis mitogen activated protein kinase 11 0.0138 0.0118 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0075 0.0054 0.1336
Echinococcus multilocularis expressed protein 0.0026 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0019 0.0718
Schistosoma mansoni phospholipid-transporting atpase 0.0036 0.0014 0.0036
Brugia malayi CHE-14 protein 0.0042 0.002 0.003
Schistosoma mansoni hypothetical protein 0.0022 0.0000000000020276 0.0000000000052178
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.017 0.4239
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0067 0.0046 0.0127
Echinococcus multilocularis musashi 0.0033 0.001 0.001
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0036 0.0014 0.0267
Trichomonas vaginalis cation-transporting ATPase, putative 0.0031 0.0009 0.0229
Brugia malayi isocitrate dehydrogenase 0.005 0.0028 0.0042
Brugia malayi hypothetical protein 0.0049 0.0027 0.0041
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0075 0.0054 0.1035
Echinococcus granulosus thyroid hormone receptor alpha 0.006 0.0038 0.0038
Echinococcus multilocularis acetylcholinesterase 0.0132 0.0112 0.0112
Brugia malayi ImpB/MucB/SamB family protein 0.024 0.0221 0.0332
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.011 0.0319
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0031 0.0009 0.0016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.011 0.0277
Loa Loa (eye worm) hypothetical protein 0.0178 0.0158 0.0237
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.423 0.4273 0.4273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0026 0.0656
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.0071 0.3091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0106 0.0106
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0046 0.0024 0.0609
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0000000000020276 0.000000000088471
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0269 0.6527
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0828 0.0819 0.0819
Loa Loa (eye worm) hypothetical protein 0.0076 0.0054 0.0082
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0157 0.0137 0.2644
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0041 0.0019 0.0019
Plasmodium falciparum thioredoxin reductase 0.0057 0.0035 0.1538
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0126 0.0106 0.0106
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0071 0.0071
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0436 0.042 0.1081
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0133 0.0112 0.0112
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0045 0.0115
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0182 0.0162 0.0162
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0019 0.0048
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0025 0.0633
Echinococcus granulosus tar DNA binding protein 0.0133 0.0113 0.0113
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0126 0.0106 0.0272
Entamoeba histolytica hypothetical protein 0.0023 0 0.0009
Echinococcus multilocularis nervana 2 0.0828 0.0819 0.0819
Schistosoma mansoni tsg101-related 0.0062 0.004 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.033 0.0313 0.0471
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.0071 0.1768
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0006 0.0006
Echinococcus multilocularis nuclear receptor nhr 48 0.006 0.0038 0.0038
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.0282 0.0424
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0019 0.0706
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0214 0.5344
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0038 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0014 0.0021
Schistosoma mansoni chromobox protein 0.0137 0.0116 0.0299
Brugia malayi chromobox protein homolog 3 0.0077 0.0055 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0126 0.0106 0.0159
Schistosoma mansoni hypothetical protein 0.0717 0.0705 0.1815
Echinococcus granulosus chromobox protein 1 0.0137 0.0116 0.0116
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0352 0.0335 0.8361
Brugia malayi latrophilin 2 splice variant baaae 0.0493 0.0478 0.072
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.008 0.0059 0.0088
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0231 0.0212 0.051
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0172 0.0152 0.0152
Schistosoma mansoni carbonic anhydrase 0.0248 0.0229 0.059
Schistosoma mansoni hypothetical protein 0.0228 0.0209 0.0538
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0031 0.0009 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.002 0.0504
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.003
Loa Loa (eye worm) heterochromatin protein 1 0.0137 0.0116 0.0175
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0313 0.0295 0.0295
Plasmodium falciparum calcium-transporting ATPase 0.0162 0.0142 0.6178
Schistosoma mansoni transient receptor potential channel 0.0063 0.0042 0.0107
Echinococcus multilocularis acetylcholinesterase 0.0132 0.0112 0.0112
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Loa Loa (eye worm) hypothetical protein 0.0264 0.0245 0.0369
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0147 0.0126 0.2994
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.0458 0.0458
Echinococcus multilocularis snurportin 1 0.03 0.0282 0.0282
Echinococcus multilocularis mitogen activated protein kinase 3 0.0075 0.0054 0.0054
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0028 0.1225
Brugia malayi MH1 domain containing protein 0.0025 0.0002 0.0003
Plasmodium falciparum protoporphyrinogen oxidase 0.0041 0.0019 0.0846
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0007 0.0007
Echinococcus granulosus phospholipid transporting ATPase IF 0.0036 0.0014 0.0014
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0157 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0106 0.0085 0.0128
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 0.0158 0.0259
Trichomonas vaginalis importin beta-1, putative 0.0023 0 0.0009
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0028 0.0072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0009 0.0406
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0157 0.0137 0.2657
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0138 0.0118 0.2285
Schistosoma mansoni tsg101-related 0.0062 0.004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0248 0.0229 0.0345
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.0313 0.0313
Echinococcus granulosus ecdysone induced protein 78C 0.0126 0.0106 0.0106
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0828 0.0819 0.0819
Trichomonas vaginalis CAMK family protein kinase 0.0417 0.0401 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0009 0.0024
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.006 0.0038 0.0038
Schistosoma mansoni flap endonuclease-1 0.0025 0.0003 0.0007
Plasmodium falciparum importin beta, putative 0.0028 0.0006 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0136 0.2637
Echinococcus granulosus phospholipid transporting atpase ih 0.0036 0.0014 0.0014
Brugia malayi calcium ATPase 0.0082 0.006 0.0091
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0009 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0054 0.2366
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.0348 0.6762
Trichomonas vaginalis CAMK family protein kinase 0.0213 0.0193 0.4827
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0113 0.029
Brugia malayi MH2 domain containing protein 0.0361 0.0344 0.0517
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0228 0.0209 0.0209
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0231 0.0212 0.0628
Schistosoma mansoni smad1 5 8 and 0.0025 0.0002 0.0006
Brugia malayi TAR-binding protein 0.0133 0.0113 0.017
Schistosoma mansoni lamin 0.0033 0.001 0.0027
Echinococcus granulosus cpg binding protein 0.0121 0.01 0.01
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0159 0.0467
Brugia malayi SWIRM domain containing protein 0.0041 0.0019 0.0029
Echinococcus granulosus Na:K ATPase alpha subunit 0.0426 0.041 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0004 0.0088
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0172 0.0152 0.0446
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0528 0.0514 0.0773
Schistosoma mansoni transmemberane protein 0.0828 0.0819 0.2106
Plasmodium falciparum histone acetyltransferase GCN5 0.0084 0.0063 0.2751
Brugia malayi E1-E2 ATPase family protein 0.0105 0.0084 0.0127
Brugia malayi jmjC domain containing protein 0.006 0.0038 0.0057
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0013 0.002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0124 0.0364
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0000000000020276 0.000000000050622
Loa Loa (eye worm) hypothetical protein 0.0059 0.0037 0.0056
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0362 0.0345 0.1026
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0031 0.0009 0.0401
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0025 0.0487
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0112 0.2798

Activities

Activity type Activity value Assay description Source Reference
ED10 (functional) = 0.17 ug kg-1 Dose producing 10% decrease in heart rate of anesthetized spontaneously hypertensive rats (SHR's) ChEMBL. 1495019
ED30 (functional) = 0.53 ug kg-1 Dose producing 30% decrease in blood pressure of anesthetized spontaneously hypertensive rats (SHR's) ChEMBL. 1495019
IC50 (binding) = 0.005 uM Displacement of [3H]-DPCPX from adenosine A1 receptor of rat cortical membranes without GTP ChEMBL. 15084123
IC50 (binding) = 0.125 uM Displacement of [3H]-DPCPX from adenosine A1 receptor of rat cortical membranes with GTP ChEMBL. 15084123
Ki (binding) = 0.76 nM Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]-cyclohexyladenosine as radioligand. ChEMBL. 1495019
Ki (binding) = 1.3 nM Adenosine A1 receptor binding was measured in adenosine deaminase (ADA) pretreated rat cortical membranes using [3H]-cyclohexyladenosine in the presence of 2-chloroadenosine ChEMBL. 2362269
Ki (binding) = 336 nM Binding affinity against adenosine A2 receptor from rat striatum using [3H]-NECA as radioligand. ChEMBL. 1495019
Ki (binding) = 636 nM Binding to Adenosine A2 receptor was measured in ADA-pretreated rat striatal membranes using [3H]-CGS- 21680 ChEMBL. 2362269
Ratio (binding) = 0.002 Ratio of A1-receptor binding to that of A2-receptor binding ChEMBL. 2362269
Ratio (binding) = 22.8 Binding affinity against adenosine A1 receptor without GTP ChEMBL. 15084123
Selectivity (binding) = 0.002 Selectivity determined as Ratio of Ki(nM) of A1 adenosine receptor to the Ki(nM) of A2 adenosine receptor ChEMBL. 1495019

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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