Detailed information for compound 886756

Basic information

Technical information
  • TDR Targets ID: 886756
  • Name: ethyl 2-[(3,4-dichlorophenyl)sulfonylamino]-3 -phenylpropanoate
  • MW: 402.292 | Formula: C17H17Cl2NO4S
  • H donors: 1 H acceptors: 3 LogP: 4.42 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C(NS(=O)(=O)c1ccc(c(c1)Cl)Cl)Cc1ccccc1
  • InChi: 1S/C17H17Cl2NO4S/c1-2-24-17(21)16(10-12-6-4-3-5-7-12)20-25(22,23)13-8-9-14(18)15(19)11-13/h3-9,11,16,20H,2,10H2,1H3
  • InChiKey: YGWUVWGWYDHBDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 2-[(3,4-dichlorophenyl)sulfonylamino]-3-phenyl-propanoate
  • 2-[(3,4-dichlorophenyl)sulfonylamino]-3-phenylpropanoic acid ethyl ester
  • 2-[(3,4-dichlorophenyl)sulfonylamino]-3-phenyl-propionic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK protein kinase 0.0708 0.3121 0.3376
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0234 0.068 0.0718
Schistosoma mansoni tyrosine kinase 0.0906 0.4141 0.7108
Trichomonas vaginalis AGC family protein kinase 0.0484 0.1968 0.5204
Schistosoma mansoni rap gtpase-activating protein 0.0197 0.0491 0.0802
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0467 0.1877 0.2253
Brugia malayi cell division control protein 2 homolog 0.0243 0.0728 0.0765
Brugia malayi Protein kinase domain containing protein 0.0172 0.0361 0.0364
Echinococcus multilocularis TGF beta receptor type 1 0.0141 0.0203 0.0215
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Entamoeba histolytica PH domain containing protein kinase, putative 0.025 0.0761 0.2017
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0263 0.083 0.2197
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0196 0.0485 0.05
Schistosoma mansoni serine/threonine protein kinase 0.0598 0.2555 0.4367
Schistosoma mansoni cell adhesion molecule 0.0247 0.0745 0.124
Entamoeba histolytica protein kinase, putative 0.0277 0.0903 0.2394
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0723 0.1895
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0178 0.0391 0.0444
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0334 0.1195 0.1423
Trypanosoma cruzi casein kinase, putative 0.0223 0.0624 0.2639
Loa Loa (eye worm) hypothetical protein 0.017 0.0352 0.036
Plasmodium vivax tyrosine kinase-like protein, putative 0.0168 0.0339 0.1702
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0467 0.1877 0.2253
Echinococcus multilocularis neuroglian 0.0225 0.0636 0.0742
Echinococcus multilocularis cyclin dependent kinase 1 0.0243 0.0728 0.0855
Trichomonas vaginalis STE family protein kinase 0.0107 0.0027 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.044 0.1739 0.4596
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0178 0.0391 0.0366
Echinococcus granulosus cyclin dependent kinase 9 0.0116 0.007 0.0044
Schistosoma mansoni protein kinase 0.0391 0.149 0.2528
Echinococcus granulosus serine:threonine kinase SAD 1 0.0185 0.0426 0.0401
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0783
Echinococcus multilocularis protein kinase shaggy 0.0263 0.083 0.0979
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Entamoeba histolytica serine/threonine protein kinase, putative 0.0546 0.2288 0.6065
Brugia malayi Protein kinase domain containing protein 0.0243 0.0728 0.0765
Brugia malayi hypothetical protein 0.045 0.1793 0.1925
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Trypanosoma cruzi casein kinase, putative 0.0223 0.0624 0.2639
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0519 0.215 0.2318
Onchocerca volvulus 0.0153 0.0261 0.0446
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0723 0.0764
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.025 0.0763 0.0808
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0425 0.1665 0.1996
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.189 0.9204 1
Echinococcus multilocularis NCK adaptor protein 0.0195 0.0477 0.0549
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Echinococcus granulosus NCK adaptor protein 0.0189 0.0449 0.0424
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0377 0.1546
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0263 0.083 0.0881
Echinococcus granulosus Glutaredoxin protein 5 0.0391 0.149 0.1468
Brugia malayi bone morphogenetic protein type 1 receptor 0.0171 0.0356 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0466 0.0758
Loa Loa (eye worm) thyroid receptor interactor 0.0226 0.064 0.0674
Schistosoma mansoni serine/threonine protein kinase 0.0594 0.2531 0.4326
Brugia malayi serine/threonine protein kinase 6 0.0242 0.0723 0.0759
Schistosoma mansoni tyrosine kinase 0.1114 0.5209 0.8952
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0624 0.1031
Plasmodium falciparum protein kinase, putative 0.0173 0.0367 0.1855
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.012 0.0095 0.0084
Echinococcus granulosus protein kinase c iota type 0.0682 0.2987 0.2969
Plasmodium falciparum serine/threonine protein kinase KIN 0.0185 0.0426 0.2173
Echinococcus multilocularis serine:threonine protein kinase N2 0.0685 0.3 0.3621
Plasmodium falciparum serine/threonine protein kinase 0.0172 0.0361 0.1819
Echinococcus granulosus casein kinase I gamma 0.0432 0.1701 0.1679
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0115 0.0065 0.0064
Echinococcus granulosus tyrosine protein kinase Fyn 0.0467 0.1877 0.1856
Giardia lamblia Kinase, NEK 0.0278 0.0907 0.3891
Schistosoma mansoni serine/threonine protein kinase 0.0516 0.2131 0.3634
Brugia malayi Casein kinase II, alpha chain 0.0206 0.0536 0.0555
Entamoeba histolytica SH2 domain containing protein 0.0115 0.0065 0.0171
Echinococcus multilocularis growth factor receptor bound protein 2 0.0189 0.0449 0.0514
Echinococcus multilocularis protein tyrosine kinase 0.1114 0.5209 0.631
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.1665 0.283
Echinococcus granulosus defective proboscis extension response 0.0176 0.038 0.0355
Echinococcus multilocularis cyclin dependent kinase 9 0.0123 0.0109 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.1729 0.294
Trichomonas vaginalis CMGC family protein kinase 0.0243 0.0728 0.191
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0391 0.149 0.16
Echinococcus multilocularis myosin iiia 0.0175 0.0377 0.0427
Echinococcus granulosus TGF beta receptor type 1 0.0141 0.0203 0.0177
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Schistosoma mansoni protein kinase 0.0206 0.0536 0.0879
Echinococcus multilocularis casein kinase I alpha 0.0223 0.0624 0.0728
Schistosoma mansoni protein kinase 0.0223 0.0624 0.1031
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0115 0.0065 0.0039
Schistosoma mansoni protein kinase C mu 0.0448 0.1784 0.3034
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Echinococcus granulosus activated cdc42 kinase 1 0.0262 0.0826 0.0801
Entamoeba histolytica protein kinase , putative 0.0242 0.0723 0.1915
Trichomonas vaginalis STE family protein kinase 0.0178 0.0391 0.1013
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0216 0.0584 0.0613
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.0732 0.1919
Trypanosoma cruzi casein kinase II, putative 0.0206 0.0536 0.225
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.0391 0.0444
Loa Loa (eye worm) STAT protein 0.0115 0.0065 0.0047
Entamoeba histolytica protein kinase, putative 0.0423 0.1653 0.4382
Brugia malayi protein-tyrosine kinase 0.0392 0.1493 0.1598
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.069 0.1809
Loa Loa (eye worm) SH2 domain-containing protein 0.0115 0.0065 0.0047
Brugia malayi Protein kinase domain containing protein 0.0216 0.0587 0.0611
Echinococcus granulosus protein kinase C gamma type 0.0507 0.2087 0.2066
Schistosoma mansoni serine/threonine protein kinase 0.0519 0.2147 0.3662
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0484 0.1968 0.1947
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0392 0.1493 0.1471
Loa Loa (eye worm) hypothetical protein 0.0238 0.07 0.0739
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0232 0.0669 0.07
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0423 0.1653 0.4341
Giardia lamblia Kinase, CAMK CAMKL 0.0192 0.0465 0.1936
Echinococcus multilocularis tyrosine protein kinase shark 0.0643 0.2786 0.336
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0313 0.1087 0.4688
Loa Loa (eye worm) TK/FER protein kinase 0.0823 0.3711 0.4019
Trypanosoma cruzi polo-like protein kinase, putative 0.0546 0.2288 1
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus multilocularis SHC transforming protein 3 0.0115 0.0065 0.0047
Brugia malayi Protein kinase domain containing protein 0.0581 0.2466 0.2659
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0197 0.0491 0.2053
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0463 0.186 1
Schistosoma mansoni tyrosine kinase 0.1231 0.5815 1
Giardia lamblia Kinase, PLK 0.0546 0.2288 1
Onchocerca volvulus 0.0216 0.0587 0.1071
Onchocerca volvulus 0.0394 0.1506 0.2828
Brugia malayi Furin-like cysteine rich region family protein 0.1231 0.5815 0.6308
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.1572 0.2669
Toxoplasma gondii AGC kinase 0.0232 0.0669 0.1756
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0704 0.117
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0313 0.1087 0.1161
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0446 0.1773 0.7721
Onchocerca volvulus Serine\/threonine kinase homolog 0.0334 0.1195 0.2233
Schistosoma mansoni serine/threonine protein kinase 0.0457 0.1829 0.3112
Schistosoma mansoni vam6/vps39 related 0.0197 0.0491 0.0802
Brugia malayi Immunoglobulin I-set domain containing protein 0.0153 0.0261 0.0256
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0236 0.069 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0344 0.0547
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0296 0.0999 0.1184
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.045 0.1793 0.193
Brugia malayi hypothetical protein 0.0216 0.0587 0.0611
Entamoeba histolytica casein kinase 1, putative 0.0223 0.0624 0.1654
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0367 0.1504
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0115 0.0065 0.0047
Entamoeba histolytica protein kinase, putative 0.0835 0.3773 1
Leishmania major protein kinase, putative 0.0313 0.1087 0.4688
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0891 0.1492
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0232 0.0669 0.2838
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Schistosoma mansoni tensin 0.0115 0.0065 0.0064
Echinococcus granulosus cGMP dependent protein kinase 1 0.0275 0.0891 0.0867
Schistosoma mansoni tyrosine kinase 0.0163 0.0316 0.0499
Echinococcus multilocularis twitchin 0.0121 0.01 0.009
Echinococcus multilocularis transfer RNA-Thr 0.0262 0.0826 0.0973
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0423 0.1653 0.1777
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Plasmodium falciparum serine/threonine protein kinase, putative 0.0242 0.0723 0.3793
Schistosoma mansoni protein kinase 0.0242 0.0723 0.1201
Brugia malayi Protein kinase domain containing protein 0.0334 0.1195 0.1273
Echinococcus granulosus SH2 domain containing protein 7 0.0115 0.0065 0.0039
Loa Loa (eye worm) hypothetical protein 0.0109 0.0035 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Echinococcus granulosus serine:threonine protein kinase TAO1 0.045 0.1793 0.1772
Schistosoma mansoni serine/threonine kinase 0.0425 0.1665 0.283
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.1418 0.2403
Brugia malayi STAT protein, DNA binding domain containing protein 0.0115 0.0065 0.0042
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0296 0.0996 0.1181
Brugia malayi serine/threonine-protein kinase 6 0.0242 0.0723 0.0759
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0173 0.0367 0.093
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0395 0.1506 0.3977
Toxoplasma gondii aurora kinase 0.0242 0.0723 0.1903
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0446 0.1773 0.1908
Trichomonas vaginalis CK1 family protein kinase 0.0223 0.0624 0.1633
Onchocerca volvulus 0.0216 0.0587 0.1071
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0223 0.0624 0.0657
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0228 0.0347
Trypanosoma cruzi cdc2-related kinase 1 0.0243 0.0728 0.3101
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus granulosus cyclin dependent kinase 7 0.0146 0.0228 0.0203
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0216 0.0584 0.2464
Schistosoma mansoni tensin-related 0.0115 0.0065 0.0064
Echinococcus granulosus roundabout 2 0.012 0.0095 0.0069
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0723 0.0764
Schistosoma mansoni ephrin receptor 0.023 0.0657 0.1087
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Onchocerca volvulus 0.0412 0.1596 0.3
Schistosoma mansoni serine/threonine protein kinase 0.0534 0.2226 0.3799
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0173 0.0367 0.1504
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0115 0.0065 0.0047
Echinococcus granulosus myotubularin protein 13 0.0109 0.0035 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0197 0.0491 0.1239
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0484 0.1968 0.2364
Giardia lamblia Kinase, NEK 0.0278 0.0907 0.3891
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0711 0.3135 0.3388
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0903 0.4124 0.4468
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1018 0.4715 0.4701
Schistosoma mansoni hypothetical protein 0.0115 0.0065 0.0064
Echinococcus multilocularis contactin neuroglian septate junction protein 0.012 0.0095 0.0084
Echinococcus multilocularis cyclin dependent kinase 5 0.0243 0.0728 0.0855
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Trichomonas vaginalis STE family protein kinase 0.0135 0.0168 0.042
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0197 0.0491 0.0566
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0783
Loa Loa (eye worm) hypothetical protein 0.0172 0.0359 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Loa Loa (eye worm) hypothetical protein 0.0377 0.1414 0.1517
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Loa Loa (eye worm) protein kinase domain-containing protein 0.0432 0.1701 0.1829
Trypanosoma brucei cdc2-related kinase 3 0.0243 0.0728 0.1872
Echinococcus granulosus serine:threonine protein kinase 0.0234 0.068 0.0656
Echinococcus multilocularis casein kinase I alpha 0.0223 0.0624 0.0728
Echinococcus multilocularis protein kinase c iota type 0.0682 0.2987 0.3605
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0425 0.1665 0.1996
Echinococcus multilocularis calcium activated potassium channel 0.0276 0.0894 0.1056
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0184 0.0421 0.0481
Leishmania major casein kinase II, putative 0.0206 0.0536 0.225
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0377 0.1418 0.1521
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0438 0.1729 0.1708
Schistosoma mansoni nephrin 0.0257 0.0797 0.133
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Loa Loa (eye worm) AGC/PKG protein kinase 0.0275 0.0891 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.1591 0.2702
Brugia malayi Protein kinase domain containing protein 0.0216 0.0587 0.0611
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0466 0.1876 0.202
Echinococcus granulosus protein kinase c epsilon type 0.0519 0.2147 0.2126
Echinococcus multilocularis cyclin dependent kinase 9 0.0116 0.007 0.0053
Echinococcus granulosus contactin 0.012 0.0095 0.0069
Brugia malayi Protein kinase domain containing protein 0.0407 0.1572 0.1685
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0215 0.0584 0.0559
Echinococcus granulosus fibroblast growth factor receptor 4 0.0498 0.2039 0.2018
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0244 0.0732 0.3842
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0429 0.1116
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Echinococcus granulosus tyrosine kinase 0.0216 0.0587 0.0563
Echinococcus granulosus dual specificity protein kinase clk2 0.0313 0.1087 0.1064
Trypanosoma brucei polo-like protein kinase 0.0546 0.2288 0.6036
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0244 0.0732 0.0707
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0313 0.1087 0.4688
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0357 0.1315 0.1409
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0242 0.0723 0.3793
Trypanosoma cruzi cdc2-related kinase 3 0.0243 0.0728 0.3101
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0235 0.0358
Echinococcus multilocularis cyclin dependent kinase 0.0243 0.0728 0.0855
Plasmodium falciparum casein kinase 1 0.0223 0.0624 0.3255
Toxoplasma gondii AGC kinase 0.0817 0.3681 1
Brugia malayi Protein kinase domain containing protein 0.1206 0.5683 0.6164
Trichomonas vaginalis STE family protein kinase 0.0178 0.0391 0.1013
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.1729 0.294
Schistosoma mansoni cell adhesion molecule 0.012 0.0095 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.068 0.1782
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0185 0.0426 0.1063
Schistosoma mansoni protein kinase 0.1018 0.4715 0.8098
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0407 0.1572 0.155
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0367 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0467 0.1877 0.2253
Schistosoma mansoni protein kinase 0.0178 0.0391 0.0628
Entamoeba histolytica protein kinase, putative 0.0284 0.0936 0.2481
Echinococcus multilocularis nervana 2 0.0391 0.149 0.1783
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0232 0.0669 0.2838
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.012 0.0095 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0095 0.0075
Echinococcus granulosus tyrosine kinase 0.0392 0.1493 0.1471
Echinococcus granulosus nervana 2 0.0391 0.149 0.1468
Giardia lamblia Kinase, CMGC CDK 0.0243 0.0728 0.3101
Giardia lamblia Aurora kinase 0.0242 0.0723 0.3075
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0236 0.069 0.0808
Schistosoma mansoni hypothetical protein 0.0204 0.0524 0.0858
Schistosoma mansoni serine/threonine protein kinase 0.096 0.4416 0.7583
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0115 0.0065 0.0047
Schistosoma mansoni ephrin receptor 0.0133 0.0159 0.0227
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Trypanosoma cruzi p21-activated kinase 3, putative 0.0115 0.0068 0.0179
Brugia malayi casein kinase I 0.0223 0.0624 0.0651
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.0542 0.0561
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0284 0.0936 0.402
Trichomonas vaginalis STE family protein kinase 0.0216 0.0584 0.1528
Echinococcus multilocularis casein kinase ii subunit alpha 0.0206 0.0536 0.0621
Loa Loa (eye worm) hypothetical protein 0.047 0.1897 0.2043
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0448 0.1784 0.1915
Brugia malayi Protein kinase domain containing protein 0.013 0.0142 0.0126
Entamoeba histolytica protein kinase domain containing protein 0.0173 0.0367 0.0974
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.2853 0.4882
Schistosoma mansoni SH2A 0.0115 0.0065 0.0064
Echinococcus multilocularis casein kinase I alpha 0.0223 0.0624 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0232 0.0669 0.1756
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus granulosus cyclin dependent kinase 5 0.0243 0.0728 0.0704
Echinococcus granulosus cyclin dependent kinase 19 0.0199 0.0498 0.0474
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0448 0.1784 0.192
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0291 0.0971 0.1631
Echinococcus multilocularis serine:threonine protein kinase N2 0.0425 0.1665 0.1996
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0169 0.0344 0.0319
Brugia malayi protein unc-22 0.0153 0.0261 0.0256
Trypanosoma brucei rac serine-threonine kinase, putative 0.0835 0.3773 1
Trichomonas vaginalis AGC family protein kinase 0.0433 0.1705 0.4505
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Plasmodium vivax glycogen synthase kinase 3, putative 0.0263 0.083 0.438
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0115 0.0065 0.007
Leishmania major protein kinase, putative 0.0173 0.0367 0.1504
Echinococcus granulosus casein kinase i 0.0223 0.0624 0.0599
Brugia malayi Protein kinase domain containing protein 0.0169 0.0344 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0794 0.3564 0.611
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0223 0.0624 0.0657
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0113 0.0055 0.0121
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0115 0.0068 0.0051
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0244 0.0732 0.0859
Schistosoma mansoni tyrosine kinase 0.0906 0.4141 0.7108
Echinococcus multilocularis expressed protein 0.0172 0.0361 0.0408
Onchocerca volvulus 0.0216 0.0587 0.1071
Echinococcus multilocularis SH2 motif 0.0115 0.0065 0.0047
Loa Loa (eye worm) gastrulation defective protein 1 0.0127 0.0129 0.0117
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0376 0.141 0.1387
Brugia malayi Serine/threonine-protein kinase SULU 0.045 0.1793 0.1925
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0794 0.3564 0.4307
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0631 0.2723 0.3283
Loa Loa (eye worm) AGC/NDR protein kinase 0.0425 0.1665 0.1791
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0243 0.0728 0.077
Giardia lamblia Kinase, CMGC DYRK 0.0284 0.0936 0.402
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Trypanosoma cruzi aurora B kinase, putative 0.0242 0.0723 0.3075
Echinococcus granulosus casein kinase I delta 0.0223 0.0624 0.0599
Entamoeba histolytica cell division protein kinase 2, putative 0.0251 0.0768 0.2035
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0197 0.0491 0.0467
Onchocerca volvulus 0.0185 0.0429 0.0769
Entamoeba histolytica protein kinase, putative 0.0817 0.3681 0.9756
Loa Loa (eye worm) TK/EPH protein kinase 0.0265 0.0837 0.0889
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0148 0.0235 0.0254
Echinococcus multilocularis rho associated protein kinase 0.0656 0.2853 0.3441
Echinococcus granulosus insulin receptor 0.0906 0.4141 0.4126
Brugia malayi Tyrosine-protein kinase abl-1 0.0256 0.0794 0.0836
Loa Loa (eye worm) CDC7 protein kinase 0.0185 0.0429 0.0445
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0244 0.0732 0.1927
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus granulosus titin 0.0153 0.0261 0.0236
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0269 0.0861 0.0837
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0242 0.0723 0.1915
Loa Loa (eye worm) hypothetical protein 0.0197 0.0491 0.0512
Loa Loa (eye worm) casein kinase 0.0361 0.1331 0.1427
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0216 0.0584 0.2464
Brugia malayi STE20-like kinase MST 0.0519 0.215 0.2314
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0361 0.089
Brugia malayi Temporarily assigned gene name protein 59 0.0197 0.0491 0.0507
Plasmodium falciparum cGMP-dependent protein kinase 0.0275 0.0891 0.4713
Entamoeba histolytica p21-activated kinase 0.0196 0.0483 0.128
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Entamoeba histolytica protein kinase, putative 0.0178 0.0391 0.1036
Schistosoma mansoni suppressor of cytokine signaling 0.0115 0.0065 0.0064
Onchocerca volvulus 0.0216 0.0587 0.1071
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0594 0.2531 0.305
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0243 0.0728 0.077
Brugia malayi Protein kinase domain containing protein 0.0425 0.1665 0.1786
Echinococcus granulosus titin 0.0153 0.0261 0.0236
Echinococcus granulosus SHC transforming protein 3 0.0115 0.0065 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.1701 0.2891
Schistosoma mansoni tyrosine kinase 0.0528 0.2196 0.3747
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0263 0.083 0.355
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.005 0.0133
Echinococcus multilocularis SH2 motif 0.0115 0.0065 0.0047
Echinococcus granulosus SH2 motif 0.0115 0.0065 0.0039
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0242 0.0723 0.1915
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0232 0.0669 0.3501
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0115 0.0065 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.069 0.1809
Echinococcus granulosus roundabout 2 0.012 0.0095 0.0069
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0244 0.0732 0.0774
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0244 0.0732 0.3842
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0284 0.0936 0.0997
Giardia lamblia Kinase, CMGC CLK 0.0313 0.1087 0.4688
Trypanosoma brucei protein kinase, putative 0.0181 0.0407 0.1013
Schistosoma mansoni vesicular amine transporter 0.0176 0.038 0.061
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0131 0.015 0.014
Trypanosoma brucei protein kinase, putative 0.0263 0.083 0.2143
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.012 0.0095 0.0084
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0546 0.2288 0.2268
Schistosoma mansoni serine/threonine-protein kinase 0.0481 0.1952 0.3325
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.012 0.0095 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0466 0.1876 0.4959
Loa Loa (eye worm) TK/ROR protein kinase 0.0151 0.0253 0.0252
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0068 0.007
Plasmodium vivax unspecified product 0.0206 0.0536 0.2775
Trypanosoma cruzi casein kinase, putative 0.0223 0.0624 0.2639
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0308 0.1058 0.1129
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0891 0.1492
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus multilocularis casein kinase I delta 0.0223 0.0624 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0429 0.0695
Schistosoma mansoni protein kinase 0.0216 0.0584 0.0962
Schistosoma mansoni growth factor receptor-bound protein 0.0189 0.0449 0.0728
Onchocerca volvulus 0.0115 0.0065 0.007
Brugia malayi map kinase activated protein kinase protein 2 0.0794 0.3564 0.3855
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.01 0.0125
Entamoeba histolytica protein kinase, putative 0.0835 0.3773 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0107 0.0027 0.0073
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0197 0.0491 0.2053
Brugia malayi Protein kinase domain containing protein 0.1206 0.5683 0.6164
Schistosoma mansoni protein kinase 0.0713 0.3147 0.5391
Echinococcus granulosus tyrosine protein kinase Fyn 0.0467 0.1877 0.1856
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0278 0.0907 0.2408
Echinococcus multilocularis mitogen activated protein kinase 14 0.0446 0.1773 0.2126
Echinococcus multilocularis activated cdc42 kinase 1 0.0262 0.0826 0.0973
Echinococcus multilocularis neuroglian 0.012 0.0095 0.0084
Schistosoma mansoni atypical protein kinase C 0.0694 0.305 0.5222
Echinococcus multilocularis PAK box P21 Rho binding 0.0135 0.0168 0.0172
Brugia malayi Protein kinase c protein 2 0.0245 0.0734 0.0771
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0206 0.0536 0.0561
Trypanosoma brucei SNF1-related protein kinases, putative 0.0185 0.0426 0.1063
Toxoplasma gondii CMGC kinase, CK2 family 0.0206 0.0536 0.1392
Brugia malayi Protein kinase domain containing protein 0.1126 0.5271 0.5715
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0594 0.2531 0.2512
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0313 0.1087 0.4688
Echinococcus multilocularis myotubularin protein 13 0.0109 0.0035 0.0011
Echinococcus multilocularis dual specificity 0.0423 0.1653 0.1981
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0711 0.3135 0.3391
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.012 0.0095 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Brugia malayi putative serine/threonine kinase SADA gamma 0.0185 0.0426 0.0435
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0426 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0806 0.2118
Echinococcus multilocularis epidermal growth factor receptor 0.1231 0.5815 0.7048
Schistosoma mansoni serine/threonine protein kinase 0.045 0.1793 0.3051
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0313 0.1087 0.2829
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0244 0.0732 0.0707
Echinococcus multilocularis tyrosine kinase 0.0216 0.0587 0.0683
Onchocerca volvulus 0.0128 0.0134 0.0203
Echinococcus multilocularis 0.0241 0.0717 0.0842
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0824 0.3718 0.3701
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Plasmodium falciparum calcium-dependent protein kinase 1 0.0244 0.0732 0.3842
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0244 0.0732 0.1927
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Loa Loa (eye worm) AGC/PKA protein kinase 0.0232 0.0669 0.0706
Loa Loa (eye worm) SRC-1 0.0467 0.1877 0.2021
Schistosoma mansoni serine/threonine protein kinase 0.0711 0.3135 0.537
Echinococcus granulosus mitogen activated protein kinase 0.0173 0.0367 0.0342
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0243 0.0728 0.0855
Brugia malayi Protein kinase domain containing protein 0.0401 0.1538 0.1647
Brugia malayi hypothetical protein 0.0115 0.0065 0.0042
Loa Loa (eye worm) hypothetical protein 0.0265 0.0839 0.0891
Trichomonas vaginalis STE family protein kinase 0.0178 0.0391 0.1013
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0546 0.2288 1
Trichomonas vaginalis STE family protein kinase 0.0175 0.0377 0.0976
Loa Loa (eye worm) TK/FAK protein kinase 0.1126 0.5271 0.5717
Entamoeba histolytica casein kinase, putative 0.0206 0.0536 0.1421
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0027 0.0048
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0463 0.186 0.8107
Echinococcus multilocularis epidermal growth factor receptor 0.0815 0.3672 0.4438
Trichomonas vaginalis STE family protein kinase 0.0216 0.0584 0.1528
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0012 0.0006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0244 0.0732 0.0859
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.047 0.1895 0.2041
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0594 0.2531 0.2734
Echinococcus multilocularis tensin 0.0115 0.0065 0.0047
Echinococcus granulosus raf serine:threonine protein kinase 0.0193 0.0466 0.0441
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0171 0.0356 0.0364
Echinococcus multilocularis roundabout 2 0.012 0.0095 0.0084
Echinococcus granulosus tyrosine protein kinase Src42A 0.0296 0.0999 0.0975
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0185 0.0426 0.0441
Echinococcus multilocularis casein kinase I delta 0.0223 0.0624 0.0728
Brugia malayi SRC-1 0.0467 0.1877 0.2016
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.0391 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0598 0.2555 0.4367
Loa Loa (eye worm) IKK protein kinase 0.0968 0.4458 0.4832
Trichomonas vaginalis CMGC family protein kinase 0.0313 0.1087 0.2864
Entamoeba histolytica protein kinase, putative 0.0148 0.0235 0.0622
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0175 0.0377 0.0999
Loa Loa (eye worm) hypothetical protein 0.0232 0.0669 0.0706
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0179 0.0399 0.0642
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0429 0.1116
Schistosoma mansoni protein kinase 0.0171 0.0356 0.0567
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0115 0.0065 0.0039
Echinococcus multilocularis dual specificity 0.0284 0.0936 0.1108
Giardia lamblia Kinase, CK1 Casein kinase 0.0223 0.0624 0.2639
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Trichomonas vaginalis STE family protein kinase 0.0178 0.0391 0.1013
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0423 0.1653 0.7192
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Trichomonas vaginalis CK1 family protein kinase 0.0223 0.0624 0.1633
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0168 0.0339 0.1702
Echinococcus granulosus neuroglian 0.012 0.0095 0.0069
Loa Loa (eye worm) TK/ABL protein kinase 0.0631 0.2723 0.2942
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0467 0.1877 0.2253
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0481 0.1952 0.8514
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0313 0.1087 0.4688
Echinococcus multilocularis nervana 2 0.0391 0.149 0.1783
Entamoeba histolytica protein kinase, putative 0.0152 0.026 0.0688
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0258 0.0803 0.3429
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0334 0.1195 0.1172
Onchocerca volvulus 0.0115 0.0065 0.007
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0151 0.0254 0.1003
Entamoeba histolytica protein kinase, putative 0.0102 0.0002 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0284 0.0936 0.2481
Loa Loa (eye worm) SH2 domain-containing protein 0.0115 0.0065 0.0047
Echinococcus granulosus casein kinase I delta 0.0223 0.0624 0.0599
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0189 0.0449 0.0465
Echinococcus multilocularis casein kinase i 0.0223 0.0624 0.0728
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0244 0.0732 0.0859
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1288 0.6108 0.6629
Trichomonas vaginalis CMGC family protein kinase 0.0243 0.0728 0.191
Echinococcus multilocularis roundabout 2 0.012 0.0095 0.0084
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0438 0.1729 0.1708
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0783
Brugia malayi Protein kinase domain containing protein 0.0906 0.4141 0.4484
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0498 0.2039 0.2018
Echinococcus granulosus tyrosine protein kinase shark 0.0643 0.2786 0.2767
Echinococcus granulosus protein tyrosine kinase 0.1114 0.5209 0.5196
Brugia malayi Egg laying defective protein 4 0.0275 0.0891 0.0942
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.007 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Schistosoma mansoni shc transforming protein 0.0115 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0115 0.0065 0.007
Toxoplasma gondii casein kinase I 0.0223 0.0624 0.1633
Echinococcus granulosus tyrosine protein kinase Fyn 0.0467 0.1877 0.1856
Echinococcus multilocularis serine:threonine protein kinase 0.0234 0.068 0.0796
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0176 0.038 0.061
Brugia malayi Kinase associated domain 1 family protein 0.0204 0.0524 0.0542
Schistosoma mansoni tyrosine kinase 0.0714 0.3149 0.5394
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0179 0.0399 0.0454
Plasmodium falciparum NIMA related kinase 1 0.0278 0.0907 0.48
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0129 0.0138 0.0112
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0115 0.0065 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0027 0.0048
Brugia malayi protein kinase C II. 0.0519 0.2147 0.2311
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0206 0.0536 0.2775
Loa Loa (eye worm) hypothetical protein 0.0412 0.1596 0.1715
Brugia malayi SH2 domain containing protein 0.0823 0.3711 0.4015
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0498 0.2039 0.245
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0223 0.0624 0.2639
Schistosoma mansoni tyrosine kinase 0.0714 0.3149 0.5394
Loa Loa (eye worm) hypothetical protein 0.0189 0.0449 0.0465
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0411 0.1591 0.1906
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0411 0.1591 0.1705
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0669 0.1108
Echinococcus multilocularis dual specificity 0.0284 0.0936 0.1108
Brugia malayi Protein kinase domain containing protein 0.0262 0.0826 0.0871
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Plasmodium vivax protein kinase Crk2 0.0243 0.0728 0.3825
Onchocerca volvulus 0.0216 0.0587 0.1071
Brugia malayi Protein kinase domain containing protein 0.0389 0.1476 0.1579
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Brugia malayi Fibronectin type III domain containing protein 0.0207 0.0542 0.0561
Schistosoma mansoni tyrosine kinase 0.0643 0.2786 0.4766
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0485 0.0791
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Echinococcus granulosus expressed protein 0.0172 0.0361 0.0336
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0173 0.0367 0.1504
Schistosoma mansoni tyrosine kinase 0.0164 0.0321 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.1665 0.283
Brugia malayi tRNA modification GTPase TrmE family protein 0.0115 0.0065 0.0042
Loa Loa (eye worm) hypothetical protein 0.0207 0.0542 0.0567
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0645
Giardia lamblia Kinase, CMGC GSK 0.0263 0.083 0.355
Schistosoma mansoni protein kinase 0.0484 0.1968 0.3353
Echinococcus granulosus cyclin dependent kinase 9 0.0123 0.0109 0.0083
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0146 0.0228 0.0226
Leishmania major protein kinase, putative 0.0175 0.0377 0.1546
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.016 0.0299 0.0274
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0116 0.007 0.0053
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0115 0.0065 0.0039
Schistosoma mansoni protein kinase 0.1018 0.4715 0.8098
Brugia malayi serine/threonine kinase 12 0.0242 0.0723 0.0759
Loa Loa (eye worm) phosphatidylinositol 3 0.016 0.0299 0.0302
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0148 0.0235 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0341 0.1229 0.1316
Onchocerca volvulus 0.0377 0.1414 0.2652
Echinococcus granulosus mitogen activated protein kinase 14 0.0446 0.1773 0.1751
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Trichomonas vaginalis AGC family protein kinase 0.0278 0.0907 0.2385
Entamoeba histolytica hypothetical protein 0.0102 0.0002 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.1288 0.6108 0.6627
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0669 0.1108
Loa Loa (eye worm) hypothetical protein 0.0351 0.1283 0.1375
Loa Loa (eye worm) hypothetical protein 0.0207 0.0542 0.0567
Brugia malayi RhoGAP domain containing protein 0.0206 0.0533 0.0552
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0115 0.0065 0.0047
Leishmania major protein kinase A catalytic subunit isoform 1 0.0232 0.0669 0.2838
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0141 0.0203 0.0215
Onchocerca volvulus 0.0115 0.0065 0.007
Echinococcus multilocularis signal transduction protein lnk realted 0.0115 0.0065 0.0047
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0244 0.0732 0.1927
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0411 0.1591 0.171
Onchocerca volvulus 0.0115 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.0215 0.0584 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0426 0.0688
Plasmodium vivax serine/threonine kinase-1, putative 0.0313 0.1087 0.5783
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Echinococcus granulosus signal transduction protein lnk realted 0.0115 0.0065 0.0039
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0179 0.0399 0.0374
Echinococcus multilocularis serine:threonine protein kinase 0.0234 0.068 0.0796
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0184 0.0421 0.0396
Echinococcus granulosus TGF-beta receptor type-1 0.0141 0.0203 0.0177
Echinococcus multilocularis tensin 0.0115 0.0065 0.0047
Trypanosoma cruzi casein kinase, putative 0.0223 0.0624 0.2639
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0148 0.0235 0.0209
Brugia malayi Protein kinase domain containing protein 0.0199 0.0498 0.0514
Entamoeba histolytica protein kinase, putative 0.0423 0.1653 0.4382
Trichomonas vaginalis AGC family protein kinase 0.0232 0.0669 0.1752
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0243 0.0728 0.3101
Echinococcus granulosus dual specificity 0.0423 0.1653 0.1631
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0189 0.0449 0.0728
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0263 0.083 0.355
Brugia malayi Protein kinase domain containing protein 0.0432 0.1701 0.1824
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0823 0.3711 0.4486
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0131 0.015 0.014
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0711 0.3135 0.3391
Echinococcus granulosus epidermal growth factor receptor 0.0815 0.3672 0.3655
Schistosoma mansoni vav2 0.0223 0.0625 0.1033
Brugia malayi Protein kinase domain containing protein 0.0903 0.4124 0.4464
Toxoplasma gondii histone kinase SNF1, putative 0.0185 0.0426 0.109
Echinococcus granulosus mitogen activated protein kinase 11 0.0446 0.1773 0.1751
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0151 0.0253 0.0227
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.005 0.0133
Onchocerca volvulus 0.0223 0.0624 0.1141
Brugia malayi Protein kinase domain containing protein 0.044 0.1739 0.1866
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0243 0.0728 0.3101
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0377 0.1418 0.1695
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0206 0.0533 0.0874
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0367 0.0951
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0438 0.1729 0.2073
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0377 0.1418 0.1517
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0817 0.3681 0.3985
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0423 0.1653 0.7192
Giardia lamblia Kinase, STE STE20 0.0178 0.0391 0.1608
Echinococcus granulosus roundabout 2 0.0296 0.1001 0.0977
Echinococcus multilocularis cyclin dependent kinase 19 0.0199 0.0498 0.0575
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0115 0.0065 0.0047
Trichomonas vaginalis CMGC family protein kinase 0.0243 0.0728 0.191
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.083 0.22
Onchocerca volvulus 0.0968 0.4458 0.8477
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1206 0.5683 0.6166
Echinococcus granulosus serine:threonine protein kinase N2 0.0685 0.3 0.2982
Echinococcus multilocularis calcium dependent protein kinase 0.0172 0.0362 0.0409
Brugia malayi Sex muscle abnormal protein 5 0.0189 0.0449 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0361 0.0576
Echinococcus multilocularis mitogen activated protein kinase 14 0.0446 0.1773 0.2126
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0223 0.0624 0.0657
Echinococcus granulosus dual specificity 0.0284 0.0936 0.0912
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0467 0.1877 0.2253
Echinococcus granulosus Protein kinase C brain isozyme 0.0598 0.2555 0.2536
Trichomonas vaginalis CK1 family protein kinase 0.0223 0.0624 0.1633
Schistosoma mansoni kinase 0.0583 0.2478 0.4234
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0367 0.0951
Brugia malayi Protein kinase domain containing protein 0.0466 0.1876 0.2015
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0713 0.3147 0.38
Echinococcus granulosus c-Jun N-terminal kinases 0.0534 0.2226 0.2206
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Loa Loa (eye worm) TK protein kinase 0.0548 0.2294 0.2475
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0446 0.1773 0.7721
Echinococcus multilocularis roundabout 2 0.0296 0.1001 0.1186
Entamoeba histolytica hypothetical protein 0.0102 0.0002 0.0006
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.045 0.1793 0.2151
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0669 0.1108
Onchocerca volvulus 0.0185 0.0429 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Echinococcus granulosus casein kinase I alpha 0.0223 0.0624 0.0599
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0467 0.1877 0.2253
Brugia malayi Protein kinase domain 0.0178 0.0391 0.0397
Schistosoma mansoni tensin 0.0115 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0176 0.038 0.0391
Brugia malayi Protein kinase domain containing protein 0.189 0.9204 1
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.0723 0.1915
Echinococcus multilocularis tyrosine protein kinase Blk 0.0392 0.1493 0.1786
Giardia lamblia Kinase, STE STE20 0.0175 0.0377 0.1546
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0197 0.0491 0.0802
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0175 0.0377 0.0999
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0467 0.1877 0.2253
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0995 0.4595 0.4581
Loa Loa (eye worm) hypothetical protein 0.012 0.0095 0.008
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0723 0.1895
Entamoeba histolytica casein kinase, putative 0.0223 0.0624 0.1654
Echinococcus granulosus protein kinase 0.025 0.0763 0.0739
Brugia malayi serine/threonine-protein kinase plk-2 0.0546 0.2288 0.2464
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0115 0.0068 0.0045
Echinococcus granulosus suppressor of cytokine signaling 7 0.0115 0.0065 0.0039
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0645
Giardia lamblia Kinase, AGC PKA 0.0463 0.186 0.8107
Echinococcus multilocularis protein KINase family member (kin 25) 0.0163 0.0316 0.0353
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0185 0.0426 0.1762
Leishmania major protein kinase, putative 0.0313 0.1087 0.4688
Echinococcus multilocularis serine:threonine protein kinase 3 0.0519 0.215 0.2585
Echinococcus multilocularis CDC7 cell division cycle 7 0.0185 0.0429 0.0491
Brugia malayi protein kinase C3,putative 0.0329 0.1167 0.1242
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0021 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0228 0.0347
Plasmodium falciparum calcium-dependent protein kinase 4 0.0244 0.0732 0.3842
Echinococcus multilocularis serine:threonine protein kinase 38 0.0425 0.1665 0.1996
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0446 0.1773 0.7721
Echinococcus granulosus Immunoglobulin 0.0176 0.038 0.0355
Echinococcus multilocularis activin receptor type 0.0528 0.2195 0.2641
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0129 0.014 0.0139
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0384 0.0994
Plasmodium falciparum protein kinase 5 0.0243 0.0728 0.3825
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0275 0.0891 0.1053
Onchocerca volvulus 0.0216 0.0587 0.1071
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0938 0.4303 0.5206
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0244 0.0732 0.188
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0463 0.186 0.2233
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus granulosus growth factor receptor bound protein 2 0.0195 0.0477 0.0452
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0185 0.0426 0.0487
Echinococcus granulosus protein kinase shaggy 0.0263 0.083 0.0806
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.083 0.218
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0173 0.0367 0.1504
Onchocerca volvulus 0.0656 0.2853 0.5406
Echinococcus granulosus NDR protein kinase 0.0425 0.1665 0.1643
Brugia malayi SH2 domain containing protein 0.0115 0.0065 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0027 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Trypanosoma cruzi cdc2-related kinase 1 0.0243 0.0728 0.3101
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0113 0.0055 0.0121
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0645
Loa Loa (eye worm) hypothetical protein 0.0286 0.0945 0.1007
Echinococcus granulosus epidermal growth factor receptor 0.1231 0.5815 0.5804
Brugia malayi Stress-activated protein kinase jnk-1 0.0534 0.2226 0.2397
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0242 0.0723 0.0848
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0367 0.0951
Echinococcus granulosus nervana 2 0.0391 0.149 0.1468
Schistosoma mansoni serine/threonine protein kinase 0.0457 0.1829 0.3112
Trichomonas vaginalis AGC family protein kinase 0.0466 0.1876 0.4959
Echinococcus granulosus tensin 0.0115 0.0065 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0107 0.0026 0.0006
Echinococcus granulosus tyrosine protein kinase Blk 0.0392 0.1493 0.1471
Onchocerca volvulus 0.0197 0.0491 0.0887
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0232 0.0669 0.0783
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0995 0.4595 0.5563
Leishmania major protein kinase A catalytic subunit 0.0232 0.0669 0.2838
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0243 0.0728 0.1919
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0284 0.0936 0.402
Loa Loa (eye worm) hypothetical protein 0.0234 0.068 0.0718
Trichomonas vaginalis STE family protein kinase 0.0278 0.0907 0.2385
Entamoeba histolytica cell division protein kinase 2, putative 0.0243 0.0728 0.1931
Echinococcus granulosus hypothetical protein 0.0241 0.0717 0.0693
Entamoeba histolytica protein kinase, putative 0.0425 0.1665 0.4414
Loa Loa (eye worm) hypothetical protein 0.0376 0.141 0.1512
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0794 0.3564 0.3858
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0806 0.2118
Brugia malayi p70 ribosomal S6 kinase beta 0.0817 0.3681 0.3982
Schistosoma mansoni tensin-related 0.0115 0.0065 0.0064
Brugia malayi cytokine inducible SH2-containing protein 5 0.0115 0.0065 0.0042
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0129 0.014 0.0129
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0216 0.0584 0.0608
Brugia malayi Variant SH3 domain containing protein 0.0206 0.0533 0.0552
Schistosoma mansoni tensin 0.0115 0.0065 0.0064
Giardia lamblia Kinase, CMGC CDK 0.0243 0.0728 0.3101
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.1195 0.2017
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0711 0.3135 0.3117
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0263 0.083 0.0806
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0206 0.0533 0.0508
Echinococcus multilocularis tyrosine protein kinase HCK 0.0277 0.0903 0.1068
Echinococcus multilocularis Glutaredoxin protein 5 0.0391 0.149 0.1783
Loa Loa (eye worm) hypothetical protein 0.0412 0.1596 0.1715
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.083 0.22
Loa Loa (eye worm) hypothetical protein 0.0262 0.0826 0.0876
Echinococcus granulosus casein kinase I alpha 0.0223 0.0624 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0723 0.1201
Loa Loa (eye worm) TK protein kinase 0.0392 0.1493 0.1603
Leishmania major protein kinase, putative 0.0242 0.0723 0.3075
Echinococcus granulosus casein kinase ii subunit alpha 0.0206 0.0536 0.0511
Echinococcus multilocularis Immunoglobulin 0.0176 0.038 0.0431
Plasmodium falciparum calcium-dependent protein kinase 2 0.0244 0.0732 0.3842
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0263 0.083 0.1387
Echinococcus granulosus serine threonine protein kinase nrc 0.0463 0.186 0.1839
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0519 0.2147 0.2315
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0185 0.0426 0.1762
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0377 0.1418 0.1396
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Plasmodium vivax casein kinase 1, putative 0.0223 0.0624 0.3255
Trypanosoma brucei cdc2-related kinase 1 0.0243 0.0728 0.1872
Onchocerca volvulus Tyrosine kinase homolog 0.1122 0.5254 1
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0728 0.1211
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0723 0.1895
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0344 0.0889
Schistosoma mansoni serine/threonine-protein kinase 0.0481 0.1952 0.3325
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0232 0.0669 0.2838
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0242 0.0723 0.0698
Giardia lamblia Kinase, CAMK CAMKL 0.0192 0.0465 0.1936
Echinococcus multilocularis death associated protein kinase 1 0.1702 0.824 1
Schistosoma mansoni adapter molecule crk 0.0189 0.0449 0.0728
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0189 0.0449 0.0465
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Loa Loa (eye worm) hypothetical protein 0.0216 0.0587 0.0617
Entamoeba histolytica protein kinase domain containing protein 0.0206 0.0536 0.1421
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0197 0.0491 0.0802
Schistosoma mansoni titin 0.0153 0.0261 0.0404
Echinococcus multilocularis 0.0115 0.0065 0.0047
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0115 0.0068 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.1653 0.2809
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.3 0.5136
Brugia malayi Doublecortin family protein 0.0308 0.1058 0.1124
Loa Loa (eye worm) hypothetical protein 0.0197 0.0491 0.0512
Loa Loa (eye worm) hypothetical protein 0.0161 0.0303 0.0307
Loa Loa (eye worm) hypothetical protein 0.0197 0.0491 0.0512
Loa Loa (eye worm) hypothetical protein 0.0185 0.0426 0.0441
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0154 0.0266 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0894 0.1497
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0232 0.0669 0.1713
Brugia malayi Fes/CIP4 homology domain containing protein 0.0226 0.064 0.0669
Brugia malayi Protein kinase domain containing protein 0.0234 0.068 0.0712
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0463 0.186 1
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0135 0.017 0.0162
Trypanosoma cruzi polo-like protein kinase, putative 0.0546 0.2288 1
Trypanosoma cruzi Protein kinase B 0.0481 0.1952 0.8514
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0263 0.083 0.0881
Trypanosoma cruzi casein kinase, putative 0.0223 0.0624 0.2639
Loa Loa (eye worm) hypothetical protein 0.026 0.0814 0.0864
Giardia lamblia Kinase, STE STE20 0.0216 0.0584 0.2464
Entamoeba histolytica protein kinase, putative 0.0242 0.0723 0.1915
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0242 0.0723 0.1915
Giardia lamblia Kinase, CMGC SRPK 0.0172 0.0361 0.1475
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0534 0.2226 0.2678
Loa Loa (eye worm) hypothetical protein 0.0394 0.1506 0.1617
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0713 0.3147 0.3405
Loa Loa (eye worm) hypothetical protein 0.0837 0.3786 0.41
Entamoeba histolytica protein kinase, putative 0.0244 0.0732 0.1939
Echinococcus granulosus activated cdc42 kinase 1 0.0262 0.0826 0.0801
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0498 0.2039 0.245
Giardia lamblia Kinase, CMGC CK2 0.0206 0.0536 0.225
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Entamoeba histolytica protein kinase, putative 0.0263 0.083 0.22
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Brugia malayi Protein kinase domain containing protein 0.06 0.2562 0.2763
Echinococcus granulosus ephrin type A receptor 4 A 0.023 0.0657 0.0632
Brugia malayi SH2 domain containing protein 0.0216 0.0587 0.0611
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0115 0.0065 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Schistosoma mansoni nck2/grb4 0.0189 0.0449 0.0728
Plasmodium falciparum glycogen synthase kinase 3 0.0263 0.083 0.438
Brugia malayi Immunoglobulin I-set domain containing protein 0.0548 0.2294 0.2471
Echinococcus multilocularis dual specificity mitogen activated protein 0.0216 0.0584 0.068
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0131 0.0147 0.0366
Echinococcus multilocularis expressed conserved protein 0.0275 0.0891 0.1053
Onchocerca volvulus 0.0584 0.2483 0.4698
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.2288 0.6055
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0534 0.2226 0.2401
Loa Loa (eye worm) hypothetical protein 0.0244 0.0732 0.0774
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0172 0.0361 0.037
Echinococcus granulosus CDC7 cell division cycle 7 0.0185 0.0429 0.0404
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0313 0.1087 0.2829
Loa Loa (eye worm) hypothetical protein 0.0286 0.0945 0.1007
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0263 0.083 0.0979
Echinococcus multilocularis dual specificity 0.0284 0.0936 0.1108
Echinococcus granulosus mitogen activated protein kinase 3 0.0173 0.0367 0.0342
Echinococcus multilocularis mitogen activated protein kinase 11 0.0446 0.1773 0.2126
Entamoeba histolytica PH domain containing protein kinase, putative 0.0481 0.1952 0.5174
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0284 0.0936 0.0991
Trypanosoma brucei protein kinase, putative 0.0173 0.0367 0.0908
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0426 0.0688
Echinococcus multilocularis 0.0347 0.1263 0.1506
Brugia malayi Protein kinase domain containing protein 0.0391 0.149 0.1595
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0027 0.0048
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0196 0.0485 0.0506
Schistosoma mansoni tyrosine kinase 0.0714 0.3149 0.5394
Loa Loa (eye worm) TK protein kinase 0.0277 0.0903 0.0961
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0598 0.2555 0.3079
Brugia malayi Tyrosine-protein kinase abl-1 0.0449 0.1788 0.1919
Trypanosoma brucei aurora B kinase 0.0242 0.0723 0.1856
Loa Loa (eye worm) TK/INSR protein kinase 0.0906 0.4141 0.4487
Echinococcus granulosus rho-associated protein kinase 1 0.0656 0.2853 0.2834
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0391 0.149 0.1783
Schistosoma mansoni growth factor receptor-bound protein 0.0195 0.0477 0.0777
Mycobacterium ulcerans hypothetical protein 0.0203 0.0521 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0068 0.007
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0244 0.0732 0.0707
Brugia malayi hypothetical protein 0.0113 0.0056 0.0032
Echinococcus multilocularis aurora kinase A 0.0242 0.0723 0.0848
Brugia malayi hypothetical protein 0.0197 0.0491 0.0507
Schistosoma mansoni suppressor of cytokine signaling 0.0115 0.0065 0.0064
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0546 0.2288 0.2469
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0184 0.0421 0.0436
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Schistosoma mansoni protein kinase 0.025 0.0763 0.1271
Entamoeba histolytica protein kinase, putative 0.0247 0.0745 0.1974
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0151 0.0253 0.0276
Echinococcus granulosus tyrosine protein kinase HCK 0.0277 0.0903 0.0879
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0216 0.0584 0.1487
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0176 0.038 0.061
Brugia malayi P38 map kinase family protein 2 0.0446 0.1773 0.1903
Echinococcus multilocularis mitogen activated protein kinase 11 0.0446 0.1773 0.2126
Schistosoma mansoni ste20-related kinase 0.0416 0.1617 0.2747
Trypanosoma brucei casein kinase I, isoform 2 0.0223 0.0624 0.1593
Schistosoma mansoni nephrin 0.012 0.0095 0.0117
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0334 0.1195 0.1278
Echinococcus granulosus cGMP dependent protein kinase 1 0.0275 0.0891 0.0867
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0361 0.1475
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0148 0.0235 0.0254
Giardia lamblia Kinase, CDC7 0.0185 0.0429 0.1778
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Echinococcus multilocularis mitogen activated protein kinase 0.0173 0.0367 0.0415
Brugia malayi Protein kinase domain containing protein 0.0216 0.0587 0.0611
Echinococcus multilocularis SH2 domain containing protein 7 0.0115 0.0065 0.0047
Echinococcus multilocularis hypothetical protein 0.0204 0.0524 0.0606
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0176 0.038 0.0431
Giardia lamblia Kinase, AGC PKA 0.0232 0.0669 0.2838
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0438 0.1729 0.2073
Echinococcus granulosus tyrosine protein kinase Src64B 0.0467 0.1877 0.1856
Schistosoma mansoni neuroglian 0.012 0.0095 0.0117
Brugia malayi Variant SH3 domain containing protein 0.0135 0.017 0.0156
Onchocerca volvulus 0.0151 0.0254 0.0433
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0344 0.0889
Trichomonas vaginalis STE family protein kinase 0.0216 0.0584 0.1528
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0367 0.0587
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0723 0.1895
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0713 0.3147 0.3129
Plasmodium vivax protein kinase, putative 0.0132 0.0153 0.0685
Brugia malayi serine/threonine-protein kinase PAK 7 0.047 0.1895 0.2036
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0172 0.0361 0.0913
Loa Loa (eye worm) hypothetical protein 0.0132 0.0157 0.0148
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0163 0.0316 0.0291
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0275 0.0891 0.1053
Entamoeba histolytica hypothetical protein 0.0423 0.1653 0.4382
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0367 0.0951
Entamoeba histolytica serine/threonine protein kinase, putative 0.0185 0.0426 0.1128
Onchocerca volvulus 0.0971 0.4476 0.8511
Loa Loa (eye worm) hypothetical protein 0.0503 0.2064 0.2225
Echinococcus multilocularis ephrin type A receptor 4 A 0.023 0.0657 0.0768
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0173 0.0367 0.1504
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0244 0.0732 0.3842
Entamoeba histolytica protein kinase, putative 0.0135 0.0168 0.0444
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0169 0.0344 0.0387
Brugia malayi C1-like domain containing protein 0.0448 0.1784 0.1915
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0711 0.3135 0.3785
Entamoeba histolytica protein kinase 2, putative 0.0463 0.186 0.493
Echinococcus multilocularis raf serine:threonine protein kinase 0.0193 0.0466 0.0536
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0467 0.1877 0.2253
Brugia malayi cyclin-dependent kinase 9 0.0116 0.007 0.0047
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0206 0.0533 0.0874
Loa Loa (eye worm) hypothetical protein 0.0351 0.1283 0.1375
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0172 0.0361 0.1475
Onchocerca volvulus 0.015 0.0249 0.0424
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0173 0.0367 0.093
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0153 0.0261 0.0261
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.0391 0.0366
Echinococcus granulosus SH2 domain containing adapter protein F 0.0115 0.0065 0.0039
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0296 0.0996 0.0973
Loa Loa (eye worm) hypothetical protein 0.0479 0.1943 0.2094
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0216 0.0587 0.1557
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0115 0.0065 0.0042
Echinococcus granulosus hypothetical protein 0.0115 0.0065 0.0039
Schistosoma mansoni tyrosine kinase 0.0498 0.2039 0.3475
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0425 0.1665 0.1643
Echinococcus granulosus expressed conserved protein 0.0115 0.0065 0.0039
Onchocerca volvulus 0.0263 0.083 0.1535
Entamoeba histolytica protein kinase, putative 0.0169 0.0344 0.0912
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0392 0.1493 0.1786
Entamoeba histolytica protein kinase domain containing protein 0.0116 0.007 0.0184
Schistosoma mansoni protein kinase 0.0173 0.0367 0.0587
Schistosoma mansoni protein kinase 0.0135 0.0168 0.0242
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0102 0.0002 0.0006
Brugia malayi Temporarily assigned gene name protein 59 0.0258 0.0803 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.2288 0.3906
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.0936 0.157
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.1087 0.1831
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.083 0.218
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0185 0.0426 0.1762
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0192 0.0465 0.0483
Echinococcus granulosus Vam6:Vps39 protein 0.0197 0.0491 0.0467
Schistosoma mansoni protein kinase 0.0141 0.0203 0.0303
Echinococcus multilocularis serine threonine protein kinase 0.0507 0.2087 0.2508
Leishmania major casein kinase, putative 0.0223 0.0624 0.2639
Schistosoma mansoni GTPase activating protein 0.0115 0.0065 0.0064
Schistosoma mansoni hypothetical protein 0.0197 0.0491 0.0802
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0794 0.3564 0.3547
Echinococcus granulosus aurora kinase A 0.0242 0.0723 0.0698
Loa Loa (eye worm) hypothetical protein 0.0721 0.3188 0.3449
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0426 0.0688
Echinococcus multilocularis dual specificity protein kinase clk2 0.0313 0.1087 0.1292
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0774 0.3458 0.3743
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Loa Loa (eye worm) hypothetical protein 0.0412 0.1596 0.1715
Schistosoma mansoni tyrosine kinase 0.0467 0.1877 0.3195
Schistosoma mansoni hypothetical protein 0.0115 0.0065 0.0064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0184 0.0421 0.0436
Echinococcus granulosus dual specificity 0.0284 0.0936 0.0912
Loa Loa (eye worm) hypothetical protein 0.0176 0.038 0.0391
Loa Loa (eye worm) hypothetical protein 0.0113 0.0056 0.0038
Loa Loa (eye worm) CAMK protein kinase 0.0153 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0241 0.0717 0.0758
Brugia malayi Tensin 0.0115 0.0065 0.0042
Schistosoma mansoni tyrosine kinase 0.0815 0.3672 0.6297
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0232 0.0669 0.2838
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0407 0.1572 0.1689
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0423 0.1653 0.7192
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0055 0.0121
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0457 0.1829 0.2195
Echinococcus granulosus casein kinase I alpha 0.0223 0.0624 0.0599
Entamoeba histolytica PH domain containing protein kinase, putative 0.025 0.0761 0.2017
Echinococcus granulosus tyrosine protein kinase 0.0581 0.2466 0.2446
Trypanosoma brucei Casein kinase II 0.0206 0.0536 0.1358
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0115 0.0068 0.0051
Brugia malayi ribosomal protein S6 kinase alpha 3 0.024 0.0711 0.0746
Echinococcus granulosus suppressor of cytokine signaling 6 0.0115 0.0065 0.0039
Brugia malayi Cam kinase protein 1 0.0244 0.0732 0.0768
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.012 0.0095 0.0069
Loa Loa (eye worm) hypothetical protein 0.0207 0.0542 0.0567
Brugia malayi Pleckstrin Homology Domain 0.0109 0.0035 0.001
Brugia malayi Protein kinase domain containing protein 0.0131 0.015 0.0135
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0232 0.0669 0.3501
Entamoeba histolytica hypothetical protein 0.076 0.3388 0.898
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0938 0.4303 0.4288
Entamoeba histolytica protein kinase, putative 0.0172 0.0361 0.0957
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0425 0.1665 0.1643
Plasmodium falciparum calcium-dependent protein kinase 5 0.0244 0.0732 0.3842
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0115 0.0065 0.0047
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0278 0.0907 0.48
Loa Loa (eye worm) TK/EGFR protein kinase 0.1231 0.5815 0.631
Onchocerca volvulus 0.0286 0.0945 0.1756
Schistosoma mansoni tyrosine kinase 0.0755 0.3363 0.5762
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Brugia malayi Protein kinase domain containing protein 0.0835 0.3773 0.4082
Loa Loa (eye worm) hypothetical protein 0.0115 0.0065 0.0047
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0824 0.3718 0.4495
Echinococcus granulosus serine:threonine protein kinase 3 0.0519 0.215 0.2129
Brugia malayi Protein kinase domain containing protein 0.0711 0.3135 0.3388
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0467 0.1877 0.1856
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0429 0.1116
Loa Loa (eye worm) hypothetical protein 0.0177 0.0385 0.0396
Loa Loa (eye worm) SH2 domain-containing protein 0.0115 0.0065 0.0047
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0546 0.2288 0.2754
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus multilocularis 0.025 0.0763 0.0897
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0823 0.3711 0.3695
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0467 0.1877 0.1856
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0184 0.0421 0.043
Loa Loa (eye worm) TK protein kinase 0.0581 0.2466 0.2663
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0261 0.0404
Onchocerca volvulus 0.0115 0.0065 0.007
Echinococcus multilocularis casein kinase I gamma 0.0432 0.1701 0.2039
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0131 0.0147 0.0366
Echinococcus granulosus cyclin dependent kinase 1 0.0243 0.0728 0.0704
Loa Loa (eye worm) AGC/AKT protein kinase 0.0835 0.3773 0.4086
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0244 0.0732 0.0774
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0463 0.186 0.1839
Echinococcus multilocularis tyrosine protein kinase Abl 0.0449 0.1788 0.2145
Plasmodium falciparum calcium-dependent protein kinase 3 0.0244 0.0732 0.3842
Echinococcus granulosus tyrosine protein kinase Srms 0.1031 0.4785 0.4771
Echinococcus granulosus N chimaerin 0.0206 0.0533 0.0508
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0173 0.0367 0.1504
Echinococcus multilocularis protein kinase c epsilon type 0.0519 0.2147 0.2582
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0232 0.0669 0.1713
Loa Loa (eye worm) hypothetical protein 0.0128 0.0134 0.0123
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0723 0.0764
Plasmodium vivax serine/threonine protein kinase, putative 0.0172 0.0361 0.1819
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0243 0.0728 0.077
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0243 0.0728 0.0704
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0391 0.149 0.1468
Brugia malayi phosphoinositide-dependent protein kinase I 0.0169 0.0344 0.0346
Echinococcus multilocularis Immunoglobulin 0.0176 0.038 0.0431
Echinococcus multilocularis titin 0.0153 0.0261 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0894 0.1497
Echinococcus granulosus calcium activated potassium channel 0.0276 0.0894 0.087
Brugia malayi Hr1 repeat family protein 0.0685 0.3 0.3241
Loa Loa (eye worm) hypothetical protein 0.0163 0.0316 0.0322
Echinococcus multilocularis SH2 motif 0.0115 0.0065 0.0047
Entamoeba histolytica protein kinase domain containing protein 0.0423 0.1653 0.4382
Loa Loa (eye worm) AGC/PKA protein kinase 0.0232 0.0669 0.0706
Echinococcus granulosus tyrosine protein kinase Src42A 0.0467 0.1877 0.1856
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0173 0.0367 0.0908
Schistosoma mansoni protein kinase 0.0484 0.1968 0.3353
Trichomonas vaginalis CMGC family protein kinase 0.0284 0.0936 0.2462
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0774 0.3458 0.3739
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Onchocerca volvulus 0.0115 0.0065 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0728 0.1211
Toxoplasma gondii AGC kinase 0.0232 0.0669 0.1756
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0169 0.0344 0.0352
Echinococcus granulosus activin receptor type 0.0528 0.2195 0.2175
Schistosoma mansoni signal transduction protein lnk-related 0.0115 0.0065 0.0064
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0206 0.0533 0.0617
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0186 0.0434 0.1151
Schistosoma mansoni tyrosine kinase 0.0191 0.0456 0.0741
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0175 0.0377 0.0933
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus granulosus tyrosine protein kinase Lyn 0.0538 0.2247 0.2226
Entamoeba histolytica protein kinase, putative 0.0172 0.0361 0.0957
Brugia malayi cyclin-dependent kinase 7 homolog 0.0154 0.0268 0.0263
Loa Loa (eye worm) hypothetical protein 0.0265 0.0839 0.0891
Brugia malayi Protein kinase domain containing protein 0.0216 0.0587 0.0611
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1018 0.4715 0.5708
Schistosoma mansoni protein kinase 0.0178 0.0391 0.0628
Brugia malayi ephrin receptor 1 precursor 0.0162 0.0308 0.0307
Loa Loa (eye worm) hypothetical protein 0.0287 0.0953 0.1015
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0457 0.1829 0.1807
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Brugia malayi Protein kinase domain containing protein 0.0713 0.3147 0.3401
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0199 0.0498 0.052
Brugia malayi Protein kinase domain containing protein 0.0968 0.4458 0.4829
Schistosoma mansoni tyrosine kinase 0.0815 0.3672 0.6297
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0426 0.1106
Schistosoma mansoni hypothetical protein 0.0204 0.0524 0.0858
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Echinococcus multilocularis c src tyrosine kinase 0.0291 0.0971 0.1151
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0232 0.0669 0.1713
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0192 0.0465 0.2389
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0275 0.0891 0.2364
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Giardia lamblia Kinase, AGC AKT 0.024 0.0711 0.3022
Leishmania major protein kinase A catalytic subunit isoform 2 0.0232 0.0669 0.2838
Brugia malayi Variant SH3 domain containing protein 0.0189 0.0449 0.046
Trichomonas vaginalis AGC family protein kinase 0.0835 0.3773 1
Brugia malayi probable protein kinase 0.0448 0.178 0.191
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0173 0.0367 0.0908
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0115 0.0065 0.0039
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0269 0.0861 0.1017
Giardia lamblia Kinase, CMGC GSK 0.0263 0.083 0.355
Echinococcus granulosus serine:threonine protein kinase 0.0234 0.068 0.0656
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0168 0.0339 0.0854
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0446 0.1773 0.466
Echinococcus multilocularis tyrosine protein kinase 0.0581 0.2466 0.2971
Entamoeba histolytica protein kinase, putative 0.0186 0.0434 0.1151
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0411 0.1591 0.1569
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0115 0.0068 0.0179
Schistosoma mansoni kinase 0.0116 0.007 0.0073
Entamoeba histolytica protein kinase domain containing protein 0.0411 0.1591 0.4218
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0536 0.1399
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1206 0.5683 0.6166
Loa Loa (eye worm) TK/ALK protein kinase 0.0599 0.2561 0.2766
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0467 0.1877 0.2253
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0173 0.0367 0.1504
Schistosoma mansoni protein kinase 0.1018 0.4715 0.8098
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0894 0.1497
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0206 0.0533 0.0558
Giardia lamblia Kinase, NEK 0.0278 0.0907 0.3891
Schistosoma mansoni serine/threonine kinase 0.0447 0.1779 0.3026
Onchocerca volvulus Serine\/threonine kinase homolog 0.0546 0.2288 0.4325
Echinococcus multilocularis N chimaerin 0.0206 0.0533 0.0617
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0732 0.1217
Echinococcus granulosus cyclin dependent kinase 0.0243 0.0728 0.0704
Loa Loa (eye worm) hypothetical protein 0.0923 0.4226 0.4579
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.044 0.1739 0.1871
Brugia malayi intracellular kinase 0.0263 0.083 0.0876
Echinococcus granulosus cGMP dependent protein kinase 0.0275 0.0891 0.0867
Echinococcus granulosus serine:threonine protein kinase N2 0.0259 0.081 0.0786
Echinococcus granulosus calcium dependent protein kinase 0.0172 0.0362 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0147 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.1087 0.1831
Echinococcus multilocularis cyclin dependent kinase 7 0.0146 0.0228 0.0246
Schistosoma mansoni tyrosine kinase 0.0516 0.2133 0.3638
Schistosoma mansoni cell adhesion molecule 0.012 0.0095 0.0117
Loa Loa (eye worm) hypothetical protein 0.1206 0.5683 0.6166
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.078 0.3493 0.3781
Plasmodium falciparum casein kinase 2, alpha subunit 0.0206 0.0536 0.2775
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0115 0.0065 0.0047
Brugia malayi hypothetical protein 0.0207 0.0542 0.0561
Echinococcus granulosus tyrosine protein kinase ABL1 0.0631 0.2723 0.2704
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0548
Entamoeba histolytica hypothetical protein 0.0102 0.0002 0.0006
Entamoeba histolytica protein kinase, putative 0.0152 0.026 0.0688
Giardia lamblia Kinase, CMGC MAPK 0.0173 0.0367 0.1504
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0173 0.0367 0.0377
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0095 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0498 0.0814
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0176 0.0384 0.0395
Echinococcus granulosus dual specificity mitogen activated protein 0.0216 0.0584 0.056
Echinococcus granulosus neuroglian 0.0225 0.0636 0.0611
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0313 0.1087 0.2901
Entamoeba histolytica protein kinase, putative 0.0242 0.0723 0.1915
Loa Loa (eye worm) hypothetical protein 0.0113 0.0056 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0095 0.0075
Echinococcus granulosus SH2 motif 0.0115 0.0065 0.0039
Brugia malayi Protein kinase domain containing protein 0.0185 0.0429 0.0439
Loa Loa (eye worm) hypothetical protein 0.0721 0.3188 0.3449
Trypanosoma cruzi cdc2-related kinase 3 0.0243 0.0728 0.3101
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.0587 0.0617
Schistosoma mansoni tyrosine kinase 0.0467 0.1877 0.3195
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.0391 0.0444
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0284 0.0936 0.2426
Plasmodium falciparum protein serine/threonine kinase-1 0.0313 0.1087 0.5783
Echinococcus granulosus c src tyrosine kinase 0.0291 0.0971 0.0948
Brugia malayi Protein kinase domain containing protein 0.0216 0.0587 0.0611
Echinococcus granulosus twitchin 0.0297 0.1005 0.0982
Brugia malayi Protein kinase domain containing protein 0.0423 0.1653 0.1773
Schistosoma mansoni tyrosine kinase 0.0291 0.0971 0.1631
Brugia malayi Protein kinase domain containing protein 0.0129 0.014 0.0124
Brugia malayi casein kinase 1, delta 0.0223 0.0624 0.0651
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0185 0.0426 0.1762
Leishmania major protein kinase, putative 0.0244 0.0732 0.3115
Echinococcus multilocularis tyrosine protein kinase Srms 0.0392 0.1493 0.1786
Brugia malayi MAP kinase sur-1 0.0173 0.0367 0.0372
Schistosoma mansoni tyrosine kinase 0.0291 0.0971 0.1631
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0711 0.3135 0.5946
Schistosoma mansoni protein kinase 0.0448 0.178 0.3027
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0244 0.0732 0.0768
Echinococcus multilocularis mitogen activated protein kinase 3 0.0173 0.0367 0.0415
Entamoeba histolytica protein kinase, putative 0.0148 0.0235 0.0622
Plasmodium vivax calcium-dependent protein kinase, putative 0.0244 0.0732 0.3842
Echinococcus granulosus serine/threonine protein kinase 0.0481 0.1952 0.1931
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0377 0.1546
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0055 0.0121
Brugia malayi Variant SH3 domain containing protein 0.0189 0.0449 0.046
Echinococcus multilocularis serine:threonine protein kinase N2 0.0259 0.081 0.0954
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.016 0.0299 0.0332
Echinococcus multilocularis rac serine:threonine kinase 0.0481 0.1952 0.2345
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0815 0.3672 0.3655
Echinococcus granulosus dual specificity 0.0284 0.0936 0.0912
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0284 0.0936 0.2487
Loa Loa (eye worm) AGC/PKN protein kinase 0.0685 0.3 0.3244
Brugia malayi Protein kinase domain containing protein 0.0313 0.1087 0.1156
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0407 0.1572 0.1882
Trichomonas vaginalis CAMK family protein kinase 0.0554 0.2327 0.6159
Echinococcus multilocularis insulin receptor 0.0906 0.4141 0.501
Entamoeba histolytica PH domain containing protein kinase, putative 0.0481 0.1952 0.5174

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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