Detailed information for compound 990394

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 374.494 | Formula: C21H26O4S
  • H donors: 0 H acceptors: 2 LogP: 4.73 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCSC(c1cc(OC)c2c(c1OC)C(=O)C=CC2=O)CC=C(C)C
  • InChi: 1S/C21H26O4S/c1-6-11-26-18(10-7-13(2)3)14-12-17(24-4)19-15(22)8-9-16(23)20(19)21(14)25-5/h7-9,12,18H,6,10-11H2,1-5H3
  • InChiKey: KDHXLIQVAJAIPZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0136 0.0265
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0309 0.0622
Brugia malayi Steroid receptor seven-up type 2 0.0078 0.0405 0.0821
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.0082
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0582 0.4282
Brugia malayi Kelch motif family protein 0.0047 0.0208 0.0419
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0211 0.0417
Leishmania major cathepsin L-like protease 0.0017 0.0017 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Brugia malayi Furin-like cysteine rich region family protein 0.0298 0.1787 0.3637
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0046 0.0204 0.1605
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0322 0.065
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0149 0.0297
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0438 0.0432
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0065 0.0102
Brugia malayi hypothetical protein 0.0233 0.138 0.2807
Schistosoma mansoni nephrin 0.0026 0.0079 0.0154
Brugia malayi beta-tubulin, identical 0.0794 0.4909 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.0005
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0817 0.1658
Loa Loa (eye worm) BEN-1 protein 0.0794 0.4909 1
Onchocerca volvulus 0.0035 0.0136 0.0846
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.097 0.6742
Entamoeba histolytica tubulin family protein 0.0794 0.4909 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0794 0.4909 0.4906
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0269 0.0543
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0145 0.0289
Giardia lamblia Epsilon tubulin 0.023 0.1359 0.2746
Schistosoma mansoni tyrosine kinase 0.0162 0.0931 0.189
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0078 0.0405 0.0821
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Schistosoma mansoni organic anion transporter 0.0055 0.0259 0.0521
Echinococcus granulosus expressed conserved protein 0.0183 0.1063 0.2156
Leishmania major beta tubulin 0.0794 0.4909 1
Echinococcus multilocularis tubulin alpha 3 chain 0.0591 0.363 0.3626
Onchocerca volvulus 0.0028 0.0091 0.0526
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0309 0.0622
Brugia malayi Smad1 0.0016 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.0047 0.0208 0.0419
Plasmodium falciparum glutathione reductase 0.0047 0.0206 0.0392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0037 0.0145 0.0291
Echinococcus granulosus c src tyrosine kinase 0.0019 0.003 0.0048
Onchocerca volvulus Bile acid receptor homolog 0.0078 0.0405 0.275
Trypanosoma cruzi tubulin delta chain 0.0368 0.2229 0.4536
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0192 0.0378
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0014 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Brugia malayi Thioredoxin reductase 0.0047 0.0206 0.0415
Brugia malayi Fibronectin type III domain containing protein 0.0023 0.0061 0.0118
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0299
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0269 0.0535
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.017 0.0164
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0245 0.0494
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0049 0.022 0.0443
Echinococcus multilocularis smad 0.0016 0.0014 0.0008
Echinococcus multilocularis tubulin alpha chain 0.0591 0.363 0.3626
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0259 0.1713
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Loa Loa (eye worm) DR-78 0.0037 0.0145 0.0291
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0145 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Echinococcus multilocularis beta tubulin 0.0794 0.4909 0.4906
Loa Loa (eye worm) beta-lactamase 0.0035 0.0136 0.0273
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0065 0.0125
Echinococcus granulosus lamin dm0 0.0027 0.008 0.0151
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.0017
Leishmania major cathepsin L-like protease 0.0063 0.0309 0.0617
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.01 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0582 0.4282
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0215 0.0431
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0142 0.0277
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0136 0.0918
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0794 0.4909 0.4906
Loa Loa (eye worm) tubulin alpha 2 0.0387 0.235 0.4784
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.001
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0006 0.0006
Echinococcus granulosus Tubulin alpha 1 chain 0.0591 0.363 0.7392
Schistosoma mansoni tyrosine kinase 0.0156 0.0897 0.1821
Loa Loa (eye worm) tubulin beta-1 chain 0.0794 0.4909 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0037 0.0145 0.0283
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.003 0.0054
Trichomonas vaginalis tubulin alpha chain, putative 0.0445 0.271 0.5515
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0259 0.0515
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0269 0.0535
Toxoplasma gondii beta-tubulin, putative 0.0794 0.4909 1
Echinococcus granulosus tubulin alpha chain 0.0591 0.363 0.7392
Treponema pallidum cell division protein FtsZ 0.0203 0.1193 1
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0226 0.0433
Schistosoma mansoni integrin alpha-ps 0.0068 0.0338 0.0682
Schistosoma mansoni tubulin subunit beta 0.0203 0.1193 0.2426
Trichomonas vaginalis tubulin, putative 0.0241 0.143 0.2903
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0136 0.013
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0168 0.0338
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0149 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0078 0.0405 0.0821
Echinococcus granulosus integrin alpha 3 0.0116 0.064 0.1293
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.1523 0.3099
Plasmodium falciparum alpha tubulin 1 0.0591 0.363 0.7387
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0017 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis tubulin epsilon chain, putative 0.0794 0.4909 1
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0136 0.0918
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Schistosoma mansoni integrin alpha-ps 0.0035 0.0134 0.0267
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Leishmania major beta tubulin 0.0794 0.4909 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0204 0.0387
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0817 0.1659
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0206 0.042
Toxoplasma gondii alpha tubulin TUBA1 0.0591 0.363 0.7393
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0065 0.0119
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0078 0.0405 0.0819
Echinococcus multilocularis tubulin alpha chain 0.0591 0.363 0.3626
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0149 0.0299
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0065 0.0058
Leishmania major phosphopantetheinyl transferase-like protein 0.0046 0.0204 0.0403
Loa Loa (eye worm) steroid hormone receptor 0.0078 0.0405 0.0821
Brugia malayi hypothetical protein 0.022 0.1299 0.2642
Echinococcus granulosus cpg binding protein 0.003 0.0101 0.0193
Entamoeba histolytica hypothetical protein 0.0071 0.036 0.0734
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0136 0.0271
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0046 0.0204 0.1684
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0211 0.0205
Brugia malayi Tubulin beta chain 0.0241 0.143 0.2909
Leishmania major trypanothione reductase 0.0047 0.0206 0.0408
Loa Loa (eye worm) tubulin alpha-2 chain 0.0591 0.363 0.7394
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.0023
Echinococcus granulosus roundabout 2 0.0029 0.0098 0.0187
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Onchocerca volvulus 0.0055 0.0259 0.1713
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0149 0.0297
Schistosoma mansoni tubulin subunit gamma 0.0471 0.2878 0.5859
Leishmania major beta tubulin 0.0794 0.4909 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0273 0.0549
Toxoplasma gondii ABC1 family protein 0.0035 0.0136 0.0271
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0259 0.0253
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Echinococcus granulosus tumor protein p63 0.0333 0.2009 0.4085
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0309 0.0622
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Echinococcus multilocularis tyrosine protein kinase Abl 0.0096 0.0519 0.0513
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Echinococcus multilocularis tubulin beta 1 chain 0.0794 0.4909 0.4906
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0023
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0017 0.0029
Entamoeba histolytica hypothetical protein 0.0071 0.036 0.0734
Loa Loa (eye worm) TK protein kinase 0.0041 0.017 0.0341
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0149 0.0299
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0142 0.0277
Schistosoma mansoni thyroid hormone receptor 0.0202 0.1186 0.2411
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.0146
Plasmodium falciparum tubulin beta chain 0.0794 0.4909 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0078 0.0405 0.0814
Echinococcus granulosus tubulin alpha chain 0.0591 0.363 0.7392
Brugia malayi beta-lactamase family protein 0.0035 0.0136 0.0273
Mycobacterium ulcerans cell division protein FtsZ 0.0203 0.1193 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0023 0.0046
Echinococcus granulosus tubulin alpha 3 chain 0.0591 0.363 0.7392
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0269 0.2157
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0017 0.0021
Echinococcus granulosus neuropeptide s receptor 0.0464 0.2836 0.5771
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0211 0.0205
Leishmania major hypothetical protein, conserved 0.005 0.0226 0.0449
Brugia malayi Tyrosine-protein kinase abl-1 0.0126 0.0703 0.1428
Entamoeba histolytica tubulin alpha chain, putative 0.0591 0.363 0.7395
Echinococcus granulosus tyrosine kinase 0.0041 0.017 0.0334
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0062 0.0113
Echinococcus granulosus beta tubulin 0.0794 0.4909 1
Schistosoma mansoni hypothetical protein 0.0048 0.0212 0.0425
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Schistosoma mansoni hypothetical protein 0.0071 0.036 0.0728
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.008 0.0158
Loa Loa (eye worm) TK protein kinase 0.0106 0.0577 0.1171
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0149 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0142 0.0261
Echinococcus granulosus tyrosine protein kinase Blk 0.0041 0.017 0.0334
Onchocerca volvulus 0.0055 0.0259 0.1713
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0065 0.0119
Loa Loa (eye worm) TK/INSR protein kinase 0.0098 0.0528 0.1071
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0309 0.0622
Echinococcus granulosus follistatin 0.0038 0.0149 0.0291
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0136 0.1032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0062 0.0119
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0259 0.0521
Echinococcus granulosus tubulin subunit TubB 0.0591 0.363 0.7392
Trypanosoma brucei zeta tubulin, putative 0.0478 0.2924 0.5951
Schistosoma mansoni patched 1 0.0084 0.0438 0.0887
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0016
Leishmania major beta tubulin 0.0794 0.4909 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0142 0.0283
Echinococcus granulosus tm gpcr rhodopsin 0.0521 0.3193 0.6498
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0037 0.0145 0.0289
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.0204
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0179
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0269 0.1918
Leishmania major beta tubulin 0.0794 0.4909 1
Brugia malayi MH1 domain containing protein 0.0016 0.0014 0.0024
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0168 0.0162
Echinococcus multilocularis hypothetical protein 0.0591 0.363 0.3626
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0065 0.0125
Leishmania major cathepsin L-like protease 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0114 0.0631 0.128
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Leishmania major beta tubulin 0.0794 0.4909 1
Brugia malayi Tubulin beta-1 chain 0.0794 0.4909 1
Echinococcus granulosus insulin receptor 0.0098 0.0528 0.1063
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0211 0.0417
Echinococcus granulosus tubulin beta 1 chain 0.0794 0.4909 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.036 0.0722
Schistosoma mansoni cpg binding protein 0.003 0.0101 0.0199
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0014 0.0016
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0045 0.0078
Echinococcus multilocularis tubulin alpha chain 0.0591 0.363 0.3626
Loa Loa (eye worm) integrin alpha pat-2 0.0232 0.1375 0.2798
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Echinococcus granulosus fibroblast growth factor receptor 4 0.0103 0.0559 0.1126
Echinococcus granulosus bloom syndrome protein 0.0041 0.0168 0.033
Brugia malayi hypothetical protein 0.0071 0.036 0.0729
Echinococcus granulosus tubulin alpha chain 0.0591 0.363 0.7392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Schistosoma mansoni agrin 0.0038 0.0149 0.0297
Leishmania major gamma-tubulin 0.0471 0.2878 0.5857
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0136 0.013
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0241 0.143 0.2903
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0015 0.0017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0037 0.0145 0.0909
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0136 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0083 0.0436 0.0884
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0023 0.007
Loa Loa (eye worm) nuclear receptor NHR-67 0.0037 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.005 0.0226 0.0456
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0157 0.029
Trichomonas vaginalis tubulin gamma chain, putative 0.0471 0.2878 0.5857
Brugia malayi Nuclear hormone receptor-like 1 0.0078 0.0405 0.0821
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0017 0.0005
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.006 0.0385
Schistosoma mansoni tyrosine kinase 0.0047 0.0211 0.0423
Trypanosoma brucei tubulin delta chain 0.0368 0.2229 0.4532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0151 0.0295
Echinococcus granulosus geminin 0.0335 0.2021 0.4108
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.006 0.0343
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0023 0.0436
Echinococcus multilocularis thyroid hormone receptor alpha 0.0202 0.1186 0.1181
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0179
Onchocerca volvulus 0.0049 0.022 0.1436
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Brugia malayi Protein kinase domain containing protein 0.0098 0.0528 0.1071
Leishmania major beta tubulin 0.0794 0.4909 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0046 0.0204 0.0408
Schistosoma mansoni hypothetical protein 0.0102 0.0555 0.1124
Echinococcus granulosus defective proboscis extension response 0.0021 0.0043 0.0074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0078 0.0405 0.0821
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0848
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0103
Onchocerca volvulus 0.0055 0.0259 0.1713
Loa Loa (eye worm) hypothetical protein 0.0026 0.0077 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0192 0.0378
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0657 0.4845
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0224 0.0451
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0065 0.0119
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0017
Loa Loa (eye worm) TK/EGFR protein kinase 0.0298 0.1787 0.3637
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0041 0.0173 0.0167
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0198 0.0192
Trypanosoma cruzi tubulin delta chain 0.0368 0.2229 0.4536
Loa Loa (eye worm) tubulin beta chain 0.0794 0.4909 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0103 0.0559 0.0553
Brugia malayi nuclear receptor NHR-88 0.0037 0.0145 0.0291
Leishmania major beta tubulin 0.0794 0.4909 1
Trypanosoma brucei beta tubulin 0.0794 0.4909 1
Leishmania major hypothetical protein, conserved 0.0035 0.0136 0.0265
Brugia malayi nuclear receptor NHR-88 0.0078 0.0405 0.0821
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0078 0.0405 0.0399
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0173 0.0348
Brugia malayi CHE-14 protein 0.0084 0.0438 0.0888
Schistosoma mansoni alpha tubulin 0.0591 0.363 0.7393
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0142 0.0277
Loa Loa (eye worm) hypothetical protein 0.022 0.1299 0.2642
Echinococcus granulosus tubulin alpha chain 0.0591 0.363 0.7392
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0582 0.4282
Trichomonas vaginalis tubulin epsilon chain, putative 0.0591 0.363 0.7392
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0259 0.0521
Brugia malayi hypothetical protein 0.0041 0.0173 0.0348
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0149 0.0299
Echinococcus multilocularis tumor protein p63 0.0333 0.2009 0.2004
Echinococcus granulosus tyrosine protein kinase ABL1 0.0215 0.1269 0.2574
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1026 0.208
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.003
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0109 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0206 0.0415
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0109 0.0103
Trypanosoma brucei beta tubulin 0.0794 0.4909 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0136 0.1032
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0017 0.0034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0078 0.0405 0.0399
Schistosoma mansoni alpha tubulin 0.0591 0.363 0.7393
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0387 0.235 0.478
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0078 0.0405 0.0821
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0091 0.018
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0078 0.0405 0.0821
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0142 0.0136
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0037 0.0145 0.0289
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0149 0.0299
Brugia malayi tubulin alpha-2 chain 0.0591 0.363 0.7394
Loa Loa (eye worm) integrin beta-2 0.0309 0.1856 0.3777
Schistosoma mansoni tyrosine kinase 0.0019 0.003 0.0054
Echinococcus multilocularis neuroglian 0.0024 0.0061 0.0055
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0211 0.0205
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0192 0.0391
Leishmania major delta tubulin, putative 0.0368 0.2229 0.4532
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0101 0.0546 0.054
Giardia lamblia Gamma tubulin 0.0471 0.2878 0.585
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0322 0.0645
Brugia malayi conserved hypotetical protein 0.0037 0.0145 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0135 0.0262
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0204 0.0415
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0179 0.0357
Echinococcus granulosus ecdysone induced protein 78C 0.0078 0.0405 0.0814
Schistosoma mansoni tubulin subunit alpha 0.0591 0.363 0.7393
Onchocerca volvulus 0.0027 0.008 0.0449
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0216
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0438 0.0881
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0078 0.0405 0.0821
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.003 0.0024
Echinococcus granulosus tubulin alpha chain 0.0591 0.363 0.7392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0029
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0203 0.1193 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0096 0.019
Schistosoma mansoni tyrosine kinase 0.0156 0.0897 0.1821
Echinococcus multilocularis cysteine protease 0.0017 0.0017 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0142 0.0136
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Mycobacterium tuberculosis Probable reductase 0.0106 0.0582 0.4282
Brugia malayi hypothetical protein 0.0055 0.0259 0.0522
Giardia lamblia GTOR 0.0044 0.0192 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Echinococcus granulosus single minded 2 0.0035 0.0136 0.0265
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0164 0.0947 0.1924
Echinococcus multilocularis tyrosine protein kinase Blk 0.0041 0.017 0.0164
Brugia malayi MH2 domain containing protein 0.0236 0.1398 0.2844
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0211 0.0205
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0259 0.1713
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0211 0.0417
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0017 0.0029
Leishmania major beta tubulin 0.0794 0.4909 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0591 0.363 0.3626
Echinococcus granulosus integrin beta 2 0.0229 0.1352 0.2745
Brugia malayi hypothetical protein 0.0041 0.0173 0.0348
Mycobacterium ulcerans beta-lactamase 0.0035 0.0136 0.1032
Loa Loa (eye worm) tubulin alpha chain 0.0591 0.363 0.7394
Brugia malayi SPARC precursor 0.0038 0.0149 0.0299
Schistosoma mansoni smad 0.0016 0.0014 0.0022
Onchocerca volvulus 0.0055 0.0259 0.1713
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0011 0.0018
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.036 0.0354
Echinococcus multilocularis lamin dm0 0.0027 0.008 0.0074
Brugia malayi beta-lactamase 0.0035 0.0136 0.0273
Trypanosoma cruzi beta tubulin, putative 0.0794 0.4909 1
Schistosoma mansoni tubulin subunit delta 0.0203 0.1193 0.2426
Schistosoma mansoni hypothetical protein 0.0032 0.0117 0.0231
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0037 0.0145 0.0291
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0582 0.4282
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0192 0.0386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0397
Loa Loa (eye worm) ctsf protein 0.0017 0.0017 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0192 0.0378
Leishmania major beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0847 0.1721
Echinococcus multilocularis Tubulin beta 2C chain 0.0794 0.4909 0.4906
Trichomonas vaginalis tubulin gamma chain, putative 0.0203 0.1193 0.2421
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0211 0.0417
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Trypanosoma brucei trypanothione reductase 0.0047 0.0206 0.0408
Echinococcus granulosus neuropeptide receptor A26 0.0464 0.2836 0.5771
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.001
Schistosoma mansoni nuclear receptor nhr-48 0.0037 0.0145 0.0289
Giardia lamblia Beta tubulin 0.0794 0.4909 1
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0016
Loa Loa (eye worm) tubulin alpha-3 chain 0.035 0.2113 0.4302
Loa Loa (eye worm) glutathione reductase 0.0047 0.0206 0.0415
Brugia malayi prostaglandin transporter 0.0055 0.0259 0.0522
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0011 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0078 0.0405 0.0821
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0136 0.0918
Echinococcus granulosus dnaJ subfamily B 0.0403 0.245 0.4985
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0192 0.0378
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.1138 0.1132
Leishmania major beta tubulin 0.0794 0.4909 1
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0259 0.0253
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0591 0.363 0.7392
Brugia malayi protein-tyrosine kinase 0.0041 0.017 0.0341
Brugia malayi ecdysone receptor 0.0037 0.0145 0.0291
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0078 0.0405 0.0819
Echinococcus granulosus Niemann Pick C1 protein 0.0278 0.1663 0.3379
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0109 0.0216
Echinococcus granulosus Tubulin beta 2C chain 0.0794 0.4909 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0037 0.0145 0.0139
Echinococcus granulosus beta tubulin 0.0794 0.4909 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0091 0.0172
Trypanosoma cruzi epsilon tubulin, putative 0.0471 0.2875 0.5854
Loa Loa (eye worm) hypothetical protein 0.0387 0.235 0.4784
Trichomonas vaginalis tubulin alpha chain, putative 0.0794 0.4909 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0078 0.0405 0.0814
Loa Loa (eye worm) SRC-1 0.0047 0.0211 0.0425
Trypanosoma brucei zeta tubulin 0.0478 0.2924 0.5951
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0008
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0322 0.065
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0791 0.1601
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.1193 0.2421
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0158
Loa Loa (eye worm) hypothetical protein 0.0195 0.1138 0.2313
Mycobacterium ulcerans hypothetical protein 0.0035 0.0136 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.0146
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0142 0.0277
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0078 0.0405 0.0819
Schistosoma mansoni tyrosine kinase 0.0098 0.0528 0.1069
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0065 0.0132
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Loa Loa (eye worm) fibroinase 0.0017 0.0017 0.0029
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0211 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0136 0.0271
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0192 0.0378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0078 0.0405 0.0821
Loa Loa (eye worm) Smad1 0.0016 0.0014 0.0024
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Echinococcus multilocularis tubulin alpha 1C chain 0.0591 0.363 0.3626
Loa Loa (eye worm) tubulin alpha chain 0.0591 0.363 0.7394
Mycobacterium tuberculosis Conserved protein 0.0035 0.0136 0.0918
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.021
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.134 1
Brugia malayi Tubulin alpha chain 0.0591 0.363 0.7394
Echinococcus granulosus Tubulin beta 2C chain 0.0794 0.4909 1
Trypanosoma cruzi tubulin gamma chain 0.0471 0.2878 0.5859
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0694 0.1402
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0177
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0322 0.0652
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.0017
Echinococcus multilocularis epidermal growth factor receptor 0.0162 0.0931 0.0925
Brugia malayi MH2 domain containing protein 0.0016 0.0014 0.0024
Echinococcus multilocularis geminin 0.0335 0.2021 0.2016
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0017 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0848
Brugia malayi intermediate filament protein 0.0027 0.008 0.0158
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.006 0.0385
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0103 0.0559 0.0553
Echinococcus granulosus tyrosine protein kinase HCK 0.0034 0.0128 0.0248
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0136 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0438 0.0881
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Brugia malayi steroid hormone receptor 0.0078 0.0405 0.0821
Trichomonas vaginalis tubulin beta chain, putative 0.0241 0.143 0.2903
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0322 0.0645
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0269 0.2157
Brugia malayi Tyrosine-protein kinase abl-1 0.0096 0.0519 0.1053
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0046 0.0204 0.0408
Echinococcus granulosus FTZ F1 alpha 0.0078 0.0405 0.0814
Trypanosoma brucei epsilon tubulin 0.0471 0.2875 0.5852
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0348
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0065 0.0133
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0065 0.0339
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0062 0.012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0175 0.1017 0.2061
Trypanosoma brucei beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0037 0.0145 0.0283
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0061 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0142 0.0277
Mycobacterium leprae cell division protein FtsZ 0.0203 0.1193 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0091 0.0179
Echinococcus multilocularis protein patched 0.0084 0.0438 0.0432
Plasmodium vivax tubulin epsilon chain, putative 0.0471 0.2875 0.5857
Brugia malayi hypothetical protein 0.0032 0.0115 0.023
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0006 0.0008
Echinococcus multilocularis Immunoglobulin 0.0021 0.0043 0.0036
Brugia malayi tailless protein 0.0037 0.0145 0.0291
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0078 0.0405 0.0821
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0136 0.0918
Plasmodium vivax tubulin gamma chain, putative 0.0471 0.2878 0.5862
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0109 0.0218
Trypanosoma brucei alpha tubulin 0.0591 0.363 0.7392
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0142 0.0285
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0521 0.3193 0.3188
Echinococcus multilocularis roundabout 2 0.0029 0.0098 0.0092
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0017 0.0005
Echinococcus multilocularis cpg binding protein 0.003 0.0101 0.0095
Loa Loa (eye worm) hypothetical protein 0.0036 0.0142 0.0285
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0017 0.001
Trypanosoma brucei alpha tubulin 0.0591 0.363 0.7392
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0145 0.0289
Brugia malayi nuclear receptor RXR 0.0037 0.0145 0.0291
Onchocerca volvulus 0.0038 0.0149 0.0936
Toxoplasma gondii cathepsin CPL 0.0017 0.0017 0.0027
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0014 0.0008
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0149 0.0297
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.035 0.2113 0.4298
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0168 0.033
Echinococcus multilocularis musashi 0.0027 0.008 0.0074
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Brugia malayi tubulin alpha chain - mouse 0.0591 0.363 0.7394
Echinococcus granulosus tubulin subunit beta 0.0794 0.4909 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0103
Leishmania major beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0136 0.0273
Loa Loa (eye worm) cysteine protease 0.0017 0.0017 0.0029
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0029 0.0096 0.019
Brugia malayi PAS domain containing protein 0.0048 0.0215 0.0432
Echinococcus granulosus intermediate filament protein 0.0027 0.008 0.0151
Leishmania major epsilon tubulin, putative 0.0471 0.2875 0.5852
Trichomonas vaginalis tubulin beta chain, putative 0.0794 0.4909 1
Mycobacterium leprae Probable lipase LipE 0.0035 0.0136 0.0673
Schistosoma mansoni tyrosine kinase 0.0156 0.0897 0.1821
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Schistosoma mansoni thyroid hormone receptor 0.0202 0.1186 0.2411
Echinococcus granulosus tubulin alpha 0.0445 0.271 0.5515
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.003
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0091 0.0172
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0017 0.0034
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0224 0.0451
Echinococcus multilocularis ecdysone induced protein 78C 0.0078 0.0405 0.0399
Brugia malayi hypothetical protein 0.0047 0.0208 0.0419
Entamoeba histolytica tubulin family protein 0.0794 0.4909 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0054 0.0096
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0211 0.0417
Brugia malayi nuclear hormone receptor 0.0078 0.0405 0.0821
Schistosoma mansoni lamin 0.0027 0.008 0.0157
Echinococcus granulosus tubulin delta chain 0.0203 0.1193 0.2421
Onchocerca volvulus 0.0023 0.006 0.0306
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0125
Onchocerca volvulus 0.0037 0.0145 0.0909
Leishmania major beta tubulin 0.0794 0.4909 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0136 0.0918
Treponema pallidum NADH oxidase 0.0016 0.0015 0.0094
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0017 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0173 0.0346
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0145 0.0283
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0216
Mycobacterium tuberculosis Cell division protein FtsZ 0.0203 0.1193 0.8894
Loa Loa (eye worm) tubulin beta-2A chain 0.0794 0.4909 1
Echinococcus multilocularis 0.0091 0.0486 0.048
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0206 0.02
Echinococcus multilocularis integrin alpha ps 0.0032 0.0117 0.011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0198 0.0399
Schistosoma mansoni single-minded 0.0048 0.0215 0.0431
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0023
Trichomonas vaginalis tubulin, putative 0.0241 0.143 0.2903
Onchocerca volvulus 0.0078 0.0405 0.275
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0211 0.0417
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0192 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0091 0.0084
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.0204
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0259 0.1713
Plasmodium vivax vivapain-2 0.0017 0.0017 0.0034
Onchocerca volvulus 0.0241 0.143 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.0005
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0011 0.0018
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0142 0.0277
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0291 0.0586
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Brugia malayi Tubulin alpha chain 0.0203 0.1193 0.2427
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.1138 0.2317
Loa Loa (eye worm) nuclear hormone receptor 0.0037 0.0145 0.0291
Echinococcus multilocularis tubulin gamma 1 chain 0.0471 0.2878 0.2873
Echinococcus granulosus tubulin alpha 1C chain 0.0591 0.363 0.7392
Echinococcus multilocularis peroxisome assembly protein 26 0.0591 0.363 0.3626
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0022
Brugia malayi Tubulin beta chain 0.0203 0.1193 0.2427
Brugia malayi sulfakinin receptor protein 0.022 0.1299 0.2642
Echinococcus granulosus integrin alpha ps 0.0068 0.0338 0.0677
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0657 0.4845
Schistosoma mansoni DNA helicase recq5 0.0028 0.0091 0.0177
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0078 0.0405 0.0819
Leishmania major cathepsin L-like protease 0.0017 0.0017 0.0021
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0848
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0136 0.0278
Echinococcus multilocularis nuclear receptor nhr 48 0.0037 0.0145 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Echinococcus multilocularis tubulin alpha 0.0445 0.271 0.2706
Leishmania major cathepsin L-like protease 0.0063 0.0309 0.0617
Entamoeba histolytica hypothetical protein 0.0046 0.0204 0.0415
Brugia malayi hypothetical protein 0.0037 0.0145 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0436 0.0884
Brugia malayi alpha-tubulin 0.0591 0.363 0.7394
Schistosoma mansoni tyrosine kinase 0.0298 0.1787 0.3635
Toxoplasma gondii beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) tubulin alpha 2 0.0387 0.235 0.4784
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0017 0.0027
Brugia malayi isocitrate dehydrogenase 0.0031 0.0109 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0299
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0017 0.001
Echinococcus multilocularis Tubulin alpha 1 chain 0.0591 0.363 0.3626
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Trypanosoma brucei epsilon tubulin 0.0471 0.2875 0.5852
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0078 0.0405 0.0821
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0065 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0037 0.0145 0.0139
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0078 0.0151
Loa Loa (eye worm) tubulin alpha 2 0.0146 0.0833 0.1693
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0322 0.0652
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0017 0.0017
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0037 0.0145 0.0139
Echinococcus granulosus twitchin 0.0024 0.0061 0.0112
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0023 0.0062
Loa Loa (eye worm) intermediate filament protein 0.0027 0.008 0.0158
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0065 0.0058
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0065 0.0514
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Brugia malayi hypothetical protein 0.0037 0.0145 0.0291
Echinococcus granulosus tubulin epsilon chain 0.0471 0.2875 0.5852
Brugia malayi Integrin alpha pat-2 precursor 0.0151 0.0862 0.1751
Toxoplasma gondii thioredoxin reductase 0.0047 0.0206 0.0413
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0017 0.0017
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.015 0.0144
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0387 0.235 0.4784
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0046 0.0204 1
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0848
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.1138 0.2307
Loa Loa (eye worm) tubulin beta chain 0.0203 0.1193 0.2427
Schistosoma mansoni zinc finger protein 0.0037 0.0145 0.0289
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Plasmodium vivax delta tubulin, putative 0.0203 0.1193 0.2431
Schistosoma mansoni cpg binding protein 0.003 0.0101 0.0199
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0211 0.0205
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0078 0.0405 0.0821
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.006 0.0385
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0136 0.0271
Trichomonas vaginalis tubulin epsilon chain, putative 0.0591 0.363 0.7392
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0134 0.0757 0.0751
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0078 0.0405 0.0821
Loa Loa (eye worm) hypothetical protein 0.0164 0.0947 0.1925
Brugia malayi hypothetical protein 0.0161 0.0925 0.1881
Echinococcus granulosus epidermal growth factor receptor 0.0162 0.0931 0.1885
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0136 0.0273
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.1138 0.2313
Brugia malayi SRC-1 0.0047 0.0211 0.0425
Trichomonas vaginalis tubulin alpha chain, putative 0.0241 0.143 0.2903
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0582 0.4606
Echinococcus granulosus epidermal growth factor receptor 0.0298 0.1787 0.3632
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0198 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0046 0.0204 0.1428
Schistosoma mansoni tyrosine kinase 0.0103 0.0559 0.1132
Echinococcus multilocularis beta tubulin 0.0794 0.4909 0.4906
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0259 0.0515
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0179 0.0351
Schistosoma mansoni nuclear receptor 0.0037 0.0145 0.0289
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0078 0.0405 0.0399
Giardia lamblia Alpha-tubulin 0.0591 0.363 0.7387
Loa Loa (eye worm) hypothetical protein 0.0034 0.0125 0.025
Brugia malayi hypoxia-induced factor 1 0.0148 0.0847 0.1721
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.0405 0.0399
Echinococcus multilocularis protein dispatched 1 0.0095 0.0513 0.0507
Brugia malayi Nuclear hormone receptor E75 0.0037 0.0145 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.0405 0.0814
Echinococcus multilocularis integrin alpha 3 0.0116 0.064 0.0634
Loa Loa (eye worm) hypothetical protein 0.0161 0.0925 0.1881
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0142 0.029
Schistosoma mansoni survival motor neuron protein 0.0048 0.0212 0.0425
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0078 0.0405 0.0821
Toxoplasma gondii alpha-tubulin I, putative 0.0591 0.363 0.7393
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0041 0.017 0.0334
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0109 0.0194
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0694 0.0688
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0078 0.0405 0.275
Schistosoma mansoni integrin beta subunit 0.0182 0.1057 0.2148
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0125
Schistosoma mansoni cell adhesion molecule 0.0026 0.0079 0.0155
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Echinococcus multilocularis L aminoadipate semialdehyde 0.0164 0.0947 0.0941
Schistosoma mansoni follistatin 0.0038 0.0149 0.0297
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.003 0.0048
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Echinococcus granulosus tubulin alpha 1C chain 0.0591 0.363 0.7392
Schistosoma mansoni Smad4 0.0016 0.0014 0.0022
Trichomonas vaginalis tubulin epsilon chain, putative 0.0203 0.1193 0.2421
Echinococcus multilocularis cysteine protease 0.0017 0.0017 0.001
Loa Loa (eye worm) tubulin beta-4 chain 0.0794 0.4909 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Trypanosoma brucei beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0078 0.0405 0.0821
Echinococcus granulosus Tubulin alpha 1 chain 0.0591 0.363 0.7392
Echinococcus multilocularis lamin 0.0027 0.008 0.0074
Entamoeba histolytica hypothetical protein 0.0071 0.036 0.0734
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0192 0.0391
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0135 0.0262
Schistosoma mansoni vesicular amine transporter 0.0021 0.0043 0.008
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus L aminoadipate semialdehyde 0.0164 0.0947 0.1919
Schistosoma mansoni integrin alpha 0.0151 0.0862 0.1749
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Plasmodium vivax tubulin alpha chain, putative 0.0591 0.363 0.7395
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Schistosoma mansoni RAR-like nuclear receptor 0.0078 0.0405 0.0819
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Schistosoma mansoni tubulin subunit alpha 0.0203 0.1193 0.2426
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0017 0.0021
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0192 0.0378
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0002
Echinococcus granulosus Tubulin alpha 1 chain 0.0591 0.363 0.7392
Giardia lamblia Beta tubulin 0.0794 0.4909 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0471 0.2875 0.5852
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0136 0.0918
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Brugia malayi hypothetical protein 0.0055 0.0259 0.0522
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Schistosoma mansoni tubulin subunit alpha 0.0591 0.363 0.7393
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.245 0.2446
Echinococcus granulosus tubulin alpha 3 chain 0.0591 0.363 0.7392
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.1398 0.2844
Echinococcus granulosus peroxisome assembly protein 26 0.0591 0.363 0.7392
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0142 0.0283
Brugia malayi orphan nuclear receptor NR2E1 0.0037 0.0145 0.0291
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0226 0.0449
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0817 0.0811
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.0082
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0041 0.0173 0.034
Schistosoma mansoni tyrosine kinase 0.0162 0.0931 0.189
Loa Loa (eye worm) RecQ helicase 0.0041 0.0168 0.0338
Leishmania major beta tubulin 0.0794 0.4909 1
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0142 0.0283
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0212 0.0427
Trypanosoma cruzi zeta tubulin, putative 0.0478 0.2924 0.5953
Echinococcus multilocularis Tubulin beta 2C chain 0.0794 0.4909 0.4906
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Echinococcus multilocularis expressed protein 0.0038 0.0149 0.0143
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0224 0.0451
Leishmania major beta tubulin 0.0794 0.4909 1
Entamoeba histolytica protein kinase, putative 0.0034 0.0128 0.0261
Echinococcus multilocularis Niemann Pick C1 protein 0.0278 0.1663 0.1658
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.006 0.0385
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0041 0.0173 0.0348
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0078 0.0405 0.0814
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0208 0.0419
Echinococcus granulosus tubulin beta 4A class IVa 0.0794 0.4909 1
Schistosoma mansoni organic anion transporter 0.0055 0.0259 0.0521
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0438 0.0881
Mycobacterium tuberculosis Conserved protein 0.0035 0.0136 0.0918
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0109 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Echinococcus granulosus smad 0.0016 0.0014 0.0016
Leishmania major beta tubulin 0.0794 0.4909 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Schistosoma mansoni hypothetical protein 0.0335 0.2021 0.4112
Echinococcus granulosus lamin 0.0027 0.008 0.0151
Trypanosoma brucei alpha tubulin 0.0591 0.363 0.7392
Trichomonas vaginalis tubulin epsilon chain, putative 0.0794 0.4909 1
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0046 0.0204 0.1605
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0211 0.0417
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0109 0.021
Leishmania major cathepsin L-like protease 0.0063 0.0309 0.0617
Toxoplasma gondii tubulin, putative 0.0026 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0322 0.065
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0179 0.0351
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0078 0.0405 0.0814
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0065 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1026 0.208
Brugia malayi Integrin beta pat-3 precursor 0.0309 0.1856 0.3777
Echinococcus multilocularis tubulin epsilon chain 0.0471 0.2875 0.2871
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0211 0.0205
Loa Loa (eye worm) tubulin gamma chain 0.0471 0.2878 0.586
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0259 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Echinococcus multilocularis Tubulin alpha 1 chain 0.0591 0.363 0.3626
Echinococcus granulosus alpha tubulin 0.0591 0.363 0.7392
Giardia lamblia Delta tubulin 0.0203 0.1193 0.2408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0451
Loa Loa (eye worm) beta-tubulin 0.0794 0.4909 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Schistosoma mansoni tyrosine kinase 0.0098 0.0528 0.1069
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.0631 0.128
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0003 0.0007
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.023 0.1359 0.2762
Echinococcus multilocularis insulin receptor 0.0098 0.0528 0.0522
Echinococcus multilocularis tubulin alpha 3 chain 0.0591 0.363 0.3626
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0211 0.0205
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0149 0.0299
Echinococcus granulosus Tubulin beta 2C chain 0.0794 0.4909 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0091 0.0155
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0657 0.5265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Giardia lamblia Alpha-tubulin 0.0591 0.363 0.7387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Schistosoma mansoni tubulin subunit beta 0.0794 0.4909 1
Trypanosoma cruzi epsilon tubulin, putative 0.0471 0.2875 0.5854
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0014 0.0016
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0065 0.0378
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.0405 0.0399
Loa Loa (eye worm) hypothetical protein 0.035 0.2113 0.4302
Echinococcus multilocularis follistatin 0.0038 0.0149 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Schistosoma mansoni tubulin subunit alpha 0.0591 0.363 0.7393
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0657 0.4845
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0216
Trichomonas vaginalis tubulin alpha chain, putative 0.0241 0.143 0.2903
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Schistosoma mansoni nuclear hormone receptor 0.0078 0.0405 0.0819
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0014 0.0008
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0157 0.0319
Leishmania major cathepsin L-like protease 0.0017 0.0017 0.0021
Echinococcus multilocularis integrin alpha ps 0.0068 0.0338 0.0332
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0017 0.001
Echinococcus granulosus GPCR family 2 0.0016 0.0011 0.001
Echinococcus granulosus tubulin gamma 1 chain 0.0471 0.2878 0.5857
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0192 0.0384
Echinococcus granulosus Nuclear hormone receptor HR96 0.0037 0.0145 0.0283
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0206 0.0408
Schistosoma mansoni hypothetical protein 0.0022 0.0054 0.0102
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0078 0.0405 0.0821
Echinococcus multilocularis tyrosine protein kinase Srms 0.0041 0.017 0.0164
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0322 0.0316
Giardia lamblia Beta tubulin 0.0794 0.4909 1
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0103 0.0559 0.1126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0078 0.0405 0.0821
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Brugia malayi Tubulin gamma chain 0.0471 0.2878 0.586
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.012 0.0238
Trypanosoma cruzi alpha tubulin, putative 0.0591 0.363 0.7393
Loa Loa (eye worm) alpha-tubulin 0.0591 0.363 0.7394
Echinococcus multilocularis tyrosine protein kinase HCK 0.0034 0.0128 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Echinococcus granulosus nuclear receptor nhr 48 0.0037 0.0145 0.0283
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.036 0.0728
Trichomonas vaginalis tubulin, putative 0.0794 0.4909 1
Echinococcus multilocularis epidermal growth factor receptor 0.0298 0.1787 0.1782
Brugia malayi nuclear hormone receptor family member odr-7 0.0037 0.0145 0.0291
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0226 0.0455
Echinococcus multilocularis tubulin subunit beta 0.0794 0.4909 0.4906
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0445 0.271 0.5518
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0269 0.0263
Plasmodium vivax tubulin beta chain, putative 0.0794 0.4909 1
Onchocerca volvulus 0.0035 0.0136 0.0846
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.006 0.0122
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0136 0.0918
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Echinococcus multilocularis tubulin delta chain 0.0203 0.1193 0.1188
Brugia malayi nuclear hormone receptor family member nhr-6 0.0037 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0149 0.0299
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0006
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Schistosoma mansoni hypothetical protein 0.0403 0.245 0.4988
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0065 0.0102
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0162 0.0931 0.1885
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0236 0.1398 0.2844
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0577 0.1171
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0136 0.0673
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Schistosoma mansoni tubulin subunit epsilon 0.0471 0.2875 0.5854
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.1157 0.235
Entamoeba histolytica hypothetical protein 0.0071 0.036 0.0734
Onchocerca volvulus 0.0035 0.0136 0.0846
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0136 0.0273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Loa Loa (eye worm) hypothetical protein 0.0102 0.0557 0.1129
Echinococcus granulosus transcription factor Dp 1 0.0038 0.015 0.0293
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0198 0.0391
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0078 0.0405 0.0821
Loa Loa (eye worm) hypothetical protein 0.0078 0.0405 0.0821
Echinococcus granulosus Immunoglobulin 0.0021 0.0043 0.0074
Echinococcus granulosus Smad4 0.0016 0.0014 0.0016
Trichomonas vaginalis tubulin alpha chain, putative 0.0241 0.143 0.2903
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.022 0.0441
Schistosoma mansoni hypothetical protein 0.0034 0.0125 0.0249
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0017 0.0027
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0065 0.0132
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0582 0.4282
Brugia malayi Cell division protein ftsZ 0.0203 0.1193 0.2427
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0135 0.0268
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0142 0.0283
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0152 0.0281
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0215 0.1269 0.1263
Echinococcus multilocularis Smad4 0.0016 0.0014 0.0008
Echinococcus granulosus Tubulin beta 2C chain 0.0794 0.4909 1
Plasmodium falciparum thioredoxin reductase 0.0047 0.0206 0.0392
Schistosoma mansoni hypothetical protein 0.0335 0.2021 0.4112
Schistosoma mansoni tyrosine kinase 0.0019 0.003 0.0054
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0168 0.033
Plasmodium vivax tubulin alpha chain, putative 0.0591 0.363 0.7395
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.012 0.0232
Loa Loa (eye worm) alpha-tubulin 0.0591 0.363 0.7394
Echinococcus multilocularis expressed conserved protein 0.0183 0.1063 0.1058
Brugia malayi Cathepsin L-like precursor 0.0017 0.0017 0.0029
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Loa Loa (eye worm) TK protein kinase 0.0034 0.0128 0.0255
Schistosoma mansoni nuclear receptor 0.0037 0.0145 0.0289
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1523 0.3094
Echinococcus multilocularis tubulin alpha chain 0.0591 0.363 0.3626
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0043 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0322 0.0645
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0094 0.0178
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0043 0.0036
Echinococcus multilocularis tubulin alpha chain 0.0591 0.363 0.3626
Brugia malayi photoreceptor-specific nuclear receptor 0.0078 0.0405 0.0821
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0157 0.029
Echinococcus multilocularis Tubulin beta 2C chain 0.0794 0.4909 0.4906
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0269
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0226 0.0461
Leishmania major beta tubulin 0.0794 0.4909 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0269 0.0541
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.006 0.0122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0142 0.0277
Trichomonas vaginalis tubulin beta chain, putative 0.0591 0.363 0.7392
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0046 0.0204 0.1605
Entamoeba histolytica tubulin alpha-1 chain 0.0591 0.363 0.7395
Echinococcus granulosus cathepsin l1 0.0017 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0127
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.021
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0136 0.0265
Mycobacterium ulcerans hypothetical protein 0.0023 0.006 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Echinococcus granulosus thyroid hormone receptor alpha 0.0037 0.0145 0.0283
Brugia malayi CXXC zinc finger family protein 0.0028 0.0091 0.018
Trypanosoma brucei alpha tubulin, putative 0.0241 0.143 0.2903
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0017 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0037 0.0145 0.0291
Echinococcus multilocularis Immunoglobulin 0.0021 0.0043 0.0036
Brugia malayi nuclear hormone receptor 0.0037 0.0145 0.0291
Brugia malayi ecdysteroid receptor 0.0078 0.0405 0.0821
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0179
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0348
Trichomonas vaginalis tubulin gamma chain, putative 0.0794 0.4909 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0192 0.0386
Loa Loa (eye worm) acetyltransferase 0.0144 0.0817 0.1659
Brugia malayi glutathione reductase 0.0047 0.0206 0.0415
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0224 0.045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0198 0.0397
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0192 0.0185
Loa Loa (eye worm) hypothetical protein 0.0035 0.0136 0.0273
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0078 0.0405 0.0819
Echinococcus multilocularis Tubulin beta 2C chain 0.0794 0.4909 0.4906
Echinococcus multilocularis integrin beta 2 0.0229 0.1352 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0063 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.0017
Trichomonas vaginalis esterase, putative 0.0035 0.0136 0.0265
Echinococcus granulosus Tubulin beta 2C chain 0.0794 0.4909 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Schistosoma mansoni retinoic acid receptor RXR 0.0175 0.1017 0.2066
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0078 0.0405 0.0399
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0136 0.0265
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0136 0.0265
Loa Loa (eye worm) BEN-1 protein 0.0794 0.4909 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0078 0.0405 0.275
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0322 0.0657
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0136 0.013
Echinococcus granulosus neuroglian 0.0024 0.0061 0.0112
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0192 0.0384
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0204 0.0403
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0142 0.0277
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0158
Loa Loa (eye worm) hypothetical protein 0.0233 0.138 0.2807
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0192 0.0378
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0142 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0078 0.0405 0.0821
Plasmodium falciparum tubulin gamma chain 0.0471 0.2878 0.585
Echinococcus multilocularis GPCR, family 2 0.0016 0.0011 0.0005
Plasmodium falciparum tubulin epsilon chain, putative 0.0471 0.2875 0.5845
Leishmania major alpha tubulin 0.0591 0.363 0.7392
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0177
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0259 0.0522
Schistosoma mansoni tyrosine kinase 0.0209 0.1227 0.2493
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Schistosoma mansoni lamin 0.0027 0.008 0.0157
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0125 0.025
Trichomonas vaginalis tubulin, putative 0.023 0.1361 0.2763
Brugia malayi nuclear receptor NHR-67 0.0037 0.0145 0.0291
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.021
Entamoeba histolytica cysteine protease, putative 0.0017 0.0017 0.0034
Echinococcus multilocularis integrin alpha ps 0.0068 0.0338 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.097 0.1964
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0368 0.2229 0.4536
Brugia malayi beta-lactamase family protein 0.0035 0.0136 0.0273
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0109 0.0716
Plasmodium falciparum tubulin delta chain, putative 0.0203 0.1193 0.2408
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0119
Toxoplasma gondii beta-1 tubulin, putative 0.0794 0.4909 1
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0173 0.0348
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0136 0.0918
Schistosoma mansoni hypothetical protein 0.0124 0.0694 0.1407
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.0082
Echinococcus granulosus agrin 0.0038 0.0149 0.0291
Schistosoma mansoni tyrosine kinase 0.0047 0.0211 0.0423
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.006 0.0343
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0029 0.0045
Trypanosoma brucei alpha tubulin 0.0591 0.363 0.7392
Echinococcus multilocularis agrin 0.0038 0.0149 0.0143
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Mycobacterium leprae conserved hypothetical protein 0.0046 0.0204 0.1269
Loa Loa (eye worm) TK/ABL protein kinase 0.0215 0.1269 0.258
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0179 0.0364
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.016
Echinococcus multilocularis FTZ F1 alpha 0.0078 0.0405 0.0399
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0226 0.0455
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0107 0.0217
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0206 0.0413
Loa Loa (eye worm) hypothetical protein 0.0084 0.0438 0.0888
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0164 0.0947 0.1925
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0438 0.0888
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0065 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0226 0.0455
Onchocerca volvulus 0.0027 0.008 0.0449
Schistosoma mansoni coup transcription factor 0.0078 0.0405 0.0819
Plasmodium falciparum alpha tubulin 2 0.0591 0.363 0.7387
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0136 0.1032
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0259 0.0522
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0054 0.0047
Brugia malayi nuclear receptor RXR 0.0041 0.0173 0.0348
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.1523 0.3099
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Leishmania major zeta tubulin, putative 0.0478 0.2924 0.5951
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.0233
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.138 0.2801
Onchocerca volvulus 0.0035 0.0136 0.0846
Echinococcus multilocularis tubulin subunit TubB 0.0591 0.363 0.3626
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.1193 0.2421
Schistosoma mansoni intermediate filament proteins 0.0027 0.008 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Brugia malayi hypothetical protein 0.0023 0.0061 0.0118
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Trypanosoma brucei epsilon tubulin 0.0445 0.271 0.5515
Entamoeba histolytica tubulin gamma chain 0.0471 0.2878 0.5862
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0136 0.0265
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0041 0.0173 0.0346
Echinococcus multilocularis neuropeptide receptor A26 0.0464 0.2836 0.2831
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0149 0.0297
Trypanosoma brucei beta tubulin 0.0445 0.271 0.5515
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0037 0.0145 0.0909
Brugia malayi MH1 domain containing protein 0.0016 0.0014 0.0024
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0179 0.0357
Brugia malayi Tubulin alpha-2 chain 0.0591 0.363 0.7394
Onchocerca volvulus 0.0164 0.0947 0.6584
Mycobacterium ulcerans lipase LipD 0.0035 0.0136 0.1032
Leishmania major beta tubulin 0.0794 0.4909 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0078 0.0405 0.0821
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0309 0.0617
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0101 0.0546 0.11
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0203 0.1193 0.2421
Plasmodium vivax glutathione reductase, putative 0.0047 0.0206 0.042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0017 0.0021
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0091 0.0155
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0198 0.0391
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0014 0.0022
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.0023
Loa Loa (eye worm) hypothetical protein 0.0118 0.0658 0.1335
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0109 0.0216
Onchocerca volvulus 0.0055 0.0259 0.1713
Leishmania major cathepsin L-like protease 0.0017 0.0017 0.0021
Schistosoma mansoni DNA helicase recq1 0.0028 0.0091 0.0177
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0198 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0017 0.0021
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0107 0.0204
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.0405 0.0814
Echinococcus multilocularis tubulin alpha 1C chain 0.0591 0.363 0.3626
Onchocerca volvulus 0.0048 0.0212 0.1382
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.008 0.0158
Echinococcus multilocularis neuropeptide s receptor 0.0464 0.2836 0.2831
Loa Loa (eye worm) hypothetical protein 0.0038 0.0149 0.0299
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.138 0.1374
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0179 0.0351
Echinococcus granulosus integrin alpha ps 0.0032 0.0117 0.0225
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0078 0.0405 0.0819
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0192 0.0378
Brugia malayi Tubulin alpha-2 chain 0.0591 0.363 0.7394
Loa Loa (eye worm) hypothetical protein 0.0037 0.0145 0.0291
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0023 0.0017
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0274 0.0552
Trypanosoma brucei tubulin gamma chain 0.0471 0.2878 0.5857
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0226 0.0433
Onchocerca volvulus 0.0037 0.0145 0.0909
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0206 0.1446
Trypanosoma cruzi zeta tubulin, putative 0.0478 0.2924 0.5953
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0078 0.0405 0.0821
Plasmodium vivax vivapain-2 0.0017 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Schistosoma mansoni alpha tubulin 0.0591 0.363 0.7393
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0522
Brugia malayi hypothetical protein 0.005 0.0226 0.0456
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0109 0.0218
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0259 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0136 0.0265
Brugia malayi MH2 domain containing protein 0.0016 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.0591 0.363 0.7394
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.006 0.0122
Schistosoma mansoni steroid hormone receptor ad4bp 0.0078 0.0405 0.0819
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0136 0.0265

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 39.7 uM Cytotoxicity against human HT-29 cells by MTT assay ChEMBL. 18996624
IC50 (functional) = 47 uM Cytotoxicity against human Bel7402 cells by MTT assay ChEMBL. 18996624

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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