Detailed information for compound 1041712

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.345 | Formula: C18H18F2N2O2
  • H donors: 1 H acceptors: 2 LogP: 3.22 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)C(=O)c1cc(ccc1O)c1ccc(cc1F)F
  • InChi: 1S/C18H18F2N2O2/c1-21-6-8-22(9-7-21)18(24)15-10-12(2-5-17(15)23)14-4-3-13(19)11-16(14)20/h2-5,10-11,23H,6-9H2,1H3
  • InChiKey: AIPBQISMSWXLSG-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Toxoplasma gondii preprocathepsin c precursor, putative 0.0031 0.0039 0.0302
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0089 0.0089
Schistosoma mansoni myelin transcription factor 1 myt1 0.0167 0.0688 0.0688
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0027 0.0019 0.0076
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0297 0.1236
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0031 0.0039 0.0191
Brugia malayi hypothetical protein 0.0148 0.0596 0.2353
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0119 0.046 0.1815
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0123 0.0123
Brugia malayi TAR-binding protein 0.0063 0.0188 0.0744
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0108 0.0405 0.0941
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0248 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0358 0.0358
Mycobacterium tuberculosis Probable lipase LipE 0.0291 0.128 0.1459
Schistosoma mansoni ap endonuclease 0.0057 0.0163 0.0163
Echinococcus multilocularis calpain A 0.0178 0.074 0.074
Onchocerca volvulus 0.0093 0.0332 0.1425
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0123 0.0123
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) fibroinase 0.0098 0.0358 0.0831
Plasmodium falciparum serine repeat antigen 1 0.0031 0.0039 0.0191
Echinococcus granulosus laminin 0.0026 0.0016 0.0016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0031 0.0039 0.009
Brugia malayi Fli-1 protein 0.0235 0.1014 0.4005
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Echinococcus multilocularis cathepsin L 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0412 0.1858 0.1858
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0216 0.1683
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0283 0.1118
Schistosoma mansoni hypothetical protein 0.0903 0.4207 0.4207
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0004 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0163 0.038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0291 0.128 0.1459
Loa Loa (eye worm) hypothetical protein 0.0051 0.0133 0.0309
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0123 0.0123
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0019 0.0074
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0466 0.0531
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0163 0.068
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0388
Echinococcus granulosus caspase 2 0.003 0.0034 0.0034
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0244 0.0244
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0123 0.0286
Loa Loa (eye worm) ctsf protein 0.0098 0.0358 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Echinococcus multilocularis microtubule associated protein 2 0.2114 1 1
Onchocerca volvulus Deterin homolog 0.0093 0.0332 0.1425
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0157 0.0642 0.2482
Plasmodium falciparum serine repeat antigen 3 0.0031 0.0039 0.0191
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0188 0.0744
Echinococcus granulosus intermediate filament protein 0.011 0.0415 0.0415
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.1273 0.63
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.128 0.533
Echinococcus multilocularis calpain family protein 1, d 0.0123 0.0478 0.0478
Brugia malayi neuropeptide F receptor 0.0049 0.0123 0.0486
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0123 0.0123
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0028 0.0028
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0052 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus calpain A 0.0063 0.0191 0.0191
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0079 0.0079
Echinococcus granulosus mitogen activated protein kinase 3 0.0157 0.0642 0.0642
Toxoplasma gondii HEAT repeat-containing protein 0.0086 0.0303 0.2366
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0123 0.0123
Brugia malayi phosphofructokinase 0.0121 0.0466 0.1842
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.0168 0.0664
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0148 0.0598 0.1389
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0123 0.0486
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0589 0.2708 0.2708
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0147 0.0591 0.2536
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Trypanosoma cruzi cysteine proteinase, putative 0.0058 0.0168 0.0594
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.006 0.006
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0384 0.1728 0.1728
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0123 0.0123
Echinococcus granulosus SAM and MBT domain containing protein 0.0147 0.0591 0.0591
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0082 0.0082
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0182 0.0761 0.0761
Echinococcus multilocularis inositol monophosphatase 1 0.011 0.0413 0.0413
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Leishmania major glycosyl hydrolase-like protein 0.0042 0.009 0.0447
Trichomonas vaginalis glucosylceramidase, putative 0.0363 0.1627 0.6773
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0123 0.0486
Echinococcus multilocularis neutral alpha glucosidase AB 0.0113 0.0429 0.0429
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0157 0.0642 0.5017
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0188 0.0438
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0123 0.0486
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0123 0.0123
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0045 0.0353
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0496 0.2263 0.894
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0117 0.045 0.1718
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.046 0.046
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0157 0.0642 0.3178
Brugia malayi Cathepsin L-like precursor 0.0027 0.0019 0.0074
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0004 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0163 0.0186
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Echinococcus multilocularis geminin 0.2059 0.9734 0.9734
Schistosoma mansoni bromodomain containing protein 0.0134 0.053 0.053
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0064 0.0194 0.0958
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0228 0.0951
Trichomonas vaginalis sucrase-isomaltase, putative 0.0113 0.0429 0.1787
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0183 0.0761
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0503 0.1926
Brugia malayi beta-lactamase 0.0291 0.128 0.5058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0168 0.0699
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0167 0.0688 0.0688
Echinococcus granulosus neuropeptide s receptor 0.1893 0.8942 0.8942
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0765
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Brugia malayi PHD-finger family protein 0.0054 0.0147 0.058
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0429 0.1634
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0463 0.2105 0.2105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.128 0.128
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0031 0.0039 0.0191
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0045 0.0224
Onchocerca volvulus 0.0071 0.0228 0.0981
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0052 0.0052
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0061 0.0183 0.4421
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Brugia malayi RNA, U transporter 1 0.0246 0.1065 0.4208
Onchocerca volvulus 0.0291 0.128 0.5498
Toxoplasma gondii LsmAD domain-containing protein 0.0128 0.0503 0.3925
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0268 0.1117
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Schistosoma mansoni survival motor neuron protein 0.0096 0.0347 0.0347
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0171 0.0397
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0565 0.0644
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Brugia malayi hypothetical protein 0.0128 0.0503 0.1985
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0052 0.0256
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0291 0.128 0.2005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0019 0.0078
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0045 0.0223
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0031 0.0039 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0168 0.0699
Plasmodium falciparum serine repeat antigen 2 0.0031 0.0039 0.0191
Schistosoma mansoni ets-related 0.0235 0.1014 0.1014
Entamoeba histolytica calpain large subunit domain III containing protein 0.0044 0.01 0.0496
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Brugia malayi cathepsin L-like precursor 0.0071 0.0228 0.0902
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0052 0.0132
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0565 0.2353
Echinococcus multilocularis hypothetical protein 0.0063 0.0191 0.0191
Echinococcus multilocularis calpain 0.0063 0.0191 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0183 0.0761
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Echinococcus multilocularis inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Echinococcus multilocularis sex peptide receptor 0.0049 0.0123 0.0123
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0061 0.0183 0.0904
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0123 0.0123
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0082 0.0082
Echinococcus multilocularis cathepsin L 0.0031 0.0039 0.0039
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Leishmania major hypothetical protein, conserved 0.0128 0.0503 0.2486
Loa Loa (eye worm) hypothetical protein 0.0157 0.0641 0.1488
Loa Loa (eye worm) hypothetical protein 0.0082 0.0283 0.0658
Giardia lamblia Cathepsin L-like protease 0.0031 0.0039 0.0065
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0031 0.0039 0.0191
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0157 0.0641 0.253
Onchocerca volvulus 0.0147 0.0591 0.2536
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0466 0.2307
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0238
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0283 0.0283
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0422 0.0422
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0123 0.0123
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.026 0.026
Onchocerca volvulus 0.0082 0.0283 0.1216
Plasmodium falciparum phd finger protein, putative 0.0029 0.0026 0.0127
Leishmania major carbonic anhydrase-like protein 0.0119 0.046 0.2273
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0082 0.0191
Schistosoma mansoni hypothetical protein 0.0027 0.0019 0.0019
Onchocerca volvulus 0.0049 0.0123 0.0528
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0565 0.4416
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0031 0.0039 0.0191
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0696
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Leishmania major cysteine peptidase A (CPA) 0.0098 0.0358 0.1769
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0026 0.0016 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0035 0.0145
Plasmodium falciparum serine repeat antigen 5 0.0031 0.0039 0.0191
Onchocerca volvulus 0.0148 0.0596 0.2559
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0171 0.0397
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0185 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0363 0.1627 0.6773
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0031 0.0039 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.037 0.037
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Loa Loa (eye worm) hypothetical protein 0.0147 0.0591 0.1372
Trichomonas vaginalis importin beta-1, putative 0.007 0.0225 0.0935
Schistosoma mansoni cathepsin s 0.0027 0.0019 0.0019
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0093 0.0332 0.0332
Onchocerca volvulus Cathepsin L homolog 0.0031 0.0039 0.0166
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Echinococcus multilocularis protein patched 0.0042 0.0089 0.0089
Brugia malayi Glycosyl hydrolases family 31 protein 0.0509 0.2323 0.9176
Loa Loa (eye worm) FKBP5 protein 0.0446 0.2021 0.4697
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0552 0.2532 0.2532
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0082 0.0082
Brugia malayi CHD4 protein 0.0029 0.0028 0.011
Trypanosoma brucei glycosyl hydrolase-like protein 0.0042 0.009 0.0447
Echinococcus multilocularis importin subunit beta 1 0.0086 0.0303 0.0303
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0163 0.0809
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0123 0.0123
Echinococcus multilocularis lamin 0.011 0.0415 0.0415
Brugia malayi cathepsin B-like cysteine proteinase 0.0552 0.2532 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0528 0.1228
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Onchocerca volvulus 0.0032 0.0043 0.0185
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0178 0.074 0.074
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1858 0.8777 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0148 0.0595 0.1383
Trypanosoma brucei kinesin, putative 0.0044 0.01 0.0495
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Trichomonas vaginalis Importin beta-1 subunit, putative 0.007 0.0225 0.0935
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0283 0.0283
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0336 0.0336
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0466 0.1084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Loa Loa (eye worm) hypothetical protein 0.0086 0.0303 0.0704
Echinococcus granulosus calpain 0.0063 0.0191 0.0191
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0463 0.2105 0.2105
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0061 0.0183 0.0722
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.2124
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0026 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0291 0.128 0.6334
Leishmania major alpha glucosidase II subunit, putative 0.0113 0.0429 0.2124
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0356 0.0356
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0061 0.0183 0.0425
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Onchocerca volvulus 0.0098 0.0358 0.1536
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0123 0.0123
Brugia malayi Bromodomain containing protein 0.0033 0.0049 0.0195
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.1273 0.63
Brugia malayi calpain 5 0.0044 0.01 0.0396
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Brugia malayi MH2 domain containing protein 0.0134 0.0528 0.2088
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0167 0.0688 0.1598
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0078
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0565 0.0885
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0157 0.0641 0.0641
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0509 0.2323 0.5397
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0147 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus granulosus cathepsin L 0.0058 0.0168 0.0168
Echinococcus granulosus cathepsin l1 0.0098 0.0358 0.0358
Echinococcus granulosus somatostatin receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0079 0.031
Loa Loa (eye worm) hypothetical protein 0.0062 0.0186 0.0433
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0064 0.0194 0.1513
Brugia malayi Dopamine receptor protein 1 0.0049 0.0123 0.0486
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0089 0.0313 0.0728
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.157
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Loa Loa (eye worm) cathepsin B 0.0192 0.081 0.1881
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus mitogen activated protein kinase 0.0157 0.0642 0.0642
Schistosoma mansoni calpain (C02 family) 0.0063 0.0191 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0089 0.0372
Giardia lamblia Hypothetical protein 0.0031 0.0039 0.0065
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0061 0.0183 0.0425
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0027 0.0019 0.0045
Echinococcus granulosus FK506 binding protein 2 0.0061 0.0183 0.0183
Onchocerca volvulus 0.0031 0.0039 0.0166
Schistosoma mansoni gabp alpha 0.0077 0.026 0.026
Leishmania major importin beta-1 subunit, putative 0.007 0.0225 0.1111
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0031 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.006 0.006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0536 0.2453 0.5699
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0958
Echinococcus multilocularis protein dispatched 1 0.0048 0.0118 0.0118
Trichomonas vaginalis inositol monophosphatase, putative 0.011 0.0413 0.172
Onchocerca volvulus 0.0049 0.0123 0.0528
Plasmodium vivax ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0466 0.2307
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0086 0.0303 0.1498
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0123 0.0123
Schistosoma mansoni inositol monophosphatase 0.011 0.0413 0.0413
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0466 0.0466
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0163 0.3954
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0466 0.1084
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0291 0.128 0.5498
Brugia malayi cathepsin F-like cysteine proteinase 0.0031 0.0039 0.0153
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0026 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Brugia malayi Ets-domain containing protein 0.0077 0.026 0.1026
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0089 0.0208
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Onchocerca volvulus 0.0098 0.0358 0.1536
Brugia malayi hypothetical protein 0.0083 0.0285 0.1127
Brugia malayi hypothetical protein 0.0469 0.2131 0.8416
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0358 0.0831
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0163 0.0576
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Brugia malayi Pre-SET motif family protein 0.0448 0.2033 0.8031
Brugia malayi MAP kinase sur-1 0.0157 0.0642 0.2538
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0446 0.2021 0.7985
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni hypothetical protein 0.0339 0.1512 0.1512
Trypanosoma brucei importin beta-1 subunit, putative 0.0086 0.0303 0.1498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Schistosoma mansoni inositol monophosphatase 0.011 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Onchocerca volvulus 0.0049 0.0123 0.0528
Schistosoma mansoni hypothetical protein 0.0093 0.0332 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 1
Echinococcus granulosus peregrin 0.0033 0.0049 0.0049
Trypanosoma cruzi ISWI complex protein 0.0032 0.0042 0.0093
Echinococcus granulosus calpain 5 0.0063 0.0191 0.0191
Echinococcus granulosus fmrfamide receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 0.797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Brugia malayi Augmenter of liver regeneration 0.0034 0.0052 0.0205
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.009 0.0357
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0192 0.081 0.4005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.009 0.0286
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0028 0.0028
Toxoplasma gondii cathepsin CPL 0.0098 0.0358 0.2794
Schistosoma mansoni cathepsin B (C01 family) 0.0031 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Loa Loa (eye worm) calpain 5 0.0044 0.01 0.0233
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0356 0.1405
Brugia malayi jmjC domain containing protein 0.0093 0.0336 0.1327
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0413 0.172
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.006 0.006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0079 0.0327
Trypanosoma cruzi major cysteine proteinase, putative 0.0078 0.0261 0.0963
Loa Loa (eye worm) hypothetical protein 0.0066 0.0206 0.0479
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0052 0.0132
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Echinococcus multilocularis Chromobox protein 3 0.0023 0.000000012859 0.000000012859
Plasmodium vivax vivapain-2 0.0098 0.0358 0.177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Toxoplasma gondii cathepsin CPC1 0.0031 0.0039 0.0302
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0183 0.0761
Leishmania major hypothetical protein, conserved 0.0291 0.128 0.6334
Brugia malayi jmjC domain containing protein 0.004 0.0082 0.0325
Echinococcus granulosus importin subunit beta 1 0.0086 0.0303 0.0303
Echinococcus multilocularis SAM and MBT domain containing protein 0.0147 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0079 0.0264
Echinococcus granulosus polycomb protein SCMH1 0.0147 0.0591 0.0591
Mycobacterium tuberculosis Probable lipase LipD 0.0291 0.128 0.1459
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0058 0.0164 0.0164
Onchocerca volvulus 0.003 0.0034 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0168 0.0831
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0363 0.0363
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0163 0.0808
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0123 0.0123
Echinococcus granulosus snurportin 1 0.0923 0.4304 0.4304
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0039 0.0161
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0058 0.0168 0.0594
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0429 0.1634
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0031 0.0039 0.0191
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0123 0.0123
Echinococcus multilocularis cysteine protease 0.0098 0.0358 0.0358
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0123 0.0486
Loa Loa (eye worm) hypothetical protein 0.011 0.0415 0.0963
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0157 0.0641 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis zinc finger protein 0.0043 0.0093 0.0093
Echinococcus granulosus dnaJ subfamily B 0.0412 0.1858 0.1858
Echinococcus multilocularis Tolloid protein 1 0.0026 0.0016 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0446 0.2021 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1663 0.7842 0.7842
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0031 0.0039 0.0191
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0168 0.0831
Trichomonas vaginalis maltase-glucoamylase, putative 0.0113 0.0429 0.1787
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0098 0.0358 0.177
Trypanosoma brucei hypothetical protein, conserved 0.0061 0.0183 0.0904
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0123 0.0123
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0061 0.0183 0.0722
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Echinococcus multilocularis peregrin 0.0033 0.0049 0.0049
Brugia malayi Cytochrome P450 family protein 0.0052 0.0138 0.0544
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 0.797
Echinococcus granulosus histone acetyltransferase MYST2 0.0167 0.0688 0.0688
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0123 0.0286
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0 0.0001
Plasmodium vivax vivapain-1 0.0058 0.0168 0.0831
Schistosoma mansoni Mername-AA248 (C02 family) 0.0063 0.0191 0.0191
Leishmania major peptidylprolyl isomerase-like protein 0.0446 0.2021 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0031 0.0039 0.0191
Schistosoma mansoni fk506 binding protein 0.0061 0.0183 0.0183
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0093 0.0332 0.0332
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.128 0.128
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0061 0.0183 0.0904
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0026 0.0016 0.0036
Echinococcus granulosus neuropeptide receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0923 0.4304 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0031 0.0039 0.0191
Loa Loa (eye worm) MBCTL1 0.0167 0.0688 0.1598
Echinococcus granulosus survival motor neuron protein 1 0.0469 0.2131 0.2131
Trypanosoma brucei PAB1-binding protein , putative 0.0128 0.0503 0.2486
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0297 0.1236
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0042 0.009 0.0389
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0123 0.0123
Leishmania major hypothetical protein, conserved 0.0034 0.0052 0.0256
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Echinococcus granulosus allatostatin A receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0446 0.2021 0.4697
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0031 0.0039 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0016 0.0067
Trichomonas vaginalis esterase, putative 0.0291 0.128 0.533
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0098 0.0358 0.2798
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0358 0.1536
Giardia lamblia Hypothetical protein 0.0061 0.0183 0.0787
Trichomonas vaginalis fk506 binding protein, putative 0.0061 0.0183 0.0761
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus cathepsin l1 0.0071 0.0228 0.0228
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0123 0.0486
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis neuropeptide receptor A26 0.1893 0.8942 0.8942
Brugia malayi Latrophilin receptor protein 2 0.0157 0.0641 0.253
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0356 0.1759
Loa Loa (eye worm) carbonic anhydrase 3 0.0119 0.046 0.1068
Schistosoma mansoni chromobox protein 0.0141 0.0565 0.0565
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Schistosoma mansoni hypothetical protein 0.0043 0.0095 0.0095
Echinococcus multilocularis fk506 binding protein 0.0446 0.2021 0.2021
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0123 0.0486
Trypanosoma brucei glucosidase, putative 0.0113 0.0429 0.2124
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0466 0.3642
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0045 0.2472
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.046 0.1754
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis calpain 5 0.0063 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi latrophilin 2 splice variant baaae 0.0339 0.1512 0.5973
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0167 0.0688 0.2716
Schistosoma mansoni zinc finger protein 0.0043 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma brucei cysteine peptidase C (CPC) 0.0192 0.081 0.4005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Echinococcus multilocularis survival motor neuron protein 1 0.0469 0.2131 0.2131
Brugia malayi Dopamine receptor 0.0049 0.0123 0.0486
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) inositol-1 0.011 0.0413 0.096
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0079 0.0079
Loa Loa (eye worm) RNA binding protein 0.0063 0.0188 0.0438
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.009 0.0377
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Onchocerca volvulus Arrow homolog 0.0026 0.0016 0.0067
Echinococcus multilocularis cathepsin b 0.0552 0.2532 0.2532
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0113 0.0429 0.1787
Echinococcus multilocularis serotonin receptor 0.0049 0.0123 0.0123
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0123 0.0123
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0123 0.0123
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0182 0.0761 0.3765
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0291 0.128 0.1459
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0062 0.0186 0.08
Brugia malayi G protein-coupled receptor 0.0049 0.0123 0.0486
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0182 0.0761 0.0867
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Trypanosoma brucei hypothetical protein, conserved 0.0291 0.128 0.6334
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0163 0.0256
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0095 0.0221
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0446 0.2021 1
Plasmodium vivax calpain, putative 0.0063 0.0191 0.0944
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0016 0.0061
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0034 0.0145
Brugia malayi G-protein coupled receptor 0.0049 0.0123 0.0486
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0556 0.0556
Echinococcus granulosus GTP binding nuclear protein Ran 0.0064 0.0194 0.0194
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.0565 0.1313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Loa Loa (eye worm) hypothetical protein 0.0248 0.1076 0.25
Loa Loa (eye worm) intermediate filament protein 0.011 0.0415 0.0963
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus jumonji domain containing protein 0.004 0.0079 0.0079
Plasmodium vivax serine-repeat antigen (SERA) 0.0031 0.0039 0.0191
Mycobacterium tuberculosis Probable esterase LipL 0.0291 0.128 0.1459
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0168 0.0594
Echinococcus granulosus chromobox protein 1 0.0141 0.0565 0.0565
Schistosoma mansoni calpain-7 (C02 family) 0.0066 0.0206 0.0206
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0446 0.2021 1
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0045 0.2472
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.0761 0.0761
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0089 0.0089
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0079 0.0388
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0052 0.012
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Brugia malayi mbt repeat family protein 0.0147 0.0591 0.2333
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Brugia malayi hypothetical protein 0.0248 0.1076 0.425
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0589 0.2708 0.2708
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0098 0.0358 0.177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0031 0.0039 0.0039
Schistosoma mansoni lamin 0.011 0.0415 0.0415
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Loa Loa (eye worm) calpain 0.0063 0.0191 0.0443
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0052 0.0405
Echinococcus granulosus geminin 0.2059 0.9734 0.9734
Plasmodium vivax importin-beta 2, putative 0.0086 0.0303 0.1498
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0093 0.0332 0.1311
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.009 0.0286
Trypanosoma brucei carbonic anhydrase-like protein 0.0119 0.046 0.2273
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0157 0.0642 0.1493
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Echinococcus multilocularis musashi 0.011 0.0415 0.0415
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.009 0.0377
Echinococcus multilocularis cpg binding protein 0.0038 0.0071 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0123 0.0123
Brugia malayi Calcitonin receptor-like protein seb-1 0.0496 0.2263 0.894
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0054 0.0054
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis somatostatin receptor 0.0049 0.0123 0.0123
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) beta-lactamase 0.0291 0.128 0.2975
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0064 0.0194 0.0194
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0061 0.0183 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Onchocerca volvulus Huntingtin homolog 0.0248 0.1076 0.462
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0123 0.0286
Echinococcus multilocularis polycomb protein SCMH1 0.0147 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0042 0.009 0.021
Echinococcus multilocularis laminin 0.0026 0.0016 0.0016
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0466 0.0466
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0043 0.01
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0061 0.0183 0.0183
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0123 0.0123
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0052 0.0256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0016 0.0121
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0415 0.0963
Echinococcus granulosus lamin dm0 0.011 0.0415 0.0415
Echinococcus multilocularis expressed conserved protein 0.0092 0.0327 0.0327
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0061 0.0183 0.0425
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0771
Loa Loa (eye worm) hypothetical protein 0.0051 0.0134 0.0312
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Plasmodium vivax vivapain-2 0.0098 0.0358 0.177
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0591 0.0591
Brugia malayi calpain 7 0.0063 0.0191 0.0754
Entamoeba histolytica cysteine proteinase 1, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Trypanosoma cruzi cruzipain precursor, putative 0.0144 0.058 0.2233
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0943
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0016 0.0061
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0 0.0001
Schistosoma mansoni hypothetical protein 0.0029 0.0026 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0123 0.0123
Schistosoma mansoni calpain-7 (C02 family) 0.0066 0.0206 0.0206
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0123 0.0123
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0123 0.0123
Brugia malayi sulfakinin receptor protein 0.0049 0.0123 0.0486
Schistosoma mansoni alpha glucosidase 0.0113 0.0429 0.0429
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Onchocerca volvulus 0.0049 0.0123 0.0528
Schistosoma mansoni cpg binding protein 0.0038 0.0071 0.0071
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0556 0.0556
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0358 0.1536
Trypanosoma cruzi ISWI complex protein 0.0032 0.0042 0.0093
Loa Loa (eye worm) hypothetical protein 0.0061 0.0183 0.0425
Trypanosoma brucei ISWI complex protein 0.0032 0.0042 0.0207
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0028 0.0065
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0045 0.0224
Schistosoma mansoni hypothetical protein 0.2059 0.9734 0.9734
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0842
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0466 0.1084
Echinococcus multilocularis 0.0061 0.0183 0.0183
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Plasmodium falciparum cysteine proteinase falcipain 1 0.0058 0.0168 0.0831
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.02 0.02
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0123 0.0123
Trichomonas vaginalis fk506-binding protein, putative 0.0446 0.2021 0.8414
Mycobacterium ulcerans beta-lactamase 0.0291 0.128 0.2005
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0027 0.0019 0.0074
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0167 0.0688 0.0688
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0157 0.0641 0.0641
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0123 0.0286
Echinococcus multilocularis calpain 7 (C02 family) 0.0063 0.0191 0.0191
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.011 0.0413 0.3227
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.128 0.5021
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0291 0.128 0.1459
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0188 0.0188
Entamoeba histolytica cysteine protease, putative 0.0098 0.0358 0.177
Brugia malayi follicle stimulating hormone receptor 0.0536 0.2453 0.9689
Mycobacterium ulcerans short chain dehydrogenase 0.1358 0.6386 1
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0384 0.1728 0.1728
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0332
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0123 0.0286
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0045 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Brugia malayi Importin beta-1 subunit 0.0086 0.0303 0.1196
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Echinococcus multilocularis mitogen activated protein kinase 0.0157 0.0642 0.0642
Echinococcus granulosus inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Trypanosoma cruzi cysteine protease, putative 0.0058 0.0168 0.0594
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0123 0.0123
Brugia malayi mbt repeat family protein 0.0147 0.0591 0.2333
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0466 0.0466
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0448 0.2033 0.4724
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0123 0.0486
Loa Loa (eye worm) latrophilin receptor protein 2 0.0157 0.0641 0.1488
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi cathepsin Z-like cysteine proteinase 0.0031 0.0039 0.0153
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0061 0.0183 0.0904
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0463 0.2105 0.4891
Onchocerca volvulus 0.0049 0.0123 0.0528
Schistosoma mansoni calpain C (C02 family) 0.0063 0.0191 0.0191
Onchocerca volvulus 0.051 0.2329 1
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0446 0.2021 0.2021
Leishmania major fk506-binding protein 1-like protein 0.0446 0.2021 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.128 0.533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.009 0.0377
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0079 0.0327
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0248 0.0248
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0188 0.0438
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0098 0.0358 0.0831
Echinococcus granulosus cathepsin b 0.0552 0.2532 0.2532
Echinococcus granulosus zinc finger protein 0.0043 0.0093 0.0093
Echinococcus multilocularis apoptotic protease activating factor 1 0.003 0.0034 0.0034
Schistosoma mansoni zinc finger protein 0.0032 0.0042 0.0042
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0123 0.0123
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0163 0.0809
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0123 0.0123
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0167 0.0688 0.0688
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0011 0.0044
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Brugia malayi calpain family protein 1 0.0167 0.0688 0.272
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0079 0.0079
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Schistosoma mansoni microtubule-associated protein tau 0.2114 1 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0623
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0126 0.0494 0.0494
Entamoeba histolytica Ran family GTPase 0.0064 0.0194 0.0958
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0123 0.0123
Brugia malayi AKH receptor 0.0049 0.0123 0.0486
Trypanosoma brucei antigen, putative 0.0063 0.0191 0.0943
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0004 0.0005
Brugia malayi hypothetical protein 0.0111 0.0422 0.1665
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0031 0.0039 0.0039
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Giardia lamblia Hypothetical protein 0.0031 0.0039 0.0065
Toxoplasma gondii ABC1 family protein 0.0291 0.128 1
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0045 0.0224
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0771
Brugia malayi fibroinase precursor 0.0031 0.0039 0.0153
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0031 0.0039 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus serotonin receptor 0.0049 0.0123 0.0123
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0026 0.0127
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0089 0.0089
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0031 0.0039 0.0191
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0157 0.0642 0.3178
Plasmodium falciparum serine repeat antigen 4 0.0031 0.0039 0.0191
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0163 0.068
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0358 0.177
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0183 0.0761
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Onchocerca volvulus 0.0098 0.0358 0.1536
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Schistosoma mansoni adenoreceptor 0.0049 0.0123 0.0123
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0123 0.0528
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0026 0.0201
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0123 0.0123
Schistosoma mansoni inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0123 0.0123
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.046 0.046
Plasmodium vivax serine-repeat antigen (SERA) 0.0031 0.0039 0.0191
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Brugia malayi putative neuropeptide receptor 0.0049 0.0123 0.0486
Trypanosoma brucei protein kinase, putative 0.0157 0.0642 0.3178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis carbonic anhydrase II 0.0119 0.046 0.046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0079 0.0388
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus Tolloid protein 1 0.0026 0.0016 0.0016
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0079 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0463 0.2105 0.2105
Schistosoma mansoni cathepsin F (C01 family) 0.0071 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 0.797
Echinococcus granulosus cathepsin b 0.0552 0.2532 0.2532
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0958
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.011 0.0413 1
Echinococcus granulosus expressed conserved protein 0.0092 0.0327 0.0327
Trichomonas vaginalis Importin beta-1 subunit, putative 0.007 0.0225 0.0935
Onchocerca volvulus 0.011 0.0415 0.178
Onchocerca volvulus 0.0088 0.031 0.1333
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0031 0.0039 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Schistosoma mansoni ap endonuclease 0.0057 0.0163 0.0163
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0466 0.2307
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0642 0.2482
Loa Loa (eye worm) calpain family protein 1 0.0167 0.0688 0.16
Echinococcus granulosus cpg binding protein 0.0038 0.0071 0.0071
Trichomonas vaginalis ran, putative 0.0064 0.0194 0.0806
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0422 0.0422
Echinococcus granulosus neuropeptide receptor A26 0.1893 0.8942 0.8942
Mycobacterium ulcerans lipase LipD 0.0291 0.128 0.2005
Brugia malayi Cathepsin L-like cysteine proteinase 0.0071 0.0228 0.0902
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0091 0.0324 0.0752
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.006
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.026 0.0604
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi chromobox protein homolog 3 0.0079 0.0268 0.106
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0192 0.081 0.3148
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0696
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0031 0.0039 0.0161
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0031 0.0039 0.0191
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0336 0.0336
Echinococcus multilocularis snurportin 1 0.0923 0.4304 0.4304
Brugia malayi Bromodomain containing protein 0.0158 0.0647 0.2554
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.1273 0.63
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0096 0.0347 0.0347
Echinococcus granulosus cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Brugia malayi Bromodomain containing protein 0.008 0.0272 0.1073
Loa Loa (eye worm) hypothetical protein 0.0128 0.0503 0.1168
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0297 0.1276
Echinococcus granulosus chromobox protein 1 0.0141 0.0565 0.0565
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0358 0.177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus tar DNA binding protein 0.0063 0.0188 0.0188
Brugia malayi Melatonin receptor type 1A 0.0049 0.0123 0.0486
Brugia malayi Serotonin receptor 0.0049 0.0123 0.0486
Echinococcus granulosus cathepsin L cysteine proteinase 0.0098 0.0358 0.0358
Entamoeba histolytica myo-inositol monophosphatase, putative 0.011 0.0413 0.2044
Schistosoma mansoni hypothetical protein 0.0058 0.0164 0.0164
Onchocerca volvulus Alhambra homolog 0.0029 0.0026 0.0111
Onchocerca volvulus 0.0104 0.0387 0.1662
Brugia malayi 6-phosphofructokinase 0.0121 0.0466 0.1842
Trypanosoma cruzi cysteine proteinase, putative 0.0058 0.0168 0.0594
Brugia malayi SET domain containing protein 0.0026 0.0015 0.0058
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Plasmodium falciparum importin beta, putative 0.0086 0.0303 0.1498
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0446 0.2021 0.3165
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.046 0.1754
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Loa Loa (eye worm) hypothetical protein 0.0339 0.1512 0.3514
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0503 0.1926
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0026 0.0026
Trichomonas vaginalis immunophilin, putative 0.0446 0.2021 0.8414
Echinococcus granulosus lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0347 0.1369
Plasmodium vivax unspecified product 0.0058 0.0168 0.0831
Loa Loa (eye worm) hypothetical protein 0.0248 0.1076 0.25
Echinococcus granulosus cysteine protease 0.0058 0.0168 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Brugia malayi Ets-domain containing protein 0.0077 0.026 0.1026
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0061 0.0183 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0268 0.1117
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis beta LACTamase domain containing family member 0.0291 0.128 0.128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0031 0.0039 0.0161
Loa Loa (eye worm) hypothetical protein 0.0167 0.0688 0.16
Trypanosoma cruzi importin beta-1 subunit, putative 0.007 0.0225 0.082
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0123 0.0123
Echinococcus granulosus beta LACTamase domain containing family member 0.0291 0.128 0.128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) fli-1 protein 0.0235 0.1014 0.2356
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0016 0.0121
Echinococcus granulosus Chromobox protein 3 0.0023 0.000000012859 0.000000012859
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0163 0.0646
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0123 0.0123
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.037 0.037
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.02 0.156
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0123 0.0286
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Brugia malayi PHD-finger family protein 0.0029 0.0026 0.0102
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0052 0.0405
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.006 0.006
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Schistosoma mansoni immunophilin 0.0384 0.1728 0.1728
Toxoplasma gondii exonuclease III APE 0.0057 0.0163 0.1277
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0123 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0158 0.0656
Schistosoma mansoni hypothetical protein 0.2059 0.9734 0.9734
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0138 0.032
Loa Loa (eye worm) hypothetical protein 0.0051 0.0133 0.0309
Echinococcus granulosus inositol monophosphatase 1 0.011 0.0413 0.0413
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0061 0.0183 0.0183
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0163 0.0808
Brugia malayi 6-phosphofructokinase 0.0121 0.0466 0.1842
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0163 0.069
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0238
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0446 0.2021 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0387 0.0899
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0085 0.0296 0.0688
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0525 0.2402 0.5582
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Brugia malayi Inositol-1 0.011 0.0413 0.1632
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0123 0.0486
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Loa Loa (eye worm) hypothetical protein 0.0123 0.0478 0.111
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0466 0.0466
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0031 0.0039 0.0191
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0163 0.0809
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0045 0.0353
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0119 0.046 0.1068
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.2044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0413 0.172
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis GPCR, family 2 0.0157 0.0641 0.0641
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.081 0.081
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Plasmodium vivax unspecified product 0.0031 0.0039 0.0191
Mycobacterium ulcerans hypothetical protein 0.0291 0.128 0.2005
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Onchocerca volvulus 0.0096 0.0347 0.1488
Brugia malayi larval opioid receptor 0.0049 0.0123 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0031 0.0039 0.0161
Mycobacterium leprae Probable lipase LipE 0.0291 0.128 1
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0358 0.1349
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.128 0.5021
Echinococcus granulosus cathepsin L 0.0031 0.0039 0.0039
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0045 0.0224
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0143 0.0143
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Plasmodium falciparum serine repeat antigen 7 0.0031 0.0039 0.0191
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0031 0.0039 0.009
Echinococcus granulosus hypothetical protein 0.0049 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0061 0.0183 0.4421
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0063 0.0191 0.0685
Leishmania major kinesin, putative 0.0044 0.01 0.0495
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0119 0.046 0.1815
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0123 0.0123
Giardia lamblia Cathepsin L-like protease 0.0031 0.0039 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Echinococcus multilocularis mitogen activated protein kinase 3 0.0157 0.0642 0.0642
Schistosoma mansoni chromobox protein 0.0141 0.0565 0.0565
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) cysteine protease 0.0098 0.0358 0.0831
Echinococcus multilocularis cysteine protease 0.0098 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Onchocerca volvulus 0.011 0.0415 0.178
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0058 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Schistosoma mansoni cathepsin S (C01 family) 0.0031 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0097 0.0356 0.0826
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Schistosoma mansoni hypothetical protein 0.0032 0.0042 0.0042
Brugia malayi Cathepsin L-like precursor 0.0071 0.0228 0.0902
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Loa Loa (eye worm) calpain family protein 1 0.0123 0.0478 0.111
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.009 0.0448
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0123 0.0123
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0327
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0113 0.0429 0.0998
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.0208
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0061 0.0183 0.1427
Schistosoma mansoni cpg binding protein 0.0038 0.0071 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0079 0.0079
Schistosoma mansoni alpha-glucosidase 0.0438 0.1984 0.1984
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0157 0.0642 0.3178
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0163 0.0163
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.0168 0.0664
Brugia malayi CHE-14 protein 0.0042 0.0089 0.0353
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0466 0.073
Brugia malayi calpain family protein 1 0.0167 0.0688 0.272
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Heterochromatin protein 1 0.0141 0.0565 0.2233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Echinococcus granulosus neuropeptide receptor 0.0049 0.0123 0.0123
Brugia malayi Dopamine receptor protein 2 0.0049 0.0123 0.0486
Loa Loa (eye worm) hypothetical protein 0.0552 0.2532 0.5882
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0028 0.0028
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0123 0.0123
Onchocerca volvulus Cathepsin F homolog 0.0098 0.0358 0.1536
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Schistosoma mansoni cpg binding protein 0.0032 0.0043 0.0043
Toxoplasma gondii hypothetical protein 0.0027 0.0019 0.0151
Loa Loa (eye worm) hypothetical protein 0.0496 0.2263 0.5259
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.026 0.026
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0446 0.2021 0.8414
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0123 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.081 0.337
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0591 0.0591
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Trypanosoma cruzi kinesin, putative 0.0044 0.01 0.0324
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Fibulin-1 precursor 0.0026 0.0016 0.0061
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0061 0.0183 0.0183
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Brugia malayi cathepsin L precursor 0.0031 0.0039 0.0153
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0227 0.0227
Schistosoma mansoni myosin xvIII 0.0049 0.0123 0.0123
Schistosoma mansoni intermediate filament proteins 0.011 0.0415 0.0415
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0565 0.2353
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Echinococcus multilocularis fibrillin 1 0.0026 0.0016 0.0016
Toxoplasma gondii aldehyde dehydrogenase 0.0182 0.0761 0.5945
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0079 0.0079
Schistosoma mansoni immunophilin 0.0446 0.2021 0.2021
Loa Loa (eye worm) hypothetical protein 0.0469 0.2131 0.495
Giardia lamblia Encystation-specific protease 0.0031 0.0039 0.0065
Onchocerca volvulus 0.0026 0.0013 0.0055
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0079 0.0079
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0163 0.0808
Loa Loa (eye worm) hypothetical protein 0.008 0.0272 0.0633
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 0.797
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0031 0.0039 0.0065
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0446 0.2021 0.2021
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0035 0.0145
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Brugia malayi Serotonin receptor 0.0049 0.0123 0.0486
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0163 0.0576
Schistosoma mansoni lipoxygenase 0.0054 0.015 0.015
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0026 0.0201
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Brugia malayi RNA binding protein 0.0063 0.0188 0.0744
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0415 0.1637
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0123 0.0123
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Brugia malayi Cell death protein 3 precursor 0.003 0.0034 0.0133
Echinococcus granulosus neutral alpha glucosidase AB 0.0113 0.0429 0.0429
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0123 0.0123
Mycobacterium ulcerans hypothetical protein 0.0024 0.0004 0.0007
Schistosoma mansoni cathepsin C 0.0031 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0358 0.0358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0463 0.2105 0.2105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Entamoeba histolytica hypothetical protein 0.0031 0.0039 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0045 0.0224
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Plasmodium falciparum serine repeat antigen 9 0.0031 0.0039 0.0191
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0446 0.2021 0.2021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0123 0.0123
Echinococcus multilocularis lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0052 0.0052
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0446 0.2021 0.8414
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Onchocerca volvulus 0.0291 0.128 0.5498
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0525 0.2402 0.949
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0123 0.0286
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0358 0.0358
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Echinococcus multilocularis neuropeptide s receptor 0.1893 0.8942 0.8942
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.011 0.0413 0.0647
Plasmodium falciparum carbonic anhydrase 0.0027 0.0019 0.0096
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.2044
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0123 0.0123
Schistosoma mansoni ran 0.0064 0.0194 0.0194
Schistosoma mansoni immunophilin 0.0446 0.2021 0.2021
Onchocerca volvulus 0.0098 0.0358 0.1536
Trypanosoma cruzi kinesin, putative 0.0044 0.01 0.0324
Onchocerca volvulus 0.0061 0.0183 0.0785
Toxoplasma gondii cathepsin CPC2 0.0031 0.0039 0.0302
Echinococcus granulosus calpain 7 C02 family 0.0063 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0098 0.0358 0.0831
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Entamoeba histolytica hypothetical protein 0.0023 0 0.0001
Brugia malayi beta-lactamase family protein 0.0291 0.128 0.5058
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0171 0.0674
Echinococcus multilocularis caspase 2 0.003 0.0034 0.0034
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0228 0.113
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0052 0.0256
Loa Loa (eye worm) bromodomain containing protein 0.0037 0.0066 0.0153
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0446 0.2021 1
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0528 0.1228
Leishmania major GTP-binding protein, putative 0.0064 0.0194 0.0958
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0031 0.0039 0.0153
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0642 0.2482
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0446 0.2021 1
Entamoeba histolytica cysteine proteinase 2 0.0058 0.0168 0.0831
Leishmania major hypothetical protein, conserved 0.0032 0.0042 0.0207
Brugia malayi hypothetical protein 0.0089 0.0313 0.1238
Schistosoma mansoni ran 0.0064 0.0194 0.0194
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0034 0.0034
Mycobacterium tuberculosis Probable hydrolase 0.0291 0.128 0.1459
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni hypothetical protein 0.003 0.0034 0.0034
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0045 0.0353
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0182 0.0761 0.0761
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Onchocerca volvulus Huntingtin homolog 0.0248 0.1076 0.462
Echinococcus granulosus lamin 0.011 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni histamine h1 receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.01 0.037 0.0859
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.037 0.037
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.1858 0.1858
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni importin beta-1 0.0086 0.0303 0.0303
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0088 0.031 0.031
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0466 0.1781
Plasmodium vivax vivapain-3 0.0058 0.0168 0.0831
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.1273 0.6252
Brugia malayi Pre-SET motif family protein 0.0065 0.02 0.0789
Onchocerca volvulus 0.0049 0.0123 0.0528
Brugia malayi Cathepsin L-like precursor 0.0071 0.0228 0.0902
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis histone acetyltransferase MYST2 0.0167 0.0688 0.0688
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0004 0.0022
Plasmodium falciparum serine repeat antigen 8 0.0031 0.0039 0.0191
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0552 0.2532 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0098 0.0358 0.0408
Schistosoma mansoni eyes absent homolog 0.0089 0.0313 0.0313
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0463 0.2105 0.8314
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0093 0.0332 0.1311
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0291 0.128 0.5058
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi CXXC zinc finger family protein 0.0032 0.0043 0.017
Loa Loa (eye worm) mbt repeat family protein 0.0147 0.0591 0.1372
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0079 0.0182
Entamoeba histolytica hypothetical protein 0.007 0.0225 0.1112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0016 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0228 0.0951
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0019 0.0043
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.02 0.02
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.015 0.015
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0496 0.2263 0.5259
Brugia malayi hypothetical protein 0.003 0.0034 0.0133
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Plasmodium falciparum serine repeat antigen 6 0.0031 0.0039 0.0191
Plasmodium vivax SET domain protein, putative 0.0065 0.02 0.0988
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0158 0.0656
Plasmodium falciparum cysteine proteinase falcipain 3 0.0098 0.0358 0.177
Echinococcus multilocularis serotonin receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0026 0.0026
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0446 0.2021 1
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis cathepsin b 0.0552 0.2532 0.2532
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 1
Brugia malayi GnHR receptor homolog 0.0049 0.0123 0.0486
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0157 0.0642 0.2482
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0358 0.1413
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0061 0.0183 0.0653
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Plasmodium vivax unspecified product 0.0027 0.0019 0.0093
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Brugia malayi G-protein coupled receptor 0.0049 0.0123 0.0486
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.015 0.015
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0123 0.0123
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0004 0.0033
Mycobacterium ulcerans esterase/lipase LipP 0.0291 0.128 0.2005
Trypanosoma cruzi major cysteine proteinase, putative 0.0031 0.0039 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0291 0.128 0.2975
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0356 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0313 0.0728
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0148 0.0596 0.1384
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0358 0.0358
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis lamin dm0 0.011 0.0415 0.0415
Echinococcus granulosus GPCR family 2 0.0157 0.0641 0.0641
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.037 0.037
Echinococcus granulosus cathepsin L cysteine protease 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0923 0.4304 0.4304
Echinococcus granulosus calpain A 0.0178 0.074 0.074
Onchocerca volvulus 0.0294 0.1297 0.5569
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0027 0.0019 0.0076
Schistosoma mansoni patched 1 0.0042 0.0089 0.0089
Echinococcus multilocularis chromobox protein 1 0.0141 0.0565 0.0565
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi cathepsin Z-like cysteine proteinase 0.0031 0.0039 0.0153
Brugia malayi beta-lactamase family protein 0.0291 0.128 0.5058
Giardia lamblia Kinase, CMGC MAPK 0.0157 0.0642 0.309
Brugia malayi ORL1-like opioid receptor 0.0049 0.0123 0.0486
Echinococcus multilocularis chromobox protein 1 0.0141 0.0565 0.0565
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0113 0.0429 0.1787
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Schistosoma mansoni hypothetical protein 0.0111 0.0422 0.0422
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Brugia malayi neuropeptide F receptor 0.0049 0.0123 0.0486
Echinococcus granulosus carbonic anhydrase II 0.0119 0.046 0.046
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0446 0.2021 0.2021
Brugia malayi RE15519p 0.0049 0.0123 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0039 0.0161
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0093 0.0332 0.0332
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0061 0.0183 0.0904
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.0761 0.0761
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.157
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0078
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0061 0.0183 0.0722
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0268 0.1152
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.3353
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0079 0.0079
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0123 0.0123
Echinococcus granulosus apoptotic protease activating factor 1 0.003 0.0034 0.0034
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0123 0.0528
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0045 0.0188
Mycobacterium ulcerans hypothetical protein 0.0061 0.0183 0.0286
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Onchocerca volvulus Glucosylceramidase homolog 0.0345 0.1538 0.6605
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0031 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Entamoeba histolytica protein kinase, putative 0.0046 0.0107 0.0529
Mycobacterium tuberculosis Probable oxidoreductase 0.1358 0.6386 0.7276
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0446 0.2021 0.7985
Onchocerca volvulus 0.0061 0.0183 0.0785
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.2124
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Schistosoma mansoni carbonic anhydrase 0.0027 0.0019 0.0019
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Schistosoma mansoni lamin 0.011 0.0415 0.0415
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 1
Brugia malayi intermediate filament protein 0.011 0.0415 0.1637
Loa Loa (eye worm) hypothetical protein 0.0384 0.1728 0.4015
Brugia malayi Glycosyl hydrolases family 31 protein 0.0113 0.0429 0.1696
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Mycobacterium leprae conserved hypothetical protein 0.0291 0.128 1
Trichomonas vaginalis set domain proteins, putative 0.051 0.2329 0.9694
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0143 0.0143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni egf-like domain protein 0.0026 0.0016 0.0016
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0078
Onchocerca volvulus 0.0098 0.0358 0.1536
Onchocerca volvulus 0.0024 0.0004 0.0019
Toxoplasma gondii cathepsin B 0.0192 0.081 0.6323
Echinococcus granulosus sex peptide receptor 0.0049 0.0123 0.0123
Brugia malayi cathepsin L-like cysteine proteinase 0.0031 0.0039 0.0153
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0004 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0157 0.0641 0.0641
Onchocerca volvulus 0.0098 0.0358 0.1536
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0422 0.0422
Onchocerca volvulus 0.0023 0.000000012859 0.000000055218
Schistosoma mansoni alpha-glucosidase 0.0438 0.1984 0.1984
Onchocerca volvulus 0.0098 0.0358 0.1536
Echinococcus granulosus orexin receptor type 2 0.0049 0.0123 0.0123
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0126 0.0494 0.0494

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 16.22 uM/L Growth inhibition of human Ishikawa cells ChEMBL. 19515562
IC50 (functional) = 229.91 uM/L Growth inhibition of human A549 cells ChEMBL. 19515562

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 19515562

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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