Detailed information for compound 1055480

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 346.371 | Formula: C19H20F2N2O2
  • H donors: 1 H acceptors: 2 LogP: 3.58 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)C(=O)c1cc(ccc1O)c1ccc(cc1F)F
  • InChi: 1S/C19H20F2N2O2/c1-2-22-7-9-23(10-8-22)19(25)16-11-13(3-6-18(16)24)15-5-4-14(20)12-17(15)21/h3-6,11-12,24H,2,7-10H2,1H3
  • InChiKey: PXEWZYGVGMCMAA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0446 0.2021 1
Leishmania major hypothetical protein, conserved 0.0032 0.0042 0.0207
Entamoeba histolytica cysteine proteinase 2 0.0058 0.0168 0.0831
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Mycobacterium tuberculosis Probable hydrolase 0.0291 0.128 0.1459
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0034 0.0034
Schistosoma mansoni ran 0.0064 0.0194 0.0194
Brugia malayi hypothetical protein 0.0089 0.0313 0.1238
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0045 0.0353
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Schistosoma mansoni hypothetical protein 0.003 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0182 0.0761 0.0761
Onchocerca volvulus Huntingtin homolog 0.0248 0.1076 0.462
Echinococcus granulosus lamin 0.011 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni histamine h1 receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.1858 0.1858
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.01 0.037 0.0859
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0088 0.031 0.031
Schistosoma mansoni importin beta-1 0.0086 0.0303 0.0303
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0466 0.1781
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Plasmodium vivax vivapain-3 0.0058 0.0168 0.0831
Brugia malayi Pre-SET motif family protein 0.0065 0.02 0.0789
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.1273 0.6252
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Cathepsin L-like precursor 0.0071 0.0228 0.0902
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis histone acetyltransferase MYST2 0.0167 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Plasmodium falciparum serine repeat antigen 8 0.0031 0.0039 0.0191
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0004 0.0022
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0098 0.0358 0.0408
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0552 0.2532 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Schistosoma mansoni eyes absent homolog 0.0089 0.0313 0.0313
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0463 0.2105 0.8314
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0093 0.0332 0.1311
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0291 0.128 0.5058
Loa Loa (eye worm) mbt repeat family protein 0.0147 0.0591 0.1372
Brugia malayi CXXC zinc finger family protein 0.0032 0.0043 0.017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0358 0.0358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0463 0.2105 0.2105
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Entamoeba histolytica hypothetical protein 0.0031 0.0039 0.0191
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0045 0.0224
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Plasmodium falciparum serine repeat antigen 9 0.0031 0.0039 0.0191
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0446 0.2021 0.2021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0123 0.0123
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0446 0.2021 0.8414
Onchocerca volvulus 0.0291 0.128 0.5498
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0052 0.0052
Echinococcus multilocularis lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0525 0.2402 0.949
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0123 0.0286
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.011 0.0413 0.0647
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Echinococcus multilocularis neuropeptide s receptor 0.1893 0.8942 0.8942
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0358 0.0358
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.2044
Plasmodium falciparum carbonic anhydrase 0.0027 0.0019 0.0096
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0123 0.0123
Schistosoma mansoni ran 0.0064 0.0194 0.0194
Schistosoma mansoni immunophilin 0.0446 0.2021 0.2021
Onchocerca volvulus 0.0098 0.0358 0.1536
Trypanosoma cruzi kinesin, putative 0.0044 0.01 0.0324
Onchocerca volvulus 0.0061 0.0183 0.0785
Toxoplasma gondii cathepsin CPC2 0.0031 0.0039 0.0302
Echinococcus granulosus calpain 7 C02 family 0.0063 0.0191 0.0191
Brugia malayi beta-lactamase family protein 0.0291 0.128 0.5058
Entamoeba histolytica hypothetical protein 0.0023 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0098 0.0358 0.0831
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0052 0.0256
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0228 0.113
Echinococcus multilocularis caspase 2 0.003 0.0034 0.0034
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0171 0.0674
Loa Loa (eye worm) bromodomain containing protein 0.0037 0.0066 0.0153
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0446 0.2021 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0528 0.1228
Leishmania major GTP-binding protein, putative 0.0064 0.0194 0.0958
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0031 0.0039 0.0153
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0642 0.2482
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Brugia malayi cathepsin L precursor 0.0031 0.0039 0.0153
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0227 0.0227
Schistosoma mansoni intermediate filament proteins 0.011 0.0415 0.0415
Schistosoma mansoni myosin xvIII 0.0049 0.0123 0.0123
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0565 0.2353
Echinococcus multilocularis fibrillin 1 0.0026 0.0016 0.0016
Toxoplasma gondii aldehyde dehydrogenase 0.0182 0.0761 0.5945
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0079 0.0079
Schistosoma mansoni immunophilin 0.0446 0.2021 0.2021
Loa Loa (eye worm) hypothetical protein 0.0469 0.2131 0.495
Giardia lamblia Encystation-specific protease 0.0031 0.0039 0.0065
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0163 0.0808
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0079 0.0079
Onchocerca volvulus 0.0026 0.0013 0.0055
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0031 0.0039 0.0065
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0446 0.2021 0.2021
Loa Loa (eye worm) hypothetical protein 0.008 0.0272 0.0633
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 0.797
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0035 0.0145
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Schistosoma mansoni lipoxygenase 0.0054 0.015 0.015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0163 0.0576
Brugia malayi Serotonin receptor 0.0049 0.0123 0.0486
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Brugia malayi RNA binding protein 0.0063 0.0188 0.0744
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0026 0.0201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0415 0.1637
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus neutral alpha glucosidase AB 0.0113 0.0429 0.0429
Brugia malayi Cell death protein 3 precursor 0.003 0.0034 0.0133
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0123 0.0123
Mycobacterium ulcerans hypothetical protein 0.0024 0.0004 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni cathepsin C 0.0031 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Loa Loa (eye worm) calpain family protein 1 0.0123 0.0478 0.111
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.009 0.0448
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0123 0.0123
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0327
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0113 0.0429 0.0998
Schistosoma mansoni cpg binding protein 0.0038 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.0208
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0061 0.0183 0.1427
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0123 0.0123
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0123 0.0123
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0079 0.0079
Schistosoma mansoni alpha-glucosidase 0.0438 0.1984 0.1984
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0157 0.0642 0.3178
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0163 0.0163
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Brugia malayi CHE-14 protein 0.0042 0.0089 0.0353
Brugia malayi calpain family protein 1 0.0167 0.0688 0.272
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.0168 0.0664
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0466 0.073
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0552 0.2532 0.5882
Echinococcus granulosus neuropeptide receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Brugia malayi Dopamine receptor protein 2 0.0049 0.0123 0.0486
Brugia malayi Heterochromatin protein 1 0.0141 0.0565 0.2233
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Onchocerca volvulus Cathepsin F homolog 0.0098 0.0358 0.1536
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0123 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0028 0.0028
Schistosoma mansoni cpg binding protein 0.0032 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Toxoplasma gondii hypothetical protein 0.0027 0.0019 0.0151
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0496 0.2263 0.5259
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.081 0.337
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0123 0.0123
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0446 0.2021 0.8414
Mycobacterium ulcerans aldehyde dehydrogenase 0.0182 0.0761 0.1192
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0591 0.0591
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Trypanosoma cruzi kinesin, putative 0.0044 0.01 0.0324
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni hypothetical protein 0.0061 0.0183 0.0183
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0123 0.0123
Brugia malayi Fibulin-1 precursor 0.0026 0.0016 0.0061
Schistosoma mansoni carbonic anhydrase 0.0027 0.0019 0.0019
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Schistosoma mansoni lamin 0.011 0.0415 0.0415
Brugia malayi intermediate filament protein 0.011 0.0415 0.1637
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 1
Giardia lamblia Cathepsin B precursor 0.0192 0.081 0.3928
Brugia malayi Glycosyl hydrolases family 31 protein 0.0113 0.0429 0.1696
Loa Loa (eye worm) hypothetical protein 0.0384 0.1728 0.4015
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Mycobacterium leprae conserved hypothetical protein 0.0291 0.128 1
Trichomonas vaginalis set domain proteins, putative 0.051 0.2329 0.9694
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0143 0.0143
Schistosoma mansoni egf-like domain protein 0.0026 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0078
Onchocerca volvulus 0.0098 0.0358 0.1536
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0123 0.0123
Toxoplasma gondii cathepsin B 0.0192 0.081 0.6323
Onchocerca volvulus 0.0024 0.0004 0.0019
Brugia malayi cathepsin L-like cysteine proteinase 0.0031 0.0039 0.0153
Echinococcus granulosus sex peptide receptor 0.0049 0.0123 0.0123
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0004 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0157 0.0641 0.0641
Onchocerca volvulus 0.0098 0.0358 0.1536
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0422 0.0422
Onchocerca volvulus 0.0023 0.000000012859 0.000000055218
Schistosoma mansoni alpha-glucosidase 0.0438 0.1984 0.1984
Onchocerca volvulus 0.0098 0.0358 0.1536
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0126 0.0494 0.0494
Echinococcus granulosus orexin receptor type 2 0.0049 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0111 0.0422 0.0422
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0113 0.0429 0.1787
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Onchocerca volvulus 0.0049 0.0123 0.0528
Brugia malayi neuropeptide F receptor 0.0049 0.0123 0.0486
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Echinococcus granulosus carbonic anhydrase II 0.0119 0.046 0.046
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Brugia malayi RE15519p 0.0049 0.0123 0.0486
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0446 0.2021 0.2021
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0039 0.0161
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0061 0.0183 0.0904
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0093 0.0332 0.0332
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.157
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.0761 0.0761
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0078
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0268 0.1152
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.3353
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0061 0.0183 0.0722
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0079 0.0079
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0123 0.0123
Echinococcus granulosus apoptotic protease activating factor 1 0.003 0.0034 0.0034
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0123 0.0528
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0045 0.0188
Mycobacterium ulcerans hypothetical protein 0.0061 0.0183 0.0286
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Onchocerca volvulus Glucosylceramidase homolog 0.0345 0.1538 0.6605
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0031 0.0039 0.0039
Entamoeba histolytica protein kinase, putative 0.0046 0.0107 0.0529
Mycobacterium tuberculosis Probable oxidoreductase 0.1358 0.6386 0.7276
Onchocerca volvulus 0.0061 0.0183 0.0785
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0446 0.2021 0.7985
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.2124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0031 0.0039 0.0161
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0291 0.128 0.2975
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0148 0.0596 0.1384
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0089 0.0313 0.0728
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0358 0.0358
Echinococcus multilocularis lamin dm0 0.011 0.0415 0.0415
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus granulosus GPCR family 2 0.0157 0.0641 0.0641
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.037 0.037
Echinococcus granulosus cathepsin L cysteine protease 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0923 0.4304 0.4304
Onchocerca volvulus 0.0294 0.1297 0.5569
Echinococcus granulosus calpain A 0.0178 0.074 0.074
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0027 0.0019 0.0076
Schistosoma mansoni patched 1 0.0042 0.0089 0.0089
Echinococcus multilocularis chromobox protein 1 0.0141 0.0565 0.0565
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi cathepsin Z-like cysteine proteinase 0.0031 0.0039 0.0153
Giardia lamblia Kinase, CMGC MAPK 0.0157 0.0642 0.309
Brugia malayi beta-lactamase family protein 0.0291 0.128 0.5058
Echinococcus multilocularis chromobox protein 1 0.0141 0.0565 0.0565
Brugia malayi ORL1-like opioid receptor 0.0049 0.0123 0.0486
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Entamoeba histolytica hypothetical protein 0.007 0.0225 0.1112
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0079 0.0182
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0228 0.0951
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0016 0.0036
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0019 0.0043
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.015 0.015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.02 0.02
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0496 0.2263 0.5259
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Brugia malayi hypothetical protein 0.003 0.0034 0.0133
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Plasmodium falciparum serine repeat antigen 6 0.0031 0.0039 0.0191
Plasmodium falciparum cysteine proteinase falcipain 3 0.0098 0.0358 0.177
Plasmodium vivax SET domain protein, putative 0.0065 0.02 0.0988
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0158 0.0656
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0026 0.0026
Echinococcus multilocularis serotonin receptor 0.0049 0.0123 0.0123
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0446 0.2021 1
Echinococcus multilocularis cathepsin b 0.0552 0.2532 0.2532
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Brugia malayi GnHR receptor homolog 0.0049 0.0123 0.0486
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0123 0.0123
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0004 0.0022
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0157 0.0642 0.2482
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0358 0.1413
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0061 0.0183 0.0653
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Plasmodium vivax unspecified product 0.0027 0.0019 0.0093
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0079 0.0079
Brugia malayi G-protein coupled receptor 0.0049 0.0123 0.0486
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0004 0.0033
Mycobacterium ulcerans esterase/lipase LipP 0.0291 0.128 0.2005
Trypanosoma cruzi major cysteine proteinase, putative 0.0031 0.0039 0.0079
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.015 0.015
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0079 0.0388
Echinococcus granulosus Tolloid protein 1 0.0026 0.0016 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Onchocerca volvulus 0.0049 0.0123 0.0528
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0079 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0463 0.2105 0.2105
Schistosoma mansoni cathepsin F (C01 family) 0.0071 0.0228 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0446 0.2021 0.797
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0958
Echinococcus granulosus cathepsin b 0.0552 0.2532 0.2532
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.011 0.0413 1
Echinococcus granulosus expressed conserved protein 0.0092 0.0327 0.0327
Trichomonas vaginalis Importin beta-1 subunit, putative 0.007 0.0225 0.0935
Onchocerca volvulus 0.0088 0.031 0.1333
Onchocerca volvulus 0.011 0.0415 0.178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0031 0.0039 0.0191
Schistosoma mansoni ap endonuclease 0.0057 0.0163 0.0163
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0466 0.2307
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0642 0.2482
Loa Loa (eye worm) calpain family protein 1 0.0167 0.0688 0.16
Echinococcus granulosus cpg binding protein 0.0038 0.0071 0.0071
Trichomonas vaginalis ran, putative 0.0064 0.0194 0.0806
Echinococcus granulosus neuropeptide receptor A26 0.1893 0.8942 0.8942
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0422 0.0422
Brugia malayi Cathepsin L-like cysteine proteinase 0.0071 0.0228 0.0902
Mycobacterium ulcerans lipase LipD 0.0291 0.128 0.2005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0771
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0045 0.0224
Brugia malayi fibroinase precursor 0.0031 0.0039 0.0153
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0031 0.0039 0.0191
Echinococcus granulosus serotonin receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0026 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0031 0.0039 0.0191
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0089 0.0089
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0157 0.0642 0.3178
Plasmodium falciparum serine repeat antigen 4 0.0031 0.0039 0.0191
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0163 0.068
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0358 0.177
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0123 0.0123
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0183 0.0761
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Onchocerca volvulus 0.0098 0.0358 0.1536
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Schistosoma mansoni adenoreceptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0123 0.0528
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0026 0.0201
Schistosoma mansoni inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0123 0.0123
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0123 0.0123
Plasmodium vivax serine-repeat antigen (SERA) 0.0031 0.0039 0.0191
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.046 0.046
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Brugia malayi putative neuropeptide receptor 0.0049 0.0123 0.0486
Trypanosoma brucei protein kinase, putative 0.0157 0.0642 0.3178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Echinococcus multilocularis carbonic anhydrase II 0.0119 0.046 0.046
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.128 0.533
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.009 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0079 0.0327
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0248 0.0248
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0188 0.0438
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0098 0.0358 0.0831
Echinococcus granulosus cathepsin b 0.0552 0.2532 0.2532
Echinococcus multilocularis apoptotic protease activating factor 1 0.003 0.0034 0.0034
Echinococcus granulosus zinc finger protein 0.0043 0.0093 0.0093
Schistosoma mansoni zinc finger protein 0.0032 0.0042 0.0042
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0163 0.0809
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0123 0.0123
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0123 0.0123
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0011 0.0044
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0167 0.0688 0.0688
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Brugia malayi calpain family protein 1 0.0167 0.0688 0.272
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0079 0.0079
Schistosoma mansoni microtubule-associated protein tau 0.2114 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0126 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0623
Entamoeba histolytica Ran family GTPase 0.0064 0.0194 0.0958
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0123 0.0123
Trypanosoma brucei antigen, putative 0.0063 0.0191 0.0943
Brugia malayi AKH receptor 0.0049 0.0123 0.0486
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0004 0.0005
Brugia malayi hypothetical protein 0.0111 0.0422 0.1665
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0157 0.0641 0.0641
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0031 0.0039 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Giardia lamblia Hypothetical protein 0.0031 0.0039 0.0065
Toxoplasma gondii ABC1 family protein 0.0291 0.128 1
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Trichomonas vaginalis fk506-binding protein, putative 0.0446 0.2021 0.8414
Mycobacterium ulcerans beta-lactamase 0.0291 0.128 0.2005
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0027 0.0019 0.0074
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0167 0.0688 0.0688
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0157 0.0641 0.0641
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0123 0.0286
Echinococcus multilocularis calpain 7 (C02 family) 0.0063 0.0191 0.0191
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.011 0.0413 0.3227
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0291 0.128 0.1459
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.128 0.5021
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0188 0.0188
Entamoeba histolytica cysteine protease, putative 0.0098 0.0358 0.177
Mycobacterium ulcerans short chain dehydrogenase 0.1358 0.6386 1
Brugia malayi follicle stimulating hormone receptor 0.0536 0.2453 0.9689
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0384 0.1728 0.1728
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0332
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0045 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Brugia malayi Importin beta-1 subunit 0.0086 0.0303 0.1196
Trypanosoma cruzi cysteine protease, putative 0.0058 0.0168 0.0594
Echinococcus granulosus inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Echinococcus multilocularis mitogen activated protein kinase 0.0157 0.0642 0.0642
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Brugia malayi mbt repeat family protein 0.0147 0.0591 0.2333
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0123 0.0123
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0466 0.0466
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Leishmania major cathepsin L-like protease 0.0144 0.058 0.2868
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0448 0.2033 0.4724
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0123 0.0486
Loa Loa (eye worm) latrophilin receptor protein 2 0.0157 0.0641 0.1488
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0061 0.0183 0.0904
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi cathepsin Z-like cysteine proteinase 0.0031 0.0039 0.0153
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0463 0.2105 0.4891
Onchocerca volvulus 0.0049 0.0123 0.0528
Onchocerca volvulus 0.051 0.2329 1
Leishmania major fk506-binding protein 1-like protein 0.0446 0.2021 1
Schistosoma mansoni calpain C (C02 family) 0.0063 0.0191 0.0191
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0446 0.2021 0.2021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0031 0.0039 0.009
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Echinococcus granulosus hypothetical protein 0.0049 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0061 0.0183 0.4421
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0063 0.0191 0.0685
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0119 0.046 0.1815
Leishmania major kinesin, putative 0.0044 0.01 0.0495
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0123 0.0123
Giardia lamblia Cathepsin L-like protease 0.0031 0.0039 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Echinococcus multilocularis mitogen activated protein kinase 3 0.0157 0.0642 0.0642
Schistosoma mansoni chromobox protein 0.0141 0.0565 0.0565
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) cysteine protease 0.0098 0.0358 0.0831
Echinococcus multilocularis cysteine protease 0.0098 0.0358 0.0358
Onchocerca volvulus 0.011 0.0415 0.178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0123 0.0123
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0058 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Schistosoma mansoni cathepsin S (C01 family) 0.0031 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Loa Loa (eye worm) hypothetical protein 0.0097 0.0356 0.0826
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Brugia malayi Cathepsin L-like precursor 0.0071 0.0228 0.0902
Schistosoma mansoni hypothetical protein 0.0032 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Brugia malayi 6-phosphofructokinase 0.0121 0.0466 0.1842
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0163 0.069
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0238
Loa Loa (eye worm) hypothetical protein 0.0104 0.0387 0.0899
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0446 0.2021 1
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0642 0.0642
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Loa Loa (eye worm) hypothetical protein 0.0085 0.0296 0.0688
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0525 0.2402 0.5582
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Brugia malayi Inositol-1 0.011 0.0413 0.1632
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0031 0.0039 0.0065
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0123 0.0478 0.111
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0123 0.0486
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0163 0.0809
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0031 0.0039 0.0191
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0045 0.0353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0119 0.046 0.1068
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.2044
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0413 0.172
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.081 0.081
Echinococcus multilocularis GPCR, family 2 0.0157 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Plasmodium vivax unspecified product 0.0031 0.0039 0.0191
Mycobacterium ulcerans hypothetical protein 0.0291 0.128 0.2005
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Brugia malayi larval opioid receptor 0.0049 0.0123 0.0486
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Onchocerca volvulus 0.0096 0.0347 0.1488
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0031 0.0039 0.0161
Mycobacterium leprae Probable lipase LipE 0.0291 0.128 1
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.128 0.5021
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0358 0.1349
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Echinococcus granulosus cathepsin L 0.0031 0.0039 0.0039
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0045 0.0224
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0143 0.0143
Plasmodium falciparum serine repeat antigen 7 0.0031 0.0039 0.0191
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Loa Loa (eye worm) hypothetical protein 0.0339 0.1512 0.3514
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0685
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0026 0.0026
Trichomonas vaginalis immunophilin, putative 0.0446 0.2021 0.8414
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0503 0.1926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0347 0.1369
Echinococcus granulosus lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Plasmodium vivax unspecified product 0.0058 0.0168 0.0831
Loa Loa (eye worm) hypothetical protein 0.0248 0.1076 0.25
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus cysteine protease 0.0058 0.0168 0.0168
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0061 0.0183 0.1427
Brugia malayi Ets-domain containing protein 0.0077 0.026 0.1026
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0268 0.1117
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis beta LACTamase domain containing family member 0.0291 0.128 0.128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0031 0.0039 0.0161
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0123 0.0123
Trypanosoma cruzi importin beta-1 subunit, putative 0.007 0.0225 0.082
Loa Loa (eye worm) hypothetical protein 0.0167 0.0688 0.16
Loa Loa (eye worm) fli-1 protein 0.0235 0.1014 0.2356
Echinococcus granulosus beta LACTamase domain containing family member 0.0291 0.128 0.128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0016 0.0121
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0163 0.0646
Echinococcus granulosus Chromobox protein 3 0.0023 0.000000012859 0.000000012859
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0123 0.0123
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.037 0.037
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.02 0.156
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0052 0.0405
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0123 0.0286
Brugia malayi PHD-finger family protein 0.0029 0.0026 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.006 0.006
Schistosoma mansoni immunophilin 0.0384 0.1728 0.1728
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Toxoplasma gondii exonuclease III APE 0.0057 0.0163 0.1277
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0123 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0158 0.0656
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0138 0.032
Schistosoma mansoni hypothetical protein 0.2059 0.9734 0.9734
Echinococcus granulosus inositol monophosphatase 1 0.011 0.0413 0.0413
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0061 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0051 0.0133 0.0309
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0163 0.0808
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0091 0.0324 0.0752
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.006
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.026 0.0604
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0192 0.081 0.3148
Brugia malayi chromobox protein homolog 3 0.0079 0.0268 0.106
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0696
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0031 0.0039 0.0191
Echinococcus multilocularis snurportin 1 0.0923 0.4304 0.4304
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0336 0.0336
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.1273 0.63
Brugia malayi Bromodomain containing protein 0.0158 0.0647 0.2554
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0049 0.0123 0.0123
Echinococcus granulosus cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Schistosoma mansoni hypothetical protein 0.0096 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0128 0.0503 0.1168
Brugia malayi Bromodomain containing protein 0.008 0.0272 0.1073
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0297 0.1276
Echinococcus granulosus chromobox protein 1 0.0141 0.0565 0.0565
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0358 0.177
Brugia malayi Melatonin receptor type 1A 0.0049 0.0123 0.0486
Echinococcus granulosus tar DNA binding protein 0.0063 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0058 0.0164 0.0164
Onchocerca volvulus Alhambra homolog 0.0029 0.0026 0.0111
Echinococcus granulosus cathepsin L cysteine proteinase 0.0098 0.0358 0.0358
Entamoeba histolytica myo-inositol monophosphatase, putative 0.011 0.0413 0.2044
Brugia malayi Serotonin receptor 0.0049 0.0123 0.0486
Onchocerca volvulus 0.0104 0.0387 0.1662
Brugia malayi 6-phosphofructokinase 0.0121 0.0466 0.1842
Brugia malayi SET domain containing protein 0.0026 0.0015 0.0058
Trypanosoma cruzi cysteine proteinase, putative 0.0058 0.0168 0.0594
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Plasmodium falciparum importin beta, putative 0.0086 0.0303 0.1498
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.046 0.1754
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0446 0.2021 0.3165
Leishmania major peptidylprolyl isomerase-like protein 0.0446 0.2021 1
Schistosoma mansoni fk506 binding protein 0.0061 0.0183 0.0183
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0031 0.0039 0.0191
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0093 0.0332 0.0332
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0061 0.0183 0.0904
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.128 0.128
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0026 0.0016 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0923 0.4304 1
Echinococcus granulosus neuropeptide receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) MBCTL1 0.0167 0.0688 0.1598
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0031 0.0039 0.0191
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0058 0.0168 0.0168
Trypanosoma brucei PAB1-binding protein , putative 0.0128 0.0503 0.2486
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0297 0.1236
Echinococcus granulosus survival motor neuron protein 1 0.0469 0.2131 0.2131
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0042 0.009 0.0389
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Leishmania major hypothetical protein, conserved 0.0034 0.0052 0.0256
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0446 0.2021 0.4697
Echinococcus granulosus allatostatin A receptor 0.0049 0.0123 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0031 0.0039 0.009
Trichomonas vaginalis esterase, putative 0.0291 0.128 0.533
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0016 0.0067
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0098 0.0358 0.2798
Giardia lamblia Hypothetical protein 0.0061 0.0183 0.0787
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0358 0.1536
Trichomonas vaginalis fk506 binding protein, putative 0.0061 0.0183 0.0761
Echinococcus granulosus cathepsin l1 0.0071 0.0228 0.0228
Onchocerca volvulus 0.0049 0.0123 0.0528
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0123 0.0486
Echinococcus multilocularis neuropeptide receptor A26 0.1893 0.8942 0.8942
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0356 0.1759
Loa Loa (eye worm) carbonic anhydrase 3 0.0119 0.046 0.1068
Brugia malayi Latrophilin receptor protein 2 0.0157 0.0641 0.253
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Schistosoma mansoni chromobox protein 0.0141 0.0565 0.0565
Echinococcus multilocularis fk506 binding protein 0.0446 0.2021 0.2021
Schistosoma mansoni hypothetical protein 0.0043 0.0095 0.0095
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0123 0.0486
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0058 0.0168 0.0594
Echinococcus granulosus snurportin 1 0.0923 0.4304 0.4304
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0039 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0429 0.1634
Mycobacterium tuberculosis Conserved protein 0.0291 0.128 0.1459
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0031 0.0039 0.0191
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis cysteine protease 0.0098 0.0358 0.0358
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0123 0.0486
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0157 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.011 0.0415 0.0963
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus granulosus dnaJ subfamily B 0.0412 0.1858 0.1858
Echinococcus multilocularis zinc finger protein 0.0043 0.0093 0.0093
Echinococcus multilocularis Tolloid protein 1 0.0026 0.0016 0.0016
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0446 0.2021 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1663 0.7842 0.7842
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0178 0.074 0.074
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis lysosomal alpha glucosidase 0.0509 0.2323 0.2323
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0031 0.0039 0.0191
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0168 0.0831
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0123 0.0123
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0098 0.0358 0.177
Trypanosoma brucei hypothetical protein, conserved 0.0061 0.0183 0.0904
Trichomonas vaginalis maltase-glucoamylase, putative 0.0113 0.0429 0.1787
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0061 0.0183 0.0722
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 0.797
Echinococcus multilocularis peregrin 0.0033 0.0049 0.0049
Brugia malayi Cytochrome P450 family protein 0.0052 0.0138 0.0544
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0123 0.0286
Echinococcus granulosus histone acetyltransferase MYST2 0.0167 0.0688 0.0688
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Plasmodium vivax vivapain-1 0.0058 0.0168 0.0831
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0 0.0001
Schistosoma mansoni Mername-AA248 (C02 family) 0.0063 0.0191 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.009 0.0357
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0192 0.081 0.4005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.009 0.0286
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0028 0.0028
Schistosoma mansoni cathepsin B (C01 family) 0.0031 0.0039 0.0039
Toxoplasma gondii cathepsin CPL 0.0098 0.0358 0.2794
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Loa Loa (eye worm) calpain 5 0.0044 0.01 0.0233
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0413 0.172
Brugia malayi jmjC domain containing protein 0.0093 0.0336 0.1327
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0356 0.1405
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.006 0.006
Trypanosoma cruzi major cysteine proteinase, putative 0.0078 0.0261 0.0963
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0079 0.0327
Loa Loa (eye worm) hypothetical protein 0.0066 0.0206 0.0479
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0052 0.0132
Echinococcus multilocularis Chromobox protein 3 0.0023 0.000000012859 0.000000012859
Plasmodium vivax vivapain-2 0.0098 0.0358 0.177
Toxoplasma gondii cathepsin CPC1 0.0031 0.0039 0.0302
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Leishmania major hypothetical protein, conserved 0.0291 0.128 0.6334
Brugia malayi jmjC domain containing protein 0.004 0.0082 0.0325
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0183 0.0761
Echinococcus multilocularis SAM and MBT domain containing protein 0.0147 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus granulosus importin subunit beta 1 0.0086 0.0303 0.0303
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Echinococcus granulosus polycomb protein SCMH1 0.0147 0.0591 0.0591
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0079 0.0264
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0058 0.0164 0.0164
Mycobacterium tuberculosis Probable lipase LipD 0.0291 0.128 0.1459
Onchocerca volvulus 0.003 0.0034 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0168 0.0831
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0163 0.0808
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0363 0.0363
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0466 0.1084
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0163 0.3954
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Entamoeba histolytica cysteine protease, putative 0.0031 0.0039 0.0191
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0291 0.128 0.5498
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0026 0.0016 0.0016
Brugia malayi cathepsin F-like cysteine proteinase 0.0031 0.0039 0.0153
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Ets-domain containing protein 0.0077 0.026 0.1026
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0089 0.0208
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Onchocerca volvulus 0.0098 0.0358 0.1536
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0358 0.0831
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Brugia malayi hypothetical protein 0.0469 0.2131 0.8416
Brugia malayi hypothetical protein 0.0083 0.0285 0.1127
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0163 0.0576
Brugia malayi Pre-SET motif family protein 0.0448 0.2033 0.8031
Brugia malayi Cathepsin L-like precursor 0.0098 0.0358 0.1413
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Brugia malayi MAP kinase sur-1 0.0157 0.0642 0.2538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0446 0.2021 0.7985
Schistosoma mansoni inositol monophosphatase 0.011 0.0413 0.0413
Trypanosoma brucei importin beta-1 subunit, putative 0.0086 0.0303 0.1498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Schistosoma mansoni hypothetical protein 0.0339 0.1512 0.1512
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0036
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni hypothetical protein 0.0093 0.0332 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Echinococcus granulosus peregrin 0.0033 0.0049 0.0049
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 1
Trypanosoma cruzi ISWI complex protein 0.0032 0.0042 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0446 0.2021 0.797
Echinococcus granulosus fmrfamide receptor 0.0049 0.0123 0.0123
Echinococcus granulosus calpain 5 0.0063 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Brugia malayi Augmenter of liver regeneration 0.0034 0.0052 0.0205
Trypanosoma brucei calpain-like protein, putative 0.0063 0.0191 0.0943
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0004 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0144 0.058 0.2233
Loa Loa (eye worm) hypothetical protein 0.0051 0.0134 0.0312
Loa Loa (eye worm) hypothetical protein 0.0093 0.0332 0.0771
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0591 0.0591
Plasmodium vivax vivapain-2 0.0098 0.0358 0.177
Brugia malayi calpain 7 0.0063 0.0191 0.0754
Trypanosoma cruzi cruzipain precursor, putative 0.0144 0.058 0.2233
Entamoeba histolytica cysteine proteinase 1, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0943
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0 0.0001
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0016 0.0061
Schistosoma mansoni hypothetical protein 0.0029 0.0026 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0123 0.0123
Schistosoma mansoni calpain-7 (C02 family) 0.0066 0.0206 0.0206
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0123 0.0123
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0123 0.0123
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Onchocerca volvulus 0.0049 0.0123 0.0528
Schistosoma mansoni alpha glucosidase 0.0113 0.0429 0.0429
Brugia malayi sulfakinin receptor protein 0.0049 0.0123 0.0486
Schistosoma mansoni cpg binding protein 0.0038 0.0071 0.0071
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0358 0.1536
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0556 0.0556
Trypanosoma cruzi ISWI complex protein 0.0032 0.0042 0.0093
Loa Loa (eye worm) hypothetical protein 0.0061 0.0183 0.0425
Trypanosoma brucei ISWI complex protein 0.0032 0.0042 0.0207
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0028 0.0065
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0045 0.0224
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0842
Schistosoma mansoni hypothetical protein 0.2059 0.9734 0.9734
Echinococcus multilocularis 0.0061 0.0183 0.0183
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0466 0.1084
Plasmodium falciparum cysteine proteinase falcipain 1 0.0058 0.0168 0.0831
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0123 0.0123
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.02 0.02
Trypanosoma brucei carbonic anhydrase-like protein 0.0119 0.046 0.2273
Loa Loa (eye worm) hypothetical protein 0.0291 0.128 0.2975
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0466 0.1941
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0157 0.0642 0.1493
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Echinococcus multilocularis musashi 0.011 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0552 0.2532 0.2532
Echinococcus multilocularis cpg binding protein 0.0038 0.0071 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.009 0.0377
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0283 0.0283
Brugia malayi Calcitonin receptor-like protein seb-1 0.0496 0.2263 0.894
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0054 0.0054
Echinococcus multilocularis somatostatin receptor 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) beta-lactamase 0.0291 0.128 0.2975
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0064 0.0194 0.0194
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0061 0.0183 0.0208
Onchocerca volvulus Huntingtin homolog 0.0248 0.1076 0.462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis polycomb protein SCMH1 0.0147 0.0591 0.0591
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0042 0.009 0.021
Echinococcus multilocularis laminin 0.0026 0.0016 0.0016
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0466 0.0466
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0043 0.01
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0163 0.0163
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0061 0.0183 0.0183
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0052 0.0256
Echinococcus granulosus lamin dm0 0.011 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0415 0.0963
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0016 0.0121
Echinococcus multilocularis expressed conserved protein 0.0092 0.0327 0.0327
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0061 0.0183 0.0425
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0016 0.0061
Plasmodium vivax calpain, putative 0.0063 0.0191 0.0944
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0446 0.2021 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0556 0.0556
Brugia malayi G-protein coupled receptor 0.0049 0.0123 0.0486
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0034 0.0145
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.0565 0.1313
Echinococcus granulosus GTP binding nuclear protein Ran 0.0064 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0248 0.1076 0.25
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0463 0.2105 0.2105
Plasmodium vivax serine-repeat antigen (SERA) 0.0031 0.0039 0.0191
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus jumonji domain containing protein 0.004 0.0079 0.0079
Loa Loa (eye worm) intermediate filament protein 0.011 0.0415 0.0963
Mycobacterium tuberculosis Probable esterase LipL 0.0291 0.128 0.1459
Echinococcus granulosus chromobox protein 1 0.0141 0.0565 0.0565
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0168 0.0594
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0123 0.0123
Schistosoma mansoni calpain-7 (C02 family) 0.0066 0.0206 0.0206
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0446 0.2021 1
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0045 0.2472
Schistosoma mansoni aldehyde dehydrogenase 0.0182 0.0761 0.0761
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0089 0.0089
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0079 0.0388
Schistosoma mansoni carbonic anhydrase-related 0.0027 0.0019 0.0019
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0052 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0 0.0001
Brugia malayi mbt repeat family protein 0.0147 0.0591 0.2333
Brugia malayi hypothetical protein 0.0248 0.1076 0.425
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0589 0.2708 0.2708
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0098 0.0358 0.177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.0039 0.0161
Schistosoma mansoni lamin 0.011 0.0415 0.0415
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0031 0.0039 0.0039
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Loa Loa (eye worm) calpain 0.0063 0.0191 0.0443
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0052 0.0405
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.009 0.0286
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0093 0.0332 0.1311
Plasmodium vivax importin-beta 2, putative 0.0086 0.0303 0.1498
Echinococcus granulosus geminin 0.2059 0.9734 0.9734
Trypanosoma brucei glucosidase, putative 0.0113 0.0429 0.2124
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0466 0.3642
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.046 0.1754
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0045 0.2472
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis calpain 5 0.0063 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi latrophilin 2 splice variant baaae 0.0339 0.1512 0.5973
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0167 0.0688 0.2716
Schistosoma mansoni zinc finger protein 0.0043 0.0093 0.0093
Trypanosoma brucei cysteine peptidase C (CPC) 0.0192 0.081 0.4005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.0039 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Brugia malayi Dopamine receptor 0.0049 0.0123 0.0486
Echinococcus multilocularis survival motor neuron protein 1 0.0469 0.2131 0.2131
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.0039 0.0153
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0079 0.0079
Loa Loa (eye worm) inositol-1 0.011 0.0413 0.096
Loa Loa (eye worm) RNA binding protein 0.0063 0.0188 0.0438
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Onchocerca volvulus Arrow homolog 0.0026 0.0016 0.0067
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.009 0.0377
Echinococcus multilocularis cathepsin b 0.0552 0.2532 0.2532
Echinococcus multilocularis serotonin receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0113 0.0429 0.1787
Echinococcus granulosus g protein coupled receptor 0.0049 0.0123 0.0123
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0123 0.0123
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0182 0.0761 0.3765
Schistosoma mansoni biogenic amine receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0291 0.128 0.1459
Trichomonas vaginalis alpha-glucosidase, putative 0.0113 0.0429 0.1787
Onchocerca volvulus 0.0062 0.0186 0.08
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0182 0.0761 0.0867
Brugia malayi G protein-coupled receptor 0.0049 0.0123 0.0486
Trypanosoma brucei hypothetical protein, conserved 0.0291 0.128 0.6334
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0045 0.0188
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0163 0.0256
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0095 0.0221
Echinococcus multilocularis neutral alpha glucosidase AB 0.0113 0.0429 0.0429
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0061 0.0183 0.0653
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0157 0.0642 0.5017
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0123 0.0123
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0123 0.0486
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0045 0.0353
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0188 0.0438
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0117 0.045 0.1718
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0496 0.2263 0.894
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0642 0.2674
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0157 0.0642 0.3178
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.046 0.046
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0163 0.0186
Brugia malayi Cathepsin L-like precursor 0.0027 0.0019 0.0074
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus multilocularis geminin 0.2059 0.9734 0.9734
Trichomonas vaginalis sucrase-isomaltase, putative 0.0113 0.0429 0.1787
Schistosoma mansoni bromodomain containing protein 0.0134 0.053 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0228 0.0951
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0064 0.0194 0.0958
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.128 0.533
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0183 0.0761
Giardia lamblia Cysteine protease 0.0031 0.0039 0.0065
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0503 0.1926
Brugia malayi beta-lactamase 0.0291 0.128 0.5058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0168 0.0699
Echinococcus granulosus neuropeptide s receptor 0.1893 0.8942 0.8942
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0167 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0071 0.0228 0.0531
Brugia malayi PHD-finger family protein 0.0054 0.0147 0.058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0064 0.0194 0.0765
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.128 0.128
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0429 0.1634
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0463 0.2105 0.2105
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0045 0.0224
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0031 0.0039 0.0191
Onchocerca volvulus 0.0071 0.0228 0.0981
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0052 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0061 0.0183 0.4421
Onchocerca volvulus 0.0291 0.128 0.5498
Toxoplasma gondii LsmAD domain-containing protein 0.0128 0.0503 0.3925
Brugia malayi RNA, U transporter 1 0.0246 0.1065 0.4208
Schistosoma mansoni amine GPCR 0.0049 0.0123 0.0123
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0183 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0268 0.1117
Schistosoma mansoni survival motor neuron protein 0.0096 0.0347 0.0347
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0171 0.0397
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0565 0.0644
Brugia malayi hypothetical protein 0.0128 0.0503 0.1985
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0052 0.0256
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0004 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0358 0.1489
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0052 0.0132
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0004 0.0021
Echinococcus multilocularis carbonic anhydrase 0.0027 0.0019 0.0019
Echinococcus granulosus calpain A 0.0063 0.0191 0.0191
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0079 0.0079
Echinococcus granulosus mitogen activated protein kinase 3 0.0157 0.0642 0.0642
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0123 0.0123
Brugia malayi phosphofructokinase 0.0121 0.0466 0.1842
Toxoplasma gondii HEAT repeat-containing protein 0.0086 0.0303 0.2366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0123 0.0123
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.0168 0.0664
Onchocerca volvulus 0.0049 0.0123 0.0528
Loa Loa (eye worm) hypothetical protein 0.0148 0.0598 0.1389
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0123 0.0486
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0589 0.2708 0.2708
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0123 0.0123
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0147 0.0591 0.2536
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Trypanosoma cruzi cysteine proteinase, putative 0.0058 0.0168 0.0594
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.006 0.006
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0384 0.1728 0.1728
Echinococcus granulosus SAM and MBT domain containing protein 0.0147 0.0591 0.0591
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0123 0.0123
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0082 0.0082
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0182 0.0761 0.0761
Echinococcus multilocularis inositol monophosphatase 1 0.011 0.0413 0.0413
Leishmania major glycosyl hydrolase-like protein 0.0042 0.009 0.0447
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0363 0.1627 0.6773
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0123 0.0486
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0283 0.1118
Schistosoma mansoni hypothetical protein 0.0903 0.4207 0.4207
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0188 0.0188
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0163 0.038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0291 0.128 0.1459
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0051 0.0133 0.0309
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0466 0.0531
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0019 0.0074
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0163 0.068
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0388
Echinococcus granulosus caspase 2 0.003 0.0034 0.0034
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0244 0.0244
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0123 0.0286
Loa Loa (eye worm) ctsf protein 0.0098 0.0358 0.0831
Echinococcus multilocularis microtubule associated protein 2 0.2114 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0157 0.0642 0.2482
Onchocerca volvulus Deterin homolog 0.0093 0.0332 0.1425
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.1273 0.63
Echinococcus granulosus intermediate filament protein 0.011 0.0415 0.0415
Plasmodium falciparum serine repeat antigen 3 0.0031 0.0039 0.0191
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0188 0.0744
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Schistosoma mansoni opsin-like receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.128 0.533
Echinococcus multilocularis calpain family protein 1, d 0.0123 0.0478 0.0478
Brugia malayi neuropeptide F receptor 0.0049 0.0123 0.0486
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0123 0.0123
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0028 0.0028
Toxoplasma gondii preprocathepsin c precursor, putative 0.0031 0.0039 0.0302
Schistosoma mansoni neuropeptide receptor 0.0049 0.0123 0.0123
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0089 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Schistosoma mansoni myelin transcription factor 1 myt1 0.0167 0.0688 0.0688
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0027 0.0019 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0031 0.0039 0.0161
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0031 0.0039 0.0191
Brugia malayi hypothetical protein 0.0148 0.0596 0.2353
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0297 0.1236
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0123 0.0123
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0119 0.046 0.1815
Brugia malayi TAR-binding protein 0.0063 0.0188 0.0744
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Loa Loa (eye worm) hypothetical protein 0.0108 0.0405 0.0941
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0358 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0248 0.0248
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0358 0.0358
Mycobacterium tuberculosis Probable lipase LipE 0.0291 0.128 0.1459
Schistosoma mansoni ap endonuclease 0.0057 0.0163 0.0163
Onchocerca volvulus 0.0093 0.0332 0.1425
Echinococcus multilocularis calpain A 0.0178 0.074 0.074
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0123 0.0123
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Echinococcus granulosus laminin 0.0026 0.0016 0.0016
Loa Loa (eye worm) fibroinase 0.0098 0.0358 0.0831
Plasmodium falciparum serine repeat antigen 1 0.0031 0.0039 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0525 0.2402 1
Brugia malayi Fli-1 protein 0.0235 0.1014 0.4005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0031 0.0039 0.009
Echinococcus multilocularis cathepsin L 0.0058 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0412 0.1858 0.1858
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0216 0.1683
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0157 0.0641 0.0641
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0509 0.2323 0.5397
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0147 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Echinococcus granulosus cathepsin L 0.0058 0.0168 0.0168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Entamoeba histolytica hypothetical protein 0.0111 0.0422 0.2086
Echinococcus granulosus cathepsin l1 0.0098 0.0358 0.0358
Trichomonas vaginalis glucosylceramidase, putative 0.0345 0.1538 0.6403
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0079 0.031
Echinococcus granulosus somatostatin receptor 0.0049 0.0123 0.0123
Brugia malayi Dopamine receptor protein 1 0.0049 0.0123 0.0486
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0064 0.0194 0.1513
Loa Loa (eye worm) hypothetical protein 0.0062 0.0186 0.0433
Loa Loa (eye worm) hypothetical protein 0.0089 0.0313 0.0728
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0123 0.0123
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0413 0.157
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0168 0.0831
Loa Loa (eye worm) cathepsin B 0.0192 0.081 0.1881
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0061 0.0183 0.1427
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus granulosus mitogen activated protein kinase 0.0157 0.0642 0.0642
Schistosoma mansoni calpain (C02 family) 0.0063 0.0191 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0089 0.0372
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0061 0.0183 0.0425
Giardia lamblia Hypothetical protein 0.0031 0.0039 0.0065
Echinococcus granulosus FK506 binding protein 2 0.0061 0.0183 0.0183
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0027 0.0019 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0031 0.0039 0.0166
Schistosoma mansoni gabp alpha 0.0077 0.026 0.026
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0031 0.0039 0.0039
Leishmania major importin beta-1 subunit, putative 0.007 0.0225 0.1111
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.006 0.006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0536 0.2453 0.5699
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Trichomonas vaginalis inositol monophosphatase, putative 0.011 0.0413 0.172
Onchocerca volvulus 0.0049 0.0123 0.0528
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0958
Echinococcus multilocularis protein dispatched 1 0.0048 0.0118 0.0118
Plasmodium vivax ataxin-2 like protein, putative 0.0128 0.0503 0.2487
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0 0.0001
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0466 0.2307
Trypanosoma brucei importin beta-1 subunit, putative 0.0086 0.0303 0.1498
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0123 0.0123
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0466 0.0466
Schistosoma mansoni inositol monophosphatase 0.011 0.0413 0.0413
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0123 0.0123
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0528 0.1228
Brugia malayi cathepsin B-like cysteine proteinase 0.0552 0.2532 1
Onchocerca volvulus 0.0032 0.0043 0.0185
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0027 0.0019 0.0076
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0178 0.074 0.074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1858 0.8777 1
Trypanosoma brucei kinesin, putative 0.0044 0.01 0.0495
Loa Loa (eye worm) hypothetical protein 0.0148 0.0595 0.1383
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Brugia malayi hypothetical protein 0.0049 0.0123 0.0486
Trichomonas vaginalis Importin beta-1 subunit, putative 0.007 0.0225 0.0935
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0336 0.0336
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0283 0.0283
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0466 0.1084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0123 0.0123
Echinococcus granulosus calpain 0.0063 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0086 0.0303 0.0704
Giardia lamblia Cathepsin B precursor 0.0031 0.0039 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0463 0.2105 0.2105
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0113 0.0429 0.2124
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0061 0.0183 0.0722
Plasmodium vivax hypothetical protein, conserved 0.0291 0.128 0.6334
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0026 0.0026
Leishmania major alpha glucosidase II subunit, putative 0.0113 0.0429 0.2124
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0356 0.0356
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0061 0.0183 0.0425
Onchocerca volvulus 0.0098 0.0358 0.1536
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.1273 0.5301
Brugia malayi Bromodomain containing protein 0.0033 0.0049 0.0195
Brugia malayi calpain 5 0.0044 0.01 0.0396
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.009 0.0377
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.1273 0.63
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0004 0.0017
Brugia malayi MH2 domain containing protein 0.0134 0.0528 0.2088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0045
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0183 0.0904
Echinococcus granulosus carbonic anhydrase 0.0027 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0167 0.0688 0.1598
Leishmania major cathepsin L-like protease 0.0098 0.0358 0.1769
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0078
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0565 0.0885
Plasmodium falciparum serine repeat antigen 5 0.0031 0.0039 0.0191
Onchocerca volvulus 0.0148 0.0596 0.2559
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0035 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0031 0.0039 0.0039
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0171 0.0397
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0185 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0363 0.1627 0.6773
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0031 0.0039 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0144 0.058 0.2868
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.037 0.037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0123 0.0123
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0147 0.0591 0.1372
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.009
Trichomonas vaginalis importin beta-1, putative 0.007 0.0225 0.0935
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0093 0.0332 0.0332
Schistosoma mansoni cathepsin s 0.0027 0.0019 0.0019
Onchocerca volvulus Cathepsin L homolog 0.0031 0.0039 0.0166
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0466 0.2307
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Echinococcus multilocularis protein patched 0.0042 0.0089 0.0089
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0082 0.0082
Brugia malayi CHD4 protein 0.0029 0.0028 0.011
Loa Loa (eye worm) FKBP5 protein 0.0446 0.2021 0.4697
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0552 0.2532 0.2532
Brugia malayi Glycosyl hydrolases family 31 protein 0.0509 0.2323 0.9176
Onchocerca volvulus 0.0049 0.0123 0.0528
Echinococcus multilocularis importin subunit beta 1 0.0086 0.0303 0.0303
Trypanosoma brucei glycosyl hydrolase-like protein 0.0042 0.009 0.0447
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0163 0.0809
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0063 0.0191 0.0943
Echinococcus multilocularis lamin 0.011 0.0415 0.0415
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0123 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0019 0.0078
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0291 0.128 0.2005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0123 0.0123
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0031 0.0039 0.0191
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0045 0.0223
Schistosoma mansoni ets-related 0.0235 0.1014 0.1014
Plasmodium falciparum serine repeat antigen 2 0.0031 0.0039 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0168 0.0699
Entamoeba histolytica calpain large subunit domain III containing protein 0.0044 0.01 0.0496
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0052 0.0132
Brugia malayi cathepsin L-like precursor 0.0071 0.0228 0.0902
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0063 0.0191 0.0685
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0565 0.2353
Echinococcus multilocularis hypothetical protein 0.0063 0.0191 0.0191
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0183 0.0761
Echinococcus multilocularis calpain 0.0063 0.0191 0.0191
Echinococcus multilocularis sex peptide receptor 0.0049 0.0123 0.0123
Echinococcus multilocularis inhibitor of apoptosis protein 0.0093 0.0332 0.0332
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0082 0.0082
Echinococcus multilocularis cathepsin L 0.0031 0.0039 0.0039
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0123 0.0123
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0061 0.0183 0.0904
Leishmania major hypothetical protein, conserved 0.0128 0.0503 0.2486
Giardia lamblia Cathepsin L precursor 0.0031 0.0039 0.0065
Loa Loa (eye worm) hypothetical protein 0.0157 0.0641 0.1488
Loa Loa (eye worm) hypothetical protein 0.0082 0.0283 0.0658
Entamoeba histolytica cysteine protease, putative 0.0058 0.0168 0.0831
Giardia lamblia Cathepsin L-like protease 0.0031 0.0039 0.0065
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0031 0.0039 0.0191
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0157 0.0641 0.253
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0079 0.0238
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0466 0.2307
Onchocerca volvulus 0.0147 0.0591 0.2536
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0123 0.0123
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0422 0.0422
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0283 0.0283
Onchocerca volvulus 0.0082 0.0283 0.1216
Plasmodium falciparum phd finger protein, putative 0.0029 0.0026 0.0127
Leishmania major carbonic anhydrase-like protein 0.0119 0.046 0.2273
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.026 0.026
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0082 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0358 0.1489
Schistosoma mansoni hypothetical protein 0.0027 0.0019 0.0019
Onchocerca volvulus 0.0049 0.0123 0.0528
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0565 0.4416
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0031 0.0039 0.0191
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0064 0.0194 0.0696
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0082
Leishmania major cysteine peptidase A (CPA) 0.0098 0.0358 0.1769
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0035 0.0145
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0026 0.0016 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0123 0.0286

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 2.45 uM/L Growth inhibition of human Ishikawa cells ChEMBL. 19515562
IC50 (functional) = 75.18 uM/L Growth inhibition of human A549 cells ChEMBL. 19515562

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 19515562

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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