Detailed information for compound 1158188

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 350.366 | Formula: C17H22N2O6
  • H donors: 5 H acceptors: 4 LogP: 0.53 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN[C@@H]1C[C@@H]2[C@H]([C@@H]([C@@H]1O)O)NC(=O)c1c2cc2OCOc2c1O
  • InChi: 1S/C17H22N2O6/c1-2-3-18-9-4-8-7-5-10-16(25-6-24-10)14(21)11(7)17(23)19-12(8)15(22)13(9)20/h5,8-9,12-13,15,18,20-22H,2-4,6H2,1H3,(H,19,23)/t8-,9+,12+,13+,15-/m0/s1
  • InChiKey: KLOYXGIFOGMZNV-KLDWPMRUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0111
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0087 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.0397 0.1399
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0003
Plasmodium falciparum histone acetyltransferase GCN5 0.0063 0.0094 0.2459
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0213 0.0397 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0001
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.0032 0.009
Toxoplasma gondii hypothetical protein 0.004 0.0047 0.0153
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0054 0.0077 0.023
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0036 0.0039 0.0228
Brugia malayi conserved hypotetical protein 0.0029 0.0024 0.0066
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0081
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0024 0.0066
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0032 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-14 0.006 0.0089 0.0271
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.0043 0.0123
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0128 0.0225 0.5607
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.009
Mycobacterium tuberculosis Probable lipase LipD 0.0061 0.009 0.1143
Toxoplasma gondii thioredoxin reductase 0.0033 0.0034 0.0105
Echinococcus multilocularis beta LACTamase domain containing family member 0.0061 0.009 0.0086
Plasmodium falciparum DNA topoisomerase 2 0.0088 0.0144 0.386
Schistosoma mansoni glycogen phosphorylase 0.0037 0.0042 0.0116
Echinococcus multilocularis caspase 8 0.0062 0.0092 0.0088
Echinococcus granulosus snurportin 1 0.0478 0.0933 0.2602
Trypanosoma cruzi metacaspase, putative 0.0062 0.0092 0.0278
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0024 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus granulosus lamin 0.007 0.0109 0.0292
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0076 0.012 0.1541
Giardia lamblia Histone acetyltransferase GCN5 0.0063 0.0094 0.2459
Echinococcus multilocularis cathepsin L cysteine protease 0.0031 0.003 0.0026
Trypanosoma cruzi metacaspase 5, putative 0.0062 0.0092 0.0278
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Entamoeba histolytica protein kinase rad3, putative 0.0054 0.0077 0.0258
Schistosoma mansoni tar DNA-binding protein 0.0382 0.0739 0.2067
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0128 0.0225 0.0781
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0036 0.0039 0.0109
Trichomonas vaginalis heat shock protein, putative 0.0088 0.0144 0.0499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Schistosoma mansoni fkbp-rapamycin associated protein 0.0054 0.0077 0.0215
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0035 0.0037 0.0103
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0552 0.1082 0.3419
Toxoplasma gondii target of rapamycin (TOR), putative 0.0096 0.0162 0.0561
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0088 0.0144 0.3565
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0077 0.0232
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0179
Brugia malayi hypothetical protein 0.0032 0.0032 0.009
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0076 0.012 0.1541
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0005 0.0005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0158 0.043
Schistosoma mansoni nuclear receptor 0.0029 0.0024 0.0068
Schistosoma mansoni alpha-glucosidase 0.0111 0.0192 0.0536
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0005 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.006 0.0089 0.109
Schistosoma mansoni zinc finger protein 0.0029 0.0024 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.009 0.0271
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0245 0.0461 0.5888
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0119 0.0207 0.2703
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Echinococcus granulosus geminin 0.0715 0.1411 0.3939
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0119 0.0332
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0034 0.0814
Echinococcus granulosus expressed conserved protein 0.0147 0.0263 0.0725
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0005 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0005 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0232 0.0436 0.1367
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0089 0.0271
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0031 0.003 0.0082
Echinococcus granulosus importin subunit beta 1 0.0045 0.0057 0.0149
Echinococcus granulosus expressed conserved protein 0.0201 0.0373 0.1034
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0096 0.0162 0.0499
Brugia malayi hypothetical protein 0.0032 0.0031 0.0088
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0213 0.0397 0.1244
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0076
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0179
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Entamoeba histolytica hypothetical protein 0.0198 0.0367 0.1292
Echinococcus multilocularis lysosomal alpha glucosidase 0.0129 0.0228 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0089 0.0271
Leishmania major GTP-binding protein, putative 0.0033 0.0034 0.0092
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0054 0.0077 0.023
Echinococcus granulosus heat shock protein 0.0088 0.0144 0.0392
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis protein kinase inhibitor, putative 0.0063 0.0095 0.0323
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0043 0.0123
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0033 0.0034 0.0803
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0198 0.0367 0.1292
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0088 0.0144 0.1869
Trypanosoma brucei hypothetical protein, conserved 0.0061 0.009 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0382 0.0739 0.2067
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0024 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0015
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0054 0.0077 0.0258
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0084 0.0137 0.3374
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Brugia malayi kinase, mitochondrial precursor 0.1579 0.3157 1
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0088 0.0144 0.0495
Onchocerca volvulus 0.0029 0.0024 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0041 0.0114
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0088 0.0144 0.1869
Echinococcus granulosus cathepsin l1 0.0021 0.0009 0.0014
Echinococcus multilocularis caspase 0.0164 0.0298 0.0293
Onchocerca volvulus 0.0037 0.0043 0.0492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0128 0.0225 0.0698
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0092 0.0152 0.0472
Plasmodium vivax 6-phosphofructokinase, putative 0.0058 0.0083 0.2171
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0032 0.0031 0.0086
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0043 0.0123
Loa Loa (eye worm) hypothetical protein 0.0184 0.0339 0.1061
Loa Loa (eye worm) pigment dispersing factor receptor c 0.029 0.0553 0.1741
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0034 0.0035 0.0031
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0096 0.0162 0.0499
Schistosoma mansoni endoplasmin 0.0088 0.0144 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0058 0.0083 0.028
Trichomonas vaginalis receptor histidine kinase, putative 0.0088 0.0144 0.0499
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0025 0.0573
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0092 0.0152 0.0415
Trichomonas vaginalis penicillin-binding protein, putative 0.0061 0.009 0.0305
Schistosoma mansoni cathepsin F (C01 family) 0.0031 0.003 0.0085
Loa Loa (eye worm) DnaJ domain-containing protein 0.0063 0.0095 0.0287
Trypanosoma cruzi heat shock protein 90, putative 0.0088 0.0144 0.0444
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0088 0.0144 0.0444
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0019 0.0004 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0033 0.0034 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0225 0.0698
Brugia malayi hypothetical protein 0.0032 0.0032 0.009
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0062 0.0093 0.2443
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0068 0.0105 0.0359
Brugia malayi nuclear receptor NHR-88 0.006 0.0089 0.0271
Plasmodium falciparum thioredoxin reductase 0.0033 0.0034 0.0814
Plasmodium falciparum DNA gyrase subunit B 0.0088 0.0144 0.386
Leishmania major importin beta-1 subunit, putative 0.0036 0.004 0.0114
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0061 0.009 0.1143
Loa Loa (eye worm) beta-lactamase 0.0061 0.009 0.0271
Trichomonas vaginalis sensor histidine kinase, putative 0.0088 0.0144 0.0499
Entamoeba histolytica heat shock protein 90, putative 0.0088 0.0144 0.0499
Leishmania major hypothetical protein, conserved 0.0503 0.0983 0.3103
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0096 0.0162 0.0561
Schistosoma mansoni hypothetical protein 0.0092 0.0152 0.0426
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0088 0.0144 0.1869
Schistosoma mansoni retinoic acid receptor RXR 0.0194 0.0358 0.1002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0034 0.0035 0.0087
Giardia lamblia Pms1-like protein 0.0088 0.0144 0.386
Plasmodium falciparum importin beta, putative 0.0045 0.0057 0.1462
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0233 0.0437 0.1373
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0367 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0129 0.0228 0.071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.006 0.0089 0.0271
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Plasmodium vivax endoplasmin, putative 0.0088 0.0144 0.386
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0478 0.0933 0.2946
Echinococcus multilocularis cpg binding protein 0.003 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.0133 0.0236 0.0735
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0061 0.009 0.0271
Brugia malayi topoisomerase 0.0032 0.0032 0.009
Schistosoma mansoni caspase-7 (C14 family) 0.0164 0.0298 0.0833
Brugia malayi RNA recognition motif domain containing protein 0.0382 0.0739 0.2332
Echinococcus multilocularis glycogen phosphorylase 0.0085 0.014 0.0135
Mycobacterium ulcerans two component regulator - sensor kinase 0.0088 0.0144 0.0495
Brugia malayi hypothetical protein 0.0951 0.1888 0.5974
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0039 0.0124
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0063 0.0165
Brugia malayi nuclear receptor NHR-88 0.0029 0.0024 0.0066
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0096 0.0162 0.0499
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0088 0.0144 0.0446
Mycobacterium ulcerans hypothetical protein 0.0061 0.009 0.0301
Schistosoma mansoni Tr4/Tr2 (homologue) 0.006 0.0089 0.0249
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0061 0.009 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0089 0.0303
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Schistosoma mansoni RAR-like nuclear receptor 0.006 0.0089 0.0249
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0128 0.0225 0.0781
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0092 0.2416
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0052 0.0152
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0031 0.0088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0086
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Trypanosoma cruzi metacaspase, putative 0.0062 0.0092 0.0278
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0232 0.0436 0.137
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0034 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-40 0.006 0.0089 0.0271
Loa Loa (eye worm) hypothetical protein 0.0088 0.0144 0.0444
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0002
Echinococcus multilocularis synaptic glycoprotein sc2 0.0198 0.0367 0.0363
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0043 0.0132
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0025 0.0074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0084 0.0137 0.1769
Echinococcus granulosus ecdysone induced protein 78C 0.006 0.0089 0.0237
Onchocerca volvulus 0.0075 0.0118 0.1465
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0198 0.0367 0.1292
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0088 0.0144 0.3735
Brugia malayi nuclear receptor RXR 0.0032 0.0031 0.0088
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0037 0.0103
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0005 0.0001
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0005 0.0001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0218 0.0406 0.1137
Mycobacterium tuberculosis Possible two component sensor kinase 0.0088 0.0144 0.1869
Onchocerca volvulus Glycogen phosphorylase homolog 0.0085 0.014 0.1743
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0024 0.0259
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0043 0.0121
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0088 0.0144 0.0495
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0024 0.0066
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0054 0.0077 0.023
Plasmodium falciparum polyprenol reductase, putative 0.0198 0.0367 1
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.003 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0036 0.0039 0.0109
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0031 0.003 0.0026
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0058 0.0083 0.0194
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Echinococcus multilocularis protein dispatched 1 0.0105 0.0179 0.0175
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0043 0.0107
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0019 0.0004 0.0012
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0037 0.0043 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0039 0.0124
Schistosoma mansoni nuclear hormone receptor 0.006 0.0089 0.0249
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0181 0.0333 0.0329
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0015
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0181 0.0333 0.117
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0058 0.0083 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.1167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0061 0.009 0.0252
Echinococcus granulosus caspase 0.0164 0.0298 0.0822
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0025 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0089 0.0237
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0062 0.0092 0.028
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.003 0.0082
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0005 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.0436 0.1218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.0025 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Schistosoma mansoni pyruvate dehydrogenase 0.1579 0.3157 0.8833
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Trypanosoma cruzi heat shock protein 85, putative 0.0088 0.0144 0.0444
Entamoeba histolytica DNA topoisomerase II, putative 0.0088 0.0144 0.0499
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0043 0.1052
Loa Loa (eye worm) intermediate filament protein 0.007 0.0109 0.0331
Echinococcus granulosus GPCR family 2 0.0092 0.0152 0.0415
Echinococcus multilocularis caspase 3 0.0102 0.0173 0.0168
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.0032 0.0098
Entamoeba histolytica cysteine protease, putative 0.0031 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0284
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0095 0.0159 0.207
Brugia malayi cytoplasmic intermediate filament protein 0.0038 0.0043 0.0124
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0032 0.0369
Giardia lamblia Glycogen phosphorylase 0.0085 0.014 0.3728
Mycobacterium ulcerans zinc metalloprotease 0.0063 0.0094 0.0315
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0043 0.0972
Echinococcus granulosus replication factor c subunit 1 0.0032 0.0032 0.0077
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.0043 0.051
Trypanosoma cruzi Heat shock protein 83, putative 0.0088 0.0144 0.0444
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0198 0.0367 0.1292
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0121 0.0117
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0041 0.013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.1167
Trichomonas vaginalis D-aminoacylase, putative 0.0061 0.009 0.0305
Brugia malayi cathepsin L-like precursor 0.0021 0.0009 0.0018
Echinococcus multilocularis lamin 0.007 0.0109 0.0104
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0033 0.0034 0.0803
Treponema pallidum exodeoxyribonuclease (exoA) 0.0036 0.0039 0.0188
Echinococcus granulosus expressed protein 0.0369 0.0713 0.1985
Echinococcus multilocularis cysteine protease 0.0031 0.003 0.0026
Entamoeba histolytica hypothetical protein 0.0036 0.004 0.0128
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Brugia malayi Peptidase family M13 containing protein 0.0063 0.0094 0.0286
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0092 0.0312
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0119 0.0207 0.2703
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0041 0.1006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0025 0.0064
Toxoplasma gondii heat shock protein HSP90 0.0088 0.0144 0.0499
Echinococcus multilocularis Glycosyl transferase, family 35 0.0085 0.014 0.0135
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.0043 0.051
Schistosoma mansoni intermediate filament proteins 0.007 0.0109 0.0304
Leishmania major DNA polymerase eta, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0149 0.193
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0149 0.193
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0032 0.0031 0.0086
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0037 0.0042 0.0129
Mycobacterium tuberculosis Probable oxidoreductase 0.0084 0.0137 0.1769
Loa Loa (eye worm) oxidoreductase 0.0037 0.0043 0.0121
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Leishmania major DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Loa Loa (eye worm) RNA binding protein 0.0382 0.0739 0.233
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0036 0.0039 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0088 0.0144 0.1869
Trypanosoma brucei trypanothione reductase 0.0033 0.0034 0.0094
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0062 0.0093 0.2443
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0088 0.0144 0.1869
Mycobacterium tuberculosis Conserved hypothetical protein 0.013 0.0229 0.3006
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.0367 0.1292
Brugia malayi FAT domain containing protein 0.0042 0.0052 0.0153
Loa Loa (eye worm) hypothetical protein 0.0128 0.0225 0.0698
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Brugia malayi Synaptic glycoprotein SC2 0.0198 0.0367 0.1152
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0036 0.0039 0.0119
Brugia malayi RNA binding protein 0.0382 0.0739 0.2332
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0054 0.0077 0.0072
Plasmodium vivax DNA topoisomerase II, putative 0.0088 0.0144 0.386
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0088 0.0144 0.3079
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0043 0.051
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0066 0.01 0.0335
Trypanosoma brucei metacaspase 5, putative 0.0062 0.0092 0.0278
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0089 0.0237
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0015
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0066 0.01 0.0339
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0043 0.0136
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0128 0.0225 0.0781
Trypanosoma cruzi metacaspase 5, putative 0.0062 0.0092 0.0278
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Loa Loa (eye worm) hypothetical protein 0.0198 0.0367 0.115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0198 0.0367 0.115
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0445 0.1398
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0088 0.0144 0.1805
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.0972
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0088 0.0144 0.0495
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0118 0.0205 0.0574
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0025 0.0073
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0037 0.0103
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0041 0.0102
Onchocerca volvulus 0.0029 0.0025 0.0268
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0063 0.0059
Mycobacterium ulcerans hypothetical protein 0.0128 0.0225 0.0781
Mycobacterium ulcerans esterase/lipase LipP 0.0061 0.009 0.0301
Echinococcus granulosus jumonji domain containing protein 0.004 0.0048 0.0122
Loa Loa (eye worm) ctsf protein 0.0031 0.003 0.0082
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.0032 0.0761
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0096 0.0162 0.0453
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0058 0.0083 0.2171
Mycobacterium ulcerans aldehyde dehydrogenase 0.015 0.027 0.0942
Brugia malayi hypothetical protein 0.0029 0.0025 0.0068
Onchocerca volvulus Cathepsin F homolog 0.0031 0.003 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0052 0.0169
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0117 0.0203 0.0629
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.1385 0.2764 0.7731
Echinococcus granulosus caspase 8 0.0062 0.0092 0.0245
Schistosoma mansoni hypothetical protein 0.0048 0.0063 0.0177
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.0089 0.0249
Loa Loa (eye worm) phosphatidylinositol 3 0.0096 0.0162 0.0499
Brugia malayi Thioredoxin reductase 0.0033 0.0034 0.0096
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0088 0.0144 0.1869
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Toxoplasma gondii phosphofructokinase PFKII 0.0058 0.0083 0.028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus granulosus intermediate filament protein 0.007 0.0109 0.0292
Leishmania major phosphatidylinositol 3-kinase, putative 0.0096 0.0162 0.0499
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0225 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Brugia malayi CHE-14 protein 0.0092 0.0153 0.0473
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0133 0.0236 0.0649
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0029 0.0026 0.0076
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0002
Onchocerca volvulus 0.0031 0.003 0.0334
Entamoeba histolytica acetyltransferase, GNAT family 0.0063 0.0094 0.0318
Plasmodium vivax importin-beta 2, putative 0.0045 0.0057 0.1462
Loa Loa (eye worm) inositol-1 0.0066 0.01 0.0302
Schistosoma mansoni hypothetical protein 0.0092 0.0152 0.0426
Onchocerca volvulus 0.0031 0.003 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0382 0.0739 0.2067
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0088 0.0144 0.0444
Plasmodium vivax metacaspase 1, putative 0.0062 0.0092 0.2416
Brugia malayi Nuclear hormone receptor family member nhr-41 0.006 0.0089 0.0271
Brugia malayi Probable DNA topoisomerase II 0.0088 0.0144 0.0446
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.0397 0.1399
Loa Loa (eye worm) peptidase family M13 containing protein 0.0046 0.0061 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0088 0.0144 0.3565
Echinococcus multilocularis protein patched 0.0092 0.0153 0.0148
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.0032 0.0089
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Loa Loa (eye worm) hypothetical protein 0.0095 0.0159 0.0492
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0096 0.0162 0.0441
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0029 0.0026 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.006 0.0089 0.0268
Entamoeba histolytica hypothetical protein 0.0076 0.0121 0.0417
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.0436 0.1218
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0088 0.0144 0.1869
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0042 0.0052 0.0133
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0096 0.0162 0.0157
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0036 0.004 0.0128
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0088 0.0144 0.0499
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0096 0.0162 0.0499
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.0397 0.1399
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0121
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0039 0.0123
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0019 0.0004 0.0012
Brugia malayi nuclear receptor RXR 0.0029 0.0024 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0005 0.0015
Schistosoma mansoni ran 0.0033 0.0034 0.0094
Echinococcus granulosus beta LACTamase domain containing family member 0.0061 0.009 0.024
Loa Loa (eye worm) hypothetical protein 0.0951 0.1888 0.5973
Brugia malayi nuclear hormone receptor 0.0213 0.0397 0.1246
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0041 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0088 0.0144 0.3079
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0031 0.003 0.0715
Schistosoma mansoni thyroid hormone receptor 0.006 0.0089 0.0249
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0037 0.0042 0.0496
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0033 0.0034 0.0092
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0043 0.0136
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Schistosoma mansoni ap endonuclease 0.0036 0.0039 0.0109
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Onchocerca volvulus 0.0037 0.0043 0.0492
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0247 0.0465 0.1462
Schistosoma mansoni cpg binding protein 0.003 0.0028 0.0078
Onchocerca volvulus 0.0061 0.009 0.1103
Brugia malayi Probable ClpP-like protease 0.0181 0.0333 0.1044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.007 0.0109 0.0331
Plasmodium falciparum cysteine proteinase falcipain 3 0.0031 0.003 0.0715
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Echinococcus multilocularis sentrin specific protease 7 0.0161 0.0292 0.0287
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0063 0.0094 0.0262
Schistosoma mansoni cpg binding protein 0.0029 0.0025 0.0069
Schistosoma mansoni cathepsin F (C01 family) 0.0031 0.003 0.0085
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0088 0.0144 0.386
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0054 0.0077 0.0203
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0096 0.0162 0.0499
Brugia malayi nuclear hormone receptor 0.006 0.0089 0.0271
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0096 0.0162 0.0499
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0033 0.0034 0.0092
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0029 0.0026 0.0068
Brugia malayi Endoplasmin precursor 0.0088 0.0144 0.0446
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.0182 0.0563
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.0025 0.0073
Onchocerca volvulus 0.0029 0.0026 0.0275
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0043 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0088 0.0144 0.0444
Brugia malayi Inositol-1 0.0066 0.01 0.0304
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0033 0.0034 0.0803
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0058 0.0083 0.2171
Loa Loa (eye worm) 6-phosphofructokinase 0.0213 0.0397 0.1245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0036 0.0039 0.0111
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0247 0.0465 0.1462
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0113 0.0194 0.0603
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0096 0.0162 0.0499
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0088 0.0298
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.1142
Schistosoma mansoni hypothetical protein 0.0198 0.0368 0.1029
Brugia malayi phosphofructokinase 0.0213 0.0397 0.1248
Echinococcus granulosus cathepsin l1 0.0031 0.003 0.0073
Schistosoma mansoni alpha-glucosidase 0.0111 0.0192 0.0536
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Echinococcus granulosus peptidase Clp S14 family 0.0119 0.0207 0.0567
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0095 0.0159 0.0484
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0043 0.0136
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.0032 0.0761
Plasmodium falciparum heat shock protein 90 0.0088 0.0144 0.386
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0058 0.0083 0.028
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.006 0.0089 0.0249
Brugia malayi Importin beta-1 subunit 0.0045 0.0057 0.0171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0164 0.0298 0.0293
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0088 0.0144 0.0499
Schistosoma mansoni hypothetical protein 0.0063 0.0095 0.0266
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0088 0.0144 0.0499
Mycobacterium tuberculosis Probable esterase LipL 0.0061 0.009 0.1143
Trichomonas vaginalis glutaminase, putative 0.0868 0.172 0.6111
Schistosoma mansoni hypothetical protein 0.0089 0.0146 0.0408
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0233 0.0437 0.0433
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0133 0.0236 0.0661
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.1385 0.2764 0.2761
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.015 0.027 0.0842
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.0032 0.0087
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.051
Trichomonas vaginalis penicillin-binding protein, putative 0.0061 0.009 0.0305
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0031 0.003 0.0715
Brugia malayi latrophilin 2 splice variant baaae 0.0198 0.0368 0.1155
Echinococcus granulosus dna polymerase kappa 0.0019 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0198 0.0368 0.1152
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0036 0.0039 0.095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0043 0.0132
Leishmania major DNA topoisomerase ii 0.0088 0.0144 0.0444
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.006 0.0089 0.0237
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.006 0.0089 0.0237
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1408 0.2812 0.8904
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0005 0.0004
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0024 0.0068
Trypanosoma cruzi heat shock protein 85, putative 0.0088 0.0144 0.0444
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0025 0.0073
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0033 0.0034 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0089 0.0271
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0043 0.051
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0117 0.0203 0.0629
Echinococcus granulosus dnaJ subfamily B 0.0408 0.079 0.2202
Brugia malayi Cell death protein 3 precursor 0.0091 0.015 0.0465
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0066 0.01 0.0339
Entamoeba histolytica cysteine proteinase, putative 0.0021 0.0009 0.0018
Schistosoma mansoni hypothetical protein 0.0042 0.0052 0.0145
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0098
Entamoeba histolytica hypothetical protein 0.0076 0.0121 0.0417
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0284
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0005 0.0001
Toxoplasma gondii heat shock protein 90, putative 0.0088 0.0144 0.0499
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0225 0.0698
Echinococcus granulosus histone acetyltransferase KAT2B 0.0068 0.0105 0.0282
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0025 0.0073
Echinococcus granulosus lysosomal alpha glucosidase 0.0129 0.0228 0.0627
Trypanosoma brucei metacaspase 0.0062 0.0092 0.0278
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0041 0.0114
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0005
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Entamoeba histolytica glycogen phosphorylase, putative 0.0085 0.014 0.0482
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.0032 0.009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0225 0.0784
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0031 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.006 0.0089 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Chlamydia trachomatis DNA gyrase subunit B 0.0088 0.0144 0.0427
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.0032 0.0098
Brugia malayi hypothetical protein 0.0076 0.0121 0.0373
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0389 0.0753 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0092 0.0153 0.047
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0036 0.0039 0.0109
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0082
Loa Loa (eye worm) hypothetical protein 0.0095 0.0159 0.0492
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0128 0.0225 0.0781
Schistosoma mansoni alpha glucosidase 0.0029 0.0025 0.007
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0198 0.0367 0.1292
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0092 0.0152 0.0148
Schistosoma mansoni inositol monophosphatase 0.0066 0.01 0.0278
Mycobacterium leprae conserved hypothetical protein 0.0061 0.009 0.2179
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0005 0.0015
Schistosoma mansoni hypothetical protein 0.0715 0.1411 0.3946
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0043 0.0123
Plasmodium vivax acyl-CoA synthetase, putative 0.0095 0.0159 0.4275
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0032 0.0098
Entamoeba histolytica hypothetical protein 0.0054 0.0077 0.0258
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.0397 0.1399
Giardia lamblia Replication factor C, subunit 1 0.0032 0.0032 0.0761
Echinococcus granulosus survival motor neuron protein 1 0.0951 0.1888 0.5275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0194 0.0359 0.1126
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0037 0.0043 0.0132
Mycobacterium leprae Probable two-component sensor kinase 0.0088 0.0144 0.3565
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.015 0.027 0.0266
Schistosoma mansoni DNA ligase IV 0.0032 0.0032 0.0089
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.0436 0.0431
Loa Loa (eye worm) hypothetical protein 0.0095 0.0159 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.051
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0225 0.0701
Trichomonas vaginalis sucrase-isomaltase, putative 0.0029 0.0025 0.0073
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0024 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0036 0.0039 0.0109
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Leishmania major hypothetical protein, conserved 0.0061 0.009 0.0271
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0032 0.0087
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0001
Onchocerca volvulus 0.0032 0.0032 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0181 0.0333 0.8366
Echinococcus multilocularis heat shock protein 0.0088 0.0144 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0089 0.0085
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.0043 0.051
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Echinococcus multilocularis caspase 2 0.0091 0.015 0.0146
Schistosoma mansoni neprilysin-2 (M13 family) 0.0032 0.0031 0.0086
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0005 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1408 0.2812 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0039 0.095
Echinococcus multilocularis expressed conserved protein 0.0147 0.0263 0.0259
Entamoeba histolytica glycogen phosphorylase, putative 0.0037 0.0042 0.0132
Echinococcus multilocularis Niemann Pick C1 protein 0.0306 0.0585 0.0581
Echinococcus multilocularis snurportin 1 0.0478 0.0933 0.0929
Echinococcus granulosus dnaJ subfamily C 6 0.0063 0.0095 0.0254
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0069 0.0106 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0098
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0042 0.0052 0.0048
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0088 0.0144 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0043 0.0121
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0092 0.0312
Leishmania major hypothetical protein, conserved 0.0088 0.0144 0.0444
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0096 0.0162 0.0502
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0077 0.0232
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Echinococcus multilocularis muscleblind protein 0.0146 0.0261 0.0257
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.8242
Echinococcus granulosus inositol monophosphatase 1 0.0066 0.01 0.0267
Brugia malayi Steroid receptor seven-up type 2 0.006 0.0089 0.0271
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0181 0.0333 0.092
Mycobacterium ulcerans DNA gyrase subunit B 0.0088 0.0144 0.0495
Trypanosoma brucei importin beta-1 subunit, putative 0.0045 0.0057 0.0168
Giardia lamblia GTOR 0.0096 0.0162 0.434
Toxoplasma gondii FATC domain-containing protein 0.0054 0.0077 0.0258
Onchocerca volvulus Cathepsin L homolog 0.0031 0.003 0.0334
Echinococcus granulosus synaptic glycoprotein sc2 0.0198 0.0367 0.1016
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0213 0.0397 0.5244
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.0182 0.4893
Brugia malayi tailless protein 0.0029 0.0024 0.0066
Mycobacterium ulcerans two component sensor kinase MprB 0.0088 0.0144 0.0495
Brugia malayi MH2 domain containing protein 0.0237 0.0445 0.14
Brugia malayi Niemann-Pick C1 protein precursor 0.0214 0.04 0.1256
Brugia malayi steroid hormone receptor 0.006 0.0089 0.0271
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0213 0.0397 0.1245
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0161 0.0292 0.0816
Entamoeba histolytica acyl-coA synthetase, putative 0.0128 0.0225 0.0784
Schistosoma mansoni 6-phosphofructokinase 0.0213 0.0397 0.1111
Onchocerca volvulus 0.0031 0.003 0.0334
Mycobacterium tuberculosis Conserved protein 0.0061 0.009 0.1143
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Loa Loa (eye worm) glycogen phosphorylase 0.0085 0.014 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0005 0.0003
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0033 0.0034 0.0095
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0021 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0019 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0278
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.1408 0.2812 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0005 0.0015
Brugia malayi glutaminase DH11.1 0.0868 0.172 0.5442
Onchocerca volvulus 0.0029 0.0024 0.0259
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.0367 0.1292
Schistosoma mansoni hypothetical protein 0.0076 0.0121 0.0339
Echinococcus multilocularis cathepsin L cysteine protease 0.0031 0.003 0.0026
Echinococcus granulosus tar DNA binding protein 0.0382 0.0739 0.2058
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0036 0.0039 0.0123
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0076 0.012 0.1541
Schistosoma mansoni pyruvate dehydrogenase 0.1491 0.298 0.8336
Loa Loa (eye worm) hypothetical protein 0.0046 0.0061 0.0179
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0133 0.0236 0.0232
Echinococcus granulosus dna polymerase eta 0.0019 0.0005 0.0003
Brugia malayi Bromodomain containing protein 0.0035 0.0037 0.0105
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Trypanosoma cruzi heat shock protein 90, putative 0.0088 0.0144 0.0444
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0025 0.0074
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.01 0.0302
Loa Loa (eye worm) glutaminase 0.0868 0.172 0.5441
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0025 0.0021
Schistosoma mansoni cpg binding protein 0.003 0.0028 0.0078
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0025 0.0058
Toxoplasma gondii cathepsin CPL 0.0031 0.003 0.0092
Echinococcus granulosus caspase 3 0.0102 0.0173 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0402 0.078 0.246
Echinococcus granulosus microtubule associated protein 2 0.1786 0.3575 1
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0088 0.0144 0.0444
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0213 0.0397 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0041 0.013
Schistosoma mansoni endoplasmin 0.0088 0.0144 0.0404
Leishmania major metacaspase, putative 0.0062 0.0092 0.0278
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.006 0.0089 0.0085
Leishmania major trypanothione reductase 0.0033 0.0034 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0025 0.0066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0024 0.002
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.0436 0.1208
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0001
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0032 0.0087
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0025 0.0073
Onchocerca volvulus 0.0037 0.0043 0.0492
Trichomonas vaginalis heat shock protein, putative 0.0088 0.0144 0.0499
Leishmania major cysteine peptidase A (CPA) 0.0031 0.003 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0182 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0098
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0096 0.0162 0.0561
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0552 0.1082 0.3839
Loa Loa (eye worm) fibroinase 0.0031 0.003 0.0082
Echinococcus multilocularis endothelin converting enzyme 1 0.0063 0.0094 0.0089
Brugia malayi 6-phosphofructokinase 0.0213 0.0397 0.1248
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0024 0.0056
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0181 0.0333 0.9058
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.006 0.0089 0.0085
Echinococcus granulosus cathepsin L cysteine proteinase 0.0031 0.003 0.0073
Schistosoma mansoni glycogen phosphorylase 0.0085 0.014 0.0391
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0036 0.004 0.0128
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.003 0.0082
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Brugia malayi hypothetical protein 0.0019 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0041 0.013
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1408 0.2812 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0058 0.0083 0.2171
Echinococcus multilocularis importin subunit beta 1 0.0045 0.0057 0.0053
Mycobacterium tuberculosis Probable hydrolase 0.0061 0.009 0.1143
Leishmania major hypothetical protein, conserved 0.0106 0.0182 0.0563
Trypanosoma brucei Metacaspase-4 0.0062 0.0092 0.0278
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0095 0.0159 0.0548
Loa Loa (eye worm) hypothetical protein 0.0063 0.0094 0.0284
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0029 0.0026 0.0068
Echinococcus multilocularis dna polymerase eta 0.0019 0.0005 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0063 0.0094 0.1194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1408 0.2812 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0009 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0382 0.0739 0.2067
Entamoeba histolytica heat shock protein 90, putative 0.0088 0.0144 0.0499
Onchocerca volvulus 0.007 0.0109 0.1344
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0247 0.0465 0.1462
Loa Loa (eye worm) hypothetical protein 0.0106 0.0182 0.0563
Brugia malayi intermediate filament protein 0.007 0.0109 0.0333
Loa Loa (eye worm) hypothetical protein 0.0181 0.0333 0.1042
Mycobacterium ulcerans 6-phosphofructokinase 0.0213 0.0397 0.1395
Brugia malayi PHD-finger family protein 0.0029 0.0025 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.003 0.0092
Brugia malayi ecdysteroid receptor 0.006 0.0089 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0484 0.0945 0.2984
Loa Loa (eye worm) hypothetical protein 0.029 0.0553 0.1741
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Mycobacterium ulcerans aldehyde dehydrogenase 0.015 0.027 0.0942
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0068 0.0105 0.0359
Mycobacterium leprae probable zinc metalloprotease 0.0063 0.0094 0.2277
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0062 0.0092 0.0312
Echinococcus granulosus histone acetyltransferase KAT2B 0.0226 0.0424 0.1174
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0116
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0038 0.0043 0.0122
Loa Loa (eye worm) hypothetical protein 0.0091 0.015 0.0463
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0088 0.0144 0.1869
Entamoeba histolytica Ran family GTPase 0.0033 0.0034 0.0104
Echinococcus multilocularis Niemann Pick C1 protein 0.0214 0.04 0.0396
Trichomonas vaginalis receptor histidine kinase, putative 0.0088 0.0144 0.0499
Brugia malayi Nuclear hormone receptor family member nhr-1 0.006 0.0089 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0025 0.0065
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0117 0.0203 0.0629
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0043 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Brugia malayi Latrophilin receptor protein 2 0.0092 0.0152 0.0472
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0088 0.0144 0.0495
Loa Loa (eye worm) DR-78 0.0029 0.0024 0.0064
Trypanosoma cruzi metacaspase, putative 0.0062 0.0092 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.0025 0.0057
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0088 0.0144 0.0499
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0061 0.009 0.1143
Entamoeba histolytica acyl-CoA synthetase, putative 0.0128 0.0225 0.0784
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0066 0.01 0.0339
Onchocerca volvulus 0.0029 0.0025 0.0262
Echinococcus granulosus Glycosyl transferase family 35 0.0085 0.014 0.0379
Onchocerca volvulus 0.007 0.0109 0.1344
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0031 0.0088
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0198 0.0367 0.1292
Loa Loa (eye worm) hypothetical protein 0.1579 0.3157 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0062 0.0093 0.1671
Trypanosoma brucei unspecified product 0.0019 0.0005 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0225 0.0781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Echinococcus multilocularis 6 phosphofructokinase 0.0213 0.0397 0.0393
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0025 0.007
Brugia malayi beta-lactamase 0.0061 0.009 0.0274
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.0397 0.1399
Brugia malayi jmjC domain containing protein 0.0094 0.0158 0.0489
Echinococcus multilocularis heat shock protein 90 0.0088 0.0144 0.014
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0061 0.0089 0.027
Toxoplasma gondii hypothetical protein 0.0062 0.0093 0.0316
Loa Loa (eye worm) hypothetical protein 0.0146 0.0261 0.0815
Echinococcus multilocularis survival motor neuron protein 1 0.0951 0.1888 0.1884
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0119 0.0207 0.5154
Brugia malayi Cathepsin L-like precursor 0.0021 0.0009 0.0018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0025 0.0073
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0096 0.0162 0.0502
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Schistosoma mansoni importin beta-1 0.0045 0.0057 0.0161
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0041 0.0116
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0005 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0025 0.0073
Leishmania major developmentally regulated phosphoprotein-like protein 0.1579 0.3157 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.01 0.0302
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0043 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0032 0.0032 0.0098
Toxoplasma gondii DNA topoisomerase 2, putative 0.0088 0.0144 0.0499
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.0436 0.0431
Echinococcus granulosus serine protein kinase ATM 0.0054 0.0077 0.0203
Echinococcus granulosus sentrin specific protease 7 0.0161 0.0292 0.0804
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0088 0.0144 0.0444
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0003
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0043 0.0119
Echinococcus granulosus cathepsin l cysteine peptidase 0.0031 0.003 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-49 0.006 0.0089 0.0271
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0088 0.0144 0.3735
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.006 0.0089 0.0085
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0089 0.0271
Mycobacterium leprae Probable lipase LipE 0.0061 0.009 0.2179
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0233 0.0437 0.1222
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0005 0.0015
Toxoplasma gondii exonuclease III APE 0.0036 0.0039 0.0123
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0261 0.0257
Plasmodium vivax glutathione reductase, putative 0.0033 0.0034 0.0814
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.01 0.0302
Trypanosoma brucei metacaspase MCA3 0.0062 0.0092 0.0278
Onchocerca volvulus 0.0031 0.003 0.0334
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Schistosoma mansoni aldehyde dehydrogenase 0.015 0.027 0.0755
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0153 0.0528
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0181 0.0333 0.117
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Echinococcus granulosus nibrin 0.0032 0.0032 0.0077
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0061 0.009 0.0301
Onchocerca volvulus Protein ultraspiracle homolog 0.006 0.0089 0.109
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0024 0.002
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.1579 0.3157 1
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0015
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0063 0.0094 0.0286
Brugia malayi hypothetical protein 0.0019 0.0005 0.0005
Echinococcus granulosus Protein patched homolog 1 0.0092 0.0153 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0034 0.0094
Trypanosoma cruzi DNA topoisomerase II, putative 0.0088 0.0144 0.0444
Schistosoma mansoni hypothetical protein 0.0089 0.0146 0.0408
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0041 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0029 0.0026 0.0076
Trichomonas vaginalis glycogen phosphorylase, putative 0.0085 0.014 0.0482
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0001
Trypanosoma cruzi metacaspase, putative 0.0062 0.0092 0.0278
Mycobacterium ulcerans hypothetical protein 0.013 0.0229 0.0798
Plasmodium falciparum acyl-CoA synthetase 0.0095 0.0159 0.4275
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0076 0.012 0.1541
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0041 0.0036
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0024 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Loa Loa (eye worm) hypothetical protein 0.0133 0.0236 0.0735
Mycobacterium tuberculosis Conserved protein 0.0061 0.009 0.1143
Echinococcus multilocularis dnaJ subfamily C 6 0.0063 0.0095 0.0091
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.015 0.027 0.0744
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.079 0.0786
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0092 0.0152 0.0415
Loa Loa (eye worm) hypothetical protein 0.0061 0.0089 0.027
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.1408 0.2812 0.8904
Trypanosoma brucei developmentally regulated phosphoprotein 0.1579 0.3157 1
Onchocerca volvulus 0.006 0.0089 0.109
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0088 0.0144 0.1869
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0016
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0088 0.0144 0.0499
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Schistosoma mansoni caspase-7 (C14 family) 0.0091 0.015 0.042
Echinococcus granulosus Niemann Pick C1 protein 0.0214 0.04 0.1107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0015
Loa Loa (eye worm) steroid hormone receptor 0.006 0.0089 0.0268
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Echinococcus multilocularis peptidase Clp (S14 family) 0.0119 0.0207 0.0202
Echinococcus granulosus 6 phosphofructokinase 0.0213 0.0397 0.11
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Mycobacterium ulcerans aldehyde dehydrogenase 0.015 0.027 0.0942
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0121
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0024 0.0066
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0088 0.0144 0.1805
Loa Loa (eye worm) acetyltransferase 0.0233 0.0437 0.1371
Mycobacterium ulcerans glutaminase 0.0868 0.172 0.6109
Brugia malayi CXXC zinc finger family protein 0.0029 0.0025 0.0067
Trypanosoma brucei glucosidase, putative 0.0029 0.0025 0.0065
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0043 0.0121
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.1408 0.2812 0.8904
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0086
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0041 0.0118
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0121 0.0328
Echinococcus granulosus FTZ F1 alpha 0.0436 0.0847 0.2361
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0043 0.0136
Onchocerca volvulus 0.0198 0.0367 0.4676
Plasmodium vivax 6-phosphofructokinase, putative 0.0058 0.0083 0.2171
Giardia lamblia PHD finger protein 15 0.0029 0.0025 0.0573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0037 0.0103
Schistosoma mansoni glutaminase 0.0868 0.172 0.4812
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0096 0.0162 0.0499
Brugia malayi Papain family cysteine protease containing protein 0.0031 0.003 0.0085
Schistosoma mansoni caspase-3 (C14 family) 0.0164 0.0298 0.0833
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0043 0.0136
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Schistosoma mansoni topbp1 0.0032 0.0032 0.0089
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0029 0.0026 0.006
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Mycobacterium tuberculosis Probable reductase 0.0076 0.012 0.1541
Giardia lamblia DINP protein human, muc B family 0.0019 0.0005 0.003
Mycobacterium leprae Probable two component sensor kinase MprB 0.0088 0.0144 0.3565
Schistosoma mansoni lamin 0.007 0.0109 0.0304
Brugia malayi hypothetical protein 0.0029 0.0024 0.0066
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0552 0.1082 0.3419
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0034 0.0394
Echinococcus multilocularis musashi 0.007 0.0109 0.0104
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0041 0.0102
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0088 0.0144 0.1869
Brugia malayi hypothetical protein 0.0106 0.0182 0.0565
Plasmodium falciparum glutathione reductase 0.0033 0.0034 0.0814
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0029 0.0026 0.0072
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0043 0.0132
Brugia malayi AMP-binding enzyme family protein 0.0128 0.0225 0.0701
Trypanosoma brucei DNA topoisomerase ii 0.0088 0.0144 0.0444
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0088 0.0144 0.0495
Echinococcus multilocularis sterol regulatory element binding protein 0.0092 0.0153 0.0148
Brugia malayi DnaJ domain containing protein 0.0063 0.0095 0.029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0024 0.002
Schistosoma mansoni nuclear receptor 0.0029 0.0024 0.0068
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0043 0.1052
Mycobacterium tuberculosis Probable lipase LipE 0.0061 0.009 0.1143
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0043 0.0132
Schistosoma mansoni ap endonuclease 0.0036 0.0039 0.0109
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0034 0.0083
Brugia malayi exodeoxyribonuclease III family protein 0.0036 0.0039 0.0112
Echinococcus multilocularis apoptotic protease activating factor 1 0.0029 0.0025 0.0021
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0096 0.0162 0.0453
Echinococcus multilocularis microtubule associated protein 2 0.1786 0.3575 0.3572
Schistosoma mansoni steroid hormone receptor ad4bp 0.006 0.0089 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0089 0.0271
Trichomonas vaginalis importin beta-1, putative 0.0036 0.004 0.0128
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0041 0.0114
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0182 0.4893
Onchocerca volvulus 0.0194 0.0359 0.4568
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.0025 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0149 0.193
Loa Loa (eye worm) hypothetical protein 0.0045 0.0057 0.0168
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0031 0.003 0.0082
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0033 0.0034 0.0104
Onchocerca volvulus 0.0061 0.009 0.1103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Trypanosoma brucei heat shock protein 90, putative 0.0088 0.0144 0.0444
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0194 0.0358 0.0991
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0024 0.002
Echinococcus granulosus Niemann Pick C1 protein 0.0306 0.0585 0.1628
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.051
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0198 0.0367 0.1292
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0043 0.0123
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0041 0.0116
Loa Loa (eye worm) glutathione reductase 0.0033 0.0034 0.0094
Brugia malayi Cathepsin L-like precursor 0.0021 0.0009 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.006 0.0089 0.0268
Echinococcus multilocularis nibrin 0.0032 0.0032 0.0028
Onchocerca volvulus 0.0061 0.009 0.1103
Echinococcus multilocularis expressed protein 0.0369 0.0713 0.0709
Mycobacterium ulcerans beta-lactamase 0.0061 0.009 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.009 0.0271
Brugia malayi hypothetical protein 0.0032 0.0031 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0061 0.009 0.236
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0024 0.0068
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0129 0.0228 0.0712
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0031 0.0076
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0005 0.0002
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0367 0.115
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0367 0.115
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.006 0.0089 0.0085
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0005 0.0004
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0043 0.051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Onchocerca volvulus 0.0128 0.0225 0.2838
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.0436 0.1218
Schistosoma mansoni DNA polymerase eta 0.0019 0.0005 0.0015
Plasmodium falciparum phd finger protein, putative 0.0029 0.0025 0.0573
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.064 0.126 0.4471
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0096 0.0162 0.0157
Schistosoma mansoni hypothetical protein 0.0194 0.0359 0.1003
Entamoeba histolytica glycogenphosphorylase, putative 0.0037 0.0042 0.0132
Trypanosoma cruzi importin beta-1 subunit, putative 0.0036 0.004 0.0114
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0043 0.0123
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0029 0.0026 0.0021
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0019 0.0004 0.0012
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0088 0.0144 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Echinococcus granulosus muscleblind protein 0.0146 0.0261 0.072
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0086
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0032 0.0098
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0005 0.0003
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0041 0.0102
Schistosoma mansoni hypothetical protein 0.0089 0.0146 0.0408
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0005 0.0005
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0037 0.0033
Echinococcus granulosus sterol regulatory element binding protein 0.0092 0.0153 0.0415
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0015
Loa Loa (eye worm) peptidase family M13 containing protein 0.0046 0.0061 0.0179
Onchocerca volvulus Cell death protein 3 homolog 0.0091 0.015 0.1881
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0059 0.0086 0.1085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0029 0.0026 0.0076
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0088 0.0144 0.0495
Trypanosoma cruzi cysteine peptidase, putative 0.0031 0.003 0.0082
Plasmodium falciparum endoplasmin, putative 0.0088 0.0144 0.386
Echinococcus multilocularis lysosomal alpha glucosidase 0.0129 0.0228 0.0224
Echinococcus multilocularis thyroid hormone receptor alpha 0.006 0.0089 0.0085
Trypanosoma cruzi target of rapamycin kinase 3 0.0096 0.0162 0.0499
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0162 0.0294 0.0289
Plasmodium falciparum metacaspase-like protein 0.0062 0.0092 0.2416
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.1579 0.3157 0.8832
Schistosoma mansoni glycogen phosphorylase 0.0085 0.014 0.0391
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.0397 0.1399
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0062 0.0092 0.0257
Mycobacterium ulcerans lipase LipD 0.0061 0.009 0.0301
Entamoeba histolytica hypothetical protein 0.0019 0.0005 0.0003
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Loa Loa (eye worm) hypothetical protein 0.0133 0.0236 0.0735
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0024 0.0056
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.051
Schistosoma mansoni hypothetical protein 0.0715 0.1411 0.3946
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.006 0.0089 0.0237
Loa Loa (eye worm) glutaminase 2 0.0868 0.172 0.5441
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0043 0.0136
Onchocerca volvulus Alhambra homolog 0.0029 0.0025 0.0268
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.015 0.027 0.3547
Schistosoma mansoni survival motor neuron protein 0.0194 0.0359 0.1003
Schistosoma mansoni hypothetical protein 0.0478 0.0933 0.2611
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.01 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0031 0.003 0.0092
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0367 0.1292
Onchocerca volvulus 0.0031 0.003 0.0334
Trypanosoma brucei heat shock protein, putative 0.0088 0.0144 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0005 0.0001
Echinococcus multilocularis peregrin 0.0035 0.0037 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0041 0.013
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0182 0.4893
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0096 0.0162 0.0499
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0037 0.0043 0.0132
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.023
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.006 0.0089 0.0268
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Loa Loa (eye worm) hypothetical protein 0.0092 0.0153 0.047
Onchocerca volvulus 0.0037 0.0043 0.0492
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0068 0.0105 0.0359
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0024 0.0066
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0059 0.0086 0.207
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0029 0.0026 0.0076
Trypanosoma brucei metacaspase MCA2 0.0062 0.0092 0.0278
Brugia malayi heat shock protein 90 0.0088 0.0144 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0031 0.003 0.0092
Trypanosoma cruzi cruzipain precursor, putative 0.0031 0.003 0.0082
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0058 0.0083 0.028
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0005 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0031 0.0088
Entamoeba histolytica steroid 5-alpha reductase, putative 0.1408 0.2812 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0066 0.01 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.0436 0.1208
Loa Loa (eye worm) hypothetical protein 0.007 0.0109 0.0331
Giardia lamblia Thymus-specific serine protease precursor 0.0029 0.0026 0.0587
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.0043 0.051
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0198 0.0367 0.1016
Brugia malayi beta-lactamase family protein 0.0061 0.009 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0039 0.095
Echinococcus multilocularis inositol monophosphatase 1 0.0066 0.01 0.0095
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0024 0.0064
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0088 0.0144 0.0444
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0043 0.0121
Brugia malayi RNA, U transporter 1 0.0127 0.0224 0.07
Schistosoma mansoni DNA topoisomerase II 0.0088 0.0144 0.0404
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Toxoplasma gondii peptidase family M13 protein 0.0063 0.0094 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0015
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.029 0.0553 0.1743
Trichomonas vaginalis inositol monophosphatase, putative 0.0066 0.01 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0128 0.0225 0.294
Brugia malayi Intermediate filament tail domain containing protein 0.007 0.0109 0.0333
Echinococcus multilocularis expressed conserved protein 0.0201 0.0373 0.0369
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0025 0.0065
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0043 0.0038
Onchocerca volvulus 0.0031 0.003 0.0334
Entamoeba histolytica glycogen phosphorylase, putative 0.0037 0.0042 0.0132
Trichomonas vaginalis DNA topoisomerase II, putative 0.0088 0.0144 0.0499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0031 0.003 0.0082
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.006 0.0089 0.0249
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0041 0.0116
Schistosoma mansoni cathepsin F (C01 family) 0.0021 0.0009 0.0026
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.007
Schistosoma mansoni hypothetical protein 0.0092 0.0152 0.0426
Entamoeba histolytica hypothetical protein 0.0076 0.0121 0.0417
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0445 0.1398
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.006 0.0089 0.0268
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0024 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0089 0.0085
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0161 0.0292 0.1023
Loa Loa (eye worm) TAR-binding protein 0.0382 0.0739 0.233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Loa Loa (eye worm) cysteine protease 0.0031 0.003 0.0082
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0213 0.0397 0.1245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0089 0.0271
Onchocerca volvulus 0.0402 0.078 1
Schistosoma mansoni ran 0.0033 0.0034 0.0094
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0164 0.0298 0.0822
Mycobacterium tuberculosis Conserved protein 0.0088 0.0144 0.1869
Loa Loa (eye worm) endoplasmin 0.0088 0.0144 0.0444
Chlamydia trachomatis UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 0.1336 0.2667 1
Brugia malayi 6-phosphofructokinase 0.0213 0.0397 0.1249
Chlamydia trachomatis glycogen phosphorylase 0.0085 0.014 0.0408
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.0182 0.0632
Trypanosoma brucei heat shock protein 90, putative 0.0088 0.0144 0.0444
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0182 0.0563
Leishmania major 4-coumarate:coa ligase-like protein 0.0128 0.0225 0.0698
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Echinococcus multilocularis serine protein kinase ATM 0.0054 0.0077 0.0072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0061 0.009 0.0252
Echinococcus granulosus apoptotic protease activating factor 1 0.0029 0.0025 0.0058
Giardia lamblia Heat shock protein HSP 90-alpha 0.0088 0.0144 0.386
Mycobacterium tuberculosis Probable two component sensor kinase 0.0088 0.0144 0.1869
Loa Loa (eye worm) hypothetical protein 0.0095 0.0159 0.0492
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0128 0.0225 0.294
Echinococcus multilocularis tar DNA binding protein 0.0382 0.0739 0.0735
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0032 0.0032 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0098
Schistosoma mansoni hypothetical protein 0.0408 0.079 0.2211
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0029 0.0026 0.0076
Echinococcus multilocularis ecdysone induced protein 78C 0.006 0.0089 0.0085
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0019 0.0004 0.0012
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0088 0.0144 0.014
Leishmania major mitochondrial DNA polymerase beta 0.0247 0.0465 0.1462
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0367 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0096 0.0162 0.0499
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.1408 0.2812 0.8905
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0041 0.0114
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0088 0.0144 0.0499
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Trichomonas vaginalis bromodomain-containing protein, putative 0.0068 0.0105 0.0359
Toxoplasma gondii HEAT repeat-containing protein 0.0045 0.0057 0.0189
Mycobacterium tuberculosis Probable dehydrogenase 0.0076 0.012 0.1541
Schistosoma mansoni thyroid hormone receptor 0.006 0.0089 0.0249
Echinococcus granulosus GTP binding nuclear protein Ran 0.0033 0.0034 0.0082
Plasmodium vivax DNA gyrase subunit B, putative 0.0088 0.0144 0.386
Schistosoma mansoni aldehyde dehydrogenase 0.015 0.027 0.0755
Plasmodium falciparum metacaspase 1 0.0062 0.0092 0.2416
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0036 0.0039 0.046
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0043 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trypanosoma cruzi heat shock protein 85, putative 0.0088 0.0144 0.0444
Echinococcus granulosus lamin dm0 0.007 0.0109 0.0292
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0039 0.0123
Plasmodium vivax vivapain-2 0.0031 0.003 0.0715
Trichomonas vaginalis esterase, putative 0.0061 0.009 0.0305
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0088 0.0144 0.0495
Mycobacterium tuberculosis Conserved protein 0.0061 0.009 0.1143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0009 0.0018
Trichomonas vaginalis glycogen phosphorylase, putative 0.0085 0.014 0.0482
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0032 0.0031 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0076 0.012 0.2939
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0198 0.0367 0.1027
Echinococcus granulosus glycogen phosphorylase 0.0085 0.014 0.0379
Loa Loa (eye worm) 6-phosphofructokinase 0.0213 0.0397 0.1245
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.006 0.0089 0.0249
Schistosoma mansoni coup transcription factor 0.006 0.0089 0.0249
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Onchocerca volvulus Cathepsin L homolog 0.0031 0.003 0.0334
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.0025 0.0073
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0024 0.0066
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0019 0.0004 0.0012
Brugia malayi TAR-binding protein 0.0382 0.0739 0.2332
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.029 0.0553 0.1743
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0015
Brugia malayi hypothetical protein 0.0029 0.0024 0.0066
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0054 0.0077 0.0215
Echinococcus multilocularis FTZ F1 alpha 0.006 0.0089 0.0085
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0088 0.0144 0.1805
Trichomonas vaginalis endoplasmin, putative 0.0088 0.0144 0.0499
Leishmania major mitochondrial DNA topoisomerase II 0.0088 0.0144 0.0444
Brugia malayi glutathione reductase 0.0033 0.0034 0.0096
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0158 0.0153
Schistosoma mansoni lamin 0.007 0.0109 0.0304
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0029 0.0026 0.0076
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0066 0.01 0.2246
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.006 0.0089 0.0249
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0068 0.0105 0.2776
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.009
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0096 0.0162 0.0441
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0002
Brugia malayi Serine carboxypeptidase S28 family protein 0.0133 0.0236 0.0737
Echinococcus granulosus heat shock protein 90 0.0088 0.0144 0.0392
Echinococcus granulosus endothelin converting enzyme 1 0.0063 0.0094 0.025
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.0025 0.0065
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0149 0.193
Toxoplasma gondii ABC1 family protein 0.0061 0.009 0.0305
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Loa Loa (eye worm) hypothetical protein 0.0128 0.0225 0.0698
Echinococcus multilocularis cysteine protease 0.0031 0.003 0.0026
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0043 0.0121
Mycobacterium ulcerans hypothetical protein 0.1408 0.2812 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Brugia malayi hypothetical protein 0.0402 0.078 0.2462
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0063 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0552 0.1082 0.3419
Schistosoma mansoni tar DNA-binding protein 0.0382 0.0739 0.2067
Brugia malayi nuclear receptor NHR-67 0.0029 0.0024 0.0066
Loa Loa (eye worm) TOPoisomerase family member 0.0088 0.0144 0.0444
Brugia malayi ecdysone receptor 0.0029 0.0024 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-3 0.006 0.0089 0.0271
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0 0.0001
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0019 0.0004 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0225 0.0781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0144 0.386
Loa Loa (eye worm) hypothetical protein 0.0214 0.04 0.1254
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.0032 0.0098
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0025 0.0067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0031 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.009 0.025
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0024 0.0068
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0198 0.0367 0.0363
Loa Loa (eye worm) hypothetical protein 0.0049 0.0067 0.0198
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0128 0.0225 0.5607
Onchocerca volvulus 0.0031 0.003 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0025 0.0073
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.006 0.0089 0.0237
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0032 0.0031 0.0086
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0031 0.003 0.0026
Schistosoma mansoni hypothetical protein 0.0089 0.0146 0.0408
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0089 0.0271
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0084 0.0137 0.1769
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.009 0.0271
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0016
Schistosoma mansoni peptidase Clp (S14 family) 0.0181 0.0333 0.0931
Schistosoma mansoni topbp1 0.0032 0.0032 0.0089
Trypanosoma brucei Heat shock protein 83, putative 0.0088 0.0144 0.0444
Trichomonas vaginalis ran, putative 0.0033 0.0034 0.0104
Echinococcus granulosus peregrin 0.0035 0.0037 0.009
Toxoplasma gondii aldehyde dehydrogenase 0.015 0.027 0.0946
Echinococcus multilocularis lamin dm0 0.007 0.0109 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0089 0.0303
Brugia malayi Muscleblind-like protein 0.0146 0.0261 0.0818
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0036 0.0039 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0098
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0096 0.0162 0.0499
Brugia malayi jmjC domain containing protein 0.0037 0.0041 0.0118
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0121 0.0339
Loa Loa (eye worm) latrophilin receptor protein 2 0.0092 0.0152 0.047
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0024 0.0056
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0005 0.0003
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0198 0.0367 0.1292
Echinococcus granulosus caspase 2 0.0091 0.015 0.0409
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0031 0.003 0.0092
Plasmodium vivax vivapain-2 0.0031 0.003 0.0715
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0004 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.006 0.0089 0.0268
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1408 0.2812 0.8904
Giardia lamblia Synaptic glycoprotein SC2 0.0198 0.0367 1
Brugia malayi photoreceptor-specific nuclear receptor 0.006 0.0089 0.0271
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0151
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0043 0.0972
Loa Loa (eye worm) heat shock protein 90 0.0088 0.0144 0.0444
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0015
Schistosoma mansoni pyruvate dehydrogenase 0.1491 0.298 0.8336
Brugia malayi Cathepsin L-like precursor 0.0031 0.003 0.0085
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0061 0.009 0.1143
Plasmodium vivax polyprenol reductase, putative 0.0198 0.0367 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0041 0.0036
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0066
Loa Loa (eye worm) hypothetical protein 0.0095 0.0159 0.0492
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0032 0.0087
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0005
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0032 0.0032 0.0703
Trypanosoma brucei importin beta-1 subunit, putative 0.0045 0.0057 0.0168
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1579 0.3157 0.3154
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.1408 0.2812 0.8904
Loa Loa (eye worm) hypothetical protein 0.0092 0.0152 0.047
Brugia malayi hypothetical protein 0.0069 0.0106 0.0324
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0005 0.0003
Schistosoma mansoni heat shock protein 0.0088 0.0144 0.0404
Echinococcus multilocularis geminin 0.0715 0.1411 0.1407
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0043 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0031 0.003 0.0092
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0033 0.0034 0.0092
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0198 0.0367 0.1027
Brugia malayi Cathepsin L-like cysteine proteinase 0.0021 0.0009 0.0018
Loa Loa (eye worm) phosphofructokinase 0.0213 0.0397 0.1245
Schistosoma mansoni hypothetical protein 0.0092 0.0152 0.0426
Mycobacterium ulcerans acyl-CoA synthetase 0.0128 0.0225 0.0781
Schistosoma mansoni microtubule-associated protein tau 0.1786 0.3575 1
Schistosoma mansoni 6-phosphofructokinase 0.0213 0.0397 0.1111
Leishmania major heat shock protein 83-1 0.0088 0.0144 0.0444
Toxoplasma gondii 6-phosphofructokinase 0.0058 0.0083 0.028
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0096 0.0162 0.0499
Leishmania major ATP-dependent phosphofructokinase 0.0213 0.0397 0.1245
Brugia malayi DKFZp564C0469 protein 0.0032 0.0032 0.009
Mycobacterium ulcerans putative regultory protein 0.0088 0.0144 0.0495
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.1142
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.0032 0.0098
Schistosoma mansoni inositol monophosphatase 0.0066 0.01 0.0278
Echinococcus multilocularis glycogen phosphorylase 0.0085 0.014 0.0135
Loa Loa (eye worm) phosphatidylinositol 3 0.0096 0.0162 0.0499
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0005 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.0397 0.1399
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0041 0.0036
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0015
Entamoeba histolytica hypothetical protein 0.0076 0.0121 0.0417
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0648 0.1277 0.3572
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0088 0.0144 0.3735
Plasmodium vivax heat shock protein 86, putative 0.0088 0.0144 0.386
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0041 0.0102
Schistosoma mansoni patched 1 0.0092 0.0153 0.0427
Trichomonas vaginalis D-aminoacylase, putative 0.0061 0.009 0.0305
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0083 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.006 0.0089 0.0268
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0092 0.0312
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0024 0.0066
Echinococcus granulosus glycogen phosphorylase 0.0085 0.014 0.0379
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0043 0.0132
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0092 0.0152 0.0148
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0088 0.0144 0.0427
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0005 0.0003
Giardia lamblia Serine peptidase, putative 0.0029 0.0026 0.0587
Trichomonas vaginalis D-aminoacylase, putative 0.0061 0.009 0.0305
Brugia malayi Serine protease Z688.6 precursor 0.0029 0.0026 0.007
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0037 0.0043 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0077 0.0258
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0005 0.0004
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0088 0.0144 0.0495
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0214 0.04 0.1408
Leishmania major cathepsin L-like protease 0.0031 0.003 0.0082
Brugia malayi Serine protease Z688.6 precursor 0.0029 0.0026 0.007
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0043 0.0121
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0024 0.0068
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0062 0.0093 0.2256
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0036 0.0039 0.0109
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0064
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0061 0.0089 0.0303
Entamoeba histolytica glycogen phosphorylase, putative 0.0085 0.014 0.0482
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0025 0.0073
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0181 0.0333 0.9058
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1579 0.3157 0.3154
Loa Loa (eye worm) hypothetical protein 0.0088 0.0144 0.0444
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0005
Brugia malayi carbohydrate phosphorylase 0.0085 0.014 0.0431
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0058 0.0083 0.1401
Echinococcus granulosus cpg binding protein 0.003 0.0028 0.0066
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0088 0.0144 0.1869
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0146 0.0261 0.0815
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0029 0.0026 0.0076
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.007
Chlamydia trachomatis DNA gyrase subunit B 0.0088 0.0144 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0162 0.0561
Echinococcus multilocularis GPCR, family 2 0.0092 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0086
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0382 0.0739 0.233
Entamoeba histolytica cysteine proteinase, putative 0.0031 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0086
Schistosoma mansoni heat shock protein 0.0088 0.0144 0.0404
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0024 0.0056
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0062 0.0092 0.0312
Trypanosoma cruzi DNA topoisomerase II, putative 0.0088 0.0144 0.0444
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0088 0.0144 0.0446
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0029 0.0026 0.0076
Brugia malayi beta-lactamase family protein 0.0061 0.009 0.0274
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0268
Onchocerca volvulus 0.0031 0.003 0.0327
Entamoeba histolytica hypothetical protein 0.0032 0.0032 0.0098
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0096 0.0162 0.0499
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0043 0.0132
Onchocerca volvulus 0.0021 0.0009 0.0064

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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