Detailed information for compound 1250229

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 224.213 | Formula: C10H12N2O4
  • H donors: 1 H acceptors: 2 LogP: -0.4 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@@H]2C[C@@H]1Oc1n2cc(c(=O)n1)C
  • InChi: 1S/C10H12N2O4/c1-5-3-12-8-2-6(7(4-13)15-8)16-10(12)11-9(5)14/h3,6-8,13H,2,4H2,1H3/t6-,7+,8+/m0/s1
  • InChiKey: JCSNHEYOIASGKU-XLPZGREQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.001 0.0079
Trypanosoma brucei beta tubulin 0.0025 0.0055 0.0469
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0031 0.0031
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0145 0.0954
Trypanosoma cruzi oligopeptidase b 0.0032 0.0083 0.0719
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.003 0.0255
Giardia lamblia GTOR 0.0018 0.0031 0.2266
Trichomonas vaginalis cyclins, putative 0.003 0.0075 0.5631
Trichomonas vaginalis tubulin alpha chain, putative 0.0014 0.0014 0.0952
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0358 0.1144
Trichomonas vaginalis cyclin D, putative 0.0018 0.003 0.2207
Loa Loa (eye worm) beta-tubulin 0.0025 0.0055 0.0361
Loa Loa (eye worm) alpha-tubulin 0.0033 0.0087 0.0575
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0304
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0106 0.8028
Loa Loa (eye worm) hypothetical protein 0.0104 0.036 0.2373
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0222
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0106 0.8028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.009 0.1527
Mycobacterium ulcerans oxidoreductase 0.0021 0.0042 0.0698
Schistosoma mansoni hypothetical protein 0.034 0.1269 0.4051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0317 0.1013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0317 0.1013
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0127 0.1097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0521 0.4543
Trypanosoma brucei epsilon tubulin 0.0025 0.0055 0.0469
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0024 0.0076
Onchocerca volvulus Alhambra homolog 0.0032 0.0082 0.0537
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0521 0.4543
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0132 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0136 0.0484 0.4219
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.029 0.3233
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0106 0.1177
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0317 0.2091
Brugia malayi Ets-domain containing protein 0.0072 0.0237 0.1562
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0127 0.1097
Trichomonas vaginalis tubulin gamma chain, putative 0.0025 0.0055 0.4094
Echinococcus granulosus peregrin 0.0035 0.0095 0.0304
Brugia malayi Ets-domain containing protein 0.001 0 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0821 0.262
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0032 0.0083 0.5221
Giardia lamblia Beta tubulin 0.0025 0.0055 0.4094
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0082 0.0082
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0405 0.1519 0.4848
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0136 0.0484 0.4219
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0145 0.0954
Plasmodium falciparum alpha tubulin 2 0.0033 0.0087 0.1034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Leishmania major mitochondrial DNA polymerase beta 0.0308 0.1146 1
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0125 0.0399
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0012 0.0038
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.001 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.001 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0132 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus multilocularis tubulin beta 1 chain 0.0025 0.0055 0.0055
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0136 0.0484 0.1545
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Schistosoma mansoni tubulin subunit gamma 0.0025 0.0055 0.0175
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0009 0.0084
Mycobacterium ulcerans hypothetical protein 0.0038 0.0106 0.1805
Plasmodium falciparum alpha tubulin 1 0.0033 0.0087 0.1034
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0056 0.0615
Brugia malayi beta-tubulin, identical 0.0025 0.0055 0.0361
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0405 0.1519 1
Schistosoma mansoni gabp alpha 0.0072 0.0237 0.0757
Echinococcus multilocularis GPCR, family 2 0.0048 0.0145 0.0145
Echinococcus granulosus tubulin alpha 3 chain 0.0033 0.0087 0.0279
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0013 0.0009 0.0065
Loa Loa (eye worm) beta-lactamase 0.0038 0.0106 0.0701
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0045 0.0132 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0136 0.0484 0.1526
Trichomonas vaginalis tubulin gamma chain, putative 0.0025 0.0055 0.4094
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.003 0.05
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Echinococcus multilocularis tubulin delta chain 0.0011 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0132 1
Trypanosoma cruzi epsilon tubulin, putative 0.0025 0.0055 0.0469
Loa Loa (eye worm) BEN-1 protein 0.0025 0.0055 0.0361
Schistosoma mansoni cyclins 0.0018 0.003 0.0096
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0107 0.0341
Loa Loa (eye worm) tubulin beta chain 0.0025 0.0055 0.0361
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0896 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0057 0.0183
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0136 0.0484 0.4219
Echinococcus granulosus Tubulin alpha 1 chain 0.0033 0.0087 0.0279
Plasmodium vivax tubulin beta chain, putative 0.0025 0.0055 0.0644
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0032 0.0083 0.0266
Entamoeba histolytica prolyl oligopeptidase family protein 0.0032 0.0083 0.5221
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0237 0.1562
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0013 0.0009 0.0128
Entamoeba histolytica tubulin family protein 0.0025 0.0055 0.2421
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0042 0.0698
Trichomonas vaginalis tubulin epsilon chain, putative 0.0033 0.0087 0.6577
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.029 0.3233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0029
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0127 0.1097
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0057 0.0178
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0056 0.0943
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0358 0.0358
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.003 0.2223
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0327 0.3645
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0021 0.0042 0.0488
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0056 0.0943
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0056 0.0943
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0132 1
Echinococcus multilocularis cyclin b3 0.0018 0.003 0.003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0042 0.0698
Echinococcus granulosus tubulin alpha chain 0.0033 0.0087 0.0279
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0031 0.0098
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0145 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Plasmodium falciparum phd finger protein, putative 0.0032 0.0082 0.0964
Echinococcus multilocularis cyclin B 0.0044 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0125 0.9451
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Onchocerca volvulus 0.0013 0.0009 0.0056
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.1146 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0522 0.1665
Trypanosoma cruzi tubulin gamma chain 0.0025 0.0055 0.0469
Brugia malayi Tubulin gamma chain 0.0025 0.0055 0.0361
Brugia malayi Raf kinase 0.0216 0.0791 0.5207
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0 0.0001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.029 0.3233
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Brugia malayi Cyclin, N-terminal domain containing protein 0.0044 0.0128 0.0844
Brugia malayi Tubulin beta chain 0.0011 0.0001 0.0007
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0031 0.0098
Schistosoma mansoni dihydropteridine reductase 0.0013 0.0009 0.0027
Brugia malayi jmjC domain containing protein 0.0103 0.0358 0.236
Mycobacterium tuberculosis Conserved protein 0.0038 0.0106 0.1177
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0125 0.0392
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0031 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0257
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0031 0.026
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0327 0.3645
Brugia malayi Thioredoxin reductase 0.0038 0.0105 0.069
Brugia malayi Ets-domain containing protein 0.0072 0.0237 0.1562
Trypanosoma brucei alpha tubulin 0.0033 0.0087 0.0754
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0105 0.1243
Echinococcus multilocularis Tubulin alpha 1 chain 0.0033 0.0087 0.0087
Brugia malayi jmjC domain containing protein 0.0042 0.012 0.0789
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0031 0.026
Loa Loa (eye worm) tubulin beta chain 0.0011 0.0001 0.0007
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0014 0.0013 0.0146
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0056 0.0174
Brugia malayi Bromodomain containing protein 0.0035 0.0095 0.0628
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.017 0.203
Echinococcus granulosus prolyl endopeptidase 0.0032 0.0083 0.0266
Toxoplasma gondii alpha tubulin TUBA1 0.0033 0.0087 0.0273
Toxoplasma gondii beta-hydroxyacyl-acyl carrier protein dehydratase (FABZ) 0.0227 0.0836 0.2638
Plasmodium falciparum enoyl-acyl carrier reductase 0.0013 0.0009 0.009
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0012 0.0005 0.0015
Trypanosoma cruzi cyclin 6, putative 0.0044 0.0128 0.1111
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0025 0.0055 0.0055
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0106 0.1805
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0042 0.0275
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0013 0.0009 0.0229
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0056 0.0615
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Brugia malayi CXXC zinc finger family protein 0.0058 0.0183 0.1203
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0585 0.6519
Echinococcus multilocularis acylamino acid releasing enzyme 0.0032 0.0083 0.0083
Trichomonas vaginalis cyclin A, putative 0.0044 0.0128 0.9689
Mycobacterium tuberculosis Conserved protein 0.0038 0.0106 0.1177
Trypanosoma brucei epsilon tubulin 0.0025 0.0055 0.0469
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0044 0.0128 0.1111
Trichomonas vaginalis tubulin, putative 0.0025 0.0055 0.4094
Plasmodium falciparum thioredoxin reductase 0.0013 0.001 0.0108
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0004 0.0029
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0024 0.0076
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.001 0.0032
Schistosoma mansoni hypothetical protein 0.0025 0.0054 0.0173
Echinococcus granulosus cyclins 0.0018 0.003 0.0096
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0506 0.1615
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0056 0.0615
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0396 0.1247
Leishmania major cytochrome p450-like protein 0.0025 0.0056 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0156
Trypanosoma brucei alpha tubulin 0.0033 0.0087 0.0754
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0012 0.0005 0.003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.003 0.0021
Schistosoma mansoni tubulin subunit alpha 0.0011 0.0001 0.0003
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0132 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0056 0.0615
Entamoeba histolytica tubulin alpha chain, putative 0.0033 0.0087 0.5607
Echinococcus multilocularis beta tubulin 0.0025 0.0055 0.0055
Loa Loa (eye worm) tubulin beta-4 chain 0.0025 0.0055 0.0361
Brugia malayi prolyl oligopeptidase family protein 0.0032 0.0083 0.0549
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0056 0.0943
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0105 0.0906
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0132 0.1146
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0145 0.0145
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0031 0.0261
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0132 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Trichomonas vaginalis tubulin beta chain, putative 0.0025 0.0055 0.4094
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0106 0.8028
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0056 0.0615
Mycobacterium tuberculosis Probable peptidase 0.0032 0.0083 0.092
Echinococcus granulosus Smad4 0.0017 0.0024 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.0102 0.0353 0.2322
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0056 0.0943
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0317 0.1013
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0056 0.0481
Schistosoma mansoni Smad4 0.0017 0.0024 0.0076
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0084
Giardia lamblia Alanyl dipeptidyl peptidase 0.0032 0.0083 0.6276
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0056 0.0481
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.001 0.0079
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0054 0.0173
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.001 0.001
Trypanosoma cruzi CYC2-like cyclin, putative 0.0044 0.0128 0.1111
Onchocerca volvulus 0.0021 0.0042 0.0275
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0024 0.0156
Trichomonas vaginalis tubulin, putative 0.0014 0.0014 0.0952
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Giardia lamblia Alpha-tubulin 0.0033 0.0087 0.6577
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0125 0.9451
Trypanosoma brucei beta tubulin 0.0025 0.0055 0.0469
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0082 0.026
Echinococcus granulosus Dipeptidyl peptidase 9 0.0136 0.0484 0.1545
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0327 0.3645
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0128
Trypanosoma brucei prolyl oligopeptidase, putative 0.0032 0.0083 0.0719
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0844
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0132 0.0871
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0056 0.0481
Echinococcus multilocularis tubulin alpha 0.0025 0.0055 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0032 0.0083 0.026
Echinococcus multilocularis geminin 0.034 0.1269 0.1269
Trypanosoma brucei alpha tubulin 0.0033 0.0087 0.0754
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Loa Loa (eye worm) D-ets-2 protein 0.001 0 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0327 1
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0055 0.017 0.1122
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0024 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Echinococcus multilocularis beta tubulin 0.0025 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0056 0.0615
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0082 0.0964
Loa Loa (eye worm) ets-domain-containing protein 0.001 0 0.0001
Plasmodium falciparum peptidase, putative 0.0032 0.0083 0.0987
Trichomonas vaginalis cyclin B, putative 0.0044 0.0128 0.9689
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0031 0.026
Schistosoma mansoni tubulin subunit beta 0.0011 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0042 0.0698
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0012 0.0005 0.0015
Echinococcus granulosus cyclin B 0.0044 0.0128 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0056 0.0615
Brugia malayi Cyclin, N-terminal domain containing protein 0.0018 0.003 0.0198
Onchocerca volvulus 0.0038 0.0106 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Brugia malayi hypothetical protein 0.0055 0.017 0.1122
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0317 0.2091
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0009 0.0084
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0125 0.0392
Trichomonas vaginalis helicase, putative 0.0013 0.001 0.0706
Entamoeba histolytica prolyl oligopeptidase family protein 0.0032 0.0083 0.5221
Brugia malayi Cytochrome P450 family protein 0.0025 0.0056 0.0369
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.003 0.0255
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0031 0.0203
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Brugia malayi cell division control protein 2 homolog 0.0045 0.0132 0.0871
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0021 0.0042 0.0698
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.003 0.0255
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Leishmania major cytochrome p450-like protein 0.0034 0.009 0.0778
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0032 0.0083 0.0719
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0032 0.0083 0.0719
Echinococcus multilocularis tubulin alpha 1C chain 0.0033 0.0087 0.0087
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0032 0.0083 0.5221
Trypanosoma brucei oxidoreductase-like protein 0.0013 0.0009 0.0065
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Mycobacterium ulcerans beta-lactamase 0.0038 0.0106 0.1805
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0132 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0019 0.0034 0.2483
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0031 0.0261
Echinococcus granulosus c-Jun N-terminal kinases 0.0237 0.0873 0.2787
Trypanosoma cruzi alpha tubulin, putative 0.0033 0.0087 0.0754
Giardia lamblia PHD finger protein 15 0.0032 0.0082 0.6135
Loa Loa (eye worm) acetyltransferase 0.0146 0.0522 0.3435
Schistosoma mansoni tubulin subunit epsilon 0.0025 0.0055 0.0175
Onchocerca volvulus Prolyl endopeptidase homolog 0.0032 0.0083 0.0549
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0237 0.0237
Echinococcus multilocularis tubulin alpha chain 0.0033 0.0087 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus granulosus dnaJ subfamily B 0.0824 0.3133 1
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0042 0.0698
Leishmania major epsilon tubulin, putative 0.0025 0.0055 0.0469
Giardia lamblia Alpha-tubulin 0.0033 0.0087 0.6577
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0012 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0056 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Brugia malayi Tubulin alpha chain 0.0011 0.0001 0.0007
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Loa Loa (eye worm) cytochrome P450 0.0025 0.0056 0.0369
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0031 0.026
Loa Loa (eye worm) tubulin beta-2A chain 0.0025 0.0055 0.0361
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0106 0.1262
Trichomonas vaginalis tubulin beta chain, putative 0.0014 0.0014 0.0952
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0056 0.0615
Trichomonas vaginalis cyclins, putative 0.0044 0.0128 0.9689
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.001 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0056 0.0615
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.001 0.0032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.001 0.0028
Trypanosoma brucei epsilon tubulin 0.0025 0.0055 0.0469
Brugia malayi cytochrome P450 0.0025 0.0056 0.0369
Echinococcus granulosus alpha tubulin 0.0033 0.0087 0.0279
Trichomonas vaginalis tubulin alpha chain, putative 0.0014 0.0014 0.0952
Leishmania major cyclin 0.0044 0.0128 0.1111
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0106 0.8028
Echinococcus granulosus cpg binding protein 0.0061 0.0195 0.0624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus multilocularis peroxisome assembly protein 26 0.0033 0.0087 0.0087
Trichomonas vaginalis tubulin epsilon chain, putative 0.0033 0.0087 0.6577
Onchocerca volvulus 0.0044 0.0128 0.0844
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0032 0.0083 0.0266
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0042 0.0275
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0032 0.0083 0.0719
Schistosoma mansoni hypothetical protein 0.0104 0.036 0.1148
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0021 0.0042 0.1153
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.0545 0.3585
Echinococcus granulosus GPCR family 2 0.0048 0.0145 0.0462
Echinococcus granulosus Tubulin alpha 1 chain 0.0033 0.0087 0.0279
Plasmodium falciparum glutathione reductase 0.0013 0.001 0.0108
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0031 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0083 0.0719
Loa Loa (eye worm) cyclin domain-containing protein 0.0018 0.003 0.0198
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0145 0.0462
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0013 0.0009 0.0084
Schistosoma mansoni cyclin B 0.0044 0.0128 0.0409
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0 0.0001
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0013 0.0009 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0015 0.0015
Brugia malayi Tubulin beta chain 0.0014 0.0014 0.0089
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0132 0.0871
Echinococcus multilocularis prolyl endopeptidase 0.0032 0.0083 0.0083
Chlamydia trachomatis 3-hydroxyacyl-ACP dehydratase 0.0227 0.0836 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0013 0.0009 0.0056
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0021 0.0042 0.0129
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0128
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.001 0.0066
Giardia lamblia Alanyl dipeptidyl peptidase 0.0032 0.0083 0.6276
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0128
Trichomonas vaginalis cyclin B, putative 0.0044 0.0128 0.9689
Entamoeba histolytica tubulin family protein 0.0025 0.0055 0.2421
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.017 0.148
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0237 0.0873 0.5748
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.003 1
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0136 0.0484 0.0484
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0031 0.026
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0013 0.0009 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.009 0.0778
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0055 0.0175
Trypanosoma cruzi prolyl endopeptidase 0.0032 0.0083 0.0719
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0014 0.0014 0.0952
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0032 0.0083 0.6276
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0032 0.0083 0.2524
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0104 0.036 0.2367
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.003 0.0199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Plasmodium vivax beta-hydroxyacyl-ACP dehydratase precursor, putative 0.0227 0.0836 1
Echinococcus multilocularis Smad4 0.0017 0.0024 0.0024
Echinococcus granulosus cyclins 0.0018 0.003 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0056 0.0615
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Leishmania major hypothetical protein, conserved 0.0038 0.0106 0.092
Entamoeba histolytica tubulin gamma chain 0.0025 0.0055 0.2421
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.001 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0056 0.0615
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0057 0.0057
Brugia malayi Tubulin alpha-2 chain 0.0033 0.0087 0.0575
Schistosoma mansoni ap endonuclease 0.0018 0.003 0.0097
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0055 0.0055
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.003 0.003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0521 0.4543
Trichomonas vaginalis cyclins, putative 0.0044 0.0128 0.9689
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0057 0.0491
Toxoplasma gondii LsmAD domain-containing protein 0.0055 0.017 0.0535
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0111 0.8402
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0081
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.017 0.203
Trichomonas vaginalis cyclins, putative 0.0044 0.0128 0.9689
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0106 0.1177
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0042 0.0698
Schistosoma mansoni ets-related 0.0219 0.0802 0.256
Echinococcus granulosus tubulin alpha chain 0.0033 0.0087 0.0279
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0083 0.5221
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.0897 0.5906
Onchocerca volvulus 0.0038 0.0106 0.0701
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0954
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0082 0.0254
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0405 0.1519 0.1519
Toxoplasma gondii beta-tubulin, putative 0.0025 0.0055 0.017
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0056 0.0943
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.001 0.0108
Schistosoma mansoni alpha tubulin 0.0033 0.0087 0.0279
Giardia lamblia Hypothetical protein 0.0018 0.003 0.2207
Echinococcus granulosus cyclins 0.0018 0.003 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.001 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0004 0.0257
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0031 0.026
Echinococcus granulosus acylamino acid releasing enzyme 0.0032 0.0083 0.0266
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0125 0.1486
Brugia malayi Stress-activated protein kinase jnk-1 0.0237 0.0873 0.5748
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.1146 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.003 0.035
Trypanosoma brucei pteridine reductase 1 0.0013 0.0009 0.0065
Plasmodium vivax ataxin-2 like protein, putative 0.0055 0.017 0.203
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.012 0.0383
Echinococcus granulosus cyclin dependent kinase 0.0045 0.0132 0.0422
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0056 0.0615
Echinococcus multilocularis cyclin dependent kinase 5 0.0045 0.0132 0.0132
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0083 0.0987
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.003 0.0199
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.003 0.0326
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Echinococcus granulosus Tubulin alpha 1 chain 0.0033 0.0087 0.0279
Brugia malayi Fli-1 protein 0.0219 0.0802 0.5281
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0057 0.0377
Mycobacterium tuberculosis Conserved protein 0.0038 0.0106 0.1177
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.001 0.0108
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0031 0.026
Brugia malayi beta-lactamase family protein 0.0038 0.0106 0.0701
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0317 0.1013
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0013 0.0009 0.0128
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0082 0.0537
Trichomonas vaginalis cyclins, putative 0.0018 0.003 0.2207
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0317 0.0317
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0021 0.0042 0.0042
Chlamydia trachomatis oxoacy-ACP reductase 0.0021 0.0042 0.0402
Schistosoma mansoni tubulin subunit alpha 0.0033 0.0087 0.0279
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0056 0.0615
Echinococcus granulosus peroxisome assembly protein 26 0.0033 0.0087 0.0279
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.001 0.0108
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0136 0.0484 0.4219
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Trypanosoma cruzi cyclin, putative 0.0044 0.0128 0.1111
Echinococcus granulosus tubulin delta chain 0.0011 0.0001 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.001 0.0706
Brugia malayi beta-lactamase family protein 0.0038 0.0106 0.0701
Schistosoma mansoni cpg binding protein 0.0061 0.0195 0.0624
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.009 0.0594
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Loa Loa (eye worm) prolyl oligopeptidase 0.0032 0.0083 0.0549
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0127 0.1097
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Echinococcus multilocularis tubulin alpha chain 0.0033 0.0087 0.0087
Echinococcus multilocularis cpg binding protein 0.0061 0.0195 0.0195
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0129 0.0413
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0013 0.0009 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0106 0.1177
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.001 0.0101
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0013 0.0009 0.009
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.001 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Echinococcus multilocularis cyclin dependent kinase 0.0045 0.0132 0.0132
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0106 0.8028
Echinococcus granulosus tubulin gamma 1 chain 0.0025 0.0055 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Brugia malayi MH2 domain containing protein 0.0243 0.0897 0.5906
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Mycobacterium leprae Probable lipase LipE 0.0038 0.0106 0.3229
Trypanosoma cruzi cyclin, putative 0.0044 0.0128 0.1111
Trichomonas vaginalis cyclin B, putative 0.0018 0.003 0.2207
Plasmodium vivax tubulin gamma chain, putative 0.0025 0.0055 0.0644
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0106 0.0106
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0013 0.0009 0.0128
Echinococcus granulosus tubulin alpha chain 0.0033 0.0087 0.0279
Entamoeba histolytica hypothetical protein 0.0025 0.0057 0.2668
Trichomonas vaginalis hypothetical protein 0.0013 0.0009 0.057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Trichomonas vaginalis tubulin alpha chain, putative 0.0014 0.0014 0.0952
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0031 0.026
Loa Loa (eye worm) raf kinase 0.0221 0.0812 0.5348
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Trypanosoma brucei beta tubulin 0.0025 0.0055 0.0469
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0132 0.1146
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0056 0.0943
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0055 0.4094
Schistosoma mansoni cpg binding protein 0.0058 0.0183 0.0583
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0128
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0056 0.0615
Echinococcus granulosus cyclins 0.0018 0.003 0.0096
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0031 0.026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0106 0.0701
Brugia malayi hypothetical protein 0.0035 0.0096 0.0631
Brugia malayi glutathione reductase 0.0038 0.0105 0.069
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Entamoeba histolytica tubulin alpha-1 chain 0.0033 0.0087 0.5607
Loa Loa (eye worm) alpha-tubulin 0.0033 0.0087 0.0575
Giardia lamblia G2/mitotic-specific cyclin B 0.0044 0.0128 0.9689
Plasmodium vivax protein kinase Crk2 0.0045 0.0132 0.1572
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.003 0.035
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0107 0.0107
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0129 0.0129
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0032 0.0083 0.0266
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Loa Loa (eye worm) prolyl oligopeptidase 0.0405 0.1519 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0056 0.0943
Loa Loa (eye worm) oxidoreductase 0.0021 0.0042 0.0275
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0031 0.026
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0012 0.0005 0.0015
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Plasmodium vivax tubulin alpha chain, putative 0.0033 0.0087 0.1034
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Plasmodium falciparum protein kinase 5 0.0045 0.0132 0.1572
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0056 0.0615
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0024 0.0024
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0145 0.0462
Mycobacterium ulcerans lipase LipD 0.0038 0.0106 0.1805
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0405 0.1519 0.4848
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0044 0.0372
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0013 0.0146
Leishmania major hypothetical protein, conserved 0.0055 0.017 0.148
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.009 0.0594
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0056
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0021 0.0042 0.0356
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0156
Echinococcus granulosus tubulin alpha 1C chain 0.0033 0.0087 0.0279
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0136 0.0484 0.4219
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0132 0.0132
Echinococcus multilocularis tubulin gamma 1 chain 0.0025 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0087 0.0575
Loa Loa (eye worm) tubulin alpha 2 0.0022 0.0046 0.0304
Echinococcus granulosus tubulin epsilon chain 0.0025 0.0055 0.0175
Trypanosoma cruzi oligopeptidase b 0.0032 0.0083 0.0719
Brugia malayi Cytochrome P450 family protein 0.0102 0.0353 0.2322
Brugia malayi prolyl oligopeptidase family protein 0.0405 0.1519 1
Brugia malayi tubulin alpha-2 chain 0.0033 0.0087 0.0575
Echinococcus multilocularis peregrin 0.0035 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0025 0.0056 0.0179
Toxoplasma gondii hypothetical protein 0.0032 0.0083 0.026
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0031 0.026
Wolbachia endosymbiont of Brugia malayi (3R)-hydroxymyristoyl-ACP dehydratase 0.0227 0.0836 1
Echinococcus granulosus tubulin subunit beta 0.0025 0.0055 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0132 0.0422
Brugia malayi prolyl oligopeptidase family protein 0.0032 0.0083 0.0549
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0056 0.0943
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Echinococcus granulosus cyclin b3 0.0018 0.003 0.0096
Loa Loa (eye worm) glutathione reductase 0.0038 0.0105 0.069
Brugia malayi prolyl oligopeptidase family protein 0.0032 0.0083 0.0549
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0522 0.0522
Echinococcus multilocularis tubulin alpha 3 chain 0.0033 0.0087 0.0087
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0029 0.0029
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0068 0.0446
Echinococcus granulosus cyclins 0.0018 0.003 0.0096
Leishmania major oxidoreductase-like protein 0.0013 0.0009 0.0065
Brugia malayi Variant SH3 domain containing protein 0.0012 0.0005 0.003
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0127 0.045 0.2961
Trypanosoma brucei beta tubulin 0.0025 0.0055 0.0469
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0106 0.034
Echinococcus multilocularis Tubulin alpha 1 chain 0.0033 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Echinococcus granulosus beta tubulin 0.0025 0.0055 0.0175
Brugia malayi Smad1 0.0017 0.0024 0.0156
Loa Loa (eye worm) fli-1 protein 0.0219 0.0802 0.5281
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0844
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.001 0.0079
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.003 0.2223
Schistosoma mansoni smad 0.0017 0.0024 0.0076
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0237 0.0757
Brugia malayi prolyl oligopeptidase family protein 0.0136 0.0484 0.3187
Brugia malayi hypothetical protein 0.0104 0.036 0.2373
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0056 0.0179
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0277 0.0883
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.0545 0.3585
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.001 0.0706
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0025 0.0055 0.017
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0156
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0032 0.0083 0.0719
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.017 0.148
Echinococcus multilocularis smad 0.0017 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0106 0.092
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0012 0.0004 0.0011
Schistosoma mansoni tubulin subunit delta 0.0011 0.0001 0.0003
Echinococcus multilocularis tubulin alpha chain 0.0033 0.0087 0.0087
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0106 0.1177
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.012 0.0789
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Trypanosoma brucei beta tubulin 0.0025 0.0055 0.0469
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.036 0.2367
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.009 0.0778
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Brugia malayi Tubulin alpha chain 0.0033 0.0087 0.0575
Brugia malayi DNA-binding protein D-ETS-3 0.001 0 0.0001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0106 0.1177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Loa Loa (eye worm) hypothetical protein 0.0054 0.0169 0.111
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0145 0.0954
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0021 0.0042 0.0134
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.012 0.0383
Trypanosoma brucei oligopeptidase b 0.0032 0.0083 0.0719
Echinococcus multilocularis raf serine:threonine protein kinase 0.0223 0.0821 0.0821
Echinococcus granulosus geminin 0.034 0.1269 0.4051
Plasmodium falciparum tubulin gamma chain 0.0025 0.0055 0.0644
Echinococcus granulosus tubulin beta 1 chain 0.0025 0.0055 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Trypanosoma brucei alpha tubulin, putative 0.0014 0.0014 0.0109
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0382
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0032 0.0083 0.092
Loa Loa (eye worm) hypothetical protein 0.0062 0.0197 0.1297
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0706
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0045 0.0132 0.1146
Mycobacterium tuberculosis Probable reductase 0.0086 0.029 0.3233
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0021 0.0042 0.0455
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0106 0.034
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0111 0.1321
Schistosoma mansoni vav2 0.0012 0.0005 0.0015
Toxoplasma gondii beta-1 tubulin, putative 0.0025 0.0055 0.017
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0105 0.1159
Trichomonas vaginalis tubulin epsilon chain, putative 0.0025 0.0055 0.4094
Trypanosoma brucei prolyl endopeptidase 0.0032 0.0083 0.0719
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0021 0.0042 0.0698
Echinococcus granulosus cyclin dependent kinase 1 0.0045 0.0132 0.0422
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0013 0.0009 0.0084
Plasmodium vivax glutathione reductase, putative 0.0038 0.0105 0.1243
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.001 0.0079
Echinococcus granulosus tubulin alpha 3 chain 0.0033 0.0087 0.0279
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0105 0.069
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0048 0.0145 0.0462
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0832 0.3165 1
Echinococcus granulosus beta tubulin 0.0025 0.0055 0.0175
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.001 0.0686
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0111 0.795
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0013 0.0009 0.0229
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0055 0.0175
Brugia malayi Cytochrome P450 family protein 0.0034 0.009 0.0594
Schistosoma mansoni hypothetical protein 0.0824 0.3133 1
Schistosoma mansoni tubulin subunit alpha 0.0033 0.0087 0.0279
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0056 0.0943
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0042 0.0698
Onchocerca volvulus 0.0038 0.0106 0.0701
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Echinococcus granulosus cyclin B3 1 0.0018 0.003 0.0096
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0021 0.0042 0.0134
Leishmania major oligopeptidase b 0.0032 0.0083 0.0719
Loa Loa (eye worm) retinol dehydrogenase 12 0.0013 0.0009 0.0056
Trypanosoma brucei cdc2-related kinase 1 0.0045 0.0132 0.1146
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0009 0.0065
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0013 0.0009 0.009
Plasmodium falciparum beta-hydroxyacyl-ACP dehydratase 0.0227 0.0836 1
Loa Loa (eye worm) tubulin alpha-2 chain 0.0033 0.0087 0.0575
Trichomonas vaginalis tubulin epsilon chain, putative 0.0025 0.0055 0.4094
Toxoplasma gondii hypothetical protein 0.0014 0.0013 0.0038
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.001 0.0028
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0076
Trypanosoma brucei trypanothione reductase 0.0038 0.0105 0.0906
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0013 0.0009 0.0024
Echinococcus multilocularis tubulin subunit beta 0.0025 0.0055 0.0055
Trypanosoma brucei cdc2-related kinase 3 0.0045 0.0132 0.1146
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0029 0.0092
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0021 0.0042 0.0488
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.0897 0.5906
Onchocerca volvulus 0.0014 0.0014 0.0089
Echinococcus multilocularis cyclins 0.0018 0.003 0.003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0056 0.0481
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0056 0.0481
Toxoplasma gondii hypothetical protein 0.005 0.0151 0.0474
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0021 0.0042 0.0356
Schistosoma mansoni hypothetical protein 0.0048 0.0145 0.0462
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0031 0.0076
Schistosoma mansoni cyclin B3 0.0018 0.003 0.0096
Giardia lamblia Gamma tubulin 0.0025 0.0055 0.4094
Trichomonas vaginalis esterase, putative 0.0038 0.0106 0.8028
Schistosoma mansoni hypothetical protein 0.0048 0.0145 0.0462
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Schistosoma mansoni ap endonuclease 0.0018 0.003 0.0097
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0015 0.0049
Echinococcus granulosus tubulin alpha chain 0.0033 0.0087 0.0279
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Loa Loa (eye worm) hypothetical protein 0.0044 0.0129 0.0847
Trichomonas vaginalis tubulin gamma chain, putative 0.0025 0.0055 0.4094
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0009 0.0128
Brugia malayi Tubulin alpha-2 chain 0.0033 0.0087 0.0575
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0032 0.0083 0.6276
Trypanosoma brucei tubulin gamma chain 0.0025 0.0055 0.0469
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0031 0.0031
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0106 0.1177
Trichomonas vaginalis cyclin B, putative 0.0044 0.0128 0.9689
Loa Loa (eye worm) hypothetical protein 0.0032 0.0083 0.0549
Echinococcus granulosus N chimaerin 0.0012 0.0005 0.0015
Echinococcus granulosus tubulin alpha chain 0.0033 0.0087 0.0279
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0132 0.1146
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0132 1
Brugia malayi Tubulin beta-1 chain 0.0025 0.0055 0.0361
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0001
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0009 0.0084
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0045 0.0132 0.0415
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0084
Brugia malayi tubulin alpha chain - mouse 0.0033 0.0087 0.0575
Schistosoma mansoni tubulin subunit alpha 0.0033 0.0087 0.0279
Schistosoma mansoni cytochrome P450 0.0025 0.0056 0.0179
Echinococcus multilocularis tubulin subunit TubB 0.0033 0.0087 0.0087
Mycobacterium leprae putative cytochrome p450 0.0025 0.0056 0.1687
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0083 0.0719
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0432 0.138
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0056 0.0943
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0031 0.0203
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0015 0.0015
Toxoplasma gondii exonuclease III APE 0.0018 0.003 0.0092
Toxoplasma gondii alpha-tubulin I, putative 0.0033 0.0087 0.0273
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0054 0.0054
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Schistosoma mansoni hypothetical protein 0.0048 0.0145 0.0462
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0237 0.0873 0.0873
Loa Loa (eye worm) tubulin alpha chain 0.0033 0.0087 0.0575
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus multilocularis tubulin alpha chain 0.0033 0.0087 0.0087
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0015 0.0049
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.001 0.0108
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.012 0.0383
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0163 0.1415
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0106 0.034
Toxoplasma gondii ABC1 family protein 0.0038 0.0106 0.0333
Schistosoma mansoni hypothetical protein 0.034 0.1269 0.4051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0317 0.1013
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.001 0.0018
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0032 0.0083 0.0266
Onchocerca volvulus 0.0058 0.0183 0.1203
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.0056 0.1687
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0057 0.0491
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.003 0.0097
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.001 0.0079
Mycobacterium ulcerans hypothetical protein 0.0162 0.0585 1
Echinococcus granulosus tubulin subunit TubB 0.0033 0.0087 0.0279
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0076
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0045 0.0132 0.0422
Loa Loa (eye worm) tubulin alpha 2 0.0022 0.0046 0.0304
Toxoplasma gondii prolyl endopeptidase 0.0032 0.0083 0.026
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0009 0.0128
Toxoplasma gondii beta tubulin 0.0025 0.0055 0.017
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.001 0.0079
Leishmania major cytochrome p450-like protein 0.0025 0.0056 0.0481
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.001 0.0686
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0083 0.6276
Echinococcus granulosus tubulin alpha 0.0025 0.0055 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0706
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0031 0.0203
Giardia lamblia Cyclin A 0.0018 0.003 0.2207
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0055 0.0175
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0055 0.4094
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0029 0.019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0082 0.026
Echinococcus granulosus raf serine:threonine protein kinase 0.0223 0.0821 0.262
Echinococcus granulosus tubulin beta 4A class IVa 0.0025 0.0055 0.0175
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.003 0.035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0042 0.0698
Entamoeba histolytica cyclin, putative 0.0044 0.0128 0.9601
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.003 0.0255
Loa Loa (eye worm) hypothetical protein 0.0032 0.0083 0.0549
Echinococcus granulosus tyrosine protein kinase Lyn 0.0011 0.0001 0.0004
Trypanosoma brucei alpha tubulin 0.0033 0.0087 0.0754
Giardia lamblia Beta tubulin 0.0025 0.0055 0.4094
Toxoplasma gondii thioredoxin reductase 0.0038 0.0105 0.0328
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0031 0.026
Plasmodium falciparum glutathione reductase 0.0038 0.0105 0.1243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0087 0.6577
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0106 0.1177
Loa Loa (eye worm) CYP4Cod1 0.0034 0.009 0.0594
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0032 0.0083 0.0719
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0106 0.092
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0522 0.3435
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0021 0.0042 0.1249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Leishmania major trypanothione reductase 0.0038 0.0105 0.0906
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0009 0.0128
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Treponema pallidum NADH oxidase 0.0013 0.001 0.3085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Brugia malayi Cell division protein ftsZ 0.0011 0.0001 0.0007
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0022 0.0046 0.0304
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.001 0.0108
Echinococcus multilocularis N chimaerin 0.0012 0.0005 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0183 0.1203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus multilocularis cyclin B3 1 0.0018 0.003 0.003
Schistosoma mansoni tubulin subunit beta 0.0025 0.0055 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Echinococcus granulosus tubulin alpha 1C chain 0.0033 0.0087 0.0279
Loa Loa (eye worm) hypothetical protein 0.0032 0.0083 0.0549
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0082 0.0254
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0009 0.0084
Giardia lamblia Beta tubulin 0.0025 0.0055 0.4094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Plasmodium falciparum tubulin epsilon chain, putative 0.0025 0.0055 0.0644
Echinococcus multilocularis Tubulin alpha 1 chain 0.0033 0.0087 0.0087
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0055 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0288
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.029 0.3233
Echinococcus multilocularis tubulin alpha 3 chain 0.0033 0.0087 0.0087
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0056 0.0943
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0701
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0056 0.0943
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0031 0.026
Schistosoma mansoni alpha tubulin 0.0033 0.0087 0.0279
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0032 0.0083 0.1411
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0056 0.0943
Brugia malayi RhoGAP domain containing protein 0.0012 0.0005 0.003
Brugia malayi beta-lactamase 0.0038 0.0106 0.0701
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0056 0.0943
Echinococcus multilocularis hypothetical protein 0.0033 0.0087 0.0087
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0055 0.0055
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0033 0.0087 0.6577
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0056 0.0943
Brugia malayi alpha-tubulin 0.0033 0.0087 0.0575
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0018 0.003 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0056 0.0615
Plasmodium falciparum tubulin beta chain 0.0025 0.0055 0.0644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0031 0.0098
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0106 0.3229
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0018 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0045 0.0132 0.0871
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0031 0.0076
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0031 0.026
Leishmania major pteridine reductase 1 0.0013 0.0009 0.0065
Echinococcus multilocularis tubulin alpha 1C chain 0.0033 0.0087 0.0087
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0056 0.0943
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0013 0.0009 0.0065
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0009 0.0128
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0106 0.1805
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0055 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Schistosoma mansoni alpha tubulin 0.0033 0.0087 0.0279
Echinococcus multilocularis 0.0025 0.0056 0.0056
Leishmania major gamma-tubulin 0.0025 0.0055 0.0469
Loa Loa (eye worm) BEN-1 protein 0.0025 0.0055 0.0361
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0045 0.0132 0.1146
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.001 0.0154
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0057 0.0183
Plasmodium vivax tubulin epsilon chain, putative 0.0025 0.0055 0.0644
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0024 0.0024
Brugia malayi Cyclin, N-terminal domain containing protein 0.0044 0.0128 0.0844
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0022 0.0046 0.3435
Trypanosoma brucei mitotic cyclin 6 0.0044 0.0128 0.1111
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0021 0.0042 0.0488
Loa Loa (eye worm) tubulin beta-1 chain 0.0025 0.0055 0.0361
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0056 0.0943
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0308 0.1146 1
Plasmodium vivax tubulin alpha chain, putative 0.0033 0.0087 0.1034
Brugia malayi Cytochrome P450 family protein 0.0034 0.009 0.0594
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0056 0.0943
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.029 0.3233
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.0545 0.3585
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0873 0.2787
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0156
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0021 0.0042 0.0356
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0024 0.0076
Brugia malayi transcription factor E74 isoform 0.001 0 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0211 0.139
Loa Loa (eye worm) hypothetical protein 0.0032 0.0082 0.0537
Echinococcus multilocularis dnaJ subfamily B 0.0824 0.3133 0.3133
Trichomonas vaginalis tubulin, putative 0.0014 0.0014 0.0952
Brugia malayi PHD-finger family protein 0.0014 0.0012 0.0081
Entamoeba histolytica prolyl oligopeptidase family protein 0.0032 0.0083 0.5221
Plasmodium falciparum cyclin 0.0018 0.003 0.0347
Loa Loa (eye worm) Smad1 0.0017 0.0024 0.0156
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0012 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0031 0.0098
Brugia malayi PHD-finger family protein 0.0032 0.0082 0.0537
Trichomonas vaginalis cyclins, putative 0.0044 0.0128 0.9689
Echinococcus granulosus cyclin dependent kinase 5 0.0045 0.0132 0.0422
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0106 0.092
Trypanosoma cruzi epsilon tubulin, putative 0.0025 0.0055 0.0469
Plasmodium falciparum thioredoxin reductase 0.0038 0.0105 0.1243
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0056 0.0943
Echinococcus multilocularis tubulin epsilon chain 0.0025 0.0055 0.0055
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.001 0.0686
Echinococcus granulosus smad 0.0017 0.0024 0.0076
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0021 0.0042 0.0356
Trichomonas vaginalis cyclin D, putative 0.0018 0.003 0.2207
Echinococcus multilocularis tubulin alpha chain 0.0033 0.0087 0.0087
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0055 0.0175
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0032 0.0083 0.0719
Leishmania major beta tubulin 0.0025 0.0055 0.0469
Trypanosoma cruzi beta tubulin, putative 0.0025 0.0055 0.0469
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0031 0.0094
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.003 0.2207
Leishmania major alpha tubulin 0.0033 0.0087 0.0754
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0001
Loa Loa (eye worm) tubulin alpha-3 chain 0.0019 0.0034 0.0222
Schistosoma mansoni cpg binding protein 0.0061 0.0195 0.0624
Loa Loa (eye worm) tubulin gamma chain 0.0025 0.0055 0.0361
Trichomonas vaginalis cyclin B3, putative 0.0018 0.003 0.2207
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0009 0.0128
Schistosoma mansoni hypothetical protein 0.0032 0.0082 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0057 0.4286
Trypanosoma brucei cytochrome P450, putative 0.0034 0.009 0.0778
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0132 0.1146
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0042 0.0698
Trypanosoma brucei PAB1-binding protein , putative 0.0055 0.017 0.148
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0056 0.0615
Loa Loa (eye worm) hypothetical protein 0.0152 0.0545 0.3585
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0056 0.0615
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0055 0.0055
Loa Loa (eye worm) tubulin alpha chain 0.0033 0.0087 0.0575
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.029 0.8869
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0106 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0031 0.2266
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0056 0.0615
Trichomonas vaginalis cyclin B, putative 0.0044 0.0128 0.9689
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.003 0.2223

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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