Detailed information for compound 1323594

Basic information

Technical information
  • TDR Targets ID: 1323594
  • Name: propan-2-yl 6-amino-5-cyano-4-[5-(4-fluorophe nyl)pyridin-3-yl]-2-methyl-4H-pyran-3-carboxy late
  • MW: 393.411 | Formula: C22H20FN3O3
  • H donors: 1 H acceptors: 3 LogP: 3.57 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC1=C(N)OC(=C(C1c1cncc(c1)c1ccc(cc1)F)C(=O)OC(C)C)C
  • InChi: 1S/C22H20FN3O3/c1-12(2)28-22(27)19-13(3)29-21(25)18(9-24)20(19)16-8-15(10-26-11-16)14-4-6-17(23)7-5-14/h4-8,10-12,20H,25H2,1-3H3
  • InChiKey: BODRXYMQLVJWQN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • isopropyl 6-amino-5-cyano-4-[5-(4-fluorophenyl)-3-pyridyl]-2-methyl-4H-pyran-3-carboxylate
  • 6-amino-5-cyano-4-[5-(4-fluorophenyl)-3-pyridyl]-2-methyl-4H-pyran-3-carboxylic acid isopropyl ester
  • SMR000228411
  • isopropyl 6-amino-5-cyano-4-[5-(4-fluorophenyl)-3-pyridinyl]-2-methyl-4H-pyran-3-carboxylate
  • AM-807/42003997
  • MLS000698250

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cyclin B, putative 0.0081 0.0346 0.1068
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0121 0.0729 0.0764
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0214 0.1621 0.1956
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1013 0.9251 1
Trypanosoma brucei protein kinase, putative 0.0137 0.0879 0.3621
Loa Loa (eye worm) hypothetical protein 0.0128 0.0799 0.084
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0155 0.1052 0.3012
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0057 0.0117 0.0229
Toxoplasma gondii casein kinase I 0.0115 0.0673 0.29
Echinococcus granulosus serine:threonine protein kinase 3 0.0275 0.2198 0.2183
Loa Loa (eye worm) hypothetical protein 0.0145 0.0961 0.1015
Trypanosoma brucei casein kinase I, isoform 2 0.0115 0.0673 0.2692
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.0475 0.1355
Loa Loa (eye worm) hypothetical protein 0.0072 0.0264 0.026
Entamoeba histolytica protein kinase, putative 0.0171 0.1207 0.3456
Giardia lamblia Kinase, CMGC CDK 0.0126 0.0778 0.2441
Entamoeba histolytica casein kinase 1, putative 0.0115 0.0673 0.1924
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0644 0.5731 0.6185
Loa Loa (eye worm) hypothetical protein 0.0096 0.0494 0.0509
Echinococcus multilocularis expressed protein 0.0087 0.041 0.0495
Brugia malayi Hr1 repeat family protein 0.0307 0.251 0.2688
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0115 0.0673 0.3377
Trypanosoma brucei SNF1-related protein kinases, putative 0.0094 0.0475 0.1797
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0091 0.044 0.0531
Loa Loa (eye worm) TK protein kinase 0.0171 0.1207 0.1282
Trichomonas vaginalis STE family protein kinase 0.0145 0.0956 0.3163
Loa Loa (eye worm) hypothetical protein 0.0072 0.0264 0.026
Brugia malayi STAT protein, DNA binding domain containing protein 0.006 0.0146 0.0125
Loa Loa (eye worm) hypothetical protein 0.0096 0.0494 0.0509
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0985 0.0967
Trichomonas vaginalis glutaminase, putative 0.0309 0.2526 0.8552
Echinococcus granulosus cpg binding protein 0.0099 0.0525 0.0505
Plasmodium falciparum serine/threonine protein kinase 0.0087 0.041 0.3147
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0248 0.1944 0.208
Echinococcus multilocularis 0.013 0.0817 0.0986
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0117 0.0078
Plasmodium falciparum glycogen synthase kinase 3 0.0137 0.0879 0.7574
Brugia malayi ephrin receptor 1 precursor 0.0077 0.031 0.0303
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0035 0.0014
Schistosoma mansoni protein kinase 0.0465 0.4021 0.5039
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0265 0.2108 0.2092
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0104 0.0571 0.0689
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.2902 0.3616
Toxoplasma gondii AGC kinase 0.012 0.0718 0.3105
Echinococcus multilocularis hypothetical protein 0.011 0.0623 0.0752
Echinococcus granulosus dual specificity 0.0091 0.044 0.042
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Loa Loa (eye worm) hypothetical protein 0.0061 0.0156 0.0142
Trypanosoma brucei polo-like protein kinase 0.0237 0.1843 0.7971
Trypanosoma cruzi casein kinase, putative 0.0115 0.0673 0.3377
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0055 0.0104 0.0239
Entamoeba histolytica PH domain containing protein kinase, putative 0.0126 0.0775 0.2216
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0074 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Loa Loa (eye worm) protein kinase domain-containing protein 0.0228 0.175 0.187
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0167 0.1175 0.1418
Loa Loa (eye worm) hypothetical protein 0.0072 0.0262 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0393 0.0429
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0085 0.0389 0.1607
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0673 0.0784
Loa Loa (eye worm) hypothetical protein 0.0121 0.0729 0.0764
Giardia lamblia Kinase, STE STE20 0.0091 0.044 0.1266
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0137 0.0879 0.4543
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.0264 0.0253
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0155 0.1052 0.127
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Echinococcus granulosus tyrosine protein kinase 0.0303 0.2468 0.2453
Schistosoma mansoni microtubule-associated protein tau 0.0747 0.6718 0.8465
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.1842 0.227
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0699
Loa Loa (eye worm) hypothetical protein 0.0317 0.2604 0.2796
Giardia lamblia Kinase, CDC7 0.0095 0.0479 0.14
Echinococcus multilocularis serine threonine protein kinase 0.0212 0.1596 0.1926
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.012 0.0718 0.3631
Brugia malayi Pleckstrin Homology Domain 0.0059 0.014 0.0118
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0146 0.0176
Echinococcus granulosus transient receptor potential ion channel A 0.0414 0.3532 0.3519
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0163 0.1136 0.4781
Entamoeba histolytica protein kinase, putative 0.0284 0.2293 0.6572
Loa Loa (eye worm) hypothetical protein 0.006 0.0152 0.0139
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.012 0.0718 0.3631
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0175 0.1244 0.1226
Echinococcus granulosus tyrosine protein kinase Src64B 0.0265 0.2108 0.2092
Entamoeba histolytica protein kinase, putative 0.0278 0.2236 0.641
Echinococcus granulosus twitchin 0.0111 0.0634 0.0615
Loa Loa (eye worm) hypothetical protein 0.0269 0.2146 0.2299
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.013 0.0813 0.3322
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0593 0.0715
Echinococcus multilocularis cyclin dependent kinase 1 0.0126 0.0778 0.0938
Leishmania major protein kinase, putative 0.0107 0.0593 0.2921
Entamoeba histolytica protein kinase, putative 0.0091 0.044 0.1254
Loa Loa (eye worm) STAT protein 0.006 0.0146 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.1244 0.151
Echinococcus multilocularis geminin 0.0205 0.153 0.1846
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Echinococcus multilocularis ephrin type A receptor 4 A 0.0113 0.0659 0.0795
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0237 0.1842 0.2223
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0163 0.1131 0.12
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0429 0.3673 0.366
Loa Loa (eye worm) acetyltransferase 0.0164 0.1139 0.1208
Trypanosoma cruzi Protein kinase B 0.015 0.1011 0.5292
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0673 0.0812
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Echinococcus multilocularis myosin iiia 0.0089 0.0426 0.0514
Echinococcus multilocularis SH2 motif 0.006 0.0146 0.0176
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0165 0.1152 0.1215
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0231 0.1778 0.1762
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Schistosoma mansoni cyclin B 0.0081 0.0346 0.0368
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.012 0.0718 0.3631
Entamoeba histolytica protein kinase, putative 0.0086 0.0393 0.1121
Onchocerca volvulus 0.0104 0.0571 0.1302
Leishmania major protein kinase A catalytic subunit 0.012 0.0718 0.3631
Giardia lamblia Kinase, AGC PKA 0.012 0.0718 0.2234
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0188 0.1374 0.1658
Plasmodium vivax serine/threonine kinase-1, putative 0.0163 0.1136 1
Echinococcus multilocularis dnaJ subfamily B 0.0874 0.7925 0.9563
Entamoeba histolytica serine/threonine protein kinase, putative 0.0053 0.0077 0.0212
Plasmodium vivax calcium-dependent protein kinase, putative 0.0107 0.0593 0.5066
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Brugia malayi Protein kinase domain containing protein 0.0175 0.1244 0.1315
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0094 0.0475 0.2254
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0216 0.164 0.1979
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Echinococcus granulosus STE20 serine:threonine protein kinase 0.053 0.4644 0.4633
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.218 0.2699
Echinococcus multilocularis SH2 motif 0.006 0.0146 0.0176
Trypanosoma brucei Casein kinase II 0.0106 0.0585 0.2295
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0417 0.1311
Schistosoma mansoni ste20-related kinase 0.0219 0.1666 0.2046
Onchocerca volvulus 0.0348 0.2902 0.6951
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0258 0.2041 0.2463
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1052 0.3493
Schistosoma mansoni hypothetical protein 0.006 0.0146 0.0115
Onchocerca volvulus 0.0336 0.2789 0.6678
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0089 0.0426 0.1577
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Brugia malayi CXXC zinc finger family protein 0.0094 0.0473 0.048
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.006 0.0146 0.0132
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0144 0.0955 0.0936
Entamoeba histolytica casein kinase, putative 0.0115 0.0673 0.1924
Schistosoma mansoni ephrin receptor 0.0113 0.0659 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1778 0.2189
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.006 0.0146 0.0126
Plasmodium vivax protein kinase Crk2 0.0126 0.0778 0.6744
Onchocerca volvulus 0.009 0.0435 0.0972
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.1193 0.6318
Schistosoma mansoni protein kinase 0.0106 0.0585 0.0673
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0319 0.0908
Loa Loa (eye worm) hypothetical protein 0.0072 0.0264 0.026
Brugia malayi N-terminal motif family protein 0.0223 0.1708 0.1819
Echinococcus granulosus titin 0.0062 0.0167 0.0147
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0074 0.0089
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0216 0.164 0.1745
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0718 0.0745
Echinococcus granulosus dual specificity 0.013 0.0813 0.0794
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.1193 0.1439
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0126 0.0778 0.0759
Onchocerca volvulus 0.0068 0.0223 0.0458
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.049 0.4254 0.5133
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0431 0.3694 0.3681
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Schistosoma mansoni hypothetical protein 0.006 0.0146 0.0115
Schistosoma mansoni vav2 0.0119 0.0711 0.0833
Schistosoma mansoni cpg binding protein 0.0099 0.0525 0.0596
Entamoeba histolytica protein kinase, putative 0.0087 0.041 0.1169
Schistosoma mansoni vesicular amine transporter 0.0075 0.0289 0.0296
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1052 0.1114
Loa Loa (eye worm) hypothetical protein 0.0069 0.0234 0.0227
Echinococcus multilocularis myotubularin protein 13 0.0059 0.014 0.0169
Schistosoma mansoni tyrosine kinase 0.0139 0.09 0.1073
Loa Loa (eye worm) hypothetical protein 0.0223 0.1708 0.1825
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0168 0.1182 0.1248
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0593 0.0715
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0102 0.0124
Schistosoma mansoni tyrosine kinase 0.0334 0.2769 0.3448
Brugia malayi Variant SH3 domain containing protein 0.0113 0.0655 0.0676
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0091 0.044 0.2054
Schistosoma mansoni tyrosine kinase 0.0151 0.102 0.1225
Echinococcus granulosus protein kinase C gamma type 0.0212 0.1596 0.1579
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0237 0.1843 0.1971
Trichomonas vaginalis STE family protein kinase 0.0053 0.0077 0.0144
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0102 0.0082
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0106 0.0585 0.0608
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0778 0.2551
Echinococcus multilocularis 0.0163 0.1131 0.1365
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0088 0.0417 0.1924
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0216 0.164 0.1752
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.1193 0.1439
Schistosoma mansoni Neurotrimin precursor (hNT) 0.006 0.0152 0.0123
Brugia malayi Protein kinase domain containing protein 0.0121 0.0729 0.0757
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0126 0.0778 0.0816
Loa Loa (eye worm) AGC/NDR protein kinase 0.0167 0.1175 0.1247
Echinococcus granulosus SH2 motif 0.006 0.0146 0.0126
Schistosoma mansoni mixed-lineage leukemia protein mll 0.02 0.1481 0.1811
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0062 0.0167 0.0155
Giardia lamblia Kinase, AGC PKA 0.0144 0.0955 0.3059
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0117 0.0078
Schistosoma mansoni serine/threonine-protein kinase 0.015 0.1011 0.1214
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0074 0.0284 0.0342
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0146 0.0115
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.012 0.0725 0.0706
Schistosoma mansoni cell adhesion molecule 0.0084 0.0374 0.0404
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0283 0.2275 0.2439
Loa Loa (eye worm) hypothetical protein 0.0089 0.0424 0.0433
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0057 0.0117 0.0093
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.2108 0.2092
Echinococcus multilocularis SH2 motif 0.006 0.0146 0.0176
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0102 0.0082
Leishmania major casein kinase, putative 0.0115 0.0673 0.3377
Echinococcus multilocularis serine:threonine protein kinase 0.0121 0.0729 0.088
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0061 0.0161 0.0434
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0198 0.1467 0.177
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0107 0.0593 0.5066
Onchocerca volvulus 0.0115 0.0673 0.1549
Schistosoma mansoni protein kinase 0.0078 0.0319 0.0335
Echinococcus multilocularis casein kinase I delta 0.0115 0.0673 0.0812
Schistosoma mansoni protein kinase 0.0078 0.0319 0.0335
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0113 0.0655 0.0636
Schistosoma mansoni GTPase activating protein 0.006 0.0146 0.0115
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0048 0.0031 0.0007
Echinococcus multilocularis dual specificity 0.013 0.0813 0.0981
Brugia malayi Fibronectin type III domain containing protein 0.0072 0.0264 0.0253
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0231 0.1778 0.2146
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0778 0.2551
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0077 0.0144
Brugia malayi protein kinase C3,putative 0.0176 0.1256 0.1329
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0074 0.0284 0.0264
Plasmodium falciparum calcium-dependent protein kinase 4 0.0107 0.0593 0.487
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0047 0.002 0.0024
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0122 0.0739 0.0892
Brugia malayi Protein kinase domain containing protein 0.0104 0.0571 0.0586
Loa Loa (eye worm) protein-tyrosine phosphatase 0.006 0.0146 0.0132
Echinococcus granulosus insulin receptor 0.0478 0.4143 0.4131
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.012 0.0718 0.3631
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0055 0.0104 0.0239
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0175 0.1244 0.1322
Brugia malayi hypothetical protein 0.0061 0.0156 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0718 0.0842
Entamoeba histolytica protein kinase, putative 0.0155 0.1052 0.3012
Loa Loa (eye worm) CAMK protein kinase 0.0062 0.0167 0.0155
Brugia malayi Protein kinase domain containing protein 0.0126 0.0778 0.081
Echinococcus multilocularis tyrosine protein kinase HCK 0.0171 0.1207 0.1456
Schistosoma mansoni protein kinase 0.0091 0.044 0.0488
Echinococcus granulosus mitogen activated protein kinase 11 0.0169 0.1193 0.1175
Schistosoma mansoni protein kinase 0.0155 0.1052 0.1266
Loa Loa (eye worm) camk/dcamkl protein kinase 0.016 0.1107 0.1174
Loa Loa (eye worm) hypothetical protein 0.0213 0.161 0.1719
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0393 0.1231
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0431 0.3694 0.4458
Brugia malayi Cyclin, N-terminal domain containing protein 0.0081 0.0346 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Echinococcus granulosus protein kinase c epsilon type 0.0222 0.1697 0.168
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1778 0.2189
Echinococcus granulosus cGMP dependent protein kinase 0.0148 0.0985 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0652 0.0757
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0699
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Brugia malayi MAP kinase sur-1 0.0088 0.0417 0.0418
Schistosoma mansoni tensin 0.006 0.0146 0.0115
Echinococcus granulosus tyrosine protein kinase shark 0.0334 0.2769 0.2754
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0074 0.0284 0.0343
Trypanosoma cruzi cdc2-related kinase 3 0.0126 0.0778 0.3968
Brugia malayi Kinase associated domain 1 family protein 0.011 0.0623 0.0642
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0265 0.2108 0.2543
Brugia malayi Protein kinase domain containing protein 0.0104 0.0571 0.0586
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0156 0.1066 0.3542
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0232 0.1788 0.1912
Trichomonas vaginalis STE family protein kinase 0.0067 0.0217 0.0625
Toxoplasma gondii NEK kinase 0.0053 0.0077 0.0191
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0107 0.0593 0.0574
Echinococcus granulosus casein kinase i 0.0115 0.0673 0.0654
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0061 0.0162 0.0195
Schistosoma mansoni tyrosine kinase 0.0265 0.2108 0.2607
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0137 0.0879 0.0927
Loa Loa (eye worm) hypothetical protein 0.0094 0.0475 0.0488
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0107 0.0593 0.0574
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0146 0.0132
Echinococcus granulosus tyrosine protein kinase Src42A 0.0188 0.1374 0.1356
Brugia malayi STE20-like kinase MST 0.0275 0.2198 0.2351
Loa Loa (eye worm) hypothetical protein 0.0061 0.0156 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Loa Loa (eye worm) hypothetical protein 0.0113 0.0653 0.0681
Brugia malayi serine/threonine-protein kinase plk-2 0.0237 0.1843 0.1965
Echinococcus granulosus serine/threonine protein kinase 0.015 0.1011 0.0993
Loa Loa (eye worm) casein kinase 0.0194 0.143 0.1524
Onchocerca volvulus 0.006 0.0146 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0512 0.4465 0.5602
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0187 0.1364 0.1452
Giardia lamblia Kinase, STE STE20 0.0089 0.0426 0.1217
Brugia malayi serine/threonine-protein kinase PAK 7 0.0248 0.1944 0.2074
Loa Loa (eye worm) hypothetical protein 0.0224 0.1717 0.1835
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0061 0.0162 0.0142
Schistosoma mansoni tyrosine kinase 0.0653 0.5816 0.732
Entamoeba histolytica protein kinase, putative 0.0091 0.044 0.1255
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0107 0.0593 0.2328
Brugia malayi Sex muscle abnormal protein 5 0.0094 0.0475 0.0482
Brugia malayi hypothetical protein 0.012 0.0725 0.0752
Plasmodium falciparum protein kinase, putative 0.0078 0.0319 0.2287
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0126 0.0778 0.0816
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0167 0.1175 0.1157
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.013 0.0813 0.0855
Onchocerca volvulus Tyrosine kinase homolog 0.0398 0.3376 0.8101
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0053 0.0077 0.0381
Echinococcus granulosus cyclin dependent kinase 5 0.0126 0.0778 0.0759
Giardia lamblia Kinase, CK1 Casein kinase 0.0115 0.0673 0.2078
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0111 0.0635 0.0767
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0163 0.1136 0.5998
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0856 0.2818
Plasmodium falciparum protein serine/threonine kinase-1 0.0163 0.1136 1
Brugia malayi Protein kinase domain containing protein 0.0284 0.2293 0.2453
Echinococcus granulosus expressed conserved protein 0.006 0.0146 0.0126
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0122 0.0739 0.0721
Echinococcus granulosus suppressor of cytokine signaling 6 0.006 0.0146 0.0126
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0725 0.3669
Schistosoma mansoni rap gtpase-activating protein 0.012 0.0725 0.085
Schistosoma mansoni protein kinase C 0.0055 0.0096 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0985 0.1181
Echinococcus granulosus cyclin dependent kinase 1 0.0126 0.0778 0.0759
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0216 0.164 0.1623
Trichomonas vaginalis cyclin B, putative 0.0081 0.0346 0.1068
Loa Loa (eye worm) AGC/PKN protein kinase 0.0307 0.251 0.2694
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0107 0.0593 0.5066
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.006 0.0146 0.0115
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0282 0.2273 0.2258
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Echinococcus granulosus SH2 motif 0.006 0.0146 0.0126
Brugia malayi diacylglycerol kinase 0.0053 0.0083 0.0057
Echinococcus multilocularis protein kinase c epsilon type 0.0222 0.1697 0.2047
Loa Loa (eye worm) TK/ABL protein kinase 0.0104 0.0571 0.0593
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0091 0.044 0.0421
Echinococcus granulosus fibroblast growth factor receptor 4 0.0151 0.102 0.1002
Schistosoma mansoni growth factor receptor-bound protein 0.0096 0.0496 0.0559
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0265 0.2108 0.2543
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0148 0.0985 0.4318
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Entamoeba histolytica protein kinase, putative 0.0067 0.0217 0.0614
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.013 0.0813 0.4168
Echinococcus multilocularis protein kinase shaggy 0.0137 0.0879 0.1061
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0155 0.1052 0.3012
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0091 0.044 0.2054
Brugia malayi Protein kinase domain containing protein 0.0163 0.1136 0.1199
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0378 0.3184 0.342
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1175 0.1422
Echinococcus multilocularis protein kinase c iota type 0.031 0.2537 0.3062
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0214 0.1621 0.1731
Echinococcus granulosus cyclin dependent kinase 0.0126 0.0778 0.0759
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.1052 0.1266
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0167 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0813 0.0962
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0465 0.4021 0.4009
Giardia lamblia Kinase, CMGC SRPK 0.0087 0.041 0.1161
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0107 0.0593 0.5066
Echinococcus multilocularis SHC transforming protein 3 0.006 0.0146 0.0176
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0673 0.2192
Schistosoma mansoni nephrin 0.0089 0.0426 0.047
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0086 0.0393 0.0374
Echinococcus multilocularis Diacylglycerol kinase theta 0.0053 0.0083 0.0101
Schistosoma mansoni tyrosine kinase 0.0384 0.3248 0.4056
Onchocerca volvulus 0.006 0.0146 0.0271
Brugia malayi RhoGAP domain containing protein 0.0113 0.0655 0.0676
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0057 0.0117 0.0101
Onchocerca volvulus 0.0104 0.0571 0.1302
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0074 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1175 0.1422
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0113 0.0655 0.0683
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0088 0.0417 0.0425
Toxoplasma gondii AGC kinase 0.0278 0.2236 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0096 0.0078
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.0739 0.2419
Giardia lamblia G2/mitotic-specific cyclin B 0.0081 0.0346 0.0937
Loa Loa (eye worm) hypothetical protein 0.0149 0.1003 0.1061
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0465 0.4021 0.4852
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.2662 0.3312
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0078 0.0319 0.1292
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Giardia lamblia Kinase, CMGC GSK 0.0137 0.0879 0.2795
Schistosoma mansoni tyrosine kinase 0.0139 0.09 0.1073
Loa Loa (eye worm) CXXC zinc finger family protein 0.0094 0.0473 0.0487
Onchocerca volvulus 0.0104 0.0571 0.1302
Brugia malayi RNA, U transporter 1 0.0093 0.046 0.0465
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0673 0.0703
Schistosoma mansoni transient receptor potential channel 4 0.0428 0.3668 0.4591
Giardia lamblia Kinase, CMGC CDK 0.0126 0.0778 0.2441
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0139 0.09 0.1073
Onchocerca volvulus 0.0149 0.1003 0.2349
Brugia malayi Protein kinase domain containing protein 0.0393 0.333 0.3578
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Echinococcus granulosus GPCR family 2 0.0052 0.0074 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.3612 0.452
Brugia malayi Cam kinase protein 1 0.0107 0.0593 0.0609
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0879 0.2899
Schistosoma mansoni kinase 0.0137 0.0881 0.1049
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0107 0.0593 0.2535
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0167 0.0148
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.012 0.0718 0.2894
Schistosoma mansoni adapter molecule crk 0.0094 0.0475 0.0533
Schistosoma mansoni nck2/grb4 0.0094 0.0475 0.0533
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0237 0.1842 0.197
Loa Loa (eye worm) hypothetical protein 0.0165 0.1152 0.1222
Onchocerca volvulus 0.0137 0.0879 0.2048
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0943 0.1127
Brugia malayi Furin-like cysteine rich region family protein 0.0653 0.5816 0.6275
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Schistosoma mansoni rac gtpase activating protein 0.0053 0.0083 0.0035
Brugia malayi Protein kinase domain containing protein 0.0199 0.1478 0.1569
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Loa Loa (eye worm) hypothetical protein 0.0387 0.3269 0.3517
Brugia malayi Protein kinase domain containing protein 0.013 0.0813 0.0848
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Schistosoma mansoni hypothetical protein 0.011 0.0623 0.0721
Plasmodium falciparum calcium-dependent protein kinase 3 0.0107 0.0593 0.487
Entamoeba histolytica protein kinase, putative 0.0284 0.2293 0.6572
Giardia lamblia Kinase, CMGC CK2 0.0106 0.0585 0.1771
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.1843 0.2271
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Echinococcus multilocularis L aminoadipate semialdehyde 0.009 0.0435 0.0525
Loa Loa (eye worm) hypothetical protein 0.0644 0.5731 0.6185
Brugia malayi cytokine inducible SH2-containing protein 5 0.006 0.0146 0.0125
Echinococcus granulosus transient receptor potential gamma protein 0.0428 0.3668 0.3656
Entamoeba histolytica cell division protein kinase 2, putative 0.0126 0.0778 0.2224
Toxoplasma gondii histone lysine methyltransferase SET1 0.0182 0.1316 0.582
Loa Loa (eye worm) hypothetical protein 0.006 0.0152 0.0139
Loa Loa (eye worm) hypothetical protein 0.0149 0.1003 0.1061
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0091 0.044 0.0421
Onchocerca volvulus 0.012 0.0725 0.1674
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0088 0.0417 0.1924
Echinococcus granulosus serine:threonine protein kinase mig 15 0.025 0.1962 0.1946
Echinococcus granulosus epidermal growth factor receptor 0.0653 0.5816 0.5808
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.2947 0.8451
Schistosoma mansoni tyrosine kinase 0.025 0.1965 0.2426
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0055 0.0096 0.0076
Schistosoma mansoni tyrosine kinase 0.0429 0.3673 0.4597
Echinococcus granulosus titin 0.0062 0.0167 0.0147
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Echinococcus granulosus Rac GTPase activating protein 1 0.0053 0.0083 0.0063
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0111 0.0635 0.0616
Echinococcus granulosus serine:threonine kinase SAD 1 0.0094 0.0475 0.0456
Schistosoma mansoni protein kinase 0.0163 0.1131 0.1366
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0151 0.102 0.1231
Schistosoma mansoni hypothetical protein 0.0113 0.0653 0.0758
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0072 0.0262 0.0243
Echinococcus multilocularis tensin 0.006 0.0146 0.0176
Onchocerca volvulus 0.0095 0.0479 0.1078
Schistosoma mansoni tyrosine kinase 0.0384 0.3248 0.4056
Schistosoma mansoni tensin 0.006 0.0146 0.0115
Trypanosoma cruzi polo-like protein kinase, putative 0.0237 0.1843 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0346 0.0348
Echinococcus granulosus casein kinase I alpha 0.0115 0.0673 0.0654
Plasmodium vivax unspecified product 0.0106 0.0585 0.4998
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.251 0.3118
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0163 0.1136 0.4781
Trypanosoma cruzi casein kinase II, putative 0.0106 0.0585 0.2879
Brugia malayi Protein kinase domain containing protein 0.0644 0.5731 0.6182
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Echinococcus granulosus unc 13 munc13 0.0055 0.0096 0.0076
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0074 0.0284 0.0264
Brugia malayi putative serine/threonine kinase SADA gamma 0.0094 0.0475 0.0481
Brugia malayi Protein kinase domain containing protein 0.0104 0.0571 0.0586
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0137 0.0879 0.3836
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1052 0.3493
Echinococcus multilocularis tyrosine protein kinase Blk 0.0231 0.1778 0.2146
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus granulosus snurportin 1 0.0348 0.2898 0.2883
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0144 0.0955 0.1152
Echinococcus multilocularis SH2 domain containing protein 7 0.006 0.0146 0.0176
Echinococcus granulosus casein kinase I delta 0.0115 0.0673 0.0654
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0259 0.2052 0.2476
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Echinococcus granulosus SHC transforming protein 3 0.006 0.0146 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.2105 0.2604
Schistosoma mansoni atypical protein kinase C 0.0317 0.26 0.3233
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0223 0.1708 0.4058
Schistosoma mansoni protein kinase 0.0465 0.4021 0.5039
Brugia malayi Fes/CIP4 homology domain containing protein 0.0116 0.0685 0.0709
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0151 0.102 0.1002
Echinococcus granulosus tyrosine protein kinase Srms 0.0543 0.4768 0.4757
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0155 0.1052 0.9238
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0053 0.0083 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0778 0.0917
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.013 0.0813 0.4168
Echinococcus granulosus dnaJ subfamily B 0.0874 0.7925 0.7921
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0115 0.0673 0.0703
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0113 0.0655 0.0761
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0094 0.0475 0.2254
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0359 0.3003 0.3229
Schistosoma mansoni protein kinase 0.0115 0.0673 0.0784
Loa Loa (eye worm) AGC/PKA protein kinase 0.012 0.0718 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0195 0.1442 0.4832
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0094 0.0475 0.2254
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.019 0.1386 0.1475
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0423 0.3612 0.3889
Echinococcus granulosus Protein kinase C brain isozyme 0.0265 0.2105 0.2089
Brugia malayi p70 ribosomal S6 kinase beta 0.0278 0.2236 0.2391
Plasmodium falciparum serine/threonine protein kinase, putative 0.0155 0.1052 0.9208
Echinococcus multilocularis PAK box P21 Rho binding 0.0067 0.0217 0.0262
Schistosoma mansoni tensin-related 0.006 0.0146 0.0115
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Brugia malayi Casein kinase II, alpha chain 0.0106 0.0585 0.0601
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0198 0.1467 0.145
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0718 0.6204
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Brugia malayi Protein kinase domain containing protein 0.0104 0.0571 0.0586
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0091 0.044 0.1839
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0359 0.3003 0.3224
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0163 0.1136 0.5004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0319 0.1372
Schistosoma mansoni tyrosine kinase 0.0478 0.4143 0.5193
Brugia malayi Protein kinase domain 0.0091 0.044 0.0444
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0866
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Echinococcus granulosus L aminoadipate semialdehyde 0.009 0.0435 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.2052 0.2537
Loa Loa (eye worm) glutaminase 2 0.0309 0.2526 0.2711
Echinococcus granulosus dual specificity 0.0091 0.044 0.042
Loa Loa (eye worm) hypothetical protein 0.0094 0.0475 0.0489
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0113 0.0655 0.0761
Echinococcus granulosus protein kinase 0.0163 0.1131 0.1113
Echinococcus granulosus serine:threonine protein kinase N2 0.0307 0.251 0.2495
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0146 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0265 0.2108 0.2543
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Brugia malayi Protein kinase domain containing protein 0.0086 0.0393 0.0393
Echinococcus multilocularis NCK adaptor protein 0.0096 0.0496 0.0598
Trichomonas vaginalis cyclins, putative 0.0081 0.0346 0.1068
Brugia malayi Tyrosine-protein kinase abl-1 0.0139 0.09 0.0943
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.1139 0.1375
Echinococcus granulosus mitogen activated protein kinase 14 0.0169 0.1193 0.1175
Trichomonas vaginalis cyclins, putative 0.0081 0.0346 0.1068
Echinococcus multilocularis serine:threonine protein kinase N2 0.0167 0.1175 0.1418
Echinococcus multilocularis tensin 0.006 0.0146 0.0176
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0086 0.0399 0.0481
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0673 0.0812
Loa Loa (eye worm) SRC-1 0.0265 0.2108 0.2258
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Echinococcus granulosus protein kinase c iota type 0.031 0.2537 0.2522
Schistosoma mansoni protein kinase C mu 0.0241 0.1873 0.2309
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus multilocularis transient receptor potential gamma protein 0.0428 0.3668 0.4426
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.044 0.1254
Loa Loa (eye worm) hypothetical protein 0.0207 0.1554 0.1657
Echinococcus granulosus SH2 domain containing adapter protein F 0.006 0.0146 0.0126
Entamoeba histolytica protein kinase, putative 0.0155 0.1052 0.3012
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0295
Brugia malayi phosphoinositide-dependent protein kinase I 0.0086 0.0393 0.0393
Brugia malayi Tensin 0.006 0.0146 0.0125
Brugia malayi diacylglycerol kinase 0.0053 0.0083 0.0057
Echinococcus multilocularis casein kinase I delta 0.0115 0.0673 0.0812
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0094 0.0475 0.0533
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0163 0.1136 0.5998
Toxoplasma gondii diacylglycerol kinase, putative 0.0053 0.0083 0.0221
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0216 0.02
Echinococcus granulosus defective proboscis extension response 0.006 0.0152 0.0132
Giardia lamblia Kinase, CMGC GSK 0.0137 0.0879 0.2795
Trichomonas vaginalis AGC family protein kinase 0.019 0.1386 0.4638
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0107 0.0593 0.0574
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.006 0.0146 0.0271
Echinococcus multilocularis 0.006 0.0146 0.0176
Echinococcus multilocularis SH2 domain containing adapter protein F 0.006 0.0146 0.0176
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0167 0.1175 0.1157
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0593 0.1916
Schistosoma mansoni hypothetical protein 0.0874 0.7925 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0725 0.0759
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0725 0.085
Echinococcus multilocularis activin receptor type 0.0078 0.0319 0.0385
Echinococcus multilocularis Immunoglobulin 0.006 0.0152 0.0184
Plasmodium falciparum casein kinase 2, alpha subunit 0.0106 0.0585 0.4799
Entamoeba histolytica protein kinase, putative 0.013 0.0813 0.2325
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0094 0.0475 0.1797
Schistosoma mansoni hypothetical protein 0.0205 0.153 0.1873
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0985 0.1181
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0222 0.1697 0.1813
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0319 0.1094
Schistosoma mansoni hypothetical protein 0.0205 0.153 0.1873
Plasmodium vivax casein kinase 1, putative 0.0115 0.0673 0.5796
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0866
Echinococcus multilocularis Protein lozenge 0.006 0.015 0.0181
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0091 0.044 0.0443
Echinococcus granulosus Diacylglycerol kinase theta 0.0053 0.0083 0.0063
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0093 0.0465 0.1328
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0078 0.0319 0.0385
Toxoplasma gondii AGC kinase 0.012 0.0718 0.3105
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0866
Loa Loa (eye worm) hypothetical protein 0.0107 0.0593 0.0616
Giardia lamblia Kinase, NEK 0.0145 0.0956 0.3063
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0265 0.2108 0.2092
Brugia malayi Protein-tyrosine phosphatase containing protein 0.006 0.0146 0.0125
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.164 0.47
Plasmodium vivax tyrosine kinase-like protein, putative 0.0085 0.0389 0.3213
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0169 0.1193 0.1266
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.006 0.0146 0.0271
Brugia malayi Protein kinase domain containing protein 0.0087 0.041 0.0411
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0089 0.0426 0.1215
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Plasmodium falciparum calcium-dependent protein kinase 2 0.0107 0.0593 0.487
Echinococcus multilocularis raf serine:threonine protein kinase 0.0323 0.2662 0.3212
Echinococcus multilocularis cpg binding protein 0.0099 0.0525 0.0633
Trypanosoma brucei cdc2-related kinase 3 0.0126 0.0778 0.3163
Giardia lamblia Aurora kinase 0.0155 0.1052 0.3398
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0144 0.0955 0.8353
Entamoeba histolytica protein kinase , putative 0.0155 0.1052 0.3012
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0593 0.0682
Trichomonas vaginalis AGC family protein kinase 0.0167 0.1175 0.3915
Loa Loa (eye worm) hypothetical protein 0.0155 0.1052 0.1114
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Brugia malayi Protein kinase domain containing protein 0.0167 0.1175 0.1241
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0231 0.1778 0.2146
Brugia malayi probable protein kinase 0.0283 0.2281 0.2441
Loa Loa (eye worm) TK/ROR protein kinase 0.0061 0.0162 0.0149
Echinococcus granulosus insulin growth factor 1 receptor beta 0.049 0.4254 0.4243
Echinococcus granulosus Immunoglobulin 0.006 0.0152 0.0132
Trypanosoma cruzi cyclin, putative 0.0081 0.0346 0.1523
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Echinococcus granulosus epidermal growth factor receptor 0.0429 0.3673 0.366
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0778 0.2551
Trypanosoma cruzi cyclin, putative 0.0081 0.0346 0.1523
Trypanosoma brucei protein kinase, putative 0.0078 0.0319 0.1094
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Schistosoma mansoni tyrosine kinase 0.0078 0.0323 0.0339
Schistosoma mansoni titin 0.0062 0.0167 0.0142
Loa Loa (eye worm) AGC/AKT protein kinase 0.0284 0.2293 0.2458
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0091 0.044 0.0531
Brugia malayi Protein kinase domain containing protein 0.1013 0.9251 1
Schistosoma mansoni tensin 0.006 0.0146 0.0115
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0241 0.1873 0.2004
Schistosoma mansoni protein kinase 0.0091 0.044 0.0488
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0124 0.076 0.079
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1222 0.5
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0055 0.0096 0.0116
Loa Loa (eye worm) hypothetical protein 0.012 0.0718 0.0752
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0673 0.0703
Onchocerca volvulus 0.0094 0.0473 0.1065
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0163 0.1136 0.1205
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0237 0.1843 0.2224
Brugia malayi RhoGAP domain containing protein 0.0053 0.0083 0.0057
Echinococcus granulosus tyrosine protein kinase Blk 0.0231 0.1778 0.1762
Trypanosoma brucei rac serine-threonine kinase, putative 0.0284 0.2293 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0623 0.0649
Brugia malayi tRNA modification GTPase TrmE family protein 0.006 0.0146 0.0125
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0053 0.0083 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Loa Loa (eye worm) AGC/PKA protein kinase 0.012 0.0718 0.0752
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0146 0.0126
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0673 0.0812
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0729 0.2385
Echinococcus multilocularis c src tyrosine kinase 0.0139 0.09 0.1087
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0061 0.0161 0.0434
Onchocerca volvulus 0.006 0.0146 0.0271
Loa Loa (eye worm) hypothetical protein 0.048 0.4159 0.4482
Loa Loa (eye worm) hypothetical protein 0.009 0.0435 0.0445
Echinococcus multilocularis tyrosine kinase 0.0104 0.0571 0.0689
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0237 0.1843 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.009 0.0435 0.0482
Echinococcus granulosus dual specificity 0.0091 0.044 0.042
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0126 0.0778 0.3375
Giardia lamblia Kinase, CMGC CLK 0.0163 0.1136 0.3691
Echinococcus multilocularis Immunoglobulin 0.006 0.0152 0.0184
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Brugia malayi protein kinase C II. 0.0222 0.1697 0.1807
Echinococcus granulosus mitogen activated protein kinase 0.0088 0.0417 0.0397
Echinococcus granulosus casein kinase I gamma 0.0228 0.175 0.1733
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0813 0.2325
Loa Loa (eye worm) TK protein kinase 0.0168 0.1182 0.1255
Toxoplasma gondii CMGC kinase, CK2 family 0.0106 0.0585 0.2501
Schistosoma mansoni protein kinase 0.0393 0.333 0.4161
Onchocerca volvulus 0.0207 0.1554 0.3683
Toxoplasma gondii NEK kinase 0.0053 0.0077 0.0191
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.1193 0.1439
Echinococcus multilocularis tyrosine protein kinase Srms 0.0231 0.1778 0.2146
Schistosoma mansoni growth factor receptor-bound protein 0.0094 0.0475 0.0533
Schistosoma mansoni unc-13 (munc13) 0.0055 0.0096 0.0051
Trichomonas vaginalis cyclin B, putative 0.0081 0.0346 0.1068
Echinococcus granulosus ephrin type A receptor 4 A 0.0113 0.0659 0.064
Schistosoma mansoni protein kinase 0.0067 0.0217 0.0205
Echinococcus multilocularis transient receptor potential ion channel A 0.0414 0.3532 0.4262
Brugia malayi SH2 domain containing protein 0.0431 0.3694 0.3973
Echinococcus granulosus casein kinase I delta 0.0115 0.0673 0.0654
Loa Loa (eye worm) hypothetical protein 0.0387 0.3269 0.3517
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0283 0.2282 0.2754
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0237 0.1843 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0088 0.0417 0.0397
Brugia malayi latrophilin 2 splice variant baaae 0.0113 0.0653 0.0674
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0231 0.1778 0.2146
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0087 0.041 0.1887
Loa Loa (eye worm) glutaminase 0.0309 0.2526 0.2711
Echinococcus multilocularis casein kinase i 0.0115 0.0673 0.0812
Brugia malayi Protein kinase domain containing protein 0.0303 0.2468 0.2643
Brugia malayi C1-like domain containing protein 0.0241 0.1873 0.1998
Brugia malayi serine/threonine kinase 12 0.0155 0.1052 0.1108
Schistosoma mansoni tyrosine kinase 0.0478 0.4143 0.5193
Echinococcus multilocularis epidermal growth factor receptor 0.0653 0.5816 0.7018
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0985 0.1189
Echinococcus multilocularis CDC7 cell division cycle 7 0.0095 0.0479 0.0578
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0087 0.041 0.0418
Echinococcus multilocularis snurportin 1 0.0348 0.2898 0.3496
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0175 0.1244 0.1501
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0094 0.0475 0.0489
Schistosoma mansoni cpg binding protein 0.0099 0.0525 0.0596
Loa Loa (eye worm) thyroid receptor interactor 0.0116 0.0685 0.0716
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0169 0.1193 0.5036
Echinococcus granulosus tensin 0.006 0.0146 0.0126
Brugia malayi hypothetical protein 0.0237 0.1842 0.1964
Loa Loa (eye worm) hypothetical protein 0.0159 0.1097 0.1163
Echinococcus granulosus microtubule associated protein 2 0.0747 0.6718 0.6711
Loa Loa (eye worm) hypothetical protein 0.012 0.0725 0.0759
Giardia lamblia Kinase, CMGC MAPK 0.0088 0.0417 0.1184
Echinococcus granulosus short transient receptor potential channel 6 0.0283 0.2282 0.2267
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.012 0.0718 0.6054
Loa Loa (eye worm) hypothetical protein 0.0066 0.0203 0.0193
Schistosoma mansoni SH2A 0.006 0.0146 0.0115
Echinococcus granulosus Glutaredoxin protein 5 0.0111 0.0635 0.0616
Entamoeba histolytica hypothetical protein 0.0409 0.3487 1
Schistosoma mansoni tyrosine-protein kinase zap-70 0.006 0.0146 0.0115
Echinococcus granulosus serine:threonine protein kinase N2 0.014 0.0909 0.0891
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.012 0.0718 0.2894
Brugia malayi Protein kinase domain containing protein 0.0378 0.3184 0.342
Echinococcus multilocularis twitchin 0.005 0.0056 0.0067
Schistosoma mansoni serine/threonine kinase 0.0167 0.1175 0.1422
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0214 0.1621 0.1604
Trypanosoma brucei aurora B kinase 0.0155 0.1052 0.4402
Plasmodium falciparum protein kinase 5 0.0126 0.0778 0.6615
Loa Loa (eye worm) hypothetical protein 0.048 0.4159 0.4482
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0718 0.0842
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1052 0.1114
Trypanosoma cruzi cdc2-related kinase 1 0.0126 0.0778 0.3968
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.012 0.0718 0.3105
Brugia malayi Protein kinase domain containing protein 0.0065 0.0192 0.0174
Trichomonas vaginalis STE family protein kinase 0.0091 0.044 0.1392
Loa Loa (eye worm) raf kinase 0.0279 0.2237 0.2398
Entamoeba histolytica PH domain containing protein kinase, putative 0.015 0.1011 0.2895
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.044 0.139
Echinococcus granulosus hypothetical protein 0.013 0.0817 0.0798
Echinococcus granulosus tyrosine kinase 0.0231 0.1778 0.1762
Echinococcus multilocularis growth factor receptor bound protein 2 0.0094 0.0475 0.0574
Onchocerca volvulus 0.0213 0.161 0.3821
Plasmodium vivax glycogen synthase kinase 3, putative 0.0137 0.0879 0.7667
Brugia malayi Calcitonin receptor-like protein seb-1 0.0165 0.1152 0.1215
Schistosoma mansoni protein kinase 0.0078 0.0319 0.0335
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.1139 0.1377
Schistosoma mansoni tyrosine kinase 0.0274 0.2198 0.2722
Trypanosoma brucei mitotic cyclin 6 0.0081 0.0346 0.1214
Giardia lamblia Kinase, PLK 0.0237 0.1843 0.6153
Schistosoma mansoni cpg binding protein 0.0094 0.0473 0.0531
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0057 0.0117 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.2275 0.282
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0146 0.0132
Entamoeba histolytica hypothetical protein 0.013 0.0813 0.2325
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0077 0.0144
Echinococcus granulosus raf serine:threonine protein kinase 0.0323 0.2662 0.2647
Giardia lamblia Kinase, NEK 0.0145 0.0956 0.3063
Trichomonas vaginalis STE family protein kinase 0.0089 0.0426 0.1344
Brugia malayi hypothetical protein 0.006 0.0146 0.0125
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.1621 0.1989
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0094 0.0475 0.0573
Echinococcus multilocularis expressed conserved protein 0.0148 0.0985 0.1189
Loa Loa (eye worm) hypothetical protein 0.0096 0.0491 0.0506
Trypanosoma cruzi p21-activated kinase 3, putative 0.0057 0.0117 0.0229
Echinococcus multilocularis insulin receptor 0.0478 0.4143 0.4999
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0107 0.0593 0.2535
Echinococcus granulosus protein kinase shaggy 0.0137 0.0879 0.0861
Entamoeba histolytica diacylglycerol kinase, putative 0.0053 0.0083 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0284 0.029
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.2108 0.2092
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0725 0.3669
Brugia malayi Serine/threonine-protein kinase SULU 0.0237 0.1842 0.1964
Echinococcus multilocularis calcium dependent protein kinase 0.0073 0.0273 0.033
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0094 0.0475 0.0489
Echinococcus granulosus roundabout 2 0.0101 0.0536 0.0517
Trypanosoma cruzi casein kinase, putative 0.0115 0.0673 0.3377
Brugia malayi Cyclin, N-terminal domain containing protein 0.0081 0.0346 0.0341
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0154 0.1044 0.126
Schistosoma mansoni vam6/vps39 related 0.012 0.0725 0.085
Entamoeba histolytica SH2 domain containing protein 0.006 0.0146 0.0411
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0206 0.1539 0.1642
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.006 0.0146 0.0176
Entamoeba histolytica cyclin, putative 0.0081 0.0346 0.0984
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Echinococcus multilocularis roundabout 2 0.0101 0.0536 0.0647
Leishmania major cyclin 0.0081 0.0346 0.1523
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0348 0.2898 0.3114
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.1136 0.1373
Echinococcus multilocularis death associated protein kinase 1 0.0912 0.8288 1
Plasmodium falciparum serine/threonine protein kinase KIN 0.0094 0.0475 0.3759
Echinococcus granulosus CDC7 cell division cycle 7 0.0095 0.0479 0.0459
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Onchocerca volvulus 0.0104 0.0571 0.1302
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0094 0.0475 0.2254
Plasmodium falciparum calcium-dependent protein kinase 5 0.0107 0.0593 0.487
Echinococcus granulosus aurora kinase A 0.0155 0.1052 0.1034
Schistosoma mansoni transient receptor potential channel 0.0283 0.2282 0.2829
Trypanosoma cruzi casein kinase, putative 0.0115 0.0673 0.3377
Brugia malayi glutaminase DH11.1 0.0309 0.2526 0.2706
Loa Loa (eye worm) TK/FER protein kinase 0.0431 0.3694 0.3978
Echinococcus granulosus serine threonine protein kinase nrc 0.0144 0.0955 0.0936
Loa Loa (eye worm) TK/EPH protein kinase 0.0132 0.0839 0.0883
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0176 0.126 0.134
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.2947 1
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0145 0.0956 0.4186
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.2108 0.2092
Echinococcus multilocularis cyclin dependent kinase 1 0.0126 0.0778 0.0938
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.0739 0.2419
Echinococcus multilocularis nervana 2 0.0111 0.0635 0.0767
Echinococcus multilocularis short transient receptor potential channel 6 0.0283 0.2282 0.2754
Echinococcus granulosus expressed protein 0.0087 0.041 0.0391
Plasmodium falciparum casein kinase 1 0.0115 0.0673 0.563
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0956 0.3163
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0943 0.1127
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0077 0.0144
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0126 0.0778 0.0816
Onchocerca volvulus Serine\/threonine kinase homolog 0.0175 0.1244 0.2932
Entamoeba histolytica PH domain containing protein kinase, putative 0.0126 0.0775 0.2216
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1467 0.1793
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0673 0.2192
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Plasmodium falciparum NIMA related kinase 1 0.0145 0.0956 0.83
Entamoeba histolytica protein kinase 2, putative 0.0144 0.0955 0.2732
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0154 0.1044 0.1026
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0985 0.1189
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Entamoeba histolytica protein kinase domain containing protein 0.0155 0.1052 0.3012
Entamoeba histolytica protein kinase domain containing protein 0.0106 0.0585 0.1672
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.1193 0.6318
Schistosoma mansoni tensin-related 0.006 0.0146 0.0115
Leishmania major casein kinase II, putative 0.0106 0.0585 0.2879
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0167 0.1175 0.1418
Brugia malayi cell division control protein 2 homolog 0.0126 0.0778 0.081
Echinococcus granulosus serine:threonine protein kinase 0.0121 0.0729 0.071
Trypanosoma brucei cdc2-related kinase 1 0.0126 0.0778 0.3163
Echinococcus granulosus Vam6:Vps39 protein 0.012 0.0725 0.0706
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.2108 0.2543
Echinococcus multilocularis cyclin dependent kinase 5 0.0126 0.0778 0.0938
Schistosoma mansoni hypothetical protein 0.0052 0.0074 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0393 0.1231
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0102 0.0085
Entamoeba histolytica protein kinase, putative 0.013 0.0813 0.2325
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0644 0.5731 0.6185
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0237 0.1843 0.1827
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0275 0.2198 0.2356
Echinococcus granulosus casein kinase I alpha 0.0115 0.0673 0.0654
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.1193 0.1439
Toxoplasma gondii histone kinase SNF1, putative 0.0094 0.0475 0.2
Echinococcus multilocularis dual specificity 0.0091 0.044 0.053
Entamoeba histolytica casein kinase, putative 0.0106 0.0585 0.1672
Loa Loa (eye worm) hypothetical protein 0.0052 0.0074 0.0053
Brugia malayi Protein kinase c protein 2 0.0131 0.0824 0.086
Loa Loa (eye worm) AGC/PKG protein kinase 0.0148 0.0985 0.1041
Trichomonas vaginalis STE family protein kinase 0.0091 0.044 0.1392
Echinococcus granulosus N chimaerin 0.0113 0.0655 0.0636
Echinococcus granulosus c src tyrosine kinase 0.0139 0.09 0.0882
Brugia malayi intracellular kinase 0.0137 0.0879 0.092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0346 0.0348
Loa Loa (eye worm) AUR protein kinase 0.0155 0.1052 0.1114
Schistosoma mansoni lozenge 0.006 0.015 0.0119
Schistosoma mansoni protein kinase 0.0283 0.2281 0.2828
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Loa Loa (eye worm) hypothetical protein 0.0092 0.0458 0.047
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0055 0.0104 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0856 0.2818
Onchocerca volvulus 0.006 0.0146 0.0271
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.012 0.0718 0.2894
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0866
Echinococcus multilocularis dual specificity 0.0091 0.044 0.053
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0094 0.0475 0.0488
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0417 0.1311
Giardia lamblia Kinase, CAMK CAMKL 0.0094 0.0475 0.1387
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0074 0.0053
Echinococcus granulosus nervana 2 0.0111 0.0635 0.0616
Echinococcus multilocularis basement membrane specific heparan sulfate 0.006 0.0152 0.0184
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0104 0.0571 0.1631
Brugia malayi casein kinase 1, delta 0.0115 0.0673 0.0696
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0319 0.1372
Echinococcus multilocularis mitogen activated protein kinase 0.0088 0.0417 0.0503
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Trypanosoma cruzi rac serine-threonine kinase, putative 0.015 0.1011 0.5292
Echinococcus multilocularis serine:threonine protein kinase 38 0.0167 0.1175 0.1418
Loa Loa (eye worm) TK protein kinase 0.0231 0.1778 0.1901
Entamoeba histolytica diacylglycerol kinase, putative 0.0053 0.0083 0.0231
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0198 0.1467 0.1558
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.175 0.2152
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0159 0.1097 0.1324
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.1139 0.1202
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0144 0.0955 0.8288
Brugia malayi Protein kinase domain containing protein 0.0228 0.175 0.1864
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0265 0.2105 0.254
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0155 0.1052 0.3012
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0088 0.0417 0.1924
Trichomonas vaginalis cyclins, putative 0.0055 0.0102 0.0231
Brugia malayi Stress-activated protein kinase jnk-1 0.0283 0.2275 0.2434
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.013 0.0813 0.4168
Entamoeba histolytica protein kinase, putative 0.0087 0.041 0.1169
Echinococcus granulosus NCK adaptor protein 0.0094 0.0475 0.0456
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0283 0.2275 0.2745
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0074 0.0053
Echinococcus granulosus tyrosine protein kinase Lyn 0.0298 0.2427 0.2412
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0107 0.0593 0.2535
Brugia malayi hypothetical protein 0.0072 0.0264 0.0253
Entamoeba histolytica PH domain containing protein kinase, putative 0.015 0.1011 0.2895
Echinococcus multilocularis serine:threonine protein kinase N2 0.0307 0.251 0.3028
Echinococcus multilocularis suppressor of cytokine signaling 6 0.006 0.0146 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Echinococcus granulosus nervana 2 0.0111 0.0635 0.0616
Onchocerca volvulus 0.0095 0.0479 0.1078
Brugia malayi Egg laying defective protein 4 0.0148 0.0985 0.1035
Echinococcus granulosus myotubularin protein 13 0.0059 0.014 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Brugia malayi P38 map kinase family protein 2 0.0169 0.1193 0.126
Entamoeba histolytica p21-activated kinase 0.0096 0.0497 0.1417
Schistosoma mansoni suppressor of cytokine signaling 0.006 0.0146 0.0115
Mycobacterium ulcerans glutaminase 0.0309 0.2526 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0237 0.1843 0.4385
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0359 0.3002 0.3227
Echinococcus multilocularis aurora kinase A 0.0155 0.1052 0.127
Echinococcus multilocularis tyrosine protein kinase shark 0.0334 0.2769 0.3341
Brugia malayi Immunoglobulin I-set domain containing protein 0.0453 0.3902 0.4198
Entamoeba histolytica cell division protein kinase 2, putative 0.0126 0.0778 0.2224
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0475 0.0533
Brugia malayi RhoGEF domain containing protein 0.0053 0.0083 0.0057
Entamoeba histolytica protein kinase, putative 0.0167 0.1175 0.3365
Echinococcus granulosus tyrosine protein kinase HCK 0.0171 0.1207 0.1189
Schistosoma mansoni diacylglycerol kinase theta 0.0053 0.0083 0.0035
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0089 0.0426 0.1978
Leishmania major protein kinase, putative 0.0155 0.1052 0.5523
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Echinococcus granulosus growth factor receptor bound protein 2 0.0096 0.0496 0.0477
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Schistosoma mansoni tyrosine kinase 0.0384 0.3248 0.4056
Echinococcus multilocularis cyclin dependent kinase 0.0126 0.0778 0.0938
Echinococcus granulosus protein kinase c eta type 0.0053 0.0083 0.0063
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0378 0.3184 0.7635
Schistosoma mansoni shc transforming protein 0.006 0.0146 0.0115
Onchocerca volvulus 0.0104 0.0571 0.1302
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.1136 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0475 0.0533
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0094 0.0475 0.3997
Echinococcus granulosus activin receptor type 0.0078 0.0319 0.0299
Brugia malayi SRC-1 0.0265 0.2108 0.2252
Brugia malayi casein kinase I 0.0115 0.0673 0.0696
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Onchocerca volvulus 0.0104 0.0571 0.1302
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0479 0.1524
Brugia malayi serine/threonine protein kinase 6 0.0155 0.1052 0.1108
Echinococcus multilocularis GPCR, family 2 0.0052 0.0074 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0284 0.2293 0.7752
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0163 0.1136 0.5998
Giardia lamblia Kinase, NEK 0.0145 0.0956 0.3063
Onchocerca volvulus 0.0069 0.0234 0.0484
Toxoplasma gondii NEK kinase 0.0053 0.0077 0.0191
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0077 0.0315 0.0315
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Brugia malayi Temporarily assigned gene name protein 59 0.0139 0.0903 0.0945
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0091 0.044 0.045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0102 0.0059
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0725 0.2925
Trichomonas vaginalis cyclin A, putative 0.0081 0.0346 0.1068
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0091 0.044 0.1637
Brugia malayi serine/threonine-protein kinase 6 0.0155 0.1052 0.1108
Schistosoma mansoni diacylglycerol kinase theta 0.0053 0.0083 0.0035
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0198 0.1467 0.1564
Schistosoma mansoni signal transduction protein lnk-related 0.006 0.0146 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.2052 0.2537
Loa Loa (eye worm) hypothetical protein 0.0428 0.3668 0.395
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0378 0.3184 0.3424
Entamoeba histolytica hypothetical protein 0.0053 0.0083 0.0231
Entamoeba histolytica serine/threonine protein kinase, putative 0.0237 0.1843 0.5282
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0241 0.1873 0.1998
Echinococcus granulosus NDR protein kinase 0.0167 0.1175 0.1157
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0106 0.0585 0.4998
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus multilocularis mitogen activated protein kinase 3 0.0088 0.0417 0.0503
Brugia malayi Protein kinase domain containing protein 0.0095 0.0479 0.0485
Schistosoma mansoni hypothetical protein 0.0053 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0203 0.1512 0.1612
Onchocerca volvulus 0.048 0.4159 1
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.2105 0.2604
Giardia lamblia Kinase, CAMK CAMKL 0.0094 0.0475 0.1387
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0417 0.0458
Entamoeba histolytica protein kinase, putative 0.0074 0.0284 0.0807
Echinococcus multilocularis rac serine:threonine kinase 0.015 0.1011 0.122
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0082 0.0354 0.1569
Schistosoma mansoni serine/threonine kinase 0.0232 0.1788 0.2201
Onchocerca volvulus 0.006 0.0146 0.0271
Trypanosoma cruzi casein kinase, putative 0.0115 0.0673 0.3377
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0089 0.0426 0.1215
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0086 0.0393 0.0475
Echinococcus multilocularis neuroglian 0.0077 0.0314 0.0379
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0137 0.0879 0.0927
Schistosoma mansoni transient receptor potential channel 0.0428 0.3668 0.4591
Echinococcus granulosus serine:threonine protein kinase 0.0121 0.0729 0.071
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.2947 0.8451
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.2108 0.2543
Entamoeba histolytica protein kinase, putative 0.0074 0.0284 0.0807
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0087 0.041 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus granulosus neuroglian 0.0077 0.0314 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.1697 0.2085
Loa Loa (eye worm) hypothetical protein 0.0258 0.2043 0.2188
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0088 0.0417 0.1924
Schistosoma mansoni hypothetical protein 0.011 0.0623 0.0721
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0086 0.0393 0.04
Echinococcus multilocularis cyclin B 0.0081 0.0346 0.0417
Echinococcus multilocularis unc 13 (munc13) 0.0055 0.0096 0.0116
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0088 0.0417 0.1924
Loa Loa (eye worm) hypothetical protein 0.0061 0.0156 0.0142
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0144 0.0955 0.4971
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1222 0.2992
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0393 0.1231
Echinococcus granulosus suppressor of cytokine signaling 7 0.006 0.0146 0.0126
Echinococcus multilocularis nervana 2 0.0111 0.0635 0.0767
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Echinococcus granulosus hypothetical protein 0.006 0.0146 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.1136 0.3782
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.2108 0.2543
Brugia malayi Protein kinase domain containing protein 0.0215 0.1627 0.1731
Schistosoma mansoni tyrosine kinase 0.0265 0.2108 0.2607
Onchocerca volvulus 0.0081 0.0346 0.0756
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0088 0.0417 0.1924
Trichomonas vaginalis cyclins, putative 0.0081 0.0346 0.1068
Echinococcus granulosus signal transduction protein lnk realted 0.006 0.0146 0.0126
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0091 0.044 0.0421
Echinococcus granulosus casein kinase ii subunit alpha 0.0106 0.0585 0.0566
Loa Loa (eye worm) hypothetical protein 0.0089 0.0424 0.0433
Brugia malayi protein unc-22 0.0062 0.0167 0.0148
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0087 0.041 0.1887
Echinococcus multilocularis serine:threonine protein kinase 0.0121 0.0729 0.088
Echinococcus multilocularis serine:threonine protein kinase 3 0.0275 0.2198 0.2653
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0725 0.085
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0237 0.1842 0.1825
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.053 0.4644 0.5603
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0137 0.0879 0.0861
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0077 0.0144
Brugia malayi Protein kinase domain containing protein 0.0232 0.1788 0.1906
Onchocerca volvulus 0.0055 0.0096 0.0151
Brugia malayi map kinase activated protein kinase protein 2 0.0423 0.3612 0.3884
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0126 0.0778 0.3968
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.013 0.0816 0.4187
Echinococcus multilocularis tyrosine protein kinase 0.0303 0.2468 0.2978
Entamoeba histolytica protein kinase, putative 0.0073 0.0273 0.0777
Echinococcus granulosus cyclin B 0.0081 0.0346 0.0326
Onchocerca volvulus 0.006 0.0146 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.164 0.2014
Echinococcus multilocularis casein kinase ii subunit alpha 0.0106 0.0585 0.0706
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0146 0.0176
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0378 0.3184 0.317
Trichomonas vaginalis AGC family protein kinase 0.012 0.0718 0.2346
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0126 0.0778 0.3968
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0282 0.2273 0.2743
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0086 0.0393 0.04
Echinococcus granulosus geminin 0.0205 0.153 0.1513
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.012 0.0725 0.0875
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0155 0.1052 0.1034
Echinococcus granulosus tyrosine protein kinase Src42A 0.0265 0.2108 0.2092
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.2041 0.2523
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0089 0.0426 0.1978
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0086 0.0399 0.0379
Loa Loa (eye worm) hypothetical protein 0.0154 0.1045 0.1106
Trichomonas vaginalis cyclins, putative 0.0081 0.0346 0.1068
Onchocerca volvulus 0.0154 0.1045 0.245
Onchocerca volvulus 0.0082 0.0354 0.0775
Echinococcus granulosus rho-associated protein kinase 1 0.0348 0.2902 0.2887
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0091 0.044 0.0531
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0169 0.1193 0.6318
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0778 0.0917
Trypanosoma cruzi cdc2-related kinase 3 0.0126 0.0778 0.3968
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0074 0.0277 0.0274
Loa Loa (eye worm) hypothetical protein 0.012 0.0725 0.0759
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0378 0.3184 0.3424
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0107 0.0593 0.0616
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0879 0.2515
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0102 0.0059
Echinococcus multilocularis tyrosine protein kinase Abl 0.0139 0.09 0.1087
Loa Loa (eye worm) TK protein kinase 0.0303 0.2468 0.2648
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0673 0.2192
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.006 0.0146 0.0126
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0107 0.0593 0.0715
Leishmania major protein kinase A catalytic subunit isoform 1 0.012 0.0718 0.3631
Loa Loa (eye worm) SH2 domain-containing protein 0.006 0.0146 0.0132
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0718 0.0699
Echinococcus multilocularis 0.0187 0.1362 0.1644
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0393 0.333 0.3316
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Schistosoma mansoni ephrin receptor 0.0056 0.0111 0.0071
Brugia malayi Protein kinase domain containing protein 0.0206 0.1539 0.1636
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0423 0.3612 0.4359
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0137 0.0879 0.4543
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0258 0.2041 0.2186
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0102 0.0124
Loa Loa (eye worm) hypothetical protein 0.0053 0.0083 0.0064
Echinococcus multilocularis protein kinase c eta type 0.0053 0.0083 0.0101
Entamoeba histolytica protein kinase, putative 0.0093 0.0465 0.1328
Schistosoma mansoni hypothetical protein 0.0052 0.0074 0.0023
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Trichomonas vaginalis STE family protein kinase 0.0091 0.044 0.1392
Schistosoma mansoni transient receptor potential channel 0.0283 0.2282 0.2829
Schistosoma mansoni unc-13 (munc13) 0.0057 0.0117 0.0077
Schistosoma mansoni tyrosine kinase 0.0429 0.3673 0.4597
Loa Loa (eye worm) runx1 0.006 0.015 0.0136
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0423 0.3612 0.36
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0278 0.2236 0.2397
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2947 1
Schistosoma mansoni protein kinase C mu 0.0053 0.0083 0.0035
Entamoeba histolytica protein kinase, putative 0.0073 0.0273 0.0777
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0378 0.3184 0.3842
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0258 0.2041 0.2025
Brugia malayi Protein kinase domain containing protein 0.0214 0.1621 0.1725
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.041 0.045
Loa Loa (eye worm) TK/INSR protein kinase 0.0478 0.4143 0.4464
Schistosoma mansoni hypothetical protein 0.0052 0.0074 0.0023
Echinococcus granulosus calcium activated potassium channel 0.0157 0.1079 0.1061
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0137 0.0879 0.1046
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1052 0.3493
Echinococcus multilocularis suppressor of cytokine signaling 7 0.006 0.0146 0.0176
Echinococcus multilocularis microtubule associated protein 2 0.0747 0.6718 0.8106
Brugia malayi Ras association domain family 1 isoform A 0.0053 0.0083 0.0057
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0088 0.0417 0.1534
Loa Loa (eye worm) hypothetical protein 0.0154 0.1045 0.1106
Loa Loa (eye worm) hypothetical protein 0.0497 0.4324 0.466
Brugia malayi Protein kinase domain containing protein 0.0644 0.5731 0.6182
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0585 0.189
Loa Loa (eye worm) hypothetical protein 0.025 0.1962 0.21
Schistosoma mansoni glutaminase 0.0309 0.2526 0.3138
Brugia malayi SH2 domain containing protein 0.006 0.0146 0.0125
Trichomonas vaginalis AGC family protein kinase 0.019 0.1386 0.4638
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0161 0.0434
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0231 0.1778 0.1761
Brugia malayi Protein kinase domain containing protein 0.0299 0.2435 0.2607
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0102 0.0077
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0085 0.0389 0.2943
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0475 0.0482
Brugia malayi Protein kinase domain containing protein 0.019 0.1386 0.1469
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0943 0.1127
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0053 0.0077 0.0381
Schistosoma mansoni hypothetical protein 0.0052 0.0074 0.0023
Schistosoma mansoni serine/threonine-protein kinase 0.015 0.1011 0.1214
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0137 0.0879 0.1061
Echinococcus granulosus short transient receptor potential channel 6 0.0283 0.2282 0.2267
Brugia malayi SH2 domain containing protein 0.0104 0.0571 0.0586
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0985 0.0967
Schistosoma mansoni protein kinase 0.0465 0.4021 0.5039
Trypanosoma cruzi cdc2-related kinase 1 0.0126 0.0778 0.3968
Echinococcus multilocularis casein kinase I gamma 0.0228 0.175 0.2111
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0231 0.1778 0.1761
Trichomonas vaginalis AGC family protein kinase 0.0155 0.1052 0.3493
Brugia malayi Protein kinase domain containing protein 0.0104 0.0571 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.044 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.1843 0.6209
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0081 0.0346 0.1523
Echinococcus granulosus TRP transient receptor potential channel 0.0159 0.1097 0.1079
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0077 0.0027
Plasmodium falciparum cGMP-dependent protein kinase 0.0148 0.0985 0.8574
Trypanosoma cruzi cyclin 6, putative 0.0081 0.0346 0.1523
Brugia malayi hypothetical protein 0.048 0.4159 0.4478
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0113 0.0655 0.079
Brugia malayi hypothetical protein 0.0104 0.0571 0.0586
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0475 0.0482
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.006 0.0152 0.0123
Plasmodium vivax serine/threonine protein kinase, putative 0.0087 0.041 0.3408
Echinococcus multilocularis dual specificity 0.0091 0.044 0.053
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0479 0.1524
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0057 0.0117 0.0283
Echinococcus granulosus c-Jun N-terminal kinases 0.0283 0.2275 0.2259
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.1788 0.602
Leishmania major protein kinase, putative 0.0089 0.0426 0.1978
Echinococcus granulosus SH2 domain containing protein 7 0.006 0.0146 0.0126
Loa Loa (eye worm) hypothetical protein 0.0149 0.1003 0.1061
Brugia malayi Temporarily assigned gene name protein 59 0.012 0.0725 0.0752
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0145 0.0956 0.8365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0074 0.0089
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0107 0.0593 0.0609
Leishmania major protein kinase A catalytic subunit isoform 2 0.012 0.0718 0.3631
Echinococcus multilocularis epidermal growth factor receptor 0.0429 0.3673 0.4432
Schistosoma mansoni hypothetical protein 0.012 0.0725 0.085
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0479 0.1524
Loa Loa (eye worm) hypothetical protein 0.0059 0.014 0.0125
Echinococcus granulosus tyrosine protein kinase ABL1 0.0104 0.0571 0.0552
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0479 0.0537
Echinococcus granulosus histone acetyltransferase KAT2B 0.0159 0.1095 0.1077
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0718 0.0842
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0151 0.102 0.1231
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.2947 0.5
Schistosoma mansoni tyrosine kinase 0.0073 0.0272 0.0274
Entamoeba histolytica protein kinase, putative 0.0108 0.0606 0.173
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0393 0.333 0.3583
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0475 0.1511
Loa Loa (eye worm) hypothetical protein 0.0104 0.0571 0.0593
Brugia malayi Protein kinase domain containing protein 0.0478 0.4143 0.4459
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0417 0.1311
Entamoeba histolytica protein kinase, putative 0.0137 0.0879 0.2515
Brugia malayi protein-tyrosine kinase 0.0231 0.1778 0.1895
Brugia malayi Doublecortin family protein 0.016 0.1107 0.1167
Schistosoma mansoni hypothetical protein 0.0348 0.2898 0.3611
Trypanosoma brucei protein kinase, putative 0.0088 0.0417 0.1534
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1222 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0879 0.2515
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0265 0.2108 0.2543
Echinococcus multilocularis rho associated protein kinase 0.0348 0.2902 0.3501
Leishmania major protein kinase, putative 0.0163 0.1136 0.5998
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0265 0.2108 0.2543
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0393 0.333 0.4018
Trypanosoma cruzi aurora B kinase, putative 0.0155 0.1052 0.5523
Toxoplasma gondii aurora kinase 0.0155 0.1052 0.4623
Loa Loa (eye worm) TK/ALK protein kinase 0.0299 0.2434 0.2612
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0453 0.3902 0.4203
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0183 0.1319 0.1403
Loa Loa (eye worm) CDC7 protein kinase 0.0095 0.0479 0.0492
Echinococcus multilocularis serine:threonine protein kinase N2 0.014 0.0909 0.1097
Trypanosoma cruzi CYC2-like cyclin, putative 0.0081 0.0346 0.1523
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0265 0.2108 0.2543
Leishmania major protein kinase, putative 0.0078 0.0319 0.1372
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0879 0.2899
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.009 0.0435 0.0438
Loa Loa (eye worm) RasGEF domain-containing protein 0.0056 0.0108 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0417 0.1311
Onchocerca volvulus 0.0062 0.0167 0.0323
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0088 0.0417 0.1735
Entamoeba histolytica protein kinase, putative 0.0107 0.0593 0.1693
Echinococcus multilocularis signal transduction protein lnk realted 0.006 0.0146 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0104 0.0239
Trichomonas vaginalis cyclin B, putative 0.0081 0.0346 0.1068
Echinococcus granulosus tyrosine kinase 0.0104 0.0571 0.0552
Onchocerca volvulus 0.0315 0.2582 0.6177
Loa Loa (eye worm) TK/EGFR protein kinase 0.0653 0.5816 0.6277
Plasmodium vivax protein kinase, putative 0.0061 0.0155 0.1092
Schistosoma mansoni serine/threonine protein kinase 0.0378 0.3184 0.3975
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0107 0.0593 0.0616
Echinococcus granulosus calcium dependent protein kinase 0.0073 0.0273 0.0254
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0163 0.1136 0.5998
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0087 0.041 0.1705
Echinococcus multilocularis Rac GTPase activating protein 1 0.0053 0.0083 0.0101
Brugia malayi Raf kinase 0.027 0.2153 0.2302
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0078 0.0319 0.0299
Schistosoma mansoni protein kinase 0.0206 0.1539 0.1885
Echinococcus granulosus dual specificity protein kinase clk2 0.0163 0.1136 0.1118
Echinococcus multilocularis dual specificity protein kinase clk2 0.0163 0.1136 0.1371
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0475 0.0533
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0216 0.0207
Echinococcus granulosus casein kinase I alpha 0.0115 0.0673 0.0654
Echinococcus multilocularis N chimaerin 0.0113 0.0655 0.079
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0165 0.1152 0.1222
Brugia malayi Transient-receptor-potential like protein 0.0159 0.1097 0.1156
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0074 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0475 0.0533
Loa Loa (eye worm) TK protein kinase 0.0371 0.3123 0.3358
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0259 0.2052 0.2036
Giardia lamblia Kinase, CMGC DYRK 0.0091 0.044 0.1264
Echinococcus multilocularis calcium activated potassium channel 0.0157 0.1079 0.1302
Loa Loa (eye worm) hypothetical protein 0.013 0.0817 0.0859
Plasmodium falciparum calcium-dependent protein kinase 1 0.0107 0.0593 0.487
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0571 0.0593
Trichomonas vaginalis STE family protein kinase 0.0091 0.044 0.1392
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0102 0.0059
Echinococcus multilocularis titin 0.0062 0.0167 0.0202
Echinococcus granulosus tensin C1 domain containing phosphatase 0.006 0.0146 0.0126
Echinococcus multilocularis Glutaredoxin protein 5 0.0111 0.0635 0.0767
Trypanosoma cruzi casein kinase, putative 0.0115 0.0673 0.3377
Leishmania major protein kinase, putative 0.0163 0.1136 0.5998
Giardia lamblia Kinase, AGC AKT 0.0124 0.076 0.2379

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 19.9054 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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