Detailed information for compound 1329062

Basic information

Technical information
  • TDR Targets ID: 1329062
  • Name: (4-butoxy-3-nitrophenyl)methylsulfanylmethani midamide hydrochloride
  • MW: 319.808 | Formula: C12H18ClN3O3S
  • H donors: 1 H acceptors: 2 LogP: 3.52 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCOc1ccc(cc1[N+](=O)[O-])CSC(=N)N.Cl
  • InChi: 1S/C12H17N3O3S.ClH/c1-2-3-6-18-11-5-4-9(8-19-12(13)14)7-10(11)15(16)17;/h4-5,7H,2-3,6,8H2,1H3,(H3,13,14);1H
  • InChiKey: ZGHVWJQMZGWRAI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (4-butoxy-3-nitro-phenyl)methylsulfanylformamidine hydrochloride
  • [(4-butoxy-3-nitrophenyl)methylthio]formamidine hydrochloride
  • [(4-butoxy-3-nitro-benzyl)thio]formamidine hydrochloride
  • (4-butoxy-3-nitro-phenyl)methylsulfanylmethanimidamide hydrochloride
  • 2-(4-Butoxy-3-nitro-benzyl)-isothiourea
  • MLS000552577
  • SMR000146092

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus solute carrier family 22 0.006 0.0268 0.073
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0897 0.3891
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0021 0.0052 0.0078
Trypanosoma brucei histidyl-tRNA synthetase 0.0014 0.0014 0.0073
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0128 0.0646 0.7892
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0227 0.0527
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Brugia malayi Muscleblind-like protein 0.0164 0.0841 0.3173
Echinococcus granulosus pyruvate kinase 0.0019 0.004 0.0108
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0181 0.0786
Brugia malayi MH2 domain containing protein 0.0015 0.0016 0.0028
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0157 0.0804 1
Echinococcus granulosus importin subunit beta 1 0.0028 0.009 0.0244
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Plasmodium falciparum glycine--tRNA ligase 0.0014 0.0014 0.0014
Echinococcus granulosus muscleblind protein 0.0164 0.0841 0.2294
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0014 0.0014 0.0038
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0013 0.0009 0.002
Plasmodium falciparum aspartate--tRNA ligase 0.0014 0.0014 0.0014
Mycobacterium leprae Probable lipase LipE 0.0074 0.0347 0.3919
Treponema pallidum thioredoxin reductase (trxB) 0.0157 0.0804 0.4665
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.014 0.05
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.0801 0.9956
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.006 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0268 0.116
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0113 0.0399
Trypanosoma cruzi glucose transporter, putative 0.006 0.0268 0.3429
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0083 0.0285
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0014 0.0032
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0009 0.0024
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0016 0.0044
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0009 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0181 0.0421
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0009 0.002
Giardia lamblia Lysyl-tRNA synthetase 0.0095 0.0463 0.2267
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0476 0.2571 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0147 0.0747 0.2039
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0347 0.0946
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0024 0.0068 0.0779
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.067 0.8756
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0488 0.1332
Echinococcus granulosus potassium large conductance calcium activated 0.0013 0.0009 0.0024
Loa Loa (eye worm) transcription factor SMAD2 0.0486 0.2631 1
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0024 0.0068 0.0224
Plasmodium falciparum calcium-dependent protein kinase 2 0.0131 0.0661 0.0661
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0013 0.0009 0.002
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0051 0.0119
Onchocerca volvulus 0.006 0.0268 0.2763
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Leishmania major lysyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Brugia malayi major facilitator superfamily protein 0.006 0.0268 0.0987
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1594 0.6046
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0347 0.1289
Mycobacterium ulcerans beta-lactamase 0.0074 0.0347 0.4212
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0212 0.269
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.01 0.0273
Brugia malayi RNA, U transporter 1 0.008 0.0376 0.1402
Brugia malayi Cam kinase protein 1 0.0131 0.066 0.2485
Loa Loa (eye worm) pyruvate kinase 0.0037 0.014 0.05
Onchocerca volvulus 0.006 0.0268 0.2763
Schistosoma mansoni sugar transporter 0.006 0.0268 0.073
Plasmodium vivax threonine--tRNA ligase, putative 0.0024 0.0068 0.0068
Brugia malayi beta-lactamase 0.0074 0.0347 0.1289
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0051 0.0563
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.01 0.0488 0.1829
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Plasmodium falciparum pyruvate kinase 0.0037 0.014 0.014
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0014 0.0014 0.0062
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus multilocularis synaptic vesicle 2 protein 0.006 0.0268 0.0621
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0131 0.0661 0.0996
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0014 0.0039
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0108 0.0534 0.2615
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.067 0.8756
Echinococcus multilocularis GPCR, family 2 0.0147 0.0747 0.1735
Brugia malayi MH1 domain containing protein 0.0033 0.0118 0.0416
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0191 0.0522
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Brugia malayi hypothetical protein 0.005 0.0212 0.0774
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0181 0.0786
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0024 0.0068 0.0224
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0147 0.0747 0.2817
Echinococcus multilocularis muscleblind protein 0.0164 0.0841 0.1952
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0504
Loa Loa (eye worm) hypothetical protein 0.0069 0.0315 0.117
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0268 0.0987
Plasmodium vivax histidine--tRNA ligase, putative 0.0014 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Schistosoma mansoni hypothetical protein 0.0013 0.0009 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0268 0.116
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0009 0.0024
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0191 0.0522
Giardia lamblia Threonyl-tRNA synthetase 0.0024 0.0068 0.033
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0131 0.0661 0.0996
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0157 0.0804 0.3488
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0009 0.0024
Onchocerca volvulus 0.006 0.0268 0.2763
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0013 0.0009 0.002
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Entamoeba histolytica hypothetical protein 0.0095 0.0463 0.2267
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0009 0.002
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0053 0.0226 0.0829
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0052 0.0573
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0181 0.2287
Schistosoma mansoni smad 0.0033 0.0118 0.0321
Onchocerca volvulus 0.006 0.0268 0.2763
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0009 0.002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1533
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0347 0.0946
Loa Loa (eye worm) hypothetical protein 0.0037 0.014 0.05
Mycobacterium tuberculosis Conserved protein 0.0074 0.0347 0.1173
Schistosoma mansoni hypothetical protein 0.003 0.01 0.0273
Entamoeba histolytica hypothetical protein 0.0074 0.0347 0.1698
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0049 0.0073
Brugia malayi latrophilin 2 splice variant baaae 0.0317 0.1691 0.6416
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1802
Entamoeba histolytica protein kinase, putative 0.0131 0.066 0.323
Brugia malayi beta-lactamase family protein 0.0074 0.0347 0.1289
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Giardia lamblia Hexose transporter 0.006 0.0268 0.1309
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Trypanosoma cruzi hexose transporter 0.0133 0.067 0.8756
Loa Loa (eye worm) pyruvate kinase 0.0037 0.014 0.05
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0347 0.1173
Loa Loa (eye worm) sugar transporter 0.0428 0.2306 0.8761
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0268 0.0987
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.0801 0.9954
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0024 0.0068 0.0779
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0009 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0013 0.0009 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0135 0.0313
Loa Loa (eye worm) PHD-finger family protein 0.003 0.01 0.0348
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0118 0.0321
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0083 0.0194
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0118 0.0321
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0191 0.0522
Trichomonas vaginalis sugar transporter, putative 0.0133 0.067 0.2904
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0128 0.0646 0.2429
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0115 0.1409
Loa Loa (eye worm) inositol-1 0.0045 0.0181 0.0658
Echinococcus multilocularis dna polymerase eta 0.0021 0.0051 0.0119
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Onchocerca volvulus 0.006 0.0268 0.2763
Loa Loa (eye worm) hypothetical protein 0.0021 0.0051 0.0162
Brugia malayi major facilitator superfamily protein 0.006 0.0268 0.0987
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0024 0.0068 0.0779
Giardia lamblia TCP-1 chaperonin subunit beta 0.0027 0.0083 0.0408
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0256 0.0594
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0013 0.0009 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Brugia malayi Sugar transporter family protein 0.006 0.0268 0.0987
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0051 0.014
Echinococcus multilocularis two pore calcium channel protein 1 0.0013 0.0009 0.002
Brugia malayi glycyl-tRNA synthetase 0.0024 0.0068 0.0224
Brugia malayi follicle stimulating hormone receptor 0.0233 0.1226 0.4643
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0347 0.1504
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0131 0.0661 0.0996
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0056 0.0129
Trypanosoma brucei glucose transporter 1E 0.0133 0.067 0.8756
Echinococcus granulosus geminin 0.0673 0.3665 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.015 0.0764 0.1151
Echinococcus granulosus solute carrier family 22 0.006 0.0268 0.073
Schistosoma mansoni inositol monophosphatase 0.0045 0.0181 0.0495
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.014 0.1399
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0347 0.1504
Echinococcus multilocularis importin subunit beta 1 0.0028 0.009 0.0208
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0009 0.002
Onchocerca volvulus 0.006 0.0268 0.2763
Echinococcus granulosus shaker cognate 0.0013 0.0009 0.0024
Trichomonas vaginalis glucose transporter, putative 0.0133 0.067 0.2904
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni smad1 5 8 and 0.0033 0.0118 0.0321
Trypanosoma brucei glucose transporter 2A 0.0133 0.067 0.8756
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0026 0.0071
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0024 0.0068 0.033
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0014 0.0038
Onchocerca volvulus 0.0074 0.0347 0.3608
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0009 0.002
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0128 0.0646 0.1761
Plasmodium vivax importin-beta 2, putative 0.0028 0.009 0.009
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0115 0.0267
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.01 0.0232
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0052 0.0003
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus calcium activated potassium channel 0.0022 0.0054 0.0148
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.0308
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0024 0.0068 0.0293
Leishmania major hypothetical protein, conserved 0.0021 0.0052 0.0573
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0128 0.0646 0.1761
Entamoeba histolytica hypothetical protein 0.0074 0.0347 0.1698
Echinococcus granulosus voltage gated hydrogen channel 1 0.0013 0.0009 0.0024
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0115 0.1409
Loa Loa (eye worm) hypothetical protein 0.0182 0.0946 0.3573
Brugia malayi beta-lactamase family protein 0.0074 0.0347 0.1289
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0083 0.0988
Leishmania major DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0009 0.0021
Echinococcus multilocularis voltage dependent calcium channel 0.0013 0.0009 0.002
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0045 0.0185 0.2171
Echinococcus granulosus smad 0.0033 0.0118 0.0321
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0009 0.0024
Schistosoma mansoni Smad4 0.0015 0.0016 0.0044
Schistosoma mansoni sugar transporter 0.006 0.0268 0.073
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0016 0.0028
Onchocerca volvulus 0.006 0.0268 0.2763
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0083 0.0227
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0124
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0095 0.0463 0.6025
Plasmodium vivax sugar transporter, putative 0.006 0.0268 0.0268
Echinococcus multilocularis solute carrier family 22 0.006 0.0268 0.0621
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0081 0.0384 0.132
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0095 0.0463 0.5471
Brugia malayi intermediate filament protein 0.006 0.0269 0.0992
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0009 0.0024
Echinococcus multilocularis solute carrier family 22 0.006 0.0268 0.0621
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0051 0.0222
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0014 0.0014 0.007
Schistosoma mansoni histidyl-tRNA synthetase 0.0014 0.0014 0.0039
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0013 0.0009 0.0024
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0115 0.0115
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni ran 0.0021 0.0049 0.0132
Plasmodium vivax CDK-related protein kinase 6, putative 0.1816 1 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0227 0.0527
Brugia malayi MH2 domain containing protein 0.0486 0.2631 1
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.066 0.2864
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0013 0.0009 0.002
Brugia malayi Bromodomain containing protein 0.0073 0.0339 0.1258
Schistosoma mansoni two-pore calcium channel 0.0013 0.0009 0.0024
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0183 0.0948 0.22
Brugia malayi Sugar transporter family protein 0.006 0.0268 0.0987
Schistosoma mansoni threonyl-tRNA synthetase 0.0014 0.0014 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0428 0.2306 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0488 0.1134
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0009 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0157 0.0804 0.3488
Echinococcus multilocularis lamin 0.006 0.0269 0.0624
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0045
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2306 0.6291
Giardia lamblia PHD finger protein 15 0.003 0.01 0.0489
Leishmania major importin beta-1 subunit, putative 0.0023 0.006 0.0681
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Plasmodium falciparum importin beta, putative 0.0028 0.009 0.009
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0051 0.0563
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0024 0.0068 0.0065
Echinococcus multilocularis pyruvate kinase 0.0029 0.0096 0.0224
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0381 0.2044 1
Toxoplasma gondii sugar transporter ST2 0.006 0.0268 0.0403
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0212 0.0319
Toxoplasma gondii sugar transporter ST1 0.006 0.0268 0.0403
Trypanosoma brucei unspecified product 0.0015 0.0015 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0191 0.0696
Toxoplasma gondii lysine-tRNA ligase 0.0095 0.0463 0.0699
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0009 0.002
Plasmodium falciparum calcium-dependent protein kinase 3 0.0131 0.0661 0.0661
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.0083 0.0408
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Trypanosoma cruzi hexose transporter, putative 0.0073 0.0336 0.4338
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0013 0.0009 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0347 0.4212
Echinococcus multilocularis sodium leak channel non selective protein 0.0013 0.0009 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0115 0.0406
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0347 0.1173
Trypanosoma cruzi hexose transporter, putative 0.0133 0.067 0.8756
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0181 0.2287
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Echinococcus granulosus TRP transient receptor potential channel 0.015 0.0767 0.2092
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0212 0.269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0488 0.1332
Schistosoma mansoni transient receptor potential channel 0.0267 0.1415 0.3861
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0191 0.0444
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0028
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0128 0.0646 0.1761
Echinococcus multilocularis short transient receptor potential channel 6 0.0267 0.1415 0.3286
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.014 0.0606
Trichomonas vaginalis ran, putative 0.0021 0.0049 0.021
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0013 0.0009 0.0024
Toxoplasma gondii anticodon binding domain-containing protein 0.0014 0.0014 0.0021
Schistosoma mansoni hypothetical protein 0.0022 0.0059 0.016
Schistosoma mansoni hypothetical protein 0.0673 0.3665 1
Giardia lamblia DNA repair protein RAD52 0.0381 0.2044 1
Onchocerca volvulus 0.006 0.0268 0.2763
Loa Loa (eye worm) hypothetical protein 0.0024 0.0068 0.0224
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0081 0.0384 0.132
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0269 0.0992
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2306 0.5354
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0145 0.052
Schistosoma mansoni voltage-gated cation channel 0.0013 0.0009 0.0024
Schistosoma mansoni hypothetical protein 0.0147 0.0747 0.2039
Echinococcus multilocularis pyruvate kinase 0.0019 0.004 0.0092
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0118 0.0321
Schistosoma mansoni hypothetical protein 0.0299 0.1594 0.4349
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Brugia malayi Calcitonin receptor-like protein seb-1 0.0464 0.2504 0.9517
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0015 0.0081
Loa Loa (eye worm) beta-lactamase 0.0074 0.0347 0.1289
Brugia malayi mbt repeat family protein 0.0046 0.0191 0.0696
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0049 0.0527
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0227 0.0619
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1802
Leishmania major asparaginyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0181 0.0786
Loa Loa (eye worm) hypothetical protein 0.0164 0.0841 0.3173
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0095 0.0463 0.5689
Echinococcus granulosus snurportin 1 0.0299 0.1594 0.4349
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0347 0.1173
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0095 0.0463 0.201
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Mycobacterium ulcerans hypothetical protein 0.0074 0.0347 0.4212
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Entamoeba histolytica hypothetical protein 0.0023 0.006 0.0294
Echinococcus granulosus calcium dependent protein kinase 0.0123 0.0615 0.1679
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0014 0.0014 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.009 0.1071
Echinococcus granulosus Sugar transporter ERD6 protein 0.006 0.0268 0.073
Schistosoma mansoni smad1 5 8 and 0.0033 0.0118 0.0321
Entamoeba histolytica hypothetical protein 0.0074 0.0347 0.1698
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0225
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0157 0.0804 0.2988
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.006 0.0268 0.321
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.01 0.0151
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0051 0.0472
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0212 0.0212
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0014 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0096 0.0331
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0014 0.0014 0.0032
Schistosoma mansoni glucose transport protein 0.0428 0.2306 0.6291
Giardia lamblia Fructose-bisphosphate aldolase 0.032 0.1708 0.8356
Onchocerca volvulus Putative transporter 0.006 0.0268 0.2763
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Leishmania major hypothetical protein, conserved 0.006 0.0268 0.3429
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.01 0.0488 0.1829
Brugia malayi Inositol-1 0.0045 0.0181 0.0658
Onchocerca volvulus 0.006 0.0268 0.2763
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0347 0.4479
Trichomonas vaginalis sugar transporter, putative 0.0133 0.067 0.2904
Brugia malayi Importin beta-1 subunit 0.0028 0.009 0.0308
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0024 0.0068 0.0102
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Echinococcus multilocularis lamin dm0 0.006 0.0269 0.0624
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0488 0.1134
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0014 0.0014 0.0004
Loa Loa (eye worm) 63kd antigen 0.0014 0.0014 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0051 0.0162
Schistosoma mansoni voltage-dependent calcium channel 0.0013 0.0009 0.0024
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2306 0.5354
Mycobacterium ulcerans lipase LipD 0.0074 0.0347 0.4212
Onchocerca volvulus 0.006 0.0268 0.2763
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0009 0.002
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.015 0.0764 1
Onchocerca volvulus 0.0046 0.0191 0.1949
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.006 0.0268 0.0859
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0051 0.0162
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0157 0.0804 0.3488
Echinococcus granulosus short transient receptor potential channel 6 0.0267 0.1415 0.3861
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0277 0.1022
Echinococcus multilocularis transient receptor potential gamma protein 0.0404 0.2173 0.5046
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0115 0.0314
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus dna polymerase eta 0.0021 0.0051 0.014
Toxoplasma gondii ABC1 family protein 0.0074 0.0347 0.0523
Echinococcus granulosus pyruvate kinase 0.0019 0.004 0.0108
Plasmodium vivax aspartate--tRNA ligase, putative 0.0014 0.0014 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Entamoeba histolytica hypothetical protein 0.0074 0.0347 0.1698
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0014 0.0014 0.0062
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0464 0.2504 0.9517
Trypanosoma cruzi hexose transporter, putative 0.006 0.0268 0.3429
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0118 0.0274
Brugia malayi PHD-finger family protein 0.003 0.01 0.0348
Loa Loa (eye worm) pyruvate kinase 0.0037 0.014 0.05
Echinococcus granulosus transient receptor potential gamma protein 0.0404 0.2173 0.5929
Trichomonas vaginalis importin beta-1, putative 0.0023 0.006 0.0261
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0165 0.045
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0347 0.0806
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0118 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0052 0.0573
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0049 0.0049
Trichomonas vaginalis glucose transporter, putative 0.0133 0.067 0.2904
Brugia malayi Bromodomain containing protein 0.0037 0.0141 0.0503
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0212 0.0212
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.009 0.0135
Schistosoma mansoni transient receptor potential channel 4 0.0404 0.2173 0.5929
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0181 0.0495
Plasmodium vivax lysine--tRNA ligase, putative 0.0095 0.0463 0.0463
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0024 0.0068 0.0679
Toxoplasma gondii protein kinase, putative 0.1209 0.6635 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2306 0.6291
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0083 0.0988
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0052 0.0573
Leishmania major glucose transporter/membrane transporter D2, putative 0.0133 0.067 0.8756
Onchocerca volvulus 0.0074 0.0347 0.3608
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.014 0.1399
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0103
Schistosoma mansoni glucose transport protein 0.0428 0.2306 0.6291
Leishmania major protein kinase, putative 0.0131 0.066 0.8633
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.014 0.1736
Leishmania major glucose transporter, lmgt2 0.0133 0.067 0.8756
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0026 0.0071
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.0764 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0147 0.0747 0.1735
Giardia lamblia Asparaginyl-tRNA synthetase 0.0014 0.0014 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Schistosoma mansoni voltage-gated ion channel 0.0013 0.0009 0.0024
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0225
Onchocerca volvulus 0.0182 0.0946 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0157 0.0804 0.3488
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0347 0.1504
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0145 0.0396
Echinococcus multilocularis sodium channel protein 0.0013 0.0009 0.002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0269 0.0992
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0009 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.006 0.0261
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0051 0.014
Schistosoma mansoni importin beta-1 0.0028 0.009 0.0244
Echinococcus multilocularis shaker cognate 0.0013 0.0009 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0051 0.0472
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.1708 0.8356
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Echinococcus granulosus lamin 0.006 0.0269 0.0733
Toxoplasma gondii transporter, major facilitator family protein 0.006 0.0268 0.0403
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0083 0.0083
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0157 0.0804 0.3488
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1802
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0115 0.1409
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0347 0.0347
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0051 0.0563
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0897 0.3891
Schistosoma mansoni protein kinase 0.0131 0.066 0.1802
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.1327 0.5027
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0026 0.0071
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0115 0.0173
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0009 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0013 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0089 0.0308
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0009 0.0024
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0128 0.0349
Trichomonas vaginalis sugar transport protein, putative 0.006 0.0268 0.116
Entamoeba histolytica thioredoxin reductase, putative 0.0157 0.0804 0.3934
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0118 0.0416
Trypanosoma brucei unspecified product 0.0021 0.0051 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0225
Brugia malayi lysyl-tRNA synthetase 0.0095 0.0463 0.1734
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0268 0.116
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0014 0.0014
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0013 0.0009 0.0024
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Leishmania major hypothetical protein, conserved 0.0021 0.0052 0.0573
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Plasmodium falciparum histidine--tRNA ligase, putative 0.0014 0.0014 0.0014
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Onchocerca volvulus 0.006 0.0268 0.2763
Schistosoma mansoni lamin 0.006 0.0269 0.0733
Treponema pallidum prolyl-tRNA synthetase 0.0045 0.0185 0.1013
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0014 0.0014 0.006
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0024 0.0068 0.0157
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1533
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0347 0.1173
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0026 0.0071
Echinococcus multilocularis pyruvate kinase 0.0037 0.014 0.0325
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0128 0.0646 0.28
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Plasmodium falciparum lysine--tRNA ligase 0.0095 0.0463 0.0463
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0083 0.0285
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0024 0.0068 0.0206
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0009 0.0025
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Onchocerca volvulus 0.006 0.0268 0.2763
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0009 0.0024
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0014 0.0014 0.0032
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0115 0.0267
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Loa Loa (eye worm) hypothetical protein 0.0041 0.0164 0.0592
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0347 0.0947
Brugia malayi hypothetical protein 0.006 0.0268 0.0987
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0131 0.066 0.8633
Echinococcus multilocularis conserved hypothetical protein 0.0013 0.0009 0.002
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Chlamydia trachomatis proline--tRNA ligase 0.0045 0.0185 0.2171
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0115 0.0267
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0145 0.0396
Echinococcus multilocularis lysyl tRNA synthetase 0.0095 0.0463 0.1076
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0268 0.116
Brugia malayi MH1 domain containing protein 0.0018 0.0036 0.0103
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0009 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0133 0.067 0.2904
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0118 0.0416
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0016 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0015 0.0081
Giardia lamblia Sugar-proton symporter 0.006 0.0268 0.1309
Loa Loa (eye worm) hypothetical protein 0.0464 0.2504 0.9517
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0347 0.0946
Toxoplasma gondii facilitative glucose transporter GT1 0.0428 0.2306 0.3475
Schistosoma mansoni hypothetical protein 0.0317 0.1691 0.4613
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0145 0.0396
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Trichomonas vaginalis myo-inositol transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0013 0.0009 0.0024
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0009 0.0024
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0014 0.0014
Chlamydia trachomatis histidine--tRNA ligase 0.0014 0.0014 0.0004
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.014 0.1736
Brugia malayi isocitrate dehydrogenase 0.0033 0.0115 0.0406
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0157 0.0804 1
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Echinococcus multilocularis snurportin 1 0.0299 0.1594 0.3701
Leishmania major pyruvate kinase 0.0037 0.014 0.1736
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0014 0.0014 0.002
Schistosoma mansoni bromodomain containing protein 0.0062 0.0275 0.0751
Plasmodium falciparum asparagine--tRNA ligase 0.0014 0.0014 0.0014
Schistosoma mansoni pyruvate kinase 0.0019 0.004 0.0108
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.006 0.0268 0.3429
Loa Loa (eye worm) hypothetical protein 0.0404 0.2173 0.8255
Plasmodium falciparum hexose transporter 0.0428 0.2306 0.2306
Schistosoma mansoni hypothetical protein 0.0673 0.3665 1
Onchocerca volvulus 0.006 0.0269 0.2775
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) sugar transporter 0.006 0.0268 0.0987
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0428 0.2306 0.5354
Loa Loa (eye worm) hypothetical protein 0.0104 0.0512 0.192
Schistosoma mansoni lysyl-tRNA synthetase 0.0095 0.0463 0.1265
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0049 0.0527
Echinococcus granulosus pyruvate kinase 0.0037 0.014 0.0381
Toxoplasma gondii sugar transporter ST3 0.006 0.0268 0.0403
Loa Loa (eye worm) MH2 domain-containing protein 0.0486 0.2631 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0191 0.1949
Treponema pallidum threonyl-tRNA synthetase 0.0024 0.0068 0.0317
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0183 0.0948 0.2586
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0013 0.0009 0.0024
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0056 0.0152
Schistosoma mansoni pyruvate kinase 0.0037 0.014 0.0381
Chlamydia trachomatis pyruvate kinase 0.0037 0.014 0.1593
Schistosoma mansoni ran 0.0021 0.0049 0.0132
Echinococcus granulosus hypothetical protein 0.0013 0.0009 0.0024
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0051 0.0563
Trichomonas vaginalis esterase, putative 0.0074 0.0347 0.1504
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0164 0.0841 0.3173
Brugia malayi MH2 domain containing protein 0.0033 0.0118 0.0416
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0026 0.0071
Schistosoma mansoni vesicular amine transporter 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.006 0.0268 0.0268
Echinococcus multilocularis pyruvate kinase 0.0019 0.004 0.0092
Echinococcus multilocularis transient receptor potential ion channel A 0.039 0.2099 0.4872
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0049 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Echinococcus granulosus sodium channel protein 0.0013 0.0009 0.0024
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0009 0.0024
Echinococcus multilocularis TRP (transient receptor potential) channel 0.015 0.0767 0.178
Plasmodium falciparum proline--tRNA ligase 0.015 0.0764 0.0764
Echinococcus granulosus Smad4 0.0033 0.0118 0.0321
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.014 0.1167
Giardia lamblia Thioredoxin reductase 0.0157 0.0804 0.3934
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0147 0.0747 0.2039
Giardia lamblia Pyruvate kinase 0.0019 0.004 0.0194
Echinococcus granulosus transient receptor potential ion channel A 0.039 0.2099 0.5726
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0045 0.014
Trypanosoma brucei pyruvate kinase 1 0.0037 0.014 0.1736
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0051 0.0563
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1533
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0049 0.0527
Brugia malayi Latrophilin receptor protein 2 0.0147 0.0747 0.2817
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0013 0.0009 0.0024
Plasmodium vivax proline--tRNA ligase, putative 0.015 0.0764 0.0764
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0009 0.0013
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0095 0.0463 0.5689
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.009 0.1071
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0115 0.0406
Treponema pallidum glycyl-tRNA synthetase 0.0014 0.0014 0.0002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0009 0.0024
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0212 0.269
Giardia lamblia Aspartyl-tRNA synthetase 0.0014 0.0014 0.0068
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0366 0.0998
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0128 0.0646 0.1499
Echinococcus granulosus lamin dm0 0.006 0.0269 0.0733
Schistosoma mansoni smad 0.0015 0.0016 0.0044
Echinococcus multilocularis transfer RNA-Gly 0.0013 0.0009 0.002
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0014 0.0073
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.014 0.05
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.0801 0.2975
Brugia malayi PHD-finger family protein 0.0024 0.0068 0.0228
Loa Loa (eye worm) MBCTL1 0.0053 0.0227 0.0832
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0115 0.0115
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.006 0.0681
Echinococcus granulosus pyruvate kinase 0.0019 0.004 0.0108
Schistosoma mansoni sugar transporter 0.006 0.0268 0.073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0009 0.0013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0113 0.0399
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0013 0.0009 0.0024
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0014 0.0014 0.0004
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0191 0.0522
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Schistosoma mansoni transient receptor potential channel 0.0404 0.2173 0.5929
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0009 0.0024
Schistosoma mansoni lamin 0.006 0.0269 0.0733
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.014 0.1736
Echinococcus granulosus Threonyl tRNA synthetase C 0.0024 0.0068 0.0184
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0083 0.0126
Brugia malayi hypothetical protein 0.006 0.0268 0.0987
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0347 0.3919
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0227 0.0619
Brugia malayi hypothetical protein 0.0074 0.0347 0.129
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Schistosoma mansoni hypothetical protein 0.0147 0.0747 0.2039
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.0104
Loa Loa (eye worm) hypothetical protein 0.0095 0.0463 0.1734
Leishmania major pyruvate kinase 0.0037 0.014 0.1736
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Leishmania major GTP-binding protein, putative 0.0021 0.0049 0.0527
Echinococcus multilocularis short transient receptor potential channel 6 0.0267 0.1415 0.3286
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.4307 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.1708 0.8356
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0026 0.006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0155 0.0414
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Echinococcus granulosus glycyl tRNA synthetase 0.0024 0.0068 0.0184
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0009 0.0024
Schistosoma mansoni smad1 5 8 and 0.0033 0.0118 0.0321
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0024 0.0068 0.0779
Trichomonas vaginalis chaperonin, putative 0.0027 0.0083 0.0361
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0254 0.134 0.5079
Mycobacterium ulcerans integral membrane transport protein 0.006 0.0268 0.321
Loa Loa (eye worm) hypothetical protein 0.0147 0.0747 0.2817
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0181 0.2287
Giardia lamblia Pyruvate kinase 0.0037 0.014 0.0684
Brugia malayi hypothetical protein 0.006 0.0268 0.0987
Onchocerca volvulus 0.006 0.0268 0.2763
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.01 0.0273
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0009 0.002
Plasmodium falciparum mitogen-activated protein kinase 2 0.0691 0.3766 0.3766
Brugia malayi MH1 domain containing protein 0.0018 0.0036 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Brugia malayi Smad1 0.0033 0.0118 0.0416
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0009 0.0024
Schistosoma mansoni Smad4 0.0015 0.0016 0.0044
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0029 0.0079
Loa Loa (eye worm) hypothetical protein 0.0074 0.0347 0.1289
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0131 0.066 0.2485
Trichomonas vaginalis glucose transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus intermediate filament protein 0.006 0.0269 0.0733
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0131 0.066 0.2485
Echinococcus granulosus solute carrier family 22 0.006 0.0268 0.073
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0155 0.1375
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus multilocularis calcium dependent protein kinase 0.0123 0.0615 0.1429
Trypanosoma cruzi histidyl-tRNA synthetase 0.0014 0.0014 0.0073
Toxoplasma gondii hypothetical protein 0.0013 0.0009 0.0013
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0115 0.0173
Schistosoma mansoni hypothetical protein 0.0282 0.1498 0.4087
Trypanosoma brucei unspecified product 0.0015 0.0015 0.0081
Plasmodium vivax calcium-dependent protein kinase, putative 0.0131 0.0661 0.0661
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0147 0.0747 0.1735
Schistosoma mansoni protein kinase 0.0131 0.066 0.1802
Echinococcus multilocularis peregrin 0.0032 0.0113 0.0262
Echinococcus multilocularis General substrate transporter 0.0368 0.1972 0.4579
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0016 0.008
Schistosoma mansoni hypothetical protein 0.0147 0.0747 0.2039
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0268 0.116
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.006 0.0268 0.321
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0488 0.1332
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0024 0.0068 0.0679
Schistosoma mansoni glucose transporter 0.006 0.0268 0.073
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0131 0.066 0.2485
Schistosoma mansoni 60S ribosomal protein L21 0.0013 0.0009 0.0024
Leishmania major hypothetical protein, conserved 0.0074 0.0347 0.4479
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0016 0.0044
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0115 0.1409
Schistosoma mansoni calcium-activated potassium channel 0.0013 0.0009 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0848 0.3677
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0051 0.0222
Plasmodium falciparum calcium-dependent protein kinase 4 0.0131 0.0661 0.0661
Echinococcus granulosus pyruvate kinase 0.0037 0.014 0.0381
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0009 0.0024
Entamoeba histolytica Ran family GTPase 0.0021 0.0049 0.0237
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0268 0.0987
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0024 0.0068 0.0224
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0059 0.016
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0013 0.0009 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Brugia malayi jmjC domain containing protein 0.0098 0.0477 0.1787
Loa Loa (eye worm) hypothetical protein 0.0046 0.0191 0.0696
Plasmodium falciparum calcium-dependent protein kinase 1 0.0131 0.0661 0.0661
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0464 0.2504 0.9517
Echinococcus granulosus sodium leak channel non selective protein 0.0013 0.0009 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0347 0.1173
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0347 0.0805
Trypanosoma cruzi hexose transporter, putative 0.0133 0.067 0.8756
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0488 0.1332
Giardia lamblia Prolyl-tRNA synthetase 0.0128 0.0646 0.3158
Loa Loa (eye worm) latrophilin receptor protein 2 0.0147 0.0747 0.2817
Echinococcus multilocularis Sugar transporter ERD6 protein 0.006 0.0268 0.0621
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0059 0.0136
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.0009 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Echinococcus granulosus peregrin 0.0032 0.0113 0.0308
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.004 0.004
Brugia malayi Aspartyl-tRNA synthetase 0.0014 0.0014 0.002
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.015 0.0764 1
Trypanosoma brucei ISWI complex protein 0.0015 0.0017 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.067 0.2904
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0347 0.0947
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0488 0.1332
Schistosoma mansoni glucose transport protein 0.0428 0.2306 0.6291
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0115 0.1409
Schistosoma mansoni transient receptor potential channel 0.0267 0.1415 0.3861
Plasmodium vivax hexose transporter 0.0428 0.2306 0.2306
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0128 0.0297
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0009 0.0024
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0009 0.0024
Loa Loa (eye worm) intermediate filament protein 0.006 0.0269 0.0992
Echinococcus granulosus GPCR family 2 0.0147 0.0747 0.2039
Schistosoma mansoni intermediate filament proteins 0.006 0.0269 0.0733
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0009 0.002
Brugia malayi MH1 domain containing protein 0.0033 0.0118 0.0416
Loa Loa (eye worm) hypothetical protein 0.0317 0.1691 0.6416
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0992
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0347 0.4212
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0848 0.8956
Echinococcus multilocularis pyruvate kinase 0.0037 0.014 0.0325
Plasmodium falciparum pyruvate kinase 2 0.0019 0.004 0.004
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0691 0.3766 0.3766
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0096 0.0261
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0009 0.002
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0024 0.0068 0.0679
Echinococcus multilocularis Smad4 0.0033 0.0118 0.0274
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0078 0.0379
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0049 0.0049
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0014 0.0014 0.0021
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0083 0.0988
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0049 0.0132
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0347 0.1173
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0013 0.0009 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0095 0.0463 0.6025
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0049 0.0113
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0009 0.0024
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.014 0.0351
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0347 0.1504
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Treponema pallidum fructose-bisphosphate aldolase 0.032 0.1708 1
Chlamydia trachomatis thioredoxin reductase 0.0157 0.0804 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Schistosoma mansoni DNA polymerase eta 0.0021 0.0051 0.014
Leishmania major glucose transporter, lmgt1 0.0133 0.067 0.8756
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0024 0.0068 0.0224
Plasmodium vivax pyruvate kinase, putative 0.0037 0.014 0.014
Onchocerca volvulus 0.006 0.0268 0.2763
Echinococcus multilocularis zinc finger protein 0.0019 0.004 0.0092
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0131 0.0661 0.0661
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.1327 0.5027
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0181 0.2119
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0009 0.002
Leishmania major glucose transporter, lmgt3 0.0133 0.067 0.8756
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0016 0.0028
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0477 0.1303
Schistosoma mansoni zinc finger protein 0.0015 0.0017 0.0045
Plasmodium vivax glycine--tRNA ligase, putative 0.0024 0.0068 0.0068
Mycobacterium ulcerans sugar transporter 0.006 0.0268 0.321
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0009 0.0024
Leishmania major myo-inositol/proton symporter (MIT) 0.006 0.0268 0.3429
Loa Loa (eye worm) hypothetical protein 0.0131 0.066 0.2485
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0066
Plasmodium falciparum protein kinase 7 0.1209 0.6635 0.6635
Echinococcus granulosus General substrate transporter 0.0368 0.1972 0.5381
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0014 0.0014 0.002
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0013 0.0009 0.0024
Leishmania major DNA polymerase eta, putative 0.0021 0.0051 0.0563
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0084 0.0398 0.1727
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.066 0.1802
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0218 0.08
Toxoplasma gondii aspartate-tRNA ligase 0.0014 0.0014 0.0021
Onchocerca volvulus 0.0074 0.0347 0.3608
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0089 0.0308
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0078 0.0262
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0083 0.0285
Echinococcus multilocularis calcium activated potassium channel 0.0022 0.0054 0.0126
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0157 0.0804 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0256 0.0699
Toxoplasma gondii glycyl-tRNA synthetase 0.0024 0.0068 0.0102
Echinococcus granulosus voltage dependent calcium channel 0.0013 0.0009 0.0024
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0115 0.0254
Trypanosoma brucei THT1 - hexose transporter, putative 0.0133 0.067 0.8756
Loa Loa (eye worm) nuclear factor I 0.0018 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0059 0.0263 0.0968
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.004 0.006
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0009 0.002
Schistosoma mansoni Smad4 0.0033 0.0118 0.0321
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0191 0.0522
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0128 0.0646 0.3158
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0131 0.066 0.1802
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0347 0.1173
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Loa Loa (eye worm) Smad1 0.0033 0.0118 0.0416
Mycobacterium ulcerans hypothetical protein 0.0021 0.0052 0.0482
Echinococcus granulosus zinc finger protein 0.0019 0.004 0.0108
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0115 0.0267
Echinococcus granulosus lysyl tRNA synthetase 0.0095 0.0463 0.1265
Echinococcus multilocularis glycyl tRNA synthetase 0.0024 0.0068 0.0157
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0009 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0015 0.0081
Loa Loa (eye worm) hypothetical protein 0.004 0.0154 0.0553
Echinococcus multilocularis histidyl tRNA synthetase 0.0014 0.0014 0.0033
Plasmodium falciparum calcium-dependent protein kinase 5 0.0131 0.0661 0.0661
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0181 0.0273
Giardia lamblia DINP protein human, muc B family 0.0021 0.0051 0.0251
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0014 0.0014 0.0073
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni sugar transporter 0.006 0.0268 0.073
Echinococcus granulosus voltage dependent calcium channel 0.0013 0.0009 0.0024
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0051 0.0251
Echinococcus multilocularis pyruvate kinase 0.0019 0.004 0.0092
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0081 0.0384 0.441
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Schistosoma mansoni pyruvate kinase 0.0037 0.014 0.0381
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Chlamydia trachomatis lysine--tRNA ligase 0.0095 0.0463 0.5689
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0013 0.0009 0.0024
Leishmania major hypothetical protein, conserved 0.0015 0.0017 0.0104
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0052 0.0573
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.067 0.2904
Leishmania major threonyl-tRNA synthetase, putative 0.0024 0.0068 0.0779
Echinococcus multilocularis potassium large conductance calcium activated 0.0013 0.0009 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0026 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0347 0.4479
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.005 0.0212 0.0774
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0009 0.0024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0026 0.0071
Brugia malayi MH2 domain containing protein 0.0033 0.0118 0.0416
Leishmania major aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Giardia lamblia Glycyl-tRNA synthetase 0.0024 0.0068 0.033
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.0764 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0095 0.0463 0.1265
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0131 0.0661 0.0661
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0477 0.1108
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0128 0.0646 0.2429
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0051 0.0162
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0181 0.0887
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0049 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0165 0.0383
Echinococcus granulosus synaptic vesicle 2 protein 0.006 0.0268 0.073
Echinococcus granulosus dna polymerase kappa 0.0021 0.0051 0.014
Brugia malayi Transient-receptor-potential like protein 0.015 0.0767 0.2891
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.006 0.0268 0.0859
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0428 0.2306 0.5354
Loa Loa (eye worm) hypothetical protein 0.0053 0.0227 0.0832
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0181 0.2287
Loa Loa (eye worm) hypothetical protein 0.015 0.0767 0.2891
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0021 0.0052 0.0573
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0347 0.1289
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Loa Loa (eye worm) hypothetical protein 0.0137 0.0692 0.2607
Brugia malayi hypothetical protein 0.0032 0.0113 0.0399
Loa Loa (eye worm) hypothetical protein 0.0128 0.0646 0.2429
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0009 0.0013
Onchocerca volvulus 0.006 0.0268 0.2763
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0227 0.0832
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0115 0.0314
Trypanosoma cruzi sugar transporter, putative 0.006 0.0268 0.3429
Echinococcus multilocularis two pore calcium channel protein 2 0.0013 0.0009 0.002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0233 0.1226 0.4643
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0009 0.0024
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0009 0.002
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0024 0.0068 0.033
Brugia malayi mbt repeat family protein 0.0046 0.0191 0.0696
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0348
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0262
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0268 0.0987
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0347 0.4479
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Brugia malayi Bromodomain containing protein 0.0032 0.0113 0.0397
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.0104
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0009 0.002
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0024 0.0068 0.0679
Echinococcus multilocularis solute carrier family 22 0.006 0.0268 0.0621
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.014 0.0606
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Echinococcus granulosus histidyl tRNA synthetase 0.0014 0.0014 0.0039
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0131 0.0661 0.0661
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0051 0.0119
Schistosoma mansoni ryanodine receptor related 0.0014 0.0009 0.0025
Plasmodium falciparum threonine--tRNA ligase 0.0024 0.0068 0.0068
Echinococcus granulosus short transient receptor potential channel 6 0.0267 0.1415 0.3861
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0051 0.014
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0014 0.0014 0.0068
Mycobacterium tuberculosis Conserved protein 0.0074 0.0347 0.1173
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0191 0.0444
Leishmania major histidyl-tRNA synthetase, putative 0.0014 0.0014 0.0073
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0013 0.0009 0.002
Onchocerca volvulus 0.006 0.0269 0.2775
Plasmodium vivax hypothetical protein, conserved 0.003 0.01 0.01
Plasmodium falciparum phd finger protein, putative 0.003 0.01 0.01
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0056 0.0152
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.014 0.1399
Trypanosoma brucei sugar transporter, putative 0.006 0.0268 0.3429
Brugia malayi Sugar transporter family protein 0.0428 0.2306 0.8761
Loa Loa (eye worm) hypothetical protein 0.0128 0.0646 0.2429
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0009 0.0013
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0083 0.0227
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0009 0.0038
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Schistosoma mansoni protein kinase 0.0131 0.066 0.1802
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0009 0.0024
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.015 0.0764 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0268 0.0987
Schistosoma mansoni inositol monophosphatase 0.0045 0.0181 0.0495
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0009 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Schistosoma mansoni hypothetical protein 0.0074 0.0347 0.0947
Brugia malayi jmjC domain containing protein 0.0038 0.0145 0.052
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0347 0.1504
Toxoplasma gondii hypothetical protein 0.0013 0.0009 0.0013
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.01 0.0151
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0016 0.0028
Echinococcus multilocularis musashi 0.006 0.0269 0.0624
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0268 0.0987
Schistosoma mansoni hypothetical protein 0.0428 0.2306 0.6291
Leishmania major glycyl tRNA synthetase, putative 0.0014 0.0014 0.0073
Schistosoma mansoni aspartyl-tRNA synthetase 0.0014 0.0014 0.0038
Echinococcus multilocularis voltage dependent calcium channel 0.0013 0.0009 0.002
Echinococcus multilocularis solute carrier family 22 0.006 0.0268 0.0621
Leishmania major lysyl-tRNA synthetase, putative 0.0095 0.0463 0.6025
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2306 0.6291
Schistosoma mansoni hypothetical protein 0.0147 0.0747 0.2039
Echinococcus multilocularis smad 0.0033 0.0118 0.0274
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0212 0.0212
Plasmodium vivax asparagine--tRNA ligase, putative 0.0014 0.0014 0.0014
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0083 0.0227
Brugia malayi hypothetical protein 0.0182 0.0946 0.3573
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1327 0.5754
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.1708 0.7408
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Mycobacterium ulcerans pyruvate kinase 0.0037 0.014 0.1593
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0016 0.0038
Trypanosoma brucei glucose transporter, putative 0.0133 0.067 0.8756
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0049 0.0237
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0181 0.2119
Mycobacterium tuberculosis Conserved protein 0.0074 0.0347 0.1173
Chlamydia trachomatis threonine--tRNA ligase 0.0024 0.0068 0.0679
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0115 0.0267
Trypanosoma cruzi hexose transporter, putative 0.0133 0.067 0.8756
Entamoeba histolytica protein kinase, putative 0.0131 0.066 0.323
Echinococcus granulosus two pore calcium channel protein 2 0.0013 0.0009 0.0024
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.006 0.0268 0.321
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.006 0.0268 0.073
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0691 0.3766 0.5677
Schistosoma mansoni glycyl-tRNA synthetase 0.0024 0.0068 0.0184
Entamoeba histolytica hypothetical protein 0.0108 0.0534 0.2615
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0083 0.0227
Echinococcus granulosus solute carrier family 22 0.006 0.0268 0.073
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0083 0.0361
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0009 0.0024
Echinococcus multilocularis geminin 0.0673 0.3665 0.851
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0009 0.0024
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0051 0.0563
Echinococcus multilocularis muscleblind protein 1 0.0164 0.0841 0.1952
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0051 0.0563
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0227 0.0619
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.014 0.0211
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0014 0.0014 0.0021
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0014 0.0009 0.0002
Onchocerca volvulus 0.006 0.0268 0.2763
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0096 0.0222
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0428 0.2306 0.6291
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.066 0.1533
Schistosoma mansoni zinc finger protein 0.0019 0.004 0.0108
Leishmania major hypothetical protein, conserved 0.005 0.0212 0.269
Trichomonas vaginalis sugar transporter, putative 0.006 0.0268 0.116
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0009 0.002
Onchocerca volvulus Alhambra homolog 0.003 0.01 0.0974
Echinococcus granulosus two pore calcium channel protein 1 0.0013 0.0009 0.0024

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 999 um PUBCHEM_BIOASSAY: Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase. (Class of assay: confirmatory) [Related pubchem assays: 518 ] ChEMBL. No reference
IC50 (functional) = 78.3 um PUBCHEM_BIOASSAY: Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase. (Class of assay: confirmatory) [Related pubchem assays: 1512, 518 ] ChEMBL. No reference
Potency (functional) 2.3323 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 32.6427 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.