Detailed information for compound 1350277

Basic information

Technical information
  • TDR Targets ID: 1350277
  • Name: N-[(2-chlorophenyl)methyl]-3-[1-[2-[(2,6-dime thylphenyl)amino]-2-oxoethyl]-2,4-dioxothieno [3,2-d]pyrimidin-3-yl]propanamide
  • MW: 525.019 | Formula: C26H25ClN4O4S
  • H donors: 2 H acceptors: 4 LogP: 3.83 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(CCn1c(=O)c2sccc2n(c1=O)CC(=O)Nc1c(C)cccc1C)NCc1ccccc1Cl
  • InChi: 1S/C26H25ClN4O4S/c1-16-6-5-7-17(2)23(16)29-22(33)15-31-20-11-13-36-24(20)25(34)30(26(31)35)12-10-21(32)28-14-18-8-3-4-9-19(18)27/h3-9,11,13H,10,12,14-15H2,1-2H3,(H,28,32)(H,29,33)
  • InChiKey: ARLOQRQBSZFSPO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(2-chlorophenyl)methyl]-3-[1-[2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-2,4-dioxo-thieno[3,2-d]pyrimidin-3-yl]propanamide
  • N-[(2-chlorophenyl)methyl]-3-[1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-2,4-dioxo-3-thieno[3,2-d]pyrimidinyl]propanamide
  • N-(2-chlorobenzyl)-3-[1-[2-[(2,6-dimethylphenyl)amino]-2-keto-ethyl]-2,4-diketo-thieno[3,2-d]pyrimidin-3-yl]propionamide
  • NCGC00105950-01
  • C241-2077

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK protein kinase 0.0507 0.0478 0.0478
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0412 0.0327 0.0327
Brugia malayi Prion-like- 0.0247 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.1036 0.1325 0.1325
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.027 0.0099 0.0099
Brugia malayi serine/threonine kinase 12 0.0988 0.1248 0.1248
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0988 0.1248 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0506 0.0477 0.049
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.111 0.1442 0.1492
Echinococcus granulosus casein kinase i 0.0474 0.0427 0.0431
Echinococcus multilocularis c src tyrosine kinase 0.0605 0.0635 0.0654
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0356 0.0237 0.0855
Entamoeba histolytica protein kinase domain containing protein 0.0863 0.1048 0.4238
Entamoeba histolytica protein kinase, putative 0.0409 0.0322 0.129
Loa Loa (eye worm) SH2 domain-containing protein 0.021 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0443 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0385 0.0283 0.0289
Entamoeba histolytica protein kinase domain containing protein 0.0907 0.1119 0.4528
Brugia malayi Protein kinase domain containing protein 0.0907 0.1119 0.1119
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0955 0.1194 0.1212
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis tyrosine protein kinase shark 0.0687 0.0767 0.0791
Echinococcus multilocularis tyrosine kinase 0.0232 0.004 0.0036
Entamoeba histolytica cysteine surface protein, putative 0.0232 0.004 0.0142
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0281 0.0118 0.0117
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0253 0.0072 0.0072
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0955 0.1194 0.1235
Brugia malayi Protein kinase domain containing protein 0.0212 0.0007 0.0007
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0907 0.1119 0.4449
Loa Loa (eye worm) TK protein kinase 0.0232 0.004 0.004
Echinococcus multilocularis roundabout 2 0.0281 0.0118 0.0117
Echinococcus multilocularis tyrosine protein kinase 0.0507 0.0478 0.0491
Trichomonas vaginalis STE family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0232 0.004 0.0142
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.636 0.9833 1
Trichomonas vaginalis CAMK family protein kinase 0.0242 0.0056 0.0189
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0232 0.004 0.0068
Brugia malayi MAP kinase sur-1 0.0475 0.0427 0.0427
Echinococcus granulosus protein tyrosine kinase 0.1074 0.1385 0.1406
Echinococcus granulosus serine:threonine protein kinase MARK2 0.111 0.1442 0.1464
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0564 0.057 0.0587
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0481 0.0437 0.1723
Schistosoma mansoni vesicular amine transporter 0.0523 0.0504 0.0972
Entamoeba histolytica PH domain containing protein kinase, putative 0.0986 0.1245 0.504
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.2471 0.3618 0.3751
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0237 0.0048 0.0035
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0302 0.0152 0.0461
Schistosoma mansoni hypothetical protein 0.0232 0.004 0.0068
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Echinococcus granulosus protein kinase C gamma type 0.1175 0.1547 0.157
Loa Loa (eye worm) hypothetical protein 0.0523 0.0504 0.0504
Brugia malayi Protein kinase domain containing protein 0.1637 0.2285 0.2285
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0411 0.0326 0.0326
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0776 0.0909 0.0909
Toxoplasma gondii diacylglycerol kinase, putative 0.0245 0.0059 0.0083
Entamoeba histolytica PH domain containing protein kinase, putative 0.0986 0.1245 0.504
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1674 0.2344 0.2344
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0237 0.0048 0.0084
Onchocerca volvulus 0.0863 0.1048 0.2141
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0745 0.0859 0.0859
Brugia malayi Immunoglobulin I-set domain containing protein 0.0272 0.0103 0.0103
Schistosoma mansoni protein kinase 0.0331 0.0198 0.0376
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0232 0.004 0.0124
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0988 0.1248 0.5054
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.0295 0.0564
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0174 0.0329
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1524 0.2105 0.4312
Brugia malayi P38 map kinase family protein 2 0.109 0.1411 0.1411
Onchocerca volvulus 0.0443 0.0376 0.0762
Entamoeba histolytica protein kinase domain containing protein 0.0342 0.0216 0.0857
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0232 0.004 0.004
Brugia malayi P21-Rho-binding domain containing protein 0.0218 0.0017 0.0017
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0475 0.0427 0.1682
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Echinococcus multilocularis growth factor receptor bound protein 2 0.0373 0.0264 0.0269
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.021 0.0005 0.0002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0517 0.0496 0.0955
Plasmodium vivax protein kinase, putative 0.0276 0.011 0.058
Entamoeba histolytica protein kinase, putative 0.0385 0.0283 0.1132
Echinococcus multilocularis casein kinase ii subunit alpha 0.058 0.0596 0.0613
Trichomonas vaginalis TKL family protein kinase 0.0233 0.0041 0.0127
Onchocerca volvulus 0.0443 0.0376 0.0762
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1619 0.2256 0.2256
Entamoeba histolytica tyrosin kinase, putative 0.026 0.0084 0.0323
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.109 0.1411 0.5951
Echinococcus multilocularis lachesin 0.0247 0.0063 0.006
Entamoeba histolytica protein kinase, putative 0.0393 0.0296 0.1184
Brugia malayi hypothetical protein 0.0557 0.0559 0.0559
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni nephrin 0.0281 0.0118 0.0219
Loa Loa (eye worm) hypothetical protein 0.0385 0.0283 0.0283
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Onchocerca volvulus 0.0443 0.0376 0.0762
Schistosoma mansoni serine/threonine protein kinase 0.1875 0.2666 0.518
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0223 0.0025 0.002
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus epidermal growth factor receptor 0.2234 0.324 0.3293
Schistosoma mansoni cell adhesion molecule 0.0281 0.0118 0.0219
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.154 0.213 0.4136
Schistosoma mansoni neuroglian 0.0281 0.0118 0.0219
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.004 0.0037
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0955 0.1194 0.1212
Brugia malayi Protein kinase domain containing protein 0.067 0.074 0.074
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0942 0.1174 0.1214
Brugia malayi C-terminal src kinase protein 1 0.0232 0.004 0.004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.021 0.0005 0.0005
Loa Loa (eye worm) TK/CSK protein kinase 0.0232 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Leishmania major protein kinase A catalytic subunit 0.0535 0.0523 0.2096
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0232 0.004 0.0036
Trypanosoma cruzi casein kinase, putative 0.0474 0.0427 0.1678
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0474 0.0427 0.1678
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0261 0.0086 0.0086
Brugia malayi tRNA modification GTPase TrmE family protein 0.021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.1036 0.1325 0.1325
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.058 0.0596 0.0596
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0268 0.0097 0.0096
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Trichomonas vaginalis STE family protein kinase 0.0506 0.0477 0.1903
Plasmodium vivax glycogen synthase kinase 3, putative 0.0863 0.1048 0.834
Entamoeba histolytica protein kinase, putative 0.175 0.2465 1
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0247 0.0063 0.0119
Brugia malayi Fes/CIP4 homology domain containing protein 0.0249 0.0066 0.0066
Brugia malayi Protein kinase domain containing protein 0.0404 0.0315 0.0315
Echinococcus multilocularis Immunoglobulin 0.0523 0.0504 0.0518
Echinococcus multilocularis cyclin dependent kinase 19 0.0284 0.0123 0.0122
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0506 0.0477 0.0482
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Echinococcus granulosus titin 0.0309 0.0163 0.0163
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0475 0.0427 0.1682
Echinococcus granulosus tyrosine kinase 0.0792 0.0935 0.0948
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0385 0.0283 0.1033
Plasmodium vivax serine/threonine kinase-1, putative 0.0412 0.0326 0.237
Brugia malayi Protein kinase domain containing protein 0.1271 0.17 0.17
Echinococcus multilocularis cyclin dependent kinase 1 0.0745 0.0859 0.0887
Echinococcus multilocularis cyclin dependent kinase 5 0.0745 0.0859 0.0887
Echinococcus granulosus casein kinase I delta 0.0474 0.0427 0.0431
Schistosoma mansoni unc-13 (munc13) 0.0253 0.0072 0.0131
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Giardia lamblia Kinase, CAMK CAMKL 0.0364 0.025 0.103
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0475 0.0427 0.1702
Loa Loa (eye worm) hypothetical protein 0.0769 0.0898 0.0898
Entamoeba histolytica protein kinase, putative 0.1707 0.2397 0.9721
Echinococcus multilocularis serine:threonine protein kinase 38 0.0912 0.1126 0.1164
Entamoeba histolytica protein kinase, putative 0.046 0.0404 0.1622
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0506 0.0477 0.0482
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0381 0.0277 0.0977
Trichomonas vaginalis STE family protein kinase 0.0366 0.0254 0.0995
Echinococcus granulosus casein kinase I delta 0.0474 0.0427 0.0431
Echinococcus multilocularis hemicentin 1 0.0247 0.0063 0.006
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0535 0.0523 0.0523
Loa Loa (eye worm) TK/DDR protein kinase 0.0232 0.004 0.004
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0797 0.0943 0.0943
Loa Loa (eye worm) IKK protein kinase 0.1637 0.2285 0.2285
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Echinococcus granulosus NCK adaptor protein 0.0373 0.0264 0.0266
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.004 0.0037
Onchocerca volvulus 0.0903 0.1112 0.2272
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0232 0.004 0.0124
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0356 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis casein kinase I delta 0.0474 0.0427 0.0438
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0268 0.0097 0.0097
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0475 0.0427 0.1598
Echinococcus granulosus serine:threonine protein kinase 0.067 0.074 0.0749
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0745 0.0859 0.0859
Schistosoma mansoni protein kinase 0.0223 0.0025 0.0038
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Trichomonas vaginalis CK1 family protein kinase 0.0474 0.0427 0.1698
Brugia malayi Furin-like cysteine rich region family protein 0.3424 0.5142 0.5142
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis serine threonine protein kinase 0.1175 0.1547 0.1601
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.004 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.109 0.1411 0.5951
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0232 0.004 0.0124
Echinococcus multilocularis peroxidasin 0.0248 0.0066 0.0063
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0265 0.0091 0.0219
Trypanosoma brucei aurora B kinase 0.0988 0.1248 0.4983
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0412 0.0326 0.1243
Schistosoma mansoni protein kinase 0.0881 0.1077 0.2086
Echinococcus multilocularis serine:threonine protein kinase N2 0.106 0.1363 0.141
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.058 0.0596 0.4599
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0288 0.0128 0.0128
Onchocerca volvulus 0.1036 0.1325 0.271
Trichomonas vaginalis STE family protein kinase 0.0302 0.0152 0.0578
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0496 0.0462 0.0462
Leishmania major protein kinase, putative 0.0381 0.0277 0.1028
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0385 0.0283 0.2015
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0881 0.1077 0.1113
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0232 0.004 0.0037
Onchocerca volvulus Serine\/threonine kinase homolog 0.1674 0.2344 0.4804
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0232 0.004 0.0036
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0863 0.1048 0.1063
Trypanosoma cruzi casein kinase, putative 0.0474 0.0427 0.1678
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.004 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.1165 0.153 0.2968
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.1419 0.1937 0.3762
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.1194 0.1235
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0506 0.0477 0.049
Echinococcus granulosus Protein kinase C brain isozyme 0.1419 0.1937 0.1968
Echinococcus multilocularis casein kinase I alpha 0.0474 0.0427 0.0438
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0529
Entamoeba histolytica protein kinase, putative 0.0582 0.0599 0.2413
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Schistosoma mansoni hypothetical protein 0.044 0.0371 0.0713
Onchocerca volvulus 0.0232 0.004 0.0072
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0232 0.004 0.0037
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0412 0.0326 0.1181
Loa Loa (eye worm) TK/FAK protein kinase 0.1084 0.1401 0.1401
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0506 0.0477 0.0482
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0237 0.0048 0.0035
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0907 0.1119 0.1119
Echinococcus multilocularis mitogen activated protein kinase 3 0.0475 0.0427 0.0439
Leishmania major casein kinase, putative 0.0474 0.0427 0.1678
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0943 0.1176 0.9404
Entamoeba histolytica cell division protein kinase 2, putative 0.0753 0.0872 0.3524
Loa Loa (eye worm) hypothetical protein 0.0658 0.0721 0.0721
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Onchocerca volvulus 0.0326 0.019 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni tyrosine kinase 0.161 0.2242 0.4354
Brugia malayi SH2 domain containing protein 0.079 0.0931 0.0931
Trypanosoma cruzi cdc2-related kinase 3 0.0745 0.0859 0.3554
Onchocerca volvulus 0.0232 0.004 0.0072
Schistosoma mansoni cell adhesion molecule 0.0247 0.0063 0.0112
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0455 0.0396 0.0761
Echinococcus multilocularis activated cdc42 kinase 1 0.0404 0.0315 0.0322
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0443 0.0376 0.1509
Schistosoma mansoni vav2 0.0498 0.0464 0.0894
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1707 0.2397 0.2397
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0385 0.0283 0.1033
Schistosoma mansoni serine/threonine protein kinase 0.0561 0.0565 0.1091
Trypanosoma cruzi casein kinase II, putative 0.058 0.0596 0.2412
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0868 0.1055 0.109
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0118 0.0118
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.109 0.1411 0.5654
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis TGF beta receptor type 1 0.0223 0.0025 0.002
Schistosoma mansoni tyrosine kinase 0.2234 0.324 0.6297
Echinococcus granulosus SHC transforming protein 3 0.021 0.0005 0.0002
Brugia malayi ephrin receptor 1 precursor 0.0426 0.035 0.035
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1051 0.1349 0.1349
Schistosoma mansoni hypothetical protein 0.0237 0.0048 0.0084
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0242 0.0056 0.0054
Schistosoma mansoni protein kinase 0.0366 0.0254 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.004 0.0068
Entamoeba histolytica hypothetical protein 0.0218 0.0017 0.0049
Entamoeba histolytica protein kinase, putative 0.0988 0.1248 0.5054
Onchocerca volvulus 0.2178 0.315 0.6459
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Brugia malayi Doublecortin family protein 0.0283 0.0121 0.0121
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus PAK box P21 Rho binding 0.0218 0.0017 0.0014
Echinococcus granulosus neuroglian 0.0281 0.0118 0.0117
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.067 0.074 0.074
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0232 0.004 0.0068
Echinococcus granulosus calcium dependent protein kinase 0.0236 0.0046 0.0044
Echinococcus multilocularis epidermal growth factor receptor 0.3424 0.5142 0.5333
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0412 0.0326 0.1181
Entamoeba histolytica hypothetical protein, conserved 0.0232 0.004 0.0142
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0385 0.0283 0.0289
Schistosoma mansoni protein kinase 0.0881 0.1077 0.2086
Echinococcus granulosus protein kinase c iota type 0.1689 0.2369 0.2407
Loa Loa (eye worm) hypothetical protein 0.1036 0.1325 0.1325
Brugia malayi Immunoglobulin I-set domain containing protein 0.0557 0.0559 0.0559
Brugia malayi Receptor family ligand binding region containing protein 0.0232 0.004 0.004
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.154 0.213 0.2164
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1674 0.2344 1
Echinococcus multilocularis neuroglian 0.0281 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0237 0.0048 0.0048
Brugia malayi hypothetical protein 0.0237 0.0048 0.0048
Echinococcus granulosus nervana 2 0.0795 0.0939 0.0953
Loa Loa (eye worm) TK/ROR protein kinase 0.0359 0.0242 0.0242
Brugia malayi Fibronectin type III domain containing protein 0.0557 0.0559 0.0559
Echinococcus granulosus casein kinase I alpha 0.0474 0.0427 0.0431
Giardia lamblia Kinase, NEK 0.0919 0.1137 0.4829
Schistosoma mansoni titin 0.0247 0.0063 0.0112
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi Protein kinase domain containing protein 0.0935 0.1163 0.1163
Trichomonas vaginalis AGC family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0455 0.0396 0.0396
Schistosoma mansoni protein kinase 0.0307 0.0159 0.0299
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0359 0.0242 0.0963
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.004 0.0036
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1674 0.2344 0.2429
Schistosoma mansoni hypothetical protein 0.0218 0.0017 0.0023
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0535 0.0523 0.1992
Schistosoma mansoni serine/threonine protein kinase 0.1419 0.1937 0.3762
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0475 0.0427 0.1682
Brugia malayi p70 ribosomal S6 kinase beta 0.1707 0.2397 0.2397
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0412 0.0326 0.1243
Brugia malayi Protein kinase domain 0.0506 0.0477 0.0477
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni protein kinase 0.0506 0.0477 0.0918
Loa Loa (eye worm) TK protein kinase 0.0579 0.0595 0.0595
Echinococcus granulosus SH2 domain containing protein 7 0.021 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0797 0.0943 0.0943
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Leishmania major protein kinase A catalytic subunit isoform 1 0.0535 0.0523 0.2096
Entamoeba histolytica protein kinase, putative 0.0366 0.0254 0.1012
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1401 0.1908 0.1908
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Trypanosoma cruzi cdc2-related kinase 1 0.0745 0.0859 0.3554
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0455 0.0396 0.04
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.027 0.0099 0.0099
Onchocerca volvulus 0.0232 0.004 0.0072
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0745 0.0859 0.0859
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0935 0.1163 0.4699
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) TK protein kinase 0.0232 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0326 0.0626
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus peroxidasin 0.0248 0.0066 0.0064
Echinococcus multilocularis dual specificity protein kinase clk2 0.0412 0.0326 0.0334
Schistosoma mansoni protein kinase C 0.0253 0.0072 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0745 0.0859 0.3459
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0381 0.0277 0.1005
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0474 0.0427 0.0427
Schistosoma mansoni protein kinase 0.0585 0.0604 0.1167
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0392 0.0295 0.0297
Brugia malayi diacylglycerol kinase 0.0245 0.0059 0.0059
Plasmodium falciparum NIMA related kinase 1 0.0919 0.1137 0.9078
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Echinococcus granulosus suppressor of cytokine signaling 7 0.021 0.0005 0.0002
Trichomonas vaginalis STE family protein kinase 0.0506 0.0477 0.1903
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0373 0.0264 0.0264
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0356 0.0237 0.0855
Schistosoma mansoni serine/threonine protein kinase 0.1075 0.1387 0.2691
Loa Loa (eye worm) AGC/AKT protein kinase 0.175 0.2465 0.2465
Loa Loa (eye worm) hypothetical protein 0.0253 0.0074 0.0074
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0919 0.1137 0.4655
Entamoeba histolytica hypothetical protein 0.0245 0.0059 0.0221
Brugia malayi hypothetical protein 0.0561 0.0565 0.0565
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0392 0.0295 0.0301
Echinococcus granulosus integrin linked protein kinase 0.0232 0.004 0.0037
Giardia lamblia Kinase, NEK 0.0232 0.004 0.013
Echinococcus granulosus kinase suppressor of Ras 1 0.0232 0.004 0.0037
Schistosoma mansoni growth factor receptor-bound protein 0.0373 0.0264 0.0504
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0561 0.0565 0.0572
Entamoeba histolytica hypothetical protein 0.0234 0.0043 0.0154
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0935 0.1163 0.1163
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0298 0.0145 0.0145
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) TK protein kinase 0.0232 0.004 0.004
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1875 0.2666 0.2666
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.1674 0.2344 0.4554
Brugia malayi Protein kinase domain containing protein 0.0797 0.0943 0.0943
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Brugia malayi Protein kinase domain containing protein 0.1084 0.1401 0.1401
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1401 0.1908 0.1975
Onchocerca volvulus Serine\/threonine kinase homolog 0.0298 0.0145 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0468 0.0417 0.166
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni serine/threonine RGC 0.0232 0.004 0.0068
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0331 0.0198 0.0198
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.027 0.0099 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0431 0.0829
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0919 0.1137 0.9078
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0091 0.0168
Brugia malayi Guanylyl cyclase protein 23 0.0232 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0612 0.0647 0.125
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1075 0.1387 0.1387
Giardia lamblia Kinase, AGC PKA 0.0535 0.0523 0.2199
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0903 0.1112 0.1112
Trypanosoma cruzi cdc2-related kinase 1 0.0745 0.0859 0.3554
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0863 0.1048 0.4276
Echinococcus multilocularis aurora kinase A 0.0988 0.1248 0.1291
Entamoeba histolytica protein kinase domain containing protein 0.058 0.0596 0.2401
Trichomonas vaginalis CMGC family protein kinase 0.0475 0.0427 0.1702
Entamoeba histolytica protein kinase, putative 0.0392 0.0295 0.1178
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.067 0.074 0.074
Echinococcus multilocularis FL cytokine receptor 0.0232 0.004 0.0036
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0245 0.0059 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0145 0.0273
Entamoeba histolytica hypothetical protein 0.0234 0.0043 0.0154
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0912 0.1126 0.1164
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0745 0.0859 0.3554
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Schistosoma mansoni serine/threonine-protein kinase 0.0986 0.1245 0.2414
Plasmodium falciparum calcium-dependent protein kinase 1 0.0385 0.0283 0.2015
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0255 0.0076 0.0074
Trichomonas vaginalis CMGC family protein kinase 0.0863 0.1048 0.4228
Trichomonas vaginalis CMGC family protein kinase 0.0745 0.0859 0.3459
Brugia malayi SH2 domain containing protein 0.0443 0.0376 0.0376
Plasmodium vivax unspecified product 0.058 0.0596 0.4599
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0356 0.0237 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0174 0.0329
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni atypical protein kinase C 0.1729 0.2431 0.4723
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Entamoeba histolytica receptor protein kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Brugia malayi Protein kinase domain containing protein 0.046 0.0404 0.0404
Trypanosoma brucei rac serine-threonine kinase, putative 0.175 0.2465 1
Loa Loa (eye worm) AGC/PKG protein kinase 0.0265 0.0091 0.0091
Entamoeba histolytica protein kinase 2, putative 0.0943 0.1176 0.4761
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0302 0.0152 0.0152
Plasmodium falciparum glycogen synthase kinase 3 0.0863 0.1048 0.834
Brugia malayi Protein kinase domain containing protein 0.0745 0.0859 0.0859
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.0128 0.024
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Trypanosoma brucei casein kinase I, isoform 2 0.0474 0.0427 0.1594
Loa Loa (eye worm) hypothetical protein 0.0557 0.0559 0.0559
Echinococcus granulosus twitchin 0.0798 0.0944 0.0957
Echinococcus multilocularis fibroblast growth factor receptor 4 0.161 0.2242 0.2322
Brugia malayi probable protein kinase 0.0585 0.0604 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0091 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0118 0.0118
Echinococcus granulosus hypothetical protein 0.0263 0.0089 0.0088
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Brugia malayi RhoGEF domain containing protein 0.0245 0.0059 0.0059
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0357 0.024 0.024
Loa Loa (eye worm) TK/ALK protein kinase 0.1271 0.1699 0.1699
Brugia malayi Protein kinase domain containing protein 0.175 0.2465 0.2465
Echinococcus multilocularis N chimaerin 0.0455 0.0396 0.0406
Loa Loa (eye worm) hypothetical protein 0.0281 0.0118 0.0118
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1753 0.2471 0.2511
Echinococcus granulosus cyclin dependent kinase 19 0.0284 0.0123 0.0122
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.004 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0381 0.0277 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.0863 0.1048 0.4238
Loa Loa (eye worm) hypothetical protein 0.0523 0.0504 0.0504
Schistosoma mansoni tyrosine kinase 0.045 0.0388 0.0746
Echinococcus multilocularis Immunoglobulin 0.0523 0.0504 0.0518
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0288 0.0128 0.0484
Trypanosoma cruzi casein kinase, putative 0.0474 0.0427 0.1678
Echinococcus multilocularis cyclin dependent kinase 7 0.0316 0.0174 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0943 0.1176 0.1194
Schistosoma mansoni septate junction protein 0.0247 0.0063 0.0112
Brugia malayi Protein kinase domain containing protein 0.0624 0.0666 0.0666
Loa Loa (eye worm) CDC7 protein kinase 0.0213 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.0283 0.0542
Echinococcus granulosus insulin growth factor 1 receptor beta 0.2483 0.3637 0.3696
Loa Loa (eye worm) hypothetical protein 0.0578 0.0592 0.0592
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.0237 0.0452
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0237 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0797 0.0943 0.0943
Echinococcus multilocularis tyrosine protein kinase Srms 0.0792 0.0935 0.0966
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0986 0.1245 0.523
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi Kinase associated domain 1 family protein 0.044 0.0371 0.0371
Schistosoma mansoni protein kinase 0.0881 0.1077 0.2086
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) TK/EPH protein kinase 0.0757 0.0878 0.0878
Brugia malayi Tyrosine-protein kinase abl-1 0.0558 0.056 0.056
Onchocerca volvulus 0.0309 0.0163 0.0325
Echinococcus granulosus activin receptor type 0.0761 0.0885 0.0897
Schistosoma mansoni tyrosine kinase 0.2002 0.2868 0.5574
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0385 0.0283 0.1004
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.004 0.004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.161 0.2242 0.2277
Trichomonas vaginalis protein kinase atn1, putative 0.0232 0.004 0.0124
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0247 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1346 0.182 0.1884
Trichomonas vaginalis AGC family protein kinase 0.0978 0.1232 0.4978
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0538
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni tyrosine kinase 0.0955 0.1194 0.2315
Brugia malayi hypothetical protein 0.0232 0.004 0.004
Echinococcus granulosus tyrosine protein kinase csk 0.0232 0.004 0.0037
Brugia malayi Protein kinase domain containing protein 0.0443 0.0376 0.0376
Echinococcus granulosus protein kinase 0.0348 0.0225 0.0226
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0342 0.0216 0.0216
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Brugia malayi map kinase activated protein kinase protein 2 0.2471 0.3618 0.3618
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.1194 0.1235
Echinococcus granulosus tyrosine kinase 0.0232 0.004 0.0037
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1051 0.1349 0.1349
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0624 0.0666 0.0666
Loa Loa (eye worm) CAMK protein kinase 0.0309 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0248 0.0066 0.0066
Loa Loa (eye worm) TK/Met protein kinase 0.0232 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Echinococcus granulosus NDR protein kinase 0.0912 0.1126 0.1143
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0385 0.0283 0.2015
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0759 0.0882 0.0882
Schistosoma mansoni protein kinase 0.0381 0.0277 0.0529
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0232 0.004 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.021 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Src42A 0.0955 0.1194 0.1212
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0392 0.0295 0.0297
Trichomonas vaginalis STE family protein kinase 0.0302 0.0152 0.0578
Echinococcus granulosus dual specificity 0.027 0.0099 0.0098
Loa Loa (eye worm) TK protein kinase 0.0582 0.0599 0.0599
Brugia malayi Tensin 0.021 0.0005 0.0005
Brugia malayi Tyrosine-protein kinase abl-1 0.095 0.1187 0.1187
Schistosoma mansoni serine/threonine protein kinase 0.0342 0.0216 0.0411
Echinococcus multilocularis mitogen activated protein kinase 11 0.109 0.1411 0.146
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.0237 0.0452
Trypanosoma cruzi p21-activated kinase 3, putative 0.0288 0.0128 0.0385
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.021 0.0005 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Echinococcus multilocularis protein kinase c iota type 0.1689 0.2369 0.2454
Entamoeba histolytica casein kinase, putative 0.0474 0.0427 0.1713
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0912 0.1126 0.2182
Loa Loa (eye worm) AGC/NDR protein kinase 0.0912 0.1126 0.1126
Echinococcus multilocularis serine:threonine protein kinase 3 0.1588 0.2206 0.2285
Trichomonas vaginalis CAMK family protein kinase 0.1682 0.2357 0.956
Echinococcus granulosus tyrosine protein kinase Src42A 0.0564 0.057 0.0577
Giardia lamblia Kinase, STE STE20 0.0481 0.0437 0.183
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1524 0.2105 0.2138
Plasmodium falciparum calcium-dependent protein kinase 2 0.0385 0.0283 0.2015
Trichomonas vaginalis AGC family protein kinase 0.0919 0.1137 0.4591
Entamoeba histolytica hypothetical protein 0.0218 0.0017 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0608 0.1175
Schistosoma mansoni rac gtpase activating protein 0.0245 0.0059 0.0106
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0218 0.0017 0.0014
Echinococcus granulosus roundabout 2 0.0281 0.0118 0.0117
Schistosoma mansoni protein kinase 0.0348 0.0225 0.0428
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0988 0.1248 0.5054
Schistosoma mansoni tyrosine kinase 0.2448 0.3582 0.6962
Trypanosoma cruzi polo-like protein kinase, putative 0.1674 0.2344 1
Brugia malayi Stress-activated protein kinase jnk-1 0.1875 0.2666 0.2666
Trichomonas vaginalis protein tyrosine kinase, putative 0.0232 0.004 0.0124
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0561 0.0565 0.0582
Echinococcus multilocularis roundabout 2 0.0281 0.0118 0.0117
Echinococcus granulosus activated cdc42 kinase 1 0.0404 0.0315 0.0317
Echinococcus multilocularis tyrosine protein kinase otk 0.0247 0.0063 0.006
Brugia malayi Protein kinase domain containing protein 0.1524 0.2105 0.2105
Brugia malayi intracellular kinase 0.0863 0.1048 0.1048
Echinococcus multilocularis casein kinase I alpha 0.0474 0.0427 0.0438
Brugia malayi protein kinase C II. 0.1165 0.153 0.153
Echinococcus granulosus cyclin dependent kinase 1 0.0745 0.0859 0.0871
Toxoplasma gondii CMGC kinase, CK2 family 0.058 0.0596 0.2358
Echinococcus granulosus MAP kinase activated protein kinase 2 0.2471 0.3618 0.3677
Schistosoma mansoni serine/threonine protein kinase 0.111 0.1442 0.2798
Schistosoma mansoni kinase 0.1793 0.2534 0.4923
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0385 0.0283 0.1033
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Entamoeba histolytica hypothetical protein 0.0907 0.1119 0.4528
Echinococcus granulosus c-Jun N-terminal kinases 0.1875 0.2666 0.2709
Onchocerca volvulus 0.0443 0.0376 0.0762
Entamoeba histolytica tyrosin kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Schistosoma mansoni protein kinase 0.0506 0.0477 0.0918
Echinococcus multilocularis tyrosine protein kinase pr2 0.0232 0.004 0.0036
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.0099 0.0259
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Loa Loa (eye worm) thyroid receptor interactor 0.0249 0.0066 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Echinococcus multilocularis epidermal growth factor receptor 0.2234 0.324 0.3358
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0412 0.0326 0.0326
Schistosoma mansoni protein kinase 0.1542 0.2132 0.4141
Brugia malayi Protein kinase domain containing protein 0.0213 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase shark 0.0687 0.0767 0.0777
Brugia malayi Protein kinase domain containing protein 0.0755 0.0875 0.0875
Onchocerca volvulus 0.0658 0.0721 0.147
Plasmodium falciparum casein kinase 2, alpha subunit 0.058 0.0596 0.4599
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0481 0.0437 0.1755
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Trichomonas vaginalis STE family protein kinase 0.0302 0.0152 0.0578
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0481 0.0437 0.1755
Brugia malayi WH1 domain containing protein 0.0218 0.0017 0.0017
Echinococcus multilocularis mitogen activated protein kinase 14 0.109 0.1411 0.146
Leishmania major casein kinase II, putative 0.058 0.0596 0.2412
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0475 0.0427 0.1682
Trichomonas vaginalis CAMK family protein kinase 0.0385 0.0283 0.1115
Echinococcus granulosus tensin 0.021 0.0005 0.0002
Brugia malayi Peroxidasin 0.0248 0.0066 0.0066
Brugia malayi Protein kinase domain containing protein 0.0507 0.0478 0.0478
Echinococcus granulosus TGF beta receptor type 1 0.0223 0.0025 0.0022
Leishmania major protein kinase, putative 0.0385 0.0283 0.1057
Plasmodium falciparum serine/threonine protein kinase KIN 0.0356 0.0237 0.1631
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus CDC7 cell division cycle 7 0.0213 0.0009 0.0007
Echinococcus granulosus dual specificity mitogen activated protein 0.0302 0.0152 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.004 0.0068
Brugia malayi Sex muscle abnormal protein 5 0.0373 0.0264 0.0264
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0232 0.004 0.0037
Trypanosoma cruzi casein kinase, putative 0.0474 0.0427 0.1678
Schistosoma mansoni diacylglycerol kinase theta 0.0245 0.0059 0.0106
Plasmodium falciparum casein kinase 1 0.0474 0.0427 0.3199
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus expressed conserved protein 0.021 0.0005 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) TK/FER protein kinase 0.079 0.0931 0.0931
Schistosoma mansoni serine/threonine protein kinase 0.046 0.0404 0.0777
Onchocerca volvulus Tyrosine kinase homolog 0.3257 0.4875 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Entamoeba histolytica ankyrin repeat protein 0.0232 0.004 0.0142
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1542 0.2132 0.2209
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0232 0.004 0.0068
Echinococcus multilocularis serine:threonine protein kinase 0.067 0.074 0.0763
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.154 0.213 0.2206
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.004 0.004
Echinococcus granulosus casein kinase I alpha 0.0474 0.0427 0.0431
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.1194 0.1212
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0535 0.0523 0.1992
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0819 0.0978 0.4071
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0009 0.0009
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0242 0.0056 0.0053
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0535 0.0523 0.3997
Onchocerca volvulus 0.0213 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.2178 0.315 0.6123
Brugia malayi serine/threonine-protein kinase PAK 7 0.1619 0.2256 0.2256
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0755 0.0875 0.0875
Brugia malayi integrin-linked kinase 0.0232 0.004 0.004
Onchocerca volvulus 0.0474 0.0427 0.0866
Brugia malayi Variant SH3 domain containing protein 0.0373 0.0264 0.0264
Loa Loa (eye worm) TK protein kinase 0.0232 0.004 0.004
Echinococcus multilocularis ephrin type A receptor 4 A 0.0644 0.0698 0.0719
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Schistosoma mansoni protein kinase 0.0988 0.1248 0.2421
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni hypothetical protein 0.0218 0.0017 0.0023
Giardia lamblia Kinase, CMGC CK2 0.058 0.0596 0.2511
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Echinococcus granulosus unc 13 munc13 0.0253 0.0072 0.0071
Echinococcus granulosus roundabout 2 0.0804 0.0953 0.0967
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0232 0.004 0.0036
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0309 0.0163 0.0163
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0412 0.0326 0.1216
Echinococcus multilocularis 0.0982 0.1238 0.128
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0326 0.019 0.065
Giardia lamblia Kinase, CK1 Casein kinase 0.0474 0.0427 0.1786
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Onchocerca volvulus 0.0412 0.0327 0.066
Onchocerca volvulus 0.0232 0.004 0.0072
Echinococcus granulosus SH2 motif 0.021 0.0005 0.0002
Echinococcus granulosus Diacylglycerol kinase theta 0.0245 0.0059 0.0057
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0863 0.1048 0.1048
Echinococcus granulosus hypothetical protein 0.021 0.0005 0.0002
Trypanosoma brucei SNF1-related protein kinases, putative 0.0356 0.0237 0.0813
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0281 0.0118 0.0117
Loa Loa (eye worm) AUR protein kinase 0.0988 0.1248 0.1248
Echinococcus multilocularis dual specificity 0.027 0.0099 0.0098
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0538
Brugia malayi C1-like domain containing protein 0.1051 0.1349 0.1349
Schistosoma mansoni roundabout 0.0247 0.0063 0.0112
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0218 0.0017 0.0023
Brugia malayi Protein kinase domain containing protein 0.0211 0.0005 0.0005
Echinococcus granulosus cGMP dependent protein kinase 1 0.0265 0.0091 0.009
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0481 0.0437 0.1637
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0356 0.0237 0.0813
Echinococcus granulosus serine threonine protein kinase nrc 0.0943 0.1176 0.1194
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0298 0.0145 0.0146
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0535 0.0523 0.205
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0235 0.0448
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus mitogen activated protein kinase 11 0.109 0.1411 0.1433
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0386 0.0285 0.0291
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0281 0.0118 0.0117
Brugia malayi Variant SH3 domain containing protein 0.0455 0.0396 0.0396
Schistosoma mansoni tyrosine kinase 0.2002 0.2868 0.5574
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0359 0.0242 0.0243
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0481 0.0437 0.1723
Toxoplasma gondii AGC kinase 0.0535 0.0523 0.205
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0792 0.0935 0.0948
Schistosoma mansoni tyrosine kinase 0.0687 0.0767 0.1483
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1524 0.2105 0.2105
Plasmodium vivax casein kinase 1, putative 0.0474 0.0427 0.3199
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0787 0.0927 0.3734
Echinococcus multilocularis casein kinase I delta 0.0474 0.0427 0.0438
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Loa Loa (eye worm) SRC-1 0.0955 0.1194 0.1194
Schistosoma mansoni serine/threonine protein kinase 0.0745 0.0859 0.1662
Echinococcus multilocularis raf serine:threonine protein kinase 0.0477 0.0431 0.0442
Giardia lamblia Protein 21.1 0.0232 0.004 0.013
Trichomonas vaginalis CMGC family protein kinase 0.0745 0.0859 0.3459
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0281 0.0118 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.1401 0.1908 0.3705
Loa Loa (eye worm) hypothetical protein 0.0658 0.0721 0.0721
Brugia malayi RhoGAP domain containing protein 0.0245 0.0059 0.0059
Schistosoma mansoni tyrosine kinase 0.3424 0.5142 1
Echinococcus granulosus SH2 domain containing adapter protein F 0.021 0.0005 0.0002
Brugia malayi Protein kinase domain containing protein 0.0331 0.0198 0.0198
Brugia malayi Protein kinase domain containing protein 0.0443 0.0376 0.0376
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni tyrosine kinase 0.0477 0.043 0.0828
Schistosoma mansoni serine/threonine protein kinase 0.0907 0.1119 0.2169
Loa Loa (eye worm) hypothetical protein 0.0535 0.0523 0.0523
Trichomonas vaginalis AGC family protein kinase 0.0988 0.1248 0.5045
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.0718 0.1387
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0475 0.0427 0.1682
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trypanosoma brucei Casein kinase II 0.058 0.0596 0.2292
Trichomonas vaginalis CMGC family protein kinase 0.0412 0.0326 0.129
Giardia lamblia Kinase, CMGC GSK 0.0863 0.1048 0.4447
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0302 0.0152 0.0485
Schistosoma mansoni protein kinase 0.0474 0.0427 0.0821
Brugia malayi Tyrosine-protein kinase PR2 0.0232 0.004 0.004
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0268 0.0097 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0237 0.0048 0.0034
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0535 0.0523 0.2096
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0268 0.0097 0.0097
Onchocerca volvulus 0.0253 0.0072 0.0138
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0232 0.004 0.0068
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.0099 0.0246
Echinococcus multilocularis protein tyrosine kinase 0.1074 0.1385 0.1433
Giardia lamblia Kinase 0.0232 0.004 0.013
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.027 0.0099 0.0259
Brugia malayi Protein kinase domain containing protein 0.0682 0.0759 0.0759
Echinococcus multilocularis protein kinase c epsilon type 0.1165 0.153 0.1583
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0561 0.0565 0.0565
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0381 0.0277 0.1028
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0943 0.1176 0.9404
Echinococcus granulosus casein kinase I alpha 0.0474 0.0427 0.0431
Loa Loa (eye worm) TK protein kinase 0.0792 0.0935 0.0935
Schistosoma mansoni protein kinase 0.0302 0.0152 0.0285
Echinococcus multilocularis hemicentin 1 0.0247 0.0063 0.006
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0386 0.0286 0.0288
Brugia malayi phosphoinositide-dependent protein kinase I 0.046 0.0404 0.0404
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0475 0.0427 0.1644
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0299 0.0146 0.0145
Entamoeba histolytica protein kinase, putative 0.0359 0.0242 0.0963
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Echinococcus granulosus tensin C1 domain containing phosphatase 0.021 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis STE family protein kinase 0.0919 0.1137 0.4591
Brugia malayi STE20-like kinase MST 0.1588 0.2206 0.2206
Echinococcus granulosus casein kinase I gamma 0.0355 0.0235 0.0236
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0255 0.0076 0.0076
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Toxoplasma gondii AGC kinase 0.1707 0.2397 1
Echinococcus multilocularis serine:threonine protein kinase 0.067 0.074 0.0763
Echinococcus granulosus TGF-beta receptor type-1 0.0223 0.0025 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0429 0.0355 0.0355
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0307 0.0159 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0912 0.1126 0.2182
Loa Loa (eye worm) AGC/PKA protein kinase 0.0535 0.0523 0.0523
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0356 0.0237 0.0855
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.0479 0.0434 0.0835
Trichomonas vaginalis CAMK family protein kinase 0.0749 0.0866 0.3486
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.004 0.0036
Brugia malayi Variant SH3 domain containing protein 0.0373 0.0264 0.0264
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0385 0.0283 0.0283
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Schistosoma mansoni serine/threonine kinase 0.069 0.0772 0.1492
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0099 0.0366
Echinococcus granulosus c src tyrosine kinase 0.0605 0.0635 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0988 0.1248 0.5045
Echinococcus granulosus dual specificity testis-specific protein kinase 0.1542 0.2132 0.2166
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0596 0.0622 0.0622
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0247 0.0063 0.0112
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Echinococcus granulosus hemicentin 1 0.0247 0.0063 0.0061
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1075 0.1387 0.1387
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0863 0.1048 0.203
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Giardia lamblia Kinase, CMGC CDK 0.0745 0.0859 0.3638
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Giardia lamblia Kinase, CMGC GSK 0.0863 0.1048 0.4447
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trypanosoma brucei cdc2-related kinase 3 0.0745 0.0859 0.3377
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Schistosoma mansoni serine/threonine kinase 0.0912 0.1126 0.2182
Trichomonas vaginalis AGC family protein kinase 0.092 0.1139 0.46
Trichomonas vaginalis CMGC family protein kinase 0.0475 0.0427 0.1702
Echinococcus granulosus tyrosine protein kinase Lyn 0.1103 0.1431 0.1453
Loa Loa (eye worm) hypothetical protein 0.0263 0.0089 0.0089
Brugia malayi Raf kinase 0.0232 0.004 0.004
Loa Loa (eye worm) TK protein kinase 0.1737 0.2444 0.2444
Schistosoma mansoni growth factor receptor-bound protein 0.0376 0.027 0.0517
Brugia malayi hypothetical protein 0.0232 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0356 0.0237 0.0855
Echinococcus granulosus serine:threonine protein kinase N2 0.106 0.1363 0.1384
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0608 0.1175
Echinococcus multilocularis dual specificity 0.027 0.0099 0.0098
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0302 0.0152 0.0152
Echinococcus granulosus nervana 2 0.0795 0.0939 0.0953
Schistosoma mansoni vam6/vps39 related 0.0237 0.0048 0.0084
Echinococcus granulosus cGMP dependent protein kinase 1 0.0265 0.0091 0.009
Schistosoma mansoni nephrin 0.0684 0.0762 0.1473
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis AGC family protein kinase 0.046 0.0404 0.1607
Loa Loa (eye worm) hypothetical protein 0.044 0.0371 0.0371
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0868 0.1055 0.107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0881 0.1077 0.1092
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.2483 0.3637 0.377
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1075 0.1387 0.1435
Loa Loa (eye worm) hypothetical protein 0.0558 0.056 0.056
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0234 0.0043 0.0154
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0232 0.004 0.0036
Echinococcus multilocularis myotubularin protein 13 0.0287 0.0128 0.0128
Echinococcus multilocularis unc 13 (munc13) 0.0253 0.0072 0.007
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Echinococcus multilocularis mitogen activated protein kinase 11 0.109 0.1411 0.146
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0232 0.004 0.004
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.2471 0.3618 0.3618
Brugia malayi casein kinase 1, delta 0.0474 0.0427 0.0427
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0682 0.0759 0.305
Giardia lamblia Kinase, CAMK CAMKL 0.0364 0.025 0.103
Echinococcus granulosus tyrosine protein kinase 0.0507 0.0478 0.0484
Trypanosoma cruzi cdc2-related kinase 3 0.0745 0.0859 0.3554
Echinococcus multilocularis Glutaredoxin protein 5 0.0795 0.0939 0.097
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Schistosoma mansoni serine/threonine protein kinase 0.106 0.1363 0.2644
Brugia malayi Protein kinase domain containing protein 0.0797 0.0943 0.0943
Brugia malayi Protein kinase domain containing protein 0.1401 0.1908 0.1908
Entamoeba histolytica protein kinase, putative 0.0912 0.1126 0.4556
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0218 0.0017 0.0014
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.004 0.0036
Loa Loa (eye worm) TK/EGFR protein kinase 0.3424 0.5142 0.5142
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0863 0.1048 0.4374
Entamoeba histolytica hypothetical protein 0.0435 0.0364 0.1458
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0755 0.0875 0.0903
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.0237 0.0452
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0907 0.1119 0.4683
Echinococcus multilocularis titin 0.0309 0.0163 0.0164
Schistosoma mansoni rap gtpase-activating protein 0.0237 0.0048 0.0084
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0474 0.0427 0.0427
Brugia malayi Protein kinase domain containing protein 0.0298 0.0145 0.0145
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.154 0.213 0.213
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis AGC family protein kinase 0.0988 0.1248 0.5045
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1875 0.2666 0.2763
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1588 0.2206 0.2206
Brugia malayi Protein kinase domain containing protein 0.0284 0.0123 0.0123
Entamoeba histolytica receptor protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus protein kinase 0.0232 0.004 0.0037
Schistosoma mansoni protein tyrosine kinase 0.0232 0.004 0.0068
Echinococcus multilocularis casein kinase i 0.0474 0.0427 0.0438
Entamoeba histolytica hypothetical protein 0.0234 0.0043 0.0154
Entamoeba histolytica casein kinase, putative 0.058 0.0596 0.2401
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1401 0.1908 0.1938
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0988 0.1248 0.5054
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.046 0.0404 0.0404
Schistosoma mansoni nck2/grb4 0.0373 0.0264 0.0504
Echinococcus granulosus fibroblast growth factor receptor 4 0.161 0.2242 0.2277
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0749 0.0866 0.3486
Echinococcus multilocularis dual specificity mitogen activated protein 0.0302 0.0152 0.0152
Echinococcus multilocularis tyrosine protein kinase HCK 0.0582 0.0599 0.0616
Entamoeba histolytica casein kinase 1, putative 0.0474 0.0427 0.1713
Echinococcus granulosus RNA directed DNA polymerase 0.0255 0.0076 0.0074
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0385 0.0283 0.2015
Echinococcus granulosus tyrosine protein kinase Src64B 0.0955 0.1194 0.1212
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0468 0.0417 0.0417
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Entamoeba histolytica diacylglycerol kinase, putative 0.0245 0.0059 0.0221
Brugia malayi Egg laying defective protein 4 0.0265 0.0091 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis calcium dependent protein kinase 0.0236 0.0046 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Giardia lamblia Kinase, PLK 0.1674 0.2344 1
Loa Loa (eye worm) hypothetical protein 0.0946 0.118 0.118
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis casein kinase I gamma 0.0355 0.0235 0.0239
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Echinococcus multilocularis 0.0263 0.0089 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0935 0.1163 0.4699
Brugia malayi Cam kinase protein 1 0.0385 0.0283 0.0283
Brugia malayi protein-tyrosine kinase 0.0792 0.0935 0.0935
Plasmodium falciparum protein kinase, putative 0.0381 0.0277 0.1961
Echinococcus granulosus mitogen activated protein kinase 3 0.0475 0.0427 0.0432
Echinococcus multilocularis twitchin 0.0275 0.0108 0.0107
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0745 0.0859 0.3554
Echinococcus granulosus serine:threonine kinase SAD 1 0.0356 0.0237 0.0238
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus neuroglian 0.065 0.0707 0.0716
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.161 0.2242 0.2322
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0912 0.1126 0.1164
Trichomonas vaginalis AGC family protein kinase 0.0988 0.1248 0.5045
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0268 0.0097 0.0097
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0535 0.0523 0.2096
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Entamoeba histolytica cell division protein kinase 2, putative 0.0745 0.0859 0.3471
Schistosoma mansoni tyrosine kinase 0.2002 0.2868 0.5574
Echinococcus granulosus Rac GTPase activating protein 1 0.0245 0.0059 0.0057
Entamoeba histolytica protein kinase, putative 0.0863 0.1048 0.4238
Echinococcus granulosus myotubularin protein 13 0.0287 0.0128 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Brugia malayi Protein kinase domain containing protein 0.0443 0.0376 0.0376
Echinococcus multilocularis roundabout 2 0.0804 0.0953 0.0985
Giardia lamblia Kinase, STE STE20 0.0302 0.0152 0.0608
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0475 0.0427 0.1682
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0326 0.0626
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Plasmodium vivax protein kinase Crk2 0.0745 0.0859 0.6777
Loa Loa (eye worm) raf kinase 0.0245 0.0059 0.0059
Onchocerca volvulus 0.0232 0.004 0.0072
Echinococcus multilocularis transfer RNA-Thr 0.0404 0.0315 0.0322
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0538
Schistosoma mansoni tyrosine protein kinase 0.0232 0.004 0.0068
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Echinococcus granulosus roundabout 2 0.0281 0.0118 0.0117
Trypanosoma cruzi casein kinase, putative 0.0474 0.0427 0.1678
Schistosoma mansoni serine/threonine protein kinase 0.0745 0.0859 0.1662
Toxoplasma gondii casein kinase I 0.0474 0.0427 0.1641
Brugia malayi Protein kinase domain containing protein 0.0412 0.0326 0.0326
Schistosoma mansoni cell adhesion molecule 0.0677 0.0751 0.1452
Loa Loa (eye worm) protein kinase domain-containing protein 0.0232 0.004 0.004
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Schistosoma mansoni septate junction protein 0.0247 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Brugia malayi RhoGAP domain containing protein 0.0455 0.0396 0.0396
Loa Loa (eye worm) TK/INSR protein kinase 0.2448 0.3582 0.3582
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis PAK box P21 Rho binding 0.0218 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Brugia malayi Temporarily assigned gene name protein 59 0.0829 0.0994 0.0994
Plasmodium falciparum protein serine/threonine kinase-1 0.0412 0.0326 0.237
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Echinococcus granulosus Vam6:Vps39 protein 0.0237 0.0048 0.0046
Entamoeba histolytica serine/threonine protein kinase, putative 0.1674 0.2344 0.9508
Schistosoma mansoni serine/threonine-protein kinase 0.0986 0.1245 0.2414
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0084 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus serine:threonine protein kinase 0.067 0.074 0.0749
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0523 0.0504 0.0972
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0212 0.0007 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Toxoplasma gondii AGC kinase 0.0535 0.0523 0.205
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0232 0.004 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0535 0.0523 0.1008
Echinococcus granulosus lachesin 0.0247 0.0063 0.0061
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0284 0.0123 0.0123
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0218 0.0017 0.0017
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1524 0.2105 0.2105
Giardia lamblia Kinase, CMGC DYRK 0.027 0.0099 0.0385
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0364 0.025 0.174
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0506 0.0477 0.049
Echinococcus granulosus tyrosine protein kinase otk 0.0247 0.0063 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.0863 0.1048 0.4228
Trichomonas vaginalis STE family protein kinase 0.0481 0.0437 0.174
Brugia malayi Ras association domain family 1 isoform A 0.0245 0.0059 0.0059
Trypanosoma brucei cdc2-related kinase 1 0.0745 0.0859 0.3377
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.1194 0.1212
Schistosoma mansoni adapter molecule crk 0.0373 0.0264 0.0504
Brugia malayi cell division control protein 2 homolog 0.0745 0.0859 0.0859
Brugia malayi STAT protein, DNA binding domain containing protein 0.021 0.0005 0.0005
Echinococcus granulosus aurora kinase A 0.0988 0.1248 0.1267
Giardia lamblia Kinase, AGC PKA 0.0943 0.1176 0.4998
Onchocerca volvulus 0.0946 0.118 0.2413
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.004 0.0036
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Plasmodium falciparum serine/threonine protein kinase, putative 0.0988 0.1248 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Echinococcus granulosus tyrosine protein kinase HCK 0.0582 0.0599 0.0606
Brugia malayi Protein kinase domain containing protein 0.1158 0.1519 0.1519
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0232 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Entamoeba histolytica hypothetical protein 0.0233 0.0041 0.0145
Loa Loa (eye worm) hypothetical protein 0.0759 0.0882 0.0882
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0605 0.0635 0.1227
Echinococcus multilocularis myosin iiia 0.0481 0.0437 0.0448
Echinococcus multilocularis mitogen activated protein kinase 14 0.109 0.1411 0.146
Echinococcus granulosus rho-associated protein kinase 1 0.2178 0.315 0.3202
Echinococcus granulosus dual specificity protein kinase clk2 0.0412 0.0326 0.0329
Entamoeba histolytica protein kinase domain containing protein 0.0988 0.1248 0.5054
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0232 0.004 0.0142
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0942 0.1174 0.1191
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0535 0.0523 0.3997
Echinococcus granulosus cyclin dependent kinase 7 0.0316 0.0174 0.0174
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis rho associated protein kinase 0.2178 0.315 0.3266
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0988 0.1248 0.1291
Echinococcus multilocularis expressed conserved protein 0.0265 0.0091 0.009
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) TK protein kinase 0.0232 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Trichomonas vaginalis CAMK family protein kinase 0.0242 0.0056 0.0189
Echinococcus multilocularis CDC7 cell division cycle 7 0.0213 0.0009 0.0005
Giardia lamblia Kinase, STE STE20 0.0506 0.0477 0.2001
Brugia malayi Protein kinase c protein 2 0.0656 0.0717 0.0717
Echinococcus multilocularis dual specificity 0.027 0.0099 0.0098
Brugia malayi casein kinase I 0.0474 0.0427 0.0427
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0281 0.0118 0.0219
Entamoeba histolytica protein kinase domain containing protein 0.027 0.0099 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0535 0.0523 0.2091
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0385 0.0283 0.0283
Brugia malayi Protein kinase domain containing protein 0.0912 0.1126 0.1126
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0108 0.0201
Onchocerca volvulus 0.1637 0.2285 0.4682
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0535 0.0523 0.2096
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis protein kinase c eta type 0.0245 0.0059 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Schistosoma mansoni serine/threonine protein kinase 0.111 0.1442 0.2798
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Schistosoma mansoni ephrin receptor 0.0267 0.0095 0.0175
Brugia malayi Protein kinase domain containing protein 0.2448 0.3582 0.3582
Brugia malayi P21-Rho-binding domain containing protein 0.0218 0.0017 0.0017
Echinococcus granulosus Immunoglobulin 0.0523 0.0504 0.051
Brugia malayi serine/threonine-protein kinase 6 0.0988 0.1248 0.1248
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0232 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.0299 0.0146 0.0274
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0988 0.1248 0.1267
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0538
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1165 0.153 0.153
Brugia malayi Temporarily assigned gene name protein 59 0.0237 0.0048 0.0048
Brugia malayi hypothetical protein 0.0443 0.0376 0.0376
Entamoeba histolytica diacylglycerol kinase, putative 0.0245 0.0059 0.0221
Echinococcus multilocularis rac serine:threonine kinase 0.0986 0.1245 0.1287
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus dual specificity 0.027 0.0099 0.0098
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0218 0.0017 0.0012
Schistosoma mansoni tyrosine kinase 0.1135 0.1483 0.2877
Entamoeba histolytica protein kinase, putative 0.175 0.2465 1
Echinococcus granulosus signal transduction protein lnk realted 0.021 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Echinococcus multilocularis insulin receptor 0.2448 0.3582 0.3713
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.0427 0.0821
Loa Loa (eye worm) AUR protein kinase 0.0988 0.1248 0.1248
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0496 0.0462 0.0462
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Entamoeba histolytica protein kinase, putative 0.0234 0.0043 0.0154
Echinococcus granulosus tyrosine protein kinase ABL1 0.1346 0.182 0.1848
Trichomonas vaginalis CMGC family protein kinase 0.0475 0.0427 0.1702
Echinococcus multilocularis neuroglian 0.065 0.0707 0.0729
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Leishmania major protein kinase, putative 0.0412 0.0326 0.1243
Brugia malayi SH2 domain containing protein 0.021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0443 0.0376 0.0376
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Onchocerca volvulus 0.0232 0.004 0.0072
Echinococcus granulosus Glutaredoxin protein 5 0.0795 0.0939 0.0953
Loa Loa (eye worm) hypothetical protein 0.0373 0.0264 0.0264
Echinococcus multilocularis death associated protein kinase 1 0.6237 0.9637 1
Leishmania major protein kinase, putative 0.0481 0.0437 0.1723
Brugia malayi protein unc-22 0.0309 0.0163 0.0163
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0769 0.0898 0.0898
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.1194 0.1235
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) TK/ACK protein kinase 0.0232 0.004 0.004
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0232 0.004 0.0036
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0298 0.0145 0.0145
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0232 0.004 0.0072
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.2053 0.295 0.295
Echinococcus multilocularis calcium activated potassium channel 0.0588 0.0608 0.0626
Toxoplasma gondii aurora kinase 0.0988 0.1248 0.5128
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0386 0.0285 0.0287
Plasmodium falciparum calcium-dependent protein kinase 4 0.0385 0.0283 0.2015
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.109 0.1411 0.1411
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0342 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0525 0.0507 0.0507
Echinococcus granulosus protein kinase c epsilon type 0.1165 0.153 0.1553
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1753 0.2471 0.256
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0381 0.0277 0.1028
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0265 0.0091 0.009
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0955 0.1194 0.1235
Onchocerca volvulus 0.0232 0.004 0.0072
Schistosoma mansoni unc-13 (munc13) 0.0253 0.0072 0.0131
Entamoeba histolytica serine/threonine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0682 0.0759 0.0759
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0385 0.0283 0.0289
Loa Loa (eye worm) RGC/RGC protein kinase 0.0232 0.004 0.004
Echinococcus granulosus epidermal growth factor receptor 0.3424 0.5142 0.5228
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0912 0.1126 0.1143
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0745 0.0859 0.3475
Echinococcus granulosus tyrosine protein kinase Blk 0.0792 0.0935 0.0948
Echinococcus multilocularis protein kinase shaggy 0.0863 0.1048 0.1083
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus activated cdc42 kinase 1 0.0404 0.0315 0.0317
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0474 0.0427 0.0427
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica PH domain containing protein kinase, putative 0.0577 0.0591 0.2384
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Leishmania major protein kinase, putative 0.0412 0.0326 0.1243
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0412 0.0326 0.1243
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0523 0.0504 0.0972
Echinococcus multilocularis Diacylglycerol kinase theta 0.0245 0.0059 0.0057
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0215 0.0012 0.0008
Echinococcus multilocularis protein KINase family member (kin 25) 0.0299 0.0146 0.0146
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0475 0.0427 0.0427
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0795 0.0939 0.0953
Echinococcus multilocularis mitogen activated protein kinase 0.0475 0.0427 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.0988 0.1248 0.2421
Loa Loa (eye worm) hypothetical protein 0.0765 0.0891 0.0891
Loa Loa (eye worm) SH2 domain-containing protein 0.021 0.0005 0.0005
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0237 0.0048 0.0045
Echinococcus granulosus SH2 motif 0.021 0.0005 0.0002
Echinococcus granulosus contactin 0.0281 0.0118 0.0117
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) serine/threonine protein kinase 0.0232 0.004 0.004
Echinococcus granulosus raf serine:threonine protein kinase 0.0477 0.0431 0.0435
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Schistosoma mansoni tyrosine kinase 0.1595 0.2218 0.4308
Onchocerca volvulus 0.2898 0.4301 0.8822
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0316 0.0174 0.0174
Trypanosoma brucei protein kinase, putative 0.0483 0.044 0.1652
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0232 0.004 0.0068
Schistosoma mansoni ste20-related kinase 0.1255 0.1675 0.3251
Loa Loa (eye worm) hypothetical protein 0.1281 0.1716 0.1716
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) protein kinase domain-containing protein 0.0355 0.0235 0.0235
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.067 0.074 0.2973
Echinococcus granulosus calcium activated potassium channel 0.0588 0.0608 0.0616
Echinococcus multilocularis natriuretic peptide receptor 1 0.0232 0.004 0.0036
Plasmodium falciparum calcium-dependent protein kinase 5 0.0385 0.0283 0.2015
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0236 0.0046 0.0043
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0232 0.004 0.004
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0385 0.0283 0.0285
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0113 0.5
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0232 0.004 0.004
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0342 0.0216 0.0219
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0955 0.1194 0.1235
Schistosoma mansoni hypothetical protein 0.0218 0.0017 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0119 0.0221
Echinococcus granulosus suppressor of cytokine signaling 6 0.021 0.0005 0.0002
Brugia malayi serine/threonine-protein kinase plk-2 0.1674 0.2344 0.2344
Brugia malayi cytokine inducible SH2-containing protein 5 0.021 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Plasmodium falciparum calcium-dependent protein kinase 3 0.0385 0.0283 0.2015
Brugia malayi Protein kinase domain containing protein 0.0355 0.0235 0.0235
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0385 0.0283 0.0285
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Echinococcus granulosus tyrosine kinase 0.0443 0.0376 0.038
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0608 0.1175
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0232 0.004 0.0068
Plasmodium vivax calcium-dependent protein kinase, putative 0.0385 0.0283 0.2015
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Onchocerca volvulus 0.203 0.2913 0.5972
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.004 0.0036
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0529
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.046 0.0404 0.0414
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi Variant SH3 domain containing protein 0.0261 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Leishmania major protein kinase, putative 0.0988 0.1248 0.5245
Schistosoma mansoni serine/threonine protein kinase 0.0942 0.1174 0.2276
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0943 0.1176 0.1216
Echinococcus multilocularis cyclin dependent kinase 0.0745 0.0859 0.0887
Trichomonas vaginalis CK1 family protein kinase 0.0474 0.0427 0.1698
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.2234 0.324 0.3293
Loa Loa (eye worm) hypothetical protein 0.0558 0.056 0.056
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0237 0.0048 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0356 0.0237 0.0237
Echinococcus granulosus ephrin type A receptor 4 A 0.0644 0.0698 0.0707
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Schistosoma mansoni tyrosine kinase 0.0605 0.0635 0.1227
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Entamoeba histolytica protein kinase, putative 0.0392 0.0295 0.1178
Schistosoma mansoni ephrin receptor 0.0644 0.0698 0.1349
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0232 0.004 0.004
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0385 0.0283 0.0283
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0807 0.0958 0.0958
Giardia lamblia Kinase, AGC AKT 0.0776 0.0909 0.3854
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0288 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0557 0.0559 0.0559
Giardia lamblia Kinase, CMGC CLK 0.0412 0.0326 0.1357
Loa Loa (eye worm) hypothetical protein 0.1948 0.2782 0.2782
Brugia malayi Hr1 repeat family protein 0.106 0.1363 0.1363
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0535 0.0523 0.0529
Echinococcus granulosus cGMP dependent protein kinase 0.0265 0.0091 0.009
Schistosoma mansoni serine/threonine protein kinase 0.1524 0.2105 0.4088
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0232 0.004 0.0072
Schistosoma mansoni protein kinase 0.1542 0.2132 0.4141
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0863 0.1048 0.1083
Echinococcus multilocularis NCK adaptor protein 0.0376 0.027 0.0276
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0282 0.0119 0.0119
Echinococcus multilocularis dual specificity 0.0907 0.1119 0.1157
Entamoeba histolytica protein kinase, putative 0.0988 0.1248 0.5054
Onchocerca volvulus 0.0232 0.004 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0949 0.1185 0.1185
Echinococcus multilocularis cyclin dependent kinase 1 0.0745 0.0859 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Brugia malayi hypothetical protein 0.021 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) AGC/PKN protein kinase 0.106 0.1363 0.1363
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0288 0.0128 0.0385
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0907 0.1119 0.4683
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0282 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.079 0.0931 0.0961
Trichomonas vaginalis STE family protein kinase 0.0506 0.0477 0.1903
Brugia malayi Immunoglobulin I-set domain containing protein 0.3773 0.5699 0.5699
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1674 0.2344 0.2382
Entamoeba histolytica protein kinase, putative 0.0506 0.0477 0.1917
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.1674 0.2344 0.9507
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0373 0.0264 0.0264
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0373 0.0264 0.0504
Echinococcus granulosus cyclin dependent kinase 5 0.0745 0.0859 0.0871
Schistosoma mansoni serine/threonine protein kinase 0.0535 0.0523 0.1008
Brugia malayi Immunoglobulin I-set domain containing protein 0.1737 0.2444 0.2444
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Brugia malayi protein kinase C3,putative 0.0926 0.1148 0.1148
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0455 0.0396 0.0406
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0955 0.1194 0.1235
Loa Loa (eye worm) SH2 domain-containing protein 0.021 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0443 0.0376 0.0376
Loa Loa (eye worm) AUR protein kinase 0.0988 0.1248 0.1248
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1419 0.1937 0.2006
Schistosoma mansoni protein kinase 0.0755 0.0875 0.1694
Trypanosoma brucei protein kinase, putative 0.0863 0.1048 0.4156
Entamoeba histolytica p21-activated kinase 0.0549 0.0545 0.2196
Echinococcus multilocularis RNA directed DNA polymerase 0.0255 0.0076 0.0074
Echinococcus granulosus tyrosine protein kinase Fps85D 0.079 0.0931 0.0944
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0907 0.1119 0.4683
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0245 0.0059 0.0059
Echinococcus granulosus protein kinase shaggy 0.0863 0.1048 0.1063
Trichomonas vaginalis AGC family protein kinase 0.046 0.0404 0.1607
Echinococcus multilocularis integrin linked protein kinase 0.0232 0.004 0.0036
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0755 0.0875 0.0887
Loa Loa (eye worm) STAT protein 0.021 0.0005 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.1674 0.2344 1
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0437 0.0367 0.0371
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0288 0.0128 0.0128
Echinococcus multilocularis tyrosine protein kinase Abl 0.095 0.1187 0.1227
Echinococcus granulosus tyrosine protein kinase pr2 0.0232 0.004 0.0037
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0211 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus serine/threonine protein kinase 0.0986 0.1245 0.1263
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0385 0.0283 0.0285
Echinococcus multilocularis Rac GTPase activating protein 1 0.0245 0.0059 0.0057
Echinococcus multilocularis protein kinase 0.0232 0.004 0.0036
Echinococcus granulosus titin 0.0309 0.0163 0.0163
Schistosoma mansoni diacylglycerol kinase theta 0.0245 0.0059 0.0106
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0774 0.0906 0.0906
Echinococcus granulosus receptor type guanylyl cyclase 0.0232 0.004 0.0037
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0283 0.0121 0.0121
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.111 0.1442 0.1492
Brugia malayi cyclin-dependent kinase 7 homolog 0.0324 0.0187 0.0187
Loa Loa (eye worm) RasGEF domain-containing protein 0.0245 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0437 0.0367 0.0367
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.046 0.0404 0.0408
Schistosoma mansoni tyrosine kinase 0.2234 0.324 0.6297
Echinococcus granulosus serine:threonine protein kinase 3 0.1588 0.2206 0.2241
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0232 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0287 0.0128 0.0128
Schistosoma mansoni cell adhesion molecule 0.0281 0.0118 0.0219
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0232 0.004 0.0037
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0265 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Brugia malayi putative serine/threonine kinase SADA gamma 0.0356 0.0237 0.0237
Echinococcus granulosus mitogen activated protein kinase 14 0.109 0.1411 0.1433
Schistosoma mansoni hypothetical protein 0.044 0.0371 0.0713
Onchocerca volvulus 0.0232 0.004 0.0072
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1075 0.1387 0.1408
Entamoeba histolytica protein kinase domain containing protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0228 0.0034 0.0034
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0535 0.0523 0.1992
Entamoeba histolytica PH domain containing protein kinase, putative 0.0577 0.0591 0.2384
Echinococcus granulosus mitogen activated protein kinase 0.0475 0.0427 0.0432
Echinococcus multilocularis nervana 2 0.0795 0.0939 0.097
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0965 0.1211 0.1211
Onchocerca volvulus 0.0443 0.0376 0.0762
Trichomonas vaginalis TK family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0232 0.004 0.0124
Loa Loa (eye worm) hypothetical protein 0.0274 0.0107 0.0107
Brugia malayi Protein kinase domain containing protein 0.1006 0.1277 0.1277
Trypanosoma cruzi Protein kinase B 0.0986 0.1245 0.523
Brugia malayi diacylglycerol kinase 0.0245 0.0059 0.0059
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0863 0.1048 0.4374
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Schistosoma mansoni protein kinase 0.0232 0.004 0.0068
Loa Loa (eye worm) hypothetical protein 0.0404 0.0315 0.0315
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0499 0.0467 0.0467
Echinococcus granulosus retinal guanylyl cyclase 2 0.0232 0.004 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.0237 0.0452
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0253 0.0072 0.007
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Giardia lamblia Kinase, NEK 0.0919 0.1137 0.4829
Echinococcus multilocularis serine:threonine protein kinase N2 0.0912 0.1126 0.1164
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Brugia malayi SRC-1 0.0955 0.1194 0.1194
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0863 0.1048 0.1048
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0643 0.0696 0.0705
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.0427 0.0822
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0099 0.0184
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Schistosoma mansoni protein kinase C mu 0.0245 0.0059 0.0106
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0955 0.1194 0.1235
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0302 0.0152 0.0485
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0412 0.0326 0.1243
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Echinococcus multilocularis hypothetical protein 0.044 0.0371 0.038
Giardia lamblia Kinase, NEK 0.0232 0.004 0.013
Schistosoma mansoni tyrosine kinase 0.0955 0.1194 0.2315
Schistosoma mansoni titin 0.0309 0.0163 0.0308
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0792 0.0935 0.0966
Echinococcus multilocularis PAK box P21 Rho binding 0.0366 0.0254 0.0258
Giardia lamblia Kinase, CMGC CDK 0.0745 0.0859 0.3638
Trypanosoma brucei polo-like protein kinase 0.1674 0.2344 0.9501
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Onchocerca volvulus 0.0443 0.0376 0.0762
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0163 0.0308
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0281 0.0118 0.0117
Schistosoma mansoni tyrosine kinase 0.0232 0.004 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Echinococcus multilocularis tyrosine kinase 0.0443 0.0376 0.0385
Trypanosoma brucei protein kinase, putative 0.0381 0.0277 0.0977
Echinococcus granulosus tyrosine protein kinase Srms 0.0909 0.1122 0.1138
Trypanosoma cruzi aurora B kinase, putative 0.0988 0.1248 0.5245
Echinococcus granulosus casein kinase ii subunit alpha 0.058 0.0596 0.0603
Entamoeba histolytica ankyrin repeat protein 0.0232 0.004 0.0142
Loa Loa (eye worm) hypothetical protein 0.0528 0.0512 0.0512
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus dual specificity 0.027 0.0099 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0253 0.0072 0.0071
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0386 0.0286 0.0292
Loa Loa (eye worm) hypothetical protein 0.0245 0.0059 0.0059
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Giardia lamblia Kinase, CMGC MAPK 0.0475 0.0427 0.179
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0063 0.0063
Entamoeba histolytica serine/threonine protein kinase, putative 0.0356 0.0237 0.0943
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0795 0.0939 0.097
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.021 0.0005 0.0005
Echinococcus multilocularis activin receptor type 0.0761 0.0885 0.0913
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0342 0.0216 0.0217
Loa Loa (eye worm) AGC/PKA protein kinase 0.0535 0.0523 0.0523
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0247 0.0063 0.0063
Loa Loa (eye worm) TK/RYK protein kinase 0.0232 0.004 0.004
Brugia malayi Serine/threonine-protein kinase SULU 0.0561 0.0565 0.0565
Echinococcus granulosus defective proboscis extension response 0.0523 0.0504 0.051
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0535 0.0523 0.2096
Onchocerca volvulus 0.0237 0.0048 0.0088
Echinococcus multilocularis nervana 2 0.0795 0.0939 0.097
Loa Loa (eye worm) hypothetical protein 0.021 0.0005 0.0005
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.021 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Echinococcus multilocularis tyrosine protein kinase Blk 0.0792 0.0935 0.0966
Echinococcus multilocularis kinase suppressor of Ras 1 0.0232 0.004 0.0036
Brugia malayi serine/threonine protein kinase 6 0.0988 0.1248 0.1248
Loa Loa (eye worm) hypothetical protein 0.0643 0.0696 0.0696
Schistosoma mansoni tyrosine kinase 0.1074 0.1385 0.2686
Echinococcus granulosus N chimaerin 0.0455 0.0396 0.04
Echinococcus multilocularis receptor type guanylyl cyclase 0.0232 0.004 0.0036
Echinococcus multilocularis heat shock protein 70 0.0232 0.004 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0942 0.1174 0.2276
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0348 0.0225 0.0225
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0236 0.0046 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0232 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0359 0.0242 0.0246
Toxoplasma gondii histone kinase SNF1, putative 0.0356 0.0237 0.0836
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0676 0.0749 0.0773
Loa Loa (eye worm) hypothetical protein 0.0557 0.0559 0.0559
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Entamoeba histolytica protein kinase, putative 0.0907 0.1119 0.4528
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0232 0.004 0.0037
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0523 0.0504 0.0518
Trichomonas vaginalis STE family protein kinase 0.0506 0.0477 0.1903
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.0128 0.024
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1524 0.2105 0.2105
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.024 0.0938
Loa Loa (eye worm) hypothetical protein 0.0237 0.0048 0.0048
Entamoeba histolytica hypothetical protein 0.0232 0.004 0.0142
Echinococcus multilocularis protein kinase 0.0232 0.004 0.0036
Schistosoma mansoni protein kinase C mu 0.1051 0.1349 0.2615
Schistosoma mansoni tyrosine kinase 0.2448 0.3582 0.6962
Loa Loa (eye worm) hypothetical protein 0.0232 0.004 0.004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.1194 0.1212
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.0123 0.023
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus cyclin dependent kinase 0.0745 0.0859 0.0871
Giardia lamblia Kinase, NEK 0.0919 0.1137 0.4829
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Echinococcus granulosus protein kinase c eta type 0.0245 0.0059 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0392 0.0295 0.0301
Trichomonas vaginalis CK1 family protein kinase 0.0474 0.0427 0.1698
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0215 0.0012 0.0008
Echinococcus multilocularis casein kinase I alpha 0.0474 0.0427 0.0438
Echinococcus granulosus natriuretic peptide receptor 1 0.0232 0.004 0.0037
Brugia malayi Pleckstrin Homology Domain 0.0287 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.004 0.0124
Entamoeba histolytica protein kinase, putative 0.0232 0.004 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.058 0.0596 0.2387
Echinococcus multilocularis tyrosine protein kinase csk 0.0232 0.004 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.2471 0.3618 0.7033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0272 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0299 0.0146 0.0146
Echinococcus granulosus dual specificity 0.0907 0.1119 0.1135
Entamoeba histolytica protein kinase, putative 0.0409 0.0322 0.129
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0676 0.0749 0.0759
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.6464 1 1
Entamoeba histolytica protein kinase, putative 0.0907 0.1119 0.4528
Giardia lamblia Aurora kinase 0.0988 0.1248 0.5307
Leishmania major protein kinase A catalytic subunit isoform 2 0.0535 0.0523 0.2096
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0455 0.0396 0.0761
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0232 0.004 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0943 0.1176 0.4932
Brugia malayi Casein kinase II, alpha chain 0.058 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0237 0.0048 0.0048
Onchocerca volvulus 0.0213 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0356 0.0237 0.0926
Schistosoma mansoni protein kinase 0.0218 0.0017 0.0023
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0212 0.0007 0.0007
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0247 0.0063 0.006
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0955 0.1194 0.1235
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.109 0.1411 0.5951
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Plasmodium falciparum cGMP-dependent protein kinase 0.0265 0.0091 0.0427
Echinococcus granulosus serine:threonine protein kinase MARK2 0.111 0.1442 0.1464
Plasmodium falciparum protein kinase 5 0.0745 0.0859 0.6777
Entamoeba histolytica protein kinase , putative 0.0988 0.1248 0.5054
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.0215 0.0012 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.004 0.0124
Trichomonas vaginalis AGC family protein kinase 0.175 0.2465 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0912 0.1126 0.1143
Brugia malayi bone morphogenetic protein type 1 receptor 0.0307 0.0159 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0118 0.0118
Echinococcus granulosus growth factor receptor bound protein 2 0.0376 0.027 0.0272
Loa Loa (eye worm) hypothetical protein 0.0247 0.0063 0.0063
Loa Loa (eye worm) TK/ABL protein kinase 0.1346 0.182 0.182
Entamoeba histolytica tyrosine kinase, putative 0.0232 0.004 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0535 0.0523 0.1008
Loa Loa (eye worm) TK/FER protein kinase 0.0232 0.004 0.004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0281 0.0118 0.0118
Entamoeba histolytica protein kinase, putative 0.027 0.0099 0.0384
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3773 0.5699 0.5699
Trichomonas vaginalis TKL family protein kinase 0.0232 0.004 0.0124
Onchocerca volvulus 0.0325 0.0189 0.0378
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0745 0.0859 0.0871
Echinococcus granulosus insulin receptor 0.2448 0.3582 0.364
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0232 0.004 0.0142
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1524 0.2105 0.218
Brugia malayi Protein kinase domain containing protein 0.0232 0.004 0.004
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0232 0.004 0.004
Schistosoma mansoni protein kinase 0.058 0.0596 0.115
Schistosoma mansoni tyrosine kinase 0.0605 0.0635 0.1227
Schistosoma mansoni hypothetical protein 0.0245 0.0059 0.0106
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0163 0.0163
Echinococcus multilocularis 0.0348 0.0225 0.0228

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 20.7491 uM PUBCHEM_BIOASSAY: Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID504465] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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