Detailed information for compound 1534675

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 365.34 | Formula: C20H26Cl2N2
  • H donors: 0 H acceptors: 0 LogP: 4.85 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClC(c1ccccc1)CCN1CCN(CC1)Cc1ccccc1.Cl
  • InChi: 1S/C20H25ClN2.ClH/c21-20(19-9-5-2-6-10-19)11-12-22-13-15-23(16-14-22)17-18-7-3-1-4-8-18;/h1-10,20H,11-17H2;1H
  • InChiKey: JTZXLFKYDFGODK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.0033 0.0069
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0479 0.126
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0259 0.0253
Schistosoma mansoni hypothetical protein 0.0164 0.081 0.0804
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0011 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0028 0.0021
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0066 0.0159
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0066 0.0159
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0479 0.0472
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0046 0.0105
Mycobacterium ulcerans glutaminase 0.1083 0.5989 0.5984
Brugia malayi ImpB/MucB/SamB family protein 0.0171 0.0847 0.0841
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0099 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0124 0.0117
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Trichomonas vaginalis mercuric reductase, putative 0.0098 0.0439 0.0733
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0091 0.0225
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0034 0.0056
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.0033 0.0026
Echinococcus granulosus bloom syndrome protein 0.0111 0.0512 0.0505
Brugia malayi Flap endonuclease-1 0.0025 0.0028 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0184 0.0473
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0115 0.0363
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0109 0.0096
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0612 0.1617
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0124 0.0117
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0098 0.0439 0.1437
Leishmania major phosphoglycerate kinase C, glycosomal 0.0165 0.0814 0.2156
Onchocerca volvulus 0.0184 0.0923 0.3923
Brugia malayi beta-lactamase family protein 0.0039 0.0103 0.0096
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0171 0.0847 0.0841
Onchocerca volvulus 0.0049 0.016 0.0563
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0099 0.0298
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0122 0.0115
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.005 0.0116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Mycobacterium ulcerans hypothetical protein 0.0101 0.0452 0.044
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0098 0.0439 0.1437
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0075
Brugia malayi Pre-SET motif family protein 0.0203 0.1032 0.1026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0701 0.0695
Loa Loa (eye worm) dihydrofolate reductase 0.1795 1 1
Loa Loa (eye worm) D-ets-2 protein 0.0042 0.0124 0.0122
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0279 0.1457 0.1446
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0479 0.0477
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0124 0.0117
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0337 0.0331
Brugia malayi Glycosyl hydrolases family 31 protein 0.0318 0.1679 0.1674
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Loa Loa (eye worm) ets-domain-containing protein 0.0042 0.0124 0.0122
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0124 0.0117
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0306 0.03
Chlamydia trachomatis dihydrofolate reductase 0.1795 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0103 0.009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0196 0.0992 0.263
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0666 0.1759
Leishmania major hypothetical protein, conserved 0.0039 0.0103 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0284 0.0739
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0212 0.0549
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0337 0.0336
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0109 0.0102
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0067 0.0194
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0026 0.0033 0.0069
Schistosoma mansoni hypothetical protein 0.008 0.0337 0.0331
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0612 0.0606
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0689 0.0683
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0026 0.0033 0.0026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0124 0.0117
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0026 0.0033 0.0019
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.0077 0.007
Leishmania major phosphoglycerate kinase B, cytosolic 0.0165 0.0814 0.2156
Mycobacterium tuberculosis Probable reductase 0.0647 0.3531 0.3522
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.0077 0.007
Brugia malayi serine/threonine-protein kinase plk-2 0.0281 0.1469 0.1463
Echinococcus granulosus ETS domain containing protein Elk 1 0.0042 0.0124 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0103 0.0172
Giardia lamblia Sgs1 DNA helicase, putative 0.0057 0.0207 0.0649
Trichomonas vaginalis rotamase, putative 0.0033 0.0071 0.0119
Brugia malayi jmjC domain containing protein 0.0247 0.1277 0.1271
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0033 0.0069
Echinococcus granulosus intestinal type alkaline phosphatase 0.0157 0.0773 0.0767
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0146 0.0139
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0168 0.0431
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0034 0.0056
Schistosoma mansoni apoptosis regulator bax 0.008 0.0337 0.0331
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0026 0.0033 0.0026
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.0033 0.0026
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0026 0.0033 0.0069
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0124 0.0402
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0124 0.0117
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0048 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.016 0.0147
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0026 0.0033 0.0019
Plasmodium vivax importin-beta 2, putative 0.0029 0.005 0.0116
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0019 0.0032
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0157 0.0773 0.0767
Echinococcus multilocularis ETS transcription factor Elf 5 0.0042 0.0124 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0124 0.0117
Trypanosoma brucei unspecified product 0.0118 0.0549 0.1447
Trypanosoma brucei DNA damage repair protein, putative 0.0053 0.0184 0.0473
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0124 0.0117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0196 0.0992 0.263
Echinococcus multilocularis heat shock protein 90 0.0032 0.0066 0.0059
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0017 0.001
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0066 0.0159
Mycobacterium ulcerans NADH dehydrogenase 0.0026 0.0033 0.0019
Treponema pallidum NADH oxidase 0.0098 0.0439 0.1379
Schistosoma mansoni ets 0.0042 0.0124 0.0117
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0026 0.0033 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0479 0.0799
Brugia malayi Dihydrofolate reductase 0.1795 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0166 0.0165
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0146 0.0139
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0689 0.0683
Schistosoma mansoni chromobox protein 0.0067 0.0266 0.0259
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0124 0.0402
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0177 0.0883 0.2339
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0067 0.016
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0046 0.0127
Giardia lamblia NADH oxidase lateral transfer candidate 0.0098 0.0439 0.1397
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0184 0.0473
Mycobacterium ulcerans ferredoxin reductase 0.0026 0.0033 0.0019
Brugia malayi nuclear receptor RXR 0.0022 0.0011 0.0005
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0067 0.016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0124 0.0117
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0041 0.0116 0.0109
Loa Loa (eye worm) glutaminase 2 0.1083 0.5989 0.5988
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0066 0.0159
Brugia malayi glutamate synthase 0.0026 0.0033 0.0026
Brugia malayi MH2 domain containing protein 0.0236 0.1218 0.1212
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0124 0.0117
Mycobacterium tuberculosis Conserved protein 0.0039 0.0103 0.009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0701 0.0695
Giardia lamblia PHD finger protein 15 0.0058 0.0212 0.0665
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0098 0.0439 0.1155
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0171 0.0847 0.0841
Brugia malayi Pre-SET motif family protein 0.0031 0.0059 0.0053
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.016 0.0147
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0103 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Trypanosoma brucei DNA polymerase kappa, putative 0.0177 0.0883 0.2339
Giardia lamblia Grp94/Hsp90 0.0025 0.0029 0.0073
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0013 0.0018
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0034 0.0056
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0146 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0124 0.0117
Schistosoma mansoni hypothetical protein 0.0082 0.0347 0.034
Echinococcus multilocularis lysosomal alpha glucosidase 0.0318 0.1679 0.1674
Brugia malayi nuclear receptor NHR-88 0.0042 0.0124 0.0117
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0109 0.0273
Mycobacterium leprae Probable lipase LipE 0.0039 0.0103 0.009
Leishmania major DNA polymerase eta, putative 0.0078 0.0323 0.0844
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.0339 0.0333
Mycobacterium ulcerans hypothetical protein 0.0049 0.016 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Schistosoma mansoni ets-related 0.0884 0.4867 0.4864
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0098 0.0439 0.1155
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0036 0.0061
Schistosoma mansoni alkaline phosphatase 0.0157 0.0773 0.0767
Brugia malayi Bloom's syndrome protein homolog 0.0111 0.0512 0.0505
Treponema pallidum heat shock protein 90 0.0025 0.0029 0.0052
Echinococcus granulosus microtubule associated protein 2 0.1348 0.7483 0.7481
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0066 0.0159
Echinococcus granulosus ETS transcription factor Elf 1 0.0042 0.0124 0.0117
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0098 0.0439 0.0433
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Echinococcus granulosus endoplasmin 0.0025 0.0029 0.0023
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0028 0.0056
Echinococcus granulosus chromobox protein 1 0.0067 0.0266 0.0259
Brugia malayi ecdysteroid receptor 0.0042 0.0124 0.0117
Plasmodium falciparum glutathione reductase 0.0098 0.0439 0.1155
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.005 0.0116
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.027 0.0704
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0098 0.0439 0.0427
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0032
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0103 0.0172
Schistosoma mansoni hypothetical protein 0.0042 0.0124 0.0117
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.0077 0.007
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0686 0.3753 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0124 0.0117
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0103 0.0096
Brugia malayi jmjC domain containing protein 0.0034 0.0077 0.007
Entamoeba histolytica phosphoglycerate kinase, putative 0.0165 0.0814 0.2608
Trichomonas vaginalis maltase-glucoamylase, putative 0.0071 0.0284 0.0473
Echinococcus granulosus lysine specific demethylase 5A 0.0134 0.0641 0.0635
Plasmodium falciparum flap endonuclease 1 0.0025 0.0028 0.0056
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0103 0.009
Brugia malayi Bromodomain containing protein 0.0041 0.0114 0.0107
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0013 0.0018
Echinococcus granulosus neutral alpha glucosidase AB 0.0071 0.0284 0.0277
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0479 0.0799
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0026 0.0033 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0082 0.0075
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0479 0.0466
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.0033 0.0026
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0612 0.1617
Loa Loa (eye worm) hypothetical protein 0.0057 0.0207 0.0206
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0109 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0124 0.0122
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0026 0.0033 0.0069
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0011 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.0077 0.007
Mycobacterium ulcerans glutamate synthase subunit beta 0.0026 0.0033 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0131 0.0219
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0452 0.044
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0028 0.0056
Trypanosoma cruzi DNA damage repair protein, putative 0.0053 0.0184 0.0473
Schistosoma mansoni hypothetical protein 0.0058 0.0212 0.0206
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0026 0.0033 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0042 0.0124 0.0122
Plasmodium vivax ferrodoxin reductase, putative 0.0026 0.0033 0.0069
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0666 0.1759
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0077 0.0187
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0124 0.0117
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0071 0.0285 0.0742
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0026 0.0033 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0479 0.0472
Schistosoma mansoni cpg binding protein 0.0097 0.043 0.0424
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0011 0.0005
Schistosoma mansoni elf1 0.0042 0.0124 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0124 0.0117
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0337 0.0331
Mycobacterium ulcerans lipase LipD 0.0039 0.0103 0.009
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0109 0.031
Trichomonas vaginalis apoptosis inducing factor, putative 0.0026 0.0033 0.0054
Schistosoma mansoni ap endonuclease 0.004 0.0109 0.0102
Mycobacterium tuberculosis Conserved protein 0.0039 0.0103 0.009
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.0033 0.0054
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0146 0.0145
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0026 0.0033 0.0019
Echinococcus multilocularis lysine specific demethylase 5A 0.0127 0.0602 0.0596
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0124 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0026 0.0033 0.0069
Schistosoma mansoni DNA polymerase eta 0.0195 0.0986 0.098
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0075
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0165 0.0814 0.2156
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0124 0.0117
Echinococcus multilocularis ETS transcription factor Elf 1 0.0042 0.0124 0.0117
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0029 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0098 0.0439 0.1155
Echinococcus multilocularis heat shock protein 90 0.0025 0.0029 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0124 0.0117
Echinococcus multilocularis glutamate synthase 0.0026 0.0033 0.0026
Giardia lamblia Fructose-bisphosphate aldolase 0.0571 0.3103 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0719 0.3937 0.3929
Plasmodium vivax thioredoxin reductase, putative 0.0284 0.1483 0.3942
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Echinococcus multilocularis protein C ets 2 0.0042 0.0124 0.0117
Schistosoma mansoni rotamase 0.0033 0.0071 0.0064
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0026 0.0033 0.0065
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0026 0.0033 0.0054
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0026 0.0033 0.0026
Echinococcus granulosus peregrin 0.0064 0.0245 0.0238
Brugia malayi phosphofructokinase 0.0105 0.0479 0.0472
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0124 0.0117
Brugia malayi mbt repeat family protein 0.0046 0.0146 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0011 0.0005
Leishmania major hypothetical protein, conserved 0.0034 0.0077 0.0187
Echinococcus multilocularis cpg binding protein 0.0097 0.043 0.0424
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0099 0.0298
Brugia malayi CXXC zinc finger family protein 0.009 0.0391 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0109 0.0182
Onchocerca volvulus 0.003 0.0053 0.0089
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0059 0.022 0.057
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0479 0.0799
Giardia lamblia DNA damage repair protein 0.0053 0.0184 0.0573
Trichomonas vaginalis DNA helicase recq, putative 0.0111 0.0512 0.0854
Brugia malayi beta-lactamase family protein 0.0039 0.0103 0.0096
Schistosoma mansoni endoplasmin 0.0032 0.0066 0.0059
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0072 0.0292 0.0286
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0109 0.0102
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0212 0.0549
Mycobacterium ulcerans dehydrogenase 0.0026 0.0033 0.0019
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1534 0.4076
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0754 0.0741
Entamoeba histolytica thioredoxin reductase, putative 0.0026 0.0033 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0117 0.0296
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0091 0.0078
Trypanosoma cruzi trypanothione reductase, putative 0.0284 0.1483 0.3942
Echinococcus multilocularis microtubule associated protein 2 0.1348 0.7483 0.7481
Echinococcus granulosus geminin 0.0164 0.081 0.0804
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0029 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0077 0.0075
Echinococcus multilocularis chromobox protein 1 0.0067 0.0266 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.0585 0.1543
Echinococcus multilocularis endoplasmin 0.0025 0.0029 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.1469 0.1463
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0182 0.0175
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.1218 0.1217
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0337 0.0331
Brugia malayi glutaminase DH11.1 0.1083 0.5989 0.5986
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0099 0.0291
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0026 0.0033 0.0031
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0067 0.016
Brugia malayi jmjC domain containing protein 0.0034 0.0077 0.007
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.016 0.041
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0066 0.0159
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0067 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0669 0.1118
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0337 0.0331
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.016 0.0147
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0182 0.0175
Schistosoma mansoni microtubule-associated protein tau 0.1348 0.7483 0.7481
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0029 0.0049
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0281 0.1469 0.3904
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.01 0.0449 0.118
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Echinococcus granulosus dna polymerase kappa 0.0196 0.0992 0.0986
Loa Loa (eye worm) hypothetical protein 0.0429 0.2303 0.2301
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Loa Loa (eye worm) hypothetical protein 0.0049 0.016 0.0159
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0163 0.0157
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0028 0.0056
Echinococcus granulosus protein C ets 2 0.0042 0.0124 0.0117
Brugia malayi hypothetical protein 0.0022 0.0011 0.0005
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0549 0.2978 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0124 0.0117
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0439 0.1155
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0057 0.0207 0.0201
Treponema pallidum ATP-dependent DNA helicase 0.0029 0.005 0.0118
Echinococcus multilocularis ets variant gene 4 0.0042 0.0124 0.0117
Loa Loa (eye worm) glutathione reductase 0.0284 0.1483 0.1482
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0033 0.0069
Echinococcus multilocularis geminin 0.0164 0.081 0.0804
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.1534 0.4076
Loa Loa (eye worm) hypothetical protein 0.0047 0.0153 0.0151
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0103 0.0096
Loa Loa (eye worm) beta-lactamase 0.0039 0.0103 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0701 0.0695
Schistosoma mansoni glutaminase 0.1083 0.5989 0.5986
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0647 0.3531 0.3522
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0153 0.0146
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0026 0.0033 0.0065
Mycobacterium ulcerans beta-lactamase 0.0039 0.0103 0.009
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0109 0.0273
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0037 0.0031
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.0033 0.0026
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1534 0.4076
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0109 0.0331
Schistosoma mansoni gabp alpha 0.0291 0.1526 0.1521
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0669 0.1118
Onchocerca volvulus 0.009 0.0391 0.1578
Brugia malayi nuclear hormone receptor 0.0042 0.0124 0.0117
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0479 0.1525
Schistosoma mansoni alpha-glucosidase 0.0274 0.1429 0.1424
Entamoeba histolytica recQ family helicase, putative 0.0068 0.027 0.0852
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0029 0.0061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0647 0.3531 0.3522
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0017 0.001
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.016 0.0496
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Loa Loa (eye worm) hypothetical protein 0.0053 0.0182 0.0181
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.008 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Brugia malayi transcription factor E74 isoform 0.0042 0.0124 0.0117
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0549 0.2978 0.2968
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0109 0.0273
Loa Loa (eye worm) MBCTL1 0.0053 0.0182 0.0181
Echinococcus multilocularis lysosomal alpha glucosidase 0.0318 0.1679 0.1674
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0057 0.0207 0.0201
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.008 0.0067
Schistosoma mansoni blooms syndrome DNA helicase 0.0082 0.0347 0.0341
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0103 0.009
Leishmania major hypothetical protein, conserved 0.0026 0.0033 0.0069
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.0956 0.095
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0124 0.0117
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0026 0.0033 0.0026
Onchocerca volvulus Alhambra homolog 0.0058 0.0212 0.0792
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0124 0.0117
Brugia malayi 6-phosphofructokinase 0.0105 0.0479 0.0472
Treponema pallidum oxidoreductase 0.0026 0.0033 0.0063
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0103 0.009
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1189 0.1986
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0009 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0191 0.0963 0.0957
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.0077 0.0187
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0479 0.126
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0077 0.0075
Echinococcus granulosus importin subunit beta 1 0.0029 0.005 0.0043
Plasmodium falciparum phd finger protein, putative 0.0058 0.0212 0.0549
Schistosoma mansoni flap endonuclease-1 0.0023 0.0014 0.0007
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0071 0.007
Schistosoma mansoni ets-related 0.0042 0.0124 0.0117
Echinococcus granulosus ETS transcription factor Elf 5 0.0042 0.0124 0.0117
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Schistosoma mansoni DNA helicase recq5 0.0057 0.0207 0.0201
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0026 0.0034 0.0006
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0046 0.0105
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.016 0.0147
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0153 0.0146
Echinococcus granulosus chromobox protein 1 0.0067 0.0266 0.0259
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0028 0.0046
Plasmodium falciparum importin beta, putative 0.0029 0.005 0.0116
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.0323 0.0844
Brugia malayi Phosphoglycerate kinase 0.0165 0.0814 0.0808
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0019 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0196 0.0992 0.263
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0024 0.0023 0.0044
Schistosoma mansoni DNA helicase recq1 0.0057 0.0207 0.0201
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0098 0.0439 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0036 0.0061
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.0033 0.0069
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0281 0.1469 0.1463
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0103 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0071 0.0119
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0146 0.0499
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0266 0.0264
Leishmania major DNA damage repair protein, putative 0.0053 0.0184 0.0473
Brugia malayi Heterochromatin protein 1 0.0067 0.0266 0.0259
Mycobacterium ulcerans hypothetical protein 0.0039 0.0103 0.009
Echinococcus multilocularis ETS transcription factor Elf 2 0.0042 0.0124 0.0117
Onchocerca volvulus 0.0039 0.0103 0.031
Trypanosoma brucei phosphoglycerate kinase 0.0165 0.0814 0.2156
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0192 0.0186
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.0021
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0479 0.0466
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0026 0.0033 0.0069
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.0033 0.0054
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0029 0.0054
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0196 0.0992 0.1656
Entamoeba histolytica recQ family helicase, putative 0.0028 0.0043 0.0119
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.0339 0.0333
Echinococcus multilocularis peregrin 0.0064 0.0245 0.0238
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0612 0.0611
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0391 0.0389
Trichomonas vaginalis DNA polymerase eta, putative 0.0196 0.0992 0.1656
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0013 0.0018
Mycobacterium tuberculosis Probable oxidoreductase 0.0719 0.3937 0.3929
Schistosoma mansoni sulfide quinone reductase 0.0026 0.0033 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Brugia malayi steroid hormone receptor 0.0042 0.0124 0.0117
Schistosoma mansoni glutamate synthase 0.0026 0.0033 0.0026
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.0033 0.0054
Brugia malayi Bromodomain containing protein 0.0081 0.0343 0.0337
Onchocerca volvulus 0.0039 0.0103 0.031
Schistosoma mansoni dihydrofolate reductase 0.1795 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0124 0.0122
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0034 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0099 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0329 0.0861
Schistosoma mansoni heat shock protein 0.0032 0.0066 0.0059
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0026 0.0033 0.0026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.016 0.0496
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0103 0.009
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.005 0.0115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0124 0.0117
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0146 0.0139
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0101 0.0452 0.119
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0057 0.0207 0.0201
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0479 0.126
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Plasmodium vivax JmjC domain containing protein 0.0034 0.0077 0.0187
Treponema pallidum licC protein (licC) 0.0101 0.0452 0.1422
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0124 0.0402
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0042 0.0124 0.0117
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0109 0.0108
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0062 0.0104
Trypanosoma brucei glucosidase, putative 0.0071 0.0284 0.0739
Loa Loa (eye worm) transcription factor SMAD2 0.0236 0.1218 0.1217
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Giardia lamblia Phosphoglycerate kinase 0.0165 0.0814 0.2608
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0029 0.0016
Brugia malayi PHD-finger family protein 0.0026 0.0032 0.0025
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.0323 0.0844
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0034 0.0056
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0686 0.3753 1
Echinococcus multilocularis ewsr:fli fusion protein type 0.0042 0.0124 0.0117
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.005 0.0116
Echinococcus multilocularis heat shock protein 0.0032 0.0066 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0165 0.0814 0.136
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0247 0.1277 0.1271
Schistosoma mansoni importin beta-1 0.0029 0.005 0.0043
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0549 0.2978 0.2968
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Entamoeba histolytica recQ family DNA helicase 0.0029 0.005 0.0139
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0479 0.0477
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0266 0.0444
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0026 0.0033 0.0026
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0013 0.0018
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0109 0.0273
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0026 0.0033 0.0084
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0182 0.0175
Loa Loa (eye worm) hypothetical protein 0.008 0.0339 0.0338
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0098 0.0439 0.0427
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.0033 0.0084
Schistosoma mansoni hypothetical protein 0.008 0.0337 0.0331
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0033 0.0069
Schistosoma mansoni ap endonuclease 0.004 0.0109 0.0102
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0165 0.0814 0.2702
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0279 0.1457 0.1446
Echinococcus granulosus alkaline phosphatase 0.0157 0.0773 0.0767
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0029 0.0049
Onchocerca volvulus Serine\/threonine kinase homolog 0.0281 0.1469 0.6328
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.0847 0.0835
Trichomonas vaginalis DNA helicase recq1, putative 0.0111 0.0512 0.0854
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0647 0.3531 0.3522
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0124 0.0117
Brugia malayi PHD-finger family protein 0.0058 0.0212 0.0206
Loa Loa (eye worm) glutaminase 0.1083 0.5989 0.5988
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.027 0.0704
Echinococcus granulosus dihydrofolate reductase 0.1795 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0153 0.0146
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0124 0.0117
Leishmania major importin beta-1 subunit, putative 0.0024 0.0019 0.0033
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0103 0.009
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0109 0.0323
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0041 0.0116 0.0109
Loa Loa (eye worm) hypothetical protein 0.0165 0.0814 0.0813
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0019 0.0032
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0066 0.0192
Trypanosoma brucei unspecified product 0.019 0.0956 0.2534
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0028 0.0056
Echinococcus multilocularis chromobox protein 1 0.0067 0.0266 0.0259
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0095 0.0094
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0098 0.0439 0.0427
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0124 0.0122
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0046 0.0105
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.0077 0.0187
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.005 0.0115
Plasmodium falciparum thioredoxin reductase 0.0284 0.1483 0.3942
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0284 0.1483 0.1472
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0117 0.0296
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0098 0.0439 0.1155
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Onchocerca volvulus 0.0429 0.2303 1
Plasmodium falciparum phosphoglycerate kinase 0.0165 0.0814 0.2156
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0062 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.016 0.041
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0479 0.0799
Schistosoma mansoni hypothetical protein 0.008 0.0337 0.0331
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0034 0.0056
Loa Loa (eye worm) hypothetical protein 0.008 0.0337 0.0336
Giardia lamblia DINP protein human, muc B family 0.0177 0.0883 0.283
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0066 0.0159
Schistosoma mansoni glutamate synthase 0.0026 0.0033 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0701 0.0695
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0029 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.019 0.0956 0.2534
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0046 0.0105
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0212 0.0211
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0028 0.0043 0.0098
Brugia malayi mbt repeat family protein 0.0046 0.0146 0.0139
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0612 0.0606
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0701 0.0695
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0057 0.0207 0.0201
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0066 0.0159
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0103 0.0102
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0647 0.3531 0.3522
Brugia malayi AMP-binding enzyme family protein 0.0049 0.016 0.0154
Mycobacterium ulcerans DNA polymerase IV 0.0196 0.0992 0.098
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0146 0.0139
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0281 0.1469 0.1468
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0037 0.0031
Plasmodium falciparum DNA repair protein REV1, putative 0.0053 0.0184 0.0473
Brugia malayi hypothetical protein 0.0022 0.0011 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0479 0.1525
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0689 0.0683
Plasmodium falciparum thioredoxin reductase 0.0098 0.0439 0.1155
Mycobacterium ulcerans hypothetical protein 0.0154 0.0754 0.0741
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0284 0.0473
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.1795 1 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Leishmania major NADH dehydrogenase, putative 0.0026 0.0033 0.0069
Brugia malayi ImpB/MucB/SamB family protein 0.0195 0.0986 0.098
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0124 0.0117
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0098 0.0439 0.1155
Plasmodium vivax SET domain protein, putative 0.0031 0.0059 0.0141
Echinococcus granulosus expressed protein 0.0033 0.0071 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0124 0.0117
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0124 0.0117
Brugia malayi Ets-domain containing protein 0.0291 0.1526 0.1521
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0479 0.1525
Brugia malayi RNA, U transporter 1 0.0083 0.0353 0.0347
Onchocerca volvulus 0.0046 0.0146 0.0499
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0284 0.0473
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0686 0.3753 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0124 0.0122
Trypanosoma brucei phosphoglycerate kinase 0.006 0.0226 0.0587
Loa Loa (eye worm) hypothetical protein 0.0043 0.0127 0.0126
Echinococcus granulosus ETS transcription factor Elf 2 0.0042 0.0124 0.0117
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0028 0.0056
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0011 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0103 0.0257
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0318 0.1679 0.1678
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0011 0.0005
Schistosoma mansoni DNA polymerase IV / kappa 0.0053 0.0184 0.0177
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0612 0.0606
Plasmodium vivax endoplasmin, putative 0.0032 0.0066 0.0159
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.0033 0.0084
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0103 0.009
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.0033 0.0026
Echinococcus granulosus lysosomal alpha glucosidase 0.0318 0.1679 0.1674
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0571 0.3103 1
Trypanosoma brucei polo-like protein kinase 0.0281 0.1469 0.3904
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.1534 0.4076
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0115 0.0192
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0048 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0124 0.0117
Echinococcus granulosus phd:f box containing protein 0.0034 0.0077 0.007
Leishmania major alpha glucosidase II subunit, putative 0.0071 0.0284 0.0739
Loa Loa (eye worm) RecQ helicase 0.0111 0.0512 0.051
Trypanosoma brucei NADH dehydrogenase 0.0026 0.0033 0.0069
Schistosoma mansoni cpg binding protein 0.009 0.0391 0.0384
Trypanosoma brucei unspecified product 0.0118 0.0549 0.1447
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0146 0.0139
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0091 0.0225
Schistosoma mansoni hypothetical protein 0.0311 0.1641 0.1635
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0479 0.0477
Schistosoma mansoni cpg binding protein 0.0097 0.043 0.0424
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0109 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.0585 0.1543
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0033 0.0069
Schistosoma mansoni jumonji domain containing protein 0.0208 0.1057 0.1051
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0109 0.0102
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0247 0.1277 0.1271
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0157 0.0773 0.0767
Echinococcus multilocularis neutral alpha glucosidase AB 0.0071 0.0284 0.0277
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0686 0.3753 1
Echinococcus granulosus dnaJ subfamily B 0.1277 0.708 0.7079
Schistosoma mansoni lipoxygenase 0.0054 0.0192 0.0186
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0026 0.0033 0.0065
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Giardia lamblia Kinase, PLK 0.0281 0.1469 0.4723
Echinococcus granulosus dna polymerase eta 0.0195 0.0986 0.098
Toxoplasma gondii thioredoxin reductase 0.0284 0.1483 0.3942
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0157 0.0773 0.0767
Trypanosoma brucei glycosyl hydrolase-like protein 0.0026 0.0034 0.0073
Brugia malayi Glycosyl hydrolases family 31 protein 0.0071 0.0284 0.0277
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0666 0.1759
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0612 0.0606
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0103 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.1795 1 1
Echinococcus multilocularis alkaline phosphatase 0.0157 0.0773 0.0767
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Brugia malayi Importin beta-1 subunit 0.0029 0.005 0.0043
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0046 0.0105
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0124 0.0117
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0098 0.0439 0.1155
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0042 0.0124 0.0122
Echinococcus granulosus heat shock protein 0.0032 0.0066 0.0059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0109 0.0273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0028 0.0026
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0719 0.3937 0.3929
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Echinococcus multilocularis phd:f box containing protein 0.0034 0.0077 0.007
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0157 0.0773 0.0767
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0046 0.0076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0017 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Toxoplasma gondii exonuclease III APE 0.004 0.0109 0.0273
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0124 0.0117
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0182 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Mycobacterium ulcerans monoxygenase 0.0026 0.0033 0.0019
Loa Loa (eye worm) hypothetical protein 0.0058 0.0212 0.0211
Onchocerca volvulus 0.0231 0.1189 0.5095
Brugia malayi beta-lactamase 0.0039 0.0103 0.0096
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0057 0.0207 0.0536
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.0339 0.0333
Trichomonas vaginalis sucrase-isomaltase, putative 0.0071 0.0284 0.0473
Trypanosoma brucei DNA damage repair protein, putative 0.0053 0.0184 0.0473
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.0585 0.1543
Plasmodium vivax phosphoglycerate kinase, putative 0.0165 0.0814 0.2156
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0266 0.0444
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.0033 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Toxoplasma gondii hypothetical protein 0.0047 0.0151 0.0386
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0033 0.0069
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Loa Loa (eye worm) hypothetical protein 0.0195 0.0986 0.0985
Schistosoma mansoni heat shock protein 0.0032 0.0066 0.0059
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.034 0.0334
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0098 0.0439 0.0433
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0284 0.0473
Echinococcus multilocularis zinc finger protein 0.0028 0.0041 0.0034
Echinococcus multilocularis expressed protein 0.0033 0.0071 0.0064
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0077 0.007
Plasmodium falciparum heat shock protein 90 0.0032 0.0066 0.0159
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0098 0.0439 0.0427
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0011 0.0005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1274 0.1262
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0654 0.0648
Trypanosoma brucei trypanothione reductase 0.0284 0.1483 0.3942
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0124 0.0117
Treponema pallidum fructose-bisphosphate aldolase 0.0571 0.3103 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Echinococcus multilocularis dna polymerase kappa 0.0196 0.0992 0.0986
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0077 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0059 0.0053
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0066 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.016 0.0147
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0124 0.0117
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0046 0.0105
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0103 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.016 0.041
Mycobacterium ulcerans hypothetical protein 0.0053 0.0184 0.0171
Giardia lamblia Thioredoxin reductase 0.0026 0.0033 0.0084
Trypanosoma brucei phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Onchocerca volvulus 0.0042 0.0122 0.0393
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0026 0.0034 0.0073
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0028 0.0068
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.0339 0.0333
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0212 0.0206
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0612 0.1956
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0098 0.0439 0.1155
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.056 0.0559
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0124 0.0117
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0046 0.0106
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0059 0.0141
Leishmania major hypothetical protein, conserved 0.0026 0.0033 0.0069
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0103 0.0096
Schistosoma mansoni phd/f-box containing protein 0.0034 0.0077 0.007
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.006 0.0226 0.0587
Schistosoma mansoni chromobox protein 0.0067 0.0266 0.0259
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0057 0.0207 0.0201
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0066 0.0192
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.009
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0098 0.0439 0.0427
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0097
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0337 0.0331
Loa Loa (eye worm) thioredoxin reductase 0.0284 0.1483 0.1482
Brugia malayi Ets-domain containing protein 0.0042 0.0124 0.0117
Brugia malayi DNA-binding protein D-ETS-3 0.0042 0.0124 0.0117
Toxoplasma gondii NADPH-glutathione reductase 0.0098 0.0439 0.1155
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0124 0.0117
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0098 0.0439 0.1155
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0109 0.0273
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0066 0.0192
Schistosoma mansoni lozenge 0.0054 0.0189 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0184 0.0473
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0701 0.0695
Leishmania major DNA polymerase kappa, putative 0.0177 0.0883 0.2339
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0115 0.0192
Loa Loa (eye worm) endoplasmin 0.0032 0.0066 0.0065
Echinococcus granulosus cpg binding protein 0.0097 0.043 0.0424
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0067 0.016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0042 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.009
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.016 0.0147
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0057 0.0207 0.0206
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0042 0.0124 0.0117
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0131 0.0332
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0165 0.0814 0.2156
Schistosoma mansoni hypothetical protein 0.0042 0.0124 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0124 0.0122
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0026 0.0033 0.0019
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0146 0.0139
Trichomonas vaginalis glutaminase, putative 0.1083 0.5989 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0452 0.044
Echinococcus granulosus glutamate synthase 0.0026 0.0033 0.0026
Schistosoma mansoni glutamate synthase 0.0026 0.0033 0.0026
Brugia malayi PHD-finger family protein 0.0033 0.007 0.0063
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0072 0.0292 0.0286
Entamoeba histolytica serine/threonine protein kinase, putative 0.0281 0.1469 0.4723
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.1795 1 1
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.009
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.0077 0.007
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0103 0.0172
Trichomonas vaginalis DNA helicase recq, putative 0.0068 0.027 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Chlamydia trachomatis thioredoxin reductase 0.0026 0.0033 0.0019
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0165 0.0814 0.2156
Echinococcus granulosus ewsr:fli fusion protein type 0.0042 0.0124 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0701 0.0695
Mycobacterium ulcerans hypothetical protein 0.0026 0.0033 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0059 0.0053
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0071 0.0064
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0124 0.0117
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0026 0.0033 0.0026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0124 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0103 0.0257
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0124 0.0117
Echinococcus multilocularis dna polymerase eta 0.0195 0.0986 0.098
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0026 0.0034 0.0073
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0117 0.0296
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0184 0.0473
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0053 0.0184 0.0473
Mycobacterium ulcerans DNA polymerase IV 0.0196 0.0992 0.098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0124 0.0117
Schistosoma mansoni alpha-glucosidase 0.0274 0.1429 0.1424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Trypanosoma cruzi DNA damage repair protein, putative 0.0053 0.0184 0.0473
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.016 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Brugia malayi Thioredoxin reductase 0.0284 0.1483 0.1478
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0082 0.0075
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0192 0.0186
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0165 0.0814 0.0802
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0091 0.0078
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0182 0.0175
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1032 0.1031
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0109 0.0096
Brugia malayi chromobox protein homolog 3 0.0038 0.0099 0.0092
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0124 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0098 0.0439 0.1155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0124 0.0122
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0013 0.0018
Echinococcus granulosus snurportin 1 0.0311 0.1641 0.1635
Loa Loa (eye worm) acetyltransferase 0.0143 0.0689 0.0688
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0479 0.0466
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Schistosoma mansoni hypothetical protein 0.0289 0.1513 0.1507
Onchocerca volvulus 0.0039 0.0103 0.031
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0028 0.0068
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.016 0.0147
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Plasmodium vivax glutathione reductase, putative 0.0284 0.1483 0.3942
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0177 0.0883 0.0871
Loa Loa (eye worm) hypothetical protein 0.0429 0.2303 0.2301
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0026 0.0033 0.0019
Echinococcus granulosus thioredoxin glutathione reductase 0.0286 0.1498 0.1492
Echinococcus multilocularis phosphoglycerate kinase 1 0.0165 0.0814 0.0808
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0479 0.1507
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0033 0.0069
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0647 0.3531 0.3522
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0284 0.0473
Brugia malayi AMP-binding enzyme family protein 0.0049 0.016 0.0154
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0259 0.0253
Echinococcus multilocularis dihydrofolate reductase 0.1795 1 1
Loa Loa (eye worm) hypothetical protein 0.0385 0.2054 0.2053
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.016 0.0147
Schistosoma mansoni hypothetical protein 0.0164 0.081 0.0804
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0062 0.0104
Echinococcus granulosus heat shock protein 90 0.0032 0.0066 0.0059
Echinococcus multilocularis importin subunit beta 1 0.0029 0.005 0.0043
Trypanosoma brucei DNA polymerase eta, putative 0.0195 0.0986 0.2614
Brugia malayi hypothetical protein 0.0429 0.2303 0.2297
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0131 0.0332
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0153 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.0992 0.263
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.0033 0.0019
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0026 0.0033 0.0026
Brugia malayi 6-phosphofructokinase 0.0105 0.0479 0.0472
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.009
Plasmodium falciparum ferrodoxin reductase-like protein 0.0026 0.0033 0.0069
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0029 0.0061
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0124 0.0117
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0026 0.0033 0.0069
Toxoplasma gondii histone lysine methyltransferase SET1 0.0177 0.0881 0.2334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0124 0.0122
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0701 0.0695
Brugia malayi Fli-1 protein 0.0884 0.4867 0.4864
Brugia malayi AMP-binding enzyme family protein 0.0049 0.016 0.0154
Brugia malayi jmjC domain containing protein 0.0134 0.0641 0.0635
Brugia malayi Glycosyl hydrolases family 31 protein 0.0026 0.0034 0.0027
Trypanosoma cruzi phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Brugia malayi Phosphoglycerate kinase 0.006 0.0226 0.022
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0026 0.0033 0.0084
Schistosoma mansoni hypothetical protein 0.0026 0.0033 0.0026
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0281 0.1469 0.1463
Echinococcus granulosus zinc finger protein 0.0028 0.0041 0.0034
Trichomonas vaginalis glutathione reductase, putative 0.0098 0.0439 0.0733
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0131 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0124 0.0117
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0077 0.0187
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0291 0.1526 0.1525
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0131 0.0332
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0026 0.0033 0.0069
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.0956 0.095
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0101 0.0452 0.044
Echinococcus multilocularis ETS transcription factor Elf 2 0.0042 0.0124 0.0117
Loa Loa (eye worm) hypothetical protein 0.0068 0.0271 0.027
Trypanosoma brucei phosphoglycerate kinase 0.0165 0.0814 0.2156
Mycobacterium ulcerans phosphoglycerate kinase 0.0165 0.0814 0.0802
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0046 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0124 0.0117
Brugia malayi glutathione reductase 0.0284 0.1483 0.1478
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.003
Treponema pallidum phosphoglycerate kinase 0.0165 0.0814 0.2592
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0029 0.0073
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Echinococcus multilocularis bloom syndrome protein 0.0111 0.0512 0.0505
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0165 0.0814 0.0802
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0026 0.0033 0.0019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0103 0.0096
Toxoplasma gondii selenide, water dikinase 0.0026 0.0033 0.0069
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0026 0.0033 0.0084
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0701 0.07
Trypanosoma cruzi polo-like protein kinase, putative 0.0281 0.1469 0.3904
Echinococcus granulosus jumonji domain containing protein 0.0081 0.034 0.0334
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0091 0.0078
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0157 0.0773 0.0767
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0023 0.0044
Leishmania major hypothetical protein, conserved 0.0026 0.0033 0.0069
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Mycobacterium ulcerans hypothetical protein 0.0101 0.0452 0.044
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0033 0.0069
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0686 0.3753 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0171 0.0847 0.2714
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Loa Loa (eye worm) programmed cell death 8 0.0026 0.0033 0.0031
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0212 0.0206
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0026 0.0033 0.0069
Schistosoma mansoni jumonji/arid domain-containing protein 0.0134 0.0641 0.0635
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0124 0.0117
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0049 0.016 0.0159
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.0033 0.0054
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0037 0.0031
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0017 0.001
Toxoplasma gondii ABC1 family protein 0.0039 0.0103 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0284 0.0739
Echinococcus granulosus phosphoglycerate kinase 1 0.0165 0.0814 0.0808
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0479 0.0472
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0171 0.0847 0.0846
Giardia lamblia Glutamate synthase 0.0026 0.0033 0.0084
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.0033 0.0019
Treponema pallidum thioredoxin reductase (trxB) 0.0026 0.0033 0.0063
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.005 0.0043
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0019 0.0032
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0026 0.0033 0.0019
Leishmania major DNA polymerase kappa, putative 0.0053 0.0184 0.0473
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.0033 0.0019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0098 0.0439 0.0433
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0071 0.0284 0.0282
Trypanosoma cruzi DNA polymerase kappa, putative 0.0196 0.0992 0.263
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0329 0.0861
Echinococcus multilocularis Protein lozenge 0.0054 0.0189 0.0182
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0026 0.0033 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0034 0.0056
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0182 0.0175
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0124 0.0117
Brugia malayi Ets-domain containing protein 0.0291 0.1526 0.1521
Echinococcus multilocularis thioredoxin glutathione reductase 0.0286 0.1498 0.1492
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0066 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.008 0.0067
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0306 0.03
Schistosoma mansoni endoplasmin 0.0032 0.0066 0.0059
Brugia malayi Endoplasmin precursor 0.0032 0.0066 0.0059
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0171 0.0847 0.0841
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0026 0.0033 0.0054
Onchocerca volvulus 0.0042 0.0124 0.0402
Trichomonas vaginalis rotamase, putative 0.0032 0.0067 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.008 0.0067
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0098 0.0439 0.1155
Trichomonas vaginalis ran, putative 0.0021 0.0007 0.0011
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0165 0.0814 0.136
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0549 0.2978 0.2968
Echinococcus multilocularis GA binding protein alpha chain 0.0291 0.1526 0.1521
Schistosoma mansoni zinc finger protein 0.0028 0.0041 0.0034
Schistosoma mansoni coup transcription factor 0.0042 0.0124 0.0117
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0034 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0051
Schistosoma mansoni bromodomain containing protein 0.007 0.0279 0.0273
Schistosoma mansoni hypothetical protein 0.1277 0.708 0.7079
Echinococcus granulosus flap endonuclease 1 0.0025 0.0028 0.0021
Echinococcus granulosus GA binding protein alpha chain 0.0291 0.1526 0.1521
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0099 0.0246
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.0033 0.0019
Loa Loa (eye worm) hypothetical protein 0.0079 0.0329 0.0328
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.0033 0.0069
Schistosoma mansoni terminal deoxycytidyl transferase 0.0171 0.0847 0.0841
Trichomonas vaginalis maltase-glucoamylase, putative 0.0026 0.0034 0.0056
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0026 0.0033 0.0069
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0029 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0033 0.0069
Mycobacterium tuberculosis Conserved protein 0.0039 0.0103 0.009
Entamoeba histolytica disulphide oxidoreductase, putative 0.0026 0.0033 0.0084
Schistosoma mansoni protein phosphatase 2C 0.0034 0.0077 0.007
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0279 0.1457 0.1446
Plasmodium falciparum glutathione reductase 0.0284 0.1483 0.3942
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0066 0.0159
Chlamydia trachomatis phosphoglycerate kinase 0.0165 0.0814 0.0802
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0284 0.0473
Loa Loa (eye worm) hypothetical protein 0.0046 0.0146 0.0145
Trichomonas vaginalis esterase, putative 0.0039 0.0103 0.0172
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.0077 0.007
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0046 0.0105
Echinococcus granulosus heat shock protein 90 0.0025 0.0029 0.0023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0124 0.0117
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0103 0.009
Brugia malayi polk-prov protein 0.0079 0.0329 0.0323
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0124 0.0117
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0479 0.0472
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0072 0.0291 0.0759
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0071 0.0284 0.0739
Brugia malayi heat shock protein 90 0.0032 0.0066 0.0059
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0029 0.0016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0117 0.0296
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0103 0.0257
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0337 0.0331
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0284 0.0894
Schistosoma mansoni alpha glucosidase 0.0071 0.0284 0.0277
Trypanosoma cruzi polo-like protein kinase, putative 0.0281 0.1469 0.3904
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0098 0.0439 0.1155
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0026 0.0033 0.0019
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.016 0.0147
Leishmania major glycosyl hydrolase-like protein 0.0026 0.0034 0.0073
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.016 0.0496
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.0641 0.064
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Trypanosoma brucei chrX additional, unordered contigs 0.0053 0.0184 0.0473
Schistosoma mansoni disulfide oxidoreductase 0.0026 0.0033 0.0026
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0165 0.0814 0.2156
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0049 0.016 0.0159
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0046 0.0076
Schistosoma mansoni phosphoglycerate kinase 0.0165 0.0814 0.0808
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.1469 0.2453
Onchocerca volvulus 0.008 0.0339 0.1351
Schistosoma mansoni phosphoglycerate kinase 0.0165 0.0814 0.0808
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0284 0.0473
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.027 0.0704
Echinococcus multilocularis snurportin 1 0.0311 0.1641 0.1635
Trypanosoma brucei DNA polymerase IV, putative 0.0196 0.0992 0.263
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0571 0.3103 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0098 0.0439 0.1155
Brugia malayi jmjC domain containing protein 0.0034 0.0077 0.007
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0066 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0001 0.0001
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.0033 0.0069
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0046 0.0127
Trypanosoma cruzi DNA polymerase eta, putative 0.0195 0.0986 0.2614
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.005 0.0115
Schistosoma mansoni kinase 0.0143 0.069 0.0684
Schistosoma mansoni sulfide quinone reductase 0.0026 0.0033 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0284 0.0473
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0057 0.0207 0.0536
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.0033 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0719 0.3937 0.3929
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0103 0.0257
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.0077 0.007
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0284 0.0894
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Loa Loa (eye worm) hypothetical protein 0.0042 0.0124 0.0122
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0212 0.0549
Leishmania major trypanothione reductase 0.0284 0.1483 0.3942
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0026 0.0033 0.0019
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.1641 0.164
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0103 0.0172
Trypanosoma brucei heat shock protein, putative 0.0032 0.0066 0.0159
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0686 0.3753 1
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.0077 0.007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0134 0.0641 0.0635
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0046 0.0033
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0057 0.0207 0.0536
Echinococcus granulosus ETS transcription factor Elf 2 0.0042 0.0124 0.0117
Loa Loa (eye worm) runx1 0.0054 0.0189 0.0187
Loa Loa (eye worm) hypothetical protein 0.0039 0.0103 0.0102
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0124 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0571 0.3103 0.5182
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0124 0.0122
Leishmania major heat shock protein 83-1 0.0032 0.0066 0.0159
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0013 0.0018
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0098 0.0439 0.1155
Entamoeba histolytica hypothetical protein 0.0024 0.0019 0.004
Trypanosoma brucei DNA polymerase IV, putative 0.0196 0.0992 0.263
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0612 0.1617
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0033 0.0069
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0066 0.0159
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0098 0.0439 0.1155
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0026 0.0033 0.0019
Trypanosoma cruzi phosphoglycerate kinase, putative 0.006 0.0226 0.0587
Loa Loa (eye worm) fli-1 protein 0.0884 0.4867 0.4867
Echinococcus multilocularis dnaJ subfamily B 0.1277 0.708 0.7079
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.0077 0.0187
Loa Loa (eye worm) hypothetical protein 0.0249 0.1288 0.1287
Schistosoma mansoni alkaline phosphatase 0.0157 0.0773 0.0767
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.016 0.0147
Leishmania major DNA polymerase eta, putative 0.0195 0.0986 0.2614
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.0077 0.0187
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0057 0.0207 0.0201
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0131 0.0125
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0647 0.3531 0.3522
Loa Loa (eye worm) hypothetical protein 0.0115 0.0531 0.053
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0612 0.1617
Brugia malayi Bromodomain containing protein 0.0064 0.0245 0.0238
Brugia malayi jmjC domain containing protein 0.0034 0.0077 0.007
Plasmodium vivax DNA repair protein REV1, putative 0.0053 0.0184 0.0473
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0212 0.0206

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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