Detailed information for compound 1765896

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 606.061 | Formula: C30H36ClNO10
  • H donors: 4 H acceptors: 7 LogP: 3.86 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)[C@H]1c2cc3c(c(c2[C@@H](C[C@@]1(O)CC)OC1OC(C)C(C(C1)N(C)C)O)O)C(=O)c1c(C3=O)cccc1O.Cl
  • InChi: 1S/C30H35NO10.ClH/c1-6-30(38)12-19(41-20-11-17(31(3)4)25(33)13(2)40-20)22-15(24(30)29(37)39-5)10-16-23(28(22)36)27(35)21-14(26(16)34)8-7-9-18(21)32;/h7-10,13,17,19-20,24-25,32-33,36,38H,6,11-12H2,1-5H3;1H/t13?,17?,19-,20?,24-,25?,30+;/m1./s1
  • InChiKey: KTSRCTOUNGGQEI-VXVKHNLLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis beta 1 syntrophin 0.0048 0.0165 0.0165
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0009 0.0345
Schistosoma mansoni serine/threonine protein kinase 0.2267 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0112 0.4398
Echinococcus granulosus regulator of G protein signaling 3 0.0305 0.13 0.13
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0048 0.0165 0.0165
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0004 0.0009
Echinococcus multilocularis Pleckstrin y 0.0048 0.0165 0.0165
Echinococcus granulosus bloom syndrome protein 0.0024 0.0056 0.0056
Schistosoma mansoni serine/threonine-protein kinase 0.0056 0.0197 0.0197
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0048 0.0165 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0121 0.0121
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.0717
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0004 0.0009
Loa Loa (eye worm) acetyltransferase 0.0144 0.0586 0.0586
Loa Loa (eye worm) oxysterol binding protein 0.0048 0.0165 0.0165
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0112 0.074
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.1514 1
Schistosoma mansoni hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Brugia malayi MAX-1A 0.0048 0.0165 0.037
Schistosoma mansoni ferritin 0.0017 0.0024 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Brugia malayi Dynamin 0.0048 0.0165 0.037
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0004 0.0004
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0048 0.0165 0.8353
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0004 0.0004
Brugia malayi Cadps2 protein 0.0048 0.0165 0.037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0281 0.0281
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0051 0.0705
Leishmania major protein kinase, putative 0.0056 0.0197 0.8735
Leishmania major DNA polymerase eta, putative 0.0037 0.0112 0.4962
Schistosoma mansoni apoferritin-2 0.0017 0.0024 0.0024
Echinococcus granulosus Oxysterol binding protein 11 0.0048 0.0165 0.0165
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0056 0.0197 0.1302
Schistosoma mansoni hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0197 0.7746
Schistosoma mansoni serine/threonine protein kinase 0.1016 0.4454 0.4454
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0056 0.0197 0.1302
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus granulosus ferritin 0.0017 0.0024 0.0024
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0137 0.695
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0084
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.1514 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0076 0.0076
Brugia malayi ecdysteroid receptor 0.0012 0.0004 0.0009
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0048 0.0165 0.0165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0148 0.0977
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0226 0.0226
Plasmodium falciparum calcium-dependent protein kinase 7 0.0056 0.0197 1
Entamoeba histolytica hypothetical protein 0.0011 0.000000000043743 0.00000000028885
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0586 0.0586
Onchocerca volvulus 0.0058 0.0208 0.2096
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0148 0.0975
Schistosoma mansoni axis inhibition protein axin 0.0305 0.13 0.13
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0004 0.0004
Echinococcus granulosus axis inhibition protein axin 0.0305 0.13 0.13
Trypanosoma cruzi DNA polymerase kappa, putative 0.0069 0.0254 1
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0004 0.0147
Schistosoma mansoni regulator of G protein signaling 0.0305 0.13 0.13
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0051 0.0309
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0004 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Echinococcus multilocularis oxysterol binding protein 1 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0011 0.0000000054881 0.000000055268
Schistosoma mansoni DNA helicase recq5 0.0024 0.0056 0.0056
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1216 0.1216
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0712 0.3104 0.3104
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0 0.0014
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1016 0.4454 0.4454
Echinococcus granulosus regulator of G protein signaling 7 0.0305 0.13 0.13
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0112 0.0112
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0226 0.2918
Loa Loa (eye worm) hypothetical protein 0.0121 0.0488 0.0488
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0051 0.0114
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0112 0.4959
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0305 0.13 0.13
Echinococcus granulosus Rho GTPase activating protein 24 0.0048 0.0165 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma brucei protein kinase, putative 0.0056 0.0197 0.7746
Echinococcus granulosus oxysterol binding protein 3 0.0048 0.0165 0.0165
Echinococcus multilocularis regulator of G protein signaling 0.0305 0.13 0.13
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0665 0.0665
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0165 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0048 0.0165 0.1088
Echinococcus granulosus pleckstrin y domain containing family A 0.0048 0.0165 0.0165
Schistosoma mansoni serine/threonine-protein kinase 0.0056 0.0197 0.0197
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0056 0.2842
Trichomonas vaginalis centaurin alpha, putative 0.0048 0.0165 0.1088
Brugia malayi A-kinase anchor protein 10, precursor 0.0305 0.13 0.2919
Schistosoma mansoni serine/threonine protein kinase 0.2267 1 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0305 0.13 0.2919
Schistosoma mansoni cpg binding protein 0.0035 0.0104 0.0104
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0165 0.8353
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0165 0.0165
Echinococcus multilocularis Pleckstrin y 0.0048 0.0165 0.0165
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0056 0.2473
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0004 0.0009
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0056 0.0197 0.8735
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0712 0.3104 0.6969
Toxoplasma gondii hypothetical protein 0.0048 0.0165 0.6296
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0051 0.3032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Schistosoma mansoni dynamin 0.0048 0.0165 0.0165
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0494 0.2139 0.2139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0665 0.0665
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0197 0.7746
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0009 0.006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0151 0.0151
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0712 0.3104 0.3104
Brugia malayi Dynamin 0.0048 0.0165 0.037
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0024 0.0135
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0121 0.08
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0714 1
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0004 0.0004
Onchocerca volvulus Huntingtin homolog 0.0121 0.0488 0.4911
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.0717
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0048 0.0165 0.0165
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0165 0.1088
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0024 0.0337
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0056 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0147 0.579
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0137 0.0905
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0121 0.6159
Trichomonas vaginalis ferritin, putative 0.0017 0.0024 0.0161
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0148 0.0148
Schistosoma mansoni apoferritin-2 0.0017 0.0024 0.0024
Brugia malayi chromobox protein homolog 3 0.0039 0.0121 0.0272
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0148 0.0148
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0148 0.0148
Plasmodium vivax hypothetical protein, conserved 0.0011 0.000000000043743 0.0000000022185
Echinococcus granulosus Pleckstrin y 0.0048 0.0165 0.0165
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0004 0.0004
Echinococcus granulosus Chromobox protein 3 0.0011 0.0000000054881 0.0000000054881
Schistosoma mansoni cpg binding protein 0.0037 0.0112 0.0112
Leishmania major protein kinase, putative 0.0056 0.0197 0.8735
Echinococcus multilocularis cpg binding protein 0.0037 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Brugia malayi Syntrophin-1 0.0048 0.0165 0.037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0048 0.0165 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0165 0.037
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0056 0.037
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0004 0.0009
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Entamoeba histolytica hypothetical protein 0.0048 0.0165 0.1088
Loa Loa (eye worm) hypothetical protein 0.0081 0.0309 0.0309
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0305 0.13 0.13
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0586 0.1316
Echinococcus multilocularis regulator of G protein signaling 3 0.0305 0.13 0.13
Toxoplasma gondii Oxysterol-binding protein 0.0048 0.0165 0.6296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0112 1
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0165 0.1088
Echinococcus multilocularis Rho GTPase activating protein 24 0.0048 0.0165 0.0165
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0104 0.0104
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0056 0.0197 0.8735
Echinococcus granulosus calcium dependent secretion activator 1 0.0048 0.0165 0.0165
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Entamoeba histolytica hypothetical protein 0.0023 0.0051 0.0337
Brugia malayi Pleckstrin Homology Domain 0.0048 0.0165 0.037
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0095 0.1025
Brugia malayi Regulator of G protein signaling domain containing protein 0.0305 0.13 0.2919
Echinococcus multilocularis dynamin 1 0.0048 0.0165 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0004 0.0009
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0148
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0109 0.4263
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.023
Onchocerca volvulus 0.0081 0.0309 0.3113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0004 0.0004
Echinococcus granulosus G protein coupled receptor kinase 1 0.1963 0.865 0.865
Trypanosoma brucei DNA polymerase eta, putative 0.0037 0.0112 0.44
Brugia malayi hypothetical protein 0.0048 0.0165 0.037
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2267 1 1
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni hypothetical protein 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0048 0.0165 0.1659
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0056 0.0056
Schistosoma mansoni zinc finger protein 0.0048 0.0165 0.0165
Echinococcus multilocularis ferritin 0.0017 0.0024 0.0024
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0 0.0011
Echinococcus multilocularis pleckstrin y domain containing family A 0.0048 0.0165 0.0165
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0056 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Entamoeba histolytica PH domain containing protein 0.0048 0.0165 0.1088
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Schistosoma mansoni alpha-glucosidase 0.0139 0.0565 0.0565
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0048 0.0165 0.6469
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0717
Brugia malayi SET domain containing protein 0.0013 0.0008 0.0018
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0095 0.1025
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Echinococcus multilocularis cytohesin 1 0.0048 0.0165 0.0165
Echinococcus multilocularis Regulator of G protein signaling 20 0.0305 0.13 0.13
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Brugia malayi follicle stimulating hormone receptor 0.0231 0.0972 0.2183
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Onchocerca volvulus Protein melted homolog 0.0048 0.0165 0.1659
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0665 0.1493
Loa Loa (eye worm) rho-GTPase-activating 0.0048 0.0165 0.0165
Echinococcus multilocularis tumor protein p63 0.0408 0.1759 0.1759
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0112 0.0252
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0051 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0215 0.0215
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0109 0.0717
Entamoeba histolytica hypothetical protein 0.0048 0.0165 0.1088
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0048 0.0165 0.8353
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0151 0.0151
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0165 0.1088
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0112 0.4284
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0004 0.0009
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0056 0.2142
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0004 0.0009
Schistosoma mansoni ferritin light chain 0.0017 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0056 0.0197 0.1302
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0148 0.5807
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0004 0.0009
Schistosoma mansoni growth factor receptor-bound protein 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0143 0.56
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0712 0.3104 0.3104
Schistosoma mansoni ap endonuclease 0.0023 0.0051 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Brugia malayi regulator of G-protein signaling rgs-7 0.0305 0.13 0.2919
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0097 0.3809
Echinococcus granulosus dynamin 1 0.0048 0.0165 0.0165
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.000000000043743 0.0000000022185
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0045 0.0147 0.1784
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0717
Trypanosoma cruzi DNA polymerase kappa, putative 0.0069 0.0254 1
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0048 0.0165 0.8353
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0148 0.0332
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0004 0.0004
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0056 0.0197 0.7746
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0112 0.4398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0305 0.13 0.13
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0004 0.0204
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0004 0.0041
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0009 0.006
Trichomonas vaginalis alpha chimerin, putative 0.0048 0.0165 0.1088
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0084 0.0084
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0009 0.0091
Echinococcus multilocularis calcium dependent secretion activator 1 0.0048 0.0165 0.0165
Schistosoma mansoni ap endonuclease 0.0023 0.0051 0.0051
Plasmodium falciparum oxysterol-binding protein, putative 0.0048 0.0165 0.8353
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus multilocularis Ras associated and pleckstrin y 0.0048 0.0165 0.0165
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0036 0.1361
Echinococcus granulosus chromobox protein 1 0.0069 0.0256 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0109 0.0717
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0165 0.6469
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0048 0.0165 0.0165
Echinococcus granulosus regulator of G protein signaling 3 0.0305 0.13 0.13
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0165 0.0165
Trypanosoma cruzi DNA polymerase kappa, putative 0.0069 0.0254 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0197 0.7746
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0004 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0004 0.0041
Brugia malayi PXA domain containing protein 0.0305 0.13 0.2919
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Echinococcus granulosus microtubule associated protein 2 0.0833 0.3644 0.3644
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0004 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.1514 1
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Brugia malayi regulator of G-protein signaling egl-10 0.0305 0.13 0.2919
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0048 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0121 0.0488 0.0488
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0009 0.002
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0009 0.0009
Schistosoma mansoni z-protein (S1r protein) 0.0305 0.13 0.13
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0256 0.1689
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0051 0.071
Onchocerca volvulus 0.006 0.0215 0.2162
Plasmodium falciparum PH domain-containing protein, putative 0.0048 0.0165 0.8353
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0004 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Onchocerca volvulus Huntingtin homolog 0.0121 0.0488 0.4911
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0048 0.0165 0.0165
Trypanosoma cruzi DNA polymerase kappa, putative 0.0069 0.0254 1
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0056 0.0197 0.7746
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0121 0.1222
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0019 0.0123
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0056 0.0197 0.7746
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma brucei unspecified product 0.0025 0.0062 0.242
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Echinococcus multilocularis rac serine:threonine kinase 0.0056 0.0197 0.0197
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0051 0.0051
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0165 0.1088
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0586 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Brugia malayi Pre-SET motif family protein 0.003 0.0084 0.0189
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0051 0.0385
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0004 0.0004
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0309 0.0309
Brugia malayi polk-prov protein 0.0043 0.0143 0.032
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0048 0.0165 0.1088
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0097 0.3809
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0112 0.0252
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0714 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0226 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0009 0.006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0305 0.13 0.13
Echinococcus granulosus expressed protein 0.0017 0.0024 0.0024
Schistosoma mansoni inositol monophosphatase 0.0037 0.0112 0.0112
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0165 0.1088
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0048 0.0165 0.1659
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0056 0.2193
Echinococcus multilocularis DCC interacting protein 13 beta 0.0048 0.0165 0.0165
Brugia malayi CHD4 protein 0.0013 0.0009 0.002
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0197 0.7746
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0004 0.0004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0151 0.0151
Schistosoma mansoni dynamin 0.0048 0.0165 0.0165
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0051 0.0334
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1963 0.865 0.865
Onchocerca volvulus 0.0048 0.0165 0.1659
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0305 0.13 0.13
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni ferritin 0.0017 0.0024 0.0024
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0137 0.5238
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0051 0.2567
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0009 0.006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0148 0.0977
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0000000054881 0.0000000054881
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0004 0.0004
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0056 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0712 0.3104 0.3104
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0148 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0004 0.0004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0148 0.6549
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0226 0.0226
Brugia malayi Uncoordinated protein 104 0.0048 0.0165 0.037
Loa Loa (eye worm) inositol-1 0.0037 0.0112 0.0112
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0004 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0256 0.1689
Schistosoma mansoni regulator of G protein signaling 0.0305 0.13 0.13
Schistosoma mansoni regulator of G protein signaling 0.0305 0.13 0.13
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0151 0.0151
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0069 0.0254 0.168
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0004 0.0004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0148 0.5807
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0226 0.0507
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0148 0.5807
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0004 0.0004
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0056 0.2142
Echinococcus multilocularis Oxysterol binding protein 11 0.0048 0.0165 0.0165
Entamoeba histolytica hypothetical protein 0.0305 0.13 0.8584
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0112 0.074
Schistosoma mansoni chromobox protein 0.0069 0.0256 0.0256
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0197 0.7746
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0262 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0143 0.56
Echinococcus multilocularis actin binding protein anillin 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0093 0.0364 0.3661
Trypanosoma brucei rac serine-threonine kinase, putative 0.0056 0.0197 0.7746
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0097 0.3809
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0019 0.0123
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0048 0.0165 0.0165
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Schistosoma mansoni DNA polymerase eta 0.0037 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0121 0.0801
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0009 0.0009
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0714 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0056 0.0197 0.7538
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0148 0.0148
Brugia malayi Protein kinase domain containing protein 0.0056 0.0197 0.0443
Loa Loa (eye worm) AGC/AKT protein kinase 0.0056 0.0197 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Echinococcus granulosus myotubularin protein 13 0.0048 0.0165 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0056 0.0368
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0109 0.4263
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0717
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0148 0.0148
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0165 0.1088
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0165 0.0165
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0084 0.3224
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0084 0.0084
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0197 0.7746
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0004 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0665 0.0665
Loa Loa (eye worm) Plekhf2 protein 0.0048 0.0165 0.0165
Schistosoma mansoni ferritin 0.0017 0.0024 0.0024
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0305 0.13 0.13
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0004 0.0004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0134 0.1353
Schistosoma mansoni regulator of G protein signaling 0.0305 0.13 0.13
Schistosoma mansoni DNA helicase recq1 0.0024 0.0056 0.0056
Trichomonas vaginalis kinesin light chain, putative 0.0048 0.0165 0.1088
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0004 0.0004
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0056 0.0056
Mycobacterium ulcerans DNA polymerase IV 0.0069 0.0254 0.356
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0048 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0048 0.0165 0.0165
Giardia lamblia DINP protein human, muc B family 0.0045 0.0147 0.0972
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0004 0.0004
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0137 0.0905
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0215 0.0215
Schistosoma mansoni ferritin light chain 0.0017 0.0024 0.0024
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0048 0.0165 0.0165
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0112 0.0112
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0009 0.006
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0 0.0011
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0048 0.0165 0.0165
Echinococcus multilocularis oxysterol binding protein 3 0.0048 0.0165 0.0165
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Echinococcus granulosus cytohesin 1 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Echinococcus granulosus regulator of G protein signaling 7 0.0305 0.13 0.13
Echinococcus multilocularis myotubularin protein 13 0.0048 0.0165 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0197 0.7746
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0051 0.0051
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0197 0.7746
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0109 0.0109
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0009 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1216 0.1216
Trypanosoma brucei unspecified product 0.0061 0.0219 0.8611
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Entamoeba histolytica ARF GTPase activating protein, putative 0.0048 0.0165 0.1088
Echinococcus granulosus tumor protein p63 0.0408 0.1759 0.1759
Schistosoma mansoni hypothetical protein 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0048 0.0165 0.1659
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Onchocerca volvulus 0.0235 0.0993 1
Schistosoma mansoni hypothetical protein 0.0058 0.0208 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni zinc finger protein 0.0048 0.0165 0.0165
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0165 0.6469
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0134 0.0887
Onchocerca volvulus 0.0012 0.0004 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0004 0.0009
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0056 0.2842
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0051 0.198
Brugia malayi TBC domain containing protein 0.0048 0.0165 0.037
Brugia malayi Cytohesin 3 0.0048 0.0165 0.037
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0056 0.0056
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0056 0.0197 1
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Echinococcus multilocularis dna polymerase eta 0.0037 0.0112 0.0112
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.000000000043743 0.000000000098203
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0056 0.037
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative 0.0045 0.0147 0.6529
Echinococcus granulosus dnaJ subfamily B 0.0494 0.2139 0.2139
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0165 0.1088
Trichomonas vaginalis hypothetical protein 0.0048 0.0165 0.1088
Toxoplasma gondii phosphatidylinositol transfer protein 0.0048 0.0165 0.6296
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0002 0.0002
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0048 0.0165 0.8353
Echinococcus granulosus Pleckstrin y 0.0048 0.0165 0.0165
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.4153
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0051 0.071
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0051 0.0334
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Echinococcus granulosus axis inhibition protein axin 0.0305 0.13 0.13
Onchocerca volvulus 0.0042 0.0134 0.1353
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0134 0.0134
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.000000000043743 0.000000000043743
Toxoplasma gondii AtPH1 family protein 0.0048 0.0165 0.6296
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0004 0.0041
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1016 0.4454 1
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0165 0.1088
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0056 0.0126
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0134 0.0887
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus granulosus beta 1 syntrophin 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0219 0.8611
Schistosoma mansoni alpha glucosidase 0.0036 0.0109 0.0109
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0109 0.0244
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0051 0.2585
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) syntrophin-1 0.0048 0.0165 0.0165
Echinococcus multilocularis axis inhibition protein axin 0.0305 0.13 0.13
Echinococcus multilocularis regulator of G protein signaling 3 0.0305 0.13 0.13
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0051 0.1948
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0568 0.0568
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0109 0.0717
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0051 0.2585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Brugia malayi Pre-SET motif family protein 0.0207 0.0867 0.1946
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.000000000043743 0.000000000043743
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0035 0.0104 0.1044
Echinococcus granulosus dna polymerase kappa 0.0069 0.0254 0.0254
Leishmania major hypothetical protein, conserved 0.0048 0.0165 0.7295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0151 0.0151
Mycobacterium ulcerans DNA polymerase IV 0.0069 0.0254 0.356
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0051 0.2233
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0051 0.0311
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0048 0.0165 0.0165
Echinococcus granulosus dna polymerase eta 0.0037 0.0112 0.0112
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0051 0.1948
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0051 0.0334
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0226 0.0226
Entamoeba histolytica hypothetical protein 0.0305 0.13 0.8584
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0004 0.0004
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0165 0.0165
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0148 0.0977
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0121 0.0801
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0121 0.0802
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Loa Loa (eye worm) hypothetical protein 0.0286 0.1216 0.1216
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0045 0.0147 0.6529
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Trypanosoma brucei glucosidase, putative 0.0036 0.0109 0.4263
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0048 0.0165 0.0165
Schistosoma mansoni regulator of G protein signaling 0.0305 0.13 0.13
Leishmania major folate/biopterin transporter, putative 0.0056 0.0197 0.8735
Entamoeba histolytica hypothetical protein 0.0048 0.0165 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0004 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0048 0.0165 0.0165
Schistosoma mansoni axis inhibition protein axin 0.0305 0.13 0.13
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0305 0.13 0.13
Echinococcus granulosus expressed protein 0.0305 0.13 0.13
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0004 0.0004
Brugia malayi CXXC zinc finger family protein 0.0035 0.0104 0.0233
Loa Loa (eye worm) PH domain-containing protein 0.0048 0.0165 0.0165
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0009 0.006
Leishmania major serine/threonine-protein kinase a, putative 0.0056 0.0197 0.8735
Echinococcus multilocularis beta adrenergic receptor kinase 0.2267 1 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.1514 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0717
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0148 0.0148
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0009 0.0389
Trichomonas vaginalis DNA polymerase eta, putative 0.0069 0.0254 0.168
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0048 0.0165 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0016 0.0107
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.3644 0.3644
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0165 0.1088
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Echinococcus multilocularis axis inhibition protein axin 0.0305 0.13 0.13
Brugia malayi hypothetical protein 0.0286 0.1216 0.2729
Entamoeba histolytica p21-activated kinase 0.0056 0.0197 0.1302
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0051 0.2248
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0048 0.0165 0.0165
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Brugia malayi nuclear receptor NHR-88 0.0012 0.0004 0.0009
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0165 0.037
Schistosoma mansoni rho gtpase activating protein 0.0048 0.0165 0.0165
Onchocerca volvulus 0.0048 0.0165 0.1659
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0165 0.1088
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.000000000043743 0.000000000098203
Echinococcus multilocularis GRB2 associated binding protein 3 0.0048 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0043 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0048 0.0165 0.1659
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Echinococcus granulosus chromobox protein 1 0.0069 0.0256 0.0256
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.023
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0717
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.3644 0.3644
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0112 0.0112
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0002 0.0004
Echinococcus granulosus pdz domain containing protein 0.0048 0.0165 0.0165
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0048 0.0165 0.0165
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Toxoplasma gondii exonuclease III APE 0.0023 0.0051 0.1935
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0148 0.0977
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0112 0.0112
Echinococcus multilocularis pdz domain containing protein 0.0048 0.0165 0.0165
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.000000000043743 0.000000000043743
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0084
Loa Loa (eye worm) cytohesin 3 0.0048 0.0165 0.0165
Schistosoma mansoni chromobox protein 0.0069 0.0256 0.0256
Brugia malayi steroid hormone receptor 0.0012 0.0004 0.0009
Schistosoma mansoni ferritin 0.0017 0.0024 0.0024
Toxoplasma gondii protein kinase domain-containing protein 0.0056 0.0197 0.7538
Loa Loa (eye worm) RecQ helicase 0.0024 0.0056 0.0056
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.2139 0.2139
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0112 0.074
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0112 0.4398
Loa Loa (eye worm) hypothetical protein 0.0011 0.000000000043743 0.000000000043743
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0148 0.0148
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0109 0.0109
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0665 0.0665
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0004 0.0004
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0109 0.4807
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0069 0.0254 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0208 0.0467
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0009 0.006
Brugia malayi Heterochromatin protein 1 0.0069 0.0256 0.0574
Entamoeba histolytica PH domain containing protein 0.0048 0.0165 0.1088
Echinococcus granulosus serine/threonine protein kinase 0.0056 0.0197 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0471
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0165 0.037
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0165 0.0165
Entamoeba histolytica hypothetical protein 0.0048 0.0165 0.1088
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0305 0.13 0.8584
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0002 0.0013
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0004 0.0027
Trichomonas vaginalis centaurin beta, putative 0.0048 0.0165 0.1088
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0137 0.5238
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0051 0.1994
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0109 0.0717
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0084
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0051 0.038
Loa Loa (eye worm) hypothetical protein 0.0305 0.13 0.13
Echinococcus granulosus Chromo domain 0.0011 0.000000000043743 0.000000000043743
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni centaurin alpha 0.0048 0.0165 0.0165
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0256 0.0256
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0012 0.0002 0.01
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0051 0.5
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0004 0.0004
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0197 0.1302
Echinococcus granulosus Pleckstrin y 0.0048 0.0165 0.0165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0004 0.0154
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0009 0.006
Echinococcus granulosus Regulator of G protein signaling 20 0.0305 0.13 0.13
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.000000000043743 0.0000000016722
Trypanosoma brucei DNA polymerase IV, putative 0.0069 0.0254 1
Echinococcus granulosus cpg binding protein 0.0037 0.0112 0.0112
Onchocerca volvulus 0.0048 0.0165 0.1659
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0165 0.8353
Trichomonas vaginalis conserved hypothetical protein 0.0305 0.13 0.8584
Brugia malayi probable spectrin beta chain 0.0048 0.0165 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0151 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0004 0.0009
Echinococcus multilocularis chromobox protein 1 0.0069 0.0256 0.0256
Echinococcus multilocularis regulator of G protein signaling 7 0.0305 0.13 0.13
Loa Loa (eye worm) hypothetical protein 0.0024 0.0056 0.0056
Echinococcus multilocularis Chromo domain 0.0011 0.000000000043743 0.000000000043743
Onchocerca volvulus Putative zinc finger protein 0.0048 0.0165 0.1659
Brugia malayi PH domain containing protein 0.0048 0.0165 0.037
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0165 0.1088
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0056 0.2193
Brugia malayi hypothetical protein 0.0305 0.13 0.2919
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Entamoeba histolytica PH domain containing protein 0.0048 0.0165 0.1088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0084
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0056 0.0197 0.1302
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0051 0.198
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Schistosoma mansoni cpg binding protein 0.0037 0.0112 0.0112
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0048 0.0165 0.7295
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0056 0.0056
Loa Loa (eye worm) PXA domain-containing protein 0.0305 0.13 0.13
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0051 0.198
Schistosoma mansoni vav2 0.0048 0.0165 0.0165
Echinococcus granulosus oxysterol binding protein 1 0.0048 0.0165 0.0165
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0002 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0471
Brugia malayi Oxysterol-binding protein 0.0048 0.0165 0.037
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0309 0.0309
Echinococcus multilocularis expressed protein 0.0305 0.13 0.13
Entamoeba histolytica hypothetical protein 0.0305 0.13 0.8584
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0309 0.0309
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0004 0.0147
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0867 0.0867
Loa Loa (eye worm) RGS-3 protein 0.0305 0.13 0.13
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0112 0.0112
Schistosoma mansoni alpha-glucosidase 0.0139 0.0565 0.0565
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Brugia malayi Oxysterol binding protein 0.0048 0.0165 0.037
Plasmodium vivax PH domain containing protein 0.0048 0.0165 0.8353
Brugia malayi hypothetical protein 0.0305 0.13 0.2919
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus multilocularis oxysterol binding protein 9 0.0048 0.0165 0.0165
Echinococcus granulosus GRB2 associated binding protein 3 0.0048 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma cruzi Protein kinase B 0.0056 0.0197 0.7746
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.000000000043743 0.000000000043743
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0112 0.44
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0165 0.1088
Onchocerca volvulus 0.0048 0.0165 0.1659
Brugia malayi PXA domain containing protein 0.0305 0.13 0.2919
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0151 0.0338
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0009 0.0345
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.000000000043743 0.00000000028885
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0048 0.0165 0.1088
Schistosoma mansoni coup transcription factor 0.0012 0.0004 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0051 0.0385
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0112 0.1566
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0048 0.0165 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Toxoplasma gondii hypothetical protein 0.0048 0.0165 0.6296
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0056 0.0197 0.7746
Onchocerca volvulus 0.0048 0.0165 0.1659
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0009 0.006
Loa Loa (eye worm) uncoordinated protein 104 0.0048 0.0165 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0254 1
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0056 0.0197 0.7746
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0165 0.6469
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0048 0.0165 0.6469
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0112 0.074
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0048 0.0165 0.6469
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0165 0.8353
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0048 0.0165 0.0165
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0165 0.6469
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0051 0.2567
Schistosoma mansoni syntrophin 0.0048 0.0165 0.0165
Echinococcus multilocularis dna polymerase kappa 0.0069 0.0254 0.0254
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0009 0.0345
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0226 0.3157
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0024 0.0337
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0056 0.0197 0.7746
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0112 0.074
Brugia malayi Inositol-1 0.0037 0.0112 0.0252
Trichomonas vaginalis centaurin gamma, putative 0.0048 0.0165 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0112 0.1272
Schistosoma mansoni survival motor neuron protein 0.0058 0.0208 0.0208
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0165 0.0165
Echinococcus granulosus oxysterol binding protein 9 0.0048 0.0165 0.0165
Brugia malayi hypothetical protein 0.0121 0.0488 0.1095
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Schistosoma mansoni myotubularin-related protein 0.0048 0.0165 0.0165
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0056 0.0197 0.7746
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0197 0.1302
Schistosoma mansoni inositol monophosphatase 0.0037 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Trypanosoma brucei unspecified product 0.0025 0.0062 0.242
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0004 0.0004
Echinococcus multilocularis Pleckstrin y 0.0048 0.0165 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0004 0.0009
Plasmodium vivax SET domain protein, putative 0.003 0.0084 0.4277
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0048 0.0165 0.037
Brugia malayi Plekhf2 protein 0.0048 0.0165 0.037
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0165 0.1088
Echinococcus multilocularis expressed protein 0.0017 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0048 0.0165 0.1088
Onchocerca volvulus 0.003 0.0084 0.0849
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0056 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.023
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0084 0.0084
Trypanosoma cruzi hypothetical protein 0.0048 0.0165 0.6469
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.0972 0.0972
Entamoeba histolytica protein kinase, putative 0.0056 0.0197 0.1302
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0993 0.6557
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0002 0.0002
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0048 0.0165 0.0165
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0004 0.0004
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0056 0.0126
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0051 0.0332
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0309 0.0694
Onchocerca volvulus outspread protein homolog 0.0048 0.0165 0.1659
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0165 0.1088
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0009 0.0009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0109 0.0109
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0226 0.3157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0112
Echinococcus multilocularis chromobox protein 1 0.0069 0.0256 0.0256
Echinococcus granulosus DCC interacting protein 13 beta 0.0048 0.0165 0.0165
Trypanosoma brucei PH domain containing protein, putative 0.0048 0.0165 0.6469
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Brugia malayi nuclear hormone receptor 0.0012 0.0004 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1514 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0051 0.2993

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -7.27 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.761 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.749 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.717 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.658 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.61 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.604 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.566 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.416 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.229 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.171 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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