Detailed information for compound 1782333

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 507.495 | Formula: C25H25N5O7
  • H donors: 3 H acceptors: 5 LogP: 2.15 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C1CCN(CC1)c1ccc(cc1)N1C[C@@H](OC1=O)CNC(=O)c1ccc(cc1)c1noc(=O)[nH]1
  • InChi: 1S/C25H25N5O7/c31-22(16-3-1-15(2-4-16)21-27-24(34)37-28-21)26-13-20-14-30(25(35)36-20)19-7-5-18(6-8-19)29-11-9-17(10-12-29)23(32)33/h1-8,17,20H,9-14H2,(H,26,31)(H,32,33)(H,27,28,34)/t20-/m0/s1
  • InChiKey: GZTPZSKNKZVAKJ-FQEVSTJZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) References
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma mansoni integrin beta subunit Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum Integrin beta-PS precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin beta pat-3 precursor Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06464 integrin beta 2, putative Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus granulosus integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin beta-2 Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum Integrin beta-3 precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0138 0.0792
Schistosoma mansoni glutaminase 0.0549 0.1722 0.1721
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0241 0.0629
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0138 0.0792
Schistosoma mansoni cpg binding protein 0.0187 0.0547 0.0546
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0098 0.057
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0125 0.0348 0.034
Echinococcus granulosus Niemann Pick C1 protein 0.0191 0.056 0.0551
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0176 0.0167
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2368 0.7625 0.7623
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0076 0.0067
Echinococcus granulosus transcription factor Dp 1 0.0077 0.019 0.0182
Trichomonas vaginalis rotamase, putative 0.0033 0.0049 0.0284
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0046 0.0089 0.0768
Brugia malayi ecdysone receptor 0.0029 0.0034 0.0188
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0034 0.0025
Leishmania major DNA polymerase eta, putative 0.009 0.0234 0.0589
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0004
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0052 0.0044
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0126 0.0349 0.0912
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Entamoeba histolytica hypothetical protein 0.0144 0.0408 0.04
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0172 0.0427
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0039 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0044 0.0084 0.0076
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.0725 0.0717
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0186 0.0177
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0176 0.0167
Schistosoma mansoni ap endonuclease 0.0076 0.0186 0.0185
Trichomonas vaginalis esterase, putative 0.0072 0.0176 0.1023
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0194 0.0569 0.0568
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0049 0.0385
Brugia malayi Calcitonin receptor-like protein seb-1 0.0549 0.1722 1
Echinococcus granulosus integrin beta 2 0.028 0.085 0.0842
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0024
Schistosoma mansoni phosphoglycerate kinase 0.0342 0.1052 0.1051
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0027 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0138 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Loa Loa (eye worm) hypothetical protein 0.0375 0.1159 0.1151
Onchocerca volvulus Ceramide kinase 1 homolog 0.0121 0.0333 0.4504
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0342 0.1052 0.1044
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0045 0.0118
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0103 0.0095
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0098 0.0857
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0044 0.0035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0034 0.044
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0009 0.0023
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0045 0.0118
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0174 0.0505 0.0496
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0113 0.0105
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0045 0.0349
Loa Loa (eye worm) hypothetical protein 0.0069 0.0163 0.0155
Loa Loa (eye worm) MBCTL1 0.0057 0.0126 0.0117
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Onchocerca volvulus 0.0029 0.0034 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0163 0.0162
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0126 0.0117
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.002 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0034 0.0025
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0098 0.0857
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0049 0.0128
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0163 0.0155
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0302 0.0294
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0133 0.0372 0.0951
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0138 0.0129
Loa Loa (eye worm) histone methyltransferase 0.0055 0.0118 0.011
Mycobacterium ulcerans diacylglycerol kinase 0.0121 0.0333 0.0324
Schistosoma mansoni blooms syndrome DNA helicase 0.0053 0.0114 0.0112
Onchocerca volvulus 0.0072 0.0176 0.2374
Echinococcus multilocularis sphingosine kinase 1 0.31 1 1
Trypanosoma brucei chrX additional, unordered contigs 0.0039 0.0067 0.0176
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0036 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Mycobacterium tuberculosis Conserved protein 0.0072 0.0176 0.0167
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0055 0.0118 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0176 0.046
Mycobacterium leprae Probable lipase LipE 0.0072 0.0176 0.1603
Echinococcus granulosus lamin dm0 0.0026 0.0026 0.0017
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0031 0.0174
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0081 0.0072
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0035
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0097 0.0095
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0034 0.0025
Brugia malayi Bromodomain containing protein 0.0081 0.0203 0.1171
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0121 0.0333 0.0869
Schistosoma mansoni endoplasmin 0.0032 0.0045 0.0044
Trypanosoma cruzi DNA polymerase eta, putative 0.0177 0.0514 0.1344
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0141 0.0132
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0166 0.0479 0.0471
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0017
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0138 0.0136
Leishmania major GTP-binding protein, putative 0.0021 0.0009 0.0001
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.002 0.0111
Schistosoma mansoni ran 0.0021 0.0009 0.0008
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0166 0.0479 0.0471
Leishmania major hypothetical protein, conserved 0.0024 0.002 0.0029
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0138 0.0129
Trypanosoma brucei ISWI complex protein 0.0031 0.0041 0.0107
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0133 0.0372 0.0972
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0024 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0265 0.0692
Plasmodium falciparum diacylglycerol kinase, putative 0.0121 0.0333 0.3131
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0103 0.1384
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Echinococcus multilocularis transcription factor Dp 1 0.0077 0.019 0.0182
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0087 0.0751
Loa Loa (eye worm) hypothetical protein 0.0057 0.0126 0.0117
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0176 0.1023
Loa Loa (eye worm) hypothetical protein 0.0082 0.0207 0.0198
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0138 0.0136
Echinococcus granulosus ferritin 0.0026 0.0027 0.0018
Mycobacterium ulcerans glutaminase 0.0549 0.1722 0.1715
Plasmodium falciparum DNA repair protein REV1, putative 0.0039 0.0067 0.0596
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0174 0.0505 0.0496
Schistosoma mansoni DNA helicase recq1 0.0028 0.0031 0.003
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0034 0.0188
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0138 0.0136
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0126 0.0117
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.002 0.0019
Trypanosoma cruzi Sphingosine kinase 0.0121 0.0333 0.0869
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0044 0.0035
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0302 0.0294
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0138 0.0129
Trypanosoma brucei phosphoglycerate kinase 0.0342 0.1052 0.2749
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0024 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0067 0.0176
Trichomonas vaginalis DNA polymerase eta, putative 0.0179 0.0522 0.3029
Echinococcus granulosus endoplasmin 0.0026 0.0024 0.0015
Leishmania major phosphoglycerate kinase B, cytosolic 0.0342 0.1052 0.2732
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0035
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.002 0.011
Schistosoma mansoni intermediate filament proteins 0.0026 0.0026 0.0024
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.002 0.0144
Schistosoma mansoni integrin beta subunit 0.0223 0.0664 0.0662
Toxoplasma gondii ImpB/MucB/SamB family protein 0.009 0.0234 0.2155
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0138 0.0792
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0103 0.0095
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.002 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0172 0.0163
Mycobacterium tuberculosis Conserved protein 0.0072 0.0176 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0033 0.0087
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0302 0.0294
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0031 0.0252
Brugia malayi 6-phosphofructokinase 0.0111 0.0302 0.1749
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0034 0.0025
Brugia malayi ecdysteroid receptor 0.0061 0.0138 0.0792
Schistosoma mansoni ap endonuclease 0.0076 0.0186 0.0185
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0133 0.0372 0.0364
Brugia malayi RNA, U transporter 1 0.0081 0.0204 0.1177
Schistosoma mansoni hypothetical protein 0.0086 0.0221 0.0219
Mycobacterium ulcerans hypothetical protein 0.0039 0.0067 0.0059
Brugia malayi hypothetical protein 0.0032 0.0045 0.0253
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0039 0.0286
Echinococcus granulosus microtubule associated protein 2 0.2027 0.6518 0.6515
Leishmania major cathepsin L-like protease 0.0062 0.0141 0.0346
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0121 0.0333 0.0869
Trichomonas vaginalis hypothetical protein 0.0021 0.0009 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0172 0.099
Loa Loa (eye worm) hypothetical protein 0.005 0.0103 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0138 0.0129
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0067 0.0176
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0133 0.0372 0.0364
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0016 0.0093
Trichomonas vaginalis sphingosine kinase, putative 0.0121 0.0333 0.1933
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0186 0.0184
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0031 0.0216
Mycobacterium ulcerans hypothetical protein 0.0072 0.0176 0.0167
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0133 0.0372 0.0371
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0302 0.1756
Brugia malayi mbt repeat family protein 0.005 0.0103 0.0592
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0176 0.0167
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0302 0.079
Schistosoma mansoni coup transcription factor 0.0061 0.0138 0.0136
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0172 0.1562
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0168 0.0488 0.1274
Schistosoma mansoni myst-related protein 0.0024 0.002 0.0018
Brugia malayi diacylglycerol kinase 0.0121 0.0333 0.1926
Leishmania major phosphoglycerate kinase C, glycosomal 0.0342 0.1052 0.2732
Schistosoma mansoni hypothetical protein 0.0042 0.0076 0.0074
Giardia lamblia Phosphoglycerate kinase 0.0342 0.1052 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0034 0.0188
Loa Loa (eye worm) RecQ helicase 0.0067 0.016 0.0151
Schistosoma mansoni DNA polymerase IV / kappa 0.0039 0.0067 0.0066
Toxoplasma gondii ABC1 family protein 0.0072 0.0176 0.1603
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0265 0.0692
Echinococcus granulosus ceramide kinase 0.0121 0.0333 0.0324
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0172 0.0163
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0045 0.0349
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.054 0.3131
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0141 0.0368
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0342 0.1052 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0205 0.0607 0.1586
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0126 0.0117
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0121 0.0333 0.1933
Trichomonas vaginalis diacylglycerol kinase, putative 0.0121 0.0333 0.1933
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1198 0.3828 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.0514 0.0506
Echinococcus granulosus bloom syndrome protein 0.0067 0.016 0.0151
Echinococcus multilocularis dna polymerase kappa 0.0179 0.0522 0.0513
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0176 0.046
Schistosoma mansoni cpg binding protein 0.0187 0.0547 0.0546
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0084 0.0083
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0302 0.0294
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0027 0.0025
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0141 0.0132
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0045 0.0118
Brugia malayi latrophilin 2 splice variant baaae 0.0375 0.1159 0.6725
Echinococcus granulosus geminin 0.0339 0.1042 0.1034
Brugia malayi tailless protein 0.0029 0.0034 0.0188
Echinococcus multilocularis neuropeptide s receptor 0.0931 0.2961 0.2955
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0139 0.0391 0.0383
Schistosoma mansoni apoferritin-2 0.0026 0.0027 0.0025
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0009 0.0023
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0166 0.0479 0.0471
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0172 0.099
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Mycobacterium tuberculosis Diacylglycerol kinase 0.0121 0.0333 0.0324
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1198 0.3828 1
Brugia malayi hypothetical protein 0.0029 0.0034 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0067 0.0176
Schistosoma mansoni nuclear receptor 0.0029 0.0034 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0125 0.0348 0.2014
Echinococcus granulosus dna polymerase kappa 0.0179 0.0522 0.0513
Onchocerca volvulus 0.0021 0.0009 0.01
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0138 0.0129
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0126 0.0349 0.0912
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0045 0.0118
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0186 0.1577
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0463 0.1443 0.1435
Onchocerca volvulus Huntingtin homolog 0.0239 0.0718 0.9736
Echinococcus multilocularis phosphoglycerate kinase 1 0.0342 0.1052 0.1044
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0091 0.052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Onchocerca volvulus 0.0071 0.0172 0.2315
Leishmania major sphingosine kinase A, B, putative 0.0121 0.0333 0.0848
Echinococcus granulosus importin subunit beta 1 0.0028 0.0033 0.0025
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0322
Brugia malayi CXXC zinc finger family protein 0.0173 0.0503 0.2915
Schistosoma mansoni nuclear receptor 0.0029 0.0034 0.0032
Onchocerca volvulus 0.0029 0.0034 0.044
Echinococcus multilocularis endoplasmin 0.0026 0.0024 0.0015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0125 0.0348 0.0347
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0045 0.0118
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0186 0.1699
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0045 0.0253
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0039 0.0284
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0121 0.0333 0.1933
Brugia malayi Bromodomain containing protein 0.0164 0.0475 0.275
Plasmodium vivax SET domain protein, putative 0.0034 0.0052 0.0415
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0567 0.1781 0.4639
Schistosoma mansoni hypothetical protein 0.0174 0.0505 0.0503
Schistosoma mansoni lamin 0.0026 0.0026 0.0024
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0302 0.0301
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0039 0.003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0163 0.0155
Brugia malayi Kelch motif family protein 0.0057 0.0127 0.0733
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0141 0.014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0044 0.0114
Loa Loa (eye worm) hypothetical protein 0.0342 0.1052 0.1044
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0091
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0067 0.0176
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0009 0.0003
Trichomonas vaginalis helicase, putative 0.0039 0.0068 0.0397
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0138 0.0792
Loa Loa (eye worm) hypothetical protein 0.0191 0.056 0.0551
Loa Loa (eye worm) hypothetical protein 0.0158 0.0452 0.0444
Echinococcus granulosus lamin 0.0026 0.0026 0.0017
Schistosoma mansoni hypothetical protein 0.0339 0.1042 0.1041
Mycobacterium ulcerans phosphoglycerate kinase 0.0342 0.1052 0.1044
Brugia malayi phosphofructokinase 0.0111 0.0302 0.1749
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0045 0.0043
Echinococcus multilocularis dnaJ subfamily B 0.2467 0.7944 0.7943
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0052 0.0051
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0027 0.0025
Echinococcus granulosus heat shock protein 90 0.0026 0.0024 0.0015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0176 0.0167
Loa Loa (eye worm) hypothetical protein 0.0549 0.1722 0.1715
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0394 0.2283
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0138 0.1851
Trypanosoma brucei hypothetical protein, conserved 0.0121 0.0333 0.0869
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0095
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0302 0.1756
Echinococcus multilocularis expressed conserved protein 0.0179 0.0522 0.0514
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0737 0.4281
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0302 0.2814
Brugia malayi heat shock protein 90 0.0032 0.0045 0.0254
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0126 0.0722
Plasmodium falciparum importin beta, putative 0.0028 0.0033 0.0272
Loa Loa (eye worm) acetyltransferase 0.0153 0.0438 0.043
Schistosoma mansoni endoplasmin 0.0032 0.0045 0.0044
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0302 0.079
Echinococcus multilocularis alkaline phosphatase 0.0166 0.0479 0.0471
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0031 0.0023
Trichomonas vaginalis DNA helicase recq, putative 0.0067 0.016 0.0928
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0176 0.0167
Schistosoma mansoni hypothetical protein 0.0079 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0239 0.0718 0.071
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0186 0.1081
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0176 0.0167
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0034 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Trypanosoma cruzi diacylglycerol kinase, putative 0.0121 0.0333 0.0869
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0103 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0138 0.0129
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0103 0.0102
Onchocerca volvulus 0.0121 0.0333 0.4504
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0052 0.0051
Onchocerca volvulus 0.0173 0.0503 0.6816
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0058 0.0129
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0138 0.0136
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0172 0.0163
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0091 0.0082
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0141 0.0132
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus granulosus heat shock protein 90 0.0032 0.0045 0.0036
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0009 0.0037
Echinococcus granulosus phosphoglycerate kinase 1 0.0342 0.1052 0.1044
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0141 0.0368
Schistosoma mansoni diacylglycerol kinase theta 0.0121 0.0333 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0168 0.0488 0.1274
Leishmania major hypothetical protein, conserved 0.0031 0.0041 0.0084
Schistosoma mansoni diacylglycerol kinase theta 0.0121 0.0333 0.0331
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0138 0.1851
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0045 0.0347
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0091 0.0082
Mycobacterium ulcerans hypothetical protein 0.0071 0.0172 0.0163
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0176 0.1603
Schistosoma mansoni bromodomain containing protein 0.0022 0.0013 0.0011
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0052 0.0043
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0049 0.004
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0024
Schistosoma mansoni hypothetical protein 0.0121 0.0333 0.0331
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0024 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0055 0.0118 0.011
Schistosoma mansoni myst-related protein 0.0024 0.002 0.0018
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0034 0.0025
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0044 0.0084 0.0076
Schistosoma mansoni DNA helicase recq5 0.0028 0.0031 0.003
Trypanosoma brucei unspecified product 0.0087 0.0222 0.0579
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Loa Loa (eye worm) CXXC zinc finger family protein 0.0173 0.0503 0.0495
Plasmodium falciparum zinc finger protein, putative 0.0024 0.002 0.0142
Echinococcus granulosus tumor protein p63 0.0328 0.1005 0.0997
Onchocerca volvulus 0.0026 0.0026 0.0328
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0368 0.1137 0.1135
Plasmodium vivax diacylglycerol kinase, putative 0.0121 0.0333 0.3105
Schistosoma mansoni importin beta-1 0.0028 0.0033 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0273 0.0825 0.0817
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0035
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0121 0.0333 0.3105
Loa Loa (eye worm) DR-78 0.0029 0.0034 0.0025
Leishmania major DNA polymerase kappa, putative 0.0039 0.0067 0.0153
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0121 0.0333 0.0324
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0009 0.0007
Echinococcus multilocularis heat shock protein 90 0.0032 0.0045 0.0036
Echinococcus multilocularis integrin alpha ps 0.0083 0.021 0.0201
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0098 0.0857
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0138 0.0792
Plasmodium vivax diacylglycerol kinase, putative 0.0121 0.0333 0.3105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0176 0.0175
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0027 0.0018
Loa Loa (eye worm) endoplasmin 0.0032 0.0045 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0067 0.0176
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0186 0.0177
Brugia malayi steroid hormone receptor 0.0061 0.0138 0.0792
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0009 0.0043
Schistosoma mansoni integrin alpha-ps 0.0083 0.021 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0299
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0342 0.1052 0.6111
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0138 0.0129
Leishmania major cathepsin L-like protease 0.0062 0.0141 0.0346
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0138 0.0129
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0113 0.1003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0138 0.0792
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0342 0.1052 1
Plasmodium falciparum heat shock protein 90 0.0032 0.0045 0.0385
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0186 0.173
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.0522 0.0513
Onchocerca volvulus 0.0245 0.0737 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0138 0.0129
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0034 0.0025
Echinococcus granulosus neuropeptide s receptor 0.0931 0.2961 0.2955
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0138 0.0129
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0057 0.0127 0.0119
Trypanosoma brucei phosphoglycerate kinase, putative 0.0126 0.0349 0.0912
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0044 0.0246
Loa Loa (eye worm) bromodomain containing protein 0.0039 0.0068 0.0059
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0113 0.0738
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0045 0.0036
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0024 0.0139
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Echinococcus granulosus GPCR family 2 0.0174 0.0505 0.0496
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.0522 0.1363
Loa Loa (eye worm) hypothetical protein 0.014 0.0394 0.0386
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0015
Brugia malayi polk-prov protein 0.0092 0.0241 0.1392
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0176 0.0167
Echinococcus granulosus Niemann Pick C1 protein 0.0273 0.0825 0.0817
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0349 0.0891
Plasmodium vivax DNA repair protein REV1, putative 0.0039 0.0067 0.0561
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0044 0.037
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0302 0.0294
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0174 0.0505 0.2924
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0098 0.0089
Trypanosoma cruzi ISWI complex protein 0.0031 0.0041 0.0107
Loa Loa (eye worm) hypothetical protein 0.0071 0.0172 0.0163
Entamoeba histolytica hypothetical protein 0.0144 0.0408 0.04
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.0408 0.04
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0059 0.0133 0.1225
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0009 0.0043
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0438 0.2539
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.002 0.0054
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0049 0.0128
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0141 0.0368
Echinococcus multilocularis dna polymerase eta 0.0177 0.0514 0.0506
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0105
Echinococcus granulosus intestinal type alkaline phosphatase 0.0166 0.0479 0.0471
Schistosoma mansoni sphingoid long chain base kinase 0.31 1 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Trypanosoma brucei Sphingosine kinase 0.0121 0.0333 0.0869
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0009 0.0023
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0121 0.0333 0.0324
Schistosoma mansoni ferritin light chain 0.0026 0.0027 0.0025
Echinococcus granulosus expressed protein 0.0026 0.0027 0.0018
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0125 0.0348 0.034
Loa Loa (eye worm) beta-lactamase 0.0072 0.0176 0.0167
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0121 0.0333 0.0324
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0045 0.0349
Loa Loa (eye worm) hypothetical protein 0.0121 0.0333 0.0324
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0045 0.0036
Schistosoma mansoni heat shock protein 0.0032 0.0045 0.0044
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0186 0.0464
Trichomonas vaginalis diacylglycerol kinase, putative 0.0121 0.0333 0.1933
Chlamydia trachomatis phosphoglycerate kinase 0.0342 0.1052 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0138 0.0129
Schistosoma mansoni hypothetical protein 0.004 0.007 0.0068
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0052 0.011 0.0974
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0093
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0098 0.057
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0176 0.1023
Echinococcus multilocularis expressed protein 0.0034 0.0052 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0176 0.1023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0179 0.0522 0.3029
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.002 0.0112
Trichomonas vaginalis rotamase, putative 0.0034 0.0052 0.0299
Loa Loa (eye worm) hypothetical protein 0.0145 0.0411 0.0403
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0009 0.0023
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0174 0.0505 0.0496
Mycobacterium ulcerans hypothetical protein 0.31 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.009
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.0522 0.0513
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0176 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0113 0.1036
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0039 0.0142
Mycobacterium ulcerans lipase LipD 0.0072 0.0176 0.0167
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.002 0.0052
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0044 0.0084 0.0076
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0045 0.0036
Brugia malayi nuclear receptor RXR 0.0029 0.0034 0.0188
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0302 0.0769
Loa Loa (eye worm) hypothetical protein 0.0086 0.0219 0.021
Onchocerca volvulus 0.0025 0.0022 0.0274
Brugia malayi MH2 domain containing protein 0.0242 0.0725 0.4208
Loa Loa (eye worm) hypothetical protein 0.0048 0.0097 0.0088
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0138 0.0136
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0191 0.056 0.0551
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0176 0.0167
Toxoplasma gondii diacylglycerol kinase, putative 0.0121 0.0333 0.3105
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0125 0.0348 0.034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0025 0.0024
Schistosoma mansoni lamin 0.0026 0.0026 0.0024
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0549 0.1722 1
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0335
Schistosoma mansoni hypothetical protein 0.0375 0.1159 0.1157
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Schistosoma mansoni ferritin 0.0026 0.0027 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0138 0.0792
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Brugia malayi hypothetical protein 0.0239 0.0718 0.4163
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0174 0.0505 0.0496
Schistosoma mansoni zinc finger protein 0.0053 0.0113 0.0111
Echinococcus multilocularis sterol regulatory element binding protein 0.0082 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0114
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0138 0.0129
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0024 0.0063
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0009 0.0023
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0342 0.1052 0.2749
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0138 0.0129
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0045 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0438 0.0437
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0302 0.1756
Onchocerca volvulus 0.0061 0.0138 0.1851
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Brugia malayi hypothetical protein 0.0024 0.002 0.0108
Loa Loa (eye worm) T-complex protein 1 0.0024 0.002 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0103 0.0095
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0103 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0138 0.0792
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0039
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus multilocularis expressed protein 0.0026 0.0027 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0138 0.0129
Loa Loa (eye worm) diacylglycerol kinase 2 0.0121 0.0333 0.0324
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.0408 0.0407
Echinococcus multilocularis bloom syndrome protein 0.0067 0.016 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0009 0.0043
Schistosoma mansoni heat shock protein 0.0032 0.0045 0.0044
Echinococcus granulosus intermediate filament protein 0.0026 0.0026 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0034 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0067 0.0176
Schistosoma mansoni alkaline phosphatase 0.0166 0.0479 0.0478
Schistosoma mansoni hypothetical protein 0.0144 0.0408 0.0407
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0172 0.099
Schistosoma mansoni hypothetical protein 0.0079 0.0197 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0138 0.0792
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0207 0.1199
Brugia malayi jmjC domain containing protein 0.0062 0.0141 0.0811
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0009 0.0054
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0186 0.1073
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0138 0.0129
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0034 0.0032
Echinococcus granulosus sterol regulatory element binding protein 0.0082 0.0207 0.0198
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0286
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0113 0.0105
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0009 0.0043
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0039 0.0286
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0024
Brugia malayi hypothetical protein 0.0057 0.0127 0.0733
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0114
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0302 0.0294
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0133 0.0372 0.0364
Trichomonas vaginalis ferritin, putative 0.0026 0.0027 0.0154
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0438 0.043
Schistosoma mansoni hypothetical protein 0.0339 0.1042 0.1041
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0176 0.1603
Schistosoma mansoni hypothetical protein 0.0079 0.0197 0.0196
Brugia malayi Phosphoglycerate kinase 0.0126 0.0349 0.202
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0036
Entamoeba histolytica recQ family helicase, putative 0.0036 0.0058 0.0049
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0052 0.0044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0034 0.0025
Leishmania major hypothetical protein, conserved 0.0121 0.0333 0.0848
Echinococcus multilocularis ferritin 0.0026 0.0027 0.0018
Loa Loa (eye worm) hypothetical protein 0.01 0.0266 0.0258
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0172 0.0427
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0105
Echinococcus granulosus Diacylglycerol kinase zeta 0.0121 0.0333 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0333 0.1933
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0349 0.0912
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0186 0.0177
Brugia malayi Latrophilin receptor protein 2 0.0174 0.0505 0.2924
Loa Loa (eye worm) hypothetical protein 0.0142 0.0403 0.0394
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.002 0.0112
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0121 0.0333 0.0869
Schistosoma mansoni hypothetical protein 0.0174 0.0505 0.0503
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.000000000037238 0.00000000021625
Brugia malayi Bloom's syndrome protein homolog 0.0067 0.016 0.092
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0039 0.003
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0121 0.0333 0.0869
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trichomonas vaginalis DNA helicase recq1, putative 0.0067 0.016 0.0928
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0172 0.1562
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.0522 0.1363
Mycobacterium tuberculosis Conserved hypothetical protein 0.0631 0.1988 0.1981
Brugia malayi beta-lactamase family protein 0.0072 0.0176 0.1015
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0024 0.0015
Echinococcus multilocularis lamin 0.0026 0.0026 0.0017
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.31 1 1
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0138 0.0136
Onchocerca volvulus 0.0021 0.0009 0.01
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Schistosoma mansoni ferritin 0.0026 0.0027 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Schistosoma mansoni phosphoglycerate kinase 0.0342 0.1052 0.1051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trichomonas vaginalis bmru protein, putative 0.0121 0.0333 0.1933
Echinococcus multilocularis neuropeptide receptor A26 0.0931 0.2961 0.2955
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0166 0.0479 0.0471
Trichomonas vaginalis heat shock protein, putative 0.002 0.0005 0.0029
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0045 0.0036
Echinococcus granulosus cpg binding protein 0.0187 0.0547 0.0539
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0031 0.0214
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0138 0.1851
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0138 0.0129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0176 0.0167
Brugia malayi nuclear hormone receptor 0.0061 0.0138 0.0792
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0322
Echinococcus multilocularis Diacylglycerol kinase theta 0.0121 0.0333 0.0324
Echinococcus multilocularis heat shock protein 0.0032 0.0045 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0034 0.0032
Brugia malayi hypothetical protein 0.0121 0.0333 0.1926
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0138 0.0792
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0067 0.0176
Mycobacterium tuberculosis Conserved protein 0.31 1 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0139 0.0391 0.1001
Echinococcus multilocularis ceramide kinase 0.0121 0.0333 0.0324
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0026 0.0017
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0044 0.0035
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0121 0.0333 0.0324
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0031 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Leishmania major mitochondrial DNA polymerase beta 0.1198 0.3828 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0091 0.0082
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0031 0.0023
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0176 0.046
Echinococcus granulosus Diacylglycerol kinase theta 0.0121 0.0333 0.0324
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0024 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.0348 0.034
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0061
Loa Loa (eye worm) glutaminase 0.0549 0.1722 0.1715
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0138 0.0136
Brugia malayi Endoplasmin precursor 0.0032 0.0045 0.0254
Loa Loa (eye worm) hypothetical protein 0.0071 0.0172 0.0163
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0068 0.0397
Brugia malayi nuclear receptor RXR 0.0032 0.0045 0.0253
Brugia malayi nuclear hormone receptor 0.0029 0.0034 0.0188
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Toxoplasma gondii histone lysine methyltransferase SET1 0.0338 0.1037 0.9849
Schistosoma mansoni zinc finger protein 0.0029 0.0034 0.0032
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0027 0.017
Trypanosoma brucei diacylglycerol kinase, putative 0.0121 0.0333 0.0869
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0172 0.0163
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0172 0.0163
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0172 0.0427
Brugia malayi conserved hypotetical protein 0.0029 0.0034 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0138 0.0792
Brugia malayi glutaminase DH11.1 0.0549 0.1722 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0176 0.0167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.009
Brugia malayi diacylglycerol kinase 0.0121 0.0333 0.1926
Brugia malayi Ceramide kinase 0.0121 0.0333 0.1926
Trichomonas vaginalis chaperonin, putative 0.0024 0.002 0.0119
Brugia malayi hypothetical protein 0.0144 0.0408 0.2363
Brugia malayi nuclear receptor NHR-67 0.0029 0.0034 0.0188
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0103 0.0102
Entamoeba histolytica hypothetical protein 0.0144 0.0408 0.04
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0103 0.0102
Brugia malayi CHE-14 protein 0.0082 0.0207 0.1192
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0033 0.0236
Echinococcus granulosus expressed protein 0.0034 0.0052 0.0043
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0091 0.0082
Schistosoma mansoni rotamase 0.0034 0.0052 0.005
Leishmania major cathepsin L-like protease 0.0062 0.0141 0.0346
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0044 0.0114
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0176 0.0167
Loa Loa (eye worm) hypothetical protein 0.0099 0.0263 0.0255
Echinococcus multilocularis protein patched 0.0082 0.0207 0.0198
Schistosoma mansoni hypothetical protein 0.2467 0.7944 0.7944
Plasmodium vivax endoplasmin, putative 0.0032 0.0045 0.0349
Trichomonas vaginalis bmru protein, putative 0.0121 0.0333 0.1933
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0045 0.0253
Giardia lamblia Grp94/Hsp90 0.0026 0.0024 0.0143
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0172 0.0163
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus granulosus expressed conserved protein 0.0179 0.0522 0.0514
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0068 0.0397
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0034 0.0188
Mycobacterium ulcerans beta-lactamase 0.0072 0.0176 0.0167
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0126 0.0117
Schistosoma mansoni microtubule-associated protein tau 0.2027 0.6518 0.6518
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Brugia malayi Pre-SET motif family protein 0.0216 0.0642 0.3723
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0055 0.012 0.0112
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0186 0.0486
Schistosoma mansoni ferritin 0.0026 0.0027 0.0025
Trypanosoma brucei phosphoglycerate kinase 0.0126 0.0349 0.0912
Leishmania major diacylglycerol kinase, putative 0.0121 0.0333 0.0848
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0025
Trichomonas vaginalis DNA helicase recq, putative 0.0036 0.0058 0.0336
Echinococcus multilocularis geminin 0.0339 0.1042 0.1034
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0071 0.0062
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0302 0.0294
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0186 0.1577
Schistosoma mansoni hypothetical protein 0.0079 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0121 0.0333 0.0324
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0141 0.0368
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Echinococcus granulosus Protein patched homolog 1 0.0082 0.0207 0.0198
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0126 0.0349 0.0912
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0138 0.0792
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0058 0.0151
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.0488 0.1274
Schistosoma mansoni zinc finger protein 0.0031 0.0041 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0174 0.0505 0.0496
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.002 0.0012
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0212 0.063 0.0622
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0567 0.1781 0.4651
Schistosoma mansoni apoferritin-2 0.0026 0.0027 0.0025
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0031 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0034 0.0025
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0071 0.063
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0052 0.0291
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0186 0.0486
Brugia malayi intermediate filament protein 0.0026 0.0026 0.014
Schistosoma mansoni hypothetical protein 0.0174 0.0505 0.0503
Brugia malayi isocitrate dehydrogenase 0.0032 0.0044 0.0246
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0176 0.1023
Trypanosoma cruzi hypothetical protein, conserved 0.0121 0.0333 0.0869
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0024 0.0146
Echinococcus multilocularis protein dispatched 1 0.0093 0.0244 0.0235
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0391 0.1022
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0302 0.0294
Echinococcus multilocularis integrin beta 2 0.028 0.085 0.0842
Toxoplasma gondii hypothetical protein 0.0193 0.0568 0.5358
Echinococcus multilocularis cpg binding protein 0.0187 0.0547 0.0539
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.002 0.0019
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0049 0.0105
Brugia malayi nuclear receptor NHR-88 0.0061 0.0138 0.0792
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0031 0.0023
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0138 0.0136
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0166 0.0479 0.0471
Loa Loa (eye worm) integrin beta-2 0.0378 0.1168 0.116
Loa Loa (eye worm) hypothetical protein 0.0092 0.0241 0.0232
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0186 0.0177
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0044 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0138 0.0792
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0302 0.2707
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0186 0.0177
Entamoeba histolytica hypothetical protein 0.0023 0.0016 0.0007
Leishmania major DNA damage repair protein, putative 0.0039 0.0067 0.0153
Plasmodium falciparum diacylglycerol kinase, putative 0.0121 0.0333 0.3131
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0121 0.0333 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0133 0.0372 0.0972
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0067 0.0176
Brugia malayi beta-lactamase 0.0072 0.0176 0.1015
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0138 0.0136
Treponema pallidum phosphoglycerate kinase 0.0342 0.1052 1
Brugia malayi Phosphoglycerate kinase 0.0342 0.1052 0.6107
Echinococcus granulosus heat shock protein 0.0032 0.0045 0.0036
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0045 0.0036
Echinococcus multilocularis snurportin 1 0.0304 0.0928 0.092
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0138 0.0129
Loa Loa (eye worm) hypothetical protein 0.0077 0.0192 0.0183
Entamoeba histolytica hypothetical protein, conserved 0.31 1 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0026 0.014
Echinococcus multilocularis tumor protein p63 0.0328 0.1005 0.0997
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0138 0.0129
Loa Loa (eye worm) ceramide kinase 0.0121 0.0333 0.0324
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0031 0.0023
Trypanosoma brucei unspecified product 0.0166 0.0479 0.125
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0034 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0138 0.0136
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0049 0.0128
Trichomonas vaginalis glutaminase, putative 0.0549 0.1722 1
Brugia malayi Eye-specific diacylglycerol kinase 0.0121 0.0333 0.1926
Schistosoma mansoni bromodomain containing protein 0.0141 0.0398 0.0397
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0055 0.012 0.0119
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0172 0.0163
Echinococcus multilocularis GPCR, family 2 0.0174 0.0505 0.0496
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Brugia malayi ImpB/MucB/SamB family protein 0.0177 0.0514 0.2981
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0172 0.0163
Toxoplasma gondii exonuclease III APE 0.0076 0.0186 0.1699
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0044
Leishmania major DNA polymerase kappa, putative 0.0139 0.0391 0.1001
Onchocerca volvulus 0.0021 0.0009 0.01
Brugia malayi Diacylglycerol kinase protein 2 0.0121 0.0333 0.1926
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.0408 0.04
Trypanosoma cruzi diacylglycerol kinase, putative 0.0121 0.0333 0.0869
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Brugia malayi jmjC domain containing protein 0.0075 0.0186 0.107
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0176 0.0167
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0035
Schistosoma mansoni terminal deoxycytidyl transferase 0.0125 0.0348 0.0347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Entamoeba histolytica diacylglycerol kinase, putative 0.0121 0.0333 0.0324
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0045 0.0118
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0138 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0138 0.0792
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.0725 0.0717
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0024 0.0139
Echinococcus multilocularis heat shock protein 90 0.0026 0.0024 0.0015
Schistosoma mansoni ferritin 0.0026 0.0027 0.0025
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0138 0.0129
Onchocerca volvulus 0.0072 0.0176 0.2374
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0095
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.002 0.0031
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0039 0.0224
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0549 0.1722 0.1715
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.002 0.0012
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0133 0.0372 0.2154
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.002 0.0012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0133 0.0372 0.0364
Schistosoma mansoni hypothetical protein 0.0319 0.0977 0.0976
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0241 0.0629
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0052 0.0051
Echinococcus multilocularis integrin alpha ps 0.004 0.007 0.0061
Mycobacterium ulcerans hypothetical protein 0.0631 0.1988 0.1981
Schistosoma mansoni ran 0.0021 0.0009 0.0008
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0052 0.0043
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Loa Loa (eye worm) hypothetical protein 0.0032 0.0045 0.0036
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0034 0.0188
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0124 0.0323
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0265 0.0692
Brugia malayi F/Y-rich N-terminus family protein 0.0058 0.0129 0.074
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0009 0.0051
Echinococcus multilocularis musashi 0.0026 0.0026 0.0017
Schistosoma mansoni integrin alpha 0.0185 0.054 0.0539
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0024 0.0063
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0138 0.0136
Trichomonas vaginalis ran, putative 0.0021 0.0009 0.0052
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0009 0.0043
Trichomonas vaginalis endoplasmin, putative 0.002 0.0005 0.0029
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0138 0.0136
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0176 0.0167
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0172 0.0163
Loa Loa (eye worm) glutaminase 2 0.0549 0.1722 0.1715
Plasmodium vivax importin-beta 2, putative 0.0028 0.0033 0.0236
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0342 0.1052 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0009 0.0043
Leishmania major hypothetical protein, conserved 0.0121 0.0333 0.0848
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0186 0.0486
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0045 0.0262
Schistosoma mansoni sphingosine kinase A B 0.31 1 1
Echinococcus granulosus integrin alpha ps 0.0083 0.021 0.0201
Loa Loa (eye worm) hypothetical protein 0.0057 0.0127 0.0119
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Leishmania major diacylglycerol kinase-like protein 0.0121 0.0333 0.0848
Entamoeba histolytica hypothetical protein 0.0024 0.002 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0093
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0044 0.0042
Trypanosoma brucei phosphoglycerate kinase 0.0342 0.1052 0.2749
Trypanosoma brucei DNA polymerase eta, putative 0.0177 0.0514 0.1344
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0174 0.0505 0.0496
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0138 0.0129
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0034 0.0032
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0928 0.092
Entamoeba histolytica hypothetical protein 0.0144 0.0408 0.04
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.0865 0.0857
Leishmania major DNA polymerase eta, putative 0.0177 0.0514 0.1324
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0126 0.0349 0.0912
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0067 0.0561
Brugia malayi Importin beta-1 subunit 0.0028 0.0033 0.0186
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0138 0.0129
Echinococcus granulosus integrin alpha 3 0.0142 0.04 0.0392
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0129
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0409 0.0401
Echinococcus granulosus neuropeptide receptor A26 0.0931 0.2961 0.2955
Echinococcus granulosus dna polymerase eta 0.0177 0.0514 0.0506
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.002 0.0111
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0052 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0068 0.0397
Brugia malayi mbt repeat family protein 0.005 0.0103 0.0592
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0172 0.0163
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0133 0.0372 0.0972
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0342 0.1052 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0126 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0567 0.1781 0.4651
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0098 0.0256
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0342 0.1052 0.2749
Echinococcus multilocularis lamin dm0 0.0026 0.0026 0.0017
Schistosoma mansoni DNA polymerase eta 0.0177 0.0514 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Schistosoma mansoni cpg binding protein 0.0173 0.0503 0.0502
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0009 0.0023
Schistosoma mansoni alkaline phosphatase 0.0166 0.0479 0.0478
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0138 0.0792
Echinococcus multilocularis microtubule associated protein 2 0.2027 0.6518 0.6515
Brugia malayi 6-phosphofructokinase 0.0111 0.0302 0.1749
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0027 0.0018
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.0058 0.0151
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0302 0.0301
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.002 0.0019
Echinococcus granulosus integrin alpha ps 0.004 0.007 0.0061
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0172 0.0163
Trypanosoma brucei DNA polymerase IV, putative 0.0166 0.0479 0.125
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.002 0.0052
Echinococcus multilocularis integrin alpha ps 0.0083 0.021 0.0201
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0034 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.0041 0.0039
Echinococcus granulosus dnaJ subfamily B 0.2467 0.7944 0.7943
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0302 0.0294
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0121 0.0333 0.1933
Echinococcus granulosus alkaline phosphatase 0.0166 0.0479 0.0471
Brugia malayi nuclear receptor NHR-88 0.0029 0.0034 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Trypanosoma brucei unspecified product 0.0087 0.0222 0.0579
Schistosoma mansoni patched 1 0.0082 0.0207 0.0205
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0186 0.0177
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0044 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0138 0.0129
Loa Loa (eye worm) hypothetical protein 0.0072 0.0176 0.0167
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1198 0.3828 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0095
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0176 0.1023
Onchocerca volvulus 0.0026 0.0026 0.0328
Brugia malayi Niemann-Pick C1 protein precursor 0.0191 0.056 0.3245
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0134 0.0375 0.0366
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0172 0.0163
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0186 0.1081
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.002 0.0149
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0335
Echinococcus granulosus fetal alzheimer antigen falz 0.0055 0.012 0.0112
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0138 0.0129
Trypanosoma cruzi ISWI complex protein 0.0031 0.0041 0.0107
Entamoeba histolytica diacylglycerol kinase, putative 0.0121 0.0333 0.0324
Echinococcus granulosus snurportin 1 0.0304 0.0928 0.092
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0052 0.0415
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0034 0.0025
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0342 0.1052 0.6111
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0016 0.0042
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0176 0.0167
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0642 0.0634
Entamoeba histolytica diacylglycerol kinase, putative 0.0121 0.0333 0.0324
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0034 0.0188
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0002 0.0007
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0034 0.0188
Entamoeba histolytica phosphoglycerate kinase, putative 0.0342 0.1052 0.1044
Trypanosoma brucei heat shock protein, putative 0.0032 0.0045 0.0118
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.002 0.0144
Entamoeba histolytica diacylglycerol kinase, putative 0.0121 0.0333 0.0324
Schistosoma mansoni hypothetical protein 0.0174 0.0505 0.0503
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0121 0.0333 0.0331
Echinococcus multilocularis zinc finger protein 0.0053 0.0113 0.0104
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0186 0.0177
Brugia malayi beta-lactamase family protein 0.0072 0.0176 0.1015
Loa Loa (eye worm) hypothetical protein 0.0102 0.0272 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0009 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0302 0.1756
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0168 0.0488 0.1274
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0172 0.0163
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0033 0.0025
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0302 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0138 0.0792
Brugia malayi Integrin beta pat-3 precursor 0.0378 0.1168 0.6781
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0176 0.1015
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0134 0.0375 0.0366
Trichomonas vaginalis sphingosine kinase, putative 0.0121 0.0333 0.1933
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.002 0.0054
Onchocerca volvulus Huntingtin homolog 0.0239 0.0718 0.9736
Onchocerca volvulus 0.0072 0.0176 0.2374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0141 0.0368
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0024 0.0139
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0286
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0186 0.0184
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0082 0.0207 0.0198
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0105
Leishmania major hypothetical protein, conserved 0.0072 0.0176 0.0438
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0095
Onchocerca volvulus 0.005 0.0103 0.1384
Schistosoma mansoni ferritin light chain 0.0026 0.0027 0.0025
Plasmodium vivax phosphoglycerate kinase, putative 0.0342 0.1052 1
Leishmania major heat shock protein 83-1 0.0032 0.0045 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0138 0.0129
Echinococcus granulosus zinc finger protein 0.0053 0.0113 0.0104
Onchocerca volvulus 0.0034 0.0052 0.0688
Mycobacterium tuberculosis Conserved protein 0.0072 0.0176 0.0167
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0034 0.044
Trypanosoma cruzi DNA polymerase eta, putative 0.009 0.0234 0.061
Giardia lamblia DNA damage repair protein 0.0039 0.0067 0.0559
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0522 0.1363
Echinococcus multilocularis integrin alpha 3 0.0142 0.04 0.0392
Brugia malayi PHD-finger family protein 0.0064 0.0147 0.0849
Echinococcus granulosus mixed lineage leukemia protein mll 0.0044 0.0084 0.0076
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0027 0.0018
Plasmodium falciparum phosphoglycerate kinase 0.0342 0.1052 1
Giardia lamblia DINP protein human, muc B family 0.0139 0.0391 0.3662
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0224
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0212 0.063 0.0622
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0121 0.0333 0.0324
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0091 0.0082
Echinococcus multilocularis Niemann Pick C1 protein 0.0191 0.056 0.0551
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0031 0.0216
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0039 0.0286
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0186 0.1697
Brugia malayi Pre-SET motif family protein 0.0034 0.0052 0.0294
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0121 0.0333 0.3105
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0045 0.0118
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.002 0.0119
Trypanosoma cruzi Sphingosine kinase 0.0121 0.0333 0.0869
Schistosoma mansoni hypothetical protein 0.0304 0.0928 0.0927
Brugia malayi hypothetical protein 0.0029 0.0034 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0068 0.0397
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.002 0.0108
Schistosoma mansoni integrin alpha-ps 0.0043 0.0081 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0163 0.0162
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0033 0.0087
Entamoeba histolytica deoxycytidyl transferase, putative 0.0125 0.0348 0.034
Onchocerca volvulus 0.0048 0.0097 0.1296
Leishmania major importin beta-1 subunit, putative 0.0023 0.0016 0.0019
Brugia malayi hypothetical protein 0.0032 0.0045 0.0253
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.0239 0.0718 0.071
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0186 0.0177
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0071 0.0593

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 16 uM Displacement of biotinylated fibrinogen from human glycoprotein 2b/3a receptor after 2 hrs by chemiluminescence assay ChEMBL. 23644213
Ki (binding) > 100 uM Inhibition of trypsin (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213
Ki (binding) > 100 uM Inhibition of thrombin (unknown origin) using S-2238 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213
Ki (binding) > 100 uM Inhibition of F10a (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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