Detailed information for compound 188431

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 301.706 | Formula: C11H14ClN4O4-
  • H donors: 5 H acceptors: 6 LogP: -0.39 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1[C@@H](O)[C@H](CN1c1c[nH]c2c1ncnc2O)O.[Cl-]
  • InChi: 1S/C11H14N4O4.ClH/c16-3-6-10(18)7(17)2-15(6)5-1-12-9-8(5)13-4-14-11(9)19;/h1,4,6-7,10,12,16-18H,2-3H2,(H,13,14,19);1H/p-1/t6-,7?,10+;/m1./s1
  • InChiKey: RSLOJRMKIOGNMF-CVZVNVELSA-M  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase pr2 0.0042 0.0035 0.0035
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0013 0.0001 0.0001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0042 0.0035 0.0035
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0264 0.0303 1
Trichomonas vaginalis protein tyrosine kinase, putative 0.0042 0.0035 0.1129
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0102 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0043 0.0043
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0129 0.014 0.0366
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0032 0.0023 0.0735
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0041 0.1331
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0039 0.0039
Entamoeba histolytica cysteine surface protein, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) RNA binding protein 0.0125 0.0135 0.0135
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0044 0.0037 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0135 0.0134
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Brugia malayi hypothetical protein 0.0024 0.0014 0.0013
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0135 0.0135
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0032 0.0023 0.0395
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0042 0.0035 0.0035
Brugia malayi Furin-like cysteine rich region family protein 0.0274 0.0314 0.0313
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0154 0.017 0.0169
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0037 0.0029 0.1653
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0797
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis FL cytokine receptor 0.0042 0.0035 0.0035
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0041 0.004
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Trypanosoma cruzi aurora B kinase, putative 0.0089 0.0091 1
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0056 0.0055
Brugia malayi ephrin receptor 1 precursor 0.0042 0.0035 0.0034
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0039 0.4185
Giardia lamblia Kinase, CMGC MAPK 0.0047 0.0041 0.1331
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0102 0.0102
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0029 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni serine/threonine RGC 0.0042 0.0035 0.0034
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0008 0.0005
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0122 0.0131 0.0131
Echinococcus multilocularis geminin 0.0178 0.0199 0.0199
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.1556
Schistosoma mansoni hypothetical protein 0.0042 0.0035 0.0034
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Brugia malayi serine/threonine protein kinase 6 0.0089 0.0091 0.0091
Loa Loa (eye worm) AUR protein kinase 0.0089 0.0091 0.0091
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0031 0.003
Mycobacterium ulcerans hypothetical protein 0.0037 0.0029 0.0539
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0025 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Brugia malayi Guanylyl cyclase protein 23 0.0042 0.0035 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.1556
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0015 0.0917
Trypanosoma brucei ISWI complex protein 0.0014 0.0001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis Immunoglobulin 0.0024 0.0014 0.0014
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0047 0.0041 0.4437
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0023 0.245
Entamoeba histolytica tyrosin kinase, putative 0.0042 0.0035 0.1129
Onchocerca volvulus 0.0042 0.0035 0.2018
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0015 0.0192
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3066 0.367 1
Brugia malayi hypothetical protein 0.0042 0.0035 0.0034
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0029 0.0028
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Entamoeba histolytica tyrosin kinase, putative 0.0042 0.0035 0.1129
Onchocerca volvulus 0.0042 0.0035 0.2018
Schistosoma mansoni smad 0.0015 0.0003 0.0002
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0042 0.0035 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0089 0.0091 0.3
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0023 0.0046
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus defective proboscis extension response 0.0024 0.0014 0.0014
Loa Loa (eye worm) protein kinase domain-containing protein 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0097 0.0102 0.0101
Loa Loa (eye worm) MH2 domain-containing protein 0.0216 0.0244 0.0244
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0029 0.0029
Schistosoma mansoni Smad4 0.0015 0.0003 0.0002
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0042 0.0035 0.1129
Echinococcus granulosus kinase suppressor of Ras 1 0.0042 0.0035 0.0035
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0043 0.0043
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Onchocerca volvulus 0.0042 0.0035 0.2018
Brugia malayi Tyrosine-protein kinase abl-1 0.0042 0.0035 0.0034
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0042 0.0035 0.1129
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0026 0.0016 0.0016
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0042 0.0035 0.0035
Entamoeba histolytica receptor protein kinase, putative 0.0042 0.0035 0.1129
Brugia malayi MH2 domain containing protein 0.0216 0.0244 0.0244
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Mycobacterium tuberculosis Conserved protein 0.0037 0.0029 0.0062
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.8332 1 1
Brugia malayi Bromodomain containing protein 0.0073 0.0073 0.0072
Mycobacterium ulcerans replicative DNA helicase DnaB 0.035 0.0405 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0047 0.0041 0.4437
Brugia malayi hypothetical protein 0.0042 0.0035 0.0034
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0011 0.0011
Echinococcus granulosus protein tyrosine phosphatase n9 0.0013 0.0001 0.0001
Plasmodium falciparum tyrosine kinase-like protein 0.0042 0.0035 0.3284
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0264 0.0303 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2358 0.282 0.282
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0013 0.0001 0.0001
Echinococcus granulosus raf serine:threonine protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0211 0.0238 0.0238
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0042 0.0035 0.0035
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0016 0.0004 0.0004
Entamoeba histolytica ankyrin repeat protein 0.0042 0.0035 0.1129
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0032 0.1021
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Leishmania major importin beta-1 subunit, putative 0.0023 0.0013 0.1333
Brugia malayi MH2 domain containing protein 0.0015 0.0003 0.0002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus intermediate filament protein 0.0026 0.0016 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0047 0.0041 0.4441
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Schistosoma mansoni ephrin receptor 0.0042 0.0035 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0023 0.2409
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Brugia malayi Protein kinase domain containing protein 0.2358 0.282 0.2819
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi MH2 domain containing protein 0.0015 0.0003 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis insulin receptor 0.0115 0.0123 0.0123
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0015 0.0024
Schistosoma mansoni lamin 0.0026 0.0016 0.0016
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Schistosoma mansoni tyrosine kinase 0.0124 0.0134 0.0133
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0035 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0015 0.0467
Plasmodium vivax tyrosine kinase-like protein, putative 0.0042 0.0035 0.3284
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0089 0.0091 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0098 0.0102 0.0721
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0039 0.1869
Treponema pallidum recombinase A 0.0098 0.0102 0.207
Onchocerca volvulus 0.0042 0.0035 0.2018
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0797
Schistosoma mansoni hypothetical protein 0.0178 0.0199 0.0198
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0008 0.0237
Schistosoma mansoni tyrosine kinase 0.0124 0.0134 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0042 0.0035 0.0035
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0042 0.0035 0.0035
Onchocerca volvulus 0.0037 0.0029 0.1653
Echinococcus multilocularis mitogen activated protein kinase 0.0047 0.0041 0.0041
Echinococcus granulosus dnaJ subfamily B 0.0397 0.0462 0.0462
Onchocerca volvulus 0.0042 0.0035 0.2018
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) TK/CSK protein kinase 0.0042 0.0035 0.0035
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0015 0.1571
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.002 0.0356
Loa Loa (eye worm) hypothetical protein 0.0122 0.0131 0.0131
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0032 0.1021
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0043 0.0036 0.1692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Schistosoma mansoni tyrosine kinase 0.0115 0.0123 0.0122
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Mycobacterium ulcerans catalase 0.0037 0.0029 0.0537
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0042 0.0035 0.0035
Echinococcus granulosus geminin 0.0178 0.0199 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0032 0.0023 0.0023
Echinococcus granulosus cpg binding protein 0.0031 0.0022 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0014
Leishmania major hypothetical protein, conserved 0.0014 0.0001 0.0058
Mycobacterium tuberculosis Conserved protein 0.0037 0.0029 0.0062
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0154 0.017 0.4082
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0047 0.0041 0.4437
Onchocerca volvulus 0.0025 0.0015 0.0835
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0161 0.0179 0.0178
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0013 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0192
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0042 0.0035 0.2018
Echinococcus multilocularis Smad4 0.0015 0.0003 0.0003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0129 0.014 0.1035
Echinococcus granulosus snurportin 1 0.0309 0.0356 0.0356
Leishmania major DNA polymerase eta, putative 0.0045 0.0039 0.4181
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni tyrosine protein kinase 0.0042 0.0035 0.0034
Leishmania major hypothetical protein, conserved 0.0025 0.0015 0.1565
Loa Loa (eye worm) apoptosis regulator protein 0.0161 0.0179 0.0179
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Schistosoma mansoni cpg binding protein 0.0028 0.0018 0.0018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0018 0.0018
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis lamin 0.0026 0.0016 0.0016
Brugia malayi hypothetical protein 0.0033 0.0024 0.0023
Mycobacterium ulcerans beta-lactamase 0.0037 0.0029 0.0539
Entamoeba histolytica hypothetical protein 0.0033 0.0024 0.0763
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0047 0.0041 0.0041
Echinococcus granulosus integrin linked protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis protein KINase family member (kin 25) 0.0042 0.0035 0.0035
Loa Loa (eye worm) AUR protein kinase 0.0089 0.0091 0.0091
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica ankyrin repeat protein 0.0042 0.0035 0.1129
Plasmodium falciparum protein kinase, putative 0.0043 0.0036 0.3446
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0013 0.1333
Brugia malayi serine/threonine kinase 12 0.0089 0.0091 0.0091
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0036 0.3914
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Brugia malayi C-terminal src kinase protein 1 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Echinococcus granulosus TGF beta signal transducer SmadC 0.0015 0.0003 0.0003
Brugia malayi bone morphogenetic protein type 1 receptor 0.0042 0.0035 0.0034
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0023 0.0022
Trichomonas vaginalis protein kinase atn1, putative 0.0042 0.0035 0.1129
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Brugia malayi Bromodomain containing protein 0.0038 0.0031 0.003
Trypanosoma cruzi ISWI complex protein 0.0014 0.0001 0.0058
Brugia malayi SH2 domain containing protein 0.0042 0.0035 0.0034
Echinococcus multilocularis raf serine:threonine protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Echinococcus granulosus GPCR family 2 0.0097 0.0102 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Brugia malayi hypothetical protein 0.0042 0.0035 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0029 0.0925
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.035 0.0405 0.3227
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0091 0.3
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0013
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0029 0.0925
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.8332 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0042 0.0035 0.2018
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0042 0.0035 0.0035
Echinococcus granulosus protein kinase 0.0042 0.0035 0.0035
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0041 0.4437
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0013 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0014 0.0013
Echinococcus multilocularis importin subunit beta 1 0.0029 0.002 0.002
Brugia malayi Tyrosine-protein kinase PR2 0.0042 0.0035 0.0034
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0161 0.0161
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0036 0.1174
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0041 0.1331
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0013 0.0001 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Plasmodium falciparum serine/threonine protein kinase, putative 0.0089 0.0091 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0135 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.035 0.0405 1
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Leishmania major hypothetical protein, conserved 0.0037 0.0029 0.3082
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0042 0.0035 0.2018
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0015 0.0192
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0036 0.3914
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0161 0.0161
Trypanosoma cruzi DNA repair protein, putative 0.003 0.0021 0.2211
Brugia malayi uridine phosphorylase family protein 0.0032 0.0023 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0041 0.1331
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Chlamydia trachomatis AMP nucleosidase 0.0032 0.0023 0.0395
Onchocerca volvulus 0.0042 0.0035 0.2018
Brugia malayi latrophilin 2 splice variant baaae 0.0211 0.0238 0.0237
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0055 0.3189
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0308 0.0355 0.0355
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0166 0.0184 0.0184
Schistosoma mansoni apoptosis regulator bax 0.0161 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0097 0.0102 0.0102
Toxoplasma gondii Purine nucleoside phosphorylase 0.0032 0.0023 0.0637
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0015 0.0917
Schistosoma mansoni microtubule-associated protein tau 0.067 0.079 0.079
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0308 0.0355 0.0355
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0056 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Echinococcus granulosus aurora kinase A 0.0089 0.0091 0.0091
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.8332 1 1
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosin kinase, putative 0.0042 0.0035 0.1129
Trypanosoma cruzi ISWI complex protein 0.0014 0.0001 0.0058
Schistosoma mansoni cpg binding protein 0.0031 0.0022 0.0022
Echinococcus granulosus dna polymerase eta 0.0045 0.0039 0.0039
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0041 0.4437
Loa Loa (eye worm) hypothetical protein 0.2357 0.2818 0.2818
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase Src64B 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0008 0.0007
Onchocerca volvulus 0.0042 0.0035 0.2018
Echinococcus multilocularis Immunoglobulin 0.0024 0.0014 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0039 0.1248
Echinococcus multilocularis tyrosine kinase 0.0042 0.0035 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Brugia malayi integrin-linked kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0035 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0035 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Toxoplasma gondii catalase 0.013 0.0141 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0015 0.1556
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Trypanosoma cruzi protein kinase, putative 0.0042 0.0035 0.3763
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0032 0.0023 0.0046
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0024 0.0014 0.0013
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0001 0.0001
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0032 0.0023 0.245
Schistosoma mansoni vesicular amine transporter 0.003 0.0021 0.0021
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0042 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0042 0.0035 0.0035
Echinococcus multilocularis zinc finger protein 0.0023 0.0012 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0043 0.0036 0.0036
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) TK/ACK protein kinase 0.0042 0.0035 0.0035
Onchocerca volvulus 0.0042 0.0035 0.2018
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Echinococcus granulosus tyrosine protein kinase pr2 0.0042 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0032 0.0023 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein tyrosine phosphatase 0.0013 0.0001 0.0001
Giardia lamblia UPL-1 0.0032 0.0023 0.0735
Schistosoma mansoni purine nucleoside phosphorylase 0.0154 0.017 0.0169
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Schistosoma mansoni hypothetical protein 0.0211 0.0238 0.0237
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Plasmodium falciparum importin beta, putative 0.0029 0.002 0.1449
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Echinococcus multilocularis smad 0.0015 0.0003 0.0003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0008 0.0007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0029 0.0539
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3336 0.3994 0.3994
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0042 0.0035 0.0035
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.8332 1 1
Echinococcus multilocularis c src tyrosine kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.0161 0.5294
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni hypothetical protein 0.0309 0.0356 0.0355
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0042 0.0035 0.0035
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0024 0.0024
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK/Met protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0178 0.0199 0.0198
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0042 0.0035 0.3767
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0016 0.0016
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0529 0.062 0.062
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0042 0.0035 0.0035
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0234 0.0266 0.0709
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0154 0.017 0.5594
Echinococcus granulosus tyrosine kinase 0.0042 0.0035 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Brugia malayi CXXC zinc finger family protein 0.0028 0.0018 0.0018
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0042 0.0035 0.1583
Loa Loa (eye worm) hypothetical protein 0.0064 0.0062 0.0062
Onchocerca volvulus 0.0042 0.0035 0.2018
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0023 0.0735
Mycobacterium leprae Conserved hypothetical protein 0.1031 0.1224 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0032 0.0023 0.2455
Echinococcus granulosus ephrin type A receptor 4 A 0.0042 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0033 0.0024 0.0763
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0035 0.0035
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0166 0.0184 0.0183
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0029 0.0062
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.0462 0.0462
Trypanosoma brucei protein tyrosine phosphatase 1 0.0013 0.0001 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Brugia malayi intermediate filament protein 0.0026 0.0016 0.0016
Onchocerca volvulus Tyrosine kinase homolog 0.0042 0.0035 0.2018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Echinococcus granulosus smad 0.0015 0.0003 0.0003
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0154 0.017 0.128
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.04
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0091 0.3
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Echinococcus multilocularis purine nucleoside phosphorylase 0.0122 0.0131 0.0131
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0042 0.0035 0.0035
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0161 0.0179 0.0179
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0013 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.0024 0.0023
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.2358 0.282 0.282
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0161 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0115 0.0123 0.0122
Leishmania major protein kinase, putative 0.0089 0.0091 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0042 0.0035 0.2018
Onchocerca volvulus 0.0137 0.0149 0.8782
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Schistosoma mansoni tyrosine kinase 0.0274 0.0314 0.0313
Loa Loa (eye worm) hypothetical protein 0.0161 0.0179 0.0179
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0003 0.0003
Echinococcus multilocularis kinase suppressor of Ras 1 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0047 0.0041 0.2069
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.002 0.063
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0014 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.002 0.2065
Mycobacterium ulcerans recombinase A 0.0098 0.0102 0.2383
Giardia lamblia Kinase 0.0042 0.0035 0.1129
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0091 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Loa Loa (eye worm) acetyltransferase 0.0147 0.0161 0.0161
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0042 0.0035 0.0035
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0029 0.3088
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Echinococcus granulosus activated cdc42 kinase 1 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0161 0.0179 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Echinococcus multilocularis integrin linked protein kinase 0.0042 0.0035 0.0035
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0047 0.0041 0.4437
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0035 0.0027 0.0027
Loa Loa (eye worm) TK/DDR protein kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Echinococcus granulosus methyl CpG binding domain protein 2 0.0015 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2358 0.282 0.282
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0029 0.0028
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus roundabout 2 0.0024 0.0014 0.0014
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.0024 0.0024
Schistosoma mansoni smad1 5 8 and 0.0015 0.0003 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Echinococcus multilocularis purine nucleoside phosphorylase 0.0122 0.0131 0.0131
Loa Loa (eye worm) transcription factor SMAD2 0.0216 0.0244 0.0244
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0102 0.0102
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.079
Brugia malayi Importin beta-1 subunit 0.0029 0.002 0.0019
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0042 0.0035 0.0034
Mycobacterium ulcerans lipase LipD 0.0037 0.0029 0.0539
Echinococcus granulosus tyrosine protein kinase Src42A 0.0042 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0035 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus methylthioadenosine phosphorylase 0.0032 0.0023 0.0023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0056 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trypanosoma cruzi DNA repair protein, putative 0.003 0.0021 0.2211
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0013 0.0001 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.002 0.063
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0135 0.0134
Schistosoma mansoni ephrin receptor 0.0042 0.0035 0.0034
Entamoeba histolytica protein kinase, putative 0.0089 0.0091 0.3
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis natriuretic peptide receptor 1 0.0042 0.0035 0.0035
Trichomonas vaginalis TK family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0089 0.0091 0.0091
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0007 0.0003
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0091 0.3
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0029 0.0062
Trypanosoma brucei unspecified product 0.0019 0.0008 0.0797
Loa Loa (eye worm) hypothetical protein 0.0035 0.0027 0.0027
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0023 0.0022
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0023 0.0022
Leishmania major hypothetical protein, conserved 0.0042 0.0035 0.3763
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Plasmodium vivax protein kinase, putative 0.0042 0.0035 0.3284
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0797
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Brugia malayi protein-tyrosine kinase 0.0042 0.0035 0.0034
Schistosoma mansoni smad1 5 8 and 0.0015 0.0003 0.0002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0016 0.0016
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.04
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni protein kinase 0.0043 0.0036 0.0036
Brugia malayi PHD-finger family protein 0.0028 0.0018 0.0017
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0008 0.0237
Echinococcus multilocularis receptor type guanylyl cyclase 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase shark 0.0042 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis uridine phosphorylase 1 0.0032 0.0023 0.0023
Toxoplasma gondii phosphorylase family protein 0.0032 0.0023 0.0637
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0008 0.0237
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0029 0.0925
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0035 0.0035
Echinococcus multilocularis mothers against decapentaplegic 5 0.0015 0.0003 0.0003
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0529 0.062 0.0619
Echinococcus granulosus activated cdc42 kinase 1 0.0042 0.0035 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.0091 0.3
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0015 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase 3 0.0047 0.0041 0.0041
Loa Loa (eye worm) TK/EPH protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0008 0.0017
Loa Loa (eye worm) TK/FAK protein kinase 0.0042 0.0035 0.0035
Onchocerca volvulus 0.0042 0.0035 0.2018
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0008 0.0008
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0529 0.062 0.0619
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0042 0.0035 0.0035
Schistosoma mansoni protein kinase 0.0089 0.0091 0.0091
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0089 0.0091 0.3
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0015 0.0467
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0035 0.1129
Leishmania major nucleoside phosphorylase-like protein 0.0032 0.0023 0.245
Trichomonas vaginalis STE family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0013 0.04
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0023 0.245
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0089 0.0091 0.3
Loa Loa (eye worm) AUR protein kinase 0.0089 0.0091 0.0091
Schistosoma mansoni tyrosine kinase 0.0166 0.0184 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Echinococcus multilocularis GPCR, family 2 0.0097 0.0102 0.0102
Trypanosoma cruzi protein kinase, putative 0.0042 0.0035 0.3763
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Echinococcus granulosus tyrosine protein kinase HCK 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK/RYK protein kinase 0.0042 0.0035 0.0035
Plasmodium vivax tyrosine kinase-like protein, putative 0.0042 0.0035 0.3284
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0015 0.0014
Echinococcus granulosus zinc finger protein 0.0023 0.0012 0.0012
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0042 0.0035 0.0035
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0032 0.0023 0.187
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0135 0.0135
Echinococcus granulosus histone lysine methyltransferase setb 0.0016 0.0004 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0161 0.0161
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK/ALK protein kinase 0.0042 0.0035 0.0035
Echinococcus granulosus receptor type guanylyl cyclase 0.0042 0.0035 0.0035
Entamoeba histolytica tyrosin kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0135 0.0134
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0015 0.0192
Loa Loa (eye worm) SRC-1 0.0042 0.0035 0.0035
Mycobacterium leprae probable uridine phosphorylase 0.0032 0.0023 0.0067
Schistosoma mansoni purine nucleoside phosphorylase 0.0154 0.017 0.0169
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Giardia lamblia Kinase, NEK 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0024 0.0014 0.0013
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0035 0.0035
Plasmodium falciparum protein kinase, putative 0.0042 0.0035 0.3284
Brugia malayi Smad1 0.0015 0.0003 0.0002
Schistosoma mansoni protein kinase 0.0043 0.0036 0.0036
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0309 0.0356 0.0356
Onchocerca volvulus 0.0026 0.0016 0.0911
Mycobacterium leprae Probable lipase LipE 0.0037 0.0029 0.0114
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0042 0.0035 0.0035
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Echinococcus granulosus insulin receptor 0.0115 0.0123 0.0123
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Brugia malayi SRC-1 0.0042 0.0035 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Brugia malayi RNA, U transporter 1 0.0082 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) TK/ABL protein kinase 0.0042 0.0035 0.0035
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0031 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0042 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0035 0.0034
Echinococcus multilocularis hypothetical protein 0.0013 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0035 0.0035
Echinococcus granulosus protein tyrosine kinase 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Echinococcus granulosus tar DNA binding protein 0.0125 0.0135 0.0135
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0011 0.0011
Echinococcus multilocularis protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni uridine phosphorylase 0.0032 0.0023 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0001 0.0001
Echinococcus granulosus importin subunit beta 1 0.0029 0.002 0.002
Plasmodium falciparum tyrosine kinase-like protein 0.0042 0.0035 0.3284
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0029 0.0062
Echinococcus multilocularis activated cdc42 kinase 1 0.0042 0.0035 0.0035
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0033 0.0024 0.0763
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis 0.0072 0.0072 0.0072
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0154 0.017 0.0446
Echinococcus multilocularis musashi 0.0026 0.0016 0.0016
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0033 0.0024 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0039 0.1869
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.04
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.067 0.079 0.079
Echinococcus granulosus twitchin 0.0025 0.0015 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Brugia malayi Calcitonin receptor-like protein seb-1 0.0308 0.0355 0.0355
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0029 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Brugia malayi beta-lactamase family protein 0.0037 0.0029 0.0028
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0042 0.0035 0.0034
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Toxoplasma gondii protein kinase 0.0042 0.0035 0.1583
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0039 0.1248
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0008 0.0008
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0008 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni hypothetical protein 0.0161 0.0179 0.0178
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.0024 0.0024
Leishmania major methylthioadenosine phosphorylase, putative 0.0032 0.0023 0.245
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0001 0.0001
Echinococcus multilocularis roundabout 2 0.0024 0.0014 0.0014
Echinococcus granulosus activin receptor type 0.0043 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0015 0.1565
Echinococcus multilocularis tyrosine protein kinase HCK 0.0042 0.0035 0.0035
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0032 0.0023 0.245
Loa Loa (eye worm) TK/EGFR protein kinase 0.0274 0.0314 0.0314
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0016
Loa Loa (eye worm) TK/INSR protein kinase 0.0115 0.0123 0.0123
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0015 0.0917
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trichomonas vaginalis esterase, putative 0.0037 0.0029 0.0925
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0043 0.0043
Schistosoma mansoni protein kinase 0.0043 0.0036 0.0036
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0001 0.0001
Echinococcus granulosus lamin dm0 0.0026 0.0016 0.0016
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0036 0.3918
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0035 0.0035
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0135 0.0134
Echinococcus multilocularis snurportin 1 0.0309 0.0356 0.0356
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase Lyn 0.0043 0.0036 0.0036
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Toxoplasma gondii phosphorylase family protein 0.0032 0.0023 0.0637
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0008 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0264 0.0303 1
Echinococcus multilocularis protein tyrosine kinase 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase Srms 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Echinococcus granulosus mitogen activated protein kinase 0.0047 0.0041 0.0041
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0029 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) Smad1 0.0015 0.0003 0.0003
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0097 0.0102 0.0101
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase, putative 0.0089 0.0091 0.3
Plasmodium vivax importin-beta 2, putative 0.0029 0.002 0.1449
Echinococcus granulosus tyrosine kinase 0.0042 0.0035 0.0035
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0039 0.4181
Toxoplasma gondii protein kinase domain-containing protein 0.0042 0.0035 0.1583
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine kinase 0.0042 0.0035 0.0035
Onchocerca volvulus 0.0026 0.0016 0.0911
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0008 0.0005
Giardia lamblia Aurora kinase 0.0089 0.0091 0.3
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Brugia malayi SH2 domain containing protein 0.0042 0.0035 0.0034
Brugia malayi hypothetical protein 0.0137 0.0149 0.0148
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Treponema pallidum replicative DNA helicase (dnaB) 0.035 0.0405 1
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0032 0.0023 0.0395
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni hypothetical protein 0.0097 0.0102 0.0101
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Echinococcus multilocularis heat shock protein 70 0.0042 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0097 0.0102 0.0101
Schistosoma mansoni intermediate filament proteins 0.0026 0.0016 0.0016
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0028 0.0018 0.1032
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0016 0.0016
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0066 0.0064 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0041 0.1331
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0023 0.0735
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0015 0.0003 0.0002
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0154 0.017 0.5594
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0042 0.0035 0.0034
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) twinkle helicase 0.01 0.0105 0.0105
Echinococcus granulosus c src tyrosine kinase 0.0042 0.0035 0.0035
Brugia malayi beta-lactamase 0.0037 0.0029 0.0028
Schistosoma mansoni importin beta-1 0.0029 0.002 0.0019
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0024 0.0024
Brugia malayi RNA binding protein 0.0125 0.0135 0.0134
Echinococcus multilocularis protein kinase 0.0042 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Mycobacterium tuberculosis Hypothetical protein 0.0032 0.0023 0.0046
Treponema pallidum fructose-bisphosphate aldolase 0.0264 0.0303 0.7319
Entamoeba histolytica hypothetical protein 0.0033 0.0024 0.0763
Giardia lamblia Protein 21.1 0.0042 0.0035 0.1129
Schistosoma mansoni cell adhesion molecule 0.0024 0.0014 0.0013
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0161 0.0179 0.0178
Entamoeba histolytica protein kinase , putative 0.0089 0.0091 0.3
Echinococcus granulosus Immunoglobulin 0.0024 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0115 0.0123 0.0122
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis tyrosine kinase 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Mycobacterium tuberculosis Conserved protein 0.0037 0.0029 0.0062
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0039 0.3711
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0029 0.3082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0015 0.0467
Entamoeba histolytica hypothetical protein 0.0032 0.0023 0.0735
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Plasmodium falciparum protein kinase, putative 0.0042 0.0035 0.3284
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0529 0.062 0.062
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0035 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Schistosoma mansoni lamin 0.0026 0.0016 0.0016
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.002 0.2065
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0029 0.0539
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0023 0.0608
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0043 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2814 0.3367 0.9173
Echinococcus multilocularis neuroglian 0.0024 0.0014 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0043 0.0043
Toxoplasma gondii ABC1 family protein 0.0037 0.0029 0.1093
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0035 0.0035
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Brugia malayi serine/threonine-protein kinase 6 0.0089 0.0091 0.0091
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0102 0.0102
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0115 0.0123 0.0123
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0042 0.0035 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0192
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.0037 0.0029 0.0028
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0023 0.245
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0004 0.0003
Echinococcus granulosus purine nucleoside phosphorylase 0.0154 0.017 0.017
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0161 0.0179 0.0179
Giardia lamblia DINP protein human, muc B family 0.0019 0.0008 0.0237
Trypanosoma brucei uridine phosphorylase 0.0032 0.0023 0.2455
Echinococcus granulosus mothers against decapentaplegic 5 0.0015 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.2399 0.2868 0.2868
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0308 0.0355 0.0355
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis 0.0013 0.0001 0.0001
Mycobacterium ulcerans catalase KatE 0.013 0.0141 0.3354
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0042 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus mitogen activated protein kinase 3 0.0047 0.0041 0.0041
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0029 0.0062
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Giardia lamblia Fructose-bisphosphate aldolase 0.0264 0.0303 1
Echinococcus granulosus epidermal growth factor receptor 0.0166 0.0184 0.0184
Echinococcus granulosus natriuretic peptide receptor 1 0.0042 0.0035 0.0035
Echinococcus multilocularis activin receptor type 0.0043 0.0036 0.0036
Toxoplasma gondii aurora kinase 0.0089 0.0091 0.6077
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0043 0.0043
Schistosoma mansoni protein tyrosine kinase 0.0042 0.0035 0.0034
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) beta-lactamase 0.0037 0.0029 0.0029
Echinococcus multilocularis epidermal growth factor receptor 0.0274 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.2357 0.2818 0.2818
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0042 0.0035 0.0035
Leishmania major protein kinase, putative 0.0043 0.0036 0.3914
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus microtubule associated protein 2 0.067 0.079 0.079
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0154 0.017 1
Toxoplasma gondii STE kinase 0.0042 0.0035 0.1583
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus Smad4 0.0015 0.0003 0.0003
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0015 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Echinococcus granulosus lamin 0.0026 0.0016 0.0016
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis aurora kinase A 0.0089 0.0091 0.0091
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Giardia lamblia Kinase, NEK 0.0042 0.0035 0.1129
Echinococcus granulosus uridine phosphorylase 1 0.0032 0.0023 0.0023
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Trypanosoma brucei Flagellum attachment zone protein 20 0.0042 0.0035 0.3767
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0032 0.0023 0.0735
Loa Loa (eye worm) hypothetical protein 0.0037 0.0029 0.0029
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0002
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0042 0.0035 0.0034
Chlamydia trachomatis replicative DNA helicase 0.035 0.0405 1
Echinococcus granulosus epidermal growth factor receptor 0.0274 0.0314 0.0314
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0042 0.0035 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.079
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0129 0.014 0.3337
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0032 0.2898
Loa Loa (eye worm) hypothetical protein 0.0152 0.0168 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0029 0.3082
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0029 0.0925
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0013 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0015 0.1565
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0024 0.0014 0.0014
Schistosoma mansoni zinc finger protein 0.0014 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0043 0.0043
Plasmodium falciparum purine nucleoside phosphorylase 0.0032 0.0023 0.187
Mycobacterium ulcerans hypothetical protein 0.0025 0.0015 0.0192
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0013 0.0001 0.0001
Schistosoma mansoni nephrin 0.0024 0.0014 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0135 0.0134
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus multilocularis tyrosine protein kinase shark 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase 0.0042 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0032 0.0023 0.0735
Entamoeba histolytica serine/threonine kinase, putative 0.0042 0.0035 0.1129
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0152 0.0168 0.0167
Schistosoma mansoni hypothetical protein 0.0397 0.0462 0.0462
Trypanosoma brucei aurora B kinase 0.0089 0.0091 1
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0008 0.0017
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Brugia malayi MTAP 0.0032 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0042 0.0035 0.2018
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0001 0.0001
Echinococcus multilocularis cpg binding protein 0.0031 0.0022 0.0022
Echinococcus granulosus dna polymerase kappa 0.0019 0.0008 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Entamoeba histolytica hypothetical protein 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Loa Loa (eye worm) TK/ROR protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0029 0.0062
Echinococcus multilocularis transfer RNA-Thr 0.0042 0.0035 0.0035
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0115 0.0123 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Schistosoma mansoni cpg binding protein 0.0031 0.0022 0.0022
Leishmania major protein kinase, putative 0.0042 0.0035 0.3763
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trypanosoma brucei Pseudokinase, putative 0.0042 0.0035 0.3767
Echinococcus multilocularis tyrosine protein kinase Abl 0.0042 0.0035 0.0035
Loa Loa (eye worm) serine/threonine protein kinase 0.0042 0.0035 0.0035
Schistosoma mansoni smad1 5 8 and 0.0015 0.0003 0.0002
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0042 0.0035 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.079
Echinococcus multilocularis dna polymerase eta 0.0045 0.0039 0.0039
Schistosoma mansoni Replicative DNA helicase 0.035 0.0405 0.0404
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0042 0.0035 0.2018
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0042 0.0035 0.0034
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0102 0.0101
Schistosoma mansoni bromodomain containing protein 0.0062 0.006 0.0059
Brugia malayi Protein kinase domain containing protein 0.0042 0.0035 0.0034
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Onchocerca volvulus 0.0037 0.0029 0.1653
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Trypanosoma brucei protein kinase, putative 0.0047 0.0041 0.4441
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0029 0.2551
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0029 0.0062
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0529 0.062 0.062
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0023 0.0735
Echinococcus multilocularis epidermal growth factor receptor 0.0166 0.0184 0.0184
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0042 0.0035 0.0034
Onchocerca volvulus 0.0042 0.0035 0.2018
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0161 0.0179 0.0178
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0043 0.0036 0.0036
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0042 0.0035 0.1583
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0042 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase ABL1 0.0042 0.0035 0.0035
Schistosoma mansoni DNA polymerase eta 0.0045 0.0039 0.0038
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.003 0.0021 0.2217
Loa Loa (eye worm) hypothetical protein 0.0137 0.0149 0.0149
Brugia malayi Raf kinase 0.0042 0.0035 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0091 0.3
Schistosoma mansoni protein kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0042 0.0035 0.0035
Brugia malayi MAP kinase sur-1 0.0047 0.0041 0.004
Schistosoma mansoni zinc finger protein 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0089 0.0091 0.0091
Echinococcus multilocularis ephrin type A receptor 4 A 0.0042 0.0035 0.0035
Echinococcus granulosus neuroglian 0.0024 0.0014 0.0014
Trypanosoma brucei protein kinase, putative 0.0043 0.0036 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Echinococcus multilocularis purine nucleoside phosphorylase 0.0154 0.017 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0161 0.0179 0.0179
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0102 0.0102
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.079
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0035 0.0035
Loa Loa (eye worm) TK protein kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0035 0.1129
Brugia malayi Receptor family ligand binding region containing protein 0.0042 0.0035 0.0034
Brugia malayi TAR-binding protein 0.0125 0.0135 0.0134
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0015 0.0192
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica receptor protein kinase, putative 0.0042 0.0035 0.1129
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0042 0.0035 0.1129
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.8332 1 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0001 0.0001
Schistosoma mansoni uridine phosphorylase 0.0032 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0035 0.0034
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0042 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0124 0.0134 0.0133
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0042 0.0035 0.0035
Loa Loa (eye worm) uridine phosphorylase 0.0032 0.0023 0.0023
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0035
Entamoeba histolytica protein kinase, putative 0.0042 0.0035 0.1129
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0029 0.0925
Leishmania major DNA polymerase eta, putative 0.0032 0.0023 0.2409
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0008 0.079
Leishmania major DNA polymerase kappa, putative 0.0019 0.0008 0.079
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0797
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0035 0.1129
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0102 0.0102
Entamoeba histolytica tyrosine kinase, putative 0.0042 0.0035 0.1129
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0035 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0035 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0035 0.1129
Chlamydia trachomatis recombinase RecA 0.0098 0.0102 0.2383
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0015 0.0192

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 12700 nM Inhibition of human purine nucleoside phosphorylase; Initial rate. ChEMBL. 12852771
ND (binding) 0 Inhibition of human purine nucleoside phosphorylase; Slow onset inhibition - Not determined. ChEMBL. 12852771

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.