Detailed information for compound 2075637

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 460.427 | Formula: C18H19F3N4O5S
  • H donors: 1 H acceptors: 6 LogP: 1.68 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.CN(C(=O)c1ncn2c1CN(C)S(=O)(=O)c1c2cccc1)C1CC1
  • InChi: 1S/C16H18N4O3S.C2HF3O2/c1-18-9-13-15(16(21)19(2)11-7-8-11)17-10-20(13)12-5-3-4-6-14(12)24(18,22)23;3-2(4,5)1(6)7/h3-6,10-11H,7-9H2,1-2H3;(H,6,7)
  • InChiKey: OMYSEAODPOTNRW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis isocitrate dehydrogenase 0.0074 0.057 0.0543
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0074 0.057 0.0641
Echinococcus multilocularis peroxidasin 0.0606 0.6349 0.6339
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0278 0.041
Echinococcus multilocularis protein dispatched 1 0.0056 0.0373 0.0346
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0028 0.0127
Brugia malayi hypothetical protein 0.0118 0.105 0.1629
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0028 0.0127
Leishmania major alpha tubulin 0.0288 0.29 0.806
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0278 0.041
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0028 0.0127
Brugia malayi hypothetical protein 0.0028 0.0068 0.0077
Leishmania major alpha tubulin 0.0288 0.29 0.806
Trichomonas vaginalis tubulin alpha chain, putative 0.012 0.1068 0.2833
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0216 0.0413
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0045 0.0252 0.0515
Loa Loa (eye worm) hypothetical protein 0.0057 0.0382 0.0574
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Brugia malayi Tubulin beta chain 0.0092 0.0764 0.1178
Brugia malayi MH2 domain containing protein 0.0037 0.017 0.0238
Echinococcus multilocularis lamin 0.0122 0.1095 0.1069
Loa Loa (eye worm) CYP4Cod1 0.0064 0.046 0.0698
Onchocerca volvulus 0.0275 0.2754 0.4321
Echinococcus multilocularis Tubulin alpha 1 chain 0.0288 0.29 0.2879
Leishmania major alpha tubulin 0.0288 0.29 0.806
Brugia malayi Cytochrome P450 family protein 0.0024 0.0028 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0278 0.0296
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0066 0.0486 0.0738
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0278 0.0251
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0028 0.0127
Echinococcus granulosus tubulin gamma 1 chain 0.0212 0.2068 0.2414
Loa Loa (eye worm) blistered cuticle protein 3 0.0606 0.6349 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0068 0.0047
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0196 0.19 0.2971
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0717 0.0816
Trypanosoma cruzi zeta tubulin, putative 0.0092 0.0764 0.2066
Trypanosoma brucei beta tubulin 0.0352 0.3591 1
Echinococcus multilocularis neuropeptide receptor A26 0.0539 0.5621 0.5609
Toxoplasma gondii isocitrate dehydrogenase 0.0074 0.057 0.1521
Brugia malayi MH1 domain containing protein 0.0037 0.017 0.0238
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0389 0.0427
Loa Loa (eye worm) hypothetical protein 0.0059 0.0406 0.0612
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0127 0.0117
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0118 0.1051 0.2926
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0045 0.0252 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.0305
Echinococcus multilocularis tubulin alpha 1C chain 0.0288 0.29 0.2879
Echinococcus granulosus Niemann Pick C1 protein 0.0163 0.154 0.179
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0028 0.0127
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Trypanosoma brucei epsilon tubulin 0.0212 0.2068 0.5758
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0272 0.2718 0.4264
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0033 0.0091
Echinococcus granulosus beta tubulin 0.0352 0.3591 0.4218
Brugia malayi MH2 domain containing protein 0.0037 0.017 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0332 0.0743
Echinococcus multilocularis Tubulin beta 2C chain 0.0352 0.3591 0.3573
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0169 0.1596 0.4335
Loa Loa (eye worm) BEN-1 protein 0.0352 0.3591 0.5643
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0252 0.0368
Schistosoma mansoni hypothetical protein 0.0053 0.0341 0.037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0278 0.041
Leishmania major beta tubulin 0.0352 0.3591 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0332 0.0359
Echinococcus multilocularis dna polymerase kappa 0.0045 0.0252 0.0224
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0028 0.0127
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0278 0.041
Leishmania major alpha tubulin 0.0288 0.29 0.806
Loa Loa (eye worm) tubulin alpha chain 0.0288 0.29 0.4551
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0028 0.0127
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0118 0.1051 0.287
Toxoplasma gondii beta tubulin 0.0352 0.3591 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0118 0.1051 0.287
Echinococcus granulosus dna polymerase eta 0.0045 0.0252 0.0264
Trypanosoma brucei unspecified product 0.0045 0.0252 0.0701
Brugia malayi Blistered cuticle protein 3 0.0606 0.6349 1
Brugia malayi MH2 domain containing protein 0.0547 0.5714 0.8997
Brugia malayi Tubulin gamma chain 0.0212 0.2068 0.3236
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0074 0.057 0.1521
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0242 0.2391 0.3748
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0278 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.01 0.0085
Echinococcus granulosus mothers against decapentaplegic 5 0.0037 0.017 0.0167
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Loa Loa (eye worm) animal heme peroxidase 0.0606 0.6349 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0032 0.0182
Loa Loa (eye worm) cytochrome P450 0.0024 0.0028 0.0015
Trypanosoma cruzi tubulin gamma chain 0.0212 0.2068 0.5724
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0066 0.0486 0.6198
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0028 0.0127
Toxoplasma gondii alpha tubulin TUBA1 0.0288 0.29 0.806
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0278 0.041
Loa Loa (eye worm) Smad1 0.0037 0.017 0.0238
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0032 0.0182
Echinococcus granulosus tubulin subunit beta 0.0352 0.3591 0.4218
Echinococcus multilocularis Tubulin beta 2C chain 0.0352 0.3591 0.3573
Loa Loa (eye worm) hypothetical protein 0.0057 0.0382 0.0574
Schistosoma mansoni hypothetical protein 0.0047 0.0278 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0118 0.105 0.1629
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Echinococcus multilocularis geminin 0.0795 0.8406 0.8401
Echinococcus multilocularis neurogenic locus notch protein 0.0078 0.0615 0.0589
Echinococcus granulosus survival motor neuron protein 1 0.0275 0.2749 0.3221
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0103 0.0094
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0298 0.0319
Leishmania major alpha tubulin 0.0288 0.29 0.806
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0169 0.1596 0.2492
Onchocerca volvulus 0.0078 0.0615 0.0942
Schistosoma mansoni peroxidasin 0.0606 0.6349 0.7483
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0278 0.0296
Brugia malayi hypothetical protein 0.0606 0.6349 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0028 0.0127
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Loa Loa (eye worm) beta-tubulin 0.0352 0.3591 0.5643
Echinococcus multilocularis Niemann Pick C1 protein 0.0114 0.1007 0.0982
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Echinococcus granulosus tubulin alpha chain 0.0288 0.29 0.3399
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0028 0.0079
Trypanosoma cruzi tubulin delta chain 0.0092 0.0764 0.2066
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0278 0.041
Brugia malayi Animal haem peroxidase family protein 0.0606 0.6349 1
Echinococcus multilocularis peroxisome assembly protein 26 0.0288 0.29 0.2879
Schistosoma mansoni DNA polymerase eta 0.0045 0.0252 0.0264
Mycobacterium ulcerans cell division protein FtsZ 0.0092 0.0764 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0278 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.1051 0.121
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0074 0.057 0.0543
Trypanosoma brucei zeta tubulin, putative 0.0092 0.0764 0.2129
Echinococcus multilocularis tubulin alpha chain 0.0288 0.29 0.2879
Brugia malayi MAP kinase sur-1 0.0118 0.1051 0.163
Echinococcus multilocularis tubulin delta chain 0.0092 0.0764 0.0738
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0332 0.0924
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0074 0.057 0.0543
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0278 0.0296
Schistosoma mansoni survival motor neuron protein 0.0056 0.0373 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0278 0.041
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0092 0.0764 0.1972
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0028 0.0127
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Schistosoma mansoni hypothetical protein 0.006 0.0417 0.046
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.0378 0.0415
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0278 0.0296
Brugia malayi Calcium binding EGF domain containing protein 0.0078 0.0615 0.0942
Trichomonas vaginalis tubulin epsilon chain, putative 0.0092 0.0764 0.1972
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0074 0.057 0.1511
Schistosoma mansoni slit 0.0078 0.0615 0.0695
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.1051 0.2785
Brugia malayi Tubulin alpha-2 chain 0.0288 0.29 0.4551
Leishmania major beta tubulin 0.0352 0.3591 1
Onchocerca volvulus 0.0122 0.1095 0.1699
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0078 0.0615 0.0942
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Loa Loa (eye worm) isocitrate dehydrogenase 0.0074 0.057 0.0871
Echinococcus granulosus Tubulin beta 2C chain 0.0352 0.3591 0.4218
Plasmodium vivax tubulin epsilon chain, putative 0.0212 0.2068 0.5719
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0252 0.3122
Trypanosoma brucei alpha tubulin 0.0288 0.29 0.8075
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0077
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0531 0.6867
Trichomonas vaginalis tubulin gamma chain, putative 0.0352 0.3591 1
Plasmodium vivax tubulin beta chain, putative 0.0352 0.3591 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0252 0.0627
Trypanosoma brucei protein kinase, putative 0.0118 0.1051 0.2926
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0531 0.6867
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0066 0.0486 0.0459
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0028 0.0127
Echinococcus granulosus expressed conserved protein 0.0107 0.0932 0.107
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0419 0.0632
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Echinococcus granulosus tubulin beta 4A class IVa 0.0352 0.3591 0.4218
Loa Loa (eye worm) alpha-tubulin 0.0288 0.29 0.4551
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0278 0.041
Brugia malayi cytochrome P450 0.0024 0.0028 0.0015
Trichomonas vaginalis tubulin alpha chain, putative 0.0352 0.3591 1
Brugia malayi Pax transcription factor protein 2 0.0559 0.584 0.9196
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0764 0.1972
Brugia malayi Tubulin alpha chain 0.0092 0.0764 0.1178
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0089 0.0732 0.1966
Leishmania major beta tubulin 0.0352 0.3591 1
Schistosoma mansoni tubulin subunit delta 0.0092 0.0764 0.0871
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Loa Loa (eye worm) hypothetical protein 0.0275 0.2749 0.4313
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Brugia malayi beta-tubulin, identical 0.0352 0.3591 0.5643
Brugia malayi bZIP transcription factor family protein 0.0097 0.0824 0.1273
Loa Loa (eye worm) alpha-tubulin 0.0288 0.29 0.4551
Brugia malayi intermediate filament protein 0.0122 0.1095 0.1699
Echinococcus multilocularis mitogen activated protein kinase 0.0118 0.1051 0.1025
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0045 0.0252 0.3122
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0074 0.057 0.0543
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0032 0.0011
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0278 0.0251
Echinococcus multilocularis beta tubulin 0.0352 0.3591 0.3573
Onchocerca volvulus 0.0078 0.0615 0.0942
Trichomonas vaginalis tubulin epsilon chain, putative 0.0352 0.3591 1
Loa Loa (eye worm) BEN-1 protein 0.0352 0.3591 0.5643
Loa Loa (eye worm) animal heme peroxidase 0.0606 0.6349 1
Trypanosoma brucei beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Leishmania major delta tubulin, putative 0.0092 0.0764 0.2066
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0278 0.0296
Echinococcus granulosus dna polymerase kappa 0.0045 0.0252 0.0264
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.023 0.0334
Onchocerca volvulus 0.0035 0.0141 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0278 0.041
Brugia malayi hypothetical protein 0.0077 0.0597 0.0913
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0028 0.0127
Brugia malayi Tubulin alpha chain 0.0288 0.29 0.4551
Entamoeba histolytica hypothetical protein 0.0163 0.1539 0.4234
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0077
Treponema pallidum exodeoxyribonuclease (exoA) 0.0066 0.0486 0.6198
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0028 0.0127
Echinococcus granulosus Tubulin alpha 1 chain 0.0288 0.29 0.3399
Loa Loa (eye worm) tubulin alpha 2 0.0196 0.19 0.2971
Brugia malayi Cytochrome P450 family protein 0.0064 0.046 0.0698
Trypanosoma brucei alpha tubulin 0.0288 0.29 0.8075
Loa Loa (eye worm) tubulin alpha chain 0.0288 0.29 0.4551
Schistosoma mansoni smad 0.0037 0.017 0.0167
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Echinococcus granulosus neurogenic locus notch protein 4 0.0078 0.0615 0.0695
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0118 0.1051 0.287
Onchocerca volvulus Peroxidase homolog 0.0606 0.6349 1
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Leishmania major alpha tubulin 0.0288 0.29 0.806
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0028 0.0127
Echinococcus granulosus tubulin epsilon chain 0.0212 0.2068 0.2414
Toxoplasma gondii endonuclease IV APN 0.0089 0.0732 0.1975
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0141 0.0134
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.046 0.1213
Loa Loa (eye worm) tubulin alpha-2 chain 0.0288 0.29 0.4551
Echinococcus granulosus Tubulin beta 2C chain 0.0352 0.3591 0.4218
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0066 0.0486 0.6267
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0278 0.0251
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Giardia lamblia Delta tubulin 0.0092 0.0764 0.1536
Giardia lamblia Beta tubulin 0.0352 0.3591 1
Brugia malayi Cytochrome P450 family protein 0.0069 0.051 0.0776
Loa Loa (eye worm) hypothetical protein 0.0288 0.29 0.4551
Toxoplasma gondii EGF family domain-containing protein 0.0078 0.0615 0.1648
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0199 0.0367
Plasmodium vivax delta tubulin, putative 0.0092 0.0764 0.2057
Onchocerca volvulus Peroxidase homolog 0.0606 0.6349 1
Echinococcus granulosus tubulin beta 1 chain 0.0352 0.3591 0.4218
Plasmodium falciparum alpha tubulin 2 0.0288 0.29 0.8058
Onchocerca volvulus 0.0056 0.0373 0.056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0066 0.0486 0.1285
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0531 0.6867
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0028 0.0127
Loa Loa (eye worm) tubulin alpha 2 0.0077 0.0596 0.0912
Echinococcus granulosus Tubulin beta 2C chain 0.0352 0.3591 0.4218
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0032 0.0011
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0028 0.0127
Echinococcus granulosus Tubulin beta 2C chain 0.0352 0.3591 0.4218
Schistosoma mansoni smad1 5 8 and 0.0037 0.017 0.0167
Echinococcus granulosus tubulin subunit TubB 0.0288 0.29 0.3399
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0118 0.1051 0.287
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0273 0.0289
Brugia malayi hypothetical protein 0.0163 0.1539 0.2402
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0028 0.0127
Echinococcus multilocularis lamin dm0 0.0122 0.1095 0.1069
Entamoeba histolytica deoxycytidyl transferase, putative 0.0045 0.0252 0.0616
Echinococcus granulosus Tubulin beta 2C chain 0.0352 0.3591 0.4218
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.0278 0.0251
Brugia malayi hypothetical protein 0.0275 0.2749 0.4313
Loa Loa (eye worm) hypothetical protein 0.012 0.107 0.1661
Trichomonas vaginalis DNA polymerase eta, putative 0.0045 0.0252 0.0515
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0278 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0001
Brugia malayi nuclear receptor RXR 0.0028 0.0068 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0216 0.0413
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0298 0.027
Plasmodium falciparum tubulin epsilon chain, putative 0.0212 0.2068 0.5719
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.051 0.0776
Echinococcus granulosus slit 2 protein 0.0078 0.0615 0.0695
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0066 0.0486 0.0702
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0141 0.0134
Toxoplasma gondii isocitrate dehydrogenase 0.0074 0.057 0.1521
Schistosoma mansoni smad1 5 8 and 0.0037 0.017 0.0167
Loa Loa (eye worm) tubulin beta-2A chain 0.0352 0.3591 0.5643
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.023 0.0239
Onchocerca volvulus Putative cubilin 0.0078 0.0615 0.0942
Brugia malayi MH1 domain containing protein 0.0037 0.017 0.0238
Echinococcus granulosus neuropeptide receptor A26 0.0539 0.5621 0.6622
Echinococcus multilocularis neurogenic locus notch protein 4 0.0078 0.0615 0.0589
Brugia malayi alpha-tubulin 0.0288 0.29 0.4551
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0764 0.1972
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0028 0.0127
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0066 0.0486 0.1275
Loa Loa (eye worm) notch protein 0.0078 0.0615 0.0942
Trypanosoma cruzi zeta tubulin, putative 0.0092 0.0764 0.2066
Entamoeba histolytica tubulin family protein 0.0352 0.3591 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0037 0.017 0.0142
Echinococcus multilocularis neurogenic locus notch protein 0.0078 0.0615 0.0589
Loa Loa (eye worm) tubulin gamma chain 0.0212 0.2068 0.3236
Trypanosoma cruzi epsilon tubulin, putative 0.0212 0.2068 0.5724
Brugia malayi tubulin alpha-2 chain 0.0288 0.29 0.4551
Echinococcus multilocularis fat cadherin tumor suppressor 0.0078 0.0615 0.0589
Loa Loa (eye worm) hypothetical protein 0.006 0.0418 0.063
Echinococcus multilocularis fibropellin Ia 0.0078 0.0615 0.0589
Trichomonas vaginalis tubulin gamma chain, putative 0.0212 0.2068 0.5673
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0078 0.0615 0.0695
Echinococcus multilocularis transfer RNA-Lys 0.0042 0.0219 0.0191
Mycobacterium leprae putative cytochrome p450 0.0024 0.0028 0.0127
Entamoeba histolytica hypothetical protein 0.0163 0.1539 0.4234
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0141 0.0134
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0092 0.0764 1
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Onchocerca volvulus 0.0057 0.0389 0.0584
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0077
Schistosoma mansoni Smad4 0.0037 0.017 0.0167
Echinococcus granulosus lamin 0.0122 0.1095 0.1262
Echinococcus granulosus single minded 2 0.0046 0.0262 0.0276
Loa Loa (eye worm) tubulin beta-4 chain 0.0352 0.3591 0.5643
Onchocerca volvulus 0.0078 0.0615 0.0942
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Mycobacterium leprae cell division protein FtsZ 0.0092 0.0764 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0278 0.041
Echinococcus granulosus protein jagged 2 0.0078 0.0615 0.0695
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.023 0.0202
Loa Loa (eye worm) hypothetical protein 0.0122 0.1095 0.1699
Onchocerca volvulus 0.0606 0.6349 1
Leishmania major alpha tubulin 0.0288 0.29 0.806
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0531 0.1411
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0032 0.0182
Trypanosoma brucei unspecified product 0.0031 0.01 0.028
Echinococcus granulosus jun protein 0.0097 0.0824 0.0942
Echinococcus granulosus tubulin alpha chain 0.0288 0.29 0.3399
Echinococcus multilocularis notch 0.0078 0.0615 0.0589
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0141 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.01 0.028
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0278 0.041
Echinococcus granulosus neurogenic locus notch protein 0.0078 0.0615 0.0695
Echinococcus granulosus delta-like protein 1 0.0078 0.0615 0.0695
Brugia malayi Isocitrate dehydrogenase 0.0074 0.057 0.0871
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Entamoeba histolytica hypothetical protein 0.0163 0.1539 0.4234
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Brugia malayi hypothetical protein 0.0076 0.0594 0.0909
Echinococcus multilocularis tubulin epsilon chain 0.0212 0.2068 0.2045
Leishmania major cytochrome p450-like protein 0.0064 0.046 0.1213
Schistosoma mansoni hypothetical protein 0.0795 0.8406 0.9918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0332 0.0743
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0074 0.057 0.0543
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0278 0.041
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0068 0.0077
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0089 0.0732 0.1966
Schistosoma mansoni alpha tubulin 0.0288 0.29 0.3399
Echinococcus granulosus Tubulin alpha 1 chain 0.0288 0.29 0.3399
Onchocerca volvulus 0.0088 0.0717 0.1103
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0252 0.0701
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0068 0.0077
Schistosoma mansoni hypothetical protein 0.0041 0.0212 0.0217
Echinococcus multilocularis protein jagged 2 0.0078 0.0615 0.0589
Brugia malayi Animal haem peroxidase family protein 0.0606 0.6349 1
Leishmania major beta tubulin 0.0352 0.3591 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0278 0.041
Echinococcus granulosus intermediate filament protein 0.0122 0.1095 0.1262
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0089 0.0732 0.1126
Brugia malayi Niemann-Pick C1 protein precursor 0.0114 0.1007 0.1561
Toxoplasma gondii alpha-tubulin I, putative 0.0288 0.29 0.806
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0037 0.017 0.0167
Onchocerca volvulus Dual oxidase homolog 0.0606 0.6349 1
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Trypanosoma cruzi beta tubulin, putative 0.0352 0.3591 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0252 0.3122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Echinococcus granulosus tubulin alpha chain 0.0288 0.29 0.3399
Schistosoma mansoni microtubule-associated protein tau 0.0801 0.8475 1
Treponema pallidum cell division protein FtsZ 0.0092 0.0764 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0278 0.0251
Loa Loa (eye worm) hypothetical protein 0.0045 0.0252 0.0368
Echinococcus multilocularis Tubulin alpha 1 chain 0.0288 0.29 0.2879
Brugia malayi Tubulin beta-1 chain 0.0352 0.3591 0.5643
Echinococcus granulosus lamin dm0 0.0122 0.1095 0.1262
Echinococcus granulosus protein jagged 2 0.0078 0.0615 0.0695
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Loa Loa (eye worm) MH2 domain-containing protein 0.0547 0.5714 0.8997
Toxoplasma gondii LsmAD domain-containing protein 0.0118 0.105 0.2868
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0037 0.017 0.0142
Echinococcus granulosus geminin 0.0795 0.8406 0.9918
Schistosoma mansoni cell polarity protein 0.0078 0.0615 0.0695
Trypanosoma cruzi PAB1-binding protein , putative 0.0118 0.105 0.2868
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0141 0.0317
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Echinococcus granulosus Tubulin alpha 1 chain 0.0288 0.29 0.3399
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0298 0.0646
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0216 0.0602
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.01 0.028
Leishmania major hypothetical protein, conserved 0.0118 0.105 0.2868
Onchocerca volvulus 0.0078 0.0615 0.0942
Plasmodium falciparum ataxin-2 like protein, putative 0.0118 0.105 0.2859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Brugia malayi notch-like transmembrane receptor 0.0078 0.0615 0.0942
Echinococcus granulosus tubulin alpha chain 0.0288 0.29 0.3399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0089 0.0732 0.1126
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0373 0.056
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0045 0.0252 0.0627
Brugia malayi Intermediate filament tail domain containing protein 0.0122 0.1095 0.1699
Echinococcus granulosus notch 0.0078 0.0615 0.0695
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0114 0.1007 0.2739
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0278 0.041
Onchocerca volvulus 0.0042 0.0219 0.0316
Giardia lamblia Epsilon tubulin 0.0092 0.0764 0.1536
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0066 0.0486 0.1285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0001
Schistosoma mansoni terminal deoxycytidyl transferase 0.0045 0.0252 0.0264
Leishmania major beta tubulin 0.0352 0.3591 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0118 0.1051 0.1025
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0074 0.057 0.1521
Brugia malayi Animal haem peroxidase family protein 0.0606 0.6349 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0028 0.0127
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0059 0.0406 0.0448
Trypanosoma brucei tubulin delta chain 0.0092 0.0764 0.2129
Leishmania major DNA polymerase eta, putative 0.0045 0.0252 0.0627
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0045 0.0252 0.0224
Plasmodium falciparum tubulin delta chain, putative 0.0092 0.0764 0.2057
Brugia malayi steroid hormone receptor 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Onchocerca volvulus Peroxidasin homolog 0.0606 0.6349 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0332 0.0852
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Onchocerca volvulus 0.0606 0.6349 1
Trypanosoma brucei beta tubulin 0.0212 0.2068 0.5758
Toxoplasma gondii beta-tubulin, putative 0.0352 0.3591 1
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0531 0.0595
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0028 0.0127
Plasmodium falciparum ataxin-2 like protein, putative 0.0118 0.105 0.2859
Trypanosoma brucei beta tubulin 0.0352 0.3591 1
Echinococcus granulosus tubulin delta chain 0.0092 0.0764 0.0871
Echinococcus granulosus tubulin alpha 3 chain 0.0288 0.29 0.3399
Onchocerca volvulus 0.0077 0.0597 0.0913
Onchocerca volvulus 0.0159 0.1496 0.2334
Trypanosoma cruzi PAB1-binding protein , putative 0.0118 0.105 0.2868
Trypanosoma brucei tubulin gamma chain 0.0212 0.2068 0.5758
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0278 0.0251
Trichomonas vaginalis set domain proteins, putative 0.0275 0.2754 0.7624
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0278 0.0296
Loa Loa (eye worm) animal heme peroxidase 0.0606 0.6349 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0216 0.0413
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0352 0.3591 0.3573
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0332 0.0304
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0118 0.1051 0.163
Echinococcus granulosus tumor protein p63 0.0392 0.4029 0.4737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0332 0.0743
Leishmania major beta tubulin 0.0352 0.3591 1
Trichomonas vaginalis tubulin beta chain, putative 0.012 0.1068 0.2833
Brugia malayi Pre-SET motif family protein 0.0242 0.2391 0.3748
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0332 0.0852
Trichomonas vaginalis tubulin alpha chain, putative 0.0212 0.2068 0.5673
Echinococcus multilocularis protein jagged 1 0.0078 0.0615 0.0589
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0116 0.1026 0.1182
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0028 0.0127
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0531 0.0595
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Schistosoma mansoni jun-related protein 0.0079 0.0626 0.0707
Leishmania major gamma-tubulin 0.0212 0.2068 0.5724
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0278 0.0251
Schistosoma mansoni hypothetical protein 0.0047 0.0278 0.0296
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0074 0.057 0.1511
Schistosoma mansoni tubulin subunit alpha 0.0288 0.29 0.3399
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Schistosoma mansoni hypothetical protein 0.0056 0.0373 0.0408
Loa Loa (eye worm) Notch2 0.0078 0.0615 0.0942
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0298 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0278 0.041
Echinococcus multilocularis microtubule associated protein 2 0.0801 0.8475 0.8471
Giardia lamblia Alpha-tubulin 0.0288 0.29 0.793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0199 0.0367
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0028 0.0127
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0089 0.0732 0.9564
Brugia malayi Animal haem peroxidase family protein 0.0606 0.6349 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0074 0.057 0.7394
Giardia lamblia Alpha-tubulin 0.0288 0.29 0.793
Brugia malayi hypoxia-induced factor 1 0.0175 0.1665 0.26
Leishmania major alpha tubulin 0.0288 0.29 0.806
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0332 0.0924
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0066 0.0486 0.1275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0001
Loa Loa (eye worm) hypothetical protein 0.0368 0.3769 0.5924
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Onchocerca volvulus 0.0559 0.584 0.9196
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0028 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0028 0.0127
Echinococcus granulosus tubulin alpha 1C chain 0.0288 0.29 0.3399
Brugia malayi Tubulin beta chain 0.012 0.1068 0.1657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0133 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0028 0.0127
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.1051 0.2785
Trichomonas vaginalis tubulin, putative 0.0352 0.3591 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0332 0.0359
Trichomonas vaginalis tubulin, putative 0.0092 0.0764 0.1972
Loa Loa (eye worm) hypothetical protein 0.0088 0.0717 0.1103
Echinococcus multilocularis protein jagged 1 0.0078 0.0615 0.0589
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0028 0.0127
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0064 0.046 0.5924
Trichomonas vaginalis ap endonuclease, putative 0.0066 0.0486 0.1181
Plasmodium falciparum tubulin beta chain 0.0352 0.3591 1
Entamoeba histolytica tubulin family protein 0.0352 0.3591 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.012 0.1068 0.2833
Leishmania major zeta tubulin, putative 0.0092 0.0764 0.2066
Echinococcus multilocularis Tubulin beta 2C chain 0.0352 0.3591 0.3573
Brugia malayi tubulin alpha chain - mouse 0.0288 0.29 0.4551
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0216 0.0413
Loa Loa (eye worm) tubulin alpha 2 0.0196 0.19 0.2971
Schistosoma mansoni laminin gamma-3 chain 0.0078 0.0615 0.0695
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0717 0.0816
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Echinococcus multilocularis tubulin alpha chain 0.0288 0.29 0.2879
Echinococcus multilocularis musashi 0.0122 0.1095 0.1069
Echinococcus granulosus peroxidasin 0.0606 0.6349 0.7483
Trypanosoma brucei alpha tubulin, putative 0.012 0.1068 0.2973
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0092 0.0764 0.2066
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0089 0.0732 0.9564
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0032 0.0011
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0028 0.0127
Trypanosoma brucei epsilon tubulin 0.0212 0.2068 0.5758
Mycobacterium tuberculosis Cell division protein FtsZ 0.0092 0.0764 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0278 0.041
Giardia lamblia Beta tubulin 0.0352 0.3591 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0141 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Echinococcus multilocularis tubulin subunit beta 0.0352 0.3591 0.3573
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Echinococcus multilocularis slit 2 protein 0.0078 0.0615 0.0589
Trypanosoma brucei epsilon tubulin 0.0212 0.2068 0.5758
Echinococcus multilocularis Tubulin beta 2C chain 0.0352 0.3591 0.3573
Loa Loa (eye worm) hypothetical protein 0.0037 0.0169 0.0236
Schistosoma mansoni peroxidasin 0.0606 0.6349 0.7483
Echinococcus granulosus neuropeptide s receptor 0.0539 0.5621 0.6622
Loa Loa (eye worm) hypothetical protein 0.004 0.0197 0.0281
Onchocerca volvulus 0.0078 0.0615 0.0942
Onchocerca volvulus 0.0122 0.1095 0.1699
Trypanosoma brucei cytochrome P450, putative 0.0064 0.046 0.1282
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0028 0.0127
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0066 0.0477 0.0724
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0028 0.0127
Echinococcus multilocularis dna polymerase eta 0.0045 0.0252 0.0224
Brugia malayi PAS domain containing protein 0.0056 0.0378 0.0568
Brugia malayi Smad1 0.0037 0.017 0.0238
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0141 0.0113
Loa Loa (eye worm) tubulin beta chain 0.0352 0.3591 0.5643
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.0278 0.0296
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.046 0.0698
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0273 0.0289
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0028 0.0127
Brugia malayi bHLH-PAS transcription factor 0.0042 0.0219 0.0316
Schistosoma mansoni tubulin subunit epsilon 0.0212 0.2068 0.2414
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0053 0.0341 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0103 0.0094
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Brugia malayi cytoplasmic intermediate filament protein 0.0066 0.0477 0.0724
Schistosoma mansoni smad1 5 8 and 0.0037 0.017 0.0167
Echinococcus multilocularis tubulin alpha 3 chain 0.0288 0.29 0.2879
Schistosoma mansoni single-minded 0.0056 0.0378 0.0415
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.1051 0.2785
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0252 0.0627
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0028 0.0127
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0252 0.0627
Trypanosoma cruzi epsilon tubulin, putative 0.0212 0.2068 0.5724
Echinococcus multilocularis neural cadherin 0.0078 0.0615 0.0589
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0288 0.29 0.8037
Trichomonas vaginalis ap endonuclease, putative 0.0066 0.0486 0.1181
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.046 0.0698
Plasmodium vivax tubulin alpha chain, putative 0.0288 0.29 0.8058
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0186 0.0443
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Trichomonas vaginalis tubulin alpha chain, putative 0.012 0.1068 0.2833
Loa Loa (eye worm) tubulin beta-1 chain 0.0352 0.3591 0.5643
Loa Loa (eye worm) pax transcription factor protein 2 0.0559 0.584 0.9196
Brugia malayi Calcium binding EGF domain containing protein 0.0078 0.0615 0.0942
Plasmodium vivax tubulin gamma chain, putative 0.0212 0.2068 0.5719
Leishmania major beta tubulin 0.0352 0.3591 1
Giardia lamblia Gamma tubulin 0.0212 0.2068 0.5438
Plasmodium vivax SET domain protein, putative 0.0035 0.0141 0.0306
Toxoplasma gondii exonuclease III APE 0.0066 0.0486 0.1285
Plasmodium falciparum tubulin gamma chain 0.0212 0.2068 0.5719
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0252 0.0701
Mycobacterium ulcerans endonuclease IV 0.0089 0.0732 0.9564
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0278 0.041
Loa Loa (eye worm) transcription factor SMAD2 0.0547 0.5714 0.8997
Loa Loa (eye worm) intermediate filament protein 0.0122 0.1095 0.1699
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0077
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0163 0.1539 0.1515
Giardia lamblia GTOR 0.0052 0.0332 0.024
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0531 0.0504
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0252 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.1051 0.2785
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0141 0.0134
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0278 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0186 0.033
Plasmodium vivax ataxin-2 like protein, putative 0.0118 0.105 0.2859
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.01 0.028
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0028 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Echinococcus granulosus fibropellin Ia 0.0078 0.0615 0.0695
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0068 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0001
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0145 0.0212
Schistosoma mansoni transcription factor LCR-F1 0.0163 0.1539 0.1789
Schistosoma mansoni lamin 0.0122 0.1095 0.1262
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0066 0.0486 0.1275
Echinococcus multilocularis smad 0.0037 0.017 0.0142
Leishmania major DNA polymerase kappa, putative 0.0045 0.0252 0.0627
Brugia malayi Cadherin domain containing protein 0.0078 0.0615 0.0942
Echinococcus granulosus beta tubulin 0.0352 0.3591 0.4218
Brugia malayi Delta serrate ligand family protein 0.0078 0.0615 0.0942
Trichomonas vaginalis tubulin, putative 0.012 0.1068 0.2833
Brugia malayi ecdysteroid receptor 0.0047 0.0278 0.041
Loa Loa (eye worm) animal heme peroxidase 0.0606 0.6349 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Chlamydia trachomatis endonuclease IV 0.0089 0.0732 1
Brugia malayi Cytochrome P450 family protein 0.0064 0.046 0.0698
Brugia malayi GCC2 and GCC3 family protein 0.0078 0.0615 0.0942
Echinococcus multilocularis tubulin alpha 1C chain 0.0288 0.29 0.2879
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0068 0.0039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0332 0.0494
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0212 0.0305
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0047 0.0278 0.041
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0059 0.0406 0.0379
Schistosoma mansoni tubulin subunit alpha 0.0288 0.29 0.3399
Schistosoma mansoni hypothetical protein 0.0047 0.0278 0.0296
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0028 0.0127
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Loa Loa (eye worm) hypothetical protein 0.0049 0.0298 0.0441
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0097 0.0824 0.0942
Brugia malayi Peroxidasin 0.0606 0.6349 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0066 0.0486 0.1285
Schistosoma mansoni ap endonuclease 0.0066 0.0486 0.0542
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0028 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0419 0.0632
Trypanosoma brucei alpha tubulin 0.0288 0.29 0.8075
Leishmania major epsilon tubulin, putative 0.0212 0.2068 0.5724
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0278 0.041
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0278 0.0296
Trichomonas vaginalis tubulin gamma chain, putative 0.0092 0.0764 0.1972
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Schistosoma mansoni alpha tubulin 0.0288 0.29 0.3399
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0252 0.0701
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0045 0.0252 0.0264
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0118 0.1051 0.287
Schistosoma mansoni hypothetical protein 0.0163 0.1539 0.1789
Echinococcus multilocularis expressed conserved protein 0.0107 0.0932 0.0906
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0252 0.0627
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0419 0.0632
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0332 0.0852
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0531 0.6867
Brugia malayi CHE-14 protein 0.0049 0.0298 0.0441
Echinococcus multilocularis Smad4 0.0037 0.017 0.0142
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0332 0.0841
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0278 0.041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0066 0.0486 0.1354
Toxoplasma gondii beta-1 tubulin, putative 0.0352 0.3591 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0216 0.0527
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0332 0.0841
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0278 0.0296
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0531 0.1411
Brugia malayi nuclear receptor NHR-88 0.0047 0.0278 0.041
Brugia malayi hypothetical protein 0.0159 0.1496 0.2334
Echinococcus granulosus mitogen activated protein kinase 0.0118 0.1051 0.121
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.023 0.0334
Schistosoma mansoni tubulin subunit gamma 0.0212 0.2068 0.2414
Echinococcus multilocularis tubulin alpha 0.0212 0.2068 0.2045
Onchocerca volvulus 0.0047 0.0278 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0249 0.0507
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0074 0.057 0.0641
Giardia lamblia Beta tubulin 0.0352 0.3591 1
Schistosoma mansoni hypothetical protein 0.0079 0.0626 0.0707
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Schistosoma mansoni tubulin subunit alpha 0.0288 0.29 0.3399
Brugia malayi follicle stimulating hormone receptor 0.0272 0.2718 0.4264
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Leishmania major beta tubulin 0.0352 0.3591 1
Leishmania major alpha tubulin 0.0288 0.29 0.806
Giardia lamblia High cysteine protein 0.0078 0.0615 0.1089
Trichomonas vaginalis tubulin epsilon chain, putative 0.0288 0.29 0.8037
Loa Loa (eye worm) hypothetical protein 0.0057 0.0389 0.0584
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0278 0.0296
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0531 0.0595
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0942
Schistosoma mansoni alpha tubulin 0.0288 0.29 0.3399
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0717 0.1103
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0278 0.041
Onchocerca volvulus Neurogenic locus notch homolog 0.0078 0.0615 0.0942
Loa Loa (eye worm) hypoxia-induced factor 1 0.0175 0.1665 0.26
Loa Loa (eye worm) MH2 domain-containing protein 0.0037 0.017 0.0238
Schistosoma mansoni intermediate filament proteins 0.0122 0.1095 0.1262
Loa Loa (eye worm) tubulin beta chain 0.0092 0.0764 0.1178
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0252 0.0701
Brugia malayi Tubulin alpha-2 chain 0.0288 0.29 0.4551
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Trichomonas vaginalis tubulin gamma chain, putative 0.0212 0.2068 0.5673
Echinococcus multilocularis neurogenic locus protein delta 0.0078 0.0615 0.0589
Leishmania major beta tubulin 0.0352 0.3591 1
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.0278 0.0296
Onchocerca volvulus Slit protein homolog 0.0078 0.0615 0.0942
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0216 0.0527
Trypanosoma brucei alpha tubulin 0.0288 0.29 0.8075
Brugia malayi Pre-SET motif family protein 0.0035 0.0141 0.0193
Echinococcus granulosus microtubule associated protein 2 0.0801 0.8475 1
Echinococcus multilocularis hypothetical protein 0.0288 0.29 0.2879
Brugia malayi Cadherin domain containing protein 0.0078 0.0615 0.0942
Brugia malayi hypothetical protein 0.0028 0.0068 0.0077
Echinococcus multilocularis tubulin alpha chain 0.0288 0.29 0.2879
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0028 0.0127
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0278 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0278 0.041
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0074 0.057 0.1588
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Brugia malayi hypothetical protein 0.0189 0.1824 0.2852
Loa Loa (eye worm) hypothetical protein 0.0189 0.1824 0.2852
Echinococcus multilocularis beta tubulin 0.0352 0.3591 0.3573
Schistosoma mansoni tubulin subunit alpha 0.0092 0.0764 0.0871
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0278 0.0251
Schistosoma mansoni hypothetical protein 0.0078 0.0615 0.0695
Loa Loa (eye worm) hypothetical protein 0.0035 0.0141 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0278 0.041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0077
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0028 0.0127
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Echinococcus granulosus TGF beta signal transducer SmadC 0.0037 0.017 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0252 0.0701
Plasmodium vivax tubulin alpha chain, putative 0.0288 0.29 0.8058
Entamoeba histolytica tubulin alpha chain, putative 0.0288 0.29 0.8058
Echinococcus multilocularis protein patched 0.0049 0.0298 0.027
Echinococcus granulosus smad 0.0037 0.017 0.0167
Onchocerca volvulus Chorion peroxidase homolog 0.0606 0.6349 1
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Leishmania major alpha tubulin 0.0288 0.29 0.806
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0196 0.19 0.5196
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0278 0.0296
Echinococcus multilocularis Tubulin beta 2C chain 0.0352 0.3591 0.3573
Echinococcus multilocularis tumor protein p63 0.0392 0.4029 0.4013
Echinococcus multilocularis tubulin alpha 3 chain 0.0288 0.29 0.2879
Echinococcus multilocularis tubulin subunit TubB 0.0288 0.29 0.2879
Trypanosoma cruzi tubulin delta chain 0.0092 0.0764 0.2066
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0278 0.0296
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0074 0.057 0.1521
Schistosoma mansoni septate junction protein 0.0078 0.0615 0.0695
Schistosoma mansoni tubulin subunit beta 0.0352 0.3591 0.4218
Schistosoma mansoni notch 0.0078 0.0615 0.0695
Echinococcus multilocularis tubulin alpha chain 0.0288 0.29 0.2879
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0068 0.0047
Giardia lamblia Kinase, CMGC MAPK 0.0118 0.1051 0.2393
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0028 0.0127
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0252 0.3122
Brugia malayi hypothetical protein 0.0141 0.1301 0.2025
Loa Loa (eye worm) hypothetical protein 0.0114 0.1007 0.1561
Echinococcus granulosus mitogen activated protein kinase 3 0.0118 0.1051 0.121
Schistosoma mansoni ap endonuclease 0.0066 0.0486 0.0542
Brugia malayi EGF-like domain containing protein 0.0078 0.0615 0.0942
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0278 0.0296
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0118 0.1051 0.287
Schistosoma mansoni tubulin subunit beta 0.0092 0.0764 0.0871
Onchocerca volvulus 0.012 0.1068 0.1657
Schistosoma mansoni hypothetical protein 0.0795 0.8406 0.9918
Brugia malayi exodeoxyribonuclease III family protein 0.0066 0.0486 0.0738
Trichomonas vaginalis tubulin, putative 0.012 0.1068 0.2833
Brugia malayi Muscle positioning protein 4 0.0078 0.0615 0.0942
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0074 0.057 0.1588
Echinococcus multilocularis Niemann Pick C1 protein 0.0163 0.154 0.1516
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0028 0.0127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0278 0.0296
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0045 0.0252 0.0264
Echinococcus multilocularis survival motor neuron protein 1 0.0275 0.2749 0.2729
Trypanosoma brucei unspecified product 0.0031 0.01 0.028
Brugia malayi Animal haem peroxidase family protein 0.0606 0.6349 1
Leishmania major beta tubulin 0.0352 0.3591 1
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0216 0.0413
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0032 0.009
Echinococcus granulosus neurogenic locus protein delta 0.0078 0.0615 0.0695
Trichomonas vaginalis tubulin epsilon chain, putative 0.0352 0.3591 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0169 0.1596 0.2492
Echinococcus multilocularis Tubulin alpha 1 chain 0.0288 0.29 0.2879
Mycobacterium ulcerans putative regulatory protein 0.0042 0.0219 0.2683
Leishmania major beta tubulin 0.0352 0.3591 1
Echinococcus granulosus neural cadherin 0.0078 0.0615 0.0695
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0092 0.0764 0.2066
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0278 0.0251
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0066 0.0486 0.6267
Leishmania major alpha tubulin 0.0288 0.29 0.806
Loa Loa (eye worm) hypothetical protein 0.0159 0.1496 0.2334
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0332 0.0494
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.046 0.1213
Echinococcus multilocularis neuropeptide s receptor 0.0539 0.5621 0.5609
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0298 0.0441
Leishmania major beta tubulin 0.0352 0.3591 1
Echinococcus granulosus protein jagged 1 0.0078 0.0615 0.0695
Trypanosoma brucei PAB1-binding protein , putative 0.0118 0.105 0.2924
Brugia malayi nuclear hormone receptor 0.0047 0.0278 0.041
Echinococcus granulosus protein jagged 1 0.0078 0.0615 0.0695
Echinococcus granulosus alpha tubulin 0.0288 0.29 0.3399
Trypanosoma brucei zeta tubulin 0.0092 0.0764 0.2129
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0053 0.0341 0.0314
Schistosoma mansoni lamin 0.0122 0.1095 0.1262
Trichomonas vaginalis tubulin epsilon chain, putative 0.0288 0.29 0.8037
Schistosoma mansoni coup transcription factor 0.0047 0.0278 0.0296
Plasmodium falciparum alpha tubulin 1 0.0288 0.29 0.8058
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0078 0.0615 0.0942
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0212 0.2068 0.5724
Loa Loa (eye worm) MH1 domain-containing protein 0.0037 0.017 0.0238
Trichomonas vaginalis tubulin beta chain, putative 0.0288 0.29 0.8037
Trypanosoma cruzi alpha tubulin, putative 0.0288 0.29 0.806
Leishmania major beta tubulin 0.0352 0.3591 1
Echinococcus granulosus tubulin alpha chain 0.0288 0.29 0.3399
Entamoeba histolytica tubulin gamma chain 0.0212 0.2068 0.5719
Trichomonas vaginalis tubulin alpha chain, putative 0.012 0.1068 0.2833
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0028 0.0127
Echinococcus granulosus Niemann Pick C1 protein 0.0114 0.1007 0.1159
Echinococcus multilocularis tubulin beta 1 chain 0.0352 0.3591 0.3573
Echinococcus granulosus neurogenic locus notch protein 0.0078 0.0615 0.0695
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0332 0.0852
Leishmania major alpha tubulin 0.0288 0.29 0.806
Echinococcus granulosus peroxisome assembly protein 26 0.0288 0.29 0.3399
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0097 0.0824 0.0798
Entamoeba histolytica hypothetical protein 0.0163 0.1539 0.4234
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0068 0.0047
Echinococcus granulosus tubulin alpha 0.0212 0.2068 0.2414
Brugia malayi Calcium binding EGF domain containing protein 0.0078 0.0615 0.0942
Brugia malayi Cell division protein ftsZ 0.0092 0.0764 0.1178
Loa Loa (eye worm) hypothetical protein 0.0095 0.0795 0.1227
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0066 0.0486 0.0542
Echinococcus multilocularis tubulin gamma 1 chain 0.0212 0.2068 0.2045
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0032 0.0182
Echinococcus granulosus Smad4 0.0037 0.017 0.0167
Loa Loa (eye worm) hypothetical protein 0.006 0.0419 0.0632
Trypanosoma brucei beta tubulin 0.0352 0.3591 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0118 0.1051 0.287
Onchocerca volvulus Peroxidasin homolog 0.0606 0.6349 1
Entamoeba histolytica tubulin alpha-1 chain 0.0288 0.29 0.8058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0278 0.0296
Schistosoma mansoni hypothetical protein 0.0047 0.0278 0.0296
Echinococcus granulosus tubulin alpha 3 chain 0.0288 0.29 0.3399
Echinococcus multilocularis tubulin alpha chain 0.0288 0.29 0.2879
Echinococcus granulosus tubulin alpha 1C chain 0.0288 0.29 0.3399
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0163 0.1539 0.1789
Trichomonas vaginalis tubulin beta chain, putative 0.0352 0.3591 1
Onchocerca volvulus 0.0606 0.6349 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.01 0.0085
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0122 0.1095 0.1699
Echinococcus multilocularis neurogenic locus protein delta 0.0078 0.0615 0.0589
Loa Loa (eye worm) hypothetical protein 0.0606 0.6349 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0717 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0103 0.0094
Schistosoma mansoni patched 1 0.0049 0.0298 0.0319
Loa Loa (eye worm) hypothetical protein 0.0196 0.19 0.2971
Brugia malayi isocitrate dehydrogenase 0.0074 0.057 0.0871
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0278 0.0296
Echinococcus multilocularis jun protein 0.0097 0.0824 0.0798
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0028 0.0127
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0028 0.0127
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0252 0.0368

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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