Detailed information for compound 304587

Basic information

Technical information
  • TDR Targets ID: 304587
  • Name: (E)-3-(4-bromophenyl)-N-methyl-3-pyridin-3-yl prop-2-en-1-amine
  • MW: 303.197 | Formula: C15H15BrN2
  • H donors: 1 H acceptors: 1 LogP: 3.44 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC/C=C(/c1cccnc1)\c1ccc(cc1)Br
  • InChi: 1S/C15H15BrN2/c1-17-10-8-15(13-3-2-9-18-11-13)12-4-6-14(16)7-5-12/h2-9,11,17H,10H2,1H3/b15-8+
  • InChiKey: AZFZKANGXPSDEA-OVCLIPMQSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-3-(4-bromophenyl)-N-methyl-3-(3-pyridyl)prop-2-en-1-amine
  • (E)-3-(4-bromophenyl)-N-methyl-3-(3-pyridyl)-2-propen-1-amine
  • (E)-3-(4-bromophenyl)-N-methyl-3-pyridin-3-yl-prop-2-en-1-amine
  • [(E)-3-(4-bromophenyl)-3-(3-pyridyl)allyl]-methyl-amine
  • norzimelidine
  • [(E)-3-(4-bromophenyl)-3-(3-pyridyl)prop-2-enyl]-methyl-amine
  • 56775-85-0
  • 2-Propen-1-amine, 3-(4-bromophenyl)-N-methyl-3-(3-pyridinyl)-
  • 3-(4-Bromophenyl)-N-methyl-3-(3-pyridinyl)-2-propen-1-amine
  • Norzimeldine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0131 0.0256 0.1629
Plasmodium falciparum thioredoxin reductase 0.002 0.0013 0.0049
Trypanosoma brucei histone deacetylase 3 0.0075 0.0135 0.0477
Onchocerca volvulus 0.0042 0.0062 0.0062
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0015 0.017
Brugia malayi hypothetical protein 0.002 0.0013 0.0018
Brugia malayi Cytochrome P450 family protein 0.0031 0.0039 0.0053
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0015 0.002
Echinococcus multilocularis GPCR, family 2 0.0016 0.0005 0.0009
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0039 0.0247
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Trypanosoma brucei unspecified product 0.0019 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0017 0.0482
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0038 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0015 0.0021
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0017 0.0043
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) glutathione reductase 0.0057 0.0095 0.0604
Leishmania major hypothetical protein, unknown function 0.0016 0.0006 0.0008
Onchocerca volvulus 0.0028 0.0031 0.0031
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0214 0.046
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.0297 0.0408
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0031 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Loa Loa (eye worm) cytochrome P450 0.0021 0.0016 0.01
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.009 0.0675
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0063
Echinococcus granulosus death domain containing protein 0.0017 0.0008 0.0018
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0015 0.0033
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0031 0.0195
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0062 0.0229
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0004 0.0055
Giardia lamblia Histone deacetylase 0.0216 0.0444 0.16
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Echinococcus multilocularis lamin dm0 0.003 0.0037 0.0067
Trypanosoma cruzi histone deacetylase 1, putative 0.0216 0.0444 0.1628
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0046
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0232
Brugia malayi G-protein coupled receptor 0.0028 0.0031 0.0042
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0013 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.037 0.0797
Loa Loa (eye worm) hypothetical protein 0.0304 0.0636 0.4051
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0016 0.0026
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Leishmania major cytochrome p450-like protein 0.0031 0.0039 0.0131
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.009 0.0611
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0368 0.2343
Brugia malayi hypothetical protein 0.0042 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0016 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0216 0.0444 0.2827
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0002 0.0002
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0015 0.0033
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0031 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0031 0.0056
Entamoeba histolytica hypothetical protein 0.0021 0.0015 0.0232
Brugia malayi neuropeptide F receptor 0.0028 0.0031 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0304 0.0636 1
Echinococcus multilocularis survival motor neuron protein 1 0.0731 0.1571 0.2877
Toxoplasma gondii exonuclease III APE 0.0021 0.0017 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0131 0.102
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni patched 1 0.0131 0.0256 0.0552
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Onchocerca volvulus 0.0018 0.0011 0.001
Brugia malayi larval opioid receptor 0.0028 0.0031 0.0042
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0015 0.0033
Loa Loa (eye worm) TAR-binding protein 0.0193 0.0393 0.25
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0031 0.0066
Brugia malayi topoisomerase 0.0021 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus multilocularis RUN 0.0048 0.0074 0.0136
Schistosoma mansoni myosin xvIII 0.0028 0.0031 0.0066
Trypanosoma cruzi histone deacetylase 1, putative 0.0216 0.0444 0.1628
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0031 0.0056
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0034 0.0103
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0031 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Toxoplasma gondii histone deacetylase HDAC2 0.0216 0.0444 0.1638
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0004 0.0055
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0255 0.208
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0016 0.0044
Echinococcus granulosus Chromobox protein 3 0.0014 0 0.0001
Brugia malayi hypothetical protein 0.0048 0.0074 0.0102
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0013 0.0049
Echinococcus multilocularis tar DNA binding protein 0.0193 0.0393 0.072
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1251 0.271 1
Echinococcus granulosus intermediate filament protein 0.003 0.0037 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Brugia malayi putative neuropeptide receptor 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0056
Onchocerca volvulus 0.0022 0.0017 0.0017
Plasmodium vivax importin-beta 2, putative 0.0029 0.0034 0.0123
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0031 0.0031
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0017 0.0036
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0731 0.1571 1
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0031 0.0056
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0009
Mycobacterium ulcerans oxidoreductase 0.0042 0.0062 0.0392
Echinococcus multilocularis geminin 0.0175 0.0354 0.0649
Schistosoma mansoni lamin 0.003 0.0037 0.0079
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0381 0.0821
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0013 0.0049
Brugia malayi PAS domain containing protein 0.0059 0.0099 0.0136
Toxoplasma gondii hypothetical protein 0.0031 0.0038 0.0139
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0043
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.0522 0.3322
Echinococcus granulosus histone deacetylase 7 0.0075 0.0135 0.029
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Plasmodium vivax telomerase reverse transcriptase, putative 0.1251 0.271 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Onchocerca volvulus 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0096
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0017 0.0036
Trichomonas vaginalis DNA polymerase I, putative 0.0018 0.001 0.0165
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0015 0.0028
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Brugia malayi Pre-SET motif family protein 0.0037 0.0051 0.0069
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0015 0.0055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Trypanosoma brucei histone deacetylase 2 0.0075 0.0135 0.0477
Plasmodium vivax histone deacetylase 1, putative 0.0216 0.0444 0.1638
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0017 0.0036
Loa Loa (eye worm) doublecortin family protein 0.0048 0.0074 0.0472
Schistosoma mansoni hypothetical protein 0.0048 0.0074 0.016
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi RNA binding protein 0.0193 0.0393 0.0541
Loa Loa (eye worm) hypothetical protein 0.0197 0.0402 0.2556
Brugia malayi ecdysteroid receptor 0.0021 0.0015 0.0021
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0022 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0021
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0031 0.0066
Schistosoma mansoni polycystin 1-related 0.0048 0.0074 0.016
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0013 0.0049
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0027
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Brugia malayi Patched related family protein 10 0.0018 0.0011 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0016 0.0044
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0013 0.0944
Schistosoma mansoni histone deacetylase hda2 0.0075 0.0135 0.029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus Ankyrin 0.0018 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi protein C24B5.3 0.0018 0.0011 0.0014
Plasmodium falciparum glutathione reductase 0.002 0.0013 0.0049
Echinococcus multilocularis microtubule associated protein 2 0.2133 0.4641 0.8502
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0031 0.0066
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0005 0.0029
Plasmodium falciparum transporter, putative 0.0031 0.0038 0.0139
Onchocerca volvulus 0.0018 0.0011 0.001
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0556 0.1187 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Brugia malayi Niemann-Pick C1 protein precursor 0.0304 0.0636 0.0876
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Thioredoxin reductase 0.0057 0.0095 0.0131
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Plasmodium falciparum histone deacetylase 2 0.0075 0.0135 0.0496
Loa Loa (eye worm) histone deacetylase 7A 0.0075 0.0135 0.0856
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0013 0.0018
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0016 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0015 0.0247
Entamoeba histolytica DNA-directed DNA polymerase, putative 0.0018 0.001 0.0155
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0061 0.0132
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0106
Onchocerca volvulus 0.0043 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0037 0.0232
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0031 0.0195
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0016 0.0006 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0016
Plasmodium falciparum plastid replication-repair enzyme 0.0018 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0081 0.1355
Brugia malayi nuclear hormone receptor 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0016 0.0044
Brugia malayi Histone deacetylase 1 0.0216 0.0444 0.0611
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0021
Onchocerca volvulus 0.0182 0.037 0.0369
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0135 0.029
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0015 0.0055
Leishmania major cytochrome p450-like protein 0.0021 0.0016 0.0046
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0017 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0383 0.0809 0.515
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0017 0.0031
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0054 0.0074
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0016 0.0257
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0017 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0013 0.0049
Plasmodium vivax histone deacetylase, putative 0.0075 0.0135 0.0496
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0016 0.0044
Schistosoma mansoni DNA polymerase I 0.0018 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.016 0.032 0.2039
Plasmodium vivax SET domain protein, putative 0.0037 0.0051 0.0186
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0046
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.005 0.008 0.0508
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0095 0.0205
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0039 0.0247
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.008 0.0508
Brugia malayi GnHR receptor homolog 0.0028 0.0031 0.0042
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0031 0.0066
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0016 0.0026
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0015 0.0043
Brugia malayi Cytochrome P450 family protein 0.0021 0.0016 0.0022
Plasmodium vivax plastid replication-repair enzyme, putative 0.0018 0.001 0.0036
Trypanosoma brucei mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0017
Echinococcus multilocularis serotonin receptor 0.0028 0.0031 0.0056
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0074 0.016
Brugia malayi ORL1-like opioid receptor 0.0028 0.0031 0.0042
Trypanosoma brucei mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0017
Onchocerca volvulus 0.0021 0.0015 0.0015
Brugia malayi SET domain containing protein 0.0016 0.0005 0.0006
Echinococcus multilocularis 0.0042 0.0062 0.0114
Onchocerca volvulus 0.0022 0.0017 0.0017
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0031 0.0056
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0016 0.0026
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0031 0.0066
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0031 0.0066
Echinococcus granulosus microtubule associated protein 2 0.2133 0.4641 1
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0031 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.0229
Toxoplasma gondii hypothetical protein 0.0018 0.0011 0.0038
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0009 0.0138
Onchocerca volvulus Protein patched homolog 0.0018 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0015 0.0096
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Trypanosoma brucei histone deacetylase 1 0.0216 0.0444 0.1622
Chlamydia trachomatis DNA ligase 0.0021 0.0015 0.1098
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0029
Trypanosoma cruzi mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Echinococcus multilocularis muscleblind protein 0.0462 0.0981 0.1797
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0013 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0255 0.208
Mycobacterium ulcerans DNA polymerase I 0.0063 0.0108 0.0756
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0062 0.0085
Onchocerca volvulus 0.0018 0.0011 0.001
Plasmodium vivax amine transporter, putative 0.0031 0.0038 0.0139
Schistosoma mansoni amine oxidase 0.0042 0.0062 0.0134
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0016 0.0436
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0255 0.208
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0013 0.0029
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0016 0.0026
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.009 0.0331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Onchocerca volvulus 0.0031 0.0038 0.0038
Leishmania major histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus granulosus hypothetical protein 0.0028 0.0031 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0038 0.0052
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0037 0.005
Brugia malayi Cytochrome P450 family protein 0.0031 0.0039 0.0053
Brugia malayi Serotonin receptor 0.0028 0.0031 0.0042
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0017 0.0482
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0031 0.0056
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.037 1
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0015 0.0033
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0016 0.0034
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0062 0.0229
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus geminin 0.0175 0.0354 0.0763
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0015 0.0009
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0017 0.0063
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0598 0.1279 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0031 0.0066
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0 0.0001
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0017 0.0063
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0013 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0037 0.0123
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0028
Trypanosoma cruzi mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0015 0.0406
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0017 0.0036
Brugia malayi Heterochromatin protein 1 0.0084 0.0154 0.0212
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Brugia malayi CXXC zinc finger family protein 0.0031 0.0038 0.0052
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0131 0.2048
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Plasmodium falciparum importin beta, putative 0.0029 0.0034 0.0123
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2506 0.5458 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Schistosoma mansoni adenoreceptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Trypanosoma cruzi mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0016 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0016 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0016 0.0038
Echinococcus multilocularis sterol regulatory element binding protein 0.0131 0.0256 0.0469
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0031 0.0195
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0037 0.0123
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0004 0.0008
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0095 0.0718
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0018
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0031 0.0066
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0013 0.0006
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0008 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0015 0.0028
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Brugia malayi Importin beta-1 subunit 0.0029 0.0034 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0016 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0062 0.0134
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0016 0.0026
Onchocerca volvulus 0.003 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi Melatonin receptor type 1A 0.0028 0.0031 0.0042
Loa Loa (eye worm) histone deacetylase 11 0.0075 0.0135 0.0856
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0015 0.0033
Echinococcus multilocularis serotonin transporter 0.0182 0.037 0.0677
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0482
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0039 0.0209
Echinococcus multilocularis somatostatin receptor 0.0028 0.0031 0.0056
Echinococcus granulosus fmrfamide receptor 0.0028 0.0031 0.0066
Toxoplasma gondii aldehyde dehydrogenase 0.0188 0.0381 0.1406
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus granulosus Niemann Pick C1 protein 0.0304 0.0636 0.1371
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0021
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0031 0.0066
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0015 0.0247
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0131 0.4479
Wolbachia endosymbiont of Brugia malayi DNA polymerase I 0.0063 0.0108 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0062 0.0134
Schistosoma mansoni topbp1 0.0021 0.0015 0.0032
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0038 0.0082
Plasmodium falciparum histone deacetylase 1 0.0216 0.0444 0.1638
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0131 0.0931
Brugia malayi chromobox protein homolog 3 0.0047 0.0073 0.0101
Echinococcus multilocularis protein patched 0.0131 0.0256 0.0469
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0031 0.0056
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.001
Plasmodium falciparum telomerase reverse transcriptase 0.1251 0.271 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0054 0.0116
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0066
Echinococcus granulosus somatostatin receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0074 0.0472
Echinococcus granulosus sterol regulatory element binding protein 0.0131 0.0256 0.0552
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0062 0.0392
Schistosoma mansoni histone deacetylase 0.0216 0.0444 0.0957
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus granulosus sex peptide receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.037 0.2353
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0284
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0081 0.1355
Echinococcus granulosus allatostatin A receptor 0.0028 0.0031 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Trypanosoma brucei telomerase reverse transcriptase 0.1251 0.271 1
Echinococcus multilocularis protein dispatched 1 0.0149 0.0296 0.0543
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0017 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0021
Echinococcus granulosus single minded 2 0.0047 0.0073 0.0157
Plasmodium falciparum LCCL domain-containing protein 0.0048 0.0074 0.0274
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Brugia malayi nuclear receptor NHR-88 0.0021 0.0015 0.0021
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0031 0.0056
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0031 0.0066
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0031 0.0042
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0031 0.0056
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0154 0.2578
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0031 0.0056
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0214 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0073 0.1223
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0073 0.0131 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0037 0.0135
Brugia malayi protein C24B5.3 0.0018 0.0011 0.0014
Leishmania major protein kinase, putative 0.002 0.0015 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0095 0.0339
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0016 0.0026
Onchocerca volvulus 0.0028 0.0031 0.0031
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0065 0.009
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0015 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus chromobox protein 1 0.0084 0.0154 0.0333
Brugia malayi Muscleblind-like protein 0.0462 0.0981 0.1351
Brugia malayi DKFZp564C0469 protein 0.0021 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0017 0.0036
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0017 0.0061
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0188 0.0381 0.0698
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0017
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0095 0.0604
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0033
Onchocerca volvulus 0.0018 0.0011 0.001
Brugia malayi glutathione reductase 0.0057 0.0095 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0005
Loa Loa (eye worm) intermediate filament protein 0.003 0.0037 0.0232
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.037 0.0509
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.005
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0031 0.0056
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Onchocerca volvulus 0.0028 0.0031 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0066
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0002 0.0004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0095 0.0174
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0004 0.0055
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0038 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0016 0.0026
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0015 0.0232
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0031 0.0066
Schistosoma mansoni DNA polymerase eta 0.0019 0.0013 0.0027
Echinococcus granulosus expressed conserved protein 0.0286 0.0596 0.1284
Echinococcus multilocularis muscleblind protein 1 0.0462 0.0981 0.1797
Echinococcus granulosus tar DNA binding protein 0.0193 0.0393 0.0847
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0016 0.0044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0013 0.0029
Schistosoma mansoni rab6-interacting 0.0048 0.0074 0.016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii DNA polymerase I domain-containing protein 0.0018 0.001 0.0036
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0033
Schistosoma mansoni lipoxygenase 0.0123 0.024 0.0518
Echinococcus granulosus GPCR family 2 0.0016 0.0005 0.001
Onchocerca volvulus 0.0048 0.0074 0.0074
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0101 0.0374
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0028
Brugia malayi AKH receptor 0.0028 0.0031 0.0042
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0004 0.0021
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0013 0.0207
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0031 0.0056
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0013 0.0023
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0062 0.0134
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Leishmania major DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Mycobacterium tuberculosis Possible oxidoreductase 0.0042 0.0062 0.0439
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.009 0.8247
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.032
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Onchocerca volvulus 0.0028 0.0031 0.0031
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0073 0.0131 0.083
Schistosoma mansoni chromobox protein 0.0014 0 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0017 0.0272
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0031 0.0066
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0013 0.0017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0028
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni lamin 0.003 0.0037 0.0079
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0013 0.0037
Brugia malayi hypothetical protein 0.0048 0.0074 0.0102
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis 0.0021 0.0016 0.0029
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0017 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Brugia malayi hypoxia-induced factor 1 0.0182 0.0368 0.0507
Schistosoma mansoni cytochrome P450 0.0021 0.0016 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0016 0.0044
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0031 0.0195
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0038 0.007
Brugia malayi Cytochrome P450 family protein 0.0067 0.0117 0.0161
Onchocerca volvulus 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0285 0.0594 0.3782
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0095 0.035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0051 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0017 0.0272
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0005 0.0006
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0015 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Schistosoma mansoni cpg binding protein 0.0033 0.0042 0.009
Plasmodium vivax histone deacetylase, putative 0.0075 0.0135 0.0496
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0022 0.0067
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0031 0.0056
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0008 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0031 0.0066
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus granulosus snurportin 1 0.031 0.0648 0.1397
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0358
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0004 0.0006
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0031 0.0056
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0016 0.0026
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0039 0.0124
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0062 0.0229
Brugia malayi hypothetical protein 0.0021 0.0015 0.002
Plasmodium vivax 5'-3' exonuclease, N-terminal resolvase-like domain, putative 0.0045 0.0068 0.0251
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Brugia malayi hypothetical protein 0.0031 0.0038 0.0052
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0031 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0073 0.1223
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0031 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0021
Toxoplasma gondii RNA-directed DNA polymerase 0.1251 0.271 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Leishmania major trypanothione reductase 0.0057 0.0095 0.0339
Trypanosoma brucei histone deacetylase, putative 0.0075 0.0135 0.0477
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0462 0.0981 0.6246
Echinococcus multilocularis Polycystic kidney disease protein 0.0048 0.0074 0.0136
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi CHE-14 protein 0.0131 0.0256 0.0352
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0062 0.0439
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Entamoeba histolytica histone deacetylase, putative 0.0216 0.0444 0.6977
Brugia malayi G protein-coupled receptor 0.0028 0.0031 0.0042
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0031 0.0066
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0062 0.0229
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0013 0.0025
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0165 0.0302
Loa Loa (eye worm) hypothetical protein 0.0048 0.0074 0.0472
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0031 0.0056
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0017 0.0048
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Brugia malayi RNA, U transporter 1 0.0083 0.0151 0.0207
Echinococcus granulosus Polycystic kidney disease protein 0.0048 0.0074 0.016
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0031 0.0038 0.3281
Onchocerca volvulus Histone deacetylase 10 homolog 0.0075 0.0135 0.0134
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis cpg binding protein 0.0033 0.0042 0.0077
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0016 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0096
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi hypothetical protein 0.0021 0.0015 0.002
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0016 0.0006 0.0012
Echinococcus multilocularis histone deacetylase 3 0.0216 0.0444 0.0814
Brugia malayi histone deacetylase 3 (HD3) 0.0216 0.0444 0.0611
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0135 0.029
Echinococcus granulosus dna polymerase eta 0.0019 0.0013 0.0027
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0004 0.0009
Schistosoma mansoni loxhd1 0.0048 0.0074 0.016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0108
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0017 0.005
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0031 0.0195
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0154 0.0981
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0016 0.0026
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0017 0.0036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0061
Echinococcus granulosus chromobox protein 2 0.0014 0 0.0001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0054 0.034
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0017 0.004
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0013 0.0207
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0209 0.0428 0.0784
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0232
Onchocerca volvulus Protein patched homolog 0.0018 0.0011 0.001
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0016 0.0026
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0005 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0016 0.0044
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0062 0.0114
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0037 0.0135
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0004 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0131 0.0256 0.1629
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0043 0.0719
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0013 0.0079
Trypanosoma brucei mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Brugia malayi intermediate filament protein 0.003 0.0037 0.005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0013 0.0006
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0015 0.0033
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0008 0.0015
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0011 0.0038
Brugia malayi cytochrome P450 0.0021 0.0016 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Schistosoma mansoni DNA ligase IV 0.0021 0.0015 0.0032
Echinococcus multilocularis chromobox protein 1 0.0084 0.0154 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Toxoplasma gondii histone deacetylase HDAC4 0.0075 0.0135 0.0496
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Leishmania major mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Echinococcus multilocularis serotonin receptor 0.0028 0.0031 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0031 0.0042
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0016 0.0026
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0015 0.0033
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0015 0.0247
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0039 0.0247
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Echinococcus multilocularis nibrin 0.0021 0.0015 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0016 0.0044
Schistosoma mansoni coup transcription factor 0.0021 0.0015 0.0033
Echinococcus multilocularis chromobox protein 1 0.0084 0.0154 0.0283
Echinococcus granulosus Niemann Pick C1 protein 0.0435 0.0922 0.1988
Brugia malayi Doublecortin family protein 0.0048 0.0074 0.0102
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0016 0.0006 0.002
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0017 0.0037
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0017 0.0036
Loa Loa (eye worm) histone deacetylase 0.0075 0.0135 0.0856
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0013 0.022
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0062 0.0134
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0188 0.0381 0.315
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Trichomonas vaginalis ran, putative 0.0021 0.0017 0.0278
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0056
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0015 0.0033
Echinococcus granulosus histone deacetylase 0.0075 0.0135 0.029
Plasmodium vivax glutathione reductase, putative 0.0057 0.0095 0.035
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0016 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0013 0.0037
Plasmodium vivax histone deacetylase 2, putative 0.0075 0.0135 0.0496
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0016 0.0026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Leishmania major histone deacetylase, putative 0.0216 0.0444 0.1628
Schistosoma mansoni topbp1 0.0021 0.0015 0.0032
Schistosoma mansoni histone deacetylase 1 2 3 0.0075 0.0135 0.029
Leishmania major histone deacetylase, putative 0.0075 0.0135 0.0485
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0039 0.0131
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0031 0.0066
Onchocerca volvulus 0.005 0.0081 0.008
Brugia malayi DNA polymerase I family protein 0.0018 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.0014 0 0.0001
Schistosoma mansoni chromobox protein 0.0014 0 0.0001
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0031 0.0066
Echinococcus multilocularis histone deacetylase 1 0.0216 0.0444 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0009 0.0138
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0031 0.0066
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0031 0.0066
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0044 0.0066 0.0244
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0015 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0381 0.0821
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0017 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0131 0.0931
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0213
Echinococcus granulosus muscleblind protein 0.0462 0.0981 0.2114
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Echinococcus granulosus serotonin receptor 0.0028 0.0031 0.0066
Schistosoma mansoni chromobox protein 0.0084 0.0154 0.0333
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0031 0.0066
Echinococcus granulosus nibrin 0.0021 0.0015 0.0032
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0013 0.0029
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0015 0.0033
Onchocerca volvulus 0.0028 0.0031 0.0031
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.009 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0028
Brugia malayi hypothetical protein 0.0147 0.0292 0.0402
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0031 0.0042
Echinococcus granulosus Chromo domain 0.0014 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0008 0.0015
Brugia malayi histone deacetylase 1 (HD1) 0.0216 0.0444 0.0611
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0052
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0016 0.0044
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0004 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0015 0.0043
Onchocerca volvulus 0.0016 0.0006 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0008 0.005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0009
Echinococcus granulosus histone deacetylase 8 0.0075 0.0135 0.029
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0034 0.0103
Schistosoma mansoni histone deacetylase 0.0216 0.0444 0.0957
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1251 0.271 1
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Toxoplasma gondii hypothetical protein 0.0031 0.0038 0.0139
Echinococcus granulosus importin subunit beta 1 0.0029 0.0034 0.0072
Schistosoma mansoni hypothetical protein 0.0034 0.0045 0.0097
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0002 0.0005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.0648 0.4128
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0017 0.0087
Echinococcus granulosus histone deacetylase 6 0.0075 0.0135 0.029
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0209 0.0428 0.0922
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0028
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0016 0.0006 0.002
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Toxoplasma gondii histone deacetylase HDAC3 0.0216 0.0444 0.1638
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0165 0.0355
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Brugia malayi Pre-SET motif family protein 0.0252 0.0522 0.0719
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Brugia malayi G-protein coupled receptor 0.0028 0.0031 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Schistosoma mansoni lipoxygenase 0.0209 0.0428 0.0922
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0015 0.0028
Echinococcus granulosus neuropeptide receptor 0.0028 0.0031 0.0066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.008 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0131 0.2048
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0013 0.0026
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0074 0.0136
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0031 0.0066
Brugia malayi Patched protein homolog 1 0.0018 0.0011 0.0014
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0031 0.0056
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Onchocerca volvulus 0.0149 0.0297 0.0296
Onchocerca volvulus 0.003 0.0037 0.0036
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0 0.0001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0038 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Brugia malayi prolyl 4-hydroxylase 0.0016 0.0006 0.0007
Brugia malayi Uncoordinated protein 44 0.0017 0.0008 0.0011
Echinococcus granulosus lamin dm0 0.003 0.0037 0.0079
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0139
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0117 0.0252
Trypanosoma brucei trypanothione reductase 0.0057 0.0095 0.0331
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0309 0.0647 0.1394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0038 0.024
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.0336
Brugia malayi neuropeptide F receptor 0.0028 0.0031 0.0042
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.037 0.2353
Plasmodium falciparum histone deacetylase, putative 0.0075 0.0135 0.0496
Onchocerca volvulus 0.0028 0.0031 0.0031
Echinococcus granulosus survival motor neuron protein 1 0.0731 0.1571 0.3384
Loa Loa (eye worm) hypothetical protein 0.0462 0.0981 0.6246
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0038 0.0082
Schistosoma mansoni ran 0.0021 0.0017 0.0036
Leishmania major hypothetical protein, conserved 0.0016 0.0006 0.0008
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0074 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0015 0.0247
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0117 0.0742
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0287 0.2351
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0013 0.022
Echinococcus granulosus RUN 0.0048 0.0074 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0108
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Leishmania major histone deacetylase, putative 0.0216 0.0444 0.1628
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0031 0.0056
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Onchocerca volvulus 0.0031 0.0038 0.0038
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0017 0.006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0013 0.0023
Mycobacterium ulcerans hypothetical protein 0.0073 0.0131 0.0931
Echinococcus multilocularis Niemann Pick C1 protein 0.0435 0.0922 0.169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0016 0.0044
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0031 0.0056
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0015 0.0028
Brugia malayi TAR-binding protein 0.0193 0.0393 0.0541
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0038 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0031 0.0066
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0017 0.0267
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0048 0.0802
Onchocerca volvulus 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0022 0.0358
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni hypothetical protein 0.0441 0.0936 0.2017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0096
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.024
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0016 0.0006 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0048 0.0802
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0131 0.2048
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0021
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) oxidoreductase 0.0022 0.0017 0.0108
Mycobacterium leprae putative cytochrome p450 0.0021 0.0016 0.0436
Treponema pallidum DNA ligase (lig) 0.0021 0.0015 0.0045
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0013 0.0194
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Leishmania major importin beta-1 subunit, putative 0.0024 0.0022 0.0067
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0074 0.0136
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0287 1
Trichomonas vaginalis set domain proteins, putative 0.0287 0.0598 1
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0038 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0043 0.0719
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Toxoplasma gondii histone deacetylase HDAC5 0.0075 0.0135 0.0498
Mycobacterium ulcerans dehydrogenase 0.0042 0.0062 0.0392
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Toxoplasma gondii histone deacetylase HDAC1 0.0075 0.0135 0.0496
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0017 0.0061
Onchocerca volvulus 0.0014 0 0.0000000055107
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0016 0.0026
Brugia malayi histone deacetylase 11 0.0075 0.0135 0.0185
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0224
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0108
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0131 0.0931
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0031 0.0042
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0033
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Schistosoma mansoni ran 0.0021 0.0017 0.0036
Plasmodium falciparum 5'-3' exonuclease, N-terminal resolvase-like domain, putative 0.0045 0.0068 0.0251
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0188 0.0381 0.1395
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0051 0.0093
Onchocerca volvulus 0.0037 0.0051 0.0051
Chlamydia trachomatis protoporphyrinogen oxidase 0.0042 0.0062 0.5601
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0015 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.0324
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.008 0.011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0051 0.0186
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0062 0.0392
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0031 0.0056
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus multilocularis dna polymerase eta 0.0019 0.0013 0.0023
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0005
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0031 0.0056
Brugia malayi hypothetical protein 0.0028 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.0045 0.0286
Schistosoma mansoni histone deacetylase hda2 0.0075 0.0135 0.029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0017 0.0056
Brugia malayi hypothetical protein 0.0197 0.0402 0.0553
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0182 0.037 0.2353
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0017 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0096
Onchocerca volvulus 0.0018 0.0011 0.001
Toxoplasma gondii helicase, putative 0.0018 0.001 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0031 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0015 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0013 0.0037
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0017 0.0036
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0016 0.0026
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0154 0.2578
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0002 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0033
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0062 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0028
Echinococcus multilocularis sex peptide receptor 0.0028 0.0031 0.0056
Loa Loa (eye worm) histone deacetylase 1 0.0216 0.0444 0.2827
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0013 0.0037
Giardia lamblia Telomerase catalytic subunit 0.1251 0.271 1
Echinococcus multilocularis musashi 0.003 0.0037 0.0067
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0256 0.428
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0004 0.0008
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0015 0.0055
Echinococcus multilocularis histone deacetylase 8 0.0075 0.0135 0.0247
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0016 0.0058
Echinococcus granulosus dnaJ subfamily B 0.0441 0.0936 0.2017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0013 0.0049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0016 0.0044
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0031 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0007 0.0119
Mycobacterium tuberculosis Probable 5'-3' exonuclease 0.0045 0.0068 0.049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0021
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0017 0.0023
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0135 0.0247
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0013 0.0034
Brugia malayi Telomerase reverse transcriptase 0.3329 0.726 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0031 0.0056
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0287 0.2351
Treponema pallidum DNA polymerase I (polA) 0.0063 0.0108 0.2665
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0016 0.0006 0.0008
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0131 0.0931
Onchocerca volvulus 0.0018 0.0011 0.001
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0051 0.0109
Schistosoma mansoni ap endonuclease 0.0021 0.0017 0.0036
Echinococcus multilocularis histone deacetylase 7 0.0075 0.0135 0.0247
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Brugia malayi hypothetical protein 0.0111 0.0214 0.0294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0381 0.291
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0108
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0017 0.0014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0038 0.007
Brugia malayi hypothetical protein 0.0731 0.1571 0.2163
Schistosoma mansoni hypothetical protein 0.031 0.0648 0.1397
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.027
Loa Loa (eye worm) hypothetical protein 0.0075 0.0135 0.0856
Schistosoma mansoni hypothetical protein 0.0175 0.0354 0.0763
Schistosoma mansoni survival motor neuron protein 0.0149 0.0297 0.0639
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni single-minded 0.0059 0.0099 0.0213
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Brugia malayi CHD4 protein 0.0016 0.0004 0.0005
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0062 0.0229
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0081 0.0081
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0216 0.0444 0.7426
Onchocerca volvulus 0.0028 0.0031 0.0031
Brugia malayi Dopamine receptor 0.0028 0.0031 0.0042
Plasmodium falciparum thioredoxin reductase 0.0057 0.0095 0.035
Brugia malayi SWIRM domain containing protein 0.0042 0.0062 0.0085
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0015 0.0032
Toxoplasma gondii thioredoxin reductase 0.0057 0.0095 0.035
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0017 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0051 0.0109
Toxoplasma gondii patched family protein 0.0018 0.0011 0.0038
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0015 0.0021
Loa Loa (eye worm) RNA binding protein 0.0193 0.0393 0.25
Trichomonas vaginalis histone deacetylase, putative 0.0216 0.0444 0.7426
Onchocerca volvulus 0.0287 0.0598 0.0598
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Echinococcus granulosus histone deacetylase 1 0.0216 0.0444 0.0957
Onchocerca volvulus 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Onchocerca volvulus 0.0022 0.0017 0.0017
Mycobacterium tuberculosis Probable DNA polymerase I PolA 0.0063 0.0108 0.0831
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0037 0.0135
Echinococcus granulosus histone deacetylase 3 0.0216 0.0444 0.0957
Echinococcus granulosus dna polymerase kappa 0.0019 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Leishmania major DNA polymerase eta, putative 0.0019 0.0013 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0013 0.0049
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0031 0.0066
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Echinococcus granulosus orexin receptor type 2 0.0028 0.0031 0.0066
Echinococcus multilocularis dnaJ subfamily B 0.0441 0.0936 0.1714
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0031 0.0042
Schistosoma mansoni cpg binding protein 0.0033 0.0042 0.009
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0062 0.2071
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0013
Loa Loa (eye worm) histone deacetylase 3 0.0216 0.0444 0.2827
Schistosoma mansoni histamine h1 receptor 0.0028 0.0031 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Leishmania major GTP-binding protein, putative 0.0021 0.0017 0.0049
Echinococcus multilocularis Ankyrin 0.0018 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0466
Schistosoma mansoni opsin-like receptor 0.0028 0.0031 0.0066
Schistosoma mansoni hypothetical protein 0.0126 0.0246 0.053
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0015 0.0032
Echinococcus granulosus g protein coupled receptor 0.0028 0.0031 0.0066
Leishmania major telomerase reverse transcriptase, putative 0.1251 0.271 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0046 0.0099
Echinococcus multilocularis histone deacetylase 0.0075 0.0135 0.0247
Trypanosoma cruzi mitochondrial DNA polymerase I protein A, putative 0.0018 0.001 0.0024
Mycobacterium ulcerans 5'-3' exonuclease 0.0045 0.0068 0.044
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0131 0.4479
Loa Loa (eye worm) hypothetical protein 0.0055 0.009 0.0572
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0013 0.0026
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0015 0.0033
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0037 0.0115
Echinococcus granulosus serotonin transporter 0.0182 0.037 0.0797
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0004 0.0025
Brugia malayi Dopamine receptor protein 1 0.0028 0.0031 0.0042
Mycobacterium tuberculosis Probable reductase 0.013 0.0255 0.208
Brugia malayi Patched related family protein 12 0.0018 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0016 0.0006 0.0012
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0034 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Echinococcus multilocularis snurportin 1 0.031 0.0648 0.1188
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0017 0.0063
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0049
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0038 0.007
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Mycobacterium leprae PROBABLE DNA POLYMERASE I POLA 0.0063 0.0108 0.3697
Brugia malayi Dopamine receptor protein 2 0.0028 0.0031 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0015 0.0021
Entamoeba histolytica hypothetical protein 0.0111 0.0214 0.3354
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0013 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0016 0.0257
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0131 0.0179
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0017 0.0032
Echinococcus granulosus chromobox protein 1 0.0084 0.0154 0.0333
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0016 0.0026
Onchocerca volvulus 0.0018 0.0011 0.001
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.0229
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0083 0.0619
Schistosoma mansoni importin beta-1 0.0029 0.0034 0.0072
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0049
Onchocerca volvulus 0.0028 0.0031 0.0031
Trypanosoma brucei histone deacetylase 4 0.0075 0.0135 0.0477
Onchocerca volvulus 0.0031 0.0038 0.0038
Onchocerca volvulus 0.0028 0.0031 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0393 0.0847
Onchocerca volvulus 0.0048 0.0074 0.0074
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0031 0.0042
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0037 0.0135
Echinococcus multilocularis expressed conserved protein 0.0286 0.0596 0.1092
Loa Loa (eye worm) serotonin transporter b 0.0182 0.037 0.2353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0255 0.8878
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0006 0.0035
Echinococcus granulosus lamin 0.003 0.0037 0.0079
Leishmania major hypothetical protein, conserved 0.003 0.0037 0.0123
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0017 0.0256
Schistosoma mansoni hypothetical protein 0.0111 0.0214 0.046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0031 0.0056
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0066
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0031 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0096
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0038 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0031 0.0195
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0017 0.0023
Leishmania major cytochrome p450-like protein 0.0021 0.0016 0.0046
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0017 0.0031
Echinococcus granulosus neuropeptide receptor 0.0028 0.0031 0.0066
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0131 0.102
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0016 0.0026
Echinococcus granulosus Protein patched homolog 1 0.0131 0.0256 0.0552
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0135 0.0485
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0031 0.0056
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0039 0.0131
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0051
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0031 0.0031
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0284
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0017 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.2133 0.4641 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0188 0.0381 0.0821
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0054 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0247
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0017 0.0023
Brugia malayi Patched related family protein 4 0.0018 0.0011 0.0014
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0008 0.0018
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0015 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0081 0.0174
Brugia malayi Myosin head containing protein 0.0018 0.0011 0.0014
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0598 0.1279 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0031 0.0042
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0008 0.0018
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0015 0.0247
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0031 0.0066
Brugia malayi Histone deacetylase family protein 0.0075 0.0135 0.0185
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0031 0.0066
Brugia malayi Serotonin receptor 0.0028 0.0031 0.0042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0031 0.0066
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0038 0.007
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0031 0.0042
Onchocerca volvulus 0.0028 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0015 0.0021
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0017 0.0036
Leishmania major UDP-galactopyranose mutase 0.0042 0.0062 0.0217
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0015 0.0035
Schistosoma mansoni chromobox protein 0.0084 0.0154 0.0333
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0131 0.0469
Schistosoma mansoni intermediate filament proteins 0.003 0.0037 0.0079
Onchocerca volvulus 0.0031 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0016 0.0044
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0031 0.0195
Schistosoma mansoni rab6-interacting 0.0048 0.0074 0.016
Schistosoma mansoni biogenic amine receptor 0.0028 0.0031 0.0066
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0073 0.0073
Schistosoma mansoni neuropeptide receptor 0.0028 0.0031 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.0393 0.25
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0061 0.0132
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0031 0.0056
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0013 0.0027
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0065 0.0416
Onchocerca volvulus 0.0028 0.0031 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0016 0.0044
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0038 0.007
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0082
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Plasmodium vivax patched family protein, putative 0.0018 0.0011 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0004 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0016 0.0044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0033
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0016 0.0046
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0017 0.0022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0031 0.0066
Plasmodium falciparum glutathione reductase 0.0057 0.0095 0.035
Plasmodium vivax multidomain scavenger receptor, putative 0.0048 0.0074 0.0274
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.001
Chlamydia trachomatis DNA polymerase I 0.0063 0.0108 1
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0062 0.0229
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0038 0.0082
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0013 0.0037
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0016 0.0026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0195
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0094
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0034 0.0123
Echinococcus multilocularis lamin 0.003 0.0037 0.0067
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0031 0.0195
Brugia malayi steroid hormone receptor 0.0021 0.0015 0.0021
Schistosoma mansoni amine GPCR 0.0028 0.0031 0.0066
Loa Loa (eye worm) patched family protein 0.0018 0.0011 0.0065
Brugia malayi RE15519p 0.0028 0.0031 0.0042
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0017 0.0041
Brugia malayi Death domain containing protein 0.0017 0.0008 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0017 0.0048
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0051
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0255 0.208
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0013 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0031 0.0066
Echinococcus multilocularis Niemann Pick C1 protein 0.0304 0.0636 0.1166
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.037 0.0797
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0038 0.0082
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.0393 0.0541
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0131 0.0931
Schistosoma mansoni hypothetical protein 0.0175 0.0354 0.0763
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0013 0.0034
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0056
Toxoplasma gondii 5'-3' exonuclease, N-terminal resolvase family domain-containing protein 0.0022 0.0018 0.0066
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0065 0.012
Brugia malayi Patched family protein 0.0018 0.0011 0.0014
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0017 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Schistosoma mansoni ap endonuclease 0.0021 0.0017 0.0036
Echinococcus granulosus cpg binding protein 0.0033 0.0042 0.009
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0016 0.0006 0.002
Leishmania major mitochondrial structure specific endonuclease I (SSE-1), putative 0.0045 0.0068 0.0239
Schistosoma mansoni amine oxidase 0.0042 0.0062 0.0134
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0022 0.0017 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0214 0.046
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0017 0.006
Entamoeba histolytica Ran family GTPase 0.0021 0.0017 0.0261
Brugia malayi sulfakinin receptor protein 0.0028 0.0031 0.0042
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0255 0.208
Schistosoma mansoni netrin receptor unc5 0.0017 0.0008 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0038 0.0052
Brugia malayi Histone deacetylase family protein 0.0075 0.0135 0.0185
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0099 0.0213
Brugia malayi hypothetical protein 0.003 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0395
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0045 0.0062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0036
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0031 0.0195
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0008 0.0018
Brugia malayi hypothetical protein 0.0018 0.0011 0.0014
Schistosoma mansoni hypothetical protein 0.0149 0.0297 0.0639
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.024
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0017 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0031 0.0056
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0287 0.2351
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0004 0.0055

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 25 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) = 25 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) = 102 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
ED50 (functional) = 102 uM kg-1 Ex vivo inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. (i.p.) ChEMBL. 2966246
F (ADMET) = 66 % Oral bioavailability in human ChEMBL. 17870541
F (ADMET) = 66 % Oral bioavailability in human ChEMBL. 17870541
IC50 (functional) = 0.0046 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in synaptosomes from the rat brain cortex ChEMBL. 2966246
IC50 (functional) = 0.08 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in synaptosomes from the rat brain cortex ChEMBL. 2966246
IC50 (functional) = 0.8 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 0.8 uM In vitro inhibition of the accumulation of (-)-[3H]-Norepinephrine in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 2.5 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. ChEMBL. 2966246
IC50 (functional) = 2.5 uM In vitro inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain. ChEMBL. 2966246
Ratio (functional) = 0.058 Selectivity expressed as ratio between NE and 5-HT uptake inhibition in rat synaptosomes ChEMBL. 2966246
Ratio (functional) = 0.32 Selectivity expressed as ratio between NE and 5-HT uptake inhibition in mouse brain slices ChEMBL. 2966246

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 2966246

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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