Detailed information for compound 431142

Basic information

Technical information
  • TDR Targets ID: 431142
  • Name: 5-[(4-bromophenyl)methyl]-2-(phenylsulfanylme thyl)imidazo[4,5-c]pyridine
  • MW: 410.33 | Formula: C20H16BrN3S
  • H donors: 0 H acceptors: 2 LogP: 4.33 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)Cn1ccc2c(c1)nc(n2)CSc1ccccc1
  • InChi: 1S/C20H16BrN3S/c21-16-8-6-15(7-9-16)12-24-11-10-18-19(13-24)23-20(22-18)14-25-17-4-2-1-3-5-17/h1-11,13H,12,14H2
  • InChiKey: MTWGESHKSOCJSY-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 5-[(4-bromophenyl)methyl]-2-[(phenylthio)methyl]imidazo[4,5-c]pyridine
  • 5-(4-bromobenzyl)-2-[(phenylthio)methyl]imidazo[4,5-c]pyridine
  • 5-[(4-bromophenyl)methyl]-2-(phenylsulfanylmethyl)imidazo[5,4-c]pyridine
  • 5-[(4-bromophenyl)methyl]-2-[(phenylthio)methyl]imidazo[5,4-c]pyridine
  • 5-(4-bromobenzyl)-2-[(phenylthio)methyl]imidazo[5,4-c]pyridine
  • 5H-Imidazo[4,5-c]pyridine, 5-[(4-bromophenyl)methyl]-2-[(phenylthio)methyl]-
  • AIDS-415816
  • AIDS415816

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0018 0.0023 0.005
Echinococcus granulosus ryanodine receptor 44f 0.2044 0.6516 0.7945
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0025 0.0038
Echinococcus multilocularis ryanodine receptor 44f 0.2044 0.6516 0.7945
Echinococcus granulosus ran binding protein 9 0.0013 0.0006 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Mycobacterium tuberculosis Possible hydrolase 0.0016 0.0015 0.0114
Onchocerca volvulus 0.0019 0.0025 0.0128
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0035
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0025 0.0753
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.026 0.0797 1
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0025 0.0026
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0363 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0034 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Plasmodium falciparum centrin-1 0.0018 0.0023 0.2165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0085 0.01
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0562 0.1765 0.2708
Onchocerca volvulus Serine\/threonine kinase homolog 0.02 0.0607 0.3642
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0031 0.0063 0.0073
Trypanosoma brucei unspecified product 0.0023 0.0038 0.0095
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.002 0.0098
Echinococcus granulosus potassium large conductance calcium activated 0.0019 0.0025 0.0026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0025 0.0025
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Echinococcus multilocularis dnaJ subfamily B 0.0844 0.2669 0.3253
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0017 0.002 0.0043
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0182 0.5477
Schistosoma mansoni spry domain containing socs box protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0465 0.1455 0.2233
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Entamoeba histolytica MIR domain protein 0.0198 0.0598 0.9859
Trypanosoma cruzi I/6 autoantigen, putative 0.0018 0.0023 0.005
Schistosoma mansoni SPRY domain containing protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) programmed cell death protein 6 0.0018 0.0023 0.0035
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0019 0.0025 0.0022
Loa Loa (eye worm) ctsf protein 0.0018 0.0023 0.0035
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0607 0.1784
Echinococcus granulosus EF HAND 1 calcium binding site 0.0018 0.0023 0.0023
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0025 0.0026
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0023 0.0051
Mycobacterium tuberculosis Probable reductase 0.0084 0.0235 0.29
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0003 0.0003
Echinococcus granulosus ran binding protein 9 0.0013 0.0006 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0016 0.0015 0.0027
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Brugia malayi protein C26E6.5 0.0013 0.0006 0.0002
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0159 0.0475 0.0575
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0025 0.0022
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0902 0.2856 0.2856
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0078 0.2334
Entamoeba histolytica hypothetical protein 0.0013 0.0007 0.0123
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0159 0.0475 0.0575
Echinococcus multilocularis spry domain containing socs box protein 0.0013 0.0006 0.0003
Brugia malayi SPRY domain containing protein 0.0013 0.0006 0.0002
Toxoplasma gondii centrin, putative 0.0018 0.0023 0.068
Echinococcus granulosus deoxyribonuclease 1 0.0207 0.0628 0.0762
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0159 0.0475 0.0575
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0363 0.2168
Echinococcus granulosus calumenin 0.0018 0.0023 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0078 0.0216 0.0332
Brugia malayi Ets-domain containing protein 0.0083 0.023 0.0227
Echinococcus multilocularis alkaline phosphatase 0.0159 0.0475 0.0575
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0081 0.0224
Mycobacterium ulcerans hydrolase 0.0016 0.0015 0.0114
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0194 0.0191
Entamoeba histolytica hypothetical protein 0.0019 0.0025 0.0413
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0079 0.0219 0.0264
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0019 0.0019
Treponema pallidum ribonuclease Z 0.0016 0.0015 0.0413
Schistosoma mansoni ets-related 0.0012 0.0003 0.0003
Echinococcus granulosus smad 0.0017 0.0019 0.0019
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus multilocularis sodium leak channel non selective protein 0.0019 0.0025 0.0026
Entamoeba histolytica hypothetical protein 0.0013 0.0007 0.0123
Entamoeba histolytica hypothetical protein, conserved 0.0018 0.0023 0.0372
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0023
Leishmania major calmodulin-like protein 0.0018 0.0023 0.0074
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0363 0.0363
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Schistosoma mansoni centrin-related 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0019 0.0025 0.0026
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0019 0.0025 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0023 0.1241
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0019 0.0025 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0025 0.0025
Schistosoma mansoni alkaline phosphatase 0.0159 0.0475 0.0475
Brugia malayi ethe1-prov protein 0.0016 0.0015 0.0012
Leishmania major cathepsin L-like protease 0.0018 0.0023 0.0076
Entamoeba histolytica metallo-beta-lactamase family protein 0.0016 0.0015 0.0247
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0016 0.0015 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Loa Loa (eye worm) ryanodine receptor 0.0877 0.2775 0.4258
Onchocerca volvulus 0.0018 0.0023 0.0116
Brugia malayi MGC86306 protein 0.0013 0.0006 0.0002
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0005
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0017 0.002 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0015 0.0114
Echinococcus granulosus ubiquitin specific protease 41 0.0078 0.0216 0.026
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0027 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0235 0.29
Entamoeba histolytica serine/threonine protein kinase, putative 0.02 0.0607 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0006 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Trichomonas vaginalis calcium binding protein, putative 0.0018 0.0023 0.0113
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0072 0.0414
Brugia malayi hypothetical protein 0.0019 0.0025 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0031 0.0027
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0017 0.002 0.002
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0025 0.0026
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0025 0.0022
Echinococcus granulosus programmed cell death protein 0.0018 0.0023 0.0023
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0025 0.0025
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0016 0.0015 0.0023
Schistosoma mansoni ryanodine receptor related 0.3131 1 1
Schistosoma mansoni mitochondrial solute carrier 0.0018 0.0023 0.0023
Brugia malayi ion channel NompC 0.0019 0.0025 0.0022
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0025 0.0026
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0034 0.003
Mycobacterium ulcerans hypothetical protein 0.0016 0.0015 0.0114
Schistosoma mansoni two-pore calcium channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0027 0.0042
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0363 0.9958
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0072 0.1193
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0017 0.002 0.0332
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0006 0.0013
Mycobacterium ulcerans beta lactamase-like protein 0.0016 0.0015 0.0114
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0016 0.0015 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Schistosoma mansoni kinase 0.0102 0.0291 0.0291
Trypanosoma brucei Component of motile flagella 41 0.0018 0.0023 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Echinococcus granulosus E3 ubiquitin protein ligase TRIM9 0.0013 0.0006 0.0003
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0019 0.0025 0.0025
Entamoeba histolytica hypothetical protein 0.0013 0.0006 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0098 0.0115
Echinococcus granulosus voltage gated hydrogen channel 1 0.0019 0.0025 0.0026
Trypanosoma brucei unspecified product 0.0053 0.0133 0.0379
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0016 0.0015 0.0824
Echinococcus granulosus EF hand domain containing family member A2 0.0018 0.0023 0.0023
Onchocerca volvulus 0.0013 0.0006 0.0012
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0019 0.0025 0.0026
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0006 0.0001
Echinococcus granulosus SPRY domain containing protein 0.0013 0.0006 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0381
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0004 0.0063
Echinococcus granulosus expressed protein 0.0366 0.1137 0.1383
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0019 0.0025 0.0026
Brugia malayi Smad1 0.0017 0.0019 0.0015
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0034 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus multilocularis calmodulin 0.0018 0.0023 0.0023
Schistosoma mansoni smad1 5 8 and 0.0017 0.0019 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0363 0.0363
Schistosoma mansoni ran binding protein 9-related 0.0013 0.0006 0.0006
Trichomonas vaginalis mannosyltransferase 1, putative 0.0198 0.0598 0.359
Echinococcus multilocularis deoxyribonuclease 1 2 0.0211 0.064 0.0777
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0023 0.0024
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0155 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0068 0.0182 0.0182
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Echinococcus granulosus centrin 2 0.0018 0.0023 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.0749 0.2364 0.2364
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0025 0.0026
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0016 0.0015 0.0027
Echinococcus multilocularis neuronal calcium sensor 0.0018 0.0023 0.0023
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0078 0.0216 0.3563
Onchocerca volvulus 0.0173 0.0518 0.3106
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0025 0.0025
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0194 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0182 0.0182
Loa Loa (eye worm) transcription factor SMAD2 0.0246 0.0754 0.1158
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0016 0.0015 0.015
Leishmania major arginine N-methyltransferase-like protein 0.0031 0.0063 0.0251
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0015 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0283 0.1684
Leishmania major DNA polymerase eta, putative 0.0058 0.0151 0.0636
Toxoplasma gondii bicoid-interacting protein BIN3 0.0017 0.002 0.0606
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0006 0.0317
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0019 0.0025 0.0025
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0025 0.0026
Echinococcus granulosus ryanodine receptor 44f 0.257 0.82 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0025 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Echinococcus granulosus calmodulin 0.0018 0.0023 0.0023
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0016 0.0015 0.0067
Brugia malayi hypothetical protein 0.0016 0.0015 0.0012
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0019 0.0025 0.0022
Brugia malayi metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.0012
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0019 0.0025 0.0026
Schistosoma mansoni hypothetical protein 0.0844 0.2669 0.2669
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0154 0.044
Echinococcus granulosus protein arginine N methyltransferase 7 0.0017 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0027 0.0027
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0025 0.0025
Echinococcus granulosus sodium leak channel non selective protein 0.0019 0.0025 0.0026
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0018 0.0023 0.0023
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0151 0.043
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0363 0.2168
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0016 0.0015 0.0041
Leishmania major arginine N-methyltransferase, type I 0.0017 0.002 0.0063
Brugia malayi metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.0012
Entamoeba histolytica hypothetical protein 0.0013 0.0007 0.0123
Trichomonas vaginalis myosin light chain 1, putative 0.0018 0.0023 0.0113
Trypanosoma brucei glyoxalase II 0.0016 0.0015 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Brugia malayi EF hand family protein 0.0018 0.0023 0.0019
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0072 1
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0019 0.0025 0.0026
Entamoeba histolytica hypothetical protein 0.0019 0.0025 0.0413
Chlamydia trachomatis ribonuclease Z 0.0016 0.0015 0.1359
Brugia malayi programmed cell death protein 6 0.0018 0.0023 0.0019
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Echinococcus granulosus TRP transient receptor potential channel 0.0019 0.0025 0.0026
Echinococcus granulosus two pore calcium channel protein 2 0.0019 0.0025 0.0026
Schistosoma mansoni smad 0.0017 0.0019 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0023 0.0024
Echinococcus multilocularis chronic lymphocytic leukemia deletion region 0.0013 0.0006 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0083 0.098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0035
Echinococcus granulosus ETHE1 protein 0.0016 0.0015 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0025 0.0026
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0025 0.0026
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0019 0.0025 0.0057
Schistosoma mansoni neuronal calcium sensor 0.0018 0.0023 0.0023
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0025 0.0026
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0034 0.0037
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0098 0.0115
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0146 0.0433 0.0665
Brugia malayi Muscleblind-like protein 0.0146 0.0433 0.043
Onchocerca volvulus 0.0018 0.0023 0.0116
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0025 0.0026
Brugia malayi Carm1-pending protein 0.0017 0.002 0.0017
Trichomonas vaginalis apoptosis inducing factor, putative 0.0019 0.0026 0.0133
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0025 0.0022
Loa Loa (eye worm) FSN-1 protein 0.0013 0.0006 0.0009
Onchocerca volvulus 0.0018 0.0023 0.0113
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0006 0.018
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0025 0.0038
Schistosoma mansoni hypothetical protein 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0019 0.0025 0.0056
Entamoeba histolytica SPRY domain protein 0.0013 0.0006 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1064 0.3375 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0025 0.0046 0.012
Trichomonas vaginalis calcineurin B subunit, putative 0.0018 0.0023 0.0113
Echinococcus granulosus transient receptor potential gamma protein 0.0019 0.0025 0.0026
Echinococcus multilocularis centrin 2 0.0018 0.0023 0.0023
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0034 0.0181
Brugia malayi Cytochrome P450 family protein 0.0025 0.0044 0.004
Schistosoma mansoni cpg binding protein 0.0063 0.0166 0.0166
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.002 0.002
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0016 0.0015 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0128
Echinococcus granulosus SPRY domain containing protein 0.0013 0.0006 0.0003
Echinococcus multilocularis transfer RNA-Gly 0.0019 0.0025 0.0026
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0083 0.023 0.0353
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Onchocerca volvulus 0.0013 0.0006 0.0012
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0016 0.0015 0.0027
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0025 0.0128
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0266 0.3282
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0025 0.0025
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Schistosoma mansoni ets 0.0012 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0031 0.0034
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Plasmodium vivax vivapain-2 0.0018 0.0023 0.1268
Brugia malayi hypothetical protein 0.0079 0.0219 0.0216
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0194 0.056
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.0157
Mycobacterium ulcerans glyoxalase II, GloB 0.0016 0.0015 0.0114
Leishmania major centrin, putative 0.0018 0.0023 0.0074
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0017 0.002 0.002
Echinococcus granulosus calbindin 32 0.0018 0.0023 0.0023
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0079 0.0219 0.0264
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0025 0.0027
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0154 0.1873
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0023 0.0023
Brugia malayi Pre-SET motif family protein 0.0465 0.1455 0.1452
Echinococcus granulosus dna polymerase kappa 0.0059 0.0154 0.0184
Trichomonas vaginalis calcineurin B subunit, putative 0.0018 0.0023 0.0113
Trypanosoma cruzi calmodulin, putative 0.0018 0.0023 0.005
Brugia malayi SPRY domain containing protein 0.0013 0.0006 0.0002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0025 0.0025
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0025 0.0128
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0006 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0266 0.3282
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0017 0.002 0.0043
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0025 0.0025
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.02 0.0607 0.0736
Echinococcus granulosus serine:threonine protein kinase PLK1 0.02 0.0607 0.0736
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0048 0.0118 0.0334
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0023 0.0024
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0025 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.002 0.002
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0235 0.29
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0072 0.1105
Brugia malayi PXA domain containing protein 0.0019 0.0025 0.0022
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0016 0.0015 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0025 0.0027
Trypanosoma cruzi glyoxalase II 0.0016 0.0015 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.002 0.002
Echinococcus multilocularis shaker cognate 0.0019 0.0025 0.0026
Brugia malayi MH1 domain containing protein 0.0017 0.0019 0.0015
Brugia malayi MIR domain containing protein 0.0198 0.0598 0.0595
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0034 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0023 0.0116
Echinococcus multilocularis ATP dependent RNA helicase Ddx1 0.0013 0.0006 0.0003
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0235 0.29
Brugia malayi Fli-1 protein 0.0251 0.077 0.0767
Brugia malayi SPRY domain containing protein 0.0013 0.0006 0.0002
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0363 0.0557
Schistosoma mansoni calmodulin related calcium binding protein 0.0018 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Schistosoma mansoni transient receptor potential channel 4 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0013 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0173 0.0518 0.0795
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0363 0.5979
Echinococcus granulosus cpg binding protein 0.0063 0.0166 0.0198
Schistosoma mansoni zinc phosphodiesterase 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma brucei beta lactamase 0.0125 0.0364 0.1064
Entamoeba histolytica calcium binding family protein 0.0018 0.0023 0.0372
Plasmodium vivax DEAD/DEAH box ATP-dependent RNA helicase, putative 0.0013 0.0006 0.0317
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0083 0.4584
Echinococcus granulosus alkaline phosphatase 0.0159 0.0475 0.0575
Leishmania major hypothetical protein, conserved 0.0016 0.0015 0.0041
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0019 0.0025 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0072 1
Echinococcus multilocularis set1:ash2 histone methyltransferase complex 0.0013 0.0006 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0154 0.0908
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0023 0.0035
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Trypanosoma brucei centrin, putative 0.0018 0.0023 0.005
Mycobacterium tuberculosis Conserved protein 0.0016 0.0015 0.0114
Schistosoma mansoni DNA helicase recq5 0.0022 0.0034 0.0034
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0019 0.0029
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.002 0.0098
Schistosoma mansoni elf1 0.0012 0.0003 0.0003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0003
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0003 0.0005
Echinococcus multilocularis dna polymerase eta 0.0058 0.0151 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0025 0.0753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Brugia malayi CXXC zinc finger family protein 0.0059 0.0155 0.0151
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0025 0.0753
Schistosoma mansoni neuronal calcium sensor 0.0018 0.0023 0.0023
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0074
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0025 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0133 0.0379
Echinococcus granulosus protein arginine methyltransferase 0.0031 0.0063 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0216 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0025 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0071 0.1166
Brugia malayi ATP-dependent helicase DDX1 0.0013 0.0006 0.0002
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0025 0.0026
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0072 0.8574
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0025 0.0038
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0023 0.2228
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0025 0.0026
Toxoplasma gondii troponin c, isotype gamma, putative 0.0018 0.0023 0.068
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0006 0.0328
Entamoeba histolytica calmodulin, putative 0.0018 0.0023 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0113
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0006 0.0001
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0019 0.0025 0.0022
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0025 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Echinococcus multilocularis calbindin 32 0.0018 0.0023 0.0023
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0019 0.0025 0.0022
Leishmania major cathepsin L-like protease 0.0018 0.0023 0.0076
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0018 0.0023 0.0113
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Brugia malayi Transient-receptor-potential like protein 0.0019 0.0025 0.0022
Schistosoma mansoni zinc phosphodiesterase 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0133 0.0391 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Echinococcus multilocularis expressed protein 0.0366 0.1137 0.1383
Trichomonas vaginalis helicase, putative 0.0013 0.0008 0.0024
Entamoeba histolytica hypothetical protein 0.0013 0.0006 0.0095
Trichomonas vaginalis calcium binding protein, putative 0.0018 0.0023 0.0113
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0025 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0083 0.0231
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0216 0.026
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0025 0.0038
Entamoeba histolytica type A flavoprotein, putative 0.0016 0.0015 0.0247
Onchocerca volvulus 0.0018 0.0023 0.0116
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0363 0.2168
Echinococcus multilocularis E3 ubiquitin protein ligase TRIM9 0.0013 0.0006 0.0003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0216 0.0625
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0182 0.0218
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Echinococcus multilocularis deoxyribonuclease 0.0207 0.0628 0.0762
Echinococcus multilocularis ran binding protein 9 0.0013 0.0006 0.0003
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0027 0.0024
Schistosoma mansoni trithorax protein ash2 0.0013 0.0006 0.0006
Toxoplasma gondii centrin 0.0018 0.0023 0.068
Loa Loa (eye worm) hypothetical protein 0.0058 0.0151 0.0231
Schistosoma mansoni eyes absent homolog 0.0101 0.0288 0.0288
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0018 0.0023 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0266 0.3282
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0151 0.043
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0154 0.044
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0016 0.0015 0.0067
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0363 0.106
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0019 0.0025 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Echinococcus multilocularis two pore calcium channel protein 2 0.0019 0.0025 0.0026
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0018 0.0023 0.0113
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0006 0.0328
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0025 0.0025
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0063 0.0063
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0159 0.0475 0.0575
Schistosoma mansoni deoxyribonuclease 1 related 0.0207 0.0628 0.0628
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.002
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0019 0.0025 0.0026
Brugia malayi Protein arginine N-methyltransferase 0.0017 0.002 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0283 0.1684
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0003 0.0005
Plasmodium vivax unspecified product 0.0016 0.0015 0.0824
Onchocerca volvulus 0.0018 0.0023 0.0113
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0216 0.026
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0025 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0006 0.0317
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0025 0.0025
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0023 0.0116
Schistosoma mansoni reticulocalbin 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0001
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0198 0.0598 0.0598
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0235 0.29
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0216 0.1282
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0034 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0027 0.0027
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0433 0.0524
Plasmodium vivax centrin-1, putative 0.0018 0.0023 0.1241
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0154 0.0908
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0182 0.0182
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0031 0.0063 0.1894
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0381
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0025 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0027 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0025 0.0026
Onchocerca volvulus Huntingtin homolog 0.0133 0.0391 0.2337
Echinococcus multilocularis ubiquitin specific protease 41 0.0078 0.0216 0.026
Mycobacterium ulcerans hydrolase 0.0016 0.0015 0.0114
Schistosoma mansoni tripartite motif protein trim9 0.0013 0.0006 0.0006
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0019 0.0025 0.0056
Leishmania major metallo-beta-lactamase family-like protein 0.0016 0.0015 0.0041
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0071 0.0071
Echinococcus multilocularis transient receptor potential gamma protein 0.0019 0.0025 0.0026
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0016 0.0015 0.0027
Echinococcus multilocularis ran binding protein 9 0.0013 0.0006 0.0003
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0034 0.0181
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0025 0.0026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Brugia malayi glutathione reductase 0.0037 0.0083 0.008
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Toxoplasma gondii SPRY domain-containing protein 0.0013 0.0006 0.0174
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.0016 0.0015 1
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0016 0.0015 0.0027
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0004 0.0001
Echinococcus granulosus hypothetical protein 0.0019 0.0025 0.0026
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0071 0.0067
Loa Loa (eye worm) ryanodine receptor 0.1283 0.4075 0.6255
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0016 0.0015 0.0451
Echinococcus granulosus calpain A 0.0018 0.0023 0.0023
Echinococcus multilocularis neurocalcin 0.0018 0.0023 0.0023
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0154 0.044
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0019 0.0025 0.0026
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Leishmania major centrin, putative 0.0018 0.0023 0.0074
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0025 0.0026
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0017 0.002 0.0606
Leishmania major calmodulin-like protein 0.0018 0.0023 0.0074
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0025 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0607 0.0607
Schistosoma mansoni rab 0.0018 0.0023 0.0023
Echinococcus granulosus bloom syndrome protein 0.0022 0.0034 0.0037
Brugia malayi SPRY domain-containing SOCS box protein SSB-4 0.0013 0.0006 0.0002
Schistosoma mansoni transient receptor potential channel 0.0019 0.0025 0.0025
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0072 0.3975
Trichomonas vaginalis centrin, putative 0.0018 0.0023 0.0113
Mycobacterium ulcerans lipoprotein LpqF 0.0125 0.0364 0.453
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0078 0.0216 0.0216
Trypanosoma cruzi I/6 autoantigen, putative 0.0018 0.0023 0.005
Entamoeba histolytica alkyl sulfatase, putative 0.0016 0.0015 0.0247
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0025 0.0026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0025 0.0753
Mycobacterium tuberculosis Beta lactamase like protein 0.0016 0.0015 0.0114
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0008 0.0024
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Schistosoma mansoni voltage-dependent calcium channel 0.0019 0.0025 0.0025
Echinococcus granulosus EF hand domain containing family member A2 0.0018 0.0023 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Leishmania major hypothetical protein, conserved 0.0025 0.0046 0.0178
Schistosoma mansoni tsg101-related 0.0066 0.0177 0.0177
Brugia malayi olfactory channel protein osm-9 0.0019 0.0025 0.0022
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0025 0.0038
Trypanosoma brucei polo-like protein kinase 0.02 0.0607 0.1784
Giardia lamblia DINP protein human, muc B family 0.0039 0.0091 0.1422
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0072 0.8574
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0023
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0006
Echinococcus multilocularis cpg binding protein 0.0063 0.0166 0.0198
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.026 0.0797 1
Echinococcus multilocularis ryanodine receptor 44f 0.257 0.82 1
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0187 0.0537
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0023 0.0116
Entamoeba histolytica alkyl sulfatase, putative 0.0016 0.0015 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0607 0.3642
Toxoplasma gondii calmodulin CAM1 0.0018 0.0023 0.068
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.02 0.0607 0.0931
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0019 0.0025 0.0022
Brugia malayi cathepsin L-like precursor 0.0012 0.0004 0.0001
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1064 0.3375 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0031 0.0034
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0025 0.0025
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Trichomonas vaginalis A-type flavoprotein 0.0016 0.0015 0.0067
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0019 0.0025 0.0022
Schistosoma mansoni transient receptor potential channel 0.0019 0.0025 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0018 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0007 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0332 1
Loa Loa (eye worm) SPRY domain-containing protein 0.0013 0.0006 0.0009
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0016 0.0015 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0167 0.048
Schistosoma mansoni ran binding protein 9-related 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0035
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Onchocerca volvulus 0.0018 0.0023 0.0116
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0025 0.0026
Toxoplasma gondii hypothetical protein 0.0019 0.0025 0.0753
Schistosoma mansoni ef hand domain family member A2 0.0018 0.0023 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0025 0.0753
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0071 0.0109
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0006 0.0001
Loa Loa (eye worm) glutathione reductase 0.0037 0.0083 0.0128
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0025 0.0026
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0034 0.3604
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0034 0.0037
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0216 0.1282
Onchocerca volvulus 0.0529 0.166 1
Brugia malayi 6-phosphofructokinase 0.0124 0.0363 0.036
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Onchocerca volvulus Putative hydrolase PNKD 0.0016 0.0015 0.0067
Schistosoma mansoni smad1 5 8 and 0.0017 0.0019 0.0019
Echinococcus granulosus neuronal calcium sensor 0.0018 0.0023 0.0023
Echinococcus multilocularis SPRY domain containing protein 0.0013 0.0006 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Echinococcus multilocularis calmodulin 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0072 0.2178
Trypanosoma cruzi SPRY domain/Ankyrin repeats (3 copies), putative 0.0013 0.0006 0.000000026494
Brugia malayi calcium-binding protein 0.0018 0.0023 0.0019
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0018 0.0023 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0023 0.0076
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0025 0.0026
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0025 0.0026
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0025 0.0026
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0085 0.01
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0025 0.0027
Plasmodium falciparum thioredoxin reductase 0.0037 0.0083 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0018 0.0554
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0025 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Echinococcus multilocularis potassium large conductance calcium activated 0.0019 0.0025 0.0026
Schistosoma mansoni gabp alpha 0.0083 0.023 0.023
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0034 0.0037
Schistosoma mansoni centrin 0.0018 0.0023 0.0023
Echinococcus granulosus neurocalcin 0.0018 0.0023 0.0023
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0359 0.1117 0.1117
Echinococcus granulosus dna polymerase eta 0.0058 0.0151 0.018
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0016 0.0015 0.0014
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0019 0.0025 0.1356
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Leishmania major calmodulin, putative 0.0018 0.0023 0.0074
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0023 0.0023
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Echinococcus multilocularis SPRY domain containing protein 0.0013 0.0006 0.0003
Schistosoma mansoni cpg binding protein 0.0063 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0013 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0071 0.0819
Plasmodium vivax SET domain protein, putative 0.0068 0.0182 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0034 0.0181
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0216 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0007 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0063 0.0357
Entamoeba histolytica hypothetical protein 0.0048 0.0118 0.1948
Echinococcus granulosus cathepsin l1 0.0018 0.0023 0.0024
Onchocerca volvulus 0.0198 0.0598 0.359
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0025 0.0046 0.012
Echinococcus multilocularis stromal cell derived factor 2 0.0198 0.0598 0.0726
Onchocerca volvulus 0.0018 0.0023 0.0116
Loa Loa (eye worm) hypothetical protein 0.0538 0.169 0.2594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Plasmodium vivax vivapain-2 0.0018 0.0023 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0034 0.1016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0078 0.0213
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0363 0.5979
Schistosoma mansoni protein arginine n-methyltransferase 0.0017 0.002 0.002
Onchocerca volvulus 0.0059 0.0155 0.0911
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0003 0.0005
Trypanosoma brucei calmodulin, putative 0.0018 0.0023 0.005
Entamoeba histolytica type A flavoprotein, putative 0.0016 0.0015 0.0247
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0194 0.0233
Toxoplasma gondii EFHC1, putative 0.0018 0.0023 0.068
Entamoeba histolytica metallo-beta-lactamase family protein 0.0016 0.0015 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0019 0.0025 0.0026
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0363 0.0439
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0016 0.0015 0.0012
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0025 0.0027
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0072 0.1995
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.0247
Leishmania major calmodulin, putative 0.0018 0.0023 0.0074
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Echinococcus multilocularis ETHE1 protein 0.0016 0.0015 0.0014
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0078 0.0216 0.3499
Echinococcus granulosus intestinal type alkaline phosphatase 0.0159 0.0475 0.0575
Mycobacterium ulcerans hydrolase 0.0016 0.0015 0.0114
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0363 0.4511
Schistosoma mansoni tsg101-related 0.0054 0.0138 0.0138
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0025 0.0027
Schistosoma mansoni hypothetical protein 0.0019 0.0025 0.0025
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0034 0.0463
Schistosoma mansoni DNA polymerase eta 0.0058 0.0151 0.0151
Echinococcus multilocularis calcium uptake protein 1 0.0018 0.0023 0.0023
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Loa Loa (eye worm) hypothetical protein 0.2044 0.6516 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0025 0.0025
Echinococcus granulosus calcium activated potassium channel 0.0019 0.0027 0.0029
Trichomonas vaginalis calmodulin-2, putative 0.0018 0.0023 0.0113
Echinococcus multilocularis EF hand domain containing family member A2 0.0018 0.0023 0.0023
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Schistosoma mansoni neuronal calcium sensor 0.0018 0.0023 0.0023
Echinococcus granulosus chronic lymphocytic leukemia deletion region 0.0013 0.0006 0.0003
Trypanosoma brucei mitochondrial calcium uptake 1 0.0018 0.0023 0.005
Brugia malayi MH1 domain containing protein 0.0017 0.0019 0.0015
Brugia malayi EF hand family protein 0.0018 0.0023 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0235 0.29
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0019 0.0025 0.0025
Mycobacterium ulcerans hypothetical protein 0.0016 0.0015 0.0114
Echinococcus multilocularis zinc phosphodiesterase 0.0016 0.0015 0.0014
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0016 0.0015 0.0014
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0016 0.0015 0.0451
Loa Loa (eye worm) hypothetical protein 0.0079 0.0219 0.0337
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0025 0.0027
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0025 0.0128
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0034 0.003
Echinococcus granulosus two pore calcium channel protein 1 0.0019 0.0025 0.0026
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0216 0.026
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0025 0.0027
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0194 0.3203
Brugia malayi hypothetical protein 0.0173 0.0518 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Echinococcus granulosus zinc phosphodiesterase 0.0016 0.0015 0.0014
Entamoeba histolytica hypothetical protein 0.0019 0.0025 0.0413
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0023 0.0035
Echinococcus multilocularis deoxyribonuclease 0.0207 0.0628 0.0762
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0017 0.002 0.0606
Trichomonas vaginalis set domain proteins, putative 0.0529 0.166 1
Onchocerca volvulus 0.0018 0.0023 0.0116
Plasmodium falciparum thioredoxin reductase 0.0013 0.0006 0.0026
Trypanosoma cruzi glyoxalase II 0.0016 0.0015 0.0027
Giardia lamblia Hypothetical protein 0.0018 0.0023 0.0277
Leishmania major DNA polymerase kappa, putative 0.0039 0.0091 0.0376
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0154 0.0184
Entamoeba histolytica grainin, putative 0.0018 0.0023 0.0372
Loa Loa (eye worm) RecQ helicase 0.0022 0.0034 0.0052
Toxoplasma gondii EF hand domain-containing protein 0.0018 0.0023 0.068
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0034 0.0052
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0235 0.631
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.0247
Loa Loa (eye worm) hypothetical protein 0.0068 0.0182 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Echinococcus multilocularis calpain A 0.0018 0.0023 0.0023
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.002 0.002
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0017 0.002 0.002
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Mycobacterium ulcerans Zn-dependent glyoxylase 0.0016 0.0015 0.0114
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0018 0.0023 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Onchocerca volvulus 0.0068 0.0182 0.1076
Brugia malayi cation channel family protein 0.1262 0.4008 0.4006
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0072 0.0414
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0025 0.0025
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0078 0.0216 0.0216
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0025 0.0026
Echinococcus granulosus cathepsin l1 0.0012 0.0004 0.0001
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0194 0.0828
Entamoeba histolytica hypothetical protein 0.0013 0.0007 0.0123
Trichomonas vaginalis calcium binding protein, putative 0.0018 0.0023 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Leishmania major centrin, putative,caltractin, putative 0.0018 0.0023 0.0074
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0016 0.0015 0.0015
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0072 0.2178
Echinococcus granulosus GA binding protein alpha chain 0.0083 0.023 0.0277
Loa Loa (eye worm) fibroinase 0.0018 0.0023 0.0035
Plasmodium falciparum ATP-dependent RNA helicase DDX1, putative 0.0013 0.0006 0.000000007695
Echinococcus granulosus Solute carrier family 22 5 0.1123 0.3564 0.4344
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0006 0.0003
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0159 0.0475 0.0575
Echinococcus multilocularis muscleblind protein 0.0146 0.0433 0.0524
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0025 0.0025
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0023 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Leishmania major trypanothione reductase 0.0037 0.0083 0.0341
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0381
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Plasmodium vivax glutathione reductase, putative 0.0037 0.0083 0.4584
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Trypanosoma brucei centrin-3 0.0018 0.0023 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0363 0.2168
Brugia malayi Cathepsin L-like precursor 0.0012 0.0004 0.0001
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0034 0.0037
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0363 0.1568
Brugia malayi MH2 domain containing protein 0.0246 0.0754 0.0751
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0006
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0091 0.108
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0025 0.0022
Loa Loa (eye worm) MIR domain-containing protein 0.0198 0.0598 0.0918
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.02 0.0607 0.264
Schistosoma mansoni DNA helicase recq1 0.0022 0.0034 0.0034
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Echinococcus multilocularis two pore calcium channel protein 1 0.0019 0.0025 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0025 0.0026
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0083 0.0128
Trypanosoma brucei I/6 autoantigen 0.0018 0.0023 0.005
Brugia malayi PXA domain containing protein 0.0019 0.0025 0.0022
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0194 0.056
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0044 0.0067
Schistosoma mansoni tsg101-related 0.0066 0.0177 0.0177
Brugia malayi phosphofructokinase 0.0124 0.0363 0.036
Echinococcus granulosus microtubule associated protein 2 0.0749 0.2364 0.288
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0054 0.0138 0.2275
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Echinococcus granulosus dnaJ subfamily B 0.0844 0.2669 0.3253
Echinococcus multilocularis deoxyribonuclease 1 2 0.0207 0.0628 0.0762
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0125 0.0364 1
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0006 0.018
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0025 0.0128
Brugia malayi RE37682p 0.0013 0.0006 0.0002
Brugia malayi Thioredoxin reductase 0.0037 0.0083 0.008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0034 0.1016
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0063 0.0357
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0025 0.0026
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0025 0.0026
Echinococcus multilocularis programmed cell death protein 0.0018 0.0023 0.0023
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0027 0.0029
Leishmania major cathepsin L-like protease 0.0069 0.0187 0.0794
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.0025 0.0038
Echinococcus multilocularis Smad4 0.0017 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.017 0.0203
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0052
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0017 0.002 0.0063
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0006 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0023 0.0116
Echinococcus granulosus protein arginine N methyltransferase 8 0.0031 0.0063 0.0073
Trypanosoma brucei unspecified product 0.0023 0.0038 0.0095
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Trypanosoma cruzi calmodulin, putative 0.0018 0.0023 0.005
Trichomonas vaginalis hypothetical protein 0.0039 0.0089 0.0514
Brugia malayi 6-phosphofructokinase 0.0124 0.0363 0.036
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0018 0.0023 0.0023
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0363 0.0557
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0016 0.0015 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0025 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.0182 0.0218
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0025 0.0025
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0071 0.0082
Echinococcus granulosus deoxyribonuclease 1 0.0207 0.0628 0.0762
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0341 0.1057 0.1057
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0031 0.0048
Leishmania major metallo-beta-lactamase family protein-like protein 0.0016 0.0015 0.0041
Leishmania major programmed cell death 6 protein-like protein 0.0018 0.0023 0.0074
Loa Loa (eye worm) ATP-dependent helicase DDX1 0.0013 0.0006 0.0009
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0034 0.0557
Schistosoma mansoni Smad4 0.0017 0.0019 0.0019
Trichomonas vaginalis centrin, putative 0.0018 0.0023 0.0113
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0019 0.0025 0.0026
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0018 0.0023 0.0372
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0006
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0016 0.0015 0.0023
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0018 0.0023 0.005
Loa Loa (eye worm) hypothetical protein 0.0101 0.0288 0.0441
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Brugia malayi voltage-dependent calcium channel 0.0019 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0009
Toxoplasma gondii calcium-dependent protein kinase 0.0019 0.0025 0.0743
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0124
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0074
Trypanosoma brucei SPRY domain/Ankyrin repeats (3 copies), putative 0.0013 0.0006 0.000000026494
Entamoeba histolytica grainin 2 0.0018 0.0023 0.0372
Loa Loa (eye worm) SPRY domain-containing protein 0.0013 0.0006 0.0009
Brugia malayi Calmodulin-like protein 0.0018 0.0023 0.0019
Brugia malayi Cathepsin L-like precursor 0.0012 0.0004 0.0001
Entamoeba histolytica calmodulin, putative 0.0018 0.0023 0.0372
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0091 0.0376
Echinococcus granulosus Smad4 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0013 0.0006 0.0012
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0023 0.0024
Schistosoma mansoni transient receptor potential channel 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0016 0.0015 0.0027
Echinococcus multilocularis microtubule associated protein 2 0.0749 0.2364 0.288
Echinococcus granulosus set1:ash2 histone methyltransferase complex 0.0013 0.0006 0.0003
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0154 0.1873
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0017 0.002 0.0043
Echinococcus granulosus SPRY domain containing protein 0.0013 0.0006 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0006 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0025 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0187 0.0537
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0015 0.0114
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0363 0.106
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0187 0.0537
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Loa Loa (eye worm) cysteine protease 0.0018 0.0023 0.0035
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0072 0.3975
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0006 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0151 0.0147
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0063 0.0357
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0027 0.0042
Leishmania major cathepsin L-like protease 0.0018 0.0023 0.0076
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0072 0.2178
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0019 0.0025 0.0026
Entamoeba histolytica metallo-beta-lactamase family protein 0.0016 0.0015 0.0247
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Loa Loa (eye worm) MH2 domain-containing protein 0.0246 0.0754 0.1158
Trichomonas vaginalis calcium binding proteins, putative 0.0018 0.0023 0.0113
Loa Loa (eye worm) calmodulin-like protein 0.0018 0.0023 0.0035
Schistosoma mansoni alkaline phosphatase 0.0159 0.0475 0.0475
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0023
Schistosoma mansoni neuronal calcium sensor 0.0018 0.0023 0.0023
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0016 0.0015 0.0041
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0048 0.0118 0.1948
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Echinococcus granulosus SPRY domain containing SOCS box protein 3 0.0013 0.0006 0.0003
Loa Loa (eye worm) EF hand family protein 0.0018 0.0023 0.0035
Mycobacterium tuberculosis Conserved protein 0.0016 0.0015 0.0114
Schistosoma mansoni hypothetical protein 0.0083 0.023 0.023
Plasmodium falciparum cytosolic glyoxalase II 0.0016 0.0015 0.1187
Schistosoma mansoni vesicular amine transporter 0.0019 0.0025 0.0025
Echinococcus granulosus deoxyribonuclease 1 0.0207 0.0628 0.0762
Echinococcus multilocularis cysteine protease 0.0018 0.0023 0.0024
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0018 0.0023 0.005
Echinococcus multilocularis smad 0.0017 0.0019 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0139 0.0396
Treponema pallidum NADH oxidase 0.0013 0.0006 0.0165
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0048 0.0118 0.0334
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.0182 0.0218
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Trichomonas vaginalis calcium binding protein, putative 0.0018 0.0023 0.0113
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Brugia malayi serine/threonine-protein kinase plk-2 0.02 0.0607 0.0604
Brugia malayi hypothetical protein 0.0019 0.0025 0.0022
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0048 0.0118 0.0181
Leishmania major phospholipase c-like protein 0.0018 0.0023 0.0074
Echinococcus granulosus ATP dependent RNA helicase Ddx1 0.0013 0.0006 0.0003
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0023 0.2228
Loa Loa (eye worm) fli-1 protein 0.0251 0.077 0.1182
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0363 0.4511
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Toxoplasma gondii thioredoxin reductase 0.0037 0.0083 0.2511
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Leishmania major DNA polymerase eta, putative 0.0035 0.0078 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0007 0.0005
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0019 0.0025 0.0022
Trypanosoma cruzi centrin, putative 0.0018 0.0023 0.005
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0607 0.1784
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0019 0.0026 0.0133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0015 0.0114
Echinococcus multilocularis EF hand domain containing family member A2 0.0018 0.0023 0.0023
Schistosoma mansoni reticulocalbin 0.0018 0.0023 0.0023
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0025 0.0026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Brugia malayi SPRY domain containing protein 0.0013 0.0006 0.0002
Brugia malayi polk-prov protein 0.0036 0.0081 0.0078
Loa Loa (eye worm) calcium channel 0.0019 0.0025 0.0038
Mycobacterium tuberculosis Conserved protein 0.0016 0.0015 0.0114
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0019 0.0025 0.0022
Brugia malayi cation channel family protein 0.0019 0.0025 0.0022
Echinococcus multilocularis protein arginine methyltransferase 0.0031 0.0063 0.0073
Schistosoma mansoni voltage-gated ion channel 0.0019 0.0025 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0154 0.044
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0071 0.0192 0.0294
Schistosoma mansoni voltage-gated cation channel 0.0019 0.0025 0.0025
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0216 0.0625
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0078 0.0216 0.0213
Trypanosoma cruzi caltractin, putative 0.0018 0.0023 0.005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0216 0.0625
Schistosoma mansoni calmodulin 0.0018 0.0023 0.0023
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0025 0.0025
Brugia malayi MH2 domain containing protein 0.0017 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0359 0.1117 0.1714
Brugia malayi hypothetical protein 0.0019 0.0025 0.0022
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0363 0.5979
Loa Loa (eye worm) voltage-gated calcium channel 0.0019 0.0025 0.0038
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0063 0.0063
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0025 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0154 0.044
Brugia malayi Pre-SET motif family protein 0.0068 0.0182 0.0179
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0017 0.002 0.0031
Loa Loa (eye worm) Smad1 0.0017 0.0019 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0007 0.0005
Loa Loa (eye worm) Carm1-pending protein 0.0017 0.002 0.0031
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0034 0.3604
Loa Loa (eye worm) SPRY domain-containing SOCS box protein SSB-4 0.0013 0.0006 0.0009
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0019 0.0025 0.0056
Leishmania major protein kinase, putative 0.0019 0.0025 0.0083
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0025 0.0027
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0019 0.0025 0.0057
Onchocerca volvulus Huntingtin homolog 0.0133 0.0391 0.2337
Brugia malayi SPRY domain containing protein 0.0013 0.0006 0.0002
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0017 0.002 0.0043
Trypanosoma cruzi centrin-3 0.0018 0.0023 0.005
Toxoplasma gondii cathepsin CPL 0.0018 0.0023 0.0695
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0031 0.0063 0.3459
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0363 0.0557
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0113
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0023 0.0116
Leishmania major calcineurin B subunit, putative 0.0018 0.0023 0.0074
Echinococcus granulosus methyltransferase protein 5 0.0017 0.002 0.002
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0025 0.0025
Echinococcus multilocularis GA binding protein alpha chain 0.0083 0.023 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0019 0.0025 0.0026
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0025 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Brugia malayi hypothetical protein 0.0101 0.0288 0.0284
Echinococcus granulosus sodium channel protein 0.0019 0.0025 0.0026
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0019 0.0019
Schistosoma mansoni smad1 5 8 and 0.0017 0.0019 0.0019
Schistosoma mansoni tripartite motif protein trim9 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0182 0.0182
Onchocerca volvulus 0.0018 0.0023 0.0113
Echinococcus multilocularis calcium activated potassium channel 0.0019 0.0027 0.0029
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0025 0.0026
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0125 0.0364 0.453
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0016 0.0015 0.0023
Leishmania major cathepsin L-like protease 0.0069 0.0187 0.0794
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Trypanosoma cruzi calmodulin, putative 0.0018 0.0023 0.005
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0025 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0024
Mycobacterium ulcerans hypothetical protein 0.0016 0.0015 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.0157
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0025 0.0026
Plasmodium falciparum glutathione reductase 0.0013 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Plasmodium falciparum glutathione reductase 0.0037 0.0083 1
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0018 0.0023 0.0023
Echinococcus multilocularis programmed cell death protein 0.0018 0.0023 0.0023
Entamoeba histolytica calcium-binding protein, putative 0.0018 0.0023 0.0372
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0025 0.0026
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0048 0.0118 0.0334
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0026
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0019 0.0025 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0015 0.0067
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0019 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0081 0.0224
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0025 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0116
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0006 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0025 0.0025
Echinococcus multilocularis cysteine protease 0.0018 0.0023 0.0024
Brugia malayi MH2 domain containing protein 0.0017 0.0019 0.0015
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0018 0.0023 0.0023
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0019 0.0025 0.0022
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0006 0.0026
Brugia malayi Cathepsin L-like precursor 0.0018 0.0023 0.002
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.002 0.0098
Schistosoma mansoni cpg binding protein 0.0059 0.0155 0.0155
Toxoplasma gondii ATP-dependent RNA helicase DDX1, putative 0.0013 0.0006 0.0174
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0025 0.0025
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0194 0.0233
Leishmania major hypothetical protein, conserved 0.0723 0.2283 1
Toxoplasma gondii SPRY domain-containing protein 0.0013 0.0006 0.0174
Trypanosoma brucei protein I/6 0.0018 0.0023 0.005
Loa Loa (eye worm) ion channel NompC 0.0019 0.0025 0.0038
Onchocerca volvulus 0.0016 0.0015 0.0067
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0025 0.0027
Echinococcus granulosus calcium uptake protein 1 0.0018 0.0023 0.0023
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0025 0.0026
Leishmania major cathepsin L-like protease 0.0018 0.0023 0.0076
Leishmania major hypothetical protein, unknown function 0.0019 0.0025 0.0085
Echinococcus multilocularis calumenin 0.0018 0.0023 0.0023
Trypanosoma cruzi glyoxalase II 0.0016 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0038
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0194 0.0298
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0194 0.056
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0019 0.0025 0.0022
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0034 0.0037
Schistosoma mansoni hypothetical protein 0.0728 0.2297 0.2297
Mycobacterium ulcerans hypothetical protein 0.0016 0.0015 0.0114
Echinococcus granulosus stromal cell derived factor 2 0.0198 0.0598 0.0726
Leishmania major cathepsin L-like protease 0.0069 0.0187 0.0794
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0003 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0187 0.0537
Trypanosoma brucei caltractin, putative 0.0018 0.0023 0.005
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0018 0.0023 0.0023
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Trypanosoma brucei centrin, putative 0.0018 0.0023 0.005
Echinococcus multilocularis sodium channel protein 0.0019 0.0025 0.0026
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0016 0.0015 0.0027
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0023 0.2228
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0059 0.0157
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0146 0.0433 0.0665
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0025 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0216 0.1282
Trypanosoma brucei trypanothione reductase 0.0037 0.0083 0.0231
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0363 0.0439
Giardia lamblia Kinase, PLK 0.02 0.0607 1
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0023 0.005
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0266 0.7174
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0025 0.0026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0023 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0005
Trypanosoma cruzi centrin, putative 0.0018 0.0023 0.005
Trichomonas vaginalis beta lactamase domain, putative 0.0016 0.0015 0.0067
Leishmania major i/6 autoantigen-like protein 0.0018 0.0023 0.0074
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0101 0.0288 0.0441
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0025 0.0026
Toxoplasma gondii hypothetical protein 0.0019 0.0025 0.0753
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0018 0.0023 0.005
Trypanosoma brucei calmodulin, putative 0.0018 0.0023 0.005
Brugia malayi hypothetical protein 0.0133 0.0391 0.0388
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0016 0.0015 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0025 0.0128
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0025 0.0027
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0025 0.0026
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0019 0.0025 0.0025
Echinococcus granulosus muscleblind protein 0.0146 0.0433 0.0524
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0018 0.0023 0.0023
Mycobacterium tuberculosis Possible hydrolase 0.0016 0.0015 0.0114
Schistosoma mansoni ets-related 0.0251 0.077 0.077
Brugia malayi hypothetical protein 0.0048 0.0118 0.0115
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0091 0.0254
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0018 0.0023 0.0023
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0025 0.0026
Brugia malayi Ets-domain containing protein 0.0083 0.023 0.0227
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0007 0.0005
Schistosoma mansoni calmodulin 0.0018 0.0023 0.0023
Echinococcus granulosus shaker cognate 0.0019 0.0025 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0008 0.0024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0071 0.0082
Trichomonas vaginalis calmodulin, putative 0.0018 0.0023 0.0113
Onchocerca volvulus 0.0018 0.0023 0.0116
Leishmania major cathepsin L-like protease 0.0018 0.0023 0.0076
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0187 0.0537
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0006 0.0095
Loa Loa (eye worm) hypothetical protein 0.0133 0.0391 0.06
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0008 0.0024
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0004 0.0004
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0031 0.0063 0.7363
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0025 0.0025

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Selectivity index, ratio of CC50 for MDBK cells to EC50 for BVDV ChEMBL. 17084081
CC50 (ADMET) = 9.7 uM Cytotoxicity against Huh 5-2 cells ChEMBL. 17084081
CC50 (ADMET) = 25 uM Cytotoxicity against MDBK cells ChEMBL. 17084081
EC50 (functional) = 4.9 uM Antiviral activity against HCV in Huh 5-2 cells assessed as reduction of virus-induced cytopathic efect ChEMBL. 17084081
EC50 (functional) > 25 uM Antiviral activity against BVDV in MDBK cells assessed as reduction of virus-induced cytopathic efect ChEMBL. 17084081
Ratio CC50/EC50 (functional) = 2 Selectivity index, ratio of CC50 for Huh 5-2 cells to EC50 for HCV ChEMBL. 17084081

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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