Detailed information for compound 437242

Basic information

Technical information
  • TDR Targets ID: 437242
  • Name: 2-(2-ethyl-1H-indol-3-yl)acetic acid
  • MW: 203.237 | Formula: C12H13NO2
  • H donors: 2 H acceptors: 2 LogP: 2.34 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1[nH]c2c(c1CC(=O)O)cccc2
  • InChi: 1S/C12H13NO2/c1-2-10-9(7-12(14)15)8-5-3-4-6-11(8)13-10/h3-6,13H,2,7H2,1H3,(H,14,15)
  • InChiKey: UYWGYIXTYGHANH-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-(2-ethyl-1H-indol-3-yl)ethanoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Giardia lamblia Kinase, NEK 0.0171 0.0283 0.1175
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0142 0.1484
Echinococcus multilocularis tyrosine protein kinase Blk 0.0221 0.0422 0.0422
Schistosoma mansoni tyrosine kinase 0.0508 0.1219 0.1217
Echinococcus multilocularis dual specificity mitogen activated protein 0.022 0.0418 0.0418
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0174 0.0291 0.342
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0225 0.0432 0.0432
Loa Loa (eye worm) TK/EGFR protein kinase 0.0792 0.2006 0.2006
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0174 0.0292 0.2627
Brugia malayi Protein kinase domain containing protein 0.0196 0.0351 0.0351
Schistosoma mansoni vav2 0.0136 0.0186 0.0184
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0163 0.0261 0.0261
Loa Loa (eye worm) AGC/NDR protein kinase 0.0241 0.0477 0.0477
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0127 0.1132
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0477 0.1133 0.1133
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1105 0.1103
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0316 0.0684 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0482 0.048
Brugia malayi Protein kinase domain containing protein 0.0127 0.016 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0261 0.118
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0174 0.0291 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.017 0.028 0.0278
Trypanosoma cruzi casein kinase, putative 0.0142 0.0201 0.1806
Trichomonas vaginalis STE family protein kinase 0.022 0.0418 0.1895
Brugia malayi Protein kinase c protein 2 0.0208 0.0385 0.0385
Onchocerca volvulus 0.0127 0.016 0.0467
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.008 0.0029 0.0239
Echinococcus multilocularis dual specificity protein kinase clk2 0.019 0.0336 0.0336
Brugia malayi Fibronectin type III domain containing protein 0.0117 0.0131 0.0131
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0074 0.0014 0.0014
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0174 0.0291 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0014 0.0012
Giardia lamblia Kinase, NEK 0.0171 0.0283 0.1175
Loa Loa (eye worm) hypothetical protein 0.0129 0.0165 0.0165
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.019 0.0334 0.0334
Echinococcus multilocularis cyclin dependent kinase 19 0.0201 0.0367 0.0367
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0279 0.0279
Entamoeba histolytica casein kinase 1, putative 0.0142 0.0201 0.212
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0117 0.0134 0.0134
Echinococcus multilocularis cyclin dependent kinase 9 0.0109 0.011 0.011
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0124 0.0151 0.0151
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Loa Loa (eye worm) SRC-1 0.0266 0.0545 0.0545
Giardia lamblia Kinase, CMGC CK2 0.0133 0.0176 0.068
Trichomonas vaginalis STE family protein kinase 0.008 0.0029 0.012
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0101 0.0089 0.0089
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0651 0.1616 0.1616
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.3671 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0142 0.0201 0.0908
Echinococcus multilocularis mitogen activated protein kinase 14 0.0467 0.1105 0.1105
Schistosoma mansoni ephrin receptor 0.0129 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.012 0.0141 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0222 0.022
Echinococcus granulosus tyrosine protein kinase HCK 0.0154 0.0236 0.0236
Echinococcus multilocularis serine:threonine protein kinase 38 0.0241 0.0477 0.0477
Echinococcus granulosus casein kinase I delta 0.0142 0.0201 0.0201
Echinococcus granulosus roundabout 2 0.007 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0393 0.0899 0.0899
Echinococcus multilocularis aurora kinase A 0.0181 0.0311 0.0311
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0114 0.0125 0.0125
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0467 0.1105 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0266 0.0545 0.0545
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0149 0.0222 0.0222
Echinococcus granulosus protein tyrosine kinase 0.0604 0.1484 0.1484
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0351 0.1591
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0133 0.0177 0.0177
Loa Loa (eye worm) CMGC/CLK protein kinase 0.019 0.0336 0.0336
Giardia lamblia Kinase, PLK 0.0316 0.0684 0.3021
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0174 0.0291 0.342
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0116 0.013 0.1157
Schistosoma mansoni kinase 0.0109 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0117 0.0131 0.0131
Brugia malayi Doublecortin family protein 0.0187 0.0327 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0205 0.0203
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0121 0.0144 0.1285
Loa Loa (eye worm) TK protein kinase 0.0386 0.0879 0.0879
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0114 0.0124 0.0556
Entamoeba histolytica protein kinase, putative 0.0114 0.0125 0.1309
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0114 0.0125 0.1115
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.008 0.0029 0.0239
Echinococcus granulosus MAP kinase activated protein kinase 2 0.3671 1 1
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0252 0.0508 0.459
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0311 0.1408
Plasmodium falciparum serine/threonine protein kinase 0.0114 0.0125 0.3521
Echinococcus granulosus protein kinase c iota type 0.039 0.089 0.089
Giardia lamblia Kinase, CMGC CDK 0.0196 0.0351 0.1489
Giardia lamblia Kinase, CMGC CLK 0.019 0.0336 0.1416
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0292 0.0619 0.0619
Trypanosoma brucei protein kinase, putative 0.0124 0.0151 0.1346
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0142 0.0201 0.0201
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0029 0.012
Trypanosoma cruzi polo-like protein kinase, putative 0.0316 0.0684 0.618
Brugia malayi Protein kinase domain containing protein 0.0127 0.016 0.016
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0196 0.0351 0.0351
Echinococcus multilocularis cyclin dependent kinase 9 0.0117 0.0134 0.0134
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.019 0.0336 0.3024
Brugia malayi bone morphogenetic protein type 1 receptor 0.0137 0.0188 0.0188
Brugia malayi Protein kinase domain containing protein 0.1038 0.2688 0.2688
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0404 0.0929 0.3314
Echinococcus multilocularis 0.0311 0.0672 0.0672
Toxoplasma gondii aurora kinase 0.0181 0.0311 0.3665
Onchocerca volvulus Serine\/threonine kinase homolog 0.0316 0.0684 0.2405
Echinococcus granulosus dual specificity mitogen activated protein 0.022 0.0418 0.0418
Trypanosoma cruzi cdc2-related kinase 1 0.0196 0.0351 0.3167
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0112 0.0119 0.1384
Brugia malayi Protein kinase domain containing protein 0.1055 0.2737 0.2737
Entamoeba histolytica protein kinase, putative 0.0094 0.0069 0.0712
Trichomonas vaginalis CMGC family protein kinase 0.0861 0.2198 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0196 0.0351 0.0351
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0125 0.0123
Brugia malayi Protein kinase domain containing protein 0.0613 0.1509 0.1509
Echinococcus granulosus protein kinase c epsilon type 0.0303 0.065 0.065
Schistosoma mansoni protein kinase 0.0137 0.0188 0.0186
Echinococcus granulosus cyclin dependent kinase 9 0.0117 0.0134 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0127 0.0125
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0181 0.0309 0.0309
Plasmodium falciparum NIMA related kinase 1 0.0171 0.0283 0.8054
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.008 0.0029 0.0239
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0266 0.0545 0.0545
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.067 0.1668 0.1668
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0181 0.0311 0.329
Brugia malayi Protein kinase domain containing protein 0.0248 0.0496 0.0496
Echinococcus granulosus serine threonine protein kinase nrc 0.0193 0.0345 0.0345
Loa Loa (eye worm) protein kinase domain-containing protein 0.0254 0.0514 0.0514
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0181 0.0309 0.0309
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Brugia malayi Protein kinase domain containing protein 0.0114 0.0125 0.0125
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0181 0.0311 0.329
Trichomonas vaginalis AGC family protein kinase 0.0113 0.012 0.0538
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0404 0.0929 0.0929
Toxoplasma gondii CMGC kinase, CK2 family 0.0133 0.0176 0.206
Loa Loa (eye worm) casein kinase 0.0194 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0153 0.0232 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0311 0.1408
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.007 0.0002 0.0002
Echinococcus granulosus casein kinase I alpha 0.0142 0.0201 0.0201
Giardia lamblia Kinase, AGC AKT 0.0151 0.0227 0.0913
Entamoeba histolytica casein kinase, putative 0.0142 0.0201 0.212
Echinococcus multilocularis basement membrane specific heparan sulfate 0.01 0.0085 0.0085
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Echinococcus granulosus tyrosine kinase 0.0221 0.0422 0.0422
Trypanosoma cruzi cdc2-related kinase 1 0.0196 0.0351 0.3167
Brugia malayi Kinase associated domain 1 family protein 0.011 0.0112 0.0112
Echinococcus multilocularis serine:threonine protein kinase N2 0.038 0.0864 0.0864
Trypanosoma brucei polo-like protein kinase 0.0316 0.0684 0.618
Brugia malayi Temporarily assigned gene name protein 59 0.0139 0.0193 0.0193
Brugia malayi Protein kinase domain containing protein 0.067 0.1668 0.1668
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0279 0.0279
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0467 0.1105 1
Schistosoma mansoni tyrosine kinase 0.0266 0.0545 0.0543
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0283 0.1281
Echinococcus multilocularis transfer RNA-Thr 0.0238 0.0469 0.0469
Schistosoma mansoni tyrosine kinase 0.0529 0.1278 0.1276
Echinococcus multilocularis serine:threonine protein kinase 3 0.0301 0.0644 0.0644
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0124 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0127 0.016 0.016
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.021
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.008 0.0029 0.0754
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0199 0.0359 0.0359
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0309 0.0666 0.0666
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0389 0.0887 0.0887
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0193 0.0345 0.3104
Echinococcus granulosus CDC7 cell division cycle 7 0.0861 0.2198 0.2198
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0187 0.0327 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0432 0.043
Brugia malayi Protein kinase domain containing protein 0.0201 0.0367 0.0367
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0196 0.0351 0.0351
Brugia malayi hypothetical protein 0.012 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0117 0.0131 0.0131
Echinococcus granulosus TGF-beta receptor type-1 0.0138 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0154 0.0236 0.0236
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0287 0.0606 0.0606
Plasmodium falciparum calcium-dependent protein kinase 1 0.0174 0.0291 0.826
Echinococcus multilocularis protein KINase family member (kin 25) 0.0129 0.0165 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.3671 1 1
Echinococcus multilocularis expressed conserved protein 0.017 0.0279 0.0279
Entamoeba histolytica protein kinase, putative 0.0117 0.0134 0.1401
Loa Loa (eye worm) AGC/PKA protein kinase 0.0147 0.0214 0.0214
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0185 0.0321 0.0321
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0216 0.0407 0.0407
Trichomonas vaginalis AGC family protein kinase 0.0285 0.0599 0.2717
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0619 0.0618
Echinococcus multilocularis beta adrenergic receptor kinase 0.0074 0.0014 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0214 0.0967
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus multilocularis 0.019 0.0334 0.0334
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.008 0.0029 0.0239
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0181 0.0311 0.8852
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.012 0.0141 0.0141
Schistosoma mansoni protein kinase 0.019 0.0334 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0252 0.0508 0.459
Loa Loa (eye worm) hypothetical protein 0.0123 0.0148 0.0148
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0129 0.0165 0.0165
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0124 0.0151 0.0151
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0127 0.1132
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0467 0.1105 1
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0116 0.013 0.1157
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0279 0.0277
Echinococcus granulosus fibroblast growth factor receptor 4 0.0273 0.0566 0.0566
Brugia malayi Protein kinase domain containing protein 0.0241 0.0477 0.0477
Echinococcus granulosus c-Jun N-terminal kinases 0.0309 0.0666 0.0666
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0221 0.0422 0.0422
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0477 0.0475
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0085 0.0044 0.0044
Plasmodium falciparum NIMA related kinase 4 0.008 0.0029 0.0754
Brugia malayi Protein kinase domain containing protein 0.0092 0.0062 0.0062
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0147 0.0214 0.1925
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus multilocularis NCK adaptor protein 0.0115 0.0127 0.0127
Brugia malayi Protein kinase domain containing protein 0.0113 0.012 0.012
Trypanosoma cruzi casein kinase, putative 0.0142 0.0201 0.1806
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0351 0.1591
Schistosoma mansoni ste20-related kinase 0.0246 0.0489 0.0488
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0556 0.1353 0.1353
Loa Loa (eye worm) hypothetical protein 0.0238 0.0469 0.0469
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0273 0.0566 0.0566
Echinococcus multilocularis CDC7 cell division cycle 7 0.0861 0.2198 0.2198
Brugia malayi Protein kinase domain containing protein 0.0241 0.0476 0.0476
Schistosoma mansoni serine/threonine protein kinase 0.0861 0.2198 0.2196
Schistosoma mansoni tyrosine kinase 0.0604 0.1484 0.1483
Brugia malayi Tyrosine-protein kinase abl-1 0.0138 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0128 0.0163 0.0163
Plasmodium vivax serine/threonine kinase-1, putative 0.019 0.0336 0.9549
Loa Loa (eye worm) hypothetical protein 0.01 0.0085 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0214 0.0213
Brugia malayi Serine/threonine-protein kinase Nek7 0.0283 0.0594 0.0594
Entamoeba histolytica protein kinase, putative 0.0177 0.0298 0.315
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Brugia malayi p70 ribosomal S6 kinase beta 0.0374 0.0846 0.0846
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.022 0.0418 0.3773
Schistosoma mansoni Neurotrimin precursor (hNT) 0.01 0.0085 0.0083
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0252 0.0508 0.0508
Brugia malayi hypothetical protein 0.0467 0.1105 0.1105
Echinococcus multilocularis serine:threonine protein kinase 0.0148 0.0218 0.0218
Entamoeba histolytica serine/threonine protein kinase, putative 0.0316 0.0684 0.7253
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.012 0.0141 0.0141
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0104 0.0098 0.0434
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0117 0.0134 0.0134
Giardia lamblia Kinase, CDC7 0.0861 0.2198 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0127 0.0127
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0214 0.0402 0.0402
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Giardia lamblia Kinase, CMGC SRPK 0.0114 0.0125 0.0446
Entamoeba histolytica protein kinase, putative 0.0241 0.0477 0.5049
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Brugia malayi Protein kinase domain 0.0117 0.0134 0.0134
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0285 0.0599 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0359 0.0357
Leishmania major protein kinase, putative 0.008 0.0029 0.0239
Schistosoma mansoni protein kinase 0.0117 0.0134 0.0132
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0171 0.0283 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus multilocularis protein kinase c epsilon type 0.0303 0.065 0.065
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0137 0.0188 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0002 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0127 0.0569
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Brugia malayi Protein kinase domain containing protein 0.0258 0.0525 0.0525
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0467 0.1105 0.1105
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0467 0.1105 1
Echinococcus multilocularis N chimaerin 0.0127 0.0159 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Loa Loa (eye worm) hypothetical protein 0.01 0.0085 0.0085
Echinococcus granulosus mitogen activated protein kinase 14 0.0467 0.1105 0.1105
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0147 0.0214 0.1925
Chlamydia trachomatis serine/threonine protein kinase 0.0283 0.0594 0.5
Trypanosoma cruzi casein kinase II, putative 0.0133 0.0176 0.1575
Echinococcus granulosus raf serine:threonine protein kinase 0.012 0.0139 0.0139
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0129 0.0165 0.0165
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0266 0.0545 0.0545
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0127 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0619 0.0618
Plasmodium vivax serine/threonine protein kinase, putative 0.0114 0.0125 0.3521
Trichomonas vaginalis STE family protein kinase 0.0116 0.013 0.0581
Loa Loa (eye worm) hypothetical protein 0.0148 0.0218 0.0218
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0301 0.0644 0.0644
Echinococcus multilocularis mitogen activated protein kinase 11 0.0467 0.1105 0.1105
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0114 0.0125 0.1115
Trichomonas vaginalis CMGC family protein kinase 0.0861 0.2198 1
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.019 0.0336 0.3024
Brugia malayi RhoGAP domain containing protein 0.0127 0.0159 0.0159
Entamoeba histolytica protein kinase, putative 0.0374 0.0846 0.8976
Trypanosoma cruzi Protein kinase B 0.0203 0.0371 0.3346
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Schistosoma mansoni tyrosine kinase 0.0171 0.0283 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0311 0.1408
Entamoeba histolytica hypothetical protein 0.0409 0.0942 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0241 0.0476 0.0476
Onchocerca volvulus 0.0154 0.0234 0.0741
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.016 0.0253 0.2276
Loa Loa (eye worm) hypothetical protein 0.0117 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.012 0.0141 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0116 0.013 0.1157
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.022 0.0418 0.0418
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0243 0.0482 0.0482
Entamoeba histolytica PH domain containing protein kinase, putative 0.0203 0.0371 0.3927
Schistosoma mansoni tyrosine kinase 0.0266 0.0545 0.0543
Plasmodium falciparum calcium-dependent protein kinase 2 0.0174 0.0291 0.826
Entamoeba histolytica protein kinase domain containing protein 0.0181 0.0311 0.329
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.022 0.0418 0.3773
Entamoeba histolytica protein kinase domain containing protein 0.0109 0.011 0.1149
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0127 0.0159 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0279 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0419 0.0972 0.0972
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Brugia malayi Protein kinase domain containing protein 0.0384 0.0872 0.0872
Onchocerca volvulus 0.0861 0.2198 0.8006
Echinococcus multilocularis death associated protein kinase 1 0.0937 0.2409 0.2409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0705 0.1764 0.1764
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0133 0.0177 0.0177
Echinococcus granulosus cyclin dependent kinase 0.0196 0.0351 0.0351
Loa Loa (eye worm) TK/INSR protein kinase 0.0529 0.1278 0.1278
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0287 0.0606 0.0606
Echinococcus granulosus cyclin dependent kinase 1 0.0196 0.0351 0.0351
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0666 0.0664
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0453 0.1065 0.1065
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0114 0.0124 0.0556
Echinococcus multilocularis RNA directed DNA polymerase 0.0085 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0077 0.002 0.002
Schistosoma mansoni hypothetical protein 0.012 0.0141 0.0139
Plasmodium vivax calcium-dependent protein kinase, putative 0.0174 0.0291 0.826
Echinococcus granulosus tyrosine protein kinase Blk 0.0221 0.0422 0.0422
Schistosoma mansoni pyruvate dehydrogenase 0.0121 0.0145 0.0143
Echinococcus granulosus casein kinase i 0.0142 0.0201 0.0201
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.067 0.1668 0.1668
Echinococcus multilocularis rho associated protein kinase 0.0375 0.0848 0.0848
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0193 0.0345 0.9804
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0029 0.012
Entamoeba histolytica protein kinase domain containing protein 0.0163 0.0261 0.2756
Leishmania major protein kinase, putative 0.012 0.0142 0.1265
Brugia malayi kinase, mitochondrial precursor 0.0129 0.0165 0.0165
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Plasmodium falciparum cGMP-dependent protein kinase 0.017 0.0279 0.7921
Trypanosoma cruzi polo-like protein kinase, putative 0.0316 0.0684 0.618
Echinococcus multilocularis serine threonine protein kinase 0.0329 0.0721 0.0721
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0142 0.0201 0.1806
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0116 0.013 0.1358
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0113 0.012 0.012
Echinococcus granulosus N chimaerin 0.0127 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0358 0.0802 0.0802
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0127 0.1132
Echinococcus multilocularis neuroglian 0.007 0.0002 0.0002
Echinococcus granulosus Immunoglobulin 0.01 0.0085 0.0085
Trypanosoma brucei rac serine-threonine kinase, putative 0.0384 0.0872 0.789
Entamoeba histolytica protein kinase, putative 0.0384 0.0872 0.926
Echinococcus granulosus tyrosine protein kinase ABL1 0.035 0.0779 0.0779
Schistosoma mansoni ephrin receptor 0.0077 0.0021 0.0019
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0546 0.1324 0.1324
Schistosoma mansoni protein kinase 0.0181 0.0311 0.0309
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0117 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Plasmodium vivax unspecified product 0.0133 0.0176 0.4975
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0084 0.004 0.004
Echinococcus granulosus roundabout 2 0.017 0.0279 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0254 0.1148
Brugia malayi Cam kinase protein 1 0.0174 0.0291 0.0291
Echinococcus multilocularis growth factor receptor bound protein 2 0.0111 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0143 0.0205 0.0205
Trypanosoma brucei NIMA-related protein kinase 0.008 0.0029 0.0239
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0174 0.0291 0.0291
Brugia malayi protein-tyrosine kinase 0.0221 0.0422 0.0422
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0181 0.0311 0.0311
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0121 0.0144 0.1285
Loa Loa (eye worm) TK/ALK protein kinase 0.0612 0.1508 0.1508
Trichomonas vaginalis STE family protein kinase 0.0117 0.0134 0.06
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.004 0.0038
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.013 0.0168 0.4735
Loa Loa (eye worm) hypothetical protein 0.012 0.0141 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.019 0.0336 0.3024
Echinococcus granulosus protein kinase C gamma type 0.0329 0.0721 0.0721
Brugia malayi Stress-activated protein kinase jnk-1 0.0309 0.0666 0.0666
Echinococcus granulosus tyrosine kinase 0.0127 0.016 0.016
Echinococcus multilocularis titin 0.0107 0.0106 0.0106
Trichomonas vaginalis STE family protein kinase 0.022 0.0418 0.1895
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Echinococcus multilocularis casein kinase I alpha 0.0142 0.0201 0.0201
Brugia malayi Variant SH3 domain containing protein 0.0111 0.0116 0.0116
Onchocerca volvulus 0.0107 0.0104 0.0261
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0141 0.0139
Echinococcus multilocularis hypothetical protein 0.011 0.0112 0.0112
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0101 0.0089 0.0089
Echinococcus multilocularis TGF beta receptor type 1 0.0138 0.019 0.019
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Echinococcus granulosus tyrosine protein kinase Srms 0.0565 0.1377 0.1377
Onchocerca volvulus Serine\/threonine kinase homolog 0.0201 0.0367 0.1233
Schistosoma mansoni protein kinase 0.0287 0.0606 0.0604
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0149 0.0222 0.0222
Schistosoma mansoni protein kinase 0.0117 0.0134 0.0132
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.0283 0.0594 0.0594
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0225 0.0432 0.0432
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Echinococcus granulosus calcium activated potassium channel 0.017 0.028 0.028
Giardia lamblia Kinase, CMGC CDK 0.0196 0.0351 0.1489
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0594 0.0592
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0111 0.0116 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.019 0.0188
Onchocerca volvulus 0.0861 0.2198 0.8006
Echinococcus multilocularis Immunoglobulin 0.01 0.0085 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0477 0.0475
Echinococcus granulosus nervana 2 0.0133 0.0177 0.0177
Loa Loa (eye worm) AUR protein kinase 0.0181 0.0311 0.0311
Brugia malayi protein kinase C3,putative 0.0209 0.0389 0.0389
Leishmania major casein kinase II, putative 0.0133 0.0176 0.1575
Entamoeba histolytica protein kinase, putative 0.0174 0.0291 0.307
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0086 0.0047 0.0047
Plasmodium vivax casein kinase 1, putative 0.0142 0.0201 0.5705
Brugia malayi Casein kinase II, alpha chain 0.0133 0.0176 0.0176
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0148 0.0218 0.0218
Mycobacterium ulcerans hypothetical protein 0.0109 0.0111 0.5
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0111 0.0116 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Entamoeba histolytica protein kinase, putative 0.0181 0.0311 0.329
Brugia malayi Variant SH3 domain containing protein 0.0079 0.0028 0.0028
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0127 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0029 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.012 0.0142 0.1265
Echinococcus multilocularis casein kinase ii subunit alpha 0.0133 0.0176 0.0176
Echinococcus multilocularis dual specificity 0.0174 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.013 0.0168 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0174 0.0291 0.0291
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0174 0.0291 0.0291
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0174 0.0292 0.2627
Brugia malayi Protein kinase domain containing protein 0.0127 0.016 0.016
Echinococcus granulosus roundabout 2 0.007 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Plasmodium falciparum protein serine/threonine kinase-1 0.019 0.0336 0.9549
Toxoplasma gondii AGC kinase 0.0374 0.0846 1
Trichomonas vaginalis AGC family protein kinase 0.0295 0.0625 0.2839
Plasmodium vivax protein kinase Crk2 0.0196 0.0351 1
Trypanosoma brucei developmentally regulated phosphoprotein 0.0129 0.0165 0.1474
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0225 0.0432 0.0432
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.012 0.0142 0.1265
Loa Loa (eye worm) TK/FAK protein kinase 0.061 0.1502 0.1502
Brugia malayi STE20-like kinase MST 0.0301 0.0644 0.0644
Echinococcus granulosus defective proboscis extension response 0.01 0.0085 0.0085
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0117 0.0134 0.0134
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0147 0.0214 0.2516
Schistosoma mansoni protein kinase 0.031 0.0668 0.0666
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Giardia lamblia Kinase, CAMK CAMKL 0.013 0.0168 0.0641
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0127 0.0159 0.0157
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0266 0.0545 0.0545
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.0131 0.0131
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0151 0.0227 0.0227
Schistosoma mansoni protein kinase 0.0142 0.0201 0.02
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0181 0.0311 0.0311
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0149 0.0221 0.0221
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0181 0.0309 0.0309
Entamoeba histolytica protein kinase, putative 0.0101 0.0089 0.0919
Echinococcus granulosus insulin receptor 0.0529 0.1278 0.1278
Trypanosoma brucei casein kinase I, isoform 2 0.0142 0.0201 0.1806
Brugia malayi Protein kinase domain containing protein 0.0126 0.0158 0.0158
Echinococcus multilocularis tyrosine protein kinase 0.0318 0.0689 0.0689
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus granulosus activated cdc42 kinase 1 0.0238 0.0469 0.0469
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0101 0.0089 0.0089
Entamoeba histolytica serine/threonine protein kinase, putative 0.0121 0.0144 0.1509
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0266 0.0545 0.0545
Echinococcus multilocularis tyrosine protein kinase HCK 0.0154 0.0236 0.0236
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Trypanosoma brucei SNF1-related protein kinases, putative 0.0121 0.0144 0.1285
Echinococcus multilocularis cyclin dependent kinase 5 0.0196 0.0351 0.0351
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0292 0.029
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0241 0.0476 0.0476
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0113 0.012 0.012
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Entamoeba histolytica protein kinase, putative 0.0181 0.0311 0.329
Brugia malayi Hr1 repeat family protein 0.038 0.0864 0.0864
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0084 0.004 0.004
Entamoeba histolytica protein kinase 2, putative 0.0193 0.0345 0.3644
Loa Loa (eye worm) hypothetical protein 0.0393 0.0899 0.0899
Leishmania major protein kinase A catalytic subunit isoform 2 0.0147 0.0214 0.1925
Schistosoma mansoni protein kinase 0.0651 0.1616 0.1614
Schistosoma mansoni serine/threonine protein kinase 0.0389 0.0887 0.0885
Echinococcus multilocularis mitogen activated protein kinase 11 0.0467 0.1105 0.1105
Brugia malayi Fes/CIP4 homology domain containing protein 0.0126 0.0157 0.0157
Schistosoma mansoni vam6/vps39 related 0.012 0.0141 0.0139
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0205 0.0203
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0121 0.0144 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0351 0.035
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0241 0.0477 0.0477
Echinococcus multilocularis nervana 2 0.0133 0.0177 0.0177
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0111 0.0116 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Onchocerca volvulus 0.0127 0.016 0.0467
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0193 0.0345 0.0345
Echinococcus granulosus serine:threonine kinase SAD 1 0.0121 0.0144 0.0144
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0467 0.1105 0.1105
Loa Loa (eye worm) hypothetical protein 0.0298 0.0636 0.0636
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.3671 1 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0117 0.0134 0.0134
Toxoplasma gondii NEK kinase 0.008 0.0029 0.0312
Brugia malayi phosphoinositide-dependent protein kinase I 0.0113 0.012 0.012
Giardia lamblia Kinase, STE STE20 0.0117 0.0134 0.0486
Loa Loa (eye worm) CAMK protein kinase 0.0107 0.0106 0.0106
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Giardia lamblia Kinase, NEK 0.0171 0.0283 0.1175
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1104 0.2873 0.2873
Entamoeba histolytica cell division protein kinase 2, putative 0.0204 0.0375 0.3968
Echinococcus granulosus NDR protein kinase 0.0241 0.0477 0.0477
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Loa Loa (eye worm) IKK protein kinase 0.1055 0.2737 0.2737
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0458 0.1079 0.1079
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0477 0.1133 0.1133
Echinococcus multilocularis cyclin dependent kinase 0.0196 0.0351 0.0351
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0243 0.0482 0.0482
Toxoplasma gondii casein kinase I 0.0142 0.0201 0.2362
Brugia malayi Protein kinase domain containing protein 0.0238 0.0469 0.0469
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus granulosus dual specificity protein kinase clk2 0.019 0.0336 0.0336
Echinococcus granulosus expressed protein 0.0114 0.0125 0.0125
Entamoeba histolytica PH domain containing protein kinase, putative 0.0203 0.0371 0.3927
Trypanosoma brucei cdc2-related kinase 1 0.0196 0.0351 0.3167
Schistosoma mansoni tyrosine kinase 0.0508 0.1219 0.1217
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0365
Brugia malayi cyclin-dependent kinase 7 homolog 0.0152 0.0229 0.0229
Entamoeba histolytica PH domain containing protein kinase, putative 0.0156 0.0241 0.2543
Schistosoma mansoni protein kinase 0.012 0.0142 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.004 0.0038
Echinococcus granulosus mitogen activated protein kinase 11 0.0467 0.1105 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0254 0.1148
Echinococcus multilocularis tyrosine protein kinase ABL1 0.035 0.0779 0.0779
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0316 0.0684 0.0684
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0126 0.0158 0.0158
Entamoeba histolytica protein kinase, putative 0.0113 0.012 0.1257
Echinococcus multilocularis calcium dependent protein kinase 0.0114 0.0123 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Plasmodium falciparum protein kinase 5 0.0196 0.0351 1
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0171 0.0283 0.8054
Plasmodium falciparum NIMA related kinase 2 0.008 0.0029 0.0754
Echinococcus multilocularis expressed protein 0.0114 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.011 0.0112 0.011
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0104 0.0098 0.0434
Loa Loa (eye worm) hypothetical protein 0.0135 0.0184 0.0184
Echinococcus granulosus beta-adrenergic receptor kinase 0.0074 0.0014 0.0014
Echinococcus granulosus hypothetical protein 0.013 0.0168 0.0168
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0002 0.0002
Onchocerca volvulus 0.0127 0.016 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0144 0.0142
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0174 0.0292 0.3435
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0174 0.0291 0.826
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0129 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0154 0.0234 0.0234
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0203 0.0371 0.3346
Echinococcus multilocularis activated cdc42 kinase 1 0.0238 0.0469 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0214 0.0213
Echinococcus granulosus serine:threonine protein kinase N2 0.038 0.0864 0.0864
Trichomonas vaginalis STE family protein kinase 0.0094 0.0069 0.0305
Brugia malayi Protein kinase domain containing protein 0.0252 0.0508 0.0508
Onchocerca volvulus 0.0109 0.011 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.1301 0.1299
Echinococcus granulosus RNA directed DNA polymerase 0.0085 0.0044 0.0044
Echinococcus multilocularis serine:threonine protein kinase N2 0.0241 0.0477 0.0477
Schistosoma mansoni protein kinase 0.0651 0.1616 0.1614
Onchocerca volvulus 0.0223 0.0426 0.1453
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0163 0.0261 0.0261
Loa Loa (eye worm) AUR protein kinase 0.0181 0.0311 0.0311
Echinococcus granulosus casein kinase I alpha 0.0142 0.0201 0.0201
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0147 0.0214 0.6078
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.007 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0127 0.0159 0.0159
Echinococcus multilocularis tyrosine kinase 0.0127 0.016 0.016
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.017 0.0279 0.328
Schistosoma mansoni serine/threonine protein kinase 0.017 0.028 0.0278
Brugia malayi hypothetical protein 0.0127 0.016 0.016
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.022 0.0418 0.0418
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.011 0.0108
Schistosoma mansoni protein kinase 0.0651 0.1616 0.1614
Echinococcus granulosus NCK adaptor protein 0.0111 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0113 0.0121 0.0119
Echinococcus granulosus cyclin dependent kinase 5 0.0196 0.0351 0.0351
Echinococcus multilocularis casein kinase I delta 0.0142 0.0201 0.0201
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0106 0.0106
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0331 0.0728 0.0728
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0141 0.126
Brugia malayi SRC-1 0.0266 0.0545 0.0545
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0241 0.0477 0.0477
Schistosoma mansoni protein kinase 0.0232 0.0453 0.0451
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Schistosoma mansoni serine/threonine protein kinase 0.038 0.0864 0.0862
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0221 0.0995
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0114 0.0125 0.1115
Brugia malayi Protein kinase domain containing protein 0.0861 0.2198 0.2198
Echinococcus multilocularis raf serine:threonine protein kinase 0.012 0.0139 0.0139
Echinococcus granulosus serine:threonine protein kinase 0.0148 0.0218 0.0218
Brugia malayi Furin-like cysteine rich region family protein 0.0792 0.2006 0.2006
Giardia lamblia Kinase, CAMK CAMKL 0.013 0.0168 0.0641
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus multilocularis PAK box P21 Rho binding 0.0094 0.0069 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.0218 0.0982
Echinococcus granulosus rho-associated protein kinase 1 0.0375 0.0848 0.0848
Brugia malayi SH2 domain containing protein 0.0127 0.016 0.016
Loa Loa (eye worm) TK protein kinase 0.0221 0.0422 0.0422
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0185 0.0321 0.0321
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0147 0.0214 0.6078
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0193 0.0345 0.9804
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0147 0.0214 0.1925
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0123 0.0148 0.0148
Schistosoma mansoni atypical protein kinase C 0.0396 0.0908 0.0906
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0148 0.022 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0221 0.0995
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.0341
Brugia malayi MAP kinase sur-1 0.0115 0.0127 0.0127
Echinococcus multilocularis cyclin dependent kinase 1 0.0196 0.0351 0.0351
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0257 0.0522 0.0522
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0127 0.148
Giardia lamblia Kinase, AGC PKA 0.0147 0.0214 0.0857
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0419 0.0972 0.0972
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0174 0.0291 0.0291
Echinococcus multilocularis twitchin 0.0091 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.1371 0.3615 0.3615
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0121 0.0144 0.1285
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0127 0.0159 0.0159
Plasmodium falciparum glycogen synthase kinase 3 0.0163 0.0261 0.7415
Schistosoma mansoni protein kinase 0.0094 0.0069 0.0067
Loa Loa (eye worm) gastrulation defective protein 1 0.0141 0.0199 0.0199
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0117 0.0134 0.0134
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0163 0.0261 0.2348
Brugia malayi Protein kinase domain containing protein 0.0285 0.0599 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0514 0.0512
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0142 0.0201 0.0201
Brugia malayi Variant SH3 domain containing protein 0.0111 0.0116 0.0116
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0127 0.1132
Echinococcus granulosus TGF beta receptor type 1 0.0138 0.019 0.019
Trichomonas vaginalis AGC family protein kinase 0.0285 0.0599 0.2717
Brugia malayi Protein kinase domain containing protein 0.0127 0.016 0.016
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.012 0.0142 0.1265
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0261 0.118
Loa Loa (eye worm) AUR protein kinase 0.0181 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0258 0.0523 0.0523
Trichomonas vaginalis CAMK family protein kinase 0.0258 0.0525 0.238
Echinococcus granulosus ephrin type A receptor 4 A 0.0129 0.0165 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0141 0.126
Echinococcus granulosus casein kinase I delta 0.0142 0.0201 0.0201
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0174 0.0291 0.826
Echinococcus multilocularis 0.013 0.0168 0.0168
Trypanosoma brucei Casein kinase II 0.0133 0.0176 0.1575
Brugia malayi ephrin receptor 1 precursor 0.0092 0.0064 0.0064
Echinococcus granulosus serine/threonine protein kinase 0.0203 0.0371 0.0371
Trichomonas vaginalis STE family protein kinase 0.0117 0.0134 0.06
Plasmodium falciparum calcium-dependent protein kinase 3 0.0174 0.0291 0.826
Loa Loa (eye worm) AGC/AKT protein kinase 0.0384 0.0872 0.0872
Schistosoma mansoni growth factor receptor-bound protein 0.0115 0.0127 0.0125
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0651 0.1616 0.1616
Loa Loa (eye worm) hypothetical protein 0.0298 0.0636 0.0636
Giardia lamblia Kinase, CMGC GSK 0.0163 0.0261 0.1073
Brugia malayi hypothetical protein 0.0117 0.0131 0.0131
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0174 0.0291 0.0291
Trichomonas vaginalis AGC family protein kinase 0.0249 0.05 0.2269
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0201 0.0367 0.0367
Brugia malayi C1-like domain containing protein 0.0274 0.0567 0.0567
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0274 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0254 0.0514 0.0514
Schistosoma mansoni kinase 0.0335 0.0739 0.0737
Echinococcus granulosus tyrosine protein kinase Lyn 0.0326 0.0713 0.0713
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0174 0.0292 0.2627
Echinococcus granulosus protein kinase shaggy 0.0163 0.0261 0.0261
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0174 0.0291 0.2615
Toxoplasma gondii histone kinase SNF1, putative 0.0121 0.0144 0.1681
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0568 0.1385 0.1385
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0171 0.0283 0.3334
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0351 0.035
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0185 0.0321 0.0321
Onchocerca volvulus 0.0375 0.0848 0.3011
Trichomonas vaginalis CK1 family protein kinase 0.0142 0.0201 0.0908
Echinococcus granulosus titin 0.0107 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0129 0.0165 0.0165
Brugia malayi Protein kinase domain containing protein 0.0419 0.0972 0.0972
Echinococcus multilocularis myosin iiia 0.0116 0.013 0.013
Entamoeba histolytica p21-activated kinase 0.0127 0.0161 0.1685
Echinococcus granulosus twitchin 0.019 0.0336 0.0336
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0147 0.0214 0.0214
Plasmodium falciparum serine/threonine protein kinase KIN 0.0121 0.0144 0.4059
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.007 0.0002 0.0002
Echinococcus granulosus calcium dependent protein kinase 0.0114 0.0123 0.0123
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0273 0.0566 0.0566
Plasmodium falciparum casein kinase 2, alpha subunit 0.0133 0.0176 0.4975
Entamoeba histolytica protein kinase domain containing protein 0.0163 0.0261 0.2756
Schistosoma mansoni protein kinase 0.0138 0.019 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0176 0.0791
Echinococcus granulosus neuroglian 0.007 0.0002 0.0002
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0142 0.0201 0.0201
Entamoeba histolytica serine/threonine protein kinase, putative 0.008 0.0029 0.028
Echinococcus multilocularis protein kinase shaggy 0.0163 0.0261 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0684 0.0682
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0311 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0144 0.0142
Schistosoma mansoni serine/threonine-protein kinase 0.0203 0.0371 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0144 0.0142
Echinococcus multilocularis tyrosine protein kinase Abl 0.0256 0.0519 0.0519
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.013 0.017 0.017
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0084 0.004 0.0173
Loa Loa (eye worm) hypothetical protein 0.0174 0.0291 0.0291
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0116 0.013 0.1358
Onchocerca volvulus 0.0213 0.04 0.1354
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0196 0.0351 0.3167
Echinococcus granulosus dual specificity 0.0174 0.0292 0.0292
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0086 0.0047 0.0047
Loa Loa (eye worm) TK/EPH protein kinase 0.0148 0.0217 0.0217
Schistosoma mansoni vesicular amine transporter 0.01 0.0085 0.0083
Echinococcus multilocularis dual specificity 0.0174 0.0292 0.0292
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0109 0.011 0.011
Echinococcus multilocularis neuroglian 0.013 0.0168 0.0168
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0279 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Entamoeba histolytica protein kinase, putative 0.0104 0.0096 0.0996
Schistosoma mansoni adapter molecule crk 0.0111 0.0116 0.0114
Giardia lamblia Aurora kinase 0.0181 0.0311 0.1304
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0138 0.019 0.019
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0084 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0336 0.0334
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0163 0.0261 0.307
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0351 0.1591
Onchocerca volvulus 0.0127 0.016 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0139 0.0138
Trichomonas vaginalis STE family protein kinase 0.0117 0.0134 0.06
Toxoplasma gondii AGC kinase 0.0147 0.0214 0.2516
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0367 0.0365
Schistosoma mansoni tyrosine kinase 0.0586 0.1434 0.1433
Echinococcus multilocularis roundabout 2 0.017 0.0279 0.0279
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0201 0.0367 0.0367
Echinococcus multilocularis casein kinase I alpha 0.0142 0.0201 0.0201
Trichomonas vaginalis STE family protein kinase 0.0117 0.0134 0.06
Echinococcus multilocularis dual specificity 0.0174 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0154 0.0234 0.0234
Echinococcus multilocularis Immunoglobulin 0.01 0.0085 0.0085
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0112 0.0119 0.3342
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0127 0.0569
Trichomonas vaginalis CMGC family protein kinase 0.0861 0.2198 1
Echinococcus granulosus tyrosine protein kinase 0.0318 0.0689 0.0689
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0336 0.1519
Brugia malayi cell division control protein 2 homolog 0.0149 0.0222 0.0222
Echinococcus granulosus casein kinase I gamma 0.0254 0.0514 0.0514
Brugia malayi Protein kinase domain containing protein 0.067 0.1668 0.1668
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0126 0.0158 0.0158
Entamoeba histolytica PH domain containing protein kinase, putative 0.0156 0.0241 0.2543
Trypanosoma brucei protein kinase, putative 0.012 0.0142 0.1265
Echinococcus multilocularis activin receptor type 0.0514 0.1236 0.1236
Echinococcus multilocularis insulin receptor 0.0529 0.1278 0.1278
Brugia malayi Protein kinase domain containing protein 0.0404 0.0929 0.0929
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.019 0.0336 0.3024
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0127 0.0127
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0292 0.0619 0.0619
Echinococcus granulosus contactin 0.007 0.0002 0.0002
Echinococcus granulosus Vam6:Vps39 protein 0.012 0.0141 0.0141
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.019 0.0336 0.3024
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0127 0.0127
Echinococcus granulosus cGMP dependent protein kinase 0.017 0.0279 0.0279
Leishmania major protein kinase, putative 0.019 0.0336 0.3024
Schistosoma mansoni protein kinase 0.0287 0.0606 0.0604
Loa Loa (eye worm) hypothetical protein 0.067 0.1668 0.1668
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0705 0.1764 0.1764
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0127 0.0569
Entamoeba histolytica protein kinase, putative 0.0384 0.0872 0.926
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0144 0.0142
Brugia malayi Protein kinase domain containing protein 0.019 0.0336 0.0336
Giardia lamblia Kinase, CK1 Casein kinase 0.0142 0.0201 0.0797
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0539 0.1305 0.1305
Echinococcus multilocularis Glutaredoxin protein 5 0.0133 0.0177 0.0177
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0174 0.0291 0.0291
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0174 0.0291 0.342
Giardia lamblia Kinase, STE STE20 0.022 0.0418 0.1797
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0147 0.0214 0.1925
Brugia malayi serine/threonine-protein kinase PAK 7 0.0275 0.057 0.057
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0174 0.0292 0.0292
Entamoeba histolytica hypothetical protein 0.0252 0.0508 0.5387
Schistosoma mansoni tyrosine kinase 0.0792 0.2006 0.2005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.012 0.0118
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0649 0.0649
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Echinococcus granulosus cyclin dependent kinase 7 0.0143 0.0205 0.0205
Loa Loa (eye worm) TK/ABL protein kinase 0.035 0.0779 0.0779
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0084 0.004 0.0345
Brugia malayi intracellular kinase 0.0163 0.0261 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0106 0.0104
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0331 0.0728 0.0728
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0174 0.0291 0.826
Brugia malayi protein kinase C II. 0.0303 0.065 0.065
Schistosoma mansoni tyrosine kinase 0.0568 0.1385 0.1384
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0266 0.0545 0.0545
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Trichomonas vaginalis STE family protein kinase 0.0171 0.0283 0.1281
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Schistosoma mansoni tyrosine kinase 0.0094 0.0067 0.0066
Brugia malayi Tyrosine-protein kinase abl-1 0.0256 0.0519 0.0519
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0029 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0299 0.0638 0.0636
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0467 0.1105 0.1105
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0508 0.459
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0374 0.0846 0.0846
Echinococcus multilocularis tyrosine protein kinase shark 0.0586 0.1434 0.1434
Echinococcus multilocularis mitogen activated protein kinase 14 0.0467 0.1105 0.1105
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0224 0.0431 0.1952
Leishmania major casein kinase, putative 0.0142 0.0201 0.1806
Schistosoma mansoni rap gtpase-activating protein 0.012 0.0141 0.0139
Giardia lamblia Kinase, AGC PKA 0.0193 0.0345 0.1457
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0476 0.0474
Schistosoma mansoni tyrosine kinase 0.0417 0.0967 0.0965
Echinococcus granulosus epidermal growth factor receptor 0.0568 0.1385 0.1385
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0163 0.0261 0.0259
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0275 0.057 0.057
Loa Loa (eye worm) TK/ROR protein kinase 0.009 0.0058 0.0058
Loa Loa (eye worm) thyroid receptor interactor 0.0126 0.0157 0.0157
Leishmania major protein kinase, putative 0.0181 0.0311 0.2803
Trypanosoma cruzi cdc2-related kinase 3 0.0196 0.0351 0.3167
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0243 0.0482 0.0482
Leishmania major protein kinase A catalytic subunit isoform 1 0.0147 0.0214 0.1925
Plasmodium falciparum calcium-dependent protein kinase 4 0.0174 0.0291 0.826
Echinococcus granulosus cyclin dependent kinase 19 0.0201 0.0367 0.0367
Schistosoma mansoni protein kinase 0.0133 0.0176 0.0174
Plasmodium falciparum serine/threonine protein kinase, putative 0.0181 0.0311 0.8852
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0014 0.0012
Schistosoma mansoni tyrosine kinase 0.0519 0.1248 0.1247
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0241 0.0477 0.0477
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0174 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.01 0.0086 0.0086
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0196 0.0351 0.414
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0196 0.0351 0.3167
Trypanosoma cruzi casein kinase, putative 0.0142 0.0201 0.1806
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.0522 0.052
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0127 0.1132
Brugia malayi serine/threonine protein kinase 6 0.0181 0.0311 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0201 0.02
Echinococcus multilocularis tyrosine protein kinase Srms 0.0221 0.0422 0.0422
Schistosoma mansoni tyrosine kinase 0.0508 0.1219 0.1217
Giardia lamblia Kinase, STE STE20 0.0116 0.013 0.0467
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.019 0.0336 0.3024
Echinococcus multilocularis contactin neuroglian septate junction protein 0.007 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0214 0.0402 0.0402
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0257 0.0522 0.0522
Echinococcus granulosus tyrosine protein kinase Src42A 0.0266 0.0545 0.0545
Echinococcus granulosus epidermal growth factor receptor 0.0792 0.2006 0.2006
Entamoeba histolytica protein kinase, putative 0.0163 0.0261 0.2756
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.007 0.0002 0.0002
Plasmodium vivax protein kinase, putative 0.0076 0.0019 0.0477
Brugia malayi cell division control protein 2 homolog 0.0196 0.0351 0.0351
Leishmania major protein kinase, putative 0.0116 0.013 0.1157
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0114 0.0125 0.1458
Trypanosoma cruzi casein kinase, putative 0.0142 0.0201 0.1806
Onchocerca volvulus 0.0522 0.1257 0.4527
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0316 0.0684 0.618
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Loa Loa (eye worm) hypothetical protein 0.0147 0.0214 0.0214
Echinococcus granulosus serine:threonine protein kinase 3 0.0301 0.0644 0.0644
Brugia malayi Protein kinase domain containing protein 0.0232 0.0453 0.0453
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0121 0.0144 0.0144
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0243 0.0482 0.0482
Trypanosoma cruzi p21-activated kinase 3, putative 0.0084 0.004 0.0345
Entamoeba histolytica protein kinase, putative 0.0154 0.0236 0.2492
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0404 0.0929 0.0929
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.022 0.0418 0.3773
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0404 0.0929 0.0929
Brugia malayi Protein kinase domain containing protein 0.0148 0.0218 0.0218
Brugia malayi Protein kinase domain containing protein 0.061 0.1502 0.1502
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0196 0.0351 0.0351
Plasmodium falciparum calcium-dependent protein kinase 5 0.0174 0.0291 0.826
Echinococcus multilocularis epidermal growth factor receptor 0.0568 0.1385 0.1385
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0107 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0298 0.0636 0.0636
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0508 0.459
Echinococcus granulosus activin receptor type 0.0514 0.1236 0.1236
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0458 0.1079 0.1079
Leishmania major developmentally regulated phosphoprotein-like protein 0.0129 0.0165 0.1474
Echinococcus granulosus tyrosine protein kinase Src64B 0.0266 0.0545 0.0545
Schistosoma mansoni serine/threonine protein kinase 0.017 0.028 0.0278
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0113 0.012 0.012
Entamoeba histolytica protein kinase domain containing protein 0.0133 0.0176 0.1849
Echinococcus granulosus nervana 2 0.0133 0.0177 0.0177
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0266 0.0545 0.0545
Echinococcus multilocularis protein tyrosine kinase 0.0604 0.1484 0.1484
Schistosoma mansoni tyrosine kinase 0.0129 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0496 0.1185 0.1185
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0241 0.0477 0.0477
Schistosoma mansoni pyruvate dehydrogenase 0.0129 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0213 0.04 0.04
Schistosoma mansoni tyrosine kinase 0.0529 0.1278 0.1276
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0467 0.1105 1
Loa Loa (eye worm) TK/FER protein kinase 0.0453 0.1065 0.1065
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0174 0.0291 0.0291
Echinococcus granulosus dual specificity 0.0174 0.0292 0.0292
Leishmania major serine/threonine-protein kinase, putative 0.008 0.0029 0.0239
Plasmodium vivax tyrosine kinase-like protein, putative 0.0112 0.0119 0.3342
Schistosoma mansoni protein kinase 0.0419 0.0972 0.097
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0121 0.0144 0.1285
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.01 0.0085 0.0083
Brugia malayi serine/threonine-protein kinase 6 0.0181 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0178 0.0303 0.0303
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0232 0.0453 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0291 0.1314
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0546 0.1324 0.1324
Loa Loa (eye worm) TK/FER protein kinase 0.0127 0.016 0.016
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0127 0.0159 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0848 0.0846
Schistosoma mansoni hypothetical protein 0.011 0.0112 0.011
Loa Loa (eye worm) hypothetical protein 0.0145 0.0211 0.0211
Echinococcus granulosus casein kinase I alpha 0.0142 0.0201 0.0201
Onchocerca volvulus 0.0149 0.0222 0.0696
Plasmodium vivax glycogen synthase kinase 3, putative 0.0163 0.0261 0.7415
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0081 0.0034 0.0284
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0163 0.0261 0.0261
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0214 0.0213
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Onchocerca volvulus 0.1055 0.2737 1
Echinococcus multilocularis epidermal growth factor receptor 0.0792 0.2006 0.2006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Trypanosoma cruzi aurora B kinase, putative 0.0181 0.0311 0.2803
Schistosoma mansoni tyrosine kinase 0.0171 0.0283 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0291 0.0289
Trypanosoma cruzi NIMA-related kinase, putative 0.008 0.0029 0.0239
Echinococcus multilocularis ephrin type A receptor 4 A 0.0129 0.0165 0.0165
Onchocerca volvulus 0.0107 0.0106 0.0268
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0163 0.0261 0.0261
Loa Loa (eye worm) AGC/PKA protein kinase 0.0147 0.0214 0.0214
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0147 0.0214 0.1925
Echinococcus granulosus cyclin dependent kinase 9 0.0109 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0089 0.0054 0.0054
Brugia malayi putative serine/threonine kinase SADA gamma 0.0121 0.0144 0.0144
Entamoeba histolytica protein kinase, putative 0.0114 0.0125 0.1309
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0141 0.126
Loa Loa (eye worm) AGC/PKN protein kinase 0.038 0.0864 0.0864
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0201 0.0367 0.0367
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.019 0.0336 0.3953
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0193 0.0345 0.0345
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0127 0.1132
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0292 0.132
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Schistosoma mansoni tyrosine kinase 0.0568 0.1385 0.1384
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0059 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0101 0.0089 0.0089
Trypanosoma brucei protein kinase, putative 0.0163 0.0261 0.2348
Echinococcus multilocularis casein kinase i 0.0142 0.0201 0.0201
Brugia malayi Protein kinase domain containing protein 0.0201 0.0367 0.0367
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0165 0.0267 0.0267
Onchocerca volvulus 0.0314 0.068 0.239
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0201 0.0367 0.0367
Toxoplasma gondii AGC kinase 0.0147 0.0214 0.2516
Echinococcus granulosus dual specificity 0.0252 0.0508 0.0508
Onchocerca volvulus 0.0127 0.016 0.0467
Brugia malayi Temporarily assigned gene name protein 59 0.012 0.0141 0.0141
Brugia malayi Protein kinase domain containing protein 0.0124 0.0151 0.0151
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0133 0.0176 0.4975
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0249 0.05 0.05
Echinococcus granulosus neuroglian 0.013 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0404 0.0929 0.0928
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0121 0.0144 0.1285
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0029 0.012
Brugia malayi probable protein kinase 0.031 0.0668 0.0668
Echinococcus multilocularis roundabout 2 0.007 0.0002 0.0002
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0121 0.0144 0.0144
Entamoeba histolytica protein kinase , putative 0.0181 0.0311 0.329
Onchocerca volvulus 0.0127 0.016 0.0467
Echinococcus granulosus titin 0.0107 0.0106 0.0106
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0181 0.0311 0.329
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0309 0.0666 0.0666
Brugia malayi Sex muscle abnormal protein 5 0.0111 0.0116 0.0116
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0185 0.0321 0.0321
Loa Loa (eye worm) TK protein kinase 0.0154 0.0236 0.0236
Schistosoma mansoni nephrin 0.0147 0.0215 0.0213
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0159 0.0159
Schistosoma mansoni cell adhesion molecule 0.014 0.0195 0.0193
Schistosoma mansoni pyruvate dehydrogenase 0.0121 0.0145 0.0143
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0225 0.0432 0.0432
Trichomonas vaginalis AGC family protein kinase 0.0384 0.0872 0.3964
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0556 0.1353 0.1353
Entamoeba histolytica casein kinase, putative 0.0133 0.0176 0.1849
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0089 0.0087
Loa Loa (eye worm) TK protein kinase 0.0318 0.0689 0.0689
Entamoeba histolytica protein kinase, putative 0.0101 0.0089 0.0919
Entamoeba histolytica protein kinase, putative 0.0252 0.0508 0.5387
Entamoeba histolytica protein kinase, putative 0.0252 0.0508 0.5387
Leishmania major protein kinase, putative 0.019 0.0336 0.3024
Schistosoma mansoni serine/threonine protein kinase 0.0389 0.0887 0.0885
Schistosoma mansoni titin 0.0107 0.0106 0.0104
Loa Loa (eye worm) hypothetical protein 0.0085 0.0044 0.0044
Entamoeba histolytica protein kinase domain containing protein 0.0252 0.0508 0.5387
Onchocerca volvulus 0.0163 0.0261 0.0842
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0129 0.0165 0.1474
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0181 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.007 0.0002 0.0002
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0149 0.0221 0.0221
Trypanosoma brucei aurora B kinase 0.0181 0.0311 0.2803
Plasmodium falciparum casein kinase 1 0.0142 0.0201 0.5705
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus granulosus casein kinase ii subunit alpha 0.0133 0.0176 0.0176
Schistosoma mansoni serine/threonine-protein kinase 0.0203 0.0371 0.0369
Schistosoma mansoni nck2/grb4 0.0111 0.0116 0.0114
Echinococcus granulosus serine:threonine protein kinase N2 0.0139 0.0195 0.0195
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0257 0.0522 0.0522
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0404 0.0929 0.0929
Echinococcus granulosus tyrosine protein kinase shark 0.0586 0.1434 0.1434
Onchocerca volvulus 0.0142 0.0201 0.0621
Schistosoma mansoni tyrosine kinase 0.0283 0.0593 0.0591
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0163 0.0261 0.2348
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0147 0.0214 0.1925
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0079 0.0028 0.0028
Schistosoma mansoni serine/threonine kinase 0.0241 0.0477 0.0475
Giardia lamblia Kinase, CMGC GSK 0.0163 0.0261 0.1073
Echinococcus multilocularis dual specificity 0.0252 0.0508 0.0508
Leishmania major protein kinase A catalytic subunit 0.0147 0.0214 0.1925
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0104 0.0098 0.0434
Brugia malayi serine/threonine kinase 12 0.0181 0.0311 0.0311
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0258 0.0525 0.0525
Trichomonas vaginalis AGC family protein kinase 0.0113 0.012 0.0538
Trichomonas vaginalis AGC family protein kinase 0.0181 0.0311 0.1408
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0241 0.0476 0.0476
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.065 0.0648
Echinococcus multilocularis casein kinase I alpha 0.0142 0.0201 0.0201
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0508 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.0522 0.052
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0141 0.0139
Echinococcus multilocularis cyclin dependent kinase 7 0.0143 0.0205 0.0205
Entamoeba histolytica cell division protein kinase 2, putative 0.0196 0.0351 0.3716
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0127 0.1132
Trypanosoma brucei cdc2-related kinase 3 0.0196 0.0351 0.3167
Echinococcus multilocularis rac serine:threonine kinase 0.0203 0.0371 0.0371
Schistosoma mansoni tyrosine kinase 0.0273 0.0566 0.0564
Brugia malayi Serine/threonine-protein kinase SULU 0.0467 0.1105 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus granulosus dual specificity 0.0174 0.0292 0.0292
Echinococcus granulosus Protein kinase C brain isozyme 0.0389 0.0887 0.0887
Entamoeba histolytica protein kinase domain containing protein 0.0243 0.0482 0.5104
Loa Loa (eye worm) TK protein kinase 0.0303 0.0649 0.0649
Brugia malayi protein unc-22 0.0107 0.0106 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0127 0.0569
Loa Loa (eye worm) hypothetical protein 0.011 0.0112 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0223 0.0426 0.0426
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1038 0.2688 0.2688
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0266 0.0545 0.0545
Brugia malayi serine/threonine-protein kinase plk-2 0.0316 0.0684 0.0684
Echinococcus granulosus c src tyrosine kinase 0.0171 0.0283 0.0283
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0149 0.0222 0.0222
Echinococcus multilocularis serine:threonine protein kinase 0.0148 0.0218 0.0218
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0144 0.0646
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0129 0.0165 0.0165
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0257 0.0522 0.0522
Echinococcus multilocularis c src tyrosine kinase 0.0171 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0153 0.0232 0.0232
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0127 0.0454
Loa Loa (eye worm) AGC/PKG protein kinase 0.017 0.0279 0.0279
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0185 0.0321 0.0321
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.009 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0111 0.0116 0.0116
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0331 0.0728 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0336 0.0334
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.008 0.0029 0.0239
Brugia malayi casein kinase I 0.0142 0.0201 0.0201
Brugia malayi P38 map kinase family protein 2 0.0467 0.1105 0.1105
Echinococcus granulosus serine:threonine protein kinase 0.0148 0.0218 0.0218
Echinococcus granulosus Glutaredoxin protein 5 0.0133 0.0177 0.0177
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0404 0.0929 0.0929
Leishmania major protein kinase, putative 0.0174 0.0291 0.2615
Echinococcus multilocularis nervana 2 0.0133 0.0177 0.0177
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0274 0.0567 0.0567
Toxoplasma gondii NEK kinase 0.008 0.0029 0.0312
Echinococcus multilocularis protein kinase c iota type 0.039 0.089 0.089
Entamoeba histolytica protein kinase, putative 0.0174 0.0292 0.3083
Onchocerca volvulus 0.0298 0.0636 0.2229
Schistosoma mansoni growth factor receptor-bound protein 0.0111 0.0116 0.0114
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0133 0.0176 0.0176
Brugia malayi casein kinase 1, delta 0.0142 0.0201 0.0201
Plasmodium falciparum protein kinase, putative 0.012 0.0142 0.3994
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0279 0.0279
Trypanosoma cruzi cdc2-related kinase 3 0.0196 0.0351 0.3167
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Brugia malayi Protein kinase domain containing protein 0.0529 0.1278 0.1278
Echinococcus granulosus aurora kinase A 0.0181 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0089 0.0054 0.0054
Echinococcus granulosus tyrosine protein kinase Fyn 0.0266 0.0545 0.0545
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.009 0.0058 0.0058
Echinococcus multilocularis calcium activated potassium channel 0.017 0.028 0.028
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0419 0.0972 0.0972
Trichomonas vaginalis AGC family protein kinase 0.0114 0.0124 0.0556
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0453 0.1065 0.1065
Echinococcus multilocularis casein kinase I gamma 0.0254 0.0514 0.0514
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.012 0.0142 0.1654
Loa Loa (eye worm) hypothetical protein 0.0522 0.1257 0.1257
Trypanosoma cruzi casein kinase, putative 0.0142 0.0201 0.1806
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.008 0.0029 0.0239
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0273 0.0566 0.0566
Brugia malayi Protein kinase domain containing protein 0.0127 0.016 0.016
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0199 0.0359 0.0359
Schistosoma mansoni protein kinase C mu 0.0274 0.0567 0.0566
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0098 0.0434
Toxoplasma gondii NEK kinase 0.008 0.0029 0.0312
Trichomonas vaginalis STE family protein kinase 0.022 0.0418 0.1895
Onchocerca volvulus 0.012 0.0141 0.0398
Echinococcus granulosus activated cdc42 kinase 1 0.0238 0.0469 0.0469
Echinococcus granulosus growth factor receptor bound protein 2 0.0115 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0121 0.0144 0.0144
Onchocerca volvulus Tyrosine kinase homolog 0.0612 0.1507 0.5452
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.008 0.0029 0.0754
Brugia malayi SH2 domain containing protein 0.0453 0.1065 0.1065
Schistosoma mansoni protein kinase 0.022 0.0418 0.0416
Entamoeba histolytica protein kinase, putative 0.0127 0.0162 0.1695
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0684 0.3104
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0147 0.0214 0.0214
Trichomonas vaginalis CK1 family protein kinase 0.0142 0.0201 0.0908
Echinococcus granulosus protein kinase 0.019 0.0334 0.0334
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1371 0.3615 0.3615
Echinococcus multilocularis serine:threonine protein kinase N2 0.0139 0.0195 0.0195
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0221 0.0422 0.0422
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0196 0.0351 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.0707 0.3212
Brugia malayi cyclin-dependent kinase 9 0.0109 0.011 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0174 0.0292 0.3083
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0109 0.011 0.011
Loa Loa (eye worm) CDC7 protein kinase 0.0861 0.2198 0.2198
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0127 0.016 0.1678
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0728 0.0726
Echinococcus granulosus tyrosine protein kinase Src42A 0.0165 0.0267 0.0267
Brugia malayi Egg laying defective protein 4 0.017 0.0279 0.0279
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0127 0.0162 0.1695
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0303 0.065 0.065
Echinococcus multilocularis casein kinase I delta 0.0142 0.0201 0.0201
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0432 0.1006 0.1006
Loa Loa (eye worm) hypothetical protein 0.0249 0.05 0.05
Entamoeba histolytica protein kinase, putative 0.0104 0.0096 0.0996
Giardia lamblia Kinase, CMGC DYRK 0.0174 0.0292 0.1214
Brugia malayi Protein kinase domain containing protein 0.0318 0.0689 0.0689
Echinococcus multilocularis roundabout 2 0.007 0.0002 0.0002
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0147 0.0214 0.1925
Trichomonas vaginalis AGC family protein kinase 0.0121 0.0144 0.0646
Schistosoma mansoni serine/threonine kinase 0.0267 0.0548 0.0547
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0316 0.0684 0.0684

Activities

Activity type Activity value Assay description Source Reference
log K = 2.09 Octanol-water partition coefficient, log Kow of the compound ChEMBL. 17481907
logKA (ADMET) = 0.031 Binding affinity to human serum albumin ChEMBL. 17481907
logKA (ADMET) = 0.031 Binding affinity to human serum albumin ChEMBL. 17481907

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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