Detailed information for compound 511637

Basic information

Technical information
  • TDR Targets ID: 511637
  • Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3- hydroxy-3-phenylprop-1-ynyl]-6-(propan-2-ylam ino)purin-9-yl]oxolane-3,4-diol
  • MW: 439.464 | Formula: C22H25N5O5
  • H donors: 5 H acceptors: 7 LogP: 0.8 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(C#C[C@H](c1ccccc1)O)nc2NC(C)C
  • InChi: 1S/C22H25N5O5/c1-12(2)24-20-17-21(27(11-23-17)22-19(31)18(30)15(10-28)32-22)26-16(25-20)9-8-14(29)13-6-4-3-5-7-13/h3-7,11-12,14-15,18-19,22,28-31H,10H2,1-2H3,(H,24,25,26)/t14-,15-,18-,19-,22-/m1/s1
  • InChiKey: YLEPHVZVZULFSJ-VACFCZKPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenyl-prop-1-ynyl]-6-(isopropylamino)purin-9-yl]tetrahydrofuran-3,4-diol
  • (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]-6-(isopropylamino)-9-purinyl]tetrahydrofuran-3,4-diol
  • (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenyl-prop-1-ynyl]-6-(propan-2-ylamino)purin-9-yl]oxolane-3,4-diol
  • (2R,3R,4S,5R)-2-[2-[(3S)-3-hydroxy-3-phenyl-prop-1-ynyl]-6-(isopropylamino)purin-9-yl]-5-methylol-tetrahydrofuran-3,4-diol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosine A3 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2a receptor Starlite/ChEMBL References
Homo sapiens adenosine A1 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2b receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi hypothetical protein adenosine A1 receptor 326 aa 305 aa 21.0 %
Brugia malayi follicle stimulating hormone receptor adenosine A2a receptor 412 aa 336 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase HCK 0.0303 0.1824 0.1819
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0241 0.0488
Echinococcus multilocularis SH2 motif 0.0463 0.2859 0.2854
Schistosoma mansoni hypothetical protein 0.0026 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Brugia malayi follicle stimulating hormone receptor 0.0282 0.1686 0.349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0147 0.0415
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0303 0.1824 0.1819
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0463 0.2859 0.2854
Echinococcus granulosus slit 2 protein 0.0077 0.0362 0.0356
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0091 0.045 0.2057
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0058 0.0241 0.0235
Echinococcus multilocularis tubulin subunit TubB 0.0284 0.17 0.1695
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Echinococcus granulosus tubulin beta 4A class IVa 0.0347 0.2105 0.21
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Echinococcus multilocularis tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) TK/INSR protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni bromodomain containing protein 0.0078 0.0369 0.0363
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Echinococcus granulosus suppressor of cytokine signaling 6 0.0463 0.2859 0.2854
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus tyrosine kinase 0.0766 0.4819 0.4816
Echinococcus multilocularis peroxisome assembly protein 26 0.0284 0.17 0.1695
Mycobacterium ulcerans cell division protein FtsZ 0.0091 0.045 0.5915
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0006 0.003
Echinococcus multilocularis expressed conserved protein 0.0106 0.0548 0.0542
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0303 0.1824 0.865
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Brugia malayi ecdysone receptor 0.0025 0.0023 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0303 0.1824 0.1819
Giardia lamblia Kinase 0.0303 0.1824 0.866
Toxoplasma gondii protein kinase domain-containing protein 0.0303 0.1824 0.865
Trichomonas vaginalis tubulin, putative 0.0091 0.045 0.1303
Schistosoma mansoni shc transforming protein 0.0463 0.2859 0.2854
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Brugia malayi hypothetical protein 0.0037 0.0104 0.0204
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0282 0.1686 0.349
Loa Loa (eye worm) animal heme peroxidase 0.0597 0.3721 0.7719
Loa Loa (eye worm) TK/EPH protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Echinococcus granulosus tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Schistosoma mansoni zinc finger protein 0.0027 0.0039 0.0032
Loa Loa (eye worm) tubulin beta-2A chain 0.0347 0.2105 0.4361
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0303 0.1824 0.3777
Echinococcus granulosus Tubulin beta 2C chain 0.0347 0.2105 0.21
Echinococcus granulosus tyrosine protein kinase pr2 0.0303 0.1824 0.1819
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0023 0.0017
Plasmodium vivax tubulin alpha chain, putative 0.0284 0.17 0.8058
Echinococcus multilocularis tubulin alpha 3 chain 0.0284 0.17 0.1695
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0487
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0133 0.0373
Echinococcus granulosus lamin 0.009 0.0444 0.0437
Brugia malayi jmjC domain containing protein 0.0071 0.0323 0.0657
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0463 0.2859 0.2854
Onchocerca volvulus 0.0086 0.0422 0.0851
Onchocerca volvulus Slit protein homolog 0.0077 0.0362 0.0727
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0303 0.1824 0.1819
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0303 0.1824 0.1819
Brugia malayi tailless protein 0.0025 0.0023 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0176 0.0499
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Brugia malayi CHE-14 protein 0.0048 0.0176 0.0353
Onchocerca volvulus Cell death protein 3 homolog 0.0069 0.0309 0.0616
Brugia malayi hypothetical protein 0.0139 0.0764 0.1574
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Echinococcus granulosus tumor protein p63 0.0386 0.2362 0.2358
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0303 0.1824 0.3777
Schistosoma mansoni tubulin subunit alpha 0.0284 0.17 0.1695
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0172 0.0978 0.0972
Echinococcus granulosus expressed conserved protein 0.0463 0.2859 0.2854
Brugia malayi Animal haem peroxidase family protein 0.0597 0.3721 0.7719
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0091 0.045 0.1303
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.0592 0.0586
Echinococcus multilocularis Tubulin beta 2C chain 0.0347 0.2105 0.21
Echinococcus granulosus zinc finger protein 0.0027 0.0039 0.0032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.0294 0.0287
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Schistosoma mansoni lamin 0.009 0.0444 0.0437
Echinococcus granulosus Tubulin alpha 1 chain 0.0284 0.17 0.1695
Echinococcus granulosus activated cdc42 kinase 1 0.0303 0.1824 0.1819
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0054 0.0214 0.0208
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0043 0.0142 0.2825
Brugia malayi hypothetical protein 0.0025 0.0023 0.0035
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0303 0.1824 0.5346
Giardia lamblia Beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0398 0.0814
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0214 0.0208
Brugia malayi Variant SH3 domain containing protein 0.0463 0.2859 0.5927
Echinococcus multilocularis tubulin alpha chain 0.0284 0.17 0.1695
Echinococcus granulosus histone acetyltransferase KAT2B 0.0053 0.0204 0.0198
Echinococcus multilocularis heat shock protein 70 0.0303 0.1824 0.1819
Echinococcus multilocularis growth factor receptor bound protein 2 0.0463 0.2859 0.2854
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0463 0.2859 0.2854
Plasmodium vivax protein kinase, putative 0.0303 0.1824 0.865
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Leishmania major cytochrome p450-like protein 0.0049 0.0181 0.0857
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0136 0.027
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0013
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0054 0.0214 0.0208
Brugia malayi protein-tyrosine kinase 0.0766 0.4819 1
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) tubulin alpha 2 0.0193 0.1115 0.2303
Toxoplasma gondii exonuclease III APE 0.0043 0.0142 0.0581
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Echinococcus multilocularis lamin 0.009 0.0444 0.0437
Leishmania major beta tubulin 0.0347 0.2105 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0053 0.0204 0.088
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0133 0.0604
Schistosoma mansoni hypothetical protein 0.0047 0.0165 0.0159
Brugia malayi Tubulin alpha-2 chain 0.0284 0.17 0.352
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Onchocerca volvulus 0.0303 0.1824 0.3768
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Leishmania major beta tubulin 0.0347 0.2105 1
Schistosoma mansoni peroxidasin 0.0597 0.3721 0.3717
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0021 0.009
Echinococcus multilocularis tubulin alpha chain 0.0284 0.17 0.1695
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0303 0.1824 0.3777
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0023 0.0022
Brugia malayi Delta serrate ligand family protein 0.0077 0.0362 0.0739
Giardia lamblia Kinase, CMGC MAPK 0.0117 0.0617 0.2911
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0133 0.0624
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0058 0.0241 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0087 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Loa Loa (eye worm) animal heme peroxidase 0.0597 0.3721 0.7719
Echinococcus multilocularis epidermal growth factor receptor 0.0303 0.1824 0.1819
Schistosoma mansoni hypothetical protein 0.0059 0.0246 0.024
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Loa Loa (eye worm) hypothetical protein 0.027 0.1612 0.3337
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0308 0.0302
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Onchocerca volvulus 0.009 0.0444 0.0896
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0082 0.0075
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Entamoeba histolytica receptor protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0236 0.1096
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/ABL protein kinase 0.0766 0.4819 1
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0058 0.0241 0.0235
Echinococcus granulosus activin receptor type 0.0304 0.1831 0.1826
Entamoeba histolytica tubulin alpha chain, putative 0.0284 0.17 0.352
Loa Loa (eye worm) hypothetical protein 0.0766 0.4819 1
Schistosoma mansoni tubulin subunit beta 0.0091 0.045 0.0443
Trichomonas vaginalis tubulin gamma chain, putative 0.0347 0.2105 0.6174
Echinococcus granulosus insulin receptor 0.0303 0.1824 0.1819
Echinococcus granulosus alpha tubulin 0.0284 0.17 0.1695
Echinococcus granulosus tubulin alpha chain 0.0284 0.17 0.1695
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0082 0.0075
Trichomonas vaginalis tubulin epsilon chain, putative 0.0284 0.17 0.4983
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0766 0.4819 0.4816
Leishmania major beta tubulin 0.0347 0.2105 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0096 0.0485 0.0479
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Onchocerca volvulus 0.0548 0.3406 0.706
Onchocerca volvulus 0.0025 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.006 0.0159
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) DR-78 0.0025 0.0023 0.0035
Plasmodium vivax delta tubulin, putative 0.0091 0.045 0.2057
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Entamoeba histolytica protein kinase, putative 0.0464 0.2866 0.5941
Schistosoma mansoni hypothetical protein 0.004 0.0121 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0088 0.043 0.9564
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.009 0.0444 0.0908
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0303 0.1824 0.865
Brugia malayi hypothetical protein 0.0157 0.0878 0.1811
Echinococcus granulosus tubulin alpha chain 0.0284 0.17 0.1695
Leishmania major epsilon tubulin, putative 0.0209 0.1213 0.5761
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0241 0.0235
Loa Loa (eye worm) hypothetical protein 0.0093 0.0468 0.0958
Trypanosoma brucei PAB1-binding protein , putative 0.0058 0.0236 0.1116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0091 0.045 0.1303
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0034 0.0028
Schistosoma mansoni coup transcription factor 0.0058 0.0241 0.0235
Schistosoma mansoni slit 0.0077 0.0362 0.0356
Echinococcus multilocularis receptor type guanylyl cyclase 0.0303 0.1824 0.1819
Brugia malayi hypoxia-induced factor 1 0.0172 0.0977 0.2017
Onchocerca volvulus 0.0463 0.2859 0.5921
Echinococcus multilocularis tubulin alpha chain 0.0284 0.17 0.1695
Leishmania major beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0303 0.1824 0.3777
Trypanosoma cruzi epsilon tubulin, putative 0.0209 0.1213 0.5749
Leishmania major beta tubulin 0.0347 0.2105 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.0223 0.0217
Giardia lamblia Delta tubulin 0.0091 0.045 0.2111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.0756 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0181 0.0362
Echinococcus granulosus tyrosine protein kinase Src42A 0.0766 0.4819 0.4816
Echinococcus multilocularis Tubulin alpha 1 chain 0.0284 0.17 0.1695
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Plasmodium falciparum tyrosine kinase-like protein 0.0303 0.1824 0.865
Loa Loa (eye worm) intermediate filament protein 0.009 0.0444 0.0908
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0023 0.0035
Leishmania major hypothetical protein, conserved 0.0058 0.0236 0.1123
Brugia malayi Calcium binding EGF domain containing protein 0.0077 0.0362 0.0739
Trichomonas vaginalis tubulin epsilon chain, putative 0.0347 0.2105 0.6174
Echinococcus granulosus epidermal growth factor receptor 0.0303 0.1824 0.1819
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0241 0.0488
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0241 0.0235
Plasmodium vivax tubulin alpha chain, putative 0.0284 0.17 0.8058
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0463 0.2859 0.5927
Leishmania major beta tubulin 0.0347 0.2105 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0617 0.2911
Trypanosoma brucei epsilon tubulin 0.0209 0.1213 0.5758
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Onchocerca volvulus 0.0303 0.1824 0.3768
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0013
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0133 0.0604
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0766 0.4819 0.4816
Loa Loa (eye worm) tubulin alpha chain 0.0284 0.17 0.352
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0303 0.1824 0.1819
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0303 0.1824 0.1819
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0117 0.0617 0.1269
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Schistosoma mansoni vav2 0.0463 0.2859 0.2854
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.031 0.0304
Schistosoma mansoni growth factor receptor-bound protein 0.0463 0.2859 0.2854
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0172 0.0978 0.0972
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Entamoeba histolytica hypothetical protein 0.012 0.0637 0.1311
Plasmodium falciparum tubulin beta chain 0.0347 0.2105 1
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0117 0.0617 0.2862
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi Tubulin beta chain 0.0118 0.0627 0.129
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.1824 0.1819
Brugia malayi nuclear hormone receptor 0.0025 0.0023 0.0035
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0303 0.1824 0.1819
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus granulosus tubulin gamma 1 chain 0.0209 0.1213 0.1207
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) beta-tubulin 0.0347 0.2105 0.4361
Brugia malayi Furin-like cysteine rich region family protein 0.0303 0.1824 0.3777
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0043 0.0142 0.1808
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Echinococcus multilocularis signal transduction protein lnk realted 0.0463 0.2859 0.2854
Schistosoma mansoni suppressor of cytokine signaling 0.0463 0.2859 0.2854
Plasmodium falciparum tubulin gamma chain 0.0209 0.1213 0.5719
Loa Loa (eye worm) hypothetical protein 0.0363 0.221 0.4578
Echinococcus multilocularis tubulin alpha chain 0.0284 0.17 0.1695
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Schistosoma mansoni tubulin subunit delta 0.0091 0.045 0.0443
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0043 0.0142 0.0666
Toxoplasma gondii isocitrate dehydrogenase 0.0054 0.0214 0.0928
Onchocerca volvulus 0.0766 0.4819 1
Loa Loa (eye worm) alpha-tubulin 0.0284 0.17 0.352
Schistosoma mansoni tubulin subunit alpha 0.0091 0.045 0.0443
Entamoeba histolytica tyrosin kinase, putative 0.0303 0.1824 0.3777
Brugia malayi intermediate filament protein 0.009 0.0444 0.0908
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0439 0.0433
Leishmania major zeta tubulin, putative 0.0091 0.045 0.2135
Onchocerca volvulus 0.0766 0.4819 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni hypothetical protein 0.0048 0.0175 0.0169
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trichomonas vaginalis AGC family protein kinase 0.0303 0.1824 0.5346
Leishmania major beta tubulin 0.0347 0.2105 1
Schistosoma mansoni hypothetical protein 0.012 0.0637 0.0631
Giardia lamblia GTOR 0.0051 0.0196 0.0903
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0058 0.0241 0.0488
Trypanosoma cruzi tubulin delta chain 0.0091 0.045 0.2111
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0303 0.1824 0.1819
Echinococcus multilocularis Niemann Pick C1 protein 0.0161 0.0904 0.0898
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Onchocerca volvulus 0.0075 0.0351 0.0704
Echinococcus multilocularis neurogenic locus notch protein 4 0.0077 0.0362 0.0356
Trypanosoma brucei Pseudokinase, putative 0.0303 0.1824 0.8663
Trypanosoma cruzi epsilon tubulin, putative 0.0209 0.1213 0.5749
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0196 0.019
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Brugia malayi Isocitrate dehydrogenase 0.0054 0.0214 0.0432
Brugia malayi hypothetical protein 0.0766 0.4819 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica tubulin gamma chain 0.0209 0.1213 0.2507
Schistosoma mansoni septate junction protein 0.0077 0.0362 0.0356
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0021 0.0182
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0463 0.2859 0.2854
Brugia malayi hypothetical protein 0.012 0.0637 0.1311
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus NCK adaptor protein 0.0463 0.2859 0.2854
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0088 0.043 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) tubulin alpha-3 chain 0.0166 0.0937 0.1934
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0463 0.2859 0.2854
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0128 0.0609
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0006 0.0022
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Schistosoma mansoni aldehyde dehydrogenase 0.0138 0.0756 0.075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0135 0.0129
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0118 0.0627 0.1826
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0091 0.045 1
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Schistosoma mansoni survival motor neuron protein 0.0055 0.022 0.0214
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0463 0.2859 0.5927
Onchocerca volvulus 0.0303 0.1824 0.3768
Echinococcus multilocularis neurogenic locus protein delta 0.0077 0.0362 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0157
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus multilocularis Tubulin beta 2C chain 0.0347 0.2105 0.21
Echinococcus granulosus N chimaerin 0.0463 0.2859 0.2854
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0023 0.0017
Echinococcus granulosus tubulin alpha 1C chain 0.0284 0.17 0.1695
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0463 0.2859 0.2854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0062 0.0164
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Entamoeba histolytica cysteine surface protein, putative 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi Muscle positioning protein 4 0.0077 0.0362 0.0739
Treponema pallidum cell division protein FtsZ 0.0091 0.045 1
Echinococcus granulosus tubulin alpha chain 0.0284 0.17 0.1695
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0058 0.0241 0.0235
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0091 0.045 0.2057
Echinococcus multilocularis fibropellin Ia 0.0077 0.0362 0.0356
Brugia malayi tRNA modification GTPase TrmE family protein 0.0463 0.2859 0.5927
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0236 0.1096
Echinococcus granulosus Tubulin alpha 1 chain 0.0284 0.17 0.1695
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0196 0.0931
Brugia malayi Cytochrome P450 family protein 0.0049 0.0181 0.0362
Giardia lamblia Gamma tubulin 0.0209 0.1213 0.5749
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0023 0.0017
Loa Loa (eye worm) transcription factor SMAD2 0.026 0.1548 0.3203
Brugia malayi Calcium binding EGF domain containing protein 0.0077 0.0362 0.0739
Echinococcus granulosus protein jagged 1 0.0077 0.0362 0.0356
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus multilocularis protein kinase 0.0303 0.1824 0.1819
Toxoplasma gondii endonuclease IV APN 0.0088 0.043 0.1966
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus granulosus neurogenic locus notch protein 0.0077 0.0362 0.0356
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0303 0.1824 0.3777
Echinococcus multilocularis epidermal growth factor receptor 0.0303 0.1824 0.1819
Trypanosoma brucei beta tubulin 0.0347 0.2105 1
Schistosoma mansoni hypothetical protein 0.0047 0.0165 0.0159
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trypanosoma brucei alpha tubulin, putative 0.0118 0.0627 0.2973
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0023 0.0022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0241 0.0487
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0303 0.1824 0.3768
Entamoeba histolytica receptor protein kinase, putative 0.0303 0.1824 0.3777
Schistosoma mansoni tensin-related 0.0463 0.2859 0.2854
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0463 0.2859 0.2854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0358
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis NCK adaptor protein 0.0463 0.2859 0.2854
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0138 0.0756 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0043 0.0142 0.0645
Schistosoma mansoni ap endonuclease 0.0043 0.0142 0.0136
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.006 0.0159
Echinococcus granulosus kinase suppressor of Ras 1 0.0303 0.1824 0.1819
Echinococcus multilocularis tensin 0.0463 0.2859 0.2854
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Onchocerca volvulus Bile acid receptor homolog 0.0058 0.0241 0.0475
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Onchocerca volvulus 0.0463 0.2859 0.5921
Echinococcus granulosus neurogenic locus notch protein 0.0077 0.0362 0.0356
Echinococcus granulosus caspase 2 0.0069 0.0309 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.031 0.0304
Trypanosoma brucei alpha tubulin 0.0284 0.17 0.8075
Entamoeba histolytica ankyrin repeat protein 0.0303 0.1824 0.3777
Trypanosoma cruzi tubulin gamma chain 0.0209 0.1213 0.5749
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0157
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0214 0.0208
Loa Loa (eye worm) hypothetical protein 0.0088 0.043 0.0881
Trichomonas vaginalis protein kinase atn1, putative 0.0303 0.1824 0.5346
Echinococcus multilocularis activated cdc42 kinase 1 0.0303 0.1824 0.1819
Schistosoma mansoni tubulin subunit gamma 0.0209 0.1213 0.1207
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0082 0.0157
Leishmania major beta tubulin 0.0347 0.2105 1
Onchocerca volvulus Tyrosine kinase homolog 0.0303 0.1824 0.3768
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Echinococcus multilocularis tubulin alpha 3 chain 0.0284 0.17 0.1695
Brugia malayi Cell death protein 3 precursor 0.0069 0.0309 0.0629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0048 0.0174 0.0349
Plasmodium falciparum tubulin epsilon chain, putative 0.0209 0.1213 0.5719
Schistosoma mansoni laminin gamma-3 chain 0.0077 0.0362 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Entamoeba histolytica hypothetical protein, conserved 0.0303 0.1824 0.3777
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0043 0.0142 0.0674
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0766 0.4819 0.4816
Brugia malayi integrin-linked kinase 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0463 0.2859 0.2854
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0766 0.4819 0.4816
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0422 0.0416
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis protein tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus granulosus tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Brugia malayi ephrin receptor 1 precursor 0.0303 0.1824 0.3777
Echinococcus granulosus mitogen activated protein kinase 0.0117 0.0617 0.0611
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.1824 0.1819
Onchocerca volvulus 0.0303 0.1824 0.3768
Plasmodium vivax tubulin gamma chain, putative 0.0209 0.1213 0.5719
Loa Loa (eye worm) TK/ALK protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0358
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0463 0.2859 0.2854
Trypanosoma cruzi zeta tubulin, putative 0.0091 0.045 0.2111
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0308 0.0302
Echinococcus granulosus growth factor receptor bound protein 2 0.0463 0.2859 0.2854
Onchocerca volvulus 0.0597 0.3721 0.7716
Brugia malayi STAT protein, DNA binding domain containing protein 0.0463 0.2859 0.5927
Onchocerca volvulus 0.0077 0.0362 0.0727
Leishmania major beta tubulin 0.0347 0.2105 1
Leishmania major beta tubulin 0.0347 0.2105 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0214 0.1017
Brugia malayi Peroxidasin 0.0597 0.3721 0.7719
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0263
Leishmania major beta tubulin 0.0347 0.2105 1
Echinococcus granulosus Tubulin beta 2C chain 0.0347 0.2105 0.21
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0303 0.1824 0.1819
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0463 0.2859 0.5927
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) pax transcription factor protein 2 0.0275 0.1643 0.3402
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus tyrosine protein kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0166 0.0937 0.1934
Leishmania major hypothetical protein, conserved 0.0303 0.1824 0.8664
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Mycobacterium ulcerans endonuclease IV 0.0088 0.043 0.5661
Toxoplasma gondii STE kinase 0.0303 0.1824 0.865
Schistosoma mansoni alpha tubulin 0.0284 0.17 0.1695
Echinococcus multilocularis protein KINase family member (kin 25) 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Onchocerca volvulus 0.0077 0.0362 0.0727
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Giardia lamblia Alpha-tubulin 0.0284 0.17 0.8071
Echinococcus granulosus beta tubulin 0.0347 0.2105 0.21
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Echinococcus multilocularis transfer RNA-Thr 0.0303 0.1824 0.1819
Brugia malayi Intermediate filament tail domain containing protein 0.009 0.0444 0.0908
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0241 0.0235
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0463 0.2859 0.5927
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0058 0.0241 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0159 0.0665
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Trypanosoma brucei zeta tubulin, putative 0.0091 0.045 0.2129
Echinococcus granulosus tubulin subunit TubB 0.0284 0.17 0.1695
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Echinococcus multilocularis activin receptor type 0.0304 0.1831 0.1826
Echinococcus granulosus jun protein 0.0096 0.0485 0.0479
Schistosoma mansoni hypothetical protein 0.0303 0.1824 0.1819
Trypanosoma cruzi beta tubulin, putative 0.0347 0.2105 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0054 0.0214 0.0928
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0181 0.0362
Echinococcus multilocularis tubulin gamma 1 chain 0.0209 0.1213 0.1207
Echinococcus multilocularis tyrosine protein kinase HCK 0.0303 0.1824 0.1819
Echinococcus multilocularis mitogen activated protein kinase 3 0.0117 0.0617 0.0611
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.043 0.1966
Trichomonas vaginalis tubulin, putative 0.0118 0.0627 0.1826
Schistosoma mansoni protein kinase 0.0304 0.1831 0.1826
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0023 0.0017
Echinococcus granulosus SH2 domain containing protein 7 0.0463 0.2859 0.2854
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0304 0.1831 0.8692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0082 0.0075
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0023 0.0017
Entamoeba histolytica hypothetical protein 0.012 0.0637 0.1311
Trypanosoma brucei zeta tubulin 0.0091 0.045 0.2129
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0196 0.0924
Schistosoma mansoni hypothetical protein 0.0055 0.022 0.0214
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.0603 0.0597
Brugia malayi steroid hormone receptor 0.0058 0.0241 0.0488
Schistosoma mansoni peroxidasin 0.0597 0.3721 0.3717
Echinococcus multilocularis protein kinase 0.0303 0.1824 0.1819
Plasmodium falciparum protein kinase, putative 0.0304 0.1831 0.8683
Trichomonas vaginalis tubulin epsilon chain, putative 0.0347 0.2105 0.6174
Trypanosoma brucei alpha tubulin 0.0284 0.17 0.8075
Plasmodium vivax ataxin-2 like protein, putative 0.0058 0.0236 0.1035
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni protein tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Trypanosoma brucei epsilon tubulin 0.0209 0.1213 0.5758
Plasmodium falciparum tyrosine kinase-like protein 0.0303 0.1824 0.865
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Schistosoma mansoni ephrin receptor 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0052 0.0198 0.0399
Trypanosoma cruzi protein kinase, putative 0.0303 0.1824 0.866
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0196 0.0903
Trichomonas vaginalis tubulin beta chain, putative 0.0118 0.0627 0.1826
Brugia malayi Tubulin alpha chain 0.0091 0.045 0.0921
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0058 0.0241 0.0235
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0133 0.0373
Onchocerca volvulus 0.0048 0.0175 0.0338
Echinococcus multilocularis Tubulin beta 2C chain 0.0347 0.2105 0.21
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0439 0.0433
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0766 0.4819 0.4816
Onchocerca volvulus Peroxidasin homolog 0.0597 0.3721 0.7716
Mycobacterium leprae cell division protein FtsZ 0.0091 0.045 1
Echinococcus granulosus protein kinase 0.0303 0.1824 0.1819
Giardia lamblia Beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0154 0.0306
Echinococcus multilocularis neuropeptide receptor A26 0.0545 0.3387 0.3383
Brugia malayi MAP kinase sur-1 0.0117 0.0617 0.1269
Onchocerca volvulus 0.0463 0.2859 0.5921
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0159 0.0728
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0463 0.2859 0.2854
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0121 0.0239
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0229 0.0223
Brugia malayi nuclear receptor NHR-88 0.0058 0.0241 0.0488
Trichomonas vaginalis protein tyrosine kinase, putative 0.0303 0.1824 0.5346
Plasmodium vivax tyrosine kinase-like protein, putative 0.0303 0.1824 0.865
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Echinococcus multilocularis beta tubulin 0.0347 0.2105 0.21
Echinococcus multilocularis tubulin beta 1 chain 0.0347 0.2105 0.21
Echinococcus multilocularis Tubulin beta 2C chain 0.0347 0.2105 0.21
Schistosoma mansoni tubulin subunit alpha 0.0284 0.17 0.1695
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus tubulin beta 1 chain 0.0347 0.2105 0.21
Toxoplasma gondii isocitrate dehydrogenase 0.0054 0.0214 0.0928
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus multilocularis neuropeptide s receptor 0.0545 0.3387 0.3383
Echinococcus multilocularis tubulin alpha 1C chain 0.0284 0.17 0.1695
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0304 0.1831 0.8683
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0021 0.0191
Echinococcus granulosus ephrin type A receptor 4 A 0.0303 0.1824 0.1819
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi hypothetical protein 0.027 0.1612 0.3337
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi nuclear hormone receptor 0.0058 0.0241 0.0488
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0766 0.4819 0.4816
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0303 0.1824 0.5346
Echinococcus multilocularis tyrosine protein kinase csk 0.0303 0.1824 0.1819
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) isocitrate dehydrogenase 0.0054 0.0214 0.0432
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.0592 0.1216
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0043 0.0142 0.1808
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0053 0.0204 0.088
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0181 0.085
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) animal heme peroxidase 0.0597 0.3721 0.7719
Loa Loa (eye worm) hypothetical protein 0.0086 0.0422 0.0863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0062 0.0164
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Loa Loa (eye worm) tubulin beta chain 0.0347 0.2105 0.4361
Onchocerca volvulus Peroxidase homolog 0.0597 0.3721 0.7716
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0236 0.1035
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0021 0.0091
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0054 0.0214 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0241 0.0235
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0463 0.2859 0.2854
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Brugia malayi beta-tubulin, identical 0.0347 0.2105 0.4361
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0766 0.4819 0.4816
Schistosoma mansoni nuclear receptor 0.0025 0.0023 0.0017
Echinococcus multilocularis microtubule associated protein 2 0.1567 1 1
Echinococcus multilocularis protein jagged 1 0.0077 0.0362 0.0356
Schistosoma mansoni tyrosine protein kinase 0.0303 0.1824 0.1819
Schistosoma mansoni hypothetical protein 0.0586 0.3651 0.3647
Entamoeba histolytica hypothetical protein 0.012 0.0637 0.1311
Echinococcus multilocularis FTZ F1 alpha 0.0058 0.0241 0.0235
Onchocerca volvulus 0.0077 0.0362 0.0727
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Loa Loa (eye worm) hypothetical protein 0.0037 0.01 0.0195
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Schistosoma mansoni intermediate filament proteins 0.009 0.0444 0.0437
Brugia malayi Pre-SET motif family protein 0.0069 0.031 0.0631
Echinococcus multilocularis tubulin subunit beta 0.0347 0.2105 0.21
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0304 0.1831 0.8692
Brugia malayi hypothetical protein 0.0034 0.0082 0.0157
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi tubulin alpha chain - mouse 0.0284 0.17 0.352
Brugia malayi Protein kinase domain containing protein 0.0766 0.4819 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0284 0.17 0.1695
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0023 0.0017
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0054 0.0214 0.2774
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0463 0.2859 0.2854
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0181 0.2324
Echinococcus granulosus tyrosine protein kinase ABL1 0.0766 0.4819 0.4816
Plasmodium falciparum alpha tubulin 2 0.0284 0.17 0.8058
Entamoeba histolytica tyrosin kinase, putative 0.0303 0.1824 0.3777
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0241 0.0488
Schistosoma mansoni nck2/grb4 0.0463 0.2859 0.2854
Trypanosoma cruzi tubulin delta chain 0.0091 0.045 0.2111
Echinococcus multilocularis tyrosine protein kinase Abl 0.0766 0.4819 0.4816
Loa Loa (eye worm) TK/ROR protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi nuclear receptor RXR 0.0025 0.0023 0.0035
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0766 0.4819 0.4816
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0196 0.0394
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0241 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0358
Giardia lamblia Epsilon tubulin 0.0091 0.045 0.2111
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase domain containing protein 0.0304 0.1831 0.3791
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus granulosus peroxidasin 0.0597 0.3721 0.3717
Echinococcus multilocularis ephrin type A receptor 4 A 0.0303 0.1824 0.1819
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) STAT protein 0.0463 0.2859 0.5927
Onchocerca volvulus 0.0597 0.3721 0.7716
Onchocerca volvulus 0.0463 0.2859 0.5921
Onchocerca volvulus 0.0303 0.1824 0.3768
Echinococcus multilocularis geminin 0.0586 0.3651 0.3647
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0058 0.0241 0.0488
Echinococcus multilocularis tyrosine protein kinase csk 0.0303 0.1824 0.1819
Echinococcus multilocularis beta tubulin 0.0347 0.2105 0.21
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0118 0.033
Loa Loa (eye worm) RGC/RGC protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0013 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0006 0.0022
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0034 0.0028
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0133 0.1691
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0082 0.0157
Brugia malayi hypothetical protein 0.0048 0.0175 0.0351
Echinococcus granulosus intermediate filament protein 0.009 0.0444 0.0437
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0043 0.0142 0.0136
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0617 0.2911
Echinococcus granulosus peroxisome assembly protein 26 0.0284 0.17 0.1695
Trichomonas vaginalis tubulin alpha chain, putative 0.0347 0.2105 0.6174
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0054 0.0214 0.0928
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus signal transduction protein lnk realted 0.0463 0.2859 0.2854
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Echinococcus multilocularis integrin linked protein kinase 0.0303 0.1824 0.1819
Echinococcus granulosus tyrosine protein kinase Src42A 0.0463 0.2859 0.2854
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus integrin linked protein kinase 0.0303 0.1824 0.1819
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0241 0.0488
Schistosoma mansoni tensin 0.0463 0.2859 0.2854
Onchocerca volvulus Chorion peroxidase homolog 0.0597 0.3721 0.7716
Plasmodium vivax tubulin beta chain, putative 0.0347 0.2105 1
Echinococcus granulosus ecdysone induced protein 78C 0.0058 0.0241 0.0235
Loa Loa (eye worm) BEN-1 protein 0.0347 0.2105 0.4361
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Brugia malayi Pax transcription factor protein 2 0.0275 0.1643 0.3402
Entamoeba histolytica tubulin alpha-1 chain 0.0284 0.17 0.352
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0196 0.0394
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0323 0.0317
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0766 0.4819 0.4816
Leishmania major DNA polymerase eta, putative 0.0022 0.0006 0.003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0043 0.0142 0.2825
Loa Loa (eye worm) hypothetical protein 0.0113 0.0592 0.1216
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Trypanosoma brucei epsilon tubulin 0.0209 0.1213 0.5758
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0303 0.1824 0.3777
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0214 0.101
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Mycobacterium ulcerans putative regulatory protein 0.0041 0.013 0.1649
Brugia malayi nuclear receptor NHR-88 0.0025 0.0023 0.0035
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Trichomonas vaginalis tubulin alpha chain, putative 0.0118 0.0627 0.1826
Loa Loa (eye worm) SH2 domain-containing protein 0.0463 0.2859 0.5927
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.0756 1
Brugia malayi hypothetical protein 0.0597 0.3721 0.7719
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0766 0.4819 0.4816
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0142 0.0398
Leishmania major gamma-tubulin 0.0209 0.1213 0.5761
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Giardia lamblia Protein 21.1 0.0303 0.1824 0.866
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Leishmania major protein kinase, putative 0.0303 0.1824 0.8664
Schistosoma mansoni tubulin subunit epsilon 0.0209 0.1213 0.1207
Echinococcus granulosus single minded 2 0.0045 0.0155 0.0149
Onchocerca volvulus 0.0463 0.2859 0.5921
Onchocerca volvulus 0.0055 0.022 0.0432
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Echinococcus granulosus neuropeptide receptor A26 0.0545 0.3387 0.3383
Schistosoma mansoni cell polarity protein 0.0077 0.0362 0.0356
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0766 0.4819 0.4816
Schistosoma mansoni adapter molecule crk 0.0463 0.2859 0.2854
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0323 0.0317
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0117 0.0617 0.2932
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0077 0.0362 0.0739
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0021 0.0191
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0422 0.0863
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0303 0.1824 0.1819
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0079 0.0215
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0323 0.0657
Echinococcus granulosus SH2 motif 0.0463 0.2859 0.2854
Brugia malayi Cytochrome P450 family protein 0.0049 0.0181 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0096 0.0485 0.0479
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.1824 0.1819
Trichomonas vaginalis bromodomain-containing protein, putative 0.0053 0.0204 0.0581
Onchocerca volvulus 0.0069 0.031 0.0619
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis tyrosine kinase 0.0766 0.4819 0.4816
Brugia malayi Tyrosine-protein kinase PR2 0.0303 0.1824 0.3777
Echinococcus granulosus expressed conserved protein 0.0106 0.0548 0.0542
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0157
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Brugia malayi Inositol-1 0.0042 0.0133 0.0263
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Brugia malayi acetyltransferase, GNAT family protein 0.0172 0.0978 0.2019
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0303 0.1824 0.8663
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0284 0.17 0.4983
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0059 0.0246 0.0499
Trypanosoma brucei beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Brugia malayi hypothetical protein 0.0463 0.2859 0.5927
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Echinococcus granulosus tyrosine protein kinase Lyn 0.0767 0.4826 0.4823
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Brugia malayi alpha-tubulin 0.0284 0.17 0.352
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0303 0.1824 0.1819
Echinococcus multilocularis protein patched 0.0048 0.0176 0.017
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0024 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) TK/FAK protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0766 0.4819 0.4816
Brugia malayi C-terminal src kinase protein 1 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0082 0.0075
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0023 0.0017
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0133 0.0263
Plasmodium falciparum alpha tubulin 1 0.0284 0.17 0.8058
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0214 0.0208
Leishmania major beta tubulin 0.0347 0.2105 1
Trichomonas vaginalis set domain proteins, putative 0.0548 0.3406 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Schistosoma mansoni lamin 0.009 0.0444 0.0437
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0236 0.1035
Trichomonas vaginalis tubulin gamma chain, putative 0.0209 0.1213 0.3549
Trypanosoma brucei protein kinase, putative 0.0117 0.0617 0.2926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0196 0.0558
Schistosoma mansoni inositol monophosphatase 0.0042 0.0133 0.0127
Brugia malayi Protein kinase domain containing protein 0.0766 0.4819 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0144 0.0285
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0303 0.1824 0.3777
Schistosoma mansoni hypothetical protein 0.0047 0.0165 0.0159
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0053 0.0204 0.088
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Echinococcus multilocularis SHC transforming protein 3 0.0463 0.2859 0.2854
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0463 0.2859 0.2854
Trypanosoma brucei Flagellum attachment zone protein 20 0.0303 0.1824 0.8663
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0617 0.1797
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0023 0.0017
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0082 0.0157
Onchocerca volvulus Putative cubilin 0.0077 0.0362 0.0727
Onchocerca volvulus 0.0157 0.0878 0.1801
Echinococcus multilocularis kinase suppressor of Ras 1 0.0303 0.1824 0.1819
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0196 0.019
Brugia malayi photoreceptor-specific nuclear receptor 0.0058 0.0241 0.0488
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0303 0.1824 0.5346
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0463 0.2859 0.5927
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0463 0.2859 0.2854
Echinococcus granulosus retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Brugia malayi Tubulin alpha-2 chain 0.0284 0.17 0.352
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0042 0.0133 0.0263
Echinococcus multilocularis SH2 motif 0.0463 0.2859 0.2854
Plasmodium falciparum tubulin delta chain, putative 0.0091 0.045 0.2057
Echinococcus multilocularis musashi 0.009 0.0444 0.0437
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0463 0.2859 0.5927
Echinococcus granulosus tyrosine protein kinase Blk 0.0766 0.4819 0.4816
Leishmania major beta tubulin 0.0347 0.2105 1
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0142 0.0398
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0176 0.017
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0058 0.0241 0.0475
Giardia lamblia Beta tubulin 0.0347 0.2105 1
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0481 0.2976 0.617
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Schistosoma mansoni zinc finger protein 0.0025 0.0023 0.0017
Echinococcus granulosus protein tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Echinococcus multilocularis neurogenic locus notch protein 0.0077 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0054 0.0213 0.0429
Echinococcus granulosus survival motor neuron protein 1 0.027 0.1612 0.1607
Trypanosoma brucei beta tubulin 0.0209 0.1213 0.5758
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0108
Loa Loa (eye worm) tubulin gamma chain 0.0209 0.1213 0.2507
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Protein kinase domain containing protein 0.0766 0.4819 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0196 0.0558
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0133 0.0127
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0162 0.0155
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0023 0.0017
Echinococcus granulosus tubulin alpha 3 chain 0.0284 0.17 0.1695
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0193 0.1115 0.2303
Leishmania major protein kinase, putative 0.0304 0.1831 0.8696
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0023 0.0017
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Echinococcus multilocularis slit 2 protein 0.0077 0.0362 0.0356
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi SH2 domain containing protein 0.0766 0.4819 1
Schistosoma mansoni growth factor receptor-bound protein 0.0463 0.2859 0.2854
Schistosoma mansoni hypothetical protein 0.0078 0.0368 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi hypothetical protein 0.0034 0.0082 0.0157
Leishmania major beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) tubulin alpha-2 chain 0.0284 0.17 0.352
Brugia malayi RhoGAP domain containing protein 0.0463 0.2859 0.5927
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) BEN-1 protein 0.0347 0.2105 0.4361
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0463 0.2859 0.5921
Loa Loa (eye worm) TK/EGFR protein kinase 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi cytoplasmic intermediate filament protein 0.0048 0.0174 0.0349
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0023 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi Tubulin gamma chain 0.0209 0.1213 0.2507
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) Notch2 0.0077 0.0362 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Trichomonas vaginalis STE family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Trichomonas vaginalis tubulin, putative 0.0118 0.0627 0.1826
Schistosoma mansoni steroid hormone receptor ad4bp 0.0058 0.0241 0.0235
Echinococcus multilocularis thyroid hormone receptor alpha 0.0058 0.0241 0.0235
Echinococcus granulosus protein jagged 1 0.0077 0.0362 0.0356
Leishmania major beta tubulin 0.0347 0.2105 1
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Onchocerca volvulus 0.0597 0.3721 0.7716
Loa Loa (eye worm) hypothetical protein 0.0089 0.0439 0.0899
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus multilocularis raf serine:threonine protein kinase 0.0303 0.1824 0.1819
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0026 0.0031 0.0025
Brugia malayi conserved hypotetical protein 0.0025 0.0023 0.0035
Echinococcus granulosus tensin 0.0463 0.2859 0.2854
Brugia malayi Tensin 0.0463 0.2859 0.5927
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0058 0.0241 0.0235
Echinococcus multilocularis tyrosine protein kinase Blk 0.0766 0.4819 0.4816
Echinococcus multilocularis zinc finger protein 0.0027 0.0039 0.0032
Giardia lamblia Kinase, NEK 0.0303 0.1824 0.866
Brugia malayi Animal haem peroxidase family protein 0.0597 0.3721 0.7719
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Onchocerca volvulus Neurogenic locus notch homolog 0.0077 0.0362 0.0727
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni hypothetical protein 0.0047 0.0165 0.0159
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0342 0.0336
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0303 0.1824 0.1819
Brugia malayi Animal haem peroxidase family protein 0.0597 0.3721 0.7719
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0021 0.0098
Echinococcus granulosus retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0043 0.0142 0.0645
Brugia malayi hypothetical protein 0.0075 0.0351 0.0717
Brugia malayi Tubulin beta chain 0.0091 0.045 0.0921
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Echinococcus multilocularis neural cadherin 0.0077 0.0362 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni protein kinase 0.0304 0.1831 0.1826
Echinococcus granulosus tyrosine protein kinase Srms 0.0766 0.4819 0.4816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0107
Loa Loa (eye worm) hypothetical protein 0.0048 0.0175 0.0351
Entamoeba histolytica hypothetical protein 0.012 0.0637 0.1311
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Toxoplasma gondii alpha tubulin TUBA1 0.0284 0.17 0.8058
Loa Loa (eye worm) protein kinase domain-containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) MH2 domain-containing protein 0.026 0.1548 0.3203
Brugia malayi Tubulin beta-1 chain 0.0347 0.2105 0.4361
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus protein jagged 2 0.0077 0.0362 0.0356
Brugia malayi Steroid receptor seven-up type 2 0.0058 0.0241 0.0488
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0062 0.0164
Trichomonas vaginalis tubulin gamma chain, putative 0.0091 0.045 0.1303
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.012 0.0637 0.0631
Schistosoma mansoni tubulin subunit beta 0.0347 0.2105 0.21
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0023 0.0035
Echinococcus granulosus Tubulin beta 2C chain 0.0347 0.2105 0.21
Loa Loa (eye worm) alpha-tubulin 0.0284 0.17 0.352
Onchocerca volvulus 0.0303 0.1824 0.3768
Onchocerca volvulus 0.0118 0.0627 0.1278
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0069 0.0309 0.0629
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0058 0.0241 0.0488
Schistosoma mansoni hypothetical protein 0.0463 0.2859 0.2854
Echinococcus granulosus receptor type guanylyl cyclase 0.0303 0.1824 0.1819
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0304 0.1831 0.1826
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0108
Echinococcus multilocularis protein dispatched 1 0.0055 0.022 0.0214
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0303 0.1824 0.5346
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0069 0.031 0.0304
Echinococcus multilocularis protein jagged 1 0.0077 0.0362 0.0356
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.0592 0.1216
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0422 0.0416
Echinococcus granulosus fibropellin Ia 0.0077 0.0362 0.0356
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Tubulin alpha chain 0.0284 0.17 0.352
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0241 0.0235
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Entamoeba histolytica tubulin family protein 0.0347 0.2105 0.4361
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi Protein kinase domain containing protein 0.0766 0.4819 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Brugia malayi Pre-SET motif family protein 0.0481 0.2976 0.617
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0142 0.0581
Onchocerca volvulus Protein ultraspiracle homolog 0.0058 0.0241 0.0475
Entamoeba histolytica tyrosin kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis notch 0.0077 0.0362 0.0356
Toxoplasma gondii protein kinase 0.0303 0.1824 0.865
Echinococcus multilocularis SH2 domain containing protein 7 0.0463 0.2859 0.2854
Echinococcus granulosus tubulin alpha 0.0209 0.1213 0.1207
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0058 0.0241 0.0235
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0766 0.4819 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0303 0.1824 0.3768
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0006 0.0022
Echinococcus granulosus c src tyrosine kinase 0.0766 0.4819 0.4816
Echinococcus granulosus histone acetyltransferase KAT2B 0.0165 0.0929 0.0924
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0181 0.0362
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Schistosoma mansoni GTPase activating protein 0.0463 0.2859 0.2854
Loa Loa (eye worm) SRC-1 0.0766 0.4819 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0043 0.0142 0.0281
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Loa Loa (eye worm) serine/threonine protein kinase 0.0303 0.1824 0.3777
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0111 0.0433
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0303 0.1824 0.1819
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0463 0.2859 0.2854
Loa Loa (eye worm) SH2 domain-containing protein 0.0463 0.2859 0.5927
Echinococcus multilocularis neurogenic locus notch protein 0.0077 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0095
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0347 0.2105 0.21
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0162 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.045 0.1303
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0133 0.0373
Echinococcus multilocularis Tubulin alpha 1 chain 0.0284 0.17 0.1695
Brugia malayi bone morphogenetic protein type 1 receptor 0.0303 0.1824 0.3777
Toxoplasma gondii alpha-tubulin I, putative 0.0284 0.17 0.8058
Brugia malayi jmjC domain containing protein 0.0069 0.0308 0.0627
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Echinococcus granulosus neurogenic locus protein delta 0.0077 0.0362 0.0356
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0142 0.0581
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Toxoplasma gondii aldehyde dehydrogenase 0.0138 0.0756 0.3525
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0043 0.0144 0.0137
Trypanosoma cruzi alpha tubulin, putative 0.0284 0.17 0.8071
Schistosoma mansoni nuclear receptor 0.0025 0.0023 0.0017
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0105 0.1314
Leishmania major DNA polymerase kappa, putative 0.0022 0.0006 0.003
Echinococcus granulosus tubulin epsilon chain 0.0209 0.1213 0.1207
Echinococcus multilocularis isocitrate dehydrogenase 0.0054 0.0214 0.0208
Leishmania major beta tubulin 0.0347 0.2105 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0058 0.0241 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0077 0.0362 0.0356
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0463 0.2859 0.2854
Onchocerca volvulus 0.0041 0.013 0.0244
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0463 0.2859 0.5927
Brugia malayi SH2 domain containing protein 0.0463 0.2859 0.5927
Schistosoma mansoni transcription factor LCR-F1 0.012 0.0637 0.0631
Loa Loa (eye worm) hypoxia-induced factor 1 0.0172 0.0977 0.2017
Echinococcus multilocularis jun protein 0.0096 0.0485 0.0479
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0181 0.083
Loa Loa (eye worm) inositol-1 0.0042 0.0133 0.0263
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) blistered cuticle protein 3 0.0597 0.3721 0.7719
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0136 0.013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0241 0.0488
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Plasmodium falciparum protein kinase, putative 0.0303 0.1824 0.865
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0463 0.2859 0.2854
Schistosoma mansoni tensin 0.0463 0.2859 0.2854
Onchocerca volvulus 0.0303 0.1824 0.3768
Loa Loa (eye worm) hypothetical protein 0.0187 0.1071 0.2211
Echinococcus multilocularis tyrosine protein kinase csk 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0043 0.0142 0.0281
Echinococcus granulosus SHC transforming protein 3 0.0463 0.2859 0.2854
Echinococcus multilocularis tubulin alpha chain 0.0284 0.17 0.1695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0196 0.0558
Onchocerca volvulus 0.0766 0.4819 1
Plasmodium vivax tubulin epsilon chain, putative 0.0209 0.1213 0.5719
Schistosoma mansoni jun-related protein 0.0078 0.0368 0.0362
Loa Loa (eye worm) RGC/RGC protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Echinococcus multilocularis caspase 2 0.0069 0.0309 0.0303
Schistosoma mansoni patched 1 0.0048 0.0176 0.017
Loa Loa (eye worm) tubulin alpha 2 0.0193 0.1115 0.2303
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0088 0.043 0.0881
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Echinococcus multilocularis natriuretic peptide receptor 1 0.0303 0.1824 0.1819
Onchocerca volvulus 0.0766 0.4819 1
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0209 0.1213 0.5719
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0463 0.2859 0.2854
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0021 0.0191
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Echinococcus granulosus mitogen activated protein kinase 3 0.0117 0.0617 0.0611
Trypanosoma brucei tubulin delta chain 0.0091 0.045 0.2129
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0439 0.0433
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0303 0.1824 0.1819
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0463 0.2859 0.5921
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0303 0.1824 0.1819
Entamoeba histolytica ankyrin repeat protein 0.0303 0.1824 0.3777
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Trypanosoma brucei unspecified product 0.0022 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0181 0.083
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0058 0.0241 0.0488
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus SH2 motif 0.0463 0.2859 0.2854
Brugia malayi MH2 domain containing protein 0.026 0.1548 0.3203
Brugia malayi Cytochrome P450 family protein 0.0063 0.0274 0.0557
Echinococcus multilocularis lamin dm0 0.009 0.0444 0.0437
Brugia malayi Bromodomain containing protein 0.0092 0.0458 0.0937
Brugia malayi Bromodomain containing protein 0.0049 0.018 0.0361
Trichomonas vaginalis tubulin, putative 0.0347 0.2105 0.6174
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0927 0.586 0.5858
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0303 0.1824 0.1819
Trypanosoma cruzi zeta tubulin, putative 0.0091 0.045 0.2111
Loa Loa (eye worm) hypothetical protein 0.0157 0.0878 0.1811
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Leishmania major beta tubulin 0.0347 0.2105 1
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.17 0.4983
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Echinococcus multilocularis neurogenic locus protein delta 0.0077 0.0362 0.0356
Echinococcus multilocularis ecdysone induced protein 78C 0.0058 0.0241 0.0235
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi PAS domain containing protein 0.0056 0.0223 0.0451
Trypanosoma brucei protein kinase, putative 0.0304 0.1831 0.8695
Echinococcus granulosus tubulin delta chain 0.0091 0.045 0.0443
Echinococcus granulosus tyrosine kinase 0.0766 0.4819 0.4816
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0077 0.0362 0.0727
Echinococcus granulosus Tubulin beta 2C chain 0.0347 0.2105 0.21
Echinococcus multilocularis SH2 motif 0.0463 0.2859 0.2854
Echinococcus granulosus Niemann Pick C1 protein 0.0161 0.0904 0.0898
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0196 0.019
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0013 0.0085
Loa Loa (eye worm) tubulin beta chain 0.0091 0.045 0.0921
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0058 0.0241 0.0488
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0117 0.0617 0.2911
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0058 0.0241 0.0235
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0013 0.0013
Echinococcus multilocularis tubulin delta chain 0.0091 0.045 0.0443
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Plasmodium vivax tyrosine kinase-like protein, putative 0.0303 0.1824 0.865
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0138 0.0756 0.075
Toxoplasma gondii beta tubulin 0.0347 0.2105 1
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Echinococcus granulosus tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0058 0.0241 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0058 0.0241 0.0488
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.012 0.0637 0.0631
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0023 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0058 0.0241 0.0235
Echinococcus granulosus delta-like protein 1 0.0077 0.0362 0.0356
Brugia malayi hypothetical protein 0.0187 0.1071 0.2211
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0138 0.0756 0.075
Echinococcus multilocularis c src tyrosine kinase 0.0766 0.4819 0.4816
Schistosoma mansoni tensin-related 0.0463 0.2859 0.2854
Schistosoma mansoni alpha tubulin 0.0284 0.17 0.1695
Trichomonas vaginalis tubulin gamma chain, putative 0.0209 0.1213 0.3549
Brugia malayi Protein kinase domain containing protein 0.0766 0.4819 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0284 0.17 0.4983
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0766 0.4819 0.4816
Schistosoma mansoni retinoic acid receptor RXR 0.0058 0.0241 0.0235
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.004 0.0121 0.0239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0043 0.0142 0.0645
Echinococcus multilocularis hypothetical protein 0.0284 0.17 0.1695
Loa Loa (eye worm) tubulin beta-1 chain 0.0347 0.2105 0.4361
Trypanosoma brucei beta tubulin 0.0347 0.2105 1
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0023 0.0017
Echinococcus multilocularis Tubulin beta 2C chain 0.0347 0.2105 0.21
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0034 0.0028
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0058 0.0241 0.0235
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0303 0.1824 0.1819
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0107
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0133 0.0539
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0023 0.0035
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0054 0.0214 0.099
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Brugia malayi bHLH-PAS transcription factor 0.0041 0.013 0.0257
Chlamydia trachomatis endonuclease IV 0.0088 0.043 1
Trichomonas vaginalis tubulin beta chain, putative 0.0347 0.2105 0.6174
Brugia malayi tubulin alpha-2 chain 0.0284 0.17 0.352
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Schistosoma mansoni serine/threonine RGC 0.0303 0.1824 0.1819
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.009 0.0444 0.0908
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica tyrosin kinase, putative 0.0303 0.1824 0.3777
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0117 0.0617 0.2932
Echinococcus multilocularis tumor protein p63 0.0386 0.2362 0.2358
Brugia malayi ecdysteroid receptor 0.0058 0.0241 0.0488
Trichomonas vaginalis tubulin alpha chain, putative 0.0118 0.0627 0.1826
Echinococcus granulosus tyrosine protein kinase shark 0.0766 0.4819 0.4816
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0308 0.0302
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0304 0.1831 0.1826
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0023 0.0035
Echinococcus multilocularis tyrosine protein kinase Srms 0.0766 0.4819 0.4816
Echinococcus granulosus activated cdc42 kinase 1 0.0303 0.1824 0.1819
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0463 0.2859 0.2854
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0108
Loa Loa (eye worm) TK/Met protein kinase 0.0303 0.1824 0.3777
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0196 0.0931
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0176 0.0353
Brugia malayi Cadherin domain containing protein 0.0077 0.0362 0.0739
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0308 0.0302
Mycobacterium ulcerans epimerase 0.0023 0.0013 0.0085
Onchocerca volvulus 0.0077 0.0362 0.0727
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0303 0.1824 0.3777
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0133 0.2621
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Brugia malayi Animal haem peroxidase family protein 0.0597 0.3721 0.7719
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0135 0.0129
Giardia lamblia Alpha-tubulin 0.0284 0.17 0.8071
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0058 0.0241 0.0235
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Schistosoma mansoni SH2A 0.0463 0.2859 0.2854
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0464 0.2866 0.5941
Echinococcus multilocularis insulin receptor 0.0303 0.1824 0.1819
Schistosoma mansoni single-minded 0.0056 0.0223 0.0217
Echinococcus multilocularis tyrosine protein kinase 0.0303 0.1824 0.1819
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0058 0.0241 0.0488
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0058 0.0241 0.0488
Trichomonas vaginalis tubulin alpha chain, putative 0.0118 0.0627 0.1826
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0058 0.0241 0.0235
Onchocerca volvulus 0.0275 0.1643 0.3393
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus multilocularis FL cytokine receptor 0.0303 0.1824 0.1819
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0439 0.0433
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0023 0.0035
Brugia malayi Animal haem peroxidase family protein 0.0597 0.3721 0.7719
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica tubulin family protein 0.0347 0.2105 0.4361
Brugia malayi cytokine inducible SH2-containing protein 5 0.0463 0.2859 0.5927
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0138 0.0756 0.3589
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Echinococcus multilocularis protein jagged 2 0.0077 0.0362 0.0356
Trichomonas vaginalis tubulin alpha chain, putative 0.0209 0.1213 0.3549
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.0592 0.0586
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0026 0.0031 0.0025
Schistosoma mansoni caspase-7 (C14 family) 0.0069 0.0309 0.0303
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Brugia malayi Cell division protein ftsZ 0.0091 0.045 0.0921
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Echinococcus granulosus tyrosine protein kinase csk 0.0303 0.1824 0.1819
Trichomonas vaginalis TK family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) SH2 domain-containing protein 0.0463 0.2859 0.5927
Echinococcus multilocularis 0.0463 0.2859 0.2854
Loa Loa (eye worm) hypothetical protein 0.0284 0.17 0.352
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) TK/RYK protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Toxoplasma gondii beta-tubulin, putative 0.0347 0.2105 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0303 0.1824 0.1819
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0023 0.0017
Toxoplasma gondii beta-1 tubulin, putative 0.0347 0.2105 1
Giardia lamblia High cysteine protein 0.0077 0.0362 0.1695
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.022 0.0445
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0023 0.0017
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0128 0.0602
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Brugia malayi nuclear receptor RXR 0.0034 0.0082 0.0157
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0241 0.0235
Echinococcus granulosus tyrosine protein kinase csk 0.0303 0.1824 0.1819
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Trypanosoma cruzi protein kinase, putative 0.0303 0.1824 0.866
Echinococcus multilocularis N chimaerin 0.0463 0.2859 0.2854
Onchocerca volvulus 0.0766 0.4819 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0193 0.1115 0.326
Echinococcus multilocularis tyrosine protein kinase csk 0.0303 0.1824 0.1819
Echinococcus granulosus apoptotic protease activating factor 1 0.0048 0.0175 0.0169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0058 0.0241 0.0488
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Trypanosoma brucei alpha tubulin 0.0284 0.17 0.8075
Loa Loa (eye worm) animal heme peroxidase 0.0597 0.3721 0.7719
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0058 0.0241 0.0488
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0617 0.1797
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0241 0.0488
Mycobacterium ulcerans aldehyde dehydrogenase 0.0138 0.0756 1
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) notch protein 0.0077 0.0362 0.0739
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0766 0.4819 0.4816
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0303 0.1824 0.1819
Onchocerca volvulus 0.009 0.0444 0.0896
Entamoeba histolytica SH2 domain containing protein 0.0463 0.2859 0.5927
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Schistosoma mansoni hypothetical protein 0.0586 0.3651 0.3647
Echinococcus granulosus tyrosine protein kinase Src64B 0.0766 0.4819 0.4816
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Echinococcus multilocularis tyrosine protein kinase shark 0.0766 0.4819 0.4816
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0323 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Onchocerca volvulus Peroxidase homolog 0.0597 0.3721 0.7716
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0274 0.0557
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0304 0.1831 0.8695
Echinococcus granulosus natriuretic peptide receptor 1 0.0303 0.1824 0.1819
Echinococcus granulosus tubulin alpha chain 0.0284 0.17 0.1695
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0133 0.0127
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0043 0.0144 0.0137
Brugia malayi Blistered cuticle protein 3 0.0597 0.3721 0.7719
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.1824 0.5346
Echinococcus multilocularis tensin 0.0463 0.2859 0.2854
Mycobacterium tuberculosis Cell division protein FtsZ 0.0091 0.045 0.5915
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0196 0.0924
Brugia malayi nuclear receptor NHR-67 0.0025 0.0023 0.0035
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus multilocularis tubulin alpha 0.0209 0.1213 0.1207
Leishmania major beta tubulin 0.0347 0.2105 1
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi Sex muscle abnormal protein 5 0.0463 0.2859 0.5927
Toxoplasma gondii LsmAD domain-containing protein 0.0058 0.0236 0.1035
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0006 0.0022
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus tubulin alpha chain 0.0284 0.17 0.1695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0128 0.0358
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Echinococcus multilocularis mitogen activated protein kinase 0.0117 0.0617 0.0611
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Schistosoma mansoni suppressor of cytokine signaling 0.0463 0.2859 0.2854
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Loa Loa (eye worm) TK/ACK protein kinase 0.0303 0.1824 0.3777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0111 0.0307
Schistosoma mansoni protein kinase 0.0304 0.1831 0.1826
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0597 0.3721 0.7719
Onchocerca volvulus 0.0057 0.0229 0.0451
Echinococcus granulosus neurogenic locus notch protein 4 0.0077 0.0362 0.0356
Onchocerca volvulus 0.0766 0.4819 1
Echinococcus granulosus notch 0.0077 0.0362 0.0356
Loa Loa (eye worm) tubulin alpha 2 0.0075 0.0351 0.0716
Echinococcus granulosus tyrosine protein kinase csk 0.0303 0.1824 0.1819
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0058 0.0241 0.0235
Brugia malayi PHD-finger family protein 0.0033 0.0079 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) steroid hormone receptor 0.0058 0.0241 0.0488
Entamoeba histolytica hypothetical protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) tubulin beta-4 chain 0.0347 0.2105 0.4361
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Leishmania major alpha tubulin 0.0284 0.17 0.8077
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0058 0.0241 0.0488
Schistosoma mansoni hypothetical protein 0.0077 0.0362 0.0356
Echinococcus granulosus tubulin subunit beta 0.0347 0.2105 0.21
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0117 0.0617 0.2926
Echinococcus multilocularis apoptotic protease activating factor 1 0.0048 0.0175 0.0169
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0023 0.0035
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Onchocerca volvulus 0.0058 0.0241 0.0475
Schistosoma mansoni ephrin receptor 0.0303 0.1824 0.1819
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0303 0.1824 0.3777
Brugia malayi bZIP transcription factor family protein 0.0096 0.0485 0.0994
Loa Loa (eye worm) TK/DDR protein kinase 0.0303 0.1824 0.3777
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0196 0.0394
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Loa Loa (eye worm) TK/FER protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0739
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0241 0.0235
Loa Loa (eye worm) hypothetical protein 0.0193 0.1115 0.2303
Loa Loa (eye worm) hypothetical protein 0.0058 0.0241 0.0488
Brugia malayi exodeoxyribonuclease III family protein 0.0043 0.0142 0.0281
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Brugia malayi isocitrate dehydrogenase 0.0054 0.0214 0.0432
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0054 0.0214 0.101
Brugia malayi Tyrosine-protein kinase abl-1 0.0766 0.4819 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.0463 0.2859 0.2854
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0133 0.0632
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Schistosoma mansoni tubulin subunit alpha 0.0284 0.17 0.1695
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0241 0.0487
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Entamoeba histolytica hypothetical protein 0.0024 0.0021 0.003
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0303 0.1824 0.3777
Echinococcus granulosus tubulin alpha 3 chain 0.0284 0.17 0.1695
Trypanosoma brucei alpha tubulin 0.0284 0.17 0.8075
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0053 0.0204 0.0581
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Echinococcus granulosus FTZ F1 alpha 0.0058 0.0241 0.0235
Loa Loa (eye worm) TK protein kinase 0.0766 0.4819 1
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Schistosoma mansoni protein kinase 0.0303 0.1824 0.1819
Schistosoma mansoni aldehyde dehydrogenase 0.0138 0.0756 0.075
Echinococcus granulosus retinal guanylyl cyclase 2 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0057 0.0229 0.0463
Loa Loa (eye worm) RGC/RGC protein kinase 0.0303 0.1824 0.3777
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0241 0.0235
Loa Loa (eye worm) tubulin alpha chain 0.0284 0.17 0.352
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0617 0.0611
Echinococcus multilocularis peroxidasin 0.0597 0.3721 0.3717
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0118 0.033
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0303 0.1824 0.3777
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0117 0.0617 0.2911
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Brugia malayi hypothetical protein 0.0025 0.0023 0.0035
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0157
Echinococcus granulosus beta tubulin 0.0347 0.2105 0.21
Onchocerca volvulus Peroxidasin homolog 0.0597 0.3721 0.7716
Brugia malayi GCC2 and GCC3 family protein 0.0077 0.0362 0.0739
Brugia malayi Cadherin domain containing protein 0.0077 0.0362 0.0739
Echinococcus granulosus hypothetical protein 0.0463 0.2859 0.2854
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Schistosoma mansoni microtubule-associated protein tau 0.1567 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Echinococcus granulosus geminin 0.0586 0.3651 0.3647
Schistosoma mansoni alpha tubulin 0.0284 0.17 0.1695
Echinococcus granulosus neuropeptide s receptor 0.0545 0.3387 0.3383
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0617 0.1797
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0128 0.0581
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0023 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0023 0.0017
Plasmodium falciparum protein kinase, putative 0.0303 0.1824 0.865
Entamoeba histolytica serine/threonine kinase, putative 0.0303 0.1824 0.3777
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0136 0.013
Loa Loa (eye worm) hypothetical protein 0.0088 0.0433 0.0886
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0196 0.0394
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0422 0.0416
Brugia malayi hypothetical protein 0.0303 0.1824 0.3777
Echinococcus multilocularis fat cadherin tumor suppressor 0.0077 0.0362 0.0356
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Brugia malayi Variant SH3 domain containing protein 0.0463 0.2859 0.5927
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0617 0.1797
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0303 0.1824 0.1819
Loa Loa (eye worm) TK/FER protein kinase 0.0766 0.4819 1
Echinococcus multilocularis tubulin epsilon chain 0.0209 0.1213 0.1207
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0342 0.0336
Echinococcus granulosus lamin dm0 0.009 0.0444 0.0437
Brugia malayi Variant SH3 domain containing protein 0.0463 0.2859 0.5927
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0176 0.017
Trypanosoma brucei beta tubulin 0.0347 0.2105 1
Brugia malayi Raf kinase 0.0303 0.1824 0.3777
Brugia malayi Variant SH3 domain containing protein 0.0463 0.2859 0.5927
Brugia malayi notch-like transmembrane receptor 0.0077 0.0362 0.0739
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0043 0.0142 0.0136
Echinococcus multilocularis survival motor neuron protein 1 0.027 0.1612 0.1607
Brugia malayi SRC-1 0.0766 0.4819 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0766 0.4819 0.4816
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0176 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Giardia lamblia Kinase, NEK 0.0303 0.1824 0.866
Brugia malayi Protein kinase domain containing protein 0.0303 0.1824 0.3777
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0105 0.2108
Onchocerca volvulus 0.0077 0.0362 0.0727
Schistosoma mansoni ap endonuclease 0.0043 0.0142 0.0136
Onchocerca volvulus 0.0303 0.1824 0.3768
Schistosoma mansoni tyrosine kinase 0.0766 0.4819 0.4816
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0058 0.0241 0.0235
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0159 0.0318
Schistosoma mansoni hypothetical protein 0.0463 0.2859 0.2854
Mycobacterium ulcerans hypothetical protein 0.0023 0.0013 0.0085
Brugia malayi Guanylyl cyclase protein 23 0.0303 0.1824 0.3777
Plasmodium vivax SET domain protein, putative 0.0069 0.031 0.1388
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0166 0.0937 0.2737
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0303 0.1824 0.3777
Schistosoma mansoni inositol monophosphatase 0.0042 0.0133 0.0127
Brugia malayi SH2 domain containing protein 0.0766 0.4819 1
Schistosoma mansoni tensin 0.0463 0.2859 0.2854
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0303 0.1824 0.1819
Trypanosoma brucei tubulin gamma chain 0.0209 0.1213 0.5758
Loa Loa (eye worm) hypothetical protein 0.0048 0.0176 0.0353
Echinococcus granulosus SH2 domain containing adapter protein F 0.0463 0.2859 0.2854
Brugia malayi Calcium binding EGF domain containing protein 0.0077 0.0362 0.0739
Schistosoma mansoni tyrosine kinase 0.0303 0.1824 0.1819
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.043 0.1966
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.045 0.1303
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Loa Loa (eye worm) TK/CSK protein kinase 0.0303 0.1824 0.3777
Onchocerca volvulus 0.0025 0.0023 0.0022
Loa Loa (eye worm) acetyltransferase 0.0172 0.0978 0.2019
Entamoeba histolytica tyrosine kinase, putative 0.0303 0.1824 0.3777
Echinococcus granulosus tubulin alpha 1C chain 0.0284 0.17 0.1695
Brugia malayi Receptor family ligand binding region containing protein 0.0303 0.1824 0.3777
Trichomonas vaginalis CAMK family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0157
Loa Loa (eye worm) TK protein kinase 0.0303 0.1824 0.3777
Loa Loa (eye worm) hypothetical protein 0.0463 0.2859 0.5927
Leishmania major delta tubulin, putative 0.0091 0.045 0.2135
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.013 0.0124
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0023 0.0017
Echinococcus granulosus protein jagged 2 0.0077 0.0362 0.0356
Echinococcus granulosus Tubulin beta 2C chain 0.0347 0.2105 0.21
Onchocerca volvulus Dual oxidase homolog 0.0597 0.3721 0.7716
Schistosoma mansoni notch 0.0077 0.0362 0.0356
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0058 0.0241 0.0235
Brugia malayi EGF-like domain containing protein 0.0077 0.0362 0.0739
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0303 0.1824 0.3777
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0058 0.0236 0.0478
Trichomonas vaginalis TKL family protein kinase 0.0303 0.1824 0.5346
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Echinococcus granulosus epidermal growth factor receptor 0.0303 0.1824 0.1819
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0035
Brugia malayi hypothetical protein 0.0058 0.0236 0.0478
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0303 0.1824 0.3777
Echinococcus granulosus neural cadherin 0.0077 0.0362 0.0356
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0196 0.0903
Echinococcus multilocularis tyrosine protein kinase pr2 0.0303 0.1824 0.1819
Entamoeba histolytica protein kinase, putative 0.0303 0.1824 0.3777
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0136 0.027
Schistosoma mansoni signal transduction protein lnk-related 0.0463 0.2859 0.2854
Echinococcus multilocularis tubulin alpha 1C chain 0.0284 0.17 0.1695
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0241 0.0488
Onchocerca volvulus 0.0463 0.2859 0.5921
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.031 0.1388
Onchocerca volvulus 0.0303 0.1824 0.3768
Echinococcus granulosus Tubulin alpha 1 chain 0.0284 0.17 0.1695
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0214 0.099
Toxoplasma gondii EGF family domain-containing protein 0.0077 0.0362 0.1638

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 0.398 Agonist activity human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase relative to NECA ChEMBL. 18321038
Activity (functional) = 0.398 Agonist activity human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase relative to NECA ChEMBL. 18321038
EC50 (binding) = 0.96 uM Receptor-stimulated activity in CHO cells stably transfected with Human recombinant Adenosine A2B receptor using [3H]-NECA as radioligand ChEMBL. 12109910
Ki (binding) = 1.5 nM Binding affinity against Human recombinant Adenosine A3 receptor stably transfected in CHO cells using [3H]-NECA as radioligand ChEMBL. 12109910
Ki (binding) = 1.7 nM Binding affinity against Human recombinant Adenosine A1 receptor stably transfected in CHO cells using [3H]-CCPA as radioligand ChEMBL. 12109910
Ki (binding) = 43 nM Binding affinity against Human recombinant Adenosine A2A receptor stably transfected in CHO cells using [3H]-NECA as radioligand ChEMBL. 12109910
logEC50 (functional) = -2.982 Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase ChEMBL. 18321038
logEC50 (functional) = -2.982 Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase ChEMBL. 18321038

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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