Detailed information for compound 899509

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.432 | Formula: C17H21N3O3S
  • H donors: 1 H acceptors: 3 LogP: 1.62 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN=C1SC(C(=O)N1CC)CC(=O)Nc1ccc(cc1)C(=O)C
  • InChi: 1S/C17H21N3O3S/c1-4-18-17-20(5-2)16(23)14(24-17)10-15(22)19-13-8-6-12(7-9-13)11(3)21/h6-9,14H,4-5,10H2,1-3H3,(H,19,22)/b18-17-
  • InChiKey: XAAPWLPKAVIJAU-ZCXUNETKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni bromodomain containing protein 0.0068 0.0157 0.0268
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0368 0.0626
Echinococcus granulosus tar DNA binding protein 0.0241 0.0667 0.0667
Echinococcus granulosus beta LACTamase domain containing family member 0.0025 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Brugia malayi Cathepsin L-like cysteine proteinase 0.0282 0.0789 0.1344
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0073 0.0073
Loa Loa (eye worm) sfrp2 0.007 0.0166 0.0169
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0202 0.0344
Echinococcus multilocularis muscleblind protein 0.0305 0.0857 0.0857
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0023 0.0025 0.0161
Schistosoma mansoni frizzled-like receptor 0.0083 0.0203 0.0346
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0202 0.0344
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0312 0.0531
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0028 0.0029
Leishmania major hypothetical protein, conserved 0.0025 0.0031 0.0154
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Echinococcus multilocularis zinc finger protein 0.0023 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0026 0.0045
Echinococcus granulosus cathepsin L 0.023 0.0637 0.0637
Entamoeba histolytica cysteine proteinase 1, putative 0.023 0.0637 0.5719
Onchocerca volvulus 0.0713 0.2058 0.9196
Brugia malayi mbt repeat family protein 0.0086 0.0213 0.0362
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0073 0.0125
Loa Loa (eye worm) beta-lactamase 0.0025 0.0031 0.0032
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.0816 0.4012
Echinococcus granulosus secreted frizzled protein 0.007 0.0166 0.0166
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Brugia malayi MH2 domain containing protein 0.0024 0.0028 0.0048
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Loa Loa (eye worm) isocitrate dehydrogenase 0.0023 0.0025 0.0025
Schistosoma mansoni frizzled-like receptor 0.0154 0.0411 0.0699
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0202 0.0344
Plasmodium falciparum cysteine proteinase falcipain 3 0.0392 0.1115 1
Brugia malayi nuclear hormone receptor 0.0083 0.0202 0.0344
Echinococcus multilocularis dna polymerase eta 0.0033 0.0055 0.0055
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0036 0.0037
Loa Loa (eye worm) transcription factor SMAD2 0.0348 0.0983 0.1004
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0229 0.0389
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) RNA binding protein 0.0241 0.0667 0.0682
Echinococcus multilocularis jumonji domain containing protein 0.003 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0621 0.1787 0.3041
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.042
Schistosoma mansoni smad 0.0024 0.0028 0.0048
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0226 0.0226
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0018 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Loa Loa (eye worm) hypothetical protein 0.0474 0.1355 0.1384
Plasmodium vivax vivapain-2 0.0392 0.1115 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0823 0.1401
Loa Loa (eye worm) TAR-binding protein 0.0241 0.0667 0.0682
Schistosoma mansoni sex comb on midleg homolog 0.0086 0.0213 0.0362
Leishmania major T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0037
Brugia malayi nuclear receptor NHR-88 0.0039 0.0073 0.0125
Echinococcus granulosus lamin 0.002 0.0018 0.0018
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.007 0.0163 0.0167
Trypanosoma cruzi cruzipain precursor, putative 0.0392 0.1115 0.1897
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Plasmodium falciparum serine repeat antigen 6 0.012 0.0312 0.2753
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0377 0.9109
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Brugia malayi Heterochromatin protein 1 0.0051 0.0109 0.0185
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Echinococcus multilocularis cathepsin L cysteine protease 0.0392 0.1115 0.1115
Brugia malayi ecdysone receptor 0.0039 0.0073 0.0125
Onchocerca volvulus 0.0083 0.0202 0.0897
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0043 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0031 0.0154
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0023 0.0025 0.0025
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0202 0.0202
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Echinococcus multilocularis snurportin 1 0.0454 0.1297 0.1297
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Trypanosoma cruzi ISWI complex protein 0.0016 0.0004 0.0007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0066 0.0066
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0086
Loa Loa (eye worm) DR-78 0.0039 0.0073 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0066 0.0113
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.0021 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Brugia malayi CXXC zinc finger family protein 0.0059 0.0131 0.0223
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0001 0.0031
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0073 0.0075
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0031 0.0051 0.0215
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0293
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.0021 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0242 0.0242
Onchocerca volvulus 0.0392 0.1115 0.4979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0012 0.006
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Echinococcus granulosus histone acetyltransferase MYST2 0.0098 0.0248 0.0248
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Brugia malayi CHE-14 protein 0.0096 0.0241 0.041
Echinococcus multilocularis smad 0.0024 0.0028 0.0028
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Mycobacterium ulcerans esterase/lipase LipP 0.0025 0.0031 0.0757
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus multilocularis isocitrate dehydrogenase 0.0023 0.0025 0.0025
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0036 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.0005
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Brugia malayi RNA binding protein 0.0241 0.0667 0.1136
Giardia lamblia TCP-1 chaperonin subunit beta 0.0017 0.0007 0.0037
Echinococcus granulosus importin subunit beta 1 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Schistosoma mansoni lamin 0.002 0.0018 0.0031
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0042
Brugia malayi cathepsin F-like cysteine proteinase 0.011 0.0284 0.0483
Schistosoma mansoni transcription factor LCR-F1 0.0132 0.0348 0.0593
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0025 0.0031 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0055 0.027
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0147 0.0147
Echinococcus multilocularis SAM and MBT domain containing protein 0.0086 0.0213 0.0213
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0023 0.0025 0.0586
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Entamoeba histolytica cysteine proteinase, putative 0.0392 0.1115 1
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Onchocerca volvulus 0.0038 0.0071 0.0312
Brugia malayi tailless protein 0.0039 0.0073 0.0125
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0016
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.023 0.0637 0.1085
Schistosoma mansoni cathepsin C 0.012 0.0312 0.0531
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0414 0.9752
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0241 0.0667 0.0682
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0037
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.002 0.002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0028 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus multilocularis importin subunit beta 1 0.0043 0.0084 0.0084
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0025 0.0031 0.0032
Schistosoma mansoni hypothetical protein 0.0454 0.1297 0.2207
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0083 0.0203 0.0208
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Schistosoma mansoni lamin 0.002 0.0018 0.0031
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.0048
Brugia malayi RNA recognition motif domain containing protein 0.0241 0.0667 0.1136
Echinococcus multilocularis tumor protein p63 0.0261 0.0729 0.0729
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Plasmodium falciparum serine repeat antigen 5 0.012 0.0312 0.2753
Echinococcus multilocularis cysteine protease 0.0392 0.1115 0.1115
Schistosoma mansoni hypothetical protein 0.0529 0.1516 0.258
Echinococcus granulosus tumor protein p63 0.0261 0.0729 0.0729
Plasmodium falciparum phd finger protein, putative 0.0021 0.0021 0.0128
Loa Loa (eye worm) mbt repeat family protein 0.0086 0.0213 0.0217
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Brugia malayi beta-lactamase family protein 0.0025 0.0031 0.0053
Schistosoma mansoni alpha glucosidase 0.0037 0.0066 0.0113
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0242 0.0247
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0023 0.0025 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Echinococcus granulosus polycomb protein SCMH1 0.0086 0.0213 0.0213
Onchocerca volvulus 0.0025 0.0031 0.0134
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0086 0.0213 0.0362
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Brugia malayi fibroinase precursor 0.012 0.0312 0.0531
Giardia lamblia Encystation-specific protease 0.012 0.0312 0.1535
Entamoeba histolytica cysteine protease, putative 0.0392 0.1115 1
Echinococcus granulosus cathepsin L 0.012 0.0312 0.0312
Giardia lamblia Cathepsin L-like protease 0.012 0.0312 0.1535
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Brugia malayi STAT protein, DNA binding domain containing protein 0.0141 0.0373 0.0635
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0012 0.0046
Loa Loa (eye worm) runx1 0.0059 0.0134 0.0136
Leishmania major importin beta-1 subunit, putative 0.0035 0.006 0.0295
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0025 0.0031 0.0738
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0141 0.0141
Plasmodium vivax importin-beta 2, putative 0.0043 0.0084 0.0692
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0202 0.0206
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0001 0.0012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0012 0.0295
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0062 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0202 0.0344
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0042 0.0082 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Brugia malayi MAP kinase sur-1 0.0039 0.0075 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0107
Mycobacterium ulcerans hypothetical protein 0.0025 0.0031 0.0757
Mycobacterium tuberculosis Probable esterase LipL 0.0025 0.0031 0.0738
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0088
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0022
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Echinococcus multilocularis cathepsin b 0.2008 0.5875 0.5875
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Brugia malayi nuclear receptor NHR-67 0.0039 0.0073 0.0125
Trypanosoma cruzi cruzipain precursor, putative 0.011 0.0284 0.0483
Echinococcus granulosus Protein patched homolog 1 0.0096 0.0241 0.0241
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0312 0.0319
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0073 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.023 0.0637 0.3136
Giardia lamblia Kinase, CMGC MAPK 0.0039 0.0075 0.0367
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0344 0.0972 0.0972
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0086 0.0213 0.0946
Echinococcus granulosus geminin 0.0621 0.1787 0.1787
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0202 0.0344
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0445 0.0758
Echinococcus granulosus histone lysine methyltransferase setb 0.0108 0.0277 0.0277
Echinococcus granulosus mitogen activated protein kinase 0.0039 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0835 0.242 0.4118
Loa Loa (eye worm) hypothetical protein 0.0239 0.0663 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0704 0.2033 1
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.023 0.0637 0.3136
Echinococcus multilocularis cysteine protease 0.0392 0.1115 0.1115
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Loa Loa (eye worm) hypothetical protein 0.0124 0.0325 0.0331
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0007 0.0012
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0124 0.0325 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.008 0.0136
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0202 0.0897
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0293
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0465 0.1327 0.1356
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Plasmodium vivax unspecified product 0.011 0.0284 0.2498
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0031 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Schistosoma mansoni myelin transcription factor 1 myt1 0.0098 0.0248 0.0422
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0163 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0088
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0704 0.2033 0.9878
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0039 0.0075 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.0406
Schistosoma mansoni DNA polymerase eta 0.0033 0.0055 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Entamoeba histolytica serine/threonine protein kinase, putative 0.007 0.0163 0.1464
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Trypanosoma brucei glucosidase, putative 0.0037 0.0066 0.0327
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0284 0.029
Schistosoma mansoni zinc finger protein 0.0023 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0704 0.2033 0.346
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0036 0.0062
Giardia lamblia Cathepsin L-like protease 0.012 0.0312 0.1535
Brugia malayi Isocitrate dehydrogenase 0.0023 0.0025 0.0042
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Schistosoma mansoni zinc finger protein 0.0016 0.0004 0.0007
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0073 0.0073
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Brugia malayi beta-lactamase 0.0025 0.0031 0.0053
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0066 0.0113
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0344 0.0972 0.0972
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0096 0.0241 0.0246
Trypanosoma cruzi ISWI complex protein 0.0016 0.0004 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Schistosoma mansoni ap endonuclease 0.0018 0.0012 0.0021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0087 0.0087
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0202 0.0344
Brugia malayi Fz domain containing protein 0.007 0.0166 0.0282
Onchocerca volvulus Cathepsin L homolog 0.012 0.0312 0.139
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0202 0.0202
Echinococcus multilocularis frizzled 0.0154 0.0411 0.0411
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Trichomonas vaginalis ran, putative 0.0031 0.0051 0.0246
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0312 0.0531
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0157 0.016
Echinococcus multilocularis mitogen activated protein kinase 3 0.0039 0.0075 0.0075
Echinococcus multilocularis secreted frizzled protein 0.007 0.0166 0.0166
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.012 0.0312 0.2753
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2008 0.5875 1
Echinococcus granulosus Niemann Pick C1 protein 0.032 0.09 0.09
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0098 0.0248 0.0253
Trichomonas vaginalis esterase, putative 0.0025 0.0031 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.042
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0017 0.0007 0.0036
Loa Loa (eye worm) hypothetical protein 0.035 0.0989 0.101
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0041 0.008 0.0082
Schistosoma mansoni hypothetical protein 0.0621 0.1787 0.3041
Schistosoma mansoni sex comb on midleg homolog 0.0086 0.0213 0.0362
Entamoeba histolytica cysteine proteinase 2 0.023 0.0637 0.5719
Onchocerca volvulus 0.0039 0.0073 0.0322
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0031 0.0051 0.0051
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0106 0.0271 0.0271
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0227 0.0627 0.1068
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0025 0.0031 0.0738
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0857 0.0857
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0012 0.0012
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0202 0.0344
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.011 0.0284 0.0483
Trypanosoma cruzi importin beta-1 subunit, putative 0.0035 0.006 0.0102
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Brugia malayi isocitrate dehydrogenase 0.0023 0.0025 0.0042
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0049 0.0213
Toxoplasma gondii preprocathepsin c precursor, putative 0.012 0.0312 0.1506
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.0021 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0226 0.0385
Echinococcus multilocularis frizzled 5 0.0154 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.0109 0.0111
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Onchocerca volvulus Cathepsin L homolog 0.0392 0.1115 0.4979
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0007 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Onchocerca volvulus 0.007 0.0166 0.0736
Toxoplasma gondii ABC1 family protein 0.0025 0.0031 0.012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0031 0.0799
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0637 0.1085
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Echinococcus multilocularis secreted frizzled protein 0.007 0.0166 0.0166
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0047 0.008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0393
Echinococcus granulosus chromobox protein 1 0.0051 0.0109 0.0109
Leishmania major basic transcription factor 3a, putative 0.0026 0.0036 0.0178
Trypanosoma cruzi cysteine protease, putative 0.023 0.0637 0.1085
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0007 0.0007
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Echinococcus multilocularis smoothened 0.3408 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0202 0.0206
Brugia malayi cathepsin F-like cysteine proteinase 0.012 0.0312 0.0531
Echinococcus multilocularis cathepsin L cysteine protease 0.0392 0.1115 0.1115
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.014
Brugia malayi Niemann-Pick C1 protein precursor 0.0224 0.0617 0.1051
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Mycobacterium tuberculosis Probable hydrolase 0.0025 0.0031 0.0738
Plasmodium vivax vivapain-1 0.023 0.0637 0.5691
Plasmodium vivax vivapain-2 0.0392 0.1115 1
Brugia malayi Muscleblind-like protein 0.0305 0.0857 0.1459
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0099 0.0251 0.0427
Brugia malayi Pre-SET motif family protein 0.0626 0.1803 0.3069
Echinococcus multilocularis cathepsin b 0.2008 0.5875 0.5875
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0028 0.0028
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0066 0.0066
Schistosoma mansoni Smad4 0.0024 0.0028 0.0048
Echinococcus multilocularis expressed conserved protein 0.021 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0046 0.0095 0.0097
Trypanosoma cruzi cysteine proteinase, putative 0.023 0.0637 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Toxoplasma gondii hypothetical protein 0.0047 0.0098 0.0448
Loa Loa (eye worm) fibroinase 0.0392 0.1115 0.1138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Brugia malayi steroid hormone receptor 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0173 0.0468 0.0478
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.012 0.0312 0.2753
Brugia malayi hypothetical protein 0.0039 0.0073 0.0125
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0158 0.0425 1
Mycobacterium tuberculosis Probable lipase LipD 0.0025 0.0031 0.0738
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0312 0.2753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Schistosoma mansoni alpha-glucosidase 0.0142 0.0377 0.0643
Schistosoma mansoni transcription factor btf3 0.0026 0.0036 0.0062
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0202 0.0344
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0012 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Echinococcus granulosus cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Schistosoma mansoni microtubule-associated protein tau 0.0521 0.1494 0.2543
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Schistosoma mansoni survival motor neuron protein 0.0035 0.0062 0.0106
Loa Loa (eye worm) hypothetical protein 0.0224 0.0617 0.063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0107
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0087 0.0087
Leishmania major DNA polymerase eta, putative 0.0033 0.0055 0.027
Onchocerca volvulus 0.0025 0.0031 0.0134
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0249
Brugia malayi Importin beta-1 subunit 0.0043 0.0084 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0031 0.0053
Schistosoma mansoni hypothetical protein 0.0069 0.0161 0.0275
Echinococcus granulosus Niemann Pick C1 protein 0.0224 0.0617 0.0617
Echinococcus granulosus survival motor neuron protein 1 0.0173 0.0468 0.0468
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0132 0.0651
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0035
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0312 0.0531
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0284 0.0284
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0021 0.007
Brugia malayi Bromodomain containing protein 0.0024 0.0028 0.0048
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0226 0.1082
Onchocerca volvulus 0.0096 0.024 0.1067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Loa Loa (eye worm) hypothetical protein 0.0118 0.0305 0.0311
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Mycobacterium tuberculosis Probable lipase LipE 0.0025 0.0031 0.0738
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0202 0.0344
Echinococcus multilocularis thyroid hormone receptor alpha 0.0083 0.0202 0.0202
Loa Loa (eye worm) MH2 domain-containing protein 0.0348 0.0983 0.1004
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Brugia malayi chromobox protein homolog 3 0.0029 0.0043 0.0073
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0031 0.0051 0.0393
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0284 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Echinococcus multilocularis neuropeptide receptor A26 0.0607 0.1747 0.1747
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0073 0.0322
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.012 0.0312 0.2753
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0031 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0312 0.1517
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0293
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Brugia malayi cahepsin L-like non-peptiedase homolog 0.012 0.0312 0.0531
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0073 0.0322
Loa Loa (eye worm) pigment dispersing factor receptor c 0.035 0.0989 0.101
Echinococcus granulosus muscleblind protein 0.0305 0.0857 0.0857
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0202 0.0344
Echinococcus granulosus peregrin 0.0024 0.0028 0.0028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.006 0.0292
Plasmodium falciparum serine repeat antigen 8 0.012 0.0312 0.2753
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0242 0.0412
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.012 0.0312 0.0319
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0025 0.0031 0.0757
Brugia malayi hypothetical protein 0.0173 0.0468 0.0796
Onchocerca volvulus 0.0282 0.0789 0.3524
Plasmodium falciparum importin beta, putative 0.0043 0.0084 0.0692
Loa Loa (eye worm) papain family cysteine protease containing protein 0.011 0.0284 0.029
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0596
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Echinococcus multilocularis lamin dm0 0.002 0.0018 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.008 0.0136
Brugia malayi Cathepsin L-like precursor 0.011 0.0284 0.0483
Loa Loa (eye worm) hypothetical protein 0.0392 0.1115 0.1138
Plasmodium falciparum serine repeat antigen 2 0.012 0.0312 0.2753
Toxoplasma gondii cathepsin CPL 0.0392 0.1115 0.5469
Echinococcus multilocularis microtubule associated protein 2 0.0521 0.1494 0.1494
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0083 0.0203 0.0346
Brugia malayi cathepsin L-like precursor 0.0282 0.0789 0.1344
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0073 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0073 0.0125
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0098 0.0248 0.0422
Brugia malayi MH2 domain containing protein 0.0348 0.0983 0.1674
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus granulosus cpg binding protein 0.0064 0.0147 0.0147
Loa Loa (eye worm) MBCTL1 0.0098 0.0248 0.0253
Schistosoma mansoni lozenge 0.0059 0.0134 0.0227
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0084 0.0412
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0028 0.0048
Loa Loa (eye worm) hypothetical protein 0.0305 0.0857 0.0875
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0073 0.0073
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0049 0.0238
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0023 0.0025 0.0042
Echinococcus granulosus secreted frizzled protein 5 0.007 0.0166 0.0166
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0147 0.0147
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0163 0.0278
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Loa Loa (eye worm) intermediate filament protein 0.002 0.0018 0.0019
Onchocerca volvulus 0.0392 0.1115 0.4979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0789 0.3836
Brugia malayi intermediate filament protein 0.002 0.0018 0.0031
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0066 0.0327
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2399 0.7027 0.7027
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0042 0.0082 0.014
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0312 0.1517
Schistosoma mansoni nuclear receptor 0.0039 0.0073 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0015 0.0001 0.0032
Loa Loa (eye worm) STAT protein 0.0141 0.0373 0.0381
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0026 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0073 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0202 0.0344
Brugia malayi hypothetical protein 0.0774 0.2238 0.3809
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0028 0.0028
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0202 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0075 0.0127
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0031 0.0053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0202 0.0344
Brugia malayi jmjC domain containing protein 0.0106 0.0271 0.0461
Echinococcus granulosus cathepsin L cysteine protease 0.023 0.0637 0.0637
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0816 0.7316
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0066 0.0066
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.012 0.0312 0.2753
Schistosoma mansoni ran 0.0031 0.0051 0.0086
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Onchocerca volvulus 0.0099 0.0251 0.1116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Schistosoma mansoni chromobox protein 0.0051 0.0109 0.0185
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0249
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0202 0.0202
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0073 0.0125
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0007 0.0007
Schistosoma mansoni frizzled-like receptor 0.0083 0.0203 0.0346
Schistosoma mansoni cathepsin S (C01 family) 0.012 0.0312 0.0531
Echinococcus granulosus cathepsin l1 0.0392 0.1115 0.1115
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.012 0.0312 0.1517
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0106 0.0271 0.0271
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0073 0.0125
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0284 0.0484
Toxoplasma gondii cathepsin CPC2 0.012 0.0312 0.1506
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0042 0.0082 0.0739
Onchocerca volvulus 0.0392 0.1115 0.4979
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0031 0.0219
Echinococcus multilocularis dnaJ subfamily B 0.0835 0.242 0.242
Schistosoma mansoni nuclear receptor 0.0039 0.0073 0.0125
Plasmodium vivax unspecified product 0.023 0.0637 0.5691
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0042 0.0082 0.0406
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0202 0.0344
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0157 0.0267
Schistosoma mansoni hypothetical protein 0.0239 0.0663 0.1128
Schistosoma mansoni cathepsin F (C01 family) 0.0392 0.1115 0.1897
Mycobacterium ulcerans lipase LipD 0.0025 0.0031 0.0757
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0454 0.1297 0.1324
Plasmodium falciparum serine repeat antigen 4 0.012 0.0312 0.2753
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Echinococcus granulosus transcription factor btf3 0.0026 0.0036 0.0036
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.008 0.0136
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0202 0.0202
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0392 0.1115 1
Onchocerca volvulus 0.0392 0.1115 0.4979
Brugia malayi mbt repeat family protein 0.0086 0.0213 0.0362
Loa Loa (eye worm) hypothetical protein 0.0086 0.0213 0.0217
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.008 0.0394
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0132 0.0348 0.0348
Echinococcus granulosus cathepsin L cysteine proteinase 0.0392 0.1115 0.1115
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0007 0.0013
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0055 0.0094
Schistosoma mansoni hypothetical protein 0.0035 0.0062 0.0106
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0241 0.1172
Echinococcus granulosus cathepsin b 0.2008 0.5875 0.5875
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0312 0.2799
Brugia malayi ecdysteroid receptor 0.0083 0.0202 0.0344
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0018 0.0031
Plasmodium vivax SET domain protein, putative 0.0091 0.0226 0.1979
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0073 0.0073
Schistosoma mansoni kinase 0.0036 0.0063 0.0107
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0073 0.0125
Echinococcus granulosus dnaJ subfamily B 0.0835 0.242 0.242
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0392 0.1115 0.1138
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Echinococcus granulosus expressed conserved protein 0.021 0.0577 0.0577
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0242 0.0242
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0474 0.1355 0.1384
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Brugia malayi Papain family cysteine protease containing protein 0.0392 0.1115 0.1897
Loa Loa (eye worm) hypothetical protein 0.2008 0.5875 0.6
Brugia malayi latrophilin 2 splice variant baaae 0.0239 0.0663 0.1128
Plasmodium vivax vivapain-3 0.023 0.0637 0.5691
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0017 0.0007 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0039 0.0075 0.0334
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0132 0.0132
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Loa Loa (eye worm) hypothetical protein 0.0111 0.0284 0.029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0087 0.0148
Echinococcus multilocularis musashi 0.002 0.0018 0.0018
Toxoplasma gondii HEAT repeat-containing protein 0.0043 0.0084 0.0378
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.006 0.0292
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0596
Leishmania major cysteine peptidase A (CPA) 0.0392 0.1115 0.5484
Echinococcus multilocularis protein dispatched 1 0.011 0.0281 0.0281
Onchocerca volvulus Cathepsin L homolog 0.0392 0.1115 0.4979
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Toxoplasma gondii t-complex protein beta subunit 0.0017 0.0007 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0012
Brugia malayi nuclear receptor NHR-88 0.0083 0.0202 0.0344
Onchocerca volvulus 0.0086 0.0213 0.0946
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Giardia lamblia Hypothetical protein 0.012 0.0312 0.1535
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0044
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0036 0.0036
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0012 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.0277 0.0472
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0015 0.0001 0.0032
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0202 0.0206
Echinococcus granulosus serine:threonine protein kinase PLK1 0.007 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0072 0.017 0.0173
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0284 0.0284
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0073 0.0073
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0007 0.0007
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0036 0.0061
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0039 0.0075 0.0367
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0392 0.1115 0.1138
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0007 0.0007
Schistosoma mansoni coup transcription factor 0.0083 0.0202 0.0344
Echinococcus granulosus frizzled 4 0.0154 0.0411 0.0411
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.0699
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0305 0.0857 0.0875
Schistosoma mansoni zinc finger protein 0.0039 0.0073 0.0125
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Schistosoma mansoni cathepsin s 0.011 0.0284 0.0483
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0073 0.0073
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.012 0.0312 0.0531
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Brugia malayi Smad1 0.0024 0.0028 0.0048
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.0823 0.4051
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0202 0.0202
Echinococcus granulosus chromobox protein 1 0.0051 0.0109 0.0109
Echinococcus granulosus snurportin 1 0.0454 0.1297 0.1297
Echinococcus multilocularis protein patched 0.0096 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus jumonji domain containing protein 0.003 0.0046 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0017 0.0007 0.0067
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0021 0.007
Echinococcus multilocularis neuropeptide s receptor 0.0607 0.1747 0.1747
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0242 0.0242
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0052
Echinococcus granulosus SAM and MBT domain containing protein 0.0086 0.0213 0.0213
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0012 0.011
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.012 0.0312 0.2753
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis frizzled 0.0154 0.0411 0.0411
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Echinococcus multilocularis peregrin 0.0024 0.0028 0.0028
Schistosoma mansoni chromobox protein 0.0051 0.0109 0.0185
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Brugia malayi hypothetical protein 0.0044 0.0087 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0202 0.0344
Echinococcus granulosus neuropeptide receptor A26 0.0607 0.1747 0.1747
Echinococcus granulosus Smad4 0.0024 0.0028 0.0028
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0039 0.0075 0.0367
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0132 0.0225
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0023 0.0023
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0073 0.0075
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0368 0.1809
Trypanosoma brucei RNA helicase, putative 0.0069 0.0161 0.0794
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0202 0.0344
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0066 0.0323
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0368 0.1809
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.0277 0.0472
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.0699
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0036 0.0263
Schistosoma mansoni secreted frizzled-related protein 0.007 0.0166 0.0282
Brugia malayi PHD-finger family protein 0.0029 0.0043 0.0073
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0021 0.0022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0213 0.0213
Onchocerca volvulus Huntingtin homolog 0.0124 0.0325 0.1445
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0075 0.0127
Giardia lamblia Hypothetical protein 0.012 0.0312 0.1535
Trichomonas vaginalis importin beta-1, putative 0.0035 0.006 0.0292
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0012 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0019
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2008 0.5875 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.007 0.0163 0.0163
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0312 0.0531
Brugia malayi Bromodomain containing protein 0.0039 0.0073 0.0124
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0073 0.0125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0022
Giardia lamblia Kinase, PLK 0.007 0.0163 0.0803
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0025 0.0088
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0704 0.2033 0.346
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0202 0.0206
Onchocerca volvulus 0.0022 0.0024 0.0103
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0025 0.0088
Brugia malayi follicle stimulating hormone receptor 0.0465 0.1327 0.2259
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0312 0.2753
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0224 0.0617 0.5537
Brugia malayi Calcitonin receptor-like protein seb-1 0.035 0.0989 0.1683
Onchocerca volvulus 0.012 0.0312 0.139
Schistosoma mansoni hypothetical protein 0.0021 0.0021 0.0036
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0012 0.006
Brugia malayi beta-lactamase family protein 0.0025 0.0031 0.0053
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.035 0.0989 0.1683
Mycobacterium ulcerans hypothetical protein 0.0015 0.0001 0.0032
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Leishmania major DNA polymerase eta, putative 0.0023 0.0026 0.0129
Echinococcus granulosus phd:f box containing protein 0.0017 0.0007 0.0007
Onchocerca volvulus Serine\/threonine kinase homolog 0.007 0.0163 0.0724
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0073 0.0125
Brugia malayi Cathepsin L-like precursor 0.0282 0.0789 0.1344
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0098 0.0248 0.0248
Schistosoma mansoni patched 1 0.0096 0.0241 0.041
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0202 0.0344
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0075 0.0127
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.012 0.0312 0.2753
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0073 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis mitogen activated protein kinase 0.0039 0.0075 0.0075
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0031 0.0152
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Brugia malayi Cathepsin L-like precursor 0.0282 0.0789 0.1344
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Schistosoma mansoni cpg binding protein 0.0059 0.0131 0.0223
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0066 0.0323
Onchocerca volvulus Huntingtin homolog 0.0124 0.0325 0.1445
Echinococcus multilocularis secreted frizzled protein 5 0.007 0.0166 0.0166
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0335 0.057
Schistosoma mansoni wnt inhibitor frzb2 0.007 0.0166 0.0282
Echinococcus multilocularis transcription factor btf3 0.0026 0.0036 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0036 0.0178
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Schistosoma mansoni ap endonuclease 0.0018 0.0012 0.0021
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.0823 0.4051
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0073 0.0125
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Leishmania major GTP-binding protein, putative 0.0031 0.0051 0.0249
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.0528
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0087 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0202 0.0344
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0202 0.0344
Brugia malayi cathepsin B-like cysteine proteinase 0.2008 0.5875 1
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0017 0.0007 0.0003
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Echinococcus multilocularis geminin 0.0621 0.1787 0.1787
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0157 0.0157
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0282 0.0789 0.1344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Onchocerca volvulus 0.0774 0.2238 1
Echinococcus granulosus GPCR family 2 0.0111 0.0284 0.0284
Echinococcus multilocularis chromobox protein 1 0.0051 0.0109 0.0109
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0023 0.0025 0.0122
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Trypanosoma cruzi cysteine peptidase, putative 0.023 0.0637 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0789 0.3836
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0312 0.2799
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.012 0.0312 0.2753
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Loa Loa (eye worm) hypothetical protein 0.0096 0.0241 0.0246
Schistosoma mansoni cathepsin B (C01 family) 0.012 0.0312 0.0531
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus granulosus smad 0.0024 0.0028 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0004 0.0019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0312 0.0319
Echinococcus multilocularis chromobox protein 1 0.0051 0.0109 0.0109
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0036 0.0036
Schistosoma mansoni alpha-glucosidase 0.0142 0.0377 0.0643
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0392 0.1115 1
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0055 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0036 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) cathepsin B 0.0704 0.2033 0.2076
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Brugia malayi PHD-finger family protein 0.0021 0.0021 0.0036
Mycobacterium leprae Probable lipase LipE 0.0025 0.0031 0.0799
Brugia malayi jmjC domain containing protein 0.0067 0.0157 0.0267
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0043 0.0185
Echinococcus granulosus GTP binding nuclear protein Ran 0.0031 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Loa Loa (eye worm) cysteine protease 0.0392 0.1115 0.1138
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0028 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.0073
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Brugia malayi nuclear receptor RXR 0.0044 0.0087 0.0148
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0049 0.0238
Echinococcus multilocularis cathepsin L 0.023 0.0637 0.0637
Plasmodium vivax unspecified product 0.012 0.0312 0.2753
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Echinococcus multilocularis Smad4 0.0024 0.0028 0.0028
Brugia malayi Bromodomain containing protein 0.0079 0.0192 0.0327
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.012 0.0312 0.1535
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0088 0.009
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.0528
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Onchocerca volvulus 0.0474 0.1355 0.6053
Entamoeba histolytica hypothetical protein 0.012 0.0312 0.2799
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0284 0.0284
Onchocerca volvulus Cathepsin F homolog 0.0392 0.1115 0.4979
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0039 0.0075 0.0367
Plasmodium falciparum serine repeat antigen 1 0.012 0.0312 0.2753
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0202 0.0897
Loa Loa (eye worm) hypothetical protein 0.007 0.0166 0.0169
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.012 0.0312 0.2753
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0202 0.0897
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0377 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0066 0.0113
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Onchocerca volvulus 0.0392 0.1115 0.4979
Loa Loa (eye worm) ctsf protein 0.0392 0.1115 0.1138
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0073 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Echinococcus granulosus cysteine protease 0.023 0.0637 0.0637
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0202 0.0206
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0042 0.0082 0.0082
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0036 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0202 0.0344
Brugia malayi nuclear receptor RXR 0.0039 0.0073 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0015 0.0001 0.0032
Plasmodium falciparum serine repeat antigen 9 0.012 0.0312 0.2753
Brugia malayi hypothetical protein 0.0132 0.0348 0.0593
Trypanosoma brucei polo-like protein kinase 0.007 0.0163 0.0803
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0084 0.0412
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.012 0.0312 0.2753
Schistosoma mansoni cathepsin F (C01 family) 0.0282 0.0789 0.1344
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0823 0.1401
Echinococcus multilocularis Protein lozenge 0.0059 0.0134 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0087 0.0148
Entamoeba histolytica acyl-coA synthetase, putative 0.0015 0.0001 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0637 0.3098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0012 0.0059
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0445 0.0455
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0202 0.0344
Toxoplasma gondii cathepsin CPC1 0.012 0.0312 0.1506
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0032 0.0054
Giardia lamblia PHD finger protein 15 0.0021 0.0021 0.0105
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0012 0.0288
Brugia malayi hypothetical protein 0.0039 0.0073 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Brugia malayi nuclear hormone receptor 0.0039 0.0073 0.0125
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0066 0.0323
Trichomonas vaginalis set domain proteins, putative 0.0713 0.2058 1
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0025 0.0031 0.0738
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0031 0.0053
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0066 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Onchocerca volvulus 0.0025 0.0031 0.0134
Schistosoma mansoni frizzled 0.0154 0.0411 0.0699
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Echinococcus multilocularis tar DNA binding protein 0.0241 0.0667 0.0667
Echinococcus granulosus transcription factor Dp 1 0.0024 0.003 0.003
Schistosoma mansoni cellular tumor antigen P53 0.0038 0.0071 0.0121
Echinococcus multilocularis cpg binding protein 0.0064 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0774 0.2238 0.2285
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0132 0.0132
Onchocerca volvulus 0.0039 0.0073 0.0322
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0066 0.0323
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0025 0.0031 0.0053
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0098 0.0248 0.0248
Onchocerca volvulus 0.002 0.0018 0.0076
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0312 0.0531
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0202 0.0344
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.012 0.0312 0.1517
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0132 0.0618
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0816 0.7316
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0023 0.0023
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0202 0.0202
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Echinococcus multilocularis frizzled 4 0.0154 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.3338 0.9792 1
Brugia malayi cathepsin L-like cysteine proteinase 0.012 0.0312 0.0531
Onchocerca volvulus 0.002 0.0018 0.0076
Onchocerca volvulus 0.0035 0.0062 0.0273
Schistosoma mansoni cpg binding protein 0.0064 0.0147 0.025
Echinococcus multilocularis histone acetyltransferase MYST2 0.0098 0.0248 0.0248
Schistosoma mansoni ran 0.0031 0.0051 0.0086
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0017 0.0007 0.0007
Onchocerca volvulus 0.0392 0.1115 0.4979
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0132 0.3116
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0637 0.1085
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0202 0.0202
Echinococcus multilocularis survival motor neuron protein 1 0.0173 0.0468 0.0468
Brugia malayi beta-NAC-like protein 0.0026 0.0036 0.0062
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0007 0.0012
Brugia malayi Pre-SET motif family protein 0.0091 0.0226 0.0385
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0303 0.1459
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0202 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0012 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0132 0.0225
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0122
Loa Loa (eye worm) Smad1 0.0024 0.0028 0.0029
Trypanosoma cruzi cysteine proteinase, putative 0.023 0.0637 0.1085
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Brugia malayi MH2 domain containing protein 0.0024 0.0028 0.0048
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Loa Loa (eye worm) hypothetical protein 0.0108 0.0277 0.0283
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Entamoeba histolytica cysteine proteinase, putative 0.0392 0.1115 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.014
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0163 0.0278
Echinococcus granulosus neuropeptide s receptor 0.0607 0.1747 0.1747
Echinococcus granulosus cathepsin l1 0.0282 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Mycobacterium ulcerans beta-lactamase 0.0025 0.0031 0.0757
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Brugia malayi hypothetical protein 0.0044 0.0087 0.0148
Echinococcus granulosus dna polymerase eta 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.007 0.0166 0.0169
Echinococcus granulosus intermediate filament protein 0.002 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0637 0.3098
Echinococcus multilocularis frizzled 10 0.0154 0.0411 0.0411
Echinococcus multilocularis transcription factor Dp 1 0.0024 0.003 0.003
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Echinococcus granulosus zinc finger protein 0.0023 0.0027 0.0027
Brugia malayi hypothetical protein 0.0474 0.1355 0.2306
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0073 0.0125
Mycobacterium ulcerans hypothetical protein 0.0155 0.0414 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0108 0.0277 0.0277
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0131 0.0134
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0039 0.0075 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0086
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Brugia malayi TAR-binding protein 0.0241 0.0667 0.1136
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Toxoplasma gondii exonuclease III APE 0.0018 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.007 0.0163 0.0803
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0626 0.1803 0.1842
Schistosoma mansoni intermediate filament proteins 0.002 0.0018 0.0031
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0042 0.0082 0.014
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0036 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.012 0.0312 0.2753
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0012 0.0012
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0312 0.0531
Brugia malayi cathepsin L precursor 0.012 0.0312 0.0531
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0202 0.0344
Echinococcus granulosus cathepsin b 0.2008 0.5875 0.5875
Entamoeba histolytica hypothetical protein 0.0026 0.0036 0.0324
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Plasmodium falciparum T-complex protein 1 subunit beta 0.0017 0.0007 0.0003
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0066 0.0066
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0042 0.0082 0.0084
Brugia malayi Fz domain containing protein 0.007 0.0166 0.0282
Plasmodium falciparum serine repeat antigen 7 0.012 0.0312 0.2753
Trypanosoma brucei cysteine peptidase C (CPC) 0.0704 0.2033 1
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Plasmodium falciparum cysteine proteinase falcipain 1 0.023 0.0637 0.5691
Schistosoma mansoni importin beta-1 0.0043 0.0084 0.0143
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Onchocerca volvulus 0.0392 0.1115 0.4979
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0202 0.0344
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.012 0.0312 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0202 0.0202
Onchocerca volvulus 0.0059 0.0131 0.0581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.0816 1
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0007 0.0012
Leishmania major hypothetical protein, conserved 0.0017 0.0007 0.0035
Brugia malayi RNA, U transporter 1 0.0121 0.0315 0.0536
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0039 0.0075 0.0127
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Entamoeba histolytica Ran family GTPase 0.0031 0.0051 0.0454
Echinococcus multilocularis polycomb protein SCMH1 0.0086 0.0213 0.0213
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0284 0.0483
Brugia malayi hypothetical protein 0.0124 0.0325 0.0552
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Echinococcus multilocularis sterol regulatory element binding protein 0.0096 0.0241 0.0241
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0087 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0377 0.8883
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0043 0.0207
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0284 0.0284
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0312 0.2753
Brugia malayi conserved hypotetical protein 0.0039 0.0073 0.0125
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0312 0.2753
Trichomonas vaginalis chaperonin, putative 0.0017 0.0007 0.0036
Schistosoma mansoni frizzled-like receptor 0.0154 0.0411 0.0699
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0202 0.0344
Brugia malayi serine/threonine-protein kinase plk-2 0.007 0.0163 0.0278
Echinococcus multilocularis cathepsin L 0.012 0.0312 0.0312
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0012 0.006
Schistosoma mansoni cathepsin F (C01 family) 0.0392 0.1115 0.1897
Echinococcus granulosus microtubule associated protein 2 0.0521 0.1494 0.1494
Toxoplasma gondii cathepsin B 0.0704 0.2033 1
Trypanosoma brucei ISWI complex protein 0.0016 0.0004 0.002
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0007 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0012 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Onchocerca volvulus Alhambra homolog 0.0021 0.0021 0.0089
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0157 0.0267
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0028 0.0028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0012
Schistosoma mansoni cpg binding protein 0.0064 0.0147 0.025
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0202 0.0202
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0132 0.0348 0.0348
Echinococcus multilocularis Niemann Pick C1 protein 0.032 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.0282 0.0789 0.7081
Plasmodium falciparum serine repeat antigen 3 0.012 0.0312 0.2753
Echinococcus multilocularis Niemann Pick C1 protein 0.0224 0.0617 0.0617
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0202 0.0206
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0107 0.0181
Trypanosoma brucei protein kinase, putative 0.0039 0.0075 0.0367
Loa Loa (eye worm) hypothetical protein 0.0047 0.0096 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0021 0.0128
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0202 0.0344
Echinococcus multilocularis lamin 0.002 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0087 0.0089
Schistosoma mansoni hypothetical protein 0.0021 0.002 0.0034
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0015 0.0001 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0202 0.0206
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0001 0.0012
Echinococcus granulosus mitogen activated protein kinase 3 0.0039 0.0075 0.0075
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Echinococcus granulosus frizzled 5 0.0154 0.0411 0.0411
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.012 0.0312 0.2753
Loa Loa (eye worm) T-complex protein 1 0.0017 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Echinococcus granulosus lamin dm0 0.002 0.0018 0.0018
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0007 0.0007
Echinococcus multilocularis GPCR, family 2 0.0111 0.0284 0.0284
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0023 0.0025 0.0042
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0011 0.0011
Echinococcus granulosus sterol regulatory element binding protein 0.0096 0.0241 0.0241
Schistosoma mansoni hypothetical protein 0.0132 0.0348 0.0593

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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