Detailed information for compound 914236

Basic information

Technical information
  • TDR Targets ID: 914236
  • Name: N-(3-chlorophenyl)-6,7-dimethoxy-N-methylquin azolin-4-amine hydrochloride
  • MW: 366.242 | Formula: C17H17Cl2N3O2
  • H donors: 0 H acceptors: 2 LogP: 4.93 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cc1OC)ncnc2N(c1cccc(c1)Cl)C.Cl
  • InChi: 1S/C17H16ClN3O2.ClH/c1-21(12-6-4-5-11(18)7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17;/h4-10H,1-3H3;1H
  • InChiKey: HJAAVYKVKNFYNJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-chlorophenyl)-6,7-dimethoxy-N-methyl-quinazolin-4-amine hydrochloride
  • N-(3-chlorophenyl)-6,7-dimethoxy-N-methyl-4-quinazolinamine hydrochloride
  • (3-chlorophenyl)-(6,7-dimethoxyquinazolin-4-yl)-methyl-amine hydrochloride

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epidermal growth factor receptor Starlite/ChEMBL No references
Homo sapiens colony stimulating factor 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus melanoma receptor tyrosine protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum IPR006212,Furin-like repeat;IPR009030,Growth factor, receptor,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-2 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128597 All targets in OG5_128597
Brugia malayi Furin-like cysteine rich region family protein Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum IPR000494,EGF receptor, L domain,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Loa Loa (eye worm) TK/EGFR protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-4 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum expressed protein Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum ko:K05085 receptor tyrosine-protein kinase erbB-4, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Tyrosine-protein kinase transforming protein erbB, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus macrophage colony stimulating factor 1 receptor Get druggable targets OG5_132967 All targets in OG5_132967
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni polycystin 1-related 0.0048 0.0203 0.0221
Schistosoma mansoni hypothetical protein 0.0353 0.1986 0.2208
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0107 0.0102
Onchocerca volvulus 0.0101 0.0514 0.1091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0119 0.0128
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Loa Loa (eye worm) latrophilin receptor protein 2 0.0147 0.0783 0.168
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0034 0.0064
Mycobacterium tuberculosis Conserved protein 0.0039 0.0153 0.0472
Schistosoma mansoni tar DNA-binding protein 0.0324 0.1817 0.2019
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0034 0.0045
Loa Loa (eye worm) hypothetical protein 0.0026 0.0077 0.0157
Echinococcus granulosus smad 0.0043 0.0174 0.0189
Loa Loa (eye worm) hypothetical protein 0.004 0.0157 0.0331
Trypanosoma cruzi trypanothione reductase, putative 0.0133 0.0698 0.214
Echinococcus granulosus single minded 2 0.0043 0.0178 0.0194
Echinococcus multilocularis nuclear receptor nhr 48 0.0036 0.0132 0.0128
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0016 0.0018 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0095 0.0196
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0302 0.1689 0.642
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0272 0.1509 0.1506
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0111 0.0107
Brugia malayi Protein kinase domain containing protein 0.0023 0.0057 0.0113
Brugia malayi Protein kinase domain containing protein 0.0023 0.0057 0.0113
Echinococcus multilocularis muscleblind protein 0.0301 0.1683 0.1679
Echinococcus granulosus roundabout 2 0.0016 0.0018 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Schistosoma mansoni inositol monophosphatase 0.0045 0.0185 0.0201
Brugia malayi hypothetical protein 0.0036 0.0132 0.0277
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0075 0.0161
Brugia malayi Pre-SET motif family protein 0.0227 0.125 0.2688
Mycobacterium tuberculosis Probable dehydrogenase 0.0302 0.1689 0.6396
Brugia malayi MH1 domain containing protein 0.0043 0.0174 0.0366
Brugia malayi Muscleblind-like protein 0.0301 0.1683 0.3622
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0075 0.0365 0.0778
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0122 0.0254
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Echinococcus granulosus neuroglian 0.0033 0.0117 0.0126
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0347 0.0343
Loa Loa (eye worm) raf kinase 0.026 0.1443 0.3105
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0068 0.0064
Brugia malayi nuclear hormone receptor 0.0036 0.0132 0.0277
Loa Loa (eye worm) TK protein kinase 0.0045 0.0188 0.0396
Onchocerca volvulus 0.0023 0.0057 0.0103
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.077 0.0853
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0119 0.0369
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0151 0.0261
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0203 0.0198
Schistosoma mansoni hypothetical protein 0.0147 0.0783 0.0867
Onchocerca volvulus 0.0036 0.0132 0.0266
Schistosoma mansoni cell adhesion molecule 0.0016 0.0018 0.0015
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0808 0.4639 0.5163
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0014 0.0017
Schistosoma mansoni adapter molecule crk 0.0025 0.0071 0.0075
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0153 0.0245
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0026 0.0024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0193 0.0624
Echinococcus granulosus survival motor neuron protein 1 0.0493 0.28 0.3115
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0193 0.0572
Schistosoma mansoni aryl hydrocarbon receptor 0.0059 0.0267 0.0293
Onchocerca volvulus 0.0023 0.0057 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0075 0.0365 0.0778
Echinococcus multilocularis N chimaerin 0.0022 0.0052 0.0048
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.069 0.2593
Treponema pallidum NADH oxidase 0.0046 0.0193 0.0319
Brugia malayi nuclear hormone receptor family member nhr-6 0.0036 0.0132 0.0277
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0075 0.0365 0.0361
Brugia malayi MH1 domain containing protein 0.0024 0.0062 0.0126
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0077 0.0213
Plasmodium vivax JmjC domain containing protein 0.0029 0.0095 0.1158
Echinococcus multilocularis mitogen activated protein kinase 0.0065 0.0307 0.0303
Echinococcus granulosus epidermal growth factor receptor 0.0225 0.1239 0.1375
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0036 0.0132 0.0128
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0107 0.0115
Echinococcus multilocularis dna polymerase eta 0.0019 0.0034 0.003
Echinococcus granulosus lachesin 0.0016 0.0018 0.0015
Brugia malayi Protein kinase domain containing protein 0.0023 0.0057 0.0113
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.069 0.1254
Leishmania major DNA polymerase eta, putative 0.0019 0.0034 0.0078
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0465 0.2637 0.568
Echinococcus granulosus peroxidasin 0.0016 0.0018 0.0015
Toxoplasma gondii NAC domain-containing protein 0.0072 0.0344 0.1041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.0365 0.0402
Mycobacterium leprae Probable lipase LipE 0.0039 0.0153 0.0535
Echinococcus multilocularis ecdysone induced protein 78C 0.0075 0.0365 0.0361
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0075 0.0207
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0173 0.0302
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0065 0.0307 0.0925
Plasmodium falciparum importin beta, putative 0.0033 0.0119 0.1604
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0119 0.0342
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0299 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0307 0.0547
Entamoeba histolytica protein kinase, putative 0.0017 0.0025 0.0031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0075 0.0365 0.0361
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0154
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0016 0.0018 0.0013
Echinococcus granulosus FTZ F1 alpha 0.0075 0.0365 0.0402
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0211 0.1154 0.3556
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Brugia malayi MH2 domain containing protein 0.0626 0.3575 0.7705
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0018 0.0027 0.0023
Schistosoma mansoni smad1 5 8 and 0.0043 0.0174 0.0189
Brugia malayi MAP kinase sur-1 0.0065 0.0307 0.0652
Brugia malayi Death domain containing protein 0.0017 0.0026 0.0047
Schistosoma mansoni hypothetical protein 0.0356 0.1998 0.2221
Onchocerca volvulus 0.0017 0.0023 0.0031
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0153 0.0462
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0111 0.023
Schistosoma mansoni inositol monophosphatase 0.0045 0.0185 0.0201
Brugia malayi MH1 domain containing protein 0.0043 0.0174 0.0366
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0157 0.0331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0075 0.0365 0.0778
Loa Loa (eye worm) nuclear receptor NHR-67 0.0036 0.0132 0.0277
Schistosoma mansoni netrin receptor unc5 0.0026 0.0074 0.0078
Schistosoma mansoni septate junction protein 0.0016 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0111 0.023
Schistosoma mansoni DNA helicase recq5 0.0032 0.0111 0.0119
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0808 0.4639 1
Echinococcus granulosus tumor protein p63 0.0368 0.2069 0.23
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0119 0.0128
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0302 0.1689 0.6396
Echinococcus multilocularis tyrosine kinase 0.0023 0.0057 0.0052
Brugia malayi nuclear hormone receptor 0.0075 0.0365 0.0778
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0014 0.0009
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0132 0.1786
Loa Loa (eye worm) hypothetical protein 0.0041 0.0165 0.0347
Loa Loa (eye worm) acetyltransferase 0.0145 0.077 0.1652
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0299 0.1026
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0111 0.0119
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0075 0.0161
Echinococcus multilocularis roundabout 2 0.0016 0.0018 0.0013
Schistosoma mansoni DNA polymerase eta 0.0019 0.0034 0.0033
Leishmania major protein kinase, putative 0.0024 0.0062 0.0166
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.069 0.1481
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0075 0.0123
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0463 0.2623 1
Brugia malayi beta-NAC-like protein 0.0072 0.0344 0.0734
Loa Loa (eye worm) TK/INSR protein kinase 0.0137 0.0724 0.1553
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0347 0.1049
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0016 0.0018 0.0015
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0147 0.0783 0.168
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.0078
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0193 0.021
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0808 0.4639 0.4637
Brugia malayi Nuclear hormone receptor E75 0.0036 0.0132 0.0277
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0075 0.0365 0.0769
Echinococcus granulosus RUN 0.0048 0.0203 0.0221
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0127 0.0265
Echinococcus granulosus mitogen activated protein kinase 14 0.0156 0.0835 0.0925
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0368 0.0364
Echinococcus multilocularis tyrosine protein kinase Fyn 0.007 0.0334 0.033
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.004 0.0157 0.0331
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Schistosoma mansoni tyrosine kinase 0.0259 0.1435 0.1594
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0034 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0034 0.0033
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0151 0.0442
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0299 0.0903
Loa Loa (eye worm) hypothetical protein 0.0031 0.0108 0.0224
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0024
Trichomonas vaginalis set domain proteins, putative 0.0259 0.1433 0.2618
Echinococcus granulosus tyrosine protein kinase Fyn 0.007 0.0334 0.0368
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0153 0.0468
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0068 0.0759
Schistosoma mansoni serine/threonine protein kinase 0.0808 0.4639 0.5163
Echinococcus granulosus NCK adaptor protein 0.0025 0.0071 0.0075
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0153 0.0472
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0018 0.0027 0.0025
Schistosoma mansoni smad1 5 8 and 0.0043 0.0174 0.0189
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0036 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0095 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0075 0.0365 0.0778
Brugia malayi nuclear receptor RXR 0.004 0.0157 0.0331
Brugia malayi beta-lactamase family protein 0.0039 0.0153 0.0322
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0193 0.2592
Brugia malayi Peroxidasin 0.0016 0.0018 0.0029
Schistosoma mansoni lamin 0.0058 0.0266 0.0291
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.069 0.1254
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.069 0.1253
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.0052 0.0054
Brugia malayi 6-phosphofructokinase 0.0131 0.069 0.1481
Schistosoma mansoni nuclear receptor 0.0036 0.0132 0.0143
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0199 0.0349
Schistosoma mansoni tar DNA-binding protein 0.0324 0.1817 0.2019
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.0344 0.4867
Toxoplasma gondii exonuclease III APE 0.0039 0.0153 0.0447
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0151 0.0261
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0014 0.0011
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0193 0.0338
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0193 0.0338
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0368 0.0406
Mycobacterium tuberculosis Probable oxidoreductase 0.0336 0.1886 0.7155
Schistosoma mansoni tyrosine kinase 0.007 0.0334 0.0368
Schistosoma mansoni titin 0.0016 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0095 0.0196
Loa Loa (eye worm) hypothetical protein 0.0175 0.0944 0.2027
Echinococcus multilocularis insulin receptor 0.0137 0.0724 0.072
Loa Loa (eye worm) phosphofructokinase 0.0131 0.069 0.1481
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0034 0.003
Brugia malayi Uncoordinated protein 44 0.0017 0.0026 0.0047
Leishmania major 0.0567 0.3231 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0185 0.8051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0075 0.0365 0.0402
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0075 0.0365 0.0778
Schistosoma mansoni ran 0.0025 0.0068 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0344 0.0616
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0046 0.0193 1
Brugia malayi latrophilin 2 splice variant baaae 0.0318 0.1779 0.3829
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0071
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.002 0.0035
Brugia malayi orphan nuclear receptor NR2E1 0.0036 0.0132 0.0277
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0071
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0068 0.0063
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0129 0.0222
Schistosoma mansoni alpha glucosidase 0.0039 0.0151 0.0164
Echinococcus granulosus tyrosine protein kinase Srms 0.0023 0.0057 0.0058
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.011 0.0315
Echinococcus granulosus importin subunit beta 1 0.0033 0.0119 0.0128
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0075 0.0207
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0036 0.0132 0.0277
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Onchocerca volvulus 0.0023 0.0057 0.0103
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0203 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0075 0.0365 0.0778
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0036 0.007
Brugia malayi hypothetical protein 0.004 0.0157 0.0331
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0301 0.1683 0.3622
Schistosoma mansoni tyrosine kinase 0.0137 0.0724 0.0802
Schistosoma mansoni nck2/grb4 0.0025 0.0071 0.0075
Echinococcus multilocularis neuroglian 0.0033 0.0117 0.0113
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0082 0.0135
Toxoplasma gondii fructose-bisphospatase II 0.0567 0.3231 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0027 0.0025
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.0105
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0153 0.0265
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0018 0.0029
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0095 0.1255
Schistosoma mansoni tyrosine kinase 0.0215 0.1181 0.1311
Entamoeba histolytica hypothetical protein 0.0076 0.0368 0.0662
Echinococcus multilocularis transcription factor btf3 0.0072 0.0344 0.034
Plasmodium vivax importin-beta 2, putative 0.0033 0.0119 0.1511
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.004 0.0157 0.0171
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.069 0.2116
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0153 0.0265
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0089 0.0085
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.069 0.1236
Loa Loa (eye worm) hypothetical protein 0.004 0.0157 0.0331
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0307 0.0653
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0014 0.0009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0511 0.1094
Plasmodium vivax hypothetical protein, conserved 0.0032 0.011 0.1376
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0075 0.0365 0.0402
Brugia malayi Calcitonin receptor-like protein seb-1 0.0465 0.2637 0.568
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0132 0.6582
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0132 0.1695
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0075 0.0161
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.011 0.0315
Schistosoma mansoni tyrosine kinase 0.0023 0.0058 0.0059
Loa Loa (eye worm) hypothetical protein 0.0493 0.28 0.6033
Schistosoma mansoni tar DNA-binding protein 0.0324 0.1817 0.2019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0068 0.0137
Loa Loa (eye worm) hypothetical protein 0.0024 0.0062 0.0126
Loa Loa (eye worm) hypothetical protein 0.004 0.0157 0.0331
Echinococcus multilocularis tyrosine protein kinase Fyn 0.007 0.0334 0.033
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0034 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0014 0.0009
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0036 0.0069
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0151 0.0147
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0182 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1182 0.2157
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0119 0.0128
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0036 0.0035
Echinococcus multilocularis epidermal growth factor receptor 0.0413 0.2332 0.2329
Brugia malayi hypoxia-induced factor 1 0.0182 0.0985 0.2117
Onchocerca volvulus 0.0035 0.0127 0.0255
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Schistosoma mansoni rab6-interacting 0.0048 0.0203 0.0221
Loa Loa (eye worm) hypothetical protein 0.0034 0.012 0.0251
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0463 0.2623 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0075 0.0161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Entamoeba histolytica hypothetical protein 0.0076 0.0368 0.0662
Loa Loa (eye worm) hypothetical protein 0.0465 0.2638 0.5683
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0075 0.0365 0.0778
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0266 0.0565
Schistosoma mansoni cell adhesion molecule 0.0016 0.0018 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0193 0.2673
Echinococcus multilocularis mitogen activated protein kinase 3 0.0065 0.0307 0.0303
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0058 0.0262 0.0258
Onchocerca volvulus 0.0039 0.0153 0.0312
Echinococcus multilocularis peroxidasin 0.0016 0.0018 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0193 0.0572
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0203 0.0198
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0153 0.0462
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0022 0.0052 0.0054
Brugia malayi nuclear receptor RXR 0.0036 0.0132 0.0277
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0082 0.0229
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0048 0.0203 0.0428
Brugia malayi glutathione reductase 0.0133 0.0698 0.1497
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0133 0.0698 0.2574
Echinococcus granulosus Ankyrin 0.0018 0.0027 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0075 0.0365 0.0778
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0036 0.0132 0.0128
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0025 0.0071 0.0075
Mycobacterium ulcerans hypothetical protein 0.0039 0.0153 0.0462
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0336 0.1886 0.7155
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0193 0.0597
Schistosoma mansoni tyrosine kinase 0.0035 0.0129 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1182 0.2157
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0151 0.0261
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.069 0.0686
Echinococcus multilocularis lachesin 0.0016 0.0018 0.0013
Leishmania major trypanothione reductase 0.0133 0.0698 0.214
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.1385 0.5223
Giardia lamblia Fructose-bisphosphate aldolase 0.0947 0.5448 1
Echinococcus granulosus bloom syndrome protein 0.0047 0.0199 0.0217
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0153 0.0265
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0158 0.0488
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0347 0.0381
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0034 0.001
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0014 0.0009
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0193 0.0572
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0027 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0082 0.0135
Loa Loa (eye worm) hypothetical protein 0.0465 0.2638 0.5683
Brugia malayi MH1 domain containing protein 0.0024 0.0062 0.0126
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0347 0.0381
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0329 0.0362
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Schistosoma mansoni nephrin 0.0016 0.0018 0.0015
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0095 0.0101
Schistosoma mansoni vav2 0.0022 0.0052 0.0054
Brugia malayi Protein kinase domain containing protein 0.0808 0.4639 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0153 0.032
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0132 0.6582
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0307 0.0547
Echinococcus multilocularis tyrosine protein kinase Fgr 0.007 0.0334 0.033
Brugia malayi SH2 domain containing protein 0.0023 0.0057 0.0113
Echinococcus granulosus phd:f box containing protein 0.0029 0.0095 0.0101
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0157 0.084 0.1803
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0347 0.1049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0153 0.0447
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0185 0.0323
Echinococcus multilocularis roundabout 2 0.0041 0.0165 0.0161
Mycobacterium ulcerans beta-lactamase 0.0039 0.0153 0.0462
Echinococcus multilocularis c src tyrosine kinase 0.0035 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0049
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Leishmania major hypothetical protein, conserved 0.0026 0.0077 0.0213
Schistosoma mansoni protein kinase 0.0014 0.0009 0.0005
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0478 0.2715 0.3019
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0095 0.0101
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Schistosoma mansoni coup transcription factor 0.0075 0.0365 0.0402
Echinococcus granulosus tyrosine protein kinase Src42A 0.0048 0.0204 0.0223
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0153 0.0166
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0575 0.0635
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.004 0.0157 0.0171
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0035 0.0129 0.0139
Entamoeba histolytica hypothetical protein 0.0076 0.0368 0.0662
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0463 0.2623 1
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.0344 0.1065
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0185 0.0324
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0153 0.0449
Schistosoma mansoni smad 0.0043 0.0174 0.0189
Schistosoma mansoni zinc finger protein 0.0036 0.0132 0.0143
Toxoplasma gondii thioredoxin reductase 0.0133 0.0698 0.214
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0156 0.0835 0.2563
Mycobacterium ulcerans lipase LipD 0.0039 0.0153 0.0462
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0178 0.0559
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Onchocerca volvulus 0.0259 0.1434 0.3077
Leishmania major protein kinase, putative 0.002 0.004 0.0098
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0329 0.114
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0193 0.2673
Brugia malayi hypothetical protein 0.0465 0.2638 0.5683
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0014 0.0009
Echinococcus granulosus roundabout 2 0.0041 0.0165 0.0179
Onchocerca volvulus 0.0026 0.0075 0.0143
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0016 0.0018 0.0013
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0014 0.0009
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0014 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Schistosoma mansoni tyrosine kinase 0.0215 0.1181 0.1311
Toxoplasma gondii fructose-bisphospatase I 0.0211 0.1154 0.3556
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0071
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0185 0.0548
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Schistosoma mansoni blooms syndrome DNA helicase 0.0031 0.0104 0.0112
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0199 0.0421
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0347 0.0622
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0173 0.0511
Leishmania major cytochrome p450-like protein 0.0019 0.0036 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0307 0.0337
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.0944 0.2027
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.004 0.0157 0.0153
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.0944 0.2027
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0225 0.1239 0.1375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Schistosoma mansoni alpha-glucosidase 0.015 0.0802 0.0889
Brugia malayi ecdysone receptor 0.0036 0.0132 0.0277
Onchocerca volvulus 0.0023 0.0057 0.0103
Echinococcus multilocularis peregrin 0.0035 0.0131 0.0126
Echinococcus multilocularis Ankyrin 0.0018 0.0027 0.0023
Schistosoma mansoni fructose-16-bisphosphatase-related 0.0567 0.3231 0.3595
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0169 0.0165
Schistosoma mansoni nephrin 0.0033 0.0117 0.0126
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0058 0.0262 0.0287
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0071 0.0145
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0095 0.0268
Schistosoma mansoni retinoic acid receptor RXR 0.0075 0.0365 0.0402
Brugia malayi Doublecortin family protein 0.0048 0.0203 0.0428
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0344 0.0616
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.004 0.0098
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0036 0.0132 0.0143
Echinococcus granulosus tyrosine protein kinase ABL1 0.0272 0.1509 0.1676
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0077 0.0993
Echinococcus granulosus contactin 0.0016 0.0018 0.0015
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0022 0.0052 0.0104
Schistosoma mansoni inhibitor of apoptosis protein 0.0478 0.2715 0.3019
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0336 0.1886 0.7174
Mycobacterium tuberculosis Conserved protein 0.0039 0.0153 0.0472
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0153 0.0472
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0129 0.04
Onchocerca volvulus 0.0039 0.0153 0.0312
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Echinococcus multilocularis 0.0125 0.0656 0.0652
Brugia malayi Tyrosine-protein kinase abl-1 0.0154 0.0822 0.1765
Loa Loa (eye worm) jmjC domain-containing protein 0.0111 0.0575 0.1231
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.1744 0.3753
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0336 0.1886 0.7155
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0185 0.0181
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0211 0.1154 0.3556
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0022 0.0052 0.0048
Onchocerca volvulus 0.0058 0.0266 0.0555
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0009 0.0026
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0095 0.0091
Brugia malayi protein-tyrosine kinase 0.0058 0.0262 0.0556
Onchocerca volvulus Netrin receptor homolog 0.0025 0.0071 0.0133
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.0344 0.4811
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0095 0.0101
Schistosoma mansoni importin beta-1 0.0033 0.0119 0.0128
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.011 0.0106
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.069 0.2136
Leishmania major basic transcription factor 3a, putative 0.0072 0.0344 0.1041
Trypanosoma brucei protein kinase, putative 0.0014 0.0009 0.0026
Brugia malayi jmjC domain containing protein 0.0029 0.0095 0.0196
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0017 0.0025 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0075 0.0365 0.0402
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.0111 0.0142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0151 0.0261
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0153 0.0472
Mycobacterium ulcerans hypothetical protein 0.0026 0.0075 0.0161
Loa Loa (eye worm) TK protein kinase 0.0058 0.0262 0.0556
Onchocerca volvulus Tyrosine kinase homolog 0.0018 0.0027 0.0039
Echinococcus granulosus GPCR family 2 0.0147 0.0783 0.0867
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0173 0.0511
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0193 0.0597
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0211 0.1154 0.3573
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0153 0.2089
Entamoeba histolytica protein kinase, putative 0.0045 0.0188 0.033
Loa Loa (eye worm) RecQ helicase 0.0047 0.0199 0.0421
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0075 0.0161
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.007 0.0334 0.033
Schistosoma mansoni cell adhesion molecule 0.0034 0.012 0.0129
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0075 0.0365 0.0402
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.002 0.0044 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.069 0.0764
Brugia malayi phosphofructokinase 0.0131 0.069 0.1481
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0034 0.0064
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0153 0.0148
Brugia malayi Protein kinase domain containing protein 0.0504 0.2862 0.6165
Loa Loa (eye worm) hypothetical protein 0.0025 0.0071 0.0145
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0153 0.0472
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0027 0.0049
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0068 0.021
Onchocerca volvulus 0.0058 0.0266 0.0555
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0153 0.0166
Echinococcus multilocularis lamin dm0 0.0058 0.0266 0.0262
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0075 0.0365 0.0402
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0154
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0147 0.0783 0.0779
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0329 0.1149
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0025 0.0068 0.0184
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0043 0.0178 0.0375
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0075 0.0154
Echinococcus multilocularis tyrosine protein kinase HCK 0.0045 0.0188 0.0184
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0132 0.0128
Trichomonas vaginalis esterase, putative 0.0039 0.0153 0.0265
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0075 0.0161
Echinococcus granulosus mitogen activated protein kinase 0.0065 0.0307 0.0337
Echinococcus multilocularis tyrosine protein kinase otk 0.0016 0.0018 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0075 0.0365 0.0778
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0153 0.0472
Giardia lamblia Kinase, CMGC MAPK 0.0065 0.0307 0.0504
Trypanosoma brucei trypanothione reductase 0.0133 0.0698 0.2161
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0075 0.0365 0.0402
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0174 0.0366
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0014 0.0017
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0302 0.0642
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0075 0.0365 0.0402
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.069 0.0764
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0034 0.012 0.0129
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0185 0.0548
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0209 0.1144 0.1141
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0151 0.0261
Schistosoma mansoni hypothetical protein 0.0318 0.1779 0.1976
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0075 0.0365 0.0361
Schistosoma mansoni hypothetical protein 0.0478 0.2715 0.3019
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0036 0.0087
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0065 0.0307 0.0925
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0153 0.0264
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0443 0.0489
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0071 0.0145
Echinococcus granulosus inhibitor of apoptosis protein 0.0478 0.2715 0.3019
Trypanosoma brucei glucosidase, putative 0.0039 0.0151 0.0467
Schistosoma mansoni smad1 5 8 and 0.0043 0.0174 0.0189
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.0105
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0057 0.0088
Brugia malayi hypothetical protein 0.0197 0.1074 0.2309
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0111 0.1484
Loa Loa (eye worm) hypoxia-induced factor 1 0.0182 0.0985 0.2117
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0095 0.0294
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0151 0.0261
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0071
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0014 0.0011
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0153 0.0219
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0068 0.086
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0193 0.0572
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.007 0.0334 0.033
Echinococcus multilocularis muscleblind protein 1 0.0301 0.1683 0.1679
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0075 0.0365 0.0778
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0132 0.0226
Echinococcus granulosus lamin 0.0058 0.0266 0.0291
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0065 0.0307 0.0949
Echinococcus multilocularis Polycystic kidney disease protein 0.0048 0.0203 0.0198
Echinococcus multilocularis musashi 0.0058 0.0266 0.0262
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0034 0.0033
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0089 0.0095
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0248
Echinococcus granulosus intermediate filament protein 0.0058 0.0266 0.0291
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.004 0.0098
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.0118
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0153 0.0165
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0153 0.0265
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0153 0.0166
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0153 0.0459
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0174 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0151 0.0442
Echinococcus multilocularis lamin 0.0058 0.0266 0.0262
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1037 0.1034
Trypanosoma brucei unspecified product 0.0019 0.0034 0.0105
Echinococcus multilocularis smad 0.0043 0.0174 0.0169
Echinococcus multilocularis Protein lozenge 0.0058 0.0265 0.0261
Schistosoma mansoni thyroid hormone receptor 0.0075 0.0365 0.0402
Echinococcus multilocularis activin receptor type 0.0014 0.0009 0.0004
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0034 0.0105
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0344 0.1041
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Schistosoma mansoni neuroglian 0.0016 0.0018 0.0015
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0137 0.0724 0.072
Entamoeba histolytica recQ family DNA helicase 0.0016 0.002 0.002
Echinococcus granulosus fructose 16 bisphosphatase 1 0.0567 0.3231 0.3595
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0095 0.0101
Schistosoma mansoni septate junction protein 0.0016 0.0018 0.0015
Onchocerca volvulus 0.0101 0.0511 0.1085
Schistosoma mansoni tyrosine kinase 0.0035 0.0129 0.0139
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0132 0.1695
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0075 0.0365 0.0402
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0151 0.0261
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0111 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0504 0.2862 0.6165
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0329 0.114
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0567 0.3231 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1037 0.1151
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0153 0.0265
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0209 0.1144 0.127
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0119 0.0115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Echinococcus granulosus tyrosine protein kinase otk 0.0016 0.0018 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0193 0.0614
Echinococcus multilocularis microtubule associated protein 2 0.1553 0.8982 0.8981
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0095 0.0101
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0034 0.0033
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0095 0.0268
Echinococcus multilocularis GPCR, family 2 0.0147 0.0783 0.0779
Schistosoma mansoni serine/threonine protein kinase 0.027 0.1501 0.1667
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0075 0.0365 0.0778
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0174 0.0189
Schistosoma mansoni hypothetical protein 0.002 0.0043 0.0043
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.002 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0075 0.0365 0.0778
Echinococcus multilocularis tyrosine protein kinase Src64B 0.007 0.0334 0.033
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0185 0.0201
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0153 0.2089
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0014 0.0009 0.0004
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0478 0.2715 0.2712
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.1744 0.3753
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0036 0.0035
Entamoeba histolytica Ran family GTPase 0.0025 0.0068 0.0109
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0299 0.0903
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0075 0.0365 0.0402
Schistosoma mansoni tyrosine kinase 0.0225 0.1239 0.1375
Brugia malayi Raf kinase 0.0261 0.1448 0.3114
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0037 0.0311
Echinococcus granulosus tar DNA binding protein 0.0324 0.1817 0.2019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0034 0.0078
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0016 0.0018 0.0013
Echinococcus granulosus lamin dm0 0.0058 0.0266 0.0291
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0075 0.017
Schistosoma mansoni protein kinase 0.0014 0.0009 0.0005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0065 0.0307 0.0925
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0095 0.0101
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0071 0.0145
Echinococcus granulosus tyrosine protein kinase shark 0.0023 0.0058 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0746 0.0826
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0211 0.1154 0.3556
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Schistosoma mansoni tyrosine kinase 0.0225 0.1239 0.1375
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0185 0.0548
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.069 0.2536
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0034 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0034 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0228
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0182 0.0178
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1037 0.1151
Loa Loa (eye worm) ICD-1 protein 0.0072 0.0344 0.0734
Echinococcus multilocularis tyrosine protein kinase Srms 0.0058 0.0262 0.0258
Echinococcus multilocularis netrin receptor unc 5 0.0026 0.0074 0.007
Echinococcus granulosus neuroglian 0.0016 0.0018 0.0015
Echinococcus granulosus thyroid hormone receptor alpha 0.0036 0.0132 0.0143
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0036 0.0132 0.0143
Echinococcus multilocularis snurportin 1 0.0356 0.1998 0.1995
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0054 0.0108
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.1037 0.2229
Schistosoma mansoni tar DNA-binding protein 0.0324 0.1817 0.2019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0347 0.1049
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0151 0.0317
Plasmodium falciparum glutathione reductase 0.0133 0.0698 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0151 0.0442
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0575 0.0635
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0065 0.0307 0.0652
Echinococcus granulosus twitchin 0.0037 0.0143 0.0155
Schistosoma mansoni lamin 0.0058 0.0266 0.0291
Echinococcus multilocularis tyrosine protein kinase Abl 0.013 0.0684 0.0681
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0065 0.0307 0.0925
Leishmania major hypothetical protein, conserved 0.0029 0.0095 0.0268
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0095 0.0091
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0808 0.4639 1
Schistosoma mansoni hypothetical protein 0.0147 0.0783 0.0867
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0077 0.0993
Echinococcus multilocularis tumor protein p63 0.0368 0.2069 0.2066
Schistosoma mansoni cell adhesion molecule 0.0016 0.0018 0.0015
Echinococcus granulosus tyrosine kinase 0.0023 0.0057 0.0058
Echinococcus granulosus dna polymerase kappa 0.0019 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Echinococcus multilocularis mitogen activated protein kinase 14 0.0156 0.0835 0.0831
Brugia malayi CXXC zinc finger family protein 0.0035 0.0127 0.0265
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0037 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0036 0.0132 0.0143
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0095 0.0101
Loa Loa (eye worm) beta-lactamase 0.0039 0.0153 0.0322
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0111 0.0107
Echinococcus granulosus tyrosine protein kinase Src42A 0.007 0.0334 0.0368
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Schistosoma mansoni hypothetical protein 0.0147 0.0783 0.0867
Entamoeba histolytica hypothetical protein 0.0027 0.0082 0.0136
Brugia malayi hypothetical protein 0.0048 0.0203 0.0428
Echinococcus multilocularis NCK adaptor protein 0.0025 0.0071 0.0067
Onchocerca volvulus 0.0036 0.0132 0.0266
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0174 0.0189
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0137 0.0724 0.0802
Echinococcus granulosus nuclear receptor nhr 48 0.0036 0.0132 0.0143
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0075 0.0365 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0014 0.0009
Schistosoma mansoni roundabout 0.0016 0.0018 0.0015
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0119 0.0128
Brugia malayi jmjC domain containing protein 0.0029 0.0095 0.0196
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.007 0.0334 0.0368
Loa Loa (eye worm) MH2 domain-containing protein 0.0626 0.3575 0.7705
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0132 0.0181
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0329 0.0701
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0567 0.3231 1
Brugia malayi RNA binding protein 0.0324 0.1817 0.3912
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0947 0.5448 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0947 0.5448 1
Schistosoma mansoni ap endonuclease 0.0039 0.0153 0.0165
Echinococcus multilocularis neuroglian 0.0016 0.0018 0.0013
Plasmodium vivax SET domain protein, putative 0.0033 0.0119 0.1506
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0095 0.0101
Schistosoma mansoni tyrosine kinase 0.007 0.0334 0.0368
Schistosoma mansoni tyrosine kinase 0.0023 0.0057 0.0058
Brugia malayi jmjC domain containing protein 0.0029 0.0095 0.0196
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0129 0.0374
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0044 0.0181 0.2499
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0193 0.0189
Echinococcus multilocularis inhibitor of apoptosis protein 0.0478 0.2715 0.2712
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.002 0.004 0.0098
Schistosoma mansoni Smad4 0.0019 0.0036 0.0035
Onchocerca volvulus 0.0478 0.2715 0.5844
Schistosoma mansoni hypothetical protein 0.0147 0.0783 0.0867
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0026 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1037 0.1151
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0111 0.023
Brugia malayi Latrophilin receptor protein 2 0.0147 0.0783 0.168
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0153 0.0447
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0075 0.0235
Brugia malayi hypothetical protein 0.0023 0.0057 0.0113
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0174 0.0366
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0065 0.0307 0.0925
Echinococcus multilocularis geminin 0.0353 0.1986 0.1983
Loa Loa (eye worm) hypothetical protein 0.0478 0.2715 0.5848
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0153 0.032
Echinococcus multilocularis hemicentin 1 0.0016 0.0018 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0075 0.0365 0.0402
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0193 0.0572
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0151 0.0442
Onchocerca volvulus Alhambra homolog 0.0032 0.011 0.0218
Treponema pallidum fructose-bisphosphate aldolase 0.0947 0.5448 1
Schistosoma mansoni hypothetical protein 0.0076 0.0368 0.0406
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Brugia malayi hypothetical protein 0.0493 0.28 0.6033
Onchocerca volvulus Bile acid receptor homolog 0.0075 0.0365 0.0769
Schistosoma mansoni loxhd1 0.0048 0.0203 0.0221
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0193 0.0597
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0153 0.0265
Onchocerca volvulus 0.0048 0.0203 0.0418
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0153 0.0322
Brugia malayi ecdysteroid receptor 0.0075 0.0365 0.0778
Schistosoma mansoni smad 0.0019 0.0036 0.0035
Echinococcus multilocularis tyrosine protein kinase Blk 0.0058 0.0262 0.0258
Echinococcus multilocularis tyrosine protein kinase Src42A 0.007 0.0334 0.033
Mycobacterium tuberculosis Probable reductase 0.0302 0.1689 0.6396
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0037 0.1308
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.002 0.004 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0322
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Echinococcus granulosus roundabout 2 0.0016 0.0018 0.0015
Loa Loa (eye worm) thioredoxin reductase 0.0133 0.0698 0.1497
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.069 0.2544
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0153 0.0472
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0026 0.0024
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0347 0.0739
Schistosoma mansoni tar DNA-binding protein 0.0324 0.1817 0.2019
Plasmodium falciparum phd finger protein, putative 0.0032 0.011 0.147
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0344 0.0616
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0302 0.1689 0.6396
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.002 0.0035
Echinococcus multilocularis tar DNA binding protein 0.0324 0.1817 0.1814
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0443 0.0439
Echinococcus granulosus tyrosine protein kinase Src64B 0.007 0.0334 0.0368
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0153 0.0535
Schistosoma mansoni single-minded 0.0059 0.0267 0.0293
Echinococcus multilocularis hemicentin 1 0.0016 0.0018 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0075 0.0365 0.0778
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0036 0.0132 0.0277
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0156 0.0835 0.2583
Loa Loa (eye worm) glutathione reductase 0.0133 0.0698 0.1497
Schistosoma mansoni lipoxygenase 0.0123 0.0644 0.0713
Plasmodium vivax multidomain scavenger receptor, putative 0.0048 0.0203 0.2735
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0068 0.0071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0075 0.0123
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0036 0.001
Brugia malayi hypothetical protein 0.0017 0.0023 0.0041
Loa Loa (eye worm) transcription factor SMAD2 0.0626 0.3575 0.7705
Brugia malayi Sex muscle abnormal protein 5 0.0025 0.0071 0.0145
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0156 0.0835 0.2563
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0111 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0075 0.0365 0.0778
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0193 0.0614
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0119 0.0343
Trichomonas vaginalis ran, putative 0.0025 0.0068 0.0108
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0185 0.0584
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0299 0.1026
Mycobacterium tuberculosis Conserved protein 0.0039 0.0153 0.0472
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0147 0.0783 0.0779
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0153 0.2001
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0178 0.0376
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0075 0.0154
Echinococcus granulosus tyrosine protein kinase Blk 0.0058 0.0262 0.0287
Brugia malayi jmjC domain containing protein 0.0111 0.0575 0.1231
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0193 0.0614
Brugia malayi hypothetical protein 0.0076 0.0368 0.0786
Brugia malayi photoreceptor-specific nuclear receptor 0.0075 0.0365 0.0778
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Brugia malayi conserved hypotetical protein 0.0036 0.0132 0.0277
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0153 0.0472
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0478 0.2715 0.3019
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0018 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0077 0.0213
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0153 0.0322
Echinococcus granulosus Immunoglobulin 0.0025 0.0072 0.0076
Plasmodium falciparum thioredoxin reductase 0.0046 0.0193 0.2673
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0299 0.1026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Echinococcus granulosus peregrin 0.0035 0.0131 0.0141
Entamoeba histolytica hypothetical protein 0.0076 0.0368 0.0662
Echinococcus granulosus tyrosine protein kinase Lyn 0.0075 0.036 0.0397
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.011 0.0118
Loa Loa (eye worm) hypothetical protein 0.0073 0.0353 0.0752
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0478 0.2715 0.5848
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0016 0.0018 0.0018
Schistosoma mansoni lipoxygenase 0.0209 0.1144 0.127
Leishmania major DNA polymerase kappa, putative 0.0019 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0318 0.1779 0.3829
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.069 0.1253
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0307 0.0547
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0169 0.0184
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.077 0.0766
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.069 0.1253
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.0052 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.0365 0.0361
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0036 0.0058
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0147 0.0783 0.0867
Brugia malayi jmjC domain containing protein 0.0029 0.0095 0.0196
Echinococcus multilocularis lysine specific demethylase 5A 0.0109 0.0563 0.0559
Loa Loa (eye worm) TK/ABL protein kinase 0.0272 0.1509 0.3247
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.0365 0.0402
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0016 0.0018 0.0015
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0203 0.0221
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Brugia malayi Pre-SET motif family protein 0.0033 0.0119 0.0247
Brugia malayi Importin beta-1 subunit 0.0033 0.0119 0.0248
Loa Loa (eye worm) hypothetical protein 0.0105 0.0538 0.1151
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.2805 0.2802
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0153 0.0219
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0075 0.0154
Onchocerca volvulus 0.0054 0.0239 0.0496
Echinococcus multilocularis Immunoglobulin 0.0025 0.0072 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0075 0.0365 0.0778
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0174 0.0169
Brugia malayi MH2 domain containing protein 0.0043 0.0174 0.0366
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0086 0.0241
Brugia malayi 6-phosphofructokinase 0.0131 0.069 0.1481
Brugia malayi Furin-like cysteine rich region family protein 0.0413 0.2332 0.5023
Schistosoma mansoni ap endonuclease 0.0039 0.0153 0.0165
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0009 0.0028
Brugia malayi Prion-like- 0.0016 0.0018 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.007 0.0334 0.033
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0065 0.0307 0.0925
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0037 0.0417
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Echinococcus multilocularis survival motor neuron protein 1 0.0493 0.28 0.2797
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0193 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0014 0.001
Brugia malayi MH2 domain containing protein 0.0019 0.0036 0.0069
Leishmania major GTP-binding protein, putative 0.0025 0.0068 0.0184
Onchocerca volvulus 0.0465 0.2638 0.5679
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0074 0.0151
Brugia malayi Protein kinase domain containing protein 0.0137 0.0724 0.1553
Loa Loa (eye worm) RNA binding protein 0.0324 0.1817 0.3912
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0108 0.0223
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0132 0.0206
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0095 0.0196
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0014 0.0021
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0068 0.0184
Brugia malayi Inositol-1 0.0045 0.0185 0.039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.0344 0.0617
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0095 0.0196
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0119 0.0115
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0075 0.0161
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0156 0.0835 0.1792
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0068 0.0137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Plasmodium falciparum glutathione reductase 0.0046 0.0193 0.2673
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0185 0.0323
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0153 0.0265
Entamoeba histolytica recQ family helicase, putative 0.0016 0.0016 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0057 0.0113
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0808 0.4639 1
Schistosoma mansoni lozenge 0.0058 0.0265 0.0291
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0158 0.0551
Brugia malayi beta-lactamase 0.0039 0.0153 0.0322
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0157 0.0171
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0119 0.0369
Echinococcus multilocularis FTZ F1 alpha 0.0075 0.0365 0.0361
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0132 0.0382
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0157 0.0331
Loa Loa (eye worm) doublecortin family protein 0.0048 0.0203 0.0428
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0075 0.0365 0.0402
Brugia malayi hypothetical protein 0.0025 0.0072 0.0147
Echinococcus multilocularis roundabout 2 0.0016 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0302 0.1689 0.6396
Echinococcus granulosus netrin receptor unc 5 0.0026 0.0074 0.0078
Entamoeba histolytica hypothetical protein 0.0072 0.0344 0.0617
Echinococcus granulosus Smad4 0.0043 0.0174 0.0189
Schistosoma mansoni alpha-glucosidase 0.015 0.0802 0.0889
Echinococcus multilocularis cpg binding protein 0.0037 0.0139 0.0135
Echinococcus granulosus mitogen activated protein kinase 11 0.0156 0.0835 0.0925
Brugia malayi Protein kinase domain containing protein 0.0023 0.0057 0.0113
Trypanosoma brucei fructose-1,6-bisphosphatase 0.0567 0.3231 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0075 0.0365 0.0778
Brugia malayi MH2 domain containing protein 0.0043 0.0174 0.0366
Schistosoma mansoni vesicular amine transporter 0.0025 0.0072 0.0076
Echinococcus granulosus lysine specific demethylase 5A 0.0111 0.0575 0.0635
Brugia malayi RNA, U transporter 1 0.0095 0.0477 0.1021
Echinococcus multilocularis thioredoxin glutathione reductase 0.0134 0.0704 0.07
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Echinococcus multilocularis RUN 0.0048 0.0203 0.0198
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.007 0.0334 0.0368
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.0944 0.1047
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0175 0.0945 0.1048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0043 0.0043
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0336 0.1015
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0068 0.0184
Echinococcus multilocularis mitogen activated protein kinase 14 0.0156 0.0835 0.0831
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0021
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0347 0.1073
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.017
Loa Loa (eye worm) hypothetical protein 0.0301 0.1683 0.3622
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0119 0.0128
Echinococcus granulosus geminin 0.0353 0.1986 0.2208
Brugia malayi Fibronectin type III domain containing protein 0.0025 0.0072 0.0147
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.069 0.0764
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0023 0.0057 0.0052
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0025 0.0072 0.0076
Brugia malayi nuclear receptor NHR-88 0.0036 0.0132 0.0277
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Brugia malayi Immunoglobulin I-set domain containing protein 0.0043 0.0178 0.0375
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0129 0.0221
Loa Loa (eye worm) Smad1 0.0043 0.0174 0.0366
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0193 0.0597
Brugia malayi tailless protein 0.0036 0.0132 0.0277
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0178 0.0174
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0151 0.0262
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0193 0.0407
Onchocerca volvulus 0.0023 0.0057 0.0103
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.009 0.1079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0035 0.0129 0.0139
Loa Loa (eye worm) hypothetical protein 0.0075 0.0365 0.0778
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0132 0.0143
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.077 0.1652
Onchocerca volvulus 0.0048 0.0203 0.0418
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.069 0.1253
Echinococcus granulosus mitogen activated protein kinase 3 0.0065 0.0307 0.0337
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.002 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0036 0.007
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0193 0.021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.069 0.1481
Schistosoma mansoni Smad4 0.0019 0.0036 0.0035
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.051 0.2898 0.3224
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0199 0.0349
Echinococcus multilocularis raf serine:threonine protein kinase 0.027 0.1501 0.1497
Brugia malayi steroid hormone receptor 0.0075 0.0365 0.0778
Brugia malayi fructose-1,6-bisphosphatase 0.0567 0.3231 0.6963
Schistosoma mansoni hypothetical protein 0.0353 0.1986 0.2208
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0009 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0036 0.0132 0.0266
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0111 0.0318
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0465 0.2637 0.568
Schistosoma mansoni cpg binding protein 0.0035 0.0127 0.0137
Brugia malayi Cytochrome P450 family protein 0.0019 0.0036 0.007
Brugia malayi nuclear receptor NHR-67 0.0036 0.0132 0.0277
Schistosoma mansoni transcription factor btf3 0.0072 0.0344 0.0379
Echinococcus granulosus dna polymerase eta 0.0019 0.0034 0.0033
Schistosoma mansoni tyrosine kinase 0.0026 0.0075 0.0079
Brugia malayi beta-lactamase family protein 0.0039 0.0153 0.0322
Loa Loa (eye worm) runx1 0.0058 0.0265 0.0563
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0266 0.0565
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0108 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0075 0.0365 0.0778
Echinococcus granulosus insulin receptor 0.0137 0.0724 0.0802
Brugia malayi SH2 domain containing protein 0.0023 0.0057 0.0113
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.0365 0.0361
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0075 0.0207
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0119 0.0115
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0077 0.0238
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0329 0.0994
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0075 0.0365 0.0402
Echinococcus granulosus tyrosine kinase 0.0058 0.0262 0.0287
Trypanosoma brucei protein kinase, putative 0.0065 0.0307 0.0949
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0173 0.0302
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Loa Loa (eye worm) hypothetical protein 0.0465 0.2637 0.568
Echinococcus granulosus epidermal growth factor receptor 0.0413 0.2332 0.2593
Schistosoma mansoni tyrosine kinase 0.0137 0.0724 0.0802
Schistosoma mansoni ran 0.0025 0.0068 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0069
Schistosoma mansoni cpg binding protein 0.0037 0.0139 0.015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0153 0.0447
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0299 0.0329
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0153 0.2013
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0111 0.023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0014 0.0017
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0153 0.0149
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0299 0.0329
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0193 0.0572
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0035 0.0129 0.0125
Brugia malayi Smad1 0.0043 0.0174 0.0366
Loa Loa (eye worm) inositol-1 0.0045 0.0185 0.039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0036 0.0132 0.0128
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0174 0.0169
Schistosoma mansoni hypothetical protein 0.0048 0.0203 0.0221
Loa Loa (eye worm) DR-78 0.0036 0.0132 0.0277
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0478 0.2715 0.5848
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0329 0.0325
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0147 0.0783 0.0867
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0266 0.0565
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0023 0.0057 0.0058
Echinococcus multilocularis epidermal growth factor receptor 0.0225 0.1239 0.1235
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0009 0.0011
Toxoplasma gondii ABC1 family protein 0.0039 0.0153 0.0449
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0025 0.0072 0.0068
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0048 0.0204 0.02
Loa Loa (eye worm) nuclear factor I 0.0024 0.0062 0.0126
Loa Loa (eye worm) nuclear hormone receptor 0.0036 0.0132 0.0277
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0132 0.0382
Loa Loa (eye worm) hypothetical protein 0.0054 0.0239 0.0506
Echinococcus granulosus activin receptor type 0.0014 0.0009 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0075 0.0365 0.0769
Schistosoma mansoni DNA helicase recq1 0.0032 0.0111 0.0119
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0071 0.0075
Schistosoma mansoni Smad4 0.0043 0.0174 0.0189
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0132 0.0143
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0036 0.0113
Brugia malayi SRC-1 0.007 0.0334 0.0712
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0329 0.0362
Schistosoma mansoni jumonji domain containing protein 0.0154 0.0821 0.0909
Echinococcus granulosus N chimaerin 0.0022 0.0052 0.0054
Schistosoma mansoni nuclear receptor nhr-48 0.0036 0.0132 0.0143
Brugia malayi Nuclear hormone receptor-like 1 0.0075 0.0365 0.0778
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Echinococcus multilocularis mitogen activated protein kinase 11 0.0156 0.0835 0.0831
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0077 0.0894
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0075 0.017
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0009 0.0001
Brugia malayi nuclear receptor NHR-88 0.0075 0.0365 0.0778
Brugia malayi nuclear hormone receptor family member odr-7 0.0036 0.0132 0.0277
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0071 0.0075
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0122 0.0254
Schistosoma mansoni protein kinase 0.0014 0.0009 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0075 0.0123
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0082 0.0135
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.0567 0.3231 0.3228
Plasmodium falciparum thioredoxin reductase 0.0133 0.0698 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0356 0.1998 0.4303
Brugia malayi PAS domain containing protein 0.0059 0.0267 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0089 0.0184
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0185 0.0548
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.0567 0.3231 0.6963
Echinococcus granulosus tyrosine protein kinase Fyn 0.007 0.0334 0.0368
Echinococcus granulosus transcription factor btf3 0.0072 0.0344 0.0379
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0132 0.1786
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0299 0.0295
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0064
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.1037 0.1151
Brugia malayi Protein kinase domain containing protein 0.0022 0.0052 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0944 0.094
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0153 0.0449
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0193 0.0572
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0025 0.0072 0.0076
Onchocerca volvulus 0.0033 0.0119 0.0237
Schistosoma mansoni tyrosine kinase 0.0413 0.2332 0.2593
Brugia malayi P38 map kinase family protein 2 0.0156 0.0835 0.1792
Onchocerca volvulus 0.0023 0.0057 0.0103
Brugia malayi N-terminal motif family protein 0.0175 0.0944 0.2027
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.007 0.0334 0.033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.1037 0.1151
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0132 0.0143
Echinococcus multilocularis growth factor receptor bound protein 2 0.0025 0.0071 0.0067
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0036 0.0032
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0129 0.0374
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Loa Loa (eye worm) hypothetical protein 0.0023 0.0057 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0072 0.0147
Loa Loa (eye worm) hypothetical protein 0.0057 0.026 0.0551
Plasmodium vivax thioredoxin reductase, putative 0.0133 0.0698 1
Echinococcus granulosus defective proboscis extension response 0.0025 0.0072 0.0076
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0147
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.0684 0.1468
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.125 0.2688
Leishmania major importin beta-1 subunit, putative 0.0027 0.0082 0.0229
Echinococcus multilocularis Smad4 0.0043 0.0174 0.0169
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0361 0.0397
Brugia malayi PHD-finger family protein 0.0032 0.011 0.0228
Loa Loa (eye worm) TAR-binding protein 0.0324 0.1817 0.3912
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Loa Loa (eye worm) hypothetical protein 0.0058 0.0266 0.0565
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0095 0.0268
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0151 0.0164
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0368 0.0406
Brugia malayi Nuclear hormone receptor E75 0.0036 0.0132 0.0277
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0036 0.0069
Brugia malayi TAR-binding protein 0.0324 0.1817 0.3912
Loa Loa (eye worm) hypothetical protein 0.0147 0.0783 0.168
Schistosoma mansoni nuclear hormone receptor 0.0075 0.0365 0.0402
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0153 0.0472
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0344 0.1041
Brugia malayi intermediate filament protein 0.0058 0.0266 0.0565
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0185 0.0323
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.069 0.1254
Plasmodium vivax glutathione reductase, putative 0.0133 0.0698 1
Schistosoma mansoni cpg binding protein 0.0037 0.0139 0.015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0299 0.1035
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0014 0.0009 0.0005
Echinococcus multilocularis Immunoglobulin 0.0025 0.0072 0.0068
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0034 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0075 0.0365 0.0778
Brugia malayi RhoGAP domain containing protein 0.0022 0.0052 0.0104
Brugia malayi Steroid receptor seven-up type 2 0.0075 0.0365 0.0778
Schistosoma mansoni tyrosine kinase 0.0215 0.1181 0.1311
Schistosoma mansoni RAR-like nuclear receptor 0.0075 0.0365 0.0402
Loa Loa (eye worm) hypothetical protein 0.0197 0.1074 0.2309
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.004 0.0157 0.0331
Brugia malayi hypothetical protein 0.0048 0.0203 0.0428
Loa Loa (eye worm) hypothetical protein 0.0478 0.2715 0.5848
Brugia malayi hypothetical protein 0.0036 0.0132 0.0277
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0173 0.0188
Loa Loa (eye worm) hypothetical protein 0.0029 0.0095 0.0196
Loa Loa (eye worm) hypothetical protein 0.004 0.0157 0.0331
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0036 0.007
Echinococcus granulosus tyrosine protein kinase HCK 0.0045 0.0188 0.0204
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0193 0.0572
Echinococcus granulosus death domain containing protein 0.0017 0.0026 0.0024
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0107 0.0114
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0052 0.0104
Schistosoma mansoni hypothetical protein 0.0494 0.2805 0.312
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0077 0.0213
Echinococcus granulosus c src tyrosine kinase 0.0035 0.0129 0.0139
Echinococcus granulosus ecdysone induced protein 78C 0.0075 0.0365 0.0402
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0034 0.0046
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0185 0.0573
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0151 0.0317
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0026 0.0022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0302 0.1689 0.6396
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0193 0.2592
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.1118 0.2396
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0307 0.0547
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0203 0.0221
Brugia malayi Thioredoxin reductase 0.0133 0.0698 0.1497
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0151 0.0261
Loa Loa (eye worm) TK protein kinase 0.0018 0.0027 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Echinococcus granulosus dnaJ subfamily B 0.0494 0.2805 0.312
Brugia malayi Bromodomain containing protein 0.0035 0.0131 0.0273
Schistosoma mansoni rab6-interacting 0.0048 0.0203 0.0221
Onchocerca volvulus 0.0039 0.0153 0.0312
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0153 0.0475
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Brugia malayi RNA recognition motif domain containing protein 0.0324 0.1817 0.3912
Brugia malayi hypothetical protein 0.004 0.0157 0.0331
Schistosoma mansoni microtubule-associated protein tau 0.1553 0.8982 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0036 0.0132 0.0143
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0095 0.0268
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0173 0.2305
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0151 0.0261
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0037 0.0024
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0014 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0036 0.0132 0.0143
Brugia malayi jmjC domain containing protein 0.0175 0.0945 0.203
Echinococcus multilocularis thyroid hormone receptor alpha 0.0075 0.0365 0.0361
Echinococcus granulosus hemicentin 1 0.0016 0.0018 0.0015
Onchocerca volvulus 0.0015 0.0014 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0075 0.0365 0.0361
Schistosoma mansoni steroid hormone receptor ad4bp 0.0075 0.0365 0.0402
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0065 0.0307 0.0925
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0153 0.0264
Echinococcus multilocularis mitogen activated protein kinase 11 0.0156 0.0835 0.0831
Loa Loa (eye worm) TK/EGFR protein kinase 0.0413 0.2332 0.5023
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.1037 0.2229
Onchocerca volvulus 0.0043 0.0178 0.0366
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0132 0.0382
Echinococcus granulosus thioredoxin glutathione reductase 0.0134 0.0704 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0055 0.0056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0018 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0075 0.0365 0.0778
Brugia malayi hypothetical protein 0.0026 0.0077 0.0157
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0193 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0075 0.0365 0.0778
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0199 0.0195
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1118 0.2039
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0036 0.0132 0.0128
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0944 0.094
Onchocerca volvulus 0.0075 0.0365 0.0769
Echinococcus multilocularis tyrosine protein kinase shark 0.0023 0.0058 0.0053
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.011 0.0118
Schistosoma mansoni hypothetical protein 0.0101 0.0511 0.0565
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.069 0.2116
Loa Loa (eye worm) hypothetical protein 0.0041 0.0165 0.0347
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0036 0.0069
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0132 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0151 0.0262
Echinococcus granulosus Polycystic kidney disease protein 0.0048 0.0203 0.0221
Echinococcus granulosus tyrosine protein kinase Fyn 0.007 0.0334 0.0368
Giardia lamblia PHD finger protein 15 0.0032 0.011 0.0141
Echinococcus granulosus muscleblind protein 0.0301 0.1683 0.187
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0034 0.0105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.1037 0.1034
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0132 0.0225
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0324 0.1817 0.3912
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0075 0.0235
Echinococcus granulosus cpg binding protein 0.0037 0.0139 0.015
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0156 0.0835 0.2563
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0175 0.0945 0.0941
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0347 0.0739
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0009 0.0002
Echinococcus granulosus growth factor receptor bound protein 2 0.0025 0.0071 0.0075
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.011 0.0228
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0808 0.4639 1
Plasmodium falciparum LCCL domain-containing protein 0.0048 0.0203 0.2814
Onchocerca volvulus Deterin homolog 0.0478 0.2715 0.5844
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0025 0.0071 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1744 0.3189
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0193 1
Brugia malayi Cytochrome P450 family protein 0.0019 0.0036 0.007
Leishmania major hypothetical protein, conserved 0.0039 0.0153 0.0449
Schistosoma mansoni intermediate filament proteins 0.0058 0.0266 0.0291
Schistosoma mansoni nuclear receptor 0.0036 0.0132 0.0143
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.0944 0.2019
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0014 0.0009
Schistosoma mansoni survival motor neuron protein 0.0101 0.0511 0.0565
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0239 0.0261
Echinococcus granulosus snurportin 1 0.0356 0.1998 0.2221
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0036 0.0132 0.0266
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0029
Loa Loa (eye worm) SRC-1 0.007 0.0334 0.0712
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0277
Echinococcus granulosus raf serine:threonine protein kinase 0.027 0.1501 0.1667
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0247
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0016 0.0018 0.0013
Echinococcus granulosus microtubule associated protein 2 0.1553 0.8982 1
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0036 0.0087
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0947 0.5448 1
Brugia malayi Protein kinase domain containing protein 0.0023 0.0057 0.0113

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.1 uM Antagonism towards Epidermal growth factor receptor ChEMBL. No reference
IC50 (functional) = 1.5 uM Antagonism towards Colony stimulating factor 1 receptor (CSF-1R) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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