Detailed information for compound 91856

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 394.503 | Formula: C25H30O4
  • H donors: 3 H acceptors: 4 LogP: 2.91 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCC/C=C/1\CC2C(C1)[C@H]([C@@H](C2)O)C#C[C@H](C1Cc2c(C1)cccc2)O
  • InChi: 1S/C25H30O4/c26-23(20-13-17-6-2-3-7-18(17)14-20)10-9-21-22-12-16(5-1-4-8-25(28)29)11-19(22)15-24(21)27/h2-3,5-7,19-24,26-27H,1,4,8,11-15H2,(H,28,29)/b16-5+/t19?,21-,22?,23-,24-/m1/s1
  • InChiKey: NESUQTAFEVGEOI-HJKRAMSPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0082 0.0638
Brugia malayi CXXC zinc finger family protein 0.0029 0.0116 0.0414
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0082 0.009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.011 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0038 0.0042
Loa Loa (eye worm) CYP4Cod1 0.002 0.0055 0.0146
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0465
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0038 0.0038
Echinococcus granulosus sphingomyelin synthase protein 1 0.0024 0.0082 0.0089
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0214 0.1278 0.1398
Entamoeba histolytica hypothetical protein 0.0111 0.0631 0.9392
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0024 0.0082 0.0291
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0294 0.2271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Onchocerca volvulus 0.0017 0.0038 0.0275
Schistosoma mansoni hypothetical protein 0.0078 0.0423 0.0463
Echinococcus multilocularis deoxyribonuclease 1 2 0.0012 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0024 0.0082 0.1213
Echinococcus multilocularis inositol monophosphatase 1 0.0118 0.0672 0.0672
Echinococcus granulosus inositol monophosphatase 1 0.0118 0.0672 0.0735
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0337 0.2606
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Onchocerca volvulus 0.0214 0.1278 1
Echinococcus granulosus importin subunit beta 1 0.0057 0.0292 0.0319
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0034 0.0034
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.142 0.3766
Echinococcus granulosus GPCR family 2 0.0078 0.0423 0.0463
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0096 0.0343
Schistosoma mansoni synaptojanin 0.0012 0.0005 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.1087 0.6679
Schistosoma mansoni hypothetical protein 0.0015 0.0027 0.0029
Echinococcus multilocularis calpain 0.002 0.0057 0.0057
Plasmodium falciparum DNase I-like protein, putative 0.0012 0.0005 0.0129
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0292 0.2281
Echinococcus multilocularis lamin 0.0026 0.0096 0.0096
Echinococcus granulosus calpain 5 0.002 0.0057 0.0062
Schistosoma mansoni hypothetical protein 0.0078 0.0423 0.0463
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0292 0.2281
Echinococcus granulosus Smad4 0.0016 0.0033 0.0037
Schistosoma mansoni ran 0.0021 0.0064 0.007
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0082 0.0501
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0294 0.1759
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0012 0.0005 0.004
Onchocerca volvulus 0.0047 0.0227 0.1757
Brugia malayi Bromodomain containing protein 0.0041 0.0192 0.0687
Schistosoma mansoni bromodomain containing protein 0.0068 0.0358 0.0391
Plasmodium falciparum importin beta, putative 0.0057 0.0292 0.734
Leishmania major kinesin, putative 0.002 0.0057 0.0446
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0141 0.0154
Echinococcus granulosus smad 0.0016 0.0033 0.0037
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0408
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0008
Brugia malayi intermediate filament protein 0.0026 0.0096 0.0343
Echinococcus multilocularis lysosomal alpha glucosidase 0.0343 0.2086 0.2086
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0012 0.0005 0.0129
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0416
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0337 0.2606
Entamoeba histolytica calpain large subunit domain III containing protein 0.002 0.0057 0.0849
Schistosoma mansoni calpain (C02 family) 0.002 0.0057 0.0062
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0038 0.0299
Loa Loa (eye worm) beta-lactamase 0.0214 0.1278 0.339
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0107
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0672 0.4128
Onchocerca volvulus Putative neutral sphingomyelinase 0.0012 0.0005 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0397 1
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.018 0.6047
Echinococcus granulosus tumor protein p63 0.0672 0.4157 0.4546
Onchocerca volvulus 0.0012 0.0005 0.0016
Trypanosoma brucei ISWI complex protein 0.0015 0.0027 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0294 0.1052
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0012 0.0005 0.0076
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.017
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0012 0.001 0.001
Trichomonas vaginalis penicillin-binding protein, putative 0.0214 0.1278 0.7854
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.2046
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Echinococcus multilocularis cysteine protease 0.0017 0.0038 0.0038
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.007 0.0374 0.0409
Echinococcus granulosus neutral alpha glucosidase AB 0.0076 0.041 0.0448
Loa Loa (eye worm) hypothetical protein 0.0078 0.0423 0.1122
Mycobacterium tuberculosis Probable lipase LipD 0.0214 0.1278 0.1493
Loa Loa (eye worm) hypothetical protein 0.0257 0.1545 0.4098
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0601
Brugia malayi hypothetical protein 0.0257 0.1545 0.5525
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0423 0.1513
Loa Loa (eye worm) glutaminase 0.027 0.1628 0.4316
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0217 0.0238
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0397 0.308
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.011 0.1637
Trypanosoma cruzi kinesin, putative 0.002 0.0057 0.0408
Leishmania major cathepsin L-like protease 0.0017 0.0038 0.0299
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0038 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0866 0.0866
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0077 0.0416
Loa Loa (eye worm) hypothetical protein 0.0047 0.023 0.0609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.004 0.0041
Brugia malayi MH2 domain containing protein 0.0016 0.0033 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Brugia malayi MH2 domain containing protein 0.0237 0.142 0.5078
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0118 0.0672 0.5256
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0601
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0005 0.0031
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0294 0.078
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0012 0.0005 0.0006
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0012 0.0005 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0067 0.0352 0.0934
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0038 0.0963
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0005 0.0129
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0189 0.112 0.4003
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.1545 0.1545
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0003 0.0047
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0214 0.1278 0.339
Schistosoma mansoni ran 0.0021 0.0064 0.007
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0423 0.0463
Echinococcus granulosus neuropeptide s receptor 0.048 0.2949 0.3226
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0057 0.0408
Schistosoma mansoni hypothetical protein 0.0078 0.0423 0.0463
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.004 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0038 0.0569
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0423 0.0423
Mycobacterium ulcerans lipase LipD 0.0214 0.1278 0.7842
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0038 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.041 0.318
Brugia malayi beta-lactamase 0.0214 0.1278 0.4571
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0012 0.001 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0204
Echinococcus multilocularis geminin 0.0866 0.5371 0.5371
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0012 0.001 0.001
Schistosoma mansoni calpain-7 (C02 family) 0.0026 0.0095 0.0104
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0082 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0224 0.1716
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0423 0.1513
Echinococcus granulosus inositol monophosphatase 0.0012 0.001 0.001
Trypanosoma brucei calpain-like protein, putative 0.002 0.0057 0.0446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0408
Schistosoma mansoni hypothetical protein 0.0012 0.0005 0.0006
Leishmania major hypothetical protein, conserved 0.0012 0.0005 0.004
Schistosoma mansoni nocturnin 0.0012 0.0005 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0214 0.1278 0.7854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Echinococcus granulosus cathepsin l1 0.0017 0.0038 0.0042
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0005 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.041 0.2519
Onchocerca volvulus 0.0098 0.055 0.4291
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0.0005 0.0031
Entamoeba histolytica Ran family GTPase 0.0021 0.0064 0.0957
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0064 0.0064
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0024 0.0082 0.2052
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.002 0.0053
Echinococcus multilocularis calpain 7 (C02 family) 0.002 0.0057 0.0057
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Entamoeba histolytica hypothetical protein 0.0046 0.0224 0.3328
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0275
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0294 0.1808
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.041 0.2519
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0003 0.0019
Brugia malayi CCR4 0.0012 0.0005 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.041 0.2519
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0012 0.0005 0.0005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0076 0.041 0.1466
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.025 0.1925
Echinococcus multilocularis microtubule associated protein 2 0.1466 0.9143 0.9143
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0003 0.0003
Echinococcus granulosus traf and tnf receptor associated protein 0.0012 0.0005 0.0006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.041 0.2519
Schistosoma mansoni hypothetical protein 0.0033 0.0141 0.0154
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.011 0.0676
Loa Loa (eye worm) hypothetical protein 0.0189 0.112 0.2969
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0082 0.0638
Echinococcus multilocularis neutral alpha glucosidase AB 0.0076 0.041 0.041
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.004
Loa Loa (eye worm) hypothetical protein 0.0074 0.0397 0.1053
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0003 0.0019
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0408
Loa Loa (eye worm) calpain 0.002 0.0057 0.0151
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0077 0.0084
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0217 0.1334
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Mycobacterium tuberculosis Probable hydrolase 0.0214 0.1278 0.1493
Brugia malayi Inositol monophosphatase family protein 0.0012 0.001 0.0034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0024 0.0082 0.2052
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0055 0.0281
Leishmania major cathepsin L-like protease 0.0064 0.0337 0.2635
Trypanosoma brucei calpain-like protein, putative 0.002 0.0057 0.0446
Leishmania major hypothetical protein, conserved 0.0012 0.0005 0.004
Schistosoma mansoni ap endonuclease 0.0058 0.0294 0.0322
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0012 0.001 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.041 0.2519
Trypanosoma brucei cytochrome P450, putative 0.002 0.0055 0.043
Entamoeba histolytica hypothetical protein 0.0024 0.0082 0.1213
Echinococcus granulosus calpain A 0.007 0.0374 0.0409
Loa Loa (eye worm) Smad1 0.0016 0.0033 0.0089
Echinococcus granulosus neutral sphingomyelinase 0.0012 0.0005 0.0006
Mycobacterium tuberculosis Probable monophosphatase 0.0012 0.001 0.0005
Schistosoma mansoni pap-inositol-14-phosphatase 0.0012 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0101
Leishmania major cathepsin L-like protease 0.0017 0.0038 0.0299
Brugia malayi Inositol-1 0.0118 0.0672 0.2402
Plasmodium vivax sphingomyelin synthase 2, putative 0.0024 0.0082 0.0638
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0155 0.0155
Brugia malayi hypothetical protein 0.0074 0.0397 0.142
Loa Loa (eye worm) glutaminase 2 0.027 0.1628 0.4316
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0292 0.2281
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Echinococcus granulosus geminin 0.0866 0.5371 0.5875
Schistosoma mansoni Smad4 0.0016 0.0033 0.0037
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.011 0.0676
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.1278 0.7854
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0397 0.3108
Loa Loa (eye worm) PHD-finger family protein 0.002 0.006 0.0159
Leishmania major alpha glucosidase II subunit, putative 0.0076 0.041 0.3207
Loa Loa (eye worm) acetyltransferase 0.0149 0.0866 0.2298
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0294 1
Entamoeba histolytica hypothetical protein 0.0024 0.0082 0.1213
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0024 0.0082 0.0638
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0005 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0337 0.2606
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Loa Loa (eye worm) hypothetical protein 0.007 0.0371 0.0983
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0118 0.0672 0.4094
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0005 0.0129
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0005 0.0014
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0005 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0077 0.1143
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1369 0.8534 1
Echinococcus multilocularis neuropeptide s receptor 0.048 0.2949 0.2949
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0408
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0214 0.1278 0.7842
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0.0005 0.0031
Schistosoma mansoni alpha-glucosidase 0.0295 0.1786 0.1953
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0038 0.0963
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0816 0.0892
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0005 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0397 0.308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0042 0.0046
Toxoplasma gondii ABC1 family protein 0.0214 0.1278 1
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0082 0.0291
Schistosoma mansoni Mername-AA248 (C02 family) 0.002 0.0057 0.0062
Loa Loa (eye worm) hypothetical protein 0.0057 0.0292 0.0773
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0684 0.417
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0012 0.001 0.0059
Leishmania major importin beta-1 subunit, putative 0.0046 0.0224 0.1749
Trypanosoma brucei antigen, putative 0.002 0.0057 0.0446
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Entamoeba histolytica hypothetical protein 0.0024 0.0082 0.1213
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0025
Brugia malayi Smad1 0.0016 0.0033 0.0119
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.002 0.0071
Schistosoma mansoni hypothetical protein 0.0866 0.5371 0.5875
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0216
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0064 0.0503
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0204
Echinococcus granulosus cpg binding protein 0.0033 0.0138 0.0151
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0082 0.0638
Echinococcus multilocularis hypothetical protein 0.002 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.1278 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Onchocerca volvulus 0.0012 0.0005 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Schistosoma mansoni lamin 0.0026 0.0096 0.0105
Schistosoma mansoni cript-related 0.0012 0.0005 0.0006
Mycobacterium tuberculosis Conserved protein 0.0214 0.1278 0.1493
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0076 0.041 0.1087
Trypanosoma brucei calpain-like protein, putative 0.002 0.0057 0.0446
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0335 0.0335
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0077 0.1143
Loa Loa (eye worm) hypothetical protein 0.0026 0.0096 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0012 0.001 0.001
Schistosoma mansoni smad1 5 8 and 0.0016 0.0033 0.0037
Mycobacterium ulcerans beta-lactamase 0.0214 0.1278 0.7842
Loa Loa (eye worm) hypothetical protein 0.0047 0.0227 0.0603
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.002 0.0057 0.0446
Echinococcus multilocularis beta LACTamase domain containing family member 0.0214 0.1278 0.1278
Plasmodium vivax exodeoxyribonuclease III, putative 0.0012 0.0005 0.004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0214 0.1278 0.1493
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0672 0.5256
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0012 0.0005 0.0076
Trichomonas vaginalis sucrase-isomaltase, putative 0.0076 0.041 0.2519
Echinococcus granulosus synaptojanin 1 0.0012 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0005 0.0014
Trichomonas vaginalis esterase, putative 0.0214 0.1278 0.7854
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0446
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0294 0.2271
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0077 0.0601
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0214 0.1278 0.4571
Loa Loa (eye worm) calpain family protein 1 0.0067 0.0352 0.0934
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0034 0.0034
Brugia malayi Cytochrome P450 family protein 0.002 0.0055 0.0196
Schistosoma mansoni cpg binding protein 0.0033 0.0138 0.0151
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.142 0.3766
Trypanosoma cruzi ISWI complex protein 0.0015 0.0027 0.0171
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0672 0.5256
Loa Loa (eye worm) fibroinase 0.0017 0.0038 0.0101
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0446
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0684 0.417
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.001 0.0059
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0294 1
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0.0005 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0242 0.064
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0005 0.0005
Trichomonas vaginalis hypothetical protein 0.0024 0.0082 0.0501
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0005 0.0076
Echinococcus granulosus lysosomal alpha glucosidase 0.0343 0.2086 0.2281
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0204
Echinococcus multilocularis traf and tnf receptor associated protein 0.0012 0.0005 0.0005
Schistosoma mansoni synaptojanin 0.0012 0.0005 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.255 0.255
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0096 0.0255
Leishmania major hypothetical protein, conserved 0.0012 0.0005 0.004
Loa Loa (eye worm) hypothetical protein 0.0098 0.055 0.1459
Plasmodium vivax sphingomyelin synthase 1, putative 0.0024 0.0082 0.0638
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0012 0.0005 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Trichomonas vaginalis inositol monophosphatase, putative 0.0118 0.0672 0.4128
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.018 0.4529
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.011 0.0824
Echinococcus multilocularis neutral sphingomyelinase 0.0012 0.0005 0.0005
Onchocerca volvulus 0.0017 0.0038 0.0275
Leishmania major cytochrome p450-like protein 0.002 0.0055 0.043
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0038 0.0038
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.001 0.0142
Schistosoma mansoni smad1 5 8 and 0.0016 0.0033 0.0037
Leishmania major cathepsin L-like protease 0.0017 0.0038 0.0299
Brugia malayi Inositol monophosphatase family protein 0.0012 0.001 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0294 0.0294
Brugia malayi MH1 domain containing protein 0.0016 0.0033 0.0119
Entamoeba histolytica hypothetical protein 0.0111 0.0631 0.9392
Schistosoma mansoni cpg binding protein 0.0029 0.0116 0.0127
Schistosoma mansoni hypothetical protein 0.0866 0.5371 0.5875
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Onchocerca volvulus 0.0017 0.0038 0.0275
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0672 0.5237
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0038 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.1278 0.7854
Toxoplasma gondii exonuclease III APE 0.0058 0.0294 0.2302
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0005 0.004
Echinococcus multilocularis tumor protein p63 0.0672 0.4157 0.4157
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0077 0.0416
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.055 0.0602
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0022
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.1618
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0866 0.3098
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0082 0.0501
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0012 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Mycobacterium ulcerans esterase/lipase LipP 0.0214 0.1278 0.7842
Plasmodium vivax importin-beta 2, putative 0.0057 0.0292 0.2281
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0216
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0261 0.0933
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0014
Onchocerca volvulus 0.0017 0.0038 0.0275
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0816 0.0892
Brugia malayi calpain family protein 1 0.0067 0.0352 0.126
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0247 0.1484 0.5306
Plasmodium vivax vivapain-2 0.0017 0.0038 0.0299
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0416
Schistosoma mansoni inositol monophosphatase 0.0118 0.0672 0.0735
Onchocerca volvulus 0.0052 0.0261 0.2023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0008
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0012 0.0005 0.004
Brugia malayi RNA, U transporter 1 0.0163 0.0955 0.3413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0057 0.0408
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Trypanosoma cruzi kinesin, putative 0.002 0.0057 0.0408
Entamoeba histolytica cysteine protease, putative 0.0017 0.0038 0.0569
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0423 0.1122
Onchocerca volvulus 0.0214 0.1278 1
Trichomonas vaginalis glutaminase, putative 0.027 0.1628 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0247 0.1484 0.5306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0012 0.001 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0337 0.2606
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0611 0.3771 1
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0082 0.0501
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0064 0.017
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0012 0.0005 0.0076
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0024 0.0082 0.2052
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0038 0.0963
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0038 0.026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0816 0.0816
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0038 0.0101
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.1545 0.169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0034 0.0034
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0684 0.0748
Echinococcus multilocularis synaptojanin 1 0.0012 0.0005 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.0684 0.0748
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.023
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0294 0.2302
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.004 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0214 0.1278 0.1398
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0826 0.0903
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0816 0.2917
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0397 1
Echinococcus granulosus microtubule associated protein 2 0.1466 0.9143 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0033 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.041 0.2519
Onchocerca volvulus 0.0017 0.0038 0.0275
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0816 0.2164
Echinococcus multilocularis musashi 0.0026 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0224 0.1374
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0005 0.0076
Echinococcus granulosus lamin 0.0026 0.0096 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma brucei RNA editing exonuclease 2 0.0012 0.0005 0.004
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0456 0.2797 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.0292
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.0684 0.5352
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Onchocerca volvulus 0.0029 0.0116 0.0884
Brugia malayi latrophilin 2 splice variant baaae 0.0169 0.0993 0.355
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0216
Toxoplasma gondii cathepsin CPL 0.0017 0.0038 0.0299
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.0076
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0038 0.0101
Leishmania major GTP-binding protein, putative 0.0021 0.0064 0.0503
Schistosoma mansoni calpain C (C02 family) 0.002 0.0057 0.0062
Brugia malayi beta-lactamase family protein 0.0214 0.1278 0.4571
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0.0005 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0055 0.0146
Brugia malayi calpain 5 0.002 0.0057 0.0204
Brugia malayi hypothetical protein 0.0048 0.0232 0.0831
Trypanosoma brucei glucosidase, putative 0.0076 0.041 0.3207
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0217 0.1699
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0012 0.001 0.0075
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.0684 0.0684
Brugia malayi beta-lactamase family protein 0.0214 0.1278 0.4571
Schistosoma mansoni cpg binding protein 0.0033 0.0138 0.0151
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0224 0.1374
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0012 0.001 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0446
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.0684 0.5352
Schistosoma mansoni microtubule-associated protein tau 0.1466 0.9143 1
Mycobacterium leprae Probable lipase LipE 0.0214 0.1278 1
Schistosoma mansoni carbon catabolite repressor protein 0.0012 0.0005 0.0006
Leishmania major cathepsin L-like protease 0.0017 0.0038 0.0299
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0012 0.001 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0107
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0057 0.0408
Echinococcus granulosus snurportin 1 0.0611 0.3771 0.4125
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.041 0.6101
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.011 0.0838
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0335 0.0367
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.011 0.0676
Brugia malayi calpain family protein 1 0.0067 0.0352 0.126
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0005 0.0014
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0005 0.0014
Brugia malayi calpain 7 0.002 0.0057 0.0204
Schistosoma mansoni glutaminase 0.027 0.1628 0.178
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0423 0.0463
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.0684 0.0796
Schistosoma mansoni smad 0.0016 0.0033 0.0037
Echinococcus multilocularis calpain A 0.007 0.0374 0.0374
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0294 0.7406
Schistosoma mansoni lamin 0.0026 0.0096 0.0105
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.041 0.318
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0866 0.0948
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0217 0.1699
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0077 0.053
Loa Loa (eye worm) hypothetical protein 0.0067 0.0352 0.0934
Toxoplasma gondii hypothetical protein 0.0012 0.001 0.0075
Mycobacterium tuberculosis Monophosphatase CysQ 0.0012 0.001 0.0005
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0082 0.009
Trichomonas vaginalis maltase-glucoamylase, putative 0.0076 0.041 0.2519
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0038 0.0569
Echinococcus granulosus calpain 7 C02 family 0.002 0.0057 0.0062
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.001 0.0059
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0005 0.004
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0055 0.0391
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0005 0.004
Trypanosoma brucei inositol phosphorylceramide synthase 0.0024 0.0082 0.0638
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0038 0.0235
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0816 0.0816
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0034 0.0034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0294 0.4379
Schistosoma mansoni hypothetical protein 0.0111 0.0631 0.069
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0082 0.06
Echinococcus granulosus zinc finger protein 0.0025 0.0086 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0423 0.0423
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0294 0.0322
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0038 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0247
Schistosoma mansoni neutral sphingomyelinase 0.0012 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0247 0.1484 0.3935
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0216
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0631 0.069
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0503
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.002 0.0057 0.0446
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.001 0.0142
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0.0005 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.041 0.2519
Brugia malayi cathepsin L-like precursor 0.0011 0.0003 0.0011
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0033 0.0037
Echinococcus multilocularis zinc finger protein 0.0025 0.0086 0.0086
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.041 0.6101
Leishmania major cathepsin L-like protease 0.0064 0.0337 0.2635
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0155 0.0169
Toxoplasma gondii hypothetical protein 0.0024 0.0082 0.0638
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0033 0.0037
Brugia malayi PHD-finger family protein 0.003 0.012 0.0427
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0038 0.0038
Echinococcus multilocularis snurportin 1 0.0611 0.3771 0.3771
Brugia malayi Glycosyl hydrolases family 31 protein 0.0343 0.2086 0.7458
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0672 0.4128
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0294 0.1808
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0082 0.0501
Loa Loa (eye worm) calpain family protein 1 0.0047 0.0227 0.0603
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0631 0.0631
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0816 0.0892
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0055 0.0391
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0247 0.1484 0.3935
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0105 0.0594 0.0691
Schistosoma mansoni spingomyelin synthetase-related 0.0024 0.0082 0.0089
Schistosoma mansoni hypothetical protein 0.0078 0.0423 0.0463
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0038 0.0038
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0024 0.0082 0.0291
Echinococcus multilocularis neuropeptide receptor A26 0.048 0.2949 0.2949
Echinococcus granulosus dnaJ subfamily B 0.0417 0.255 0.2789
Brugia malayi MH1 domain containing protein 0.0016 0.0033 0.0119
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Leishmania major pantothenate kinase subunit, putative 0.0013 0.0011 0.0086
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0214 0.1278 0.1493
Leishmania major hypothetical protein, conserved 0.0214 0.1278 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0352 0.0385
Brugia malayi Bromodomain containing protein 0.0079 0.043 0.1538
Schistosoma mansoni hypothetical protein 0.0611 0.3771 0.4125
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0107
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.004 0.1012
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0038 0.0275
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Entamoeba histolytica hypothetical protein 0.0024 0.0082 0.1213
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0014
Brugia malayi glutaminase DH11.1 0.027 0.1628 0.582
Brugia malayi Cathepsin L-like precursor 0.0017 0.0038 0.0137
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0005 0.004
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.007 0.0374 0.0409
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0343 0.2086 0.5531
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Onchocerca volvulus 0.0198 0.1178 0.9211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Entamoeba histolytica hypothetical protein 0.0111 0.0631 0.9392
Echinococcus multilocularis GPCR, family 2 0.0078 0.0423 0.0423
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Loa Loa (eye worm) ctsf protein 0.0017 0.0038 0.0101
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0631 0.069
Loa Loa (eye worm) inositol-1 0.0118 0.0672 0.1782
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0077 0.0084
Mycobacterium tuberculosis Probable esterase LipL 0.0214 0.1278 0.1493
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0214 0.1278 0.1493
Brugia malayi Cathepsin L-like precursor 0.0011 0.0003 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0033 0.0089
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0038 0.0275
Loa Loa (eye worm) hypothetical protein 0.0044 0.0207 0.0549
Schistosoma mansoni hypothetical protein 0.0052 0.0261 0.0286
Plasmodium vivax hypothetical protein, conserved 0.0214 0.1278 1
Echinococcus multilocularis cysteine protease 0.0017 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.018 0.2678
Loa Loa (eye worm) hypothetical protein 0.0456 0.2797 0.7417
Brugia malayi hypothetical protein 0.0111 0.0631 0.2256
Schistosoma mansoni survival motor neuron protein 0.0052 0.0261 0.0286
Brugia malayi Importin beta-1 subunit 0.0057 0.0292 0.1043
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0076 0.041 0.3207
Entamoeba histolytica hypothetical protein 0.0111 0.0631 0.9392
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0816 0.0892
Echinococcus granulosus cathepsin l1 0.0011 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0038 0.0235
Trypanosoma cruzi calpain cysteine peptidase, putative 0.002 0.0057 0.0408
Giardia lamblia Hypothetical protein 0.0012 0.001 0.0153
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.007 0.0374 0.0374
Onchocerca volvulus 0.0023 0.0077 0.0578
Trypanosoma brucei kinesin, putative 0.002 0.0057 0.0446
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0096 0.0255
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0064 0.007
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0064 0.0503
Plasmodium vivax vivapain-2 0.0017 0.0038 0.0299
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0011 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0038 0.0137
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0397 0.3108
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0116 0.0307
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0317 0.2483
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0055 0.0146
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0033 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0038 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Mycobacterium ulcerans hypothetical protein 0.0214 0.1278 0.7842
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0012 0.0005 0.0006
Mycobacterium tuberculosis Conserved protein 0.0214 0.1278 0.1493
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Leishmania major endonuclease/exonuclease protein-like protein 0.0012 0.0005 0.004
Onchocerca volvulus 0.0017 0.0038 0.0275
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0077 0.0275
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.011 0.0676
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0294 0.0339
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0294 0.2302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0235
Plasmodium vivax calpain, putative 0.002 0.0057 0.0446
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0024 0.0082 0.0082
Onchocerca volvulus 0.0017 0.0038 0.0275
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0077 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0111
Echinococcus granulosus neuropeptide receptor A26 0.048 0.2949 0.3226
Echinococcus multilocularis cpg binding protein 0.0033 0.0138 0.0138
Schistosoma mansoni importin beta-1 0.0057 0.0292 0.0319
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0033 0.0037
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0005 0.0006
Schistosoma mansoni myo inositol monophosphatase 0.0012 0.001 0.001
Brugia malayi Cathepsin L-like precursor 0.0011 0.0003 0.0011
Echinococcus multilocularis smad 0.0016 0.0033 0.0033
Schistosoma mansoni smad1 5 8 and 0.0016 0.0033 0.0037
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0082 0.0291
Schistosoma mansoni hypothetical protein 0.0012 0.001 0.001
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0082 0.06
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Echinococcus granulosus calpain A 0.002 0.0057 0.0062
Leishmania major RNA-editing complex protein MP100, putative 0.0012 0.0005 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0038 0.0041
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Echinococcus granulosus lamin dm0 0.0026 0.0096 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.1278 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0343 0.2086 0.2086
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0294 0.2302
Schistosoma mansoni zinc finger protein 0.0025 0.0086 0.0095
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0057 0.0408
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0292 0.0292
Trichomonas vaginalis ran, putative 0.0021 0.0064 0.0395
Leishmania major hypothetical protein, conserved 0.0015 0.0027 0.021
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0012 0.001 0.0035
Schistosoma mansoni intermediate filament proteins 0.0026 0.0096 0.0105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0322 0.0352
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0005 0.004
Schistosoma mansoni hypothetical protein 0.0169 0.0993 0.1086
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0077 0.0416
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0141 0.0141
Echinococcus multilocularis Smad4 0.0016 0.0033 0.0033
Trypanosoma brucei hypothetical protein, conserved 0.0214 0.1278 1
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0038 0.0042
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.011 0.0676
Entamoeba histolytica protein kinase, putative 0.002 0.0057 0.0849
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0118 0.0672 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.017 0.0451
Brugia malayi Cytochrome P450 family protein 0.002 0.0055 0.0196
Mycobacterium ulcerans glutaminase 0.027 0.1628 1
Schistosoma mansoni inositol monophosphatase 0.0118 0.0672 0.0735
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0684 0.417
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.011 0.0393
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0005 0.004
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.004 0.0315
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0038 0.0042
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0217 0.1699
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.011 0.0676
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.011 0.0676
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0077 0.0416
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.011 0.0824
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0012 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0417 0.255 0.2789
Leishmania major cathepsin L-like protease 0.0064 0.0337 0.2635
Trypanosoma cruzi ISWI complex protein 0.0015 0.0027 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0216
Schistosoma mansoni ap endonuclease 0.0058 0.0294 0.0322
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0042 0.0046
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0169 0.0993 0.2633
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0012 0.0005 0.0129
Echinococcus granulosus intermediate filament protein 0.0026 0.0096 0.0105
Mycobacterium tuberculosis Probable lipase LipE 0.0214 0.1278 0.1493
Leishmania major cathepsin L-like protease 0.0017 0.0038 0.0299
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0082 0.0082
Schistosoma mansoni zinc finger protein 0.0015 0.0027 0.0029
Brugia malayi Sphingomyelin synthase-related 1 0.0024 0.0082 0.0291
Schistosoma mansoni hypothetical protein 0.002 0.006 0.0066
Onchocerca volvulus 0.0026 0.0096 0.0729
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0105 0.0594 0.4609
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0672 0.5237
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0465
Loa Loa (eye worm) calpain 5 0.002 0.0057 0.0151
Echinococcus multilocularis calpain family protein 1, d 0.0047 0.0227 0.0227
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0013 0.0011 0.0046
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.007 0.0374 0.0409
Echinococcus granulosus calpain 0.002 0.0057 0.0062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0047 0.0227 0.0603
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0025
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0217 0.1334
Leishmania major myo-inositol-1 phosphatase, putative 0.0012 0.001 0.0075
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0224 0.1374
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0012 0.0005 0.004
Mycobacterium ulcerans hypothetical protein 0.0023 0.0077 0.0416
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0302 0.233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0337 0.2635
Onchocerca volvulus 0.0214 0.1278 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0077 0.0416
Brugia malayi Cytochrome P450 family protein 0.0049 0.0242 0.0864
Schistosoma mansoni calpain-7 (C02 family) 0.0026 0.0095 0.0104
Trypanosoma brucei calpain-like protein, putative 0.002 0.0057 0.0446
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0057 0.0408
Echinococcus multilocularis lamin dm0 0.0026 0.0096 0.0096
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0118 0.0672 1
Brugia malayi MH2 domain containing protein 0.0016 0.0033 0.0119
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0077 0.1143
Loa Loa (eye worm) hypothetical protein 0.0214 0.1278 0.339
Loa Loa (eye worm) cysteine protease 0.0017 0.0038 0.0101
Echinococcus multilocularis calpain 5 0.002 0.0057 0.0057
Onchocerca volvulus 0.0026 0.0096 0.0729
Echinococcus granulosus beta LACTamase domain containing family member 0.0214 0.1278 0.1398
Entamoeba histolytica hypothetical membrane-spanning protein 0.0024 0.0082 0.1213
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0003 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0816 0.0892
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.1278 0.7854
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.011 0.086
Echinococcus multilocularis inositol monophosphatase 0.0012 0.001 0.001
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0397 0.3108
Mycobacterium tuberculosis Conserved protein 0.0214 0.1278 0.1493
Schistosoma mansoni alpha-glucosidase 0.0295 0.1786 0.1953
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0684 0.0748
Leishmania major hypothetical protein, conserved 0.0074 0.0397 0.3108
Leishmania major glycosyl hydrolase-like protein 0.0028 0.011 0.086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0038 0.0235
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0107
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0042 0.0042
Schistosoma mansoni alpha glucosidase 0.0076 0.041 0.0448
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0.0005 0.0031
Mycobacterium leprae conserved hypothetical protein 0.0214 0.1278 1

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 1.7 ug kg-1 Inhibtion of ethanol induced gastric lesions in the rat following p.o. administration. ChEMBL. 2666669
IC50 (functional) = 8.2 ng ml-1 Antiaggregatory activity is expressed as dose that inhibit rat platelet aggregation induced by collagen by 50% of that of the control ChEMBL. 2666669
MBP (functional) = 1.3 ug kg-1 Dose that reduces mean blood pressure by 15 mmHg (peak effect) in rat administered intravenously ChEMBL. 2666669
Ratio (functional) = 1.8 Ratio of relative potencies of organ protection/ hypotension to that of PGI-2 Na in rats ChEMBL. 2666669
Ratio (functional) = 21.8 Ratio of relative potencies of organ protection/ hypotension to that of PGE-2 in rats ChEMBL. 2666669
Relative potency (functional) = 0.23 Relative potency of the compound for antiaggregation in rats ChEMBL. 2666669
Relative potency (functional) = 0.42 Relative potency of the compound forantiaggregation ChEMBL. 2666669
Relative potency (functional) = 0.9 Relative potency of the compound forhypotension in rats ChEMBL. 2666669
Relative potency (functional) = 20.1 Relative potency of the compound fororgan protection in rats ChEMBL. 2666669

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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