Detailed information for compound 921478

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 463.592 | Formula: C26H29N3O3S
  • H donors: 3 H acceptors: 3 LogP: 3.49 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)S(=O)(=O)N[C@@H]1CNC[C@@H](C1)C(=O)NC(c1ccccc1)c1ccccc1
  • InChi: 1S/C26H29N3O3S/c1-19-12-14-24(15-13-19)33(31,32)29-23-16-22(17-27-18-23)26(30)28-25(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,22-23,25,27,29H,16-18H2,1H3,(H,28,30)/t22-,23+/m1/s1
  • InChiKey: VKUDTVHFNVOHTR-PKTZIBPZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens renin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl proteinase (eimepsin), putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl protease ASP1 Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii plasmepsin Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin I Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin II Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus granulosus cathepsin d lysosomal aspartyl protease Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva pepsinogen, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum ko:K01379 cathepsin D [EC3.4.23.5], putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax aspartyl proteinase, putative Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) aspartic protease BmAsp-2 Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Pepsinogen A1, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi aspartyl protease, putative Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium parvum membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva cathepsin E, putative Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Renin, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium hominis aspartyl protease precursor Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum Cathepsin D precursor, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Babesia bovis eukaryotic aspartyl protease family protein Get druggable targets OG5_126885 All targets in OG5_126885
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin X renin 406 aa 352 aa 26.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trypanosoma brucei carbonic anhydrase-like protein 0.0181 0.1923 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.06 0.1773
Brugia malayi aspartic protease BmAsp-1, identical 0.0014 0.0024 0.0078
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0046 0.0101
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0096 0.0498
Schistosoma mansoni chromobox protein 0.0073 0.0697 0.1533
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Plasmodium falciparum plasmepsin IX 0.0014 0.0024 0.0024
Plasmodium falciparum plasmepsin IV 0.0059 0.0536 0.0536
Entamoeba histolytica Ran family GTPase 0.0021 0.0108 0.1045
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0201 0.1047
Leishmania major hypothetical protein, conserved 0.0051 0.045 0.2338
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Toxoplasma gondii hypothetical protein 0.0015 0.0041 0.0062
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.0041 0.0122
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0582 0.1861
Mycobacterium ulcerans epoxide hydrolase EphA 0.0167 0.1767 0.5653
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0606 0.1939
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0621 0.1367
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Onchocerca volvulus 0.0015 0.0041 0.0219
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.001 0.0054
Giardia lamblia Kinase, PLK 0.0103 0.1038 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0601 0.0908
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0201 0.0644
Brugia malayi major facilitator superfamily protein 0.003 0.0201 0.0644
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0601 0.0601
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0582 0.5606
Schistosoma mansoni carbonic anhydrase-related 0.0085 0.0832 0.1832
Echinococcus multilocularis carbonic anhydrase 0.0085 0.0832 0.1832
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Schistosoma mansoni DNA polymerase eta 0.002 0.0096 0.0211
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0278 0.0611
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.0041 0.0122
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0041 0.0091
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0004 0.0008
Toxoplasma gondii sugar transporter ST1 0.003 0.0201 0.0304
Echinococcus granulosus chromobox protein 1 0.0073 0.0697 0.1533
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0062
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.001 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0367 0.1174
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0041 0.0091
Onchocerca volvulus Putative transporter 0.003 0.0201 0.1108
Onchocerca volvulus 0.003 0.0201 0.1108
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0606 0.1939
Echinococcus multilocularis dna polymerase eta 0.002 0.0096 0.0211
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0016
Schistosoma mansoni memapsin-2 (A01 family) 0.0014 0.0024 0.0053
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0644
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0004 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0201 0.0304
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Toxoplasma gondii aspartyl protease ASP3 0.0014 0.0024 0.0037
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.06 0.1321
Echinococcus granulosus carbonic anhydrase 0.0085 0.0832 0.1832
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0004 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0096 0.0211
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0278 0.477
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0353 0.113
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0278 0.1112
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0041 0.0041
Echinococcus granulosus carbonic anhydrase 0.0085 0.0832 0.1832
Trichomonas vaginalis glucose transporter, putative 0.003 0.0201 0.0644
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0096 0.0307
Mycobacterium ulcerans beta-lactamase 0.0036 0.0278 0.0888
Echinococcus multilocularis serotonin transporter 0.0015 0.0041 0.0091
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0621 0.1367
Brugia malayi hypothetical protein 0.0033 0.0243 0.0777
Echinococcus granulosus Chromobox protein 3 0.0012 0.0002 0.0004
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0004 0.0011
Toxoplasma gondii cytochrome p450 superfamily protein 0.0053 0.0465 0.0704
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.001 0.0033
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0108 0.0564
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0096 0.0498
Schistosoma mansoni ran 0.0021 0.0108 0.0239
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0278 0.1112
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0114 0.1156 0.6012
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0087 0.0192
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0004 0.0008
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0053 0.0465 0.1489
Plasmodium falciparum plasmepsin III 0.0014 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.021 0.2253 0.7207
Plasmodium falciparum protein kinase 7 0.0594 0.6613 0.6613
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0181 0.1923 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.001 0.0033
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0019 0.0087 0.0474
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0582 0.1861
Echinococcus granulosus tar DNA binding protein 0.0066 0.0621 0.1367
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0181 0.1923 0.568
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0053 0.0465 0.242
Brugia malayi beta-lactamase family protein 0.0036 0.0278 0.0888
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1231 0.3636
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0644
Mycobacterium ulcerans glutaminase 0.0287 0.3126 1
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.1843 0.4055
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0201 0.0595
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0004 0.0008
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0004
Plasmodium falciparum carbonic anhydrase 0.0085 0.0832 0.0832
Trypanosoma cruzi hexose transporter, putative 0.0036 0.027 0.1406
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0053 0.0465 0.1864
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.0004 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0132
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0582 0.1718
Entamoeba histolytica protein kinase, putative 0.0065 0.06 0.5784
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0004 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0042 0.0133
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0053 0.0465 0.1864
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trypanosoma brucei unspecified product 0.0014 0.0024 0.0127
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1038 0.5395
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Schistosoma mansoni hypothetical protein 0.0348 0.3824 0.8417
Leishmania major importin beta-1 subunit, putative 0.0024 0.0133 0.0692
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0096 0.0211
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Onchocerca volvulus 0.003 0.0201 0.1108
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.001 0.0033
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0046 0.0101
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0085 0.0832 0.2458
Onchocerca volvulus 0.003 0.0201 0.1108
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.06 0.3121
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.0004 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.045 0.045
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0053 0.0465 0.1489
Echinococcus granulosus dna polymerase kappa 0.002 0.0096 0.0211
Schistosoma mansoni protein kinase 0.0065 0.06 0.1321
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.4544 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0167 0.1762 0.5204
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0047 0.0398 0.1177
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0181 0.1923 0.6154
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0062
Brugia malayi RNA, U transporter 1 0.0083 0.0804 0.2571
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0443
Brugia malayi Cytochrome P450 family protein 0.0053 0.0465 0.1489
Trypanosoma brucei unspecified product 0.002 0.0096 0.0498
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0606 0.315
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Schistosoma mansoni cpg binding protein 0.0031 0.0213 0.0469
Onchocerca volvulus Putative nachr subunit 0.0012 0.0004 0.0011
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0398 0.2072
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.016 0.0471
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0108 0.032
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0096 0.0498
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0436 0.1395
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.0004 0.0011
Plasmodium falciparum mitogen-activated protein kinase 2 0.034 0.3726 0.3726
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0278 0.1112
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0087 0.0192
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.119 0.2619
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0257
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Brugia malayi hypothetical protein 0.0012 0.0002 0.0005
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.001 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0411 0.0905
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0278 0.0888
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0133 0.0426
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0181 0.1923 0.4233
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0059 0.0536 0.118
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0053 0.0465 0.1864
Brugia malayi hypothetical protein 0.0014 0.0024 0.0078
Schistosoma mansoni chromobox protein 0.0012 0.0002 0.0004
Schistosoma mansoni cpg binding protein 0.0029 0.0194 0.0427
Echinococcus granulosus single minded 2 0.0036 0.0278 0.0611
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0053 0.0465 0.1489
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0108 0.0239
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0353 0.0777
Loa Loa (eye worm) RNA binding protein 0.0066 0.0621 0.1834
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0318 0.1274
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0005
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0443
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0201 0.0806
Onchocerca volvulus 0.003 0.0201 0.1108
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.001 0.0259
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0108 0.1045
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.1523 0.3353
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0024 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Toxoplasma gondii ABC1 family protein 0.0036 0.0278 0.042
Entamoeba histolytica protein kinase, putative 0.0065 0.06 0.5784
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0102 0.1024 0.2254
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0096 0.0307
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0278 0.0278
Mycobacterium tuberculosis Conserved protein 0.0036 0.0278 0.1112
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0621 0.1367
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0002 0.0002
Echinococcus granulosus serotonin transporter 0.0015 0.0041 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0033
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0002 0.0004
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0196 0.043
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0096 0.0307
Leishmania major hypothetical protein, conserved 0.003 0.0201 0.1047
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0053 0.0465 0.1489
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0562 0.1238
Onchocerca volvulus 0.003 0.0201 0.1108
Brugia malayi CHD4 protein 0.0014 0.002 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Onchocerca volvulus 0.0012 0.0004 0.0011
Echinococcus granulosus importin subunit beta 1 0.0029 0.0196 0.043
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Schistosoma mansoni rab6-interacting 0.0019 0.0087 0.0192
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0196 0.0296
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0333 0.1065
Loa Loa (eye worm) glutaminase 2 0.0287 0.3126 0.923
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0004 0.0008
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0601 0.0601
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Echinococcus multilocularis GPCR, family 2 0.0016 0.0046 0.0101
Mycobacterium leprae Possible regulatory protein 0.0013 0.001 0.0177
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0582 0.128
Brugia malayi hypothetical protein 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0072
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0132
Brugia malayi hypothetical protein 0.0051 0.045 0.1439
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0465 0.1374
Onchocerca volvulus 0.0036 0.0278 0.1531
Brugia malayi Sugar transporter family protein 0.021 0.2253 0.7207
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0644
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0076 0.0244
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1038 0.3065
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0606 0.315
Schistosoma mansoni glucose transporter 0.003 0.0201 0.0443
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0041 0.0091
Echinococcus granulosus GPCR family 2 0.0016 0.0046 0.0101
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0087 0.0257
Giardia lamblia Sugar-proton symporter 0.003 0.0201 0.194
Onchocerca volvulus 0.003 0.0201 0.1108
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0053 0.0465 0.1489
Loa Loa (eye worm) helicase 0.0012 0.0002 0.0005
Brugia malayi hypoxia-induced factor 1 0.0152 0.1588 0.508
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0059 0.0536 0.0811
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.001 0.0023
Toxoplasma gondii hypothetical protein 0.0085 0.0832 0.1259
Onchocerca volvulus 0.003 0.0201 0.1108
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Mycobacterium tuberculosis Conserved protein 0.0036 0.0278 0.1112
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0004 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0133 0.0426
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.0004 0.0012
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0041 0.1033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0076 0.0244
Leishmania major glucose transporter, lmgt3 0.0065 0.0606 0.315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1038 0.5749
Brugia malayi SET domain containing protein 0.0013 0.0009 0.0028
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1038 0.5395
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0255 0.0817
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0096 0.0307
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0398 0.1275
Onchocerca volvulus 0.0032 0.0231 0.1271
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0004 0.0008
Brugia malayi Cation transporter family protein 0.0012 0.0004 0.0012
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0582 0.128
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0601 0.0601
Toxoplasma gondii aspartyl protease 0.0014 0.0024 0.0037
Loa Loa (eye worm) hypothetical protein 0.0051 0.045 0.1328
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0411 0.0905
Onchocerca volvulus 0.0015 0.0041 0.0219
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Conserved protein 0.0036 0.0278 0.1112
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0367 0.2026
Loa Loa (eye worm) serotonin transporter b 0.0015 0.0041 0.0122
Loa Loa (eye worm) cytochrome P450 0.0053 0.0465 0.1374
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Brugia malayi Sugar transporter family protein 0.003 0.0201 0.0644
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0096 0.0924
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1588 0.4689
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Schistosoma mansoni loxhd1 0.0019 0.0087 0.0192
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Plasmodium falciparum transporter, putative 0.0015 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0053 0.0465 0.1864
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.1232 0.2711
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.0443
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0398 0.0877
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0114 0.1156 0.2545
Loa Loa (eye worm) hypothetical protein 0.0102 0.1024 0.3025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0041 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1038 0.2284
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1038 0.2284
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1038 0.5395
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1908 0.6105
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0002 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0469 0.15
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0411 0.0905
Loa Loa (eye worm) carbonic anhydrase 3 0.0181 0.1923 0.568
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0398 0.2072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0398 0.384
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Trypanosoma brucei unspecified product 0.0014 0.0024 0.0127
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0398 0.6849
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0278 0.1443
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.2467 0.7284
Schistosoma mansoni protein kinase 0.0065 0.06 0.1321
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0606 0.1939
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0053 0.0465 0.1489
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0046 0.0148
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.034 0.3726 0.3726
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0127
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0465 0.1374
Echinococcus granulosus geminin 0.0348 0.3824 0.8417
Trichomonas vaginalis glutaminase, putative 0.0287 0.3126 1
Schistosoma mansoni glucose transport protein 0.021 0.2253 0.4958
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0013 0.0009 0.002
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0201 0.0443
Onchocerca volvulus 0.003 0.0201 0.1108
Onchocerca volvulus 0.003 0.0201 0.1108
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0398 0.1275
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0411 0.0905
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0053 0.0465 0.1489
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0059 0.0536 0.1583
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0697 0.2057
Loa Loa (eye worm) hypothetical protein 0.005 0.0436 0.1287
Schistosoma mansoni glutaminase 0.0287 0.3126 0.6879
Loa Loa (eye worm) glutaminase 0.0287 0.3126 0.923
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0059 0.0536 0.1716
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0002 0.0004
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0041 0.0091
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0353 0.0534
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.07 0.07
Onchocerca volvulus 0.003 0.0201 0.1108
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Plasmodium vivax aspartyl protease, putative 0.0014 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0085 0.0832 0.2458
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0465 0.242
Leishmania major hypothetical protein, conserved 0.0036 0.0278 0.1443
Trypanosoma brucei glucose transporter 1E 0.0065 0.0606 0.315
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0601 0.0908
Mycobacterium leprae Probable lipase LipE 0.0036 0.0278 0.477
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0085 0.0832 0.2663
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0002 0.0003
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0087 0.0192
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0016
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0053 0.0465 0.1489
Loa Loa (eye worm) hypothetical protein 0.002 0.0096 0.0283
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.0004 0.0008
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.1804 1
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0192
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Brugia malayi hypothetical protein 0.003 0.0201 0.0644
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0087 0.0192
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0697 0.2229
Loa Loa (eye worm) LGC-31 protein 0.0012 0.0004 0.0011
Brugia malayi Cytochrome P450 family protein 0.0053 0.0465 0.1489
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.3386 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.07 0.1059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0529 0.0799
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Brugia malayi chromobox protein homolog 3 0.0041 0.0331 0.106
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0196 0.1016
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.001 0.0033
Brugia malayi aspartic protease BmAsp-2, identical 0.0014 0.0024 0.0078
Plasmodium vivax aspartyl protease, putative 0.0014 0.0024 0.0024
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0085 0.0832 0.2663
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0621 0.1367
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0621 0.1834
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Loa Loa (eye worm) sugar transporter 0.021 0.2253 0.6652
Brugia malayi Importin beta-1 subunit 0.0029 0.0196 0.0626
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0278 0.0888
Entamoeba histolytica hypothetical protein 0.0047 0.0398 0.384
Loa Loa (eye worm) hypothetical protein 0.0102 0.1024 0.3025
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0087 0.0192
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.001 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.06 0.1321
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Loa Loa (eye worm) sugar transporter 0.003 0.0201 0.0595
Echinococcus multilocularis General substrate transporter 0.018 0.1917 0.4219
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.1232 0.1863
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0041 0.0091
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0644
Echinococcus granulosus chromobox protein 1 0.0073 0.0697 0.1533
Toxoplasma gondii hypothetical protein 0.0015 0.0041 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0096 0.0498
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.045 0.2338
Echinococcus granulosus nAChR subunit 0.0012 0.0004 0.0008
Brugia malayi RNA binding protein 0.0066 0.0621 0.1987
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0551 0.1213
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0318 0.1274
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Plasmodium vivax aspartyl protease, putative 0.0014 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0278 0.1443
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0278 0.0888
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0085 0.0832 0.2663
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0644
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0201 0.0644
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0053 0.0465 0.1489
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0278 0.0888
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0195 0.0625
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.0004 0.0008
Echinococcus granulosus dna polymerase eta 0.002 0.0096 0.0211
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0096 0.0498
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0201 0.0644
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Plasmodium falciparum plasmepsin V 0.0014 0.0024 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0053 0.0465 0.1864
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0398 0.0603
Leishmania major protein kinase, putative 0.0065 0.06 0.3121
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0436 0.1395
Loa Loa (eye worm) hypothetical protein 0.0051 0.0448 0.1322
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0606 0.315
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0398 0.1275
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0041 0.0091
Echinococcus granulosus dnaJ subfamily B 0.0412 0.4544 1
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.1232 0.2711
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0201 0.0595
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0004 0.0011
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0014 0.0024 0.0037
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.001 0.0054
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.001 0.0033
Trypanosoma cruzi hexose transporter, putative 0.003 0.0201 0.1047
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0181 0.1923 0.4233
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0016
Plasmodium vivax hexose transporter 0.021 0.2253 0.2253
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0278 0.1112
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0087 0.0087
Onchocerca volvulus 0.0013 0.0009 0.004
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0053 0.0465 0.1864
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0002 0.0003
Brugia malayi CXXC zinc finger family protein 0.0029 0.0194 0.0621
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.0004 0.0011
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0014 0.0024 0.0072
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0102 0.1024 0.2254
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Brugia malayi hypothetical protein 0.0014 0.0024 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0005
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.006 0.031
Schistosoma mansoni hypothetical protein 0.0412 0.4544 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.002 0.0045
Plasmodium falciparum plasmepsin VIII, putative 0.0014 0.0024 0.0024
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0096 0.0211
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0053 0.0465 0.1864
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0108 0.0239
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0053 0.0465 0.1489
Plasmodium falciparum plasmepsin I 0.0059 0.0536 0.0536
Onchocerca volvulus 0.0036 0.0278 0.1531
Plasmodium vivax aspartyl proteinase, putative 0.0059 0.0536 0.0536
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Toxoplasma gondii sugar transporter ST2 0.003 0.0201 0.0304
Schistosoma mansoni hypothetical protein 0.0023 0.0128 0.0281
Schistosoma mansoni chromobox protein 0.0073 0.0697 0.1533
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0278 0.0611
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0551 0.1213
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0096 0.0211
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.001 0.0054
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0181 0.1923 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0278 0.0611
Brugia malayi Protein cec-1. 0.0012 0.0002 0.0005
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0004 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0046 0.0136
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0004 0.0012
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.026 0.2819 0.9021
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0133 0.0692
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0002 0.0005
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Trichomonas vaginalis esterase, putative 0.0036 0.0278 0.0888
Echinococcus multilocularis carbonic anhydrase 0.0085 0.0832 0.1832
Schistosoma mansoni lipoxygenase 0.0081 0.0792 0.1742
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0053 0.0465 0.1489
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0606 0.315
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0136
Trypanosoma brucei polo-like protein kinase 0.0103 0.1038 0.5395
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0469 0.15
Schistosoma mansoni hypothetical protein 0.021 0.2253 0.4958
Plasmodium falciparum hexose transporter 0.021 0.2253 0.2253
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.0004 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0278 0.0888
Leishmania major cytochrome p450-like protein 0.0053 0.0465 0.242
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0201 0.0644
Onchocerca volvulus 0.0013 0.001 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0465 0.1374
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.006 0.031
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0443
Onchocerca volvulus 0.0014 0.0024 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1232 0.3941
Echinococcus granulosus General substrate transporter 0.018 0.1917 0.4219
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Brugia malayi Cytochrome P450 family protein 0.0053 0.0465 0.1489
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.06 0.1773
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.07 0.3642
Brugia malayi Cytochrome P450 family protein 0.0167 0.1762 0.5638
Echinococcus multilocularis snurportin 1 0.031 0.3386 0.7453
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0053 0.0465 0.1864
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0398 0.0877
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0046 0.0148
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0201 0.1047
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0601 0.0601
Onchocerca volvulus 0.0036 0.0278 0.1531
Brugia malayi beta-lactamase family protein 0.0036 0.0278 0.0888
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.119 0.2619
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0041 0.0091
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0053 0.0465 0.1864
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0041 0.0091
Schistosoma mansoni importin beta-1 0.0029 0.0196 0.043
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0201 0.0806
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0053 0.0465 0.242
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0313 0.0313
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0053 0.0465 0.242
Brugia malayi Doublecortin family protein 0.0019 0.0087 0.0279
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0601 0.0601
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0119 0.038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.045 0.045
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0201 0.0644
Brugia malayi Sugar transporter family protein 0.003 0.0201 0.0644
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.002 0.0045
Trypanosoma cruzi hexose transporter 0.0065 0.0606 0.315
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1804 0.5771
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0318 0.5469
Brugia malayi hypothetical protein 0.003 0.0201 0.0644
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.1843 0.4055
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Echinococcus granulosus cpg binding protein 0.0031 0.0213 0.0469
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus granulosus Chromo domain 0.0012 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0102 0.1024 0.2254
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.0443
Echinococcus multilocularis carbonic anhydrase II 0.0181 0.1923 0.4233
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0002 0.0005
Plasmodium vivax amine transporter, putative 0.0015 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0033
Schistosoma mansoni polycystin 1-related 0.0019 0.0087 0.0192
Schistosoma mansoni hypothetical protein 0.0348 0.3824 0.8417
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Loa Loa (eye worm) beta-lactamase 0.0036 0.0278 0.0819
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0053 0.0465 0.1489
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0582 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0096 0.0283
Toxoplasma gondii facilitative glucose transporter GT1 0.021 0.2253 0.3406
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0278 0.0611
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0106 0.107 0.3158
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.026 0.2819 0.8326
Brugia malayi Eukaryotic aspartyl protease family protein 0.0014 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0029 0.0196 0.0577
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.1232 0.2711
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0411 0.1316
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0096 0.0384
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0133 0.0426
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0041 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Schistosoma mansoni cytochrome P450 0.0053 0.0465 0.1024
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.1523 0.4874
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0053 0.0465 0.1489
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.2497 1
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Trypanosoma brucei glucose transporter 2A 0.0065 0.0606 0.315
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0096 0.0384
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0697 0.2229
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0331 0.183
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Schistosoma mansoni hypothetical protein 0.0053 0.0465 0.1024
Onchocerca volvulus 0.003 0.0201 0.1108
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0053 0.0465 0.242
Onchocerca volvulus 0.0012 0.0004 0.0011
Brugia malayi cytochrome P450 0.0053 0.0465 0.1489
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0085 0.0832 0.2458
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2253 0.4958
Entamoeba histolytica hypothetical protein 0.0024 0.0133 0.1283
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Echinococcus multilocularis 0.0053 0.0465 0.1024
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0053 0.0465 0.1489
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0201 0.0201
Schistosoma mansoni chromobox protein 0.0012 0.0002 0.0004
Brugia malayi major facilitator superfamily protein 0.003 0.0201 0.0644
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0606 0.1939
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.0004 0.0011
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0398 1
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.001 0.003
Onchocerca volvulus 0.0019 0.0087 0.0474
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.002 0.0045
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0053 0.0465 0.1864
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0278 0.0888
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.0004 0.0012
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0201 0.0443
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0041 0.0091
Onchocerca volvulus 0.003 0.0201 0.1108
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0041 0.0041
Brugia malayi MH2 domain containing protein 0.012 0.1231 0.3939
Schistosoma mansoni single-minded 0.0049 0.0422 0.0929
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0606 0.1939
Leishmania major cytochrome p450-like protein 0.0053 0.0465 0.242
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0053 0.0465 0.1864
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.001 0.0033
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0601 0.0908
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.06 0.1321
Schistosoma mansoni ran 0.0021 0.0108 0.0239
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.0004 0.0012
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0096 0.0307
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0181 0.1923 0.6154
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.0004 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Mycobacterium ulcerans hypothetical protein 0.0036 0.0278 0.0888
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0582 0.1861
Leishmania major glucose transporter, lmgt2 0.0065 0.0606 0.315
Echinococcus multilocularis dna polymerase kappa 0.002 0.0096 0.0211
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0016
Onchocerca volvulus 0.0015 0.0041 0.0219
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Brugia malayi hypothetical protein 0.0019 0.0087 0.0279
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0119 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0062
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.021 0.2253 0.4958
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0041 0.0091
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0002 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.0004 0.0008
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.045 0.045
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0053 0.0465 0.1489
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0108 0.0564
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0114 0.1156 0.2545
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0621 0.1367
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0114 0.1156 0.37
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.1523 0.3353
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0398 0.2072
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0053 0.0465 0.1864
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0005 0.0015
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0278 0.1112
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.0004 0.0011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.006 0.031
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0004 0.0008
Leishmania major GTP-binding protein, putative 0.0021 0.0108 0.0564
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trypanosoma brucei sugar transporter, putative 0.003 0.0201 0.1047
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0398 0.1275
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0114 0.1156 0.2545
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0059 0.0536 0.118
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0621 0.1834
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.1232 0.4934
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.006 0.031
Brugia malayi hypothetical protein 0.0164 0.1732 0.5543
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0257
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Onchocerca volvulus 0.0015 0.0041 0.0219
Schistosoma mansoni glucose transport protein 0.021 0.2253 0.4958
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0443
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0606 0.1939
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0096 0.0498
Toxoplasma gondii protein kinase, putative 0.0594 0.6613 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0053 0.0465 0.242
Giardia lamblia Hexose transporter 0.003 0.0201 0.194
Brugia malayi hypothetical protein 0.0019 0.0087 0.0279
Onchocerca volvulus 0.003 0.0201 0.1108
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0101
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0087 0.0192
Brugia malayi Heterochromatin protein 1 0.0073 0.0697 0.2229
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0128 0.0281
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0682
Echinococcus granulosus carbonic anhydrase 0.0085 0.0832 0.1832
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1038 1
Plasmodium falciparum plasmepsin X 0.0014 0.0024 0.0024
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0085 0.0832 0.2663
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.0004 0.0012
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0422 0.0929
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0002 0.0004
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0041 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0046 0.0101
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0108 0.0164
Mycobacterium leprae putative cytochrome p450 0.0053 0.0465 0.7999
Schistosoma mansoni carbonic anhydrase 0.0085 0.0832 0.1832
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.2819 0.9021
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0041 0.0091
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Echinococcus multilocularis chromobox protein 1 0.0073 0.0697 0.1533
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0033
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0053 0.0465 0.1864
Onchocerca volvulus 0.0012 0.0004 0.0011
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.001 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0041 0.0091
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.1232 0.6404
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0398 0.0398
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.0443
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0132
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0536 0.118
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Schistosoma mansoni glucose transport protein 0.021 0.2253 0.4958
Brugia malayi Cation transporter family protein 0.0012 0.0004 0.0012
Brugia malayi glutaminase DH11.1 0.0287 0.3126 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0053 0.0465 0.1489
Onchocerca volvulus 0.003 0.0201 0.1108
Plasmodium vivax importin-beta 2, putative 0.0029 0.0196 0.0196
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0606 0.1939
Onchocerca volvulus 0.0036 0.0278 0.1531
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0101
Toxoplasma gondii sugar transporter ST3 0.003 0.0201 0.0304
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0201 0.0443
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0353 0.0534
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Loa Loa (eye worm) hypothetical protein 0.0059 0.0536 0.1583
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0053 0.0465 0.1864
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.0004 0.0008
Leishmania major glucose transporter, lmgt1 0.0065 0.0606 0.315
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0621 0.1987
Leishmania major carbonic anhydrase-like protein 0.0181 0.1923 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0114 0.1156 0.37
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0465 0.242
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Mycobacterium ulcerans lipase LipD 0.0036 0.0278 0.0888
Schistosoma mansoni carbonic anhydrase-related 0.0085 0.0832 0.1832
Onchocerca volvulus 0.0012 0.0004 0.0011
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0046 0.0101
Echinococcus granulosus carbonic anhydrase II 0.0181 0.1923 0.4233
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0601 0.0601
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0601 0.0601
Plasmodium falciparum plasmepsin VI 0.0059 0.0536 0.0536
Brugia malayi beta-lactamase 0.0036 0.0278 0.0888
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0063 0.0582 0.1718
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0053 0.0465 0.1864
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0195 0.0625
Trypanosoma cruzi glucose transporter, putative 0.003 0.0201 0.1047
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Echinococcus multilocularis cpg binding protein 0.0031 0.0213 0.0469
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0353 0.113
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0096 0.0498
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0443
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0002 0.0005
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0076 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0201 0.0644
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.0004 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0004 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0621 0.1367
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0331 0.106
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0278 0.0611
Schistosoma mansoni hypothetical protein 0.0085 0.0832 0.1832
Schistosoma mansoni protein kinase 0.0065 0.06 0.1321
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0085 0.0832 0.2663
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.1232 0.2711
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0411 0.1214
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0201 1
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0096 0.0307
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0102 0.1024 0.2254
Schistosoma mansoni lipoxygenase 0.0117 0.119 0.2619
Echinococcus granulosus chromobox protein 2 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0278 0.1112
Echinococcus granulosus cytochrome P450 2K1 0.0053 0.0465 0.1024
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.003
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0313 0.3012
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Schistosoma mansoni kinase 0.0054 0.0484 0.1065
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0367 0.1174
Schistosoma mansoni carbonic anhydrase-related 0.0085 0.0832 0.1832
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.031 0.3386 0.7453
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0096 0.0498
Plasmodium vivax plasmepsin V, putative 0.0014 0.0024 0.0024
Brugia malayi Cation transporter family protein 0.0012 0.0004 0.0012
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0016
Onchocerca volvulus 0.0012 0.0004 0.0011
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0443
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1231 0.3636
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0065 0.06 0.1773
Echinococcus granulosus snurportin 1 0.031 0.3386 0.7453
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0102 0.1024 0.2254
Schistosoma mansoni cpg binding protein 0.0031 0.0213 0.0469
Echinococcus multilocularis chromobox protein 1 0.0073 0.0697 0.1533
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0582 0.128
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0196 0.1016
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.045 0.2338
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0201 0.0644
Plasmodium falciparum plasmepsin II 0.0059 0.0536 0.0536
Schistosoma mansoni sodium/chloride dependent transporter 0.002 0.009 0.0199
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0398 0.0877
Echinococcus multilocularis RUN 0.0019 0.0087 0.0192
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0002 0.0004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0606 0.315
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0041 0.0091
Echinococcus multilocularis nAChR subunit 0.0012 0.0004 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0278 0.0888
Loa Loa (eye worm) aspartyl protease 6 0.0014 0.0024 0.0072
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0313 0.3012
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0053 0.0465 0.1489
Leishmania major cytochrome p450-like protein 0.0053 0.0465 0.242
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1908 0.6105
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0465 0.242
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1232 0.3941
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0167 0.1767 0.7077
Schistosoma mansoni sugar transporter 0.003 0.0201 0.0443
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0122
Brugia malayi Pepsin A precursor 0.0014 0.0024 0.0078
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0114 0.1156 0.4632
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0119 0.2978
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.045 0.2338
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0353 0.0353
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.1477 0.325
Brugia malayi hypothetical protein 0.0015 0.0041 0.0132
Schistosoma mansoni nAChR subunit 0.0012 0.0004 0.0008
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0606 0.315
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.002 0.006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0754
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.001 0.0023
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0114 0.1156 0.37
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0087 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1038 0.2284
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0053 0.0465 0.1489
Plasmodium falciparum importin beta, putative 0.0029 0.0196 0.0196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0411 0.0905
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0012 0.0005 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Trichomonas vaginalis hypothetical protein 0.0012 0.0002 0.0005
Onchocerca volvulus 0.0012 0.0004 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1232 0.3941
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0002 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0024 0.0127
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Plasmodium vivax plasmepsin IV, putative 0.0059 0.0536 0.0536
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0002 0.0005
Plasmodium vivax aspartyl proteinase, putative 0.0014 0.0024 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0024 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0053 0.0465 0.1864
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0278 0.0888
Trichomonas vaginalis ran, putative 0.0021 0.0108 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0042 0.0133
Toxoplasma gondii aspartyl protease ASP1 0.0059 0.0536 0.0811
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0108 0.0347
Echinococcus multilocularis Chromo domain 0.0012 0.0002 0.0004
Leishmania major protein kinase, putative 0.0017 0.006 0.031
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0002 0.0003
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0201 0.0443
Onchocerca volvulus 0.003 0.0201 0.1108
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0398 0.0877
Plasmodium vivax CDK-related protein kinase 6, putative 0.0892 1 1
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0562
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0041 0.0132
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.034 0.3726 0.5635
Trypanosoma brucei glucose transporter, putative 0.0065 0.0606 0.315
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0004 0.0008
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0582 0.128
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0278 0.0888
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0053 0.0465 0.1864
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0601 0.0601
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.06 0.1921
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0053 0.0465 0.1489
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0004 0.0008
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.0004 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0041 0.0091
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0278 0.0888
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0012 0.0005 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Mycobacterium ulcerans sugar transporter 0.003 0.0201 0.0644
Brugia malayi PAS domain containing protein 0.0049 0.0422 0.1351
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.07 0.3642
Plasmodium falciparum plasmepsin VII 0.0014 0.0024 0.0024
Giardia lamblia DINP protein human, muc B family 0.002 0.0096 0.0924
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0004 0.0012
Mycobacterium leprae Conserved hypothetical protein 0.0053 0.0465 0.7999
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.0004 0.0008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0108 0.0564
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.07 0.3642
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0278 0.0819
Echinococcus multilocularis chromobox protein 2 0.0012 0.0002 0.0004
Schistosoma mansoni rab6-interacting 0.0019 0.0087 0.0192
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0108 0.0108
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0096 0.0498
Brugia malayi Cam kinase protein 1 0.0065 0.06 0.1921
Leishmania major protein kinase, putative 0.0017 0.006 0.031
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0053 0.0465 0.1864
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Loa Loa (eye worm) acetyltransferase 0.0146 0.1523 0.4499
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0128 0.0281
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.06 0.1921
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.07 0.3642
Onchocerca volvulus 0.003 0.0201 0.1108
Onchocerca volvulus 0.0029 0.0194 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0331 0.106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0036 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0004 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0004 0.0008
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0278 0.1112
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.0004 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0465 0.1489
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0096 0.0498
Loa Loa (eye worm) hypothetical protein 0.0164 0.1732 0.5116
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0041 0.0132
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.0595
Echinococcus granulosus solute carrier family 22 0.003 0.0201 0.0443
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0411 0.0905
Treponema pallidum sodium- and chloride- dependent transporter 0.0015 0.0041 0.3469
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0053 0.0465 0.1489
Loa Loa (eye worm) hypothetical protein 0.0036 0.0278 0.0819
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0041 0.0091
Leishmania major DNA polymerase kappa, putative 0.002 0.0096 0.0498
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1038 0.332
Plasmodium vivax sugar transporter, putative 0.003 0.0201 0.0201
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.045 0.068
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0053 0.0465 0.1864
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0053 0.0465 0.1864
Brugia malayi TAR-binding protein 0.0066 0.0621 0.1987
Echinococcus multilocularis carbonic anhydrase 0.0085 0.0832 0.1832
Echinococcus granulosus RUN 0.0019 0.0087 0.0192
Echinococcus multilocularis geminin 0.0348 0.3824 0.8417
Loa Loa (eye worm) hypothetical protein 0.0041 0.0331 0.0979
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1038 0.332
Leishmania major DNA polymerase eta, putative 0.002 0.0096 0.0498
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0011
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0436 0.1287
Plasmodium falciparum proline--tRNA ligase 0.0073 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0085 0.0832 0.2458
Trichomonas vaginalis sugar transporter, putative 0.003 0.0201 0.0644
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0582 0.5606
Brugia malayi follicle stimulating hormone receptor 0.0229 0.2467 0.7892
Echinococcus multilocularis solute carrier family 22 0.003 0.0201 0.0443
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0411 0.0905
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.07 0.3642
Trypanosoma cruzi sugar transporter, putative 0.003 0.0201 0.1047
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0606 0.315
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0201 0.0443
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0194 0.0573
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0278 0.1443
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0096 0.0498

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1200 nM Inhibition of human recombinant renin using fluorescence-quenched RE(EDANS)IHPFHLVIHTK(Dabcyl)R substrate by fluorimetric assay ChEMBL. 25050166
IC50 (binding) = 15200 nM Inhibition of human recombinant renin in presence of human plasma using Ac- IHPFHL-VIHNK-(DY-505-X5)-COOH substrate by fluorimetric assay ChEMBL. 25050166

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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