Detailed information for compound 1138318

Basic information

Technical information
  • TDR Targets ID: 1138318
  • Name: S-[2-[[3-azido-5-(5-methyl-2,4-dioxopyrimidin -1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]o xyethyl] ethanethioate
  • MW: 449.376 | Formula: C14H20N5O8PS
  • H donors: 2 H acceptors: 5 LogP: -0.08 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: [N-]=[N+]=NC1CC(OC1COP(=O)(OCCSC(=O)C)O)n1cc(C)c(=O)[nH]c1=O
  • InChi: 1S/C14H20N5O8PS/c1-8-6-19(14(22)16-13(8)21)12-5-10(17-18-15)11(27-12)7-26-28(23,24)25-3-4-29-9(2)20/h6,10-12H,3-5,7H2,1-2H3,(H,23,24)(H,16,21,22)
  • InChiKey: BKOJYRVDGGNYQZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • S-[2-[[3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyethyl] ethanethioate
  • ethanethioic acid S-[2-[[3-azido-5-(5-methyl-2,4-dioxo-1-pyrimidinyl)-2-tetrahydrofuranyl]methoxy-hydroxyphosphoryl]oxyethyl] ester
  • ethanethioic acid S-[2-[[3-azido-5-(2,4-diketo-5-methyl-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyethyl] ester
  • S-[2-[[3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxyethyl] ethanethioate
  • 2',3'-Dideoxy-3'-azidothymidin-5'-yl, S-acetyl-2-thioethyl, phosphate
  • AIDS-020974
  • AIDS020974
  • SATE-AZTMP

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0141 0.0416
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.1344 0.2406
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0224 0.1298
Echinococcus granulosus adenylate cyclase 9 0.0078 0.0359 0.0644
Loa Loa (eye worm) hypothetical protein 0.0041 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0056 0.0184
Onchocerca volvulus 0.0023 0.0056 0.008
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0019 0.0011
Brugia malayi beta-lactamase family protein 0.0035 0.0123 0.0116
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0035 0.0082
Brugia malayi G protein-coupled receptor F59B2.13 0.0456 0.2456 0.245
Loa Loa (eye worm) G-protein coupled receptor 0.0456 0.2456 0.2456
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0035 0.0062
Mycobacterium tuberculosis Conserved protein 0.0035 0.0123 0.0904
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0123 0.1264
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0056 0.0326
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0013 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0471 0.146
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0134 0.067 0.2089
Schistosoma mansoni hypothetical protein 0.0029 0.0087 0.0248
Brugia malayi mbt repeat family protein 0.0094 0.0446 0.0439
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0103 0.1351
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0035 0.0146
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.0446 0.0446
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0035 0.0027
Brugia malayi Cytochrome P450 family protein 0.0036 0.0128 0.012
Loa Loa (eye worm) neuropeptide F receptor 0.0456 0.2456 0.2456
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0518 0.1609
Brugia malayi Smad1 0.0026 0.0073 0.0065
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0056 0.0655
Mycobacterium ulcerans beta-lactamase 0.0035 0.0123 0.1264
Plasmodium falciparum phd finger protein, putative 0.0029 0.0087 0.647
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0162 0.0825 0.0819
Trypanosoma brucei protein kinase, putative 0.0107 0.0519 0.3113
Loa Loa (eye worm) MBCTL1 0.0107 0.0518 0.0518
Loa Loa (eye worm) beta-lactamase 0.0035 0.0123 0.0123
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0578 0.3438
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0123 0.0904
Brugia malayi hypothetical protein 0.0225 0.1174 0.1168
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0171 0.0975
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0141 0.0706 0.0706
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0019 0.0011
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0446 0.1382
Onchocerca volvulus 0.0456 0.2456 0.4581
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0037
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0456 0.2456 0.2764
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0456 0.2456 0.245
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0171 0.0975
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0134 0.067 0.2089
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0196 0.0591
Brugia malayi G-protein coupled receptor 0.0456 0.2456 0.245
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0519 0.0584
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0456 0.2456 0.4396
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0211 0.0237
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0134 0.067 0.2089
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi Protein kinase domain containing protein 0.0018 0.0025 0.0018
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.0446 0.1382
Echinococcus multilocularis chromobox protein 1 0.0069 0.0311 0.035
Brugia malayi isocitrate dehydrogenase 0.0035 0.0122 0.0115
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus granulosus cpg binding protein 0.0032 0.0102 0.0183
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0083 0.0083
Schistosoma mansoni biogenic amine (5HT) receptor 0.0456 0.2456 0.7735
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.0446 0.0799
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0706 0.2205
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0456 0.2456 0.2764
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0456 0.2456 0.2764
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0076 0.0136
Echinococcus granulosus g protein coupled receptor 0.0456 0.2456 0.4396
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0075 0.0341 0.0616
Brugia malayi Pre-SET motif family protein 0.0124 0.0612 0.0606
Brugia malayi Adenylyl cyclase protein 0.0078 0.0359 0.0352
Echinococcus multilocularis G-protein coupled receptor, putative 0.0456 0.2456 0.2764
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.0446 0.0799
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0158 0.0285
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0283 0.0867
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0519 0.0929
Echinococcus multilocularis dro:myosuppressin receptor 0.0456 0.2456 0.2764
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0019 0.0011
Brugia malayi jmjC domain containing protein 0.0095 0.0453 0.0446
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0578 0.1072
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0019 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0019 0.0011
Schistosoma mansoni single-minded 0.0049 0.0199 0.0601
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0057
Schistosoma mansoni loxhd1 0.002 0.0035 0.0082
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0122 0.0729
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1212 0.1364
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0076 0.0213
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0035 0.1164
Echinococcus multilocularis RUN 0.002 0.0035 0.0039
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0035 0.019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0456 0.2456 0.2764
Loa Loa (eye worm) hypothetical protein 0.0051 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.007 0.0316 0.0316
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.0749 0.4468
Schistosoma mansoni neuropeptide receptor 0.0456 0.2456 0.7735
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0103 0.1409
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0519 0.1612
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0518 0.0511
Schistosoma mansoni transcription factor LCR-F1 0.0225 0.1174 0.3684
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0272 0.3081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0057
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0232 0.1212 0.1212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1212 0.3801
Schistosoma mansoni hypothetical protein 0.002 0.0035 0.0082
Onchocerca volvulus 0.0456 0.2456 0.4581
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.006 0.0161
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.005 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0456 0.2456 0.2764
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0123 0.0219
Brugia malayi Serotonin receptor 0.0456 0.2456 0.245
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.0122 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0272 0.3081
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0374 0.2001 0.6297
Schistosoma mansoni neuropeptide receptor 0.0456 0.2456 0.7735
Schistosoma mansoni amine GPCR 0.0456 0.2456 0.7735
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0519 0.8421
Echinococcus granulosus neuropeptide Y receptor 0.0456 0.2456 0.4396
Schistosoma mansoni amine GPCR 0.0456 0.2456 0.7735
Echinococcus multilocularis protein patched 0.0041 0.0157 0.0176
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0056 0.0184
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0035
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0078 0.0359 0.065
Brugia malayi neuropeptide F receptor 0.0456 0.2456 0.245
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0578 0.0578
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0122 0.1742
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Brugia malayi beta-lactamase family protein 0.0035 0.0123 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0456 0.2456 0.2764
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0024 0.0024
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0019 0.0011
Onchocerca volvulus 0.0456 0.2456 0.4581
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0019 0.0107
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0103 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Mycobacterium leprae Probable lipase LipE 0.0035 0.0123 0.186
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0347 0.0347
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0518 0.0927
Echinococcus multilocularis 0.0017 0.0019 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0347 0.107
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi hypothetical protein 0.0165 0.0841 0.0834
Loa Loa (eye worm) cytochrome P450 0.0017 0.0019 0.0019
Schistosoma mansoni intermediate filament proteins 0.0056 0.0239 0.0728
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0456 0.2456 0.2456
Brugia malayi MH1 domain containing protein 0.0026 0.0073 0.0065
Echinococcus multilocularis g protein coupled receptor 0.0456 0.2456 0.2764
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0012
Brugia malayi TAR-binding protein 0.0076 0.0347 0.034
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0456 0.2456 0.2764
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.0152
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0035 0.0152
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0456 0.2456 0.4396
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0347 0.107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0211 0.0237
Echinococcus multilocularis cpg binding protein 0.0032 0.0102 0.0115
Loa Loa (eye worm) transcription factor SMAD2 0.0386 0.2069 0.2069
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0456 0.2456 0.2764
Brugia malayi hypothetical protein 0.002 0.0035 0.0028
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0456 0.2456 0.7735
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0023
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0076 0.0132
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0073 0.013
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0073 0.0082
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0456 0.2456 0.7735
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0032
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0103 0.1351
Schistosoma mansoni opsin-like receptor 0.0456 0.2456 0.7735
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.012 0.0591 0.0665
Schistosoma mansoni hypothetical protein 0.0456 0.2456 0.7735
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0056 0.0048
Loa Loa (eye worm) nuclear factor I 0.0015 0.0007 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0056 0.0446
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.0151
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0103 0.8012
Entamoeba histolytica hypothetical protein 0.0225 0.1174 1
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0224 0.0408
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0087 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus granulosus g-protein coupled receptor 0.0456 0.2456 0.4396
Onchocerca volvulus 0.0456 0.2456 0.4581
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0612 0.0689
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.0842 0.7079
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0519 0.0961
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0035 0.0202
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0266 0.1591
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0211 0.0204
Echinococcus granulosus allatostatin A receptor 0.0456 0.2456 0.4396
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0019 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0142 0.0255
Onchocerca volvulus 0.0456 0.2456 0.4581
Loa Loa (eye worm) hypothetical protein 0.0075 0.0341 0.0341
Echinococcus multilocularis neuropeptides capa receptor 0.0456 0.2456 0.2764
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0035 0.0039
Schistosoma mansoni hypothetical protein 0.004 0.0148 0.0441
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0035 0.0062
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Echinococcus granulosus dna polymerase kappa 0.0019 0.0035 0.0062
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0035 0.0122 0.0729
Schistosoma mansoni netrin receptor unc5 0.0016 0.0013 0.0012
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0456 0.2456 0.7735
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0042 0.0158 0.0895
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0023 0.0049
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0347 0.0391
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0035 0.0054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0456 0.2456 0.7735
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.006 0.0107
Mycobacterium ulcerans lipase LipD 0.0035 0.0123 0.1264
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0369 0.1974 0.2222
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0019 0.0011
Echinococcus granulosus peregrin 0.0031 0.01 0.018
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0211 0.0204
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0057
Schistosoma mansoni cytochrome P450 0.0017 0.0019 0.0032
Echinococcus granulosus smad 0.0026 0.0073 0.013
Brugia malayi PAS domain containing protein 0.0049 0.0199 0.0192
Entamoeba histolytica hypothetical protein 0.0225 0.1174 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0122 0.0138
Echinococcus multilocularis neuropeptide receptor 0.0456 0.2456 0.2764
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0578 0.4769
Loa Loa (eye worm) nuclear hormone receptor 0.0113 0.0555 0.0555
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0019 0.0011
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0094 0.0446 0.0446
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0519 0.3078
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Echinococcus multilocularis musashi 0.0056 0.0239 0.0269
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0078 0.0359 0.065
Schistosoma mansoni hypothetical protein 0.0021 0.004 0.0099
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Echinococcus multilocularis rho associated protein kinase 0.0585 0.3173 0.3571
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0157 0.0157
Echinococcus granulosus neuropeptide FF receptor 2 0.0456 0.2456 0.4396
Echinococcus multilocularis Eukaryotic translation initiation factor 4H 0.0134 0.067 0.0754
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0584 0.1045
Echinococcus multilocularis Smad4 0.0026 0.0073 0.0082
Brugia malayi Heterochromatin protein 1 0.0069 0.0311 0.0304
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0675 0.2106
Echinococcus granulosus chromobox protein 1 0.0069 0.0311 0.0556
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0519 0.3078
Brugia malayi Bromodomain containing protein 0.0076 0.0349 0.0342
Echinococcus multilocularis G protein coupled receptor 139 0.0456 0.2456 0.2764
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0122 0.0682
Schistosoma mansoni chromobox protein 0.0069 0.0311 0.0954
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0519 0.0929
Schistosoma mansoni DNA polymerase eta 0.0019 0.0035 0.0082
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0056 0.0655
Onchocerca volvulus 0.0585 0.3173 0.5925
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0693 0.078
Onchocerca volvulus 0.0094 0.0446 0.0813
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Echinococcus granulosus jumonji domain containing protein 0.004 0.015 0.0269
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0076 0.0132
Loa Loa (eye worm) G-protein coupled receptor 0.0456 0.2456 0.2456
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0087 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0456 0.2456 0.2764
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0035 0.0039
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0369 0.1974 0.3534
Brugia malayi CXXC zinc finger family protein 0.0028 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0038 0.0138 0.0138
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0456 0.2456 0.7735
Echinococcus granulosus Solute carrier family 22 5 0.102 0.5586 1
Brugia malayi ORL1-like opioid receptor 0.0456 0.2456 0.245
Echinococcus multilocularis g protein coupled receptor 0.0456 0.2456 0.2764
Entamoeba histolytica hypothetical protein 0.0225 0.1174 1
Brugia malayi MH2 domain containing protein 0.0386 0.2069 0.2064
Schistosoma mansoni hypothetical protein 0.0456 0.2456 0.7735
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0019 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus multilocularis tumor protein p63 0.0332 0.1766 0.1988
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0519 0.0961
Schistosoma mansoni hypothetical protein 0.004 0.0148 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0035 0.0054
Loa Loa (eye worm) neuropeptide F receptor 0.0456 0.2456 0.2456
Brugia malayi phosphofructokinase 0.0117 0.0578 0.0571
Echinococcus multilocularis sex peptide receptor 0.0456 0.2456 0.2764
Brugia malayi MH1 domain containing protein 0.0026 0.0073 0.0065
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.077 0.077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0056 0.0326
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0311 0.0571
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0224 0.0408
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0272 0.3081
Echinococcus granulosus death domain containing protein 0.0016 0.0013 0.0023
Schistosoma mansoni hypothetical protein 0.0051 0.0211 0.0639
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0057
Brugia malayi mbt repeat family protein 0.0094 0.0446 0.0439
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0239 0.0232
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0123 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0266 0.0486
Onchocerca volvulus 0.0049 0.0196 0.0343
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0123 0.0219
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Schistosoma mansoni adenoreceptor 0.0456 0.2456 0.7735
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0103 0.1409
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0035 0.0201
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.0446 0.0813
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0261 0.4077
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0016 0.0019
Echinococcus granulosus hypothetical protein 0.0456 0.2456 0.4396
Leishmania major hypothetical protein, conserved 0.0035 0.0123 0.0686
Echinococcus granulosus biogenic amine 5HT receptor 0.0456 0.2456 0.4396
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0266 0.0299
Leishmania major DNA polymerase kappa, putative 0.0019 0.0035 0.0152
Mycobacterium ulcerans hypothetical protein 0.0023 0.0056 0.0446
Loa Loa (eye worm) adenylyl cyclase 3 0.0184 0.0949 0.0949
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0128 0.0128
Echinococcus granulosus tm gpcr rhodopsin 0.0456 0.2456 0.4396
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0578 0.1072
Brugia malayi PHD-finger family protein 0.0026 0.0073 0.0066
Onchocerca volvulus 0.0456 0.2456 0.4581
Schistosoma mansoni opsin-like receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis allatostatin A receptor 0.0456 0.2456 0.2764
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.0122 0.0138
Echinococcus granulosus serotonin receptor 0.0456 0.2456 0.4396
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0025 0.0036
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0103 0.8012
Brugia malayi chromobox protein homolog 3 0.0039 0.0142 0.0135
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.1344 0.1513
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi Isocitrate dehydrogenase 0.0035 0.0122 0.0115
Loa Loa (eye worm) hypothetical protein 0.0039 0.0142 0.0142
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0141 0.0416
Onchocerca volvulus 0.0056 0.0239 0.0425
Schistosoma mansoni lamin 0.0056 0.0239 0.0728
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0202
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0456 0.2456 0.2456
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0224 0.0408
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0073 0.0201
Loa Loa (eye worm) hypothetical protein 0.0097 0.0463 0.0463
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0035 0.0122 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0016 0.0019
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0858 0.4688 0.4688
Brugia malayi Steroid receptor seven-up type 2 0.012 0.0591 0.0584
Echinococcus granulosus histone lysine methyltransferase setb 0.0141 0.0706 0.1265
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.023 0.0259
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0021 0.0037
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0142 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0123 0.0686
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0123 0.0219
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0456 0.2456 0.245
Onchocerca volvulus 0.0456 0.2456 0.4581
Brugia malayi Tachykinin-like peptides receptor 99D 0.0456 0.2456 0.245
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0056 0.0446
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1212 0.3801
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0266 0.1548
Schistosoma mansoni myosin xvIII 0.0456 0.2456 0.7735
Brugia malayi RNA binding protein 0.0076 0.0347 0.034
Schistosoma mansoni rab6-interacting 0.002 0.0035 0.0082
Brugia malayi 6-phosphofructokinase 0.0117 0.0578 0.0571
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0578 0.0651
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0463 0.3754
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0456 0.2456 0.4396
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0016 0.0019
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0158 0.0273
Brugia malayi cytochrome P450 0.0017 0.0019 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0706 0.2205
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0123 0.0904
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0518 0.0583
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0122 0.0682
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0019 0.0057
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0519 0.0519
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0123 0.022
Onchocerca volvulus 0.0078 0.0359 0.065
Onchocerca volvulus 0.0456 0.2456 0.4581
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Schistosoma mansoni lamin 0.0056 0.0239 0.0728
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0073 0.0082
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0073 0.0073
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0122 0.1742
Onchocerca volvulus 0.0456 0.2456 0.4581
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0141 0.0252
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0456 0.2456 0.2764
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0035 0.0122 0.0899
Brugia malayi RNA binding protein 0.0134 0.067 0.0663
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Giardia lamblia PHD finger protein 15 0.0029 0.0087 0.1087
Echinococcus granulosus zinc finger protein 0.0021 0.0043 0.0078
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0578 0.4816
Echinococcus granulosus neuropeptide receptor 0.0456 0.2456 0.4396
Schistosoma mansoni bromodomain containing protein 0.0064 0.0284 0.0871
Loa Loa (eye worm) TYRA-2 protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.0078 0.0359 0.0359
Echinococcus granulosus g protein coupled receptor 0.0456 0.2456 0.4396
Echinococcus granulosus chromobox protein 1 0.0069 0.0311 0.0556
Echinococcus multilocularis fmrfamide receptor 0.0456 0.2456 0.2764
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0456 0.2456 0.2456
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.2456 0.2764
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0019 0.0011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0094 0.0094
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0076 0.0069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0076 0.0132
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0157 0.028
Brugia malayi MAP kinase sur-1 0.0107 0.0519 0.0512
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0272 0.2188
Onchocerca volvulus Neuropeptide F receptor homolog 0.0456 0.2456 0.4581
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0035 0.0191
Echinococcus multilocularis chromobox protein 1 0.0069 0.0311 0.035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.0152
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0055 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.0056
Echinococcus multilocularis dna polymerase eta 0.0019 0.0035 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1212 0.2169
Echinococcus granulosus neuropeptides capa receptor 0.0456 0.2456 0.4396
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0016 0.0019
Echinococcus granulosus dna polymerase eta 0.0019 0.0035 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0023
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Schistosoma mansoni biogenic amine (5HT) receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis zinc finger protein 0.0021 0.0043 0.0049
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0094 0.0087
Loa Loa (eye worm) hypothetical protein 0.0134 0.067 0.067
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0035 0.0122 0.1686
Echinococcus granulosus lamin dm0 0.0056 0.0239 0.0428
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus granulosus tar DNA binding protein 0.0076 0.0347 0.0622
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0123 0.0138
Onchocerca volvulus 0.0456 0.2456 0.4581
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0035
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0123 0.1264
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0456 0.2456 0.2764
Brugia malayi Calcitonin receptor-like protein seb-1 0.0162 0.0825 0.0819
Mycobacterium ulcerans hypothetical protein 0.0035 0.0123 0.1264
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0062 0.0055
Onchocerca volvulus 0.002 0.0035 0.0041
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0313 0.1664 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Leishmania major DNA polymerase eta, putative 0.0019 0.0035 0.0152
Schistosoma mansoni patched 1 0.0041 0.0157 0.0467
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.012 0.0591 0.1057
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0272 0.0833
Echinococcus multilocularis somatostatin receptor 0.0456 0.2456 0.2764
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Toxoplasma gondii ABC1 family protein 0.0035 0.0123 0.1752
Onchocerca volvulus 0.0456 0.2456 0.4581
Brugia malayi CHE-14 protein 0.0041 0.0157 0.0149
Onchocerca volvulus 0.0456 0.2456 0.4581
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0077 0.0087
Loa Loa (eye worm) melatonin receptor type 1A 0.0456 0.2456 0.2456
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0266 0.0475
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0456 0.2456 0.4396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0087 0.1151
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0125 0.0223
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0518 0.0927
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0035 0.019
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0456 0.2456 0.2764
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0157 0.028
Echinococcus granulosus GPCR family 2 0.0051 0.0211 0.0378
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0019 0.0019
Schistosoma mansoni biogenic amine receptor 0.0456 0.2456 0.7735
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0042 0.0158 0.0284
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0107 0.0518 0.0518
Echinococcus multilocularis g protein coupled receptor 0.0456 0.2456 0.2764
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.2456 0.4396
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Echinococcus granulosus intermediate filament protein 0.0056 0.0239 0.0428
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0456 0.2456 0.2456
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0239 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0019 0.0011
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0519 0.3078
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0265 0.0474
Echinococcus granulosus neuropeptide s receptor 0.0456 0.2456 0.4396
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0043 0.0108
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0578 0.1035
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0519 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0123 0.0904
Loa Loa (eye worm) hypothetical protein 0.0162 0.0825 0.0825
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Brugia malayi SET domain containing protein 0.0016 0.0018 0.0011
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0035 0.0039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0456 0.2456 0.7735
Schistosoma mansoni lipoxygenase 0.002 0.0035 0.0082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0456 0.2456 0.2764
Echinococcus granulosus fmrfamide receptor 0.0456 0.2456 0.4396
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0347 0.107
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Onchocerca volvulus 0.0056 0.0239 0.0425
Schistosoma mansoni hypothetical protein 0.0051 0.0211 0.0639
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0035 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0035 0.0196
Echinococcus granulosus g protein coupled receptor 0.0456 0.2456 0.4396
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0123 0.1696
Echinococcus granulosus rho-associated protein kinase 1 0.0585 0.3173 0.568
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0266 0.1548
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0009 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0056 0.0184
Schistosoma mansoni lipoxygenase 0.0055 0.023 0.0698
Onchocerca volvulus 0.003 0.0095 0.0155
Trypanosoma brucei unspecified product 0.0019 0.0035 0.0202
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.0122 0.0682
Loa Loa (eye worm) hypothetical protein 0.0027 0.0077 0.0077
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0009 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.0056
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0311 0.0311
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0266 0.1548
Brugia malayi Death domain containing protein 0.0016 0.0013 0.0005
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.0122 0.0138
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0368 0.0414
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Onchocerca volvulus 0.0977 0.5346 1
Echinococcus multilocularis neuropeptide receptor 0.0456 0.2456 0.2764
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0035 0.0152
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0578 0.3438
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0158 0.0285
Echinococcus multilocularis adenylate cyclase 9 0.0078 0.0359 0.0405
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0123 0.0123
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0519 0.0584
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0087 0.0248
Schistosoma mansoni polycystin 1-related 0.002 0.0035 0.0082
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0042 0.0158 0.0284
Echinococcus granulosus neuropeptide Y receptor 0.0456 0.2456 0.4396
Onchocerca volvulus 0.0036 0.0128 0.0217
Onchocerca volvulus 0.0456 0.2456 0.4581
Onchocerca volvulus 0.0028 0.0083 0.0132
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Schistosoma mansoni neuropeptide F-like receptor 0.0456 0.2456 0.7735
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Trypanosoma brucei ISWI complex protein 0.0015 0.0011 0.0059
Brugia malayi hypoxia-induced factor 1 0.0152 0.077 0.0763
Echinococcus granulosus tm gpcr rhodopsin 0.0456 0.2456 0.4396
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0122 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0056 0.0446
Schistosoma mansoni hypothetical protein 0.0016 0.0013 0.0012
Echinococcus granulosus G protein coupled receptor 139 0.0456 0.2456 0.4396
Mycobacterium ulcerans hypothetical protein 0.0165 0.0842 1
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0128 0.0144
Schistosoma mansoni cpg binding protein 0.0032 0.0102 0.0295
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0076 0.0069
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0239 0.0239
Brugia malayi larval opioid receptor 0.0456 0.2456 0.245
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0123 0.0361
Brugia malayi Dopamine receptor protein 2 0.0456 0.2456 0.245
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0019 0.0019
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0016 0.0019
Leishmania major hypothetical protein, conserved 0.0015 0.0011 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0087 0.1151
Schistosoma mansoni survival motor neuron protein 0.0052 0.0216 0.0654
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.1181 1
Echinococcus granulosus sex peptide receptor 0.0456 0.2456 0.4396
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0006
Onchocerca volvulus 0.0035 0.0123 0.0207
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0456 0.2456 0.4396
Echinococcus granulosus expressed conserved protein 0.0091 0.043 0.077
Echinococcus granulosus peptide allatostatin:somatostatin 0.0456 0.2456 0.4396
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0019 0.0011
Schistosoma mansoni smad1 5 8 and 0.0026 0.0073 0.0201
Echinococcus multilocularis neuropeptide Y receptor 0.0456 0.2456 0.2764
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0225 0.1174 0.2102
Echinococcus granulosus tm gpcr rhodopsin 0.0456 0.2456 0.4396
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0456 0.2456 0.245
Brugia malayi 6-phosphofructokinase 0.0117 0.0578 0.0571
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0148 0.0749 0.4496
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0087 0.1091
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0456 0.2456 0.7735
Schistosoma mansoni growth hormone secretagogue receptor 0.0456 0.2456 0.7735
Onchocerca volvulus Alhambra homolog 0.0029 0.0087 0.014
Loa Loa (eye worm) doublecortin family protein 0.002 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Schistosoma mansoni neuropeptide receptor 0.0456 0.2456 0.7735
Brugia malayi Dopamine receptor protein 1 0.0456 0.2456 0.245
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0035 0.019
Schistosoma mansoni hypothetical protein 0.0225 0.1174 0.3684
Echinococcus granulosus RUN 0.002 0.0035 0.0062
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0578 0.18
Brugia malayi G protein-coupled receptor 0.0456 0.2456 0.245
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0072
Plasmodium vivax SET domain protein, putative 0.0124 0.0612 1
Schistosoma mansoni serine/threonine protein kinase 0.0585 0.3173 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0386 0.2069 0.2069
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0345 0.1062
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0463 0.0828
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Loa Loa (eye worm) hypothetical protein 0.0114 0.0559 0.0559
Schistosoma mansoni amine GPCR 0.0456 0.2456 0.7735
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0107
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0265 0.0298
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Onchocerca volvulus 0.0135 0.0675 0.1242
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0103 1
Echinococcus multilocularis jumonji domain containing protein 0.004 0.015 0.0169
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.2456 0.2764
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0035 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0056 0.0048
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0121 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0079 0.0137
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0123 0.0116
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0311 0.0571
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0211 0.0211
Echinococcus multilocularis expressed conserved protein 0.0091 0.043 0.0484
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0456 0.2456 0.4581
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0023
Schistosoma mansoni amine GPCR 0.0456 0.2456 0.7735
Toxoplasma gondii hypothetical protein 0.005 0.0207 0.3164
Brugia malayi PHD-finger family protein 0.0029 0.0087 0.008
Echinococcus multilocularis smad 0.0026 0.0073 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0578 0.0578
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.0152
Schistosoma mansoni histamine h1 receptor 0.0456 0.2456 0.7735
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0123 0.186
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0142 0.0255
Echinococcus multilocularis lamin 0.0056 0.0239 0.0269
Brugia malayi hypothetical protein 0.002 0.0035 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0519 0.3078
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0035 0.1192
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0456 0.2456 0.2764
Schistosoma mansoni cpg binding protein 0.0032 0.0102 0.0295
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0456 0.2456 0.7735
Echinococcus granulosus single minded 2 0.0036 0.0128 0.023
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0313 0.1664 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0313 0.1664 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus granulosus Smad4 0.0026 0.0073 0.013
Brugia malayi G-protein coupled receptor 0.0456 0.2456 0.245
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Toxoplasma gondii hypothetical protein 0.0019 0.0035 0.0263
Brugia malayi intermediate filament protein 0.0056 0.0239 0.0232
Brugia malayi beta-lactamase 0.0035 0.0123 0.0116
Echinococcus granulosus alpha 1A adrenergic receptor 0.0456 0.2456 0.4396
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Echinococcus multilocularis peregrin 0.0031 0.01 0.0113
Schistosoma mansoni smad1 5 8 and 0.0026 0.0073 0.0201
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0368 0.0659
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0225 0.1174 0.1322
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0035 0.0145
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0199 0.0601
Schistosoma mansoni Smad4 0.0026 0.0073 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0019 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0025 0.0036
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0578 0.4769
Schistosoma mansoni hypothetical protein 0.004 0.0148 0.0441
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0612 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0347 0.107
Echinococcus multilocularis serotonin receptor 0.0456 0.2456 0.2764
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0012
Leishmania major mitochondrial DNA polymerase beta 0.0313 0.1664 1
Onchocerca volvulus 0.0035 0.0123 0.0207
Loa Loa (eye worm) hypothetical protein 0.0044 0.0171 0.0171
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus granulosus adenylate cyclase type IX 0.011 0.0535 0.0957
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Brugia malayi Melatonin receptor type 1A 0.0456 0.2456 0.245
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0578 0.0578
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1212 0.2169
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi AKH receptor 0.0456 0.2456 0.245
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0693 0.124
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0578 1
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.0446 0.0502
Schistosoma mansoni hypothetical protein 0.004 0.0148 0.0441
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0077 0.0139
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0128 0.0121
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0123 0.0219
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.0446 0.0502
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0035 0.0146
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0035 0.0191
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0123 0.0733
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0463 0.0521
Brugia malayi Pre-SET motif family protein 0.0858 0.4688 0.4684
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0211 0.0378
Onchocerca volvulus 0.002 0.0035 0.0041
Trichomonas vaginalis set domain proteins, putative 0.0977 0.5345 1
Brugia malayi RE15519p 0.0456 0.2456 0.245
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Loa Loa (eye worm) RNA binding protein 0.0076 0.0347 0.0347
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0013 0.0013
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0272 0.0488
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0103 0.1409
Echinococcus multilocularis Ankyrin 0.0016 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Brugia malayi putative neuropeptide receptor NPR1 0.0456 0.2456 0.245
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0519 0.0961
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0157 0.0282
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0056 0.0446
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0157 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.0056
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0019 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0123 0.0904
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0578 0.18
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0023
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0519 0.3078
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0035 0.0039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0125 0.014
Schistosoma mansoni biogenic amine receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0453 0.051
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0141 0.0706 0.0795
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0051 0.0211 0.0211
Schistosoma mansoni biogenic amine receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis orexin receptor type 2 0.0456 0.2456 0.2764
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0128 0.1329
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0035 0.0062
Schistosoma mansoni amine GPCR 0.0456 0.2456 0.7735
Brugia malayi MH2 domain containing protein 0.0026 0.0073 0.0065
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus granulosus orexin receptor type 2 0.0456 0.2456 0.4396
Echinococcus granulosus tumor protein p63 0.0332 0.1766 0.3162
Echinococcus granulosus geminin 0.0374 0.2001 0.3583
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0518 0.0583
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0103 0.1404
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0079 0.0137
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0578 0.3471
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0123 0.0904
Brugia malayi hypothetical protein 0.0132 0.0656 0.0649
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0035 0.0279
Loa Loa (eye worm) hypothetical protein 0.0049 0.0196 0.0196
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0519 0.3078
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.004 0.004
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0035 0.0263
Loa Loa (eye worm) hypothetical protein 0.0111 0.0541 0.0541
Echinococcus multilocularis lamin dm0 0.0056 0.0239 0.0269
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0056 0.0446
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0256 0.1344 0.1344
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0037
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0456 0.2456 0.245
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0171 0.0975
Loa Loa (eye worm) hypothetical protein 0.0056 0.0239 0.0239
Mycobacterium tuberculosis Conserved protein 0.0035 0.0123 0.0904
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0019 0.0011
Toxoplasma gondii hypothetical protein 0.0054 0.0224 0.3453
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0035 0.0039
Onchocerca volvulus 0.0052 0.0216 0.0381
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0095
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0266 0.1591
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0087
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0216 0.0209
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0612 0.1908
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0578 0.1072
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.0749 0.4468
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0141 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1212 0.3801
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0103 1
Echinococcus multilocularis GPCR, family 2 0.0051 0.0211 0.0237
Brugia malayi Doublecortin family protein 0.002 0.0035 0.0028
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0019 0.0057
Echinococcus granulosus dro:myosuppressin receptor 0.0456 0.2456 0.4396
Echinococcus granulosus Ankyrin 0.0016 0.0013 0.0024
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0019 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Onchocerca volvulus 0.0456 0.2456 0.4581
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0456 0.2456 0.7735
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0061 0.0266 0.0811
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0347 0.107
Schistosoma mansoni hypothetical protein 0.0569 0.3085 0.9723
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0076 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0103 0.0181
Onchocerca volvulus 0.0456 0.2456 0.4581
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0272 0.0833
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0056 0.0446
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0019 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0578 0.4769
Echinococcus granulosus neuropeptides capa receptor 0.0456 0.2456 0.4396
Brugia malayi putative neuropeptide receptor 0.0456 0.2456 0.245
Onchocerca volvulus 0.0583 0.3161 0.5902
Echinococcus multilocularis neuropeptide FF receptor 2 0.0456 0.2456 0.2764
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0453 0.0811
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0232 0.1212 0.1205
Echinococcus granulosus lamin 0.0056 0.0239 0.0428
Onchocerca volvulus 0.0035 0.0123 0.0207
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0463 0.0456
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0016 0.0019
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.0122 0.0359
Mycobacterium tuberculosis Conserved protein 0.0035 0.0123 0.0904
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0013 0.0015
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0056 0.0446
Brugia malayi CHD4 protein 0.0015 0.0009 0.0002
Loa Loa (eye worm) Smad1 0.0026 0.0073 0.0073
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0456 0.2456 0.7735
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0578 0.1072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1614 0.8884 1
Brugia malayi GnHR receptor homolog 0.0456 0.2456 0.245
Brugia malayi Bromodomain containing protein 0.0038 0.0138 0.013
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0446 0.1382
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0272 0.1589
Schistosoma mansoni hypothetical protein 0.0374 0.2001 0.6297
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Onchocerca volvulus 0.0456 0.2456 0.4581
Echinococcus granulosus biogenic amine 5HT receptor 0.0456 0.2456 0.4396
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0456 0.2456 0.7735
Echinococcus granulosus neuropeptide receptor 0.0456 0.2456 0.4396
Echinococcus multilocularis adenylate cyclase type IX 0.011 0.0535 0.0602
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0009 0.0009
Echinococcus granulosus Eukaryotic translation initiation factor 4H 0.0134 0.067 0.1199
Echinococcus granulosus somatostatin receptor 0.0456 0.2456 0.4396
Trypanosoma cruzi ISWI complex protein 0.0015 0.0011 0.0008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0211 0.0378
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0123 0.0686
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1212 0.1364
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0456 0.2456 0.245
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Echinococcus granulosus 7tm_1 domain containing protein 0.0456 0.2456 0.4396
Brugia malayi hypothetical protein 0.0256 0.1344 0.1338
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0266 0.0486
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0072
Brugia malayi Serotonin receptor 0.0456 0.2456 0.245
Echinococcus multilocularis protein dispatched 1 0.0047 0.0189 0.0213
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0035 0.0202
Echinococcus granulosus 7TM GPCR rhodopsin 0.0456 0.2456 0.4396
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0347 0.034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0035 0.0152
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0035 0.0145
Schistosoma mansoni hypothetical protein 0.0456 0.2456 0.7735
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0688 0.3745 0.3745
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0456 0.2456 0.7735
Entamoeba histolytica hypothetical protein 0.0225 0.1174 1
Schistosoma mansoni hypothetical protein 0.0456 0.2456 0.7735
Echinococcus multilocularis fmrfamide receptor 0.0456 0.2456 0.2764
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0013 0.0023
Schistosoma mansoni smad 0.0026 0.0073 0.0201
Brugia malayi neuropeptide F receptor 0.0456 0.2456 0.245
Schistosoma mansoni smad1 5 8 and 0.0026 0.0073 0.0201
Trichomonas vaginalis esterase, putative 0.0035 0.0123 0.0219
Echinococcus multilocularis g-protein coupled receptor 0.0456 0.2456 0.2764
Schistosoma mansoni neuropeptide receptor 0.0456 0.2456 0.7735
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0056 0.0279
Brugia malayi Dopamine receptor 0.0456 0.2456 0.245
Echinococcus granulosus tachykinin peptides receptor 99D 0.0456 0.2456 0.4396
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0035 0.0202
Brugia malayi hypothetical protein 0.0456 0.2456 0.245
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0035 0.0027
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0578 1
Schistosoma mansoni chromobox protein 0.0069 0.0311 0.0954
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0123 0.0361
Schistosoma mansoni alpha-1 adrenergic receptor 0.0456 0.2456 0.7735
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0122 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0162 0.0825 0.0825
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0056 0.0279
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0266 0.0486
Brugia malayi follicle stimulating hormone receptor 0.0688 0.3745 0.374
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0056 0.0279
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0456 0.2456 0.2764
Trypanosoma cruzi ISWI complex protein 0.0015 0.0011 0.0008
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0013 0.0014
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0073 0.013
Echinococcus multilocularis serotonin receptor 0.0456 0.2456 0.2764
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.023 0.0411
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0103 0.0181
Echinococcus multilocularis geminin 0.0374 0.2001 0.2253
Brugia malayi Bromodomain containing protein 0.0031 0.01 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0023 0.0045
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0266 0.0486
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0019 0.0011
Brugia malayi sulfakinin receptor protein 0.0456 0.2456 0.245
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0347 0.0347
Schistosoma mansoni zinc finger protein 0.0021 0.0043 0.0109
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0035 0.0054
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0008 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0123 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0456 0.2456 0.4396
Schistosoma mansoni hypothetical protein 0.0051 0.0211 0.0639
Echinococcus multilocularis neuropeptide Y receptor 0.0456 0.2456 0.2764
Schistosoma mansoni hypothetical protein 0.0111 0.0541 0.1682
Schistosoma mansoni opsin-like receptor 0.0456 0.2456 0.7735
Schistosoma mansoni zinc finger protein 0.0015 0.0011 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0016 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0541 0.0534
Echinococcus multilocularis rhodopsin orphan GPCR 0.0456 0.2456 0.2764
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0087 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0019 0.0011
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0165 0.0841 0.0841
Loa Loa (eye worm) hypothetical protein 0.0343 0.1828 0.1828
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0056 0.0048
Toxoplasma gondii hypothetical protein 0.0019 0.0035 0.0263
Brugia malayi Uncoordinated protein 44 0.0016 0.0013 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0456 0.2456 0.4396
Onchocerca volvulus 0.0456 0.2456 0.4581
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0171 0.1021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0272 0.0307
Schistosoma mansoni neuropeptide f receptor 76f 0.0456 0.2456 0.7735
Schistosoma mansoni neuropeptide F-like receptor 0.0456 0.2456 0.7735
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0578 0.6799
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0036
Schistosoma mansoni rab6-interacting 0.002 0.0035 0.0082
Schistosoma mansoni hypothetical protein 0.0052 0.0216 0.0654
Brugia malayi jmjC domain containing protein 0.0039 0.0141 0.0133
Schistosoma mansoni cpg binding protein 0.0028 0.0083 0.0234
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0013 0.0012
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0519 0.3113
Schistosoma mansoni hypothetical protein 0.0051 0.0211 0.0639
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1815 1 1
Brugia malayi MH2 domain containing protein 0.0026 0.0073 0.0065
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0272 0.427
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0456 0.2456 0.7735
Loa Loa (eye worm) hypothetical protein 0.0456 0.2456 0.2456
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0519 0.0961
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0123 0.0904

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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