Detailed information for compound 1172750

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 306.401 | Formula: C20H22N2O
  • H donors: 0 H acceptors: 1 LogP: 3.9 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)N1N=C(CC1c1ccc(cc1)C)c1ccc(cc1)C
  • InChi: 1S/C20H22N2O/c1-4-20(23)22-19(17-11-7-15(3)8-12-17)13-18(21-22)16-9-5-14(2)6-10-16/h5-12,19H,4,13H2,1-3H3
  • InChiKey: HQOIHSFNLBTEHE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0311 0.1347 0.1347
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0174 0.0705 0.0705
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.0861 0.1927
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0051 0.0126 0.1198
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0191 0.0307
Toxoplasma gondii phosphofructokinase PFKII 0.0062 0.0175 0.1385
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0762 0.0762
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0074 0.0234 0.1858
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Entamoeba histolytica recQ family helicase, putative 0.006 0.0168 0.1233
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.011 0.0404 0.0404
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Schistosoma mansoni alkaline phosphatase 0.0174 0.0705 0.0705
Onchocerca volvulus 0.0051 0.0125 0.028
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0059 0.0164 0.1297
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0116 0.0187
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0057 0.0154 0.1218
Trypanosoma cruzi DNA polymerase eta, putative 0.0057 0.0154 0.0332
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0074 0.0234 0.0581
Plasmodium vivax SET domain protein, putative 0.0126 0.0475 0.4523
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0062 0.0175 0.1286
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0116 0.0187
Brugia malayi PHD-finger family protein 0.0092 0.0318 0.0512
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0186 0.0762 0.0762
Echinococcus multilocularis lysine specific demethylase 6a 0.0047 0.0104 0.0104
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0182 0.0743 0.5889
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0426
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0116 0.0187
Trichomonas vaginalis DNA helicase recq, putative 0.006 0.0168 0.027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0998
Echinococcus multilocularis dna polymerase eta 0.0124 0.0466 0.0466
Loa Loa (eye worm) glutathione reductase 0.0248 0.1051 0.1691
Schistosoma mansoni zinc finger protein 0.0047 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0133 0.0509 0.0818
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0027 0.0215
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0104 0.022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0217 0.0217
Schistosoma mansoni alpha-glucosidase 0.0581 0.2619 0.2619
Toxoplasma gondii hypothetical protein 0.0155 0.0614 0.4861
Trypanosoma cruzi ISWI complex protein 0.0047 0.0106 0.0223
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0116 0.026
Echinococcus granulosus expressed protein 0.0034 0.0046 0.0046
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Echinococcus granulosus dna polymerase kappa 0.0125 0.0472 0.0472
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.059 0.0949
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0183 0.0294
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0089 0.0302 0.0486
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0135 0.052 0.1166
Echinococcus multilocularis lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0021 0.0169
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.01
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0074 0.0234 0.0338
Schistosoma mansoni cpg binding protein 0.0144 0.0564 0.0564
Brugia malayi mbt repeat family protein 0.0051 0.0125 0.0201
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0056 0.0147 0.0237
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0182 0.0743 0.23
Brugia malayi Glycosyl hydrolases family 31 protein 0.0056 0.0147 0.0237
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4337
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Loa Loa (eye worm) fli-1 protein 0.043 0.1907 0.3068
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0074 0.0074
Brugia malayi Fli-1 protein 0.043 0.1907 0.3068
Trichomonas vaginalis sucrase-isomaltase, putative 0.015 0.0589 0.0948
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0062 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Plasmodium falciparum histone acetyltransferase GCN5 0.0082 0.0271 0.2576
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.004
Echinococcus granulosus L aminoadipate semialdehyde 0.0264 0.1129 0.1129
Trichomonas vaginalis chromobox protein, putative 0.009 0.031 0.0499
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0086 0.0289 0.0765
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0111 0.0409 0.0619
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Onchocerca volvulus 0.0974 0.447 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Giardia lamblia Sgs1 DNA helicase, putative 0.0051 0.0126 0.0819
Mycobacterium ulcerans 6-phosphofructokinase 0.0228 0.0959 0.1508
Brugia malayi hypothetical protein 0.0026 0.0007 0.0011
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.0478
Giardia lamblia Kinase, PLK 0.0201 0.0833 0.6082
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0116 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0067 0.02 0.0437
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0051 0.0122 0.1163
Schistosoma mansoni survival motor neuron protein 0.0051 0.0123 0.0123
Brugia malayi Bromodomain containing protein 0.0246 0.1043 0.1677
Brugia malayi F/Y-rich N-terminus family protein 0.0085 0.0283 0.0456
Trichomonas vaginalis mercuric reductase, putative 0.0086 0.0289 0.0465
Mycobacterium tuberculosis Probable reductase 0.0565 0.2546 0.8388
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0321 0.2542
Echinococcus multilocularis microtubule associated protein 2 0.2149 1 1
Onchocerca volvulus 0.0144 0.0564 0.1261
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0062
Trypanosoma brucei phosphoglycerate kinase 0.0182 0.0743 0.1657
Brugia malayi polk-prov protein 0.0058 0.0159 0.0256
Loa Loa (eye worm) hypothetical protein 0.0058 0.0158 0.0255
Mycobacterium tuberculosis Conserved hypothetical protein 0.0506 0.2265 0.7441
Treponema pallidum phosphoglycerate kinase 0.0182 0.0743 0.5443
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0338 0.0544
Echinococcus granulosus cyclin dependent kinase 0.0099 0.0352 0.0352
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0042 0.006
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0042 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0086 0.0289 0.2748
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0039 0.0066 0.0066
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0182 0.0743 0.2449
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.1052 0.1052
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0116 0.0187
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Brugia malayi MH2 domain containing protein 0.0248 0.1053 0.1694
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0861 0.1942
Trypanosoma brucei ISWI complex protein 0.0047 0.0106 0.0205
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0125 0.0201
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0131 0.0131
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0069 0.0652
Brugia malayi Importin beta-1 subunit 0.0029 0.0021 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0116 0.0116
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0104 0.022
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0199 0.0821 0.0821
Brugia malayi Pre-SET motif family protein 0.0126 0.0475 0.0765
Onchocerca volvulus 0.0051 0.0122 0.0274
Trypanosoma brucei protein kinase, putative 0.0217 0.0906 0.2029
Onchocerca volvulus 0.0475 0.2119 0.4741
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0178 0.0722 0.0722
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0321 0.3052
Echinococcus granulosus lamin dm0 0.0029 0.0022 0.0022
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.1359 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0062 0.01
Brugia malayi cell division control protein 2 homolog 0.0099 0.0352 0.0567
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0116 0.0187
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.028 0.0626
Trypanosoma brucei glycosyl hydrolase-like protein 0.0056 0.0147 0.0299
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0089 0.0302 0.0302
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0097 0.034 0.3235
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0111 0.0409 0.3239
Giardia lamblia Kinase, CMGC GSK 0.0217 0.0906 0.6629
Brugia malayi Bromodomain containing protein 0.0125 0.0473 0.0761
Loa Loa (eye worm) RecQ helicase 0.0094 0.0327 0.0526
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0122 0.1163
Loa Loa (eye worm) hypothetical protein 0.0056 0.0147 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Echinococcus multilocularis cyclin dependent kinase 1 0.0099 0.0352 0.0352
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0099 0.0352 0.0352
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.1345 0.2163
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0086 0.0289 0.064
Schistosoma mansoni alpha-glucosidase 0.0581 0.2619 0.2619
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0339 0.148 0.238
Plasmodium vivax glutathione reductase, putative 0.0248 0.1051 1
Leishmania major DNA damage repair protein, putative 0.003 0.0025 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Loa Loa (eye worm) hypothetical protein 0.0029 0.0019 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Toxoplasma gondii aldehyde dehydrogenase 0.0186 0.0762 0.6039
Leishmania major mitochondrial DNA polymerase beta 0.096 0.4404 1
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0062 0.0593
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0158 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Brugia malayi hypothetical protein 0.0026 0.0007 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0116 0.0187
Schistosoma mansoni jumonji/arid domain-containing protein 0.0189 0.0776 0.0776
Echinococcus granulosus lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0234 0.0498
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0565 0.2546 0.8388
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0022 0.0035
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0099 0.0352 0.0767
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0565 0.2546 0.8388
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0116 0.026
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.0852 0.0852
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0064
Leishmania major phosphoglycerate kinase B, cytosolic 0.0182 0.0743 0.1657
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0099 0.0352 0.2793
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Echinococcus granulosus flap endonuclease 1 0.0028 0.0016 0.0016
Echinococcus granulosus chromobox protein 1 0.015 0.059 0.059
Plasmodium falciparum phd finger protein, putative 0.0093 0.0321 0.3052
Trichomonas vaginalis DNA helicase recq1, putative 0.0094 0.0327 0.0526
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.01
Loa Loa (eye worm) jmjC domain-containing protein 0.0189 0.0776 0.1248
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.102 0.3236
Trichomonas vaginalis rotamase, putative 0.0034 0.0042 0.0068
Echinococcus multilocularis Protein lozenge 0.006 0.0165 0.0165
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.01
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0116 0.0187
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0097 0.034 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0228 0.0959 0.3225
Schistosoma mansoni apoptosis regulator bax 0.0089 0.0302 0.0302
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0217 0.0906 0.2029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Echinococcus multilocularis chromobox protein 1 0.015 0.059 0.059
Brugia malayi beta-lactamase 0.0038 0.0062 0.01
Loa Loa (eye worm) CXXC zinc finger family protein 0.0144 0.0564 0.0907
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0182 0.0743 0.1195
Onchocerca volvulus 0.015 0.0591 0.1322
Trypanosoma brucei DNA polymerase IV, putative 0.0125 0.0472 0.1039
Loa Loa (eye worm) hypothetical protein 0.0182 0.0743 0.1195
Loa Loa (eye worm) apoptosis regulator protein 0.0089 0.0302 0.0486
Loa Loa (eye worm) beta-lactamase 0.0038 0.0062 0.01
Echinococcus multilocularis phd:f box containing protein 0.0047 0.0104 0.0104
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0116 0.0116
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0182 0.0743 0.5889
Leishmania major alpha glucosidase II subunit, putative 0.015 0.0589 0.1307
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0056 0.0147 0.1082
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0191 0.0307
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.0833 0.1877
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0165 0.0265
Brugia malayi Glycosyl hydrolases family 31 protein 0.0675 0.3061 0.4924
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0565 0.2546 0.8388
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Echinococcus multilocularis roundabout 2 0.0033 0.004 0.004
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0027 0.0026
Echinococcus granulosus jumonji domain containing 1A 0.0047 0.0104 0.0104
Brugia malayi Pre-SET motif family protein 0.0856 0.3915 0.6298
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0116 0.0116
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0086 0.0289 0.0622
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0016 0.0117
Echinococcus granulosus GA binding protein alpha chain 0.0142 0.0551 0.0551
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0025 0.0003 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0217 0.0906 0.1458
Brugia malayi TAR-binding protein 0.0065 0.0191 0.0307
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0064
Brugia malayi CHD4 protein 0.0039 0.0066 0.0107
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0158 0.0255
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0077 0.0249 0.0249
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0116 0.0116
Echinococcus granulosus neuroglian 0.0026 0.0008 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Onchocerca volvulus 0.0066 0.0195 0.0435
Schistosoma mansoni bromodomain containing protein 0.0029 0.002 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0332 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0125
Loa Loa (eye worm) phosphofructokinase 0.0228 0.0959 0.1543
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0039 0.0066 0.0066
Giardia lamblia Phosphoglycerate kinase 0.0182 0.0743 0.5415
Echinococcus granulosus cpg binding protein 0.0158 0.063 0.063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0332 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.028 0.045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Echinococcus multilocularis protoporphyrinogen oxidase 0.0051 0.0122 0.0122
Schistosoma mansoni microtubule-associated protein tau 0.2149 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0123 0.0197
Brugia malayi nuclear receptor RXR 0.0026 0.0007 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0321 0.2542
Echinococcus multilocularis Chromobox protein 3 0.0025 0.000000024027 0.000000024027
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0074 0.0074
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4671
Echinococcus multilocularis zinc finger protein 0.0076 0.0241 0.0241
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0103 0.0371 0.081
Echinococcus multilocularis cpg binding protein 0.0158 0.063 0.063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0116 0.0187
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.0021
Echinococcus granulosus lamin 0.0029 0.0022 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0116 0.0116
Treponema pallidum licC protein (licC) 0.0111 0.0409 0.2968
Trypanosoma cruzi DNA polymerase eta, putative 0.0124 0.0466 0.1044
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0125
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0074 0.0234 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0051 0.0122 0.1163
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.0852 0.0852
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.3261 0.5225
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.006 0.0167 0.159
Chlamydia trachomatis phosphoglycerate kinase 0.0182 0.0743 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0332 0.0534
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0051 0.0122 0.0216
Echinococcus multilocularis L aminoadipate semialdehyde 0.0264 0.1129 0.1129
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0051 0.0122 0.0122
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0042 0.0336
Echinococcus granulosus dna polymerase eta 0.0124 0.0466 0.0466
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0165 0.0659 0.1482
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Schistosoma mansoni hypothetical protein 0.0091 0.0311 0.0311
Echinococcus granulosus lysine specific demethylase 5A 0.0189 0.0776 0.0776
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0086 0.0289 0.2682
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1709 0.7929 0.7929
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0589 0.1323
Mycobacterium ulcerans hypothetical protein 0.0038 0.0062 0.006
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0218 0.046
Plasmodium falciparum thioredoxin reductase 0.0086 0.0289 0.2748
Brugia malayi Glycosyl hydrolases family 31 protein 0.015 0.0589 0.0948
Entamoeba histolytica cell division protein kinase 2, putative 0.0099 0.0352 0.2594
Entamoeba histolytica cell division protein kinase 2, putative 0.0099 0.0352 0.2594
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0062 0.006
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.01
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0016 0.0026
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0015 0.0015
Echinococcus multilocularis alkaline phosphatase 0.0174 0.0705 0.0705
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0178 0.0722 0.0722
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0182 0.0743 0.1673
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0607 0.2743 0.9055
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0159 0.0327
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0203
Schistosoma mansoni glutaminase 0.1345 0.6217 0.6217
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0116 0.0116
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0182 0.0743 0.2028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.1359 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.0605 0.0936
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0016 0.0019
Onchocerca volvulus Serine\/threonine kinase homolog 0.0201 0.0833 0.1863
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0059 0.0162 0.1288
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0003 0.0021
Echinococcus granulosus JmjC domain containing protein 4 0.0047 0.0104 0.0104
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0321 0.0321
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0042 0.0312
Entamoeba histolytica acetyltransferase, GNAT family 0.0082 0.0271 0.1992
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0099 0.0352 0.0567
Echinococcus granulosus geminin 0.0364 0.16 0.16
Trypanosoma cruzi cdc2-related kinase 1 0.0099 0.0352 0.0784
Giardia lamblia Kinase, CMGC GSK 0.0217 0.0906 0.6629
Plasmodium vivax importin-beta 2, putative 0.0029 0.0021 0.0203
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.003 0.0027 0.0027
Leishmania major UDP-galactopyranose mutase 0.0051 0.0122 0.0242
Trypanosoma brucei glucosidase, putative 0.015 0.0589 0.1307
Trypanosoma cruzi cdc2-related kinase 1 0.0099 0.0352 0.0784
Onchocerca volvulus 0.0029 0.0022 0.0048
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0959 0.2149
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0338 0.0931
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0125 0.028
Brugia malayi CXXC zinc finger family protein 0.0144 0.0564 0.0907
Leishmania major trypanothione reductase 0.0248 0.1051 0.2359
Echinococcus granulosus neutral alpha glucosidase AB 0.015 0.0589 0.0589
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0125 0.0125
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0099 0.0352 0.0567
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0062 0.0106
Giardia lamblia DINP protein human, muc B family 0.0103 0.0371 0.2645
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0264 0.1129 0.1129
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0025 0.024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0332 0.0332
Leishmania major hypothetical protein, conserved 0.0038 0.0062 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0218 0.035
Schistosoma mansoni kinase 0.0104 0.0374 0.0374
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0086 0.0289 0.0465
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.031 0.0694
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0047 0.0104 0.0828
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0086 0.0289 0.0622
Schistosoma mansoni flap endonuclease-1 0.0025 0.0003 0.0003
Echinococcus multilocularis bloom syndrome protein 0.0094 0.0327 0.0327
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.0122 0.0203
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Echinococcus multilocularis lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Schistosoma mansoni alkaline phosphatase 0.0174 0.0705 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0116 0.0187
Leishmania major glycosyl hydrolase-like protein 0.0056 0.0147 0.0299
Toxoplasma gondii histone lysine-specific demethylase 0.0051 0.0122 0.0969
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Brugia malayi Flap endonuclease-1 0.0028 0.0016 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0051 0.0122 0.1163
Brugia malayi phosphofructokinase 0.0228 0.0959 0.1543
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0116 0.0187
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0628 0.2843 0.9391
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Brugia malayi intracellular kinase 0.0217 0.0906 0.1458
Trypanosoma brucei DNA polymerase IV, putative 0.0125 0.0472 0.1039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Giardia lamblia PHD finger protein 15 0.0093 0.0321 0.227
Brugia malayi jmjC domain containing protein 0.0189 0.0776 0.1248
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0116 0.0187
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0201 0.0833 0.0833
Entamoeba histolytica recQ family DNA helicase 0.0026 0.0008 0.0056
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0089 0.0302 0.0302
Trichomonas vaginalis set domain proteins, putative 0.0974 0.447 0.719
Trypanosoma brucei unspecified product 0.0066 0.0197 0.0413
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.0622
Trypanosoma brucei DNA polymerase eta, putative 0.0124 0.0466 0.1027
Schistosoma mansoni chromobox protein 0.015 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0047 0.0104 0.0168
Echinococcus granulosus intestinal type alkaline phosphatase 0.0174 0.0705 0.0705
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0959 0.1543
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0047 0.0104 0.0202
Loa Loa (eye worm) hypothetical protein 0.0089 0.0302 0.0486
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.096 0.4404 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.002 0.0033
Mycobacterium ulcerans hypothetical protein 0.0111 0.0409 0.0619
Trypanosoma brucei unspecified product 0.0118 0.0439 0.0964
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0062 0.0175 0.1385
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0475 0.3767
Schistosoma mansoni intermediate filament proteins 0.0029 0.0022 0.0022
Trichomonas vaginalis chromobox protein, putative 0.015 0.059 0.0949
Trypanosoma cruzi cdc2-related kinase 3 0.0099 0.0352 0.0784
Loa Loa (eye worm) hypothetical protein 0.0264 0.1129 0.1816
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.0605 0.1832
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0046 0.0074
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.0122 0.0203
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.015
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0312 0.1351 0.1351
Brugia malayi Bloom's syndrome protein homolog 0.0094 0.0327 0.0526
Schistosoma mansoni cell adhesion molecule 0.0028 0.0015 0.0015
Leishmania major DNA polymerase kappa, putative 0.003 0.0025 0.0021
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.015 0.0589 0.0948
Echinococcus granulosus histone acetyltransferase KAT2B 0.0296 0.1277 0.1277
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0086 0.0289 0.2748
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.1359 1
Mycobacterium ulcerans dehydrogenase 0.0051 0.0122 0.0157
Leishmania major DNA polymerase kappa, putative 0.0103 0.0371 0.081
Leishmania major phosphoglycerate kinase C, glycosomal 0.0182 0.0743 0.1657
Trichomonas vaginalis chromobox protein, putative 0.009 0.031 0.0499
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0086 0.0289 0.0622
Trypanosoma brucei DNA polymerase IV, putative 0.0118 0.0439 0.0964
Brugia malayi intermediate filament protein 0.0029 0.0022 0.0035
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0116 0.0116
Echinococcus granulosus histone lysine methyltransferase setb 0.0178 0.0722 0.0722
Mycobacterium ulcerans phosphoglycerate kinase 0.0182 0.0743 0.1159
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0321 0.0321
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0099 0.0352 0.0767
Loa Loa (eye worm) hypothetical protein 0.0147 0.0575 0.0925
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0217 0.0906 0.1458
Schistosoma mansoni lozenge 0.006 0.0165 0.0165
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0086 0.0289 0.2748
Echinococcus multilocularis cyclin dependent kinase 1 0.0099 0.0352 0.0352
Loa Loa (eye worm) CHromoDomain protein family member 0.0039 0.0066 0.0107
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0175 0.1663
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.0338 0.0544
Trypanosoma brucei trypanothione reductase 0.0248 0.1051 0.2359
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0116 0.0187
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0021 0.0012
Mycobacterium ulcerans DNA polymerase IV 0.0125 0.0472 0.0722
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Trichomonas vaginalis helicase, putative 0.0033 0.0038 0.0062
Brugia malayi glutathione reductase 0.0248 0.1051 0.1691
Schistosoma mansoni hypothetical protein 0.0315 0.1367 0.1367
Plasmodium falciparum flap endonuclease 1 0.0028 0.0016 0.0151
Onchocerca volvulus 0.0038 0.0062 0.0139
Schistosoma mansoni blooms syndrome DNA helicase 0.0068 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0095 0.0332 0.0534
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0174 0.0705 0.0705
Brugia malayi Thioredoxin reductase 0.0248 0.1051 0.1691
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Echinococcus multilocularis phosphoglycerate kinase 1 0.0182 0.0743 0.0743
Echinococcus granulosus twitchin 0.003 0.0025 0.0025
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0367 0.161 0.161
Brugia malayi SWIRM domain containing protein 0.0051 0.0122 0.0197
Giardia lamblia DNA damage repair protein 0.003 0.0025 0.0069
Echinococcus granulosus tar DNA binding protein 0.0065 0.0191 0.0191
Brugia malayi serine/threonine-protein kinase plk-2 0.0201 0.0833 0.134
Loa Loa (eye worm) hypothetical protein 0.0248 0.1052 0.1693
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.0171 0.0171
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0217 0.0906 0.2044
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0332 0.0332
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Trypanosoma cruzi trypanothione reductase, putative 0.0248 0.1051 0.2373
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0116 0.0116
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0047 0.0104 0.0828
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0154 0.0248
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Loa Loa (eye worm) hypothetical protein 0.0051 0.0126 0.0203
Echinococcus multilocularis thioredoxin glutathione reductase 0.025 0.1061 0.1061
Brugia malayi Ets-domain containing protein 0.0142 0.0551 0.0886
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0116 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0116 0.0187
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0191 0.0307
Echinococcus multilocularis lysine specific demethylase 5A 0.0175 0.0709 0.0709
Toxoplasma gondii thioredoxin reductase 0.0248 0.1051 0.8329
Mycobacterium tuberculosis Probable dehydrogenase 0.0565 0.2546 0.8388
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0025 0.0025
Schistosoma mansoni cpg binding protein 0.0158 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Loa Loa (eye worm) thioredoxin reductase 0.0248 0.1051 0.1691
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0116 0.0187
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0085 0.0286 0.2717
Brugia malayi hypothetical protein 0.0032 0.0034 0.0055
Echinococcus multilocularis dna polymerase kappa 0.0125 0.0472 0.0472
Brugia malayi nuclear hormone receptor 0.0049 0.0116 0.0187
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.0338 0.0338
Schistosoma mansoni phosphatidylserine receptor 0.0047 0.0104 0.0104
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0116 0.0116
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0321 0.0516
Trichomonas vaginalis esterase, putative 0.0038 0.0062 0.01
Plasmodium falciparum glutathione reductase 0.0086 0.0289 0.2748
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0047 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Trypanosoma brucei polo-like protein kinase 0.0201 0.0833 0.1862
Loa Loa (eye worm) hypothetical protein 0.0095 0.0332 0.0534
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0007 0.0007
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0628 0.2843 0.9391
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0016 0.0151
Plasmodium falciparum phosphoglycerate kinase 0.0182 0.0743 0.707
Schistosoma mansoni hypothetical protein 0.0051 0.0123 0.0123
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0008 0.0008
Trypanosoma brucei phosphoglycerate kinase, putative 0.0067 0.02 0.0419
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0051 0.0126 0.0126
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0063 0.0181 0.0292
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.0021
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0131 0.0131
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0475 0.0475
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0062 0.01
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Giardia lamblia Histone acetyltransferase GCN5 0.0082 0.0271 0.1897
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0077 0.0249 0.0249
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0959 0.1543
Trypanosoma brucei mitochondrial DNA polymerase beta 0.096 0.4404 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.0338 0.0338
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0264 0.1129 0.1816
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.011 0.0404 0.0404
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0116 0.0187
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0086 0.0289 0.2748
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0099 0.0352 0.0567
Plasmodium vivax JmjC domain containing protein 0.0047 0.0104 0.0994
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0565 0.2546 0.8932
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Brugia malayi glutaminase DH11.1 0.1345 0.6217 1
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0125 0.0125
Plasmodium falciparum glutathione reductase 0.0248 0.1051 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0116 0.0187
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0364 0.16 0.16
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.015 0.0589 0.0948
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Echinococcus multilocularis chromobox protein 1 0.015 0.059 0.059
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0175 0.1663
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.3261 0.5225
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Entamoeba histolytica phosphoglycerate kinase, putative 0.0182 0.0743 0.5468
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0174 0.0705 0.0705
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Mycobacterium ulcerans lipase LipD 0.0038 0.0062 0.006
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0234 0.2231
Trypanosoma brucei phosphoglycerate kinase 0.0067 0.02 0.0419
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0218 0.0218
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0165 0.0165
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0051 0.0126 0.0203
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0182 0.0743 0.1195
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0116 0.0116
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Trichomonas vaginalis maltase-glucoamylase, putative 0.015 0.0589 0.0948
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0256
Echinococcus granulosus protein kinase shaggy 0.0217 0.0906 0.0906
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Brugia malayi nuclear receptor NHR-88 0.0049 0.0116 0.0187
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0856 0.3915 0.6298
Schistosoma mansoni DNA helicase recq1 0.0051 0.0126 0.0126
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0419
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0116 0.0187
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0086 0.0289 0.0217
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0074 0.0234 0.1679
Mycobacterium ulcerans hypothetical protein 0.0111 0.0409 0.0619
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.1053 0.1694
Mycobacterium ulcerans monoamine oxidase 0.0051 0.0122 0.0157
Plasmodium falciparum thioredoxin reductase 0.0248 0.1051 1
Mycobacterium ulcerans beta-lactamase 0.0038 0.0062 0.006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0186 0.0762 0.1701
Echinococcus granulosus importin subunit beta 1 0.0029 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0159 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Schistosoma mansoni nephrin 0.0026 0.0008 0.0008
Plasmodium falciparum glycogen synthase kinase 3 0.0217 0.0906 0.8622
Echinococcus multilocularis geminin 0.0364 0.16 0.16
Echinococcus granulosus thioredoxin glutathione reductase 0.025 0.1061 0.1061
Brugia malayi Heterochromatin protein 1 0.015 0.059 0.0949
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0218 0.0218
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0083 0.0133
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0203
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.0605 0.1951
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0116 0.0187
Plasmodium falciparum protoporphyrinogen oxidase 0.0051 0.0122 0.1163
Schistosoma mansoni hypothetical protein 0.031 0.1345 0.1345
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0116 0.0187
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0097 0.034 0.2695
Echinococcus granulosus chromobox protein 1 0.015 0.059 0.059
Echinococcus granulosus bloom syndrome protein 0.0094 0.0327 0.0327
Brugia malayi hypothetical protein 0.0051 0.0122 0.0197
Plasmodium vivax thioredoxin reductase, putative 0.0248 0.1051 1
Brugia malayi Phosphoglycerate kinase 0.0067 0.02 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0352 0.0352
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0116 0.0116
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0089 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0084 0.028 0.045
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0135 0.052 0.1166
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0022 0.0035
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0191 0.0191
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Entamoeba histolytica protein kinase, putative 0.0217 0.0906 0.6668
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Echinococcus granulosus alkaline phosphatase 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0093 0.0321 0.0516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0104 0.0168
Trichomonas vaginalis chromobox protein, putative 0.015 0.059 0.0949
Plasmodium falciparum protein kinase 5 0.0099 0.0352 0.3353
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Brugia malayi RNA, U transporter 1 0.0083 0.0274 0.044
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0116 0.0187
Plasmodium vivax phosphoglycerate kinase, putative 0.0182 0.0743 0.707
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.015 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0103 0.0371 0.1043
Schistosoma mansoni DNA polymerase eta 0.0124 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0409 0.117
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0174 0.0705 0.0705
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Schistosoma mansoni DNA helicase recq5 0.0051 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0178 0.0722 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0352 0.0352
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0861 0.1942
Echinococcus multilocularis 6 phosphofructokinase 0.0228 0.0959 0.0959
Echinococcus multilocularis GA binding protein alpha chain 0.0142 0.0551 0.0551
Echinococcus multilocularis cyclin dependent kinase 0.0099 0.0352 0.0352
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0346
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Echinococcus multilocularis dnaJ subfamily B 0.2055 0.9559 0.9559
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0165 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0016 0.0026
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0116 0.0187
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0104 0.0104
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0086 0.0289 0.2288
Brugia malayi Phosphoglycerate kinase 0.0182 0.0743 0.1195
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0027 0.0026
Toxoplasma gondii 6-phosphofructokinase 0.0062 0.0175 0.1385
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0135 0.052 0.1166
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0409 0.117
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0027 0.0215
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.0021
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0116 0.0187
Toxoplasma gondii NADPH-glutathione reductase 0.0086 0.0289 0.2288
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0959 0.0959
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0199 0.0821 0.0821
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0475 0.0475
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0042 0.006
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0367 0.161 0.161
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0125 0.0125
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0364
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0122 0.0261
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0056 0.0147 0.0329
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.0785 0.1263
Schistosoma mansoni protein phosphatase 2C 0.0047 0.0104 0.0104
Trypanosoma brucei cdc2-related kinase 1 0.0099 0.0352 0.0767
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0135 0.052 0.1149
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0116 0.0116
Onchocerca volvulus 0.0264 0.1129 0.2525
Schistosoma mansoni eyes absent homolog 0.0095 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0024
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0025 0.024
Trypanosoma cruzi ISWI complex protein 0.0047 0.0106 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0051 0.0126 0.0126
Echinococcus granulosus histone acetyltransferase KAT2B 0.0097 0.034 0.034
Plasmodium falciparum JmjC domain-containing protein, putative 0.0047 0.0104 0.0994
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0361 0.0581
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0217 0.0906 0.0906
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Echinococcus granulosus jumonji domain containing protein 0.0129 0.0492 0.0492
Echinococcus granulosus roundabout 2 0.0033 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0034 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0071 0.0115
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0125 0.0125
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0008 0.006
Entamoeba histolytica hypothetical protein 0.0074 0.0234 0.1725
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0077 0.0077
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0454 0.2024 0.4575
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0217 0.0906 0.7181
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0217 0.0906 0.0906
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0077 0.0077
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0218 0.0218
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0959 0.2164
Loa Loa (eye worm) hypothetical protein 0.0124 0.0466 0.075
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0074 0.0074
Trichomonas vaginalis glutathione reductase, putative 0.0086 0.0289 0.0465
Schistosoma mansoni phosphoglycerate kinase 0.0182 0.0743 0.0743
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.015 0.0589 0.0948
Schistosoma mansoni alpha glucosidase 0.015 0.0589 0.0589
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0074 0.0234 0.1807
Echinococcus multilocularis cyclin dependent kinase 5 0.0099 0.0352 0.0352
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0312 0.1351 0.1351
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0083 0.0133
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0116 0.0116
Schistosoma mansoni amine oxidase 0.0051 0.0122 0.0122
Echinococcus granulosus peregrin 0.0107 0.039 0.039
Leishmania major hypothetical protein, conserved 0.0047 0.0106 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0116 0.0187
Schistosoma mansoni gabp alpha 0.0142 0.0551 0.0551
Mycobacterium ulcerans hypothetical protein 0.0506 0.2265 0.3618
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Schistosoma mansoni hypothetical protein 0.2055 0.9559 0.9559
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0097 0.034 0.0547
Brugia malayi Immunoglobulin I-set domain containing protein 0.0339 0.148 0.238
Trypanosoma brucei phosphoglycerate kinase 0.0182 0.0743 0.1657
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0116 0.026
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0675 0.3061 0.4924
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0116 0.0186
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0116 0.0116
Loa Loa (eye worm) bromodomain containing protein 0.0062 0.0175 0.0282
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0116 0.0187
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0039 0.0066 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Onchocerca volvulus 0.0051 0.0123 0.0275
Brugia malayi 6-phosphofructokinase 0.0228 0.0959 0.1543
Echinococcus granulosus phosphoglycerate kinase 1 0.0182 0.0743 0.0743
Trichomonas vaginalis DNA helicase recq, putative 0.0094 0.0327 0.0526
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Schistosoma mansoni hypothetical protein 0.0047 0.0106 0.0106
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0086 0.0289 0.0426
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0125 0.0125
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0062 0.0175 0.1183
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0589 0.1323
Loa Loa (eye worm) hypothetical protein 0.0475 0.2119 0.3409
Loa Loa (eye worm) hypothetical protein 0.0051 0.0125 0.0201
Trypanosoma brucei cdc2-related kinase 3 0.0099 0.0352 0.0767
Trichomonas vaginalis rotamase, putative 0.0034 0.0046 0.0074
Brugia malayi RNA binding protein 0.0065 0.0191 0.0307
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.0906 0.6668
Brugia malayi hypothetical protein 0.0248 0.1052 0.1693
Leishmania major hypothetical protein, conserved 0.0208 0.0861 0.1927
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.028 0.1204 0.1937
Brugia malayi PHD-finger family protein 0.0093 0.0321 0.0516
Onchocerca volvulus Tyrosine kinase homolog 0.0317 0.1374 0.3075
Echinococcus multilocularis neutral alpha glucosidase AB 0.015 0.0589 0.0589
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0062 0.0175 0.1237
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0056 0.0147 0.0317
Giardia lamblia Kinase, CMGC CDK 0.0099 0.0352 0.2506
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0131 0.0131
Brugia malayi Ets-domain containing protein 0.0142 0.0551 0.0886
Loa Loa (eye worm) runx1 0.006 0.0165 0.0265
Leishmania major DNA polymerase eta, putative 0.0057 0.0154 0.0314
Echinococcus multilocularis lamin 0.0029 0.0022 0.0022
Echinococcus granulosus fetal alzheimer antigen falz 0.0077 0.0249 0.0249
Schistosoma mansoni bromodomain containing protein 0.021 0.0873 0.0873
Schistosoma mansoni hypothetical protein 0.0032 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Leishmania major ATP-dependent phosphofructokinase 0.0228 0.0959 0.2149
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0182 0.0743 0.1673
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Toxoplasma gondii ABC1 family protein 0.0038 0.0062 0.0494
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0178 0.0722 0.0722
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0051 0.0122 0.0157
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0007 0.0007
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0116 0.0116
Schistosoma mansoni jumonji/arid domain-containing protein 0.0189 0.0776 0.0776
Brugia malayi Bromodomain containing protein 0.0107 0.039 0.0628
Loa Loa (eye worm) hypothetical protein 0.0066 0.0195 0.0313
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.0171 0.0171
Echinococcus multilocularis JmjC domain containing protein 4 0.0047 0.0104 0.0104
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0074 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0833 0.0833
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0186 0.0762 0.2364
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.046
Schistosoma mansoni cpg binding protein 0.0158 0.063 0.063
Schistosoma mansoni lamin 0.0029 0.0022 0.0022
Leishmania major hypothetical protein, conserved 0.0047 0.0104 0.0202
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4337
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0086 0.0289 0.0622
Echinococcus multilocularis peregrin 0.0107 0.039 0.039
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0116 0.0116
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0016 0.0126
Loa Loa (eye worm) RNA binding protein 0.0065 0.0191 0.0307
Schistosoma mansoni hypothetical protein 0.0093 0.0321 0.0321
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0116 0.0116
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0042 0.0079
Onchocerca volvulus 0.0049 0.0116 0.026
Echinococcus granulosus phd:f box containing protein 0.0047 0.0104 0.0104
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0628 0.2843 1
Giardia lamblia Kinase, CMGC CDK 0.0099 0.0352 0.2506
Trichomonas vaginalis glutaminase, putative 0.1345 0.6217 1
Brugia malayi ImpB/MucB/SamB family protein 0.0124 0.0466 0.075
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0201 0.0833 0.134
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0086 0.0289 0.064
Echinococcus multilocularis neuroglian 0.0026 0.0008 0.0008
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0016 0.0016
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0234 0.2231
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0454 0.2024 0.4575
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0607 0.2743 0.439
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0062 0.0062
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0125 0.0472 0.0759
Loa Loa (eye worm) glutaminase 0.1345 0.6217 1
Leishmania major DNA polymerase eta, putative 0.0124 0.0466 0.1027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0086 0.0289 0.0217
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.0906 0.6668
Onchocerca volvulus 0.0029 0.0022 0.0048
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0125 0.0125
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0062 0.0175 0.0281
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0056 0.0147 0.0237
Echinococcus multilocularis 0.0051 0.0122 0.0122
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.0338 0.0338
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0125 0.0125
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0175 0.0846
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0248 0.1051 0.334
Mycobacterium ulcerans glutaminase 0.1345 0.6217 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0069 0.0652
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0186 0.0762 0.0762
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0158 0.0158
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0332 0.0534
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0025 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0217 0.0907 0.1459
Trypanosoma brucei unspecified product 0.0066 0.0197 0.0413
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0346
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0607 0.2743 1
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.004
Schistosoma mansoni ets-related 0.043 0.1907 0.1907
Schistosoma mansoni hypothetical protein 0.0063 0.0183 0.0183
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0959 0.0959
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0998
Echinococcus granulosus intermediate filament protein 0.0029 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0089 0.0302 0.0302
Onchocerca volvulus 0.0309 0.134 0.2999
Mycobacterium ulcerans oxidoreductase 0.0051 0.0122 0.0157
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0142 0.0551 0.0886
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0051 0.0122 0.1163
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0175 0.0846
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0116 0.0116
Leishmania major phosphopantetheinyl transferase-like protein 0.0074 0.0234 0.0498
Plasmodium falciparum importin beta, putative 0.0029 0.0021 0.0203
Echinococcus multilocularis expressed protein 0.0034 0.0046 0.0046
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0116 0.0116
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0122 0.0261
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Echinococcus granulosus lysine specific demethylase 6a 0.0047 0.0104 0.0104
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0201 0.0833 0.1862
Loa Loa (eye worm) glutaminase 2 0.1345 0.6217 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.0217 0.0906 0.8622
Brugia malayi amine oxidase, flavin-containing family protein 0.0051 0.0122 0.0197
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0622
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0762 0.0762
Giardia lamblia NADH oxidase lateral transfer candidate 0.0086 0.0289 0.2032
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.1053 0.1694
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0454 0.2024 0.4585
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0667 0.3023 1
Brugia malayi PHD-finger family protein 0.0044 0.0093 0.015
Brugia malayi hypothetical protein 0.0095 0.0332 0.0534
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0097 0.034 0.2695
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0218 0.035
Loa Loa (eye worm) acetyltransferase 0.0312 0.1351 0.2174
Schistosoma mansoni phd/f-box containing protein 0.0047 0.0104 0.0104
Echinococcus multilocularis jumonji domain containing 1A 0.0047 0.0104 0.0104
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0607 0.2743 0.9642
Mycobacterium ulcerans DNA polymerase IV 0.0125 0.0472 0.0722
Brugia malayi AF-10 protein 0.003 0.0027 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0046 0.0074
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.028 0.045
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0051 0.0122 0.0122
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0116 0.0116
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0218 0.1601
Echinococcus multilocularis musashi 0.0029 0.0022 0.0022
Onchocerca volvulus Alhambra homolog 0.0093 0.0321 0.0718
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0022 0.0035
Brugia malayi steroid hormone receptor 0.0049 0.0116 0.0187
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0007 0.0007
Onchocerca volvulus 0.0038 0.0062 0.0139
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Brugia malayi hypothetical protein 0.0475 0.2119 0.3409
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Echinococcus granulosus cyclin dependent kinase 1 0.0099 0.0352 0.0352
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Echinococcus multilocularis lamin dm0 0.0029 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0371 0.081
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0025 0.0021
Brugia malayi Protein kinase domain containing protein 0.0099 0.0352 0.0567
Echinococcus granulosus zinc finger protein 0.0076 0.0241 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0116 0.0116
Onchocerca volvulus 0.0217 0.0906 0.2027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.0622
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0037 0.0059 0.0464
Echinococcus granulosus snurportin 1 0.031 0.1345 0.1345
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0158 0.0158
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0228 0.0959 0.3029
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0565 0.2546 0.8388
Plasmodium vivax protein kinase Crk2 0.0099 0.0352 0.3353
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Trichomonas vaginalis CMGC family protein kinase 0.0217 0.0906 0.1458
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0116 0.0116
Treponema pallidum NADH oxidase 0.0086 0.0289 0.2081
Onchocerca volvulus 0.039 0.1722 0.3852
Trichomonas vaginalis maltase-glucoamylase, putative 0.0056 0.0147 0.0237
Echinococcus multilocularis protein kinase shaggy 0.0217 0.0906 0.0906
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0201 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.0121 0.0454 0.073
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0089 0.0302 0.0302
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0228 0.0959 0.704
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.096 0.4404 1
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Schistosoma mansoni jumonji domain containing protein 0.0304 0.1316 0.1316
Schistosoma mansoni amine oxidase 0.0051 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Echinococcus granulosus Chromobox protein 3 0.0025 0.000000024027 0.000000024027
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0051 0.0126 0.0126
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0131 0.0131
Schistosoma mansoni chromobox protein 0.015 0.059 0.059
Schistosoma mansoni zinc finger protein 0.0076 0.0241 0.0241
Schistosoma mansoni rotamase 0.0034 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0475 0.2119 0.3409
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0063 0.0181 0.0292
Entamoeba histolytica serine/threonine protein kinase, putative 0.0201 0.0833 0.6128
Brugia malayi jmjC domain containing protein 0.0367 0.161 0.259
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0021 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0289 0.064
Schistosoma mansoni lamin 0.0029 0.0022 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.0338 0.2486
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0165 0.0265
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0176 0.0712 0.1145
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0439 0.0439
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0234 0.0619
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.1052 0.1052
Trichomonas vaginalis DNA polymerase eta, putative 0.0125 0.0472 0.0759
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0046 0.0074
Brugia malayi 6-phosphofructokinase 0.0228 0.0959 0.1543
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0056 0.0147 0.0317
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0217 0.0906 0.0906
Echinococcus granulosus dnaJ subfamily B 0.2055 0.9559 0.9559
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0321 0.0321
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0154 0.0248
Brugia malayi mbt repeat family protein 0.0051 0.0125 0.0201
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.0833 0.1877
Schistosoma mansoni phosphoglycerate kinase 0.0182 0.0743 0.0743
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0158 0.0158
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0116 0.0116
Schistosoma mansoni coup transcription factor 0.0049 0.0116 0.0116
Echinococcus granulosus cyclin dependent kinase 5 0.0099 0.0352 0.0352
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.0478
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.0338 0.0338
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0021 0.0012
Echinococcus granulosus 6 phosphofructokinase 0.0228 0.0959 0.0959
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0361 0.0581
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0175 0.1663
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0217 0.0906 0.1458
Onchocerca volvulus 0.0038 0.0062 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Brugia malayi chromobox protein homolog 3 0.0084 0.028 0.045
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.1359 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0051 0.0126 0.0126
Schistosoma mansoni importin beta-1 0.0029 0.0021 0.0021
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0074 0.0234 0.1858
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0096 0.0335 0.0539
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0086 0.0289 0.0426
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0034
Echinococcus multilocularis snurportin 1 0.031 0.1345 0.1345
Brugia malayi SET domain containing protein 0.0032 0.0036 0.0058
Trypanosoma cruzi cdc2-related kinase 3 0.0099 0.0352 0.0784
Toxoplasma gondii histone lysine methyltransferase SET1 0.0293 0.1262 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0628 0.2843 0.9391
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0122 0.1163
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Schistosoma mansoni hypothetical protein 0.0364 0.16 0.16
Schistosoma mansoni lipoxygenase 0.006 0.0165 0.0165
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0034 0.0034
Brugia malayi ecdysteroid receptor 0.0049 0.0116 0.0187
Loa Loa (eye worm) hypothetical protein 0.0118 0.0439 0.0706
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0175 0.1663
Brugia malayi acetyltransferase, GNAT family protein 0.0312 0.1351 0.2174
Loa Loa (eye worm) MBCTL1 0.0058 0.0158 0.0255
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.0035
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0116 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4 Inhibition of bovine mitochondrial MAOA ChEMBL. 18281126
IC50 (binding) = 4 Inhibition of bovine mitochondrial MAOB ChEMBL. 18281126

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.