Detailed information for compound 1228149

Basic information

Technical information
  • TDR Targets ID: 1228149
  • Name: 2-methylpropyl 3-methyl-4-oxo-6-thiophen-2-yl -1,5,6,7-tetrahydroindole-2-carboxylate
  • MW: 331.429 | Formula: C18H21NO3S
  • H donors: 1 H acceptors: 2 LogP: 3.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(COC(=O)c1[nH]c2c(c1C)C(=O)CC(C2)c1cccs1)C
  • InChi: 1S/C18H21NO3S/c1-10(2)9-22-18(21)17-11(3)16-13(19-17)7-12(8-14(16)20)15-5-4-6-23-15/h4-6,10,12,19H,7-9H2,1-3H3
  • InChiKey: WOPUGMNDPRRTGL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • isobutyl 3-methyl-4-oxo-6-(2-thienyl)-1,5,6,7-tetrahydroindole-2-carboxylate
  • 3-methyl-4-oxo-6-(2-thienyl)-1,5,6,7-tetrahydroindole-2-carboxylic acid isobutyl ester
  • 4-keto-3-methyl-6-(2-thienyl)-1,5,6,7-tetrahydroindole-2-carboxylic acid isobutyl ester
  • EU-0024807
  • MLS000520138
  • IVK/2008111
  • SMR000130551

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni z-protein (S1r protein) 0.0025 0.0017 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0067 0.0147 0.0295
Entamoeba histolytica tubulin gamma chain 0.0943 0.2833 0.5672
Loa Loa (eye worm) tubulin alpha chain 0.1263 0.3816 0.7649
Plasmodium falciparum glutathione reductase 0.0033 0.0043 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Schistosoma mansoni amine GPCR 0.0021 0.0005 0.0008
Brugia malayi conserved hypotetical protein 0.0029 0.0031 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0256 0.05
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0025 0.0017 0.0017
Trichomonas vaginalis tubulin, putative 0.0503 0.1486 0.2977
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0236 0.0373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0067 0.0147 0.0295
Leishmania major beta tubulin 0.1646 0.4988 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0033
Echinococcus multilocularis peroxisome assembly protein 26 0.1263 0.3816 0.3816
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0007 0.0007
Echinococcus granulosus geminin 0.0874 0.2623 0.4139
Echinococcus granulosus tubulin alpha 3 chain 0.1263 0.3816 0.6022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0007 0.0007
Trypanosoma brucei alpha tubulin, putative 0.0503 0.1486 0.2947
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0242 0.0685 0.5675
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0005 0.0005
Brugia malayi G-protein coupled receptor 0.0021 0.0005 0.001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0005 0.0008
Mycobacterium tuberculosis Conserved protein 0.0043 0.0075 0.0592
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Brugia malayi beta-lactamase family protein 0.0043 0.0075 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Toxoplasma gondii thioredoxin reductase 0.0096 0.0235 0.0469
Leishmania major beta tubulin 0.1646 0.4988 1
Echinococcus multilocularis Smad4 0.0042 0.007 0.007
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0017 0.0017
Brugia malayi Cytochrome P450 family protein 0.0055 0.011 0.022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.007 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0067 0.0147 0.0295
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.076 0.2272 0.4553
Echinococcus granulosus tubulin beta 4A class IVa 0.1646 0.4988 0.7873
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0138 0.0217
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Brugia malayi Tubulin alpha chain 0.1263 0.3816 0.7649
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Brugia malayi hypothetical protein 0.0186 0.0511 0.1024
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0025 0.0017 0.0026
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0022 0.0152
Schistosoma mansoni tubulin subunit epsilon 0.0942 0.2831 0.4468
Echinococcus granulosus dnaJ subfamily B 0.0821 0.2458 0.3879
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0039 0.0078
Echinococcus granulosus neuropeptide s receptor 0.0944 0.2835 0.4475
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus granulosus expressed protein 0.0387 0.1128 0.178
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0067 0.0147 0.0147
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.011 0.022
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0092 0.0223 0.0404
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0202 0.0318
Brugia malayi MH1 domain containing protein 0.0023 0.0013 0.0026
Brugia malayi MH2 domain containing protein 0.0617 0.1833 0.3675
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0328 0.0947 0.1887
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0092 0.0223 0.0377
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0192 0.0385
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0015 0.0029
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0005 0.001
Brugia malayi Smad1 0.0042 0.007 0.0141
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0043 0.0072
Echinococcus multilocularis lamin 0.0082 0.0192 0.0192
Echinococcus multilocularis somatostatin receptor 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Trypanosoma brucei protein kinase, putative 0.0103 0.0256 0.0472
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0067 0.0147 0.0232
Brugia malayi Steroid receptor seven-up type 2 0.0067 0.0147 0.0295
Trypanosoma brucei epsilon tubulin 0.0942 0.2831 0.5657
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0223 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0147 0.0295
Schistosoma mansoni tubulin subunit gamma 0.0943 0.2833 0.447
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0283 0.0567
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.01 0.025 0.05
Brugia malayi SPARC precursor 0.0058 0.012 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0283 0.0565
Echinococcus multilocularis tubulin delta chain 0.0412 0.1204 0.1204
Echinococcus granulosus peroxisome assembly protein 26 0.1263 0.3816 0.6022
Echinococcus multilocularis serotonin receptor 0.0021 0.0005 0.0005
Echinococcus multilocularis Regulator of G protein signaling 20 0.0025 0.0017 0.0017
Brugia malayi hypothetical protein 0.0029 0.0031 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0412 0.1204 0.2413
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0075 0.0118
Brugia malayi hypothetical protein 0.0025 0.0017 0.0034
Onchocerca volvulus 0.0043 0.0075 0.0318
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0005 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Brugia malayi PXA domain containing protein 0.0025 0.0017 0.0034
Schistosoma mansoni rab6-interacting 0.01 0.025 0.0394
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0078 0.0078
Echinococcus multilocularis tubulin alpha chain 0.1263 0.3816 0.3816
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0126 0.0253
Echinococcus granulosus neuropeptide receptor 0.0021 0.0005 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0067 0.0147 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0124 0.0247
Toxoplasma gondii transporter, major facilitator family protein 0.0085 0.0203 0.0405
Loa Loa (eye worm) alpha-tubulin 0.1263 0.3816 0.7649
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0075 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0055 0.0109
Schistosoma mansoni histamine h1 receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis tubulin epsilon chain, putative 0.1646 0.4988 1
Echinococcus granulosus orexin receptor type 2 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0283 0.0498
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0036 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Schistosoma mansoni organic anion transporter 0.0085 0.0203 0.032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor A26 0.0944 0.2835 0.2835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0851 0.2553 0.5117
Echinococcus multilocularis beta tubulin 0.1646 0.4988 0.4988
Schistosoma mansoni hypothetical protein 0.0046 0.0082 0.0129
Echinococcus granulosus Tubulin beta 2C chain 0.1646 0.4988 0.7873
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0005 0.001
Echinococcus granulosus tubulin epsilon chain 0.0942 0.2831 0.4468
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Leishmania major beta tubulin 0.1646 0.4988 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0067 0.0147 0.0147
Onchocerca volvulus 0.0021 0.0005 0.0005
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.003 0.003
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0067 0.0147 0.0641
Onchocerca volvulus 0.0085 0.0203 0.089
Brugia malayi Tubulin beta chain 0.0412 0.1204 0.2415
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0666 0.0666
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.0101 0.0132
Schistosoma mansoni nuclear receptor 0.0029 0.0031 0.0049
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0019
Loa Loa (eye worm) tubulin beta-2A chain 0.1646 0.4988 1
Echinococcus granulosus g protein coupled receptor 0.0021 0.0005 0.0008
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.011 0.0149
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Loa Loa (eye worm) RGS-3 protein 0.0025 0.0017 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0147 0.0295
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0147 0.0295
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0147 0.0232
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0793 0.6577
Brugia malayi 6-phosphofructokinase 0.0111 0.0283 0.0567
Brugia malayi Inositol-1 0.0045 0.0078 0.0157
Trypanosoma brucei PAB1-binding protein , putative 0.0102 0.0254 0.0468
Onchocerca volvulus 0.0021 0.0005 0.0005
Trypanosoma cruzi tubulin delta chain 0.0581 0.1724 0.3409
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0039 0.0039
Onchocerca volvulus 0.0021 0.0005 0.0005
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.0235 0.0471
Plasmodium vivax tubulin gamma chain, putative 0.0943 0.2833 0.5672
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0034 0.0008
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0031 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0019
Brugia malayi Dopamine receptor protein 2 0.0021 0.0005 0.001
Echinococcus granulosus tubulin alpha chain 0.1263 0.3816 0.6022
Echinococcus granulosus tubulin alpha chain 0.1263 0.3816 0.6022
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0256 0.0514
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0092 0.0223 0.0432
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0236 0.0373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0034 0.0066
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0005 0.001
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0043 0.0072
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0007 0.0007
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0034 0.0053
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0008
Trichomonas vaginalis abcb9, putative 0.0021 0.0007 0.0013
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0005 0.001
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.012 0.024
Leishmania major beta tubulin 0.1646 0.4988 1
Brugia malayi jmjC domain containing protein 0.0059 0.0122 0.0244
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0025 0.002 0.0039
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.012 0.0239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0263 0.0749 0.0749
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0092 0.0223 0.0351
Loa Loa (eye worm) tubulin beta chain 0.1646 0.4988 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0067 0.0147 0.0295
Brugia malayi beta-lactamase family protein 0.0043 0.0075 0.015
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0051 0.0098 0.0196
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Brugia malayi beta-tubulin, identical 0.1646 0.4988 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.024
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0036 0.0056
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0203 0.0406
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0256 0.0458
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0022 0.0152
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0038 0.0074
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0218
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0055 0.0066
Trichomonas vaginalis taga, putative 0.0021 0.0007 0.0013
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0007 0.0013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0067 0.0147 0.0232
Onchocerca volvulus 0.0085 0.0203 0.089
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0005 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0165 0.0329
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0068 0.0135
Leishmania major beta tubulin 0.1646 0.4988 1
Onchocerca volvulus 0.0082 0.0192 0.0843
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0067 0.0147 0.0232
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.1486 0.2977
Echinococcus multilocularis tubulin alpha chain 0.1263 0.3816 0.3816
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0067 0.0147 0.0147
Brugia malayi nuclear hormone receptor 0.0067 0.0147 0.0295
Onchocerca volvulus 0.0082 0.0192 0.0843
Leishmania major beta tubulin 0.1646 0.4988 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Echinococcus multilocularis tubulin epsilon chain 0.0942 0.2831 0.2831
Echinococcus multilocularis Tubulin alpha 1 chain 0.1263 0.3816 0.3816
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0058 0.0091
Brugia malayi Tubulin beta chain 0.0503 0.1486 0.2978
Schistosoma mansoni smad1 5 8 and 0.0042 0.007 0.0111
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0007 0.0015
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0058 0.0091
Schistosoma mansoni inositol monophosphatase 0.0045 0.0078 0.0124
Loa Loa (eye worm) steroid hormone receptor 0.0067 0.0147 0.0295
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0031 0.0049
Schistosoma mansoni Smad4 0.0042 0.007 0.0111
Toxoplasma gondii protease inhibitor PI2 0.0058 0.012 0.0239
Brugia malayi MH2 domain containing protein 0.0042 0.007 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0147 0.0295
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0055 0.0055
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0075 0.0106
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0122 0.0122
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0043 0.0043
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0126
Echinococcus granulosus Smad4 0.0042 0.007 0.0111
Echinococcus granulosus raf serine:threonine protein kinase 0.0044 0.0077 0.0121
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0022 0.003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0198 0.0547 0.1084
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0147 0.0295
Echinococcus multilocularis expressed protein 0.0387 0.1128 0.1128
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0075 0.0149
Onchocerca volvulus 0.024 0.0679 0.3022
Onchocerca volvulus 0.0058 0.012 0.0519
Giardia lamblia Fructose-bisphosphate aldolase 0.0328 0.0947 0.1851
Brugia malayi hypothetical protein 0.0359 0.1043 0.2091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Schistosoma mansoni hypothetical protein 0.0041 0.0068 0.0107
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0075 0.0592
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0005 0.0008
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0203 0.0406
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0075 0.0118
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma brucei alpha tubulin 0.1263 0.3816 0.7639
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0178 0.1453
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0236 0.0236
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0038 0.0031
Leishmania major beta tubulin 0.1646 0.4988 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0051 0.0098 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0005 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0117 0.0185
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0031 0.0031
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.1486 0.2977
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0192 0.0385
Mycobacterium tuberculosis Cell division protein FtsZ 0.0412 0.1204 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0283 0.0565
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Schistosoma mansoni RAR-like nuclear receptor 0.0067 0.0147 0.0232
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0034 0.0066
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0022 0.0152
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Giardia lamblia Alpha-tubulin 0.1263 0.3816 0.7635
Entamoeba histolytica tubulin alpha-1 chain 0.1263 0.3816 0.7646
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0192 0.0385
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.003 0.0059
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0068 0.0137
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0026
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0043 0.0043
Trichomonas vaginalis tubulin epsilon chain, putative 0.1646 0.4988 1
Brugia malayi MH1 domain containing protein 0.0042 0.007 0.0141
Schistosoma mansoni hypothetical protein 0.0082 0.0192 0.0303
Schistosoma mansoni DNA helicase recq1 0.0029 0.003 0.0047
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0075 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Brugia malayi ecdysone receptor 0.0029 0.0031 0.0062
Schistosoma mansoni lipoxygenase 0.0228 0.0642 0.1013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0068 0.0136
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0005 0.001
Brugia malayi Pax transcription factor protein 2 0.024 0.0679 0.1361
Schistosoma mansoni smad 0.0042 0.007 0.0111
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0051 0.0098 0.0197
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0092 0.0223 0.0377
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0075 0.0592
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.024
Loa Loa (eye worm) inositol-1 0.0045 0.0078 0.0157
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0092 0.0223 0.0404
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0037 0.0037
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0005 0.001
Brugia malayi Dopamine receptor protein 1 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Giardia lamblia Beta tubulin 0.1646 0.4988 1
Schistosoma mansoni inositol monophosphatase 0.0045 0.0078 0.0124
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Echinococcus granulosus RUN 0.01 0.025 0.0394
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0196
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0025 0.0017 0.0026
Echinococcus multilocularis Polycystic kidney disease protein 0.01 0.025 0.025
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Trichomonas vaginalis tubulin beta chain, putative 0.0503 0.1486 0.2977
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0196
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0016 0.0033
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0034 0.0053
Loa Loa (eye worm) alpha-tubulin 0.1263 0.3816 0.7649
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0283 0.2322
Brugia malayi Melatonin receptor type 1A 0.0021 0.0005 0.001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0075 0.0592
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0034 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0513
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0055 0.011 0.088
Trichomonas vaginalis conserved hypothetical protein 0.0412 0.1204 0.2413
Schistosoma mansoni hypothetical protein 0.0266 0.0759 0.1197
Trypanosoma cruzi beta tubulin, putative 0.1646 0.4988 1
Schistosoma mansoni hypothetical protein 0.0874 0.2623 0.4139
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0043 0.0085
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0034 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0147 0.0232
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0055 0.0087
Loa Loa (eye worm) hypoxia-induced factor 1 0.0609 0.1809 0.3627
Schistosoma mansoni alpha tubulin 0.1263 0.3816 0.6022
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0067 0.0147 0.0232
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0025 0.002 0.0039
Echinococcus granulosus expressed conserved protein 0.0186 0.0511 0.0806
Echinococcus multilocularis protein dispatched 1 0.0097 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0005 0.0005
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0092 0.0223 0.0432
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0005 0.0008
Brugia malayi PAS domain containing protein 0.0197 0.0545 0.1093
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0005 0.0005
Toxoplasma gondii alpha-tubulin I, putative 0.1263 0.3816 0.7649
Brugia malayi G-protein coupled receptor 0.0021 0.0005 0.001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0038 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0117 0.0185
Loa Loa (eye worm) hypothetical protein 0.0051 0.0098 0.0197
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0098 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0036 0.007
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0038 0.0003
Mycobacterium tuberculosis Conserved protein 0.0043 0.0075 0.0592
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0031 0.0049
Mycobacterium ulcerans cell division protein FtsZ 0.0412 0.1204 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0147 0.0295
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0036 0.007
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.003 0.0047
Loa Loa (eye worm) hypothetical protein 0.0085 0.0202 0.0404
Schistosoma mansoni hypothetical protein 0.0821 0.2458 0.3879
Echinococcus granulosus tubulin delta chain 0.0412 0.1204 0.1901
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0256 0.0256
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0129 0.0204
Echinococcus multilocularis geminin 0.0874 0.2623 0.2623
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0254 0.0496
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0005 0.0008
Echinococcus granulosus microtubule associated protein 2 0.2085 0.6336 1
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0039 0.0076
Brugia malayi ORL1-like opioid receptor 0.0021 0.0005 0.001
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0051 0.0098 0.0155
Mycobacterium ulcerans putative regulatory protein 0.0146 0.0388 0.3201
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0067 0.0147 0.0232
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0198 0.0547 0.1097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.012 0.024
Schistosoma mansoni transcription factor LCR-F1 0.0186 0.0511 0.0806
Onchocerca volvulus 0.0021 0.0005 0.0005
Echinococcus granulosus axis inhibition protein axin 0.0025 0.0017 0.0026
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0031 0.0049
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Leishmania major beta tubulin 0.1646 0.4988 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis tubulin alpha 1C chain 0.1263 0.3816 0.3816
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0036 0.0036
Schistosoma mansoni amine GPCR 0.0021 0.0005 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0749 0.2238 0.4485
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0031 0.0031
Treponema pallidum fructose-bisphosphate aldolase 0.0328 0.0947 0.7824
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0039 0.0078
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0218 0.0611 0.5054
Plasmodium vivax tubulin alpha chain, putative 0.1263 0.3816 0.7646
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.006 0.0106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis regulator of G protein signaling 3 0.0025 0.0017 0.0017
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0075 0.0592
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.0214 0.0598 0.0944
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0067 0.0147 0.0232
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0031 0.0031
Brugia malayi hypothetical protein 0.0102 0.0254 0.051
Toxoplasma gondii tubulin, putative 0.0027 0.0024 0.0048
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0283 0.0553
Toxoplasma gondii beta-tubulin, putative 0.1646 0.4988 1
Entamoeba histolytica hypothetical protein 0.0186 0.0511 0.1011
Echinococcus multilocularis Tubulin alpha 1 chain 0.1263 0.3816 0.3816
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0051 0.0098 0.0196
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0043 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0256 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0005 0.0005
Schistosoma mansoni follistatin 0.0058 0.012 0.0189
Trypanosoma brucei beta tubulin 0.1646 0.4988 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Plasmodium falciparum alpha tubulin 1 0.1263 0.3816 0.7646
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0144 0.0144
Trypanosoma brucei beta tubulin 0.1646 0.4988 1
Onchocerca volvulus 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0036 0.0028
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0513
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0144 0.0227
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0031 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Plasmodium vivax ataxin-2 like protein, putative 0.0102 0.0254 0.0496
Echinococcus granulosus g protein coupled receptor 0.0021 0.0005 0.0008
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0068
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0078 0.0156
Trichomonas vaginalis tubulin gamma chain, putative 0.0943 0.2833 0.5678
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0078 0.0143
Trypanosoma brucei beta tubulin 0.1646 0.4988 1
Brugia malayi Tubulin gamma chain 0.0943 0.2833 0.5678
Schistosoma mansoni regulator of G protein signaling 0.0026 0.002 0.0031
Onchocerca volvulus 0.0021 0.0005 0.0005
Schistosoma mansoni microtubule-associated protein tau 0.2085 0.6336 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0039 0.0034
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0098 0.533
Echinococcus multilocularis Tubulin beta 2C chain 0.1646 0.4988 0.4988
Leishmania major protein kinase, putative 0.0052 0.0101 0.0189
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0055 0.0039
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0005 0.001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0005 0.0005
Echinococcus multilocularis raf serine:threonine protein kinase 0.0044 0.0077 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0059
Treponema pallidum NADH oxidase 0.0033 0.0043 0.0179
Echinococcus multilocularis regulator of G protein signaling 0.0025 0.0017 0.0017
Onchocerca volvulus Huntingtin homolog 0.0384 0.112 0.4995
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0034 0.0053
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0005 0.0008
Toxoplasma gondii ABC1 family protein 0.0043 0.0075 0.0149
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0031 0.0049
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0005 0.0008
Trypanosoma cruzi tubulin delta chain 0.0581 0.1724 0.3409
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0005 0.0008
Schistosoma mansoni tubulin subunit beta 0.0412 0.1204 0.1901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0165 0.0329
Loa Loa (eye worm) raf kinase 0.0044 0.0077 0.0154
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.016 0.0433 0.3573
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.0179
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.003 0.0047
Onchocerca volvulus 0.01 0.025 0.1099
Echinococcus granulosus tubulin gamma 1 chain 0.0943 0.2833 0.447
Echinococcus granulosus lipoxygenase domain containing protein 0.01 0.025 0.0394
Loa Loa (eye worm) hypothetical protein 0.0384 0.112 0.2245
Trypanosoma cruzi MFS transporter, putative 0.0085 0.0203 0.0337
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0039 0.0076
Echinococcus granulosus regulator of G protein signaling 3 0.0025 0.0017 0.0026
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.012 0.024
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0256 0.05
Echinococcus multilocularis thyroid hormone receptor alpha 0.0067 0.0147 0.0147
Brugia malayi hypothetical protein 0.0025 0.0017 0.0034
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0039 0.0063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Leishmania major hypothetical protein, conserved 0.0043 0.0075 0.0136
Leishmania major protein kinase, putative 0.0052 0.0101 0.0189
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0055 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.0537 0.0847
Loa Loa (eye worm) hypothetical protein 0.0384 0.112 0.2245
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0005 0.0008
Echinococcus granulosus Regulator of G protein signaling 20 0.0025 0.0017 0.0026
Trypanosoma brucei beta tubulin 0.0915 0.2748 0.549
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0126 0.0253
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0007 0.0013
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0658 0.196 0.3929
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0075 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Echinococcus granulosus tubulin alpha chain 0.1263 0.3816 0.6022
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0005 0.0008
Echinococcus granulosus lamin 0.0082 0.0192 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Echinococcus multilocularis tubulin alpha chain 0.1263 0.3816 0.3816
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0039 0.0061
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0015
Echinococcus granulosus Tubulin alpha 1 chain 0.1263 0.3816 0.6022
Brugia malayi CHE-14 protein 0.0085 0.0202 0.0404
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.007 0.0111
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0283 0.0565
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0005 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0016 0.0033
Onchocerca volvulus 0.0029 0.0031 0.0121
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0021 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) doublecortin family protein 0.01 0.025 0.05
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0129 0.0257
Trichomonas vaginalis adenylate cyclase, putative 0.0051 0.0098 0.0196
Trichomonas vaginalis esterase, putative 0.0043 0.0075 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0082 0.0082
Echinococcus multilocularis serotonin receptor 0.0021 0.0005 0.0005
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0036 0.0057
Echinococcus granulosus lipoxygenase domain containing protein 0.01 0.025 0.0394
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0039 0.0039
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0147 0.0232
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0202 0.0318
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0236 0.0373
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0178 0.0343
Treponema pallidum cell division protein FtsZ 0.0412 0.1204 1
Schistosoma mansoni hypothetical protein 0.0082 0.0192 0.0303
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0144 0.0274
Brugia malayi RE15519p 0.0021 0.0005 0.001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0078 0.0476
Echinococcus granulosus Polycystic kidney disease protein 0.01 0.025 0.0394
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0129 0.0204
Echinococcus multilocularis Tubulin beta 2C chain 0.1646 0.4988 0.4988
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0007 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0218 0.0611 0.5054
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0117 0.0185
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0122 0.0192
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.0101 0.0132
Giardia lamblia Gamma tubulin 0.0943 0.2833 0.5653
Echinococcus granulosus smad 0.0042 0.007 0.0111
Schistosoma mansoni multidrug resistance protein 0.0021 0.0007 0.0011
Leishmania major beta tubulin 0.1646 0.4988 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0055 0.0109
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0129 0.0129
Onchocerca volvulus Protein ultraspiracle homolog 0.0067 0.0147 0.0641
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0005 0.0005
Schistosoma mansoni lamin 0.0082 0.0192 0.0303
Brugia malayi 6-phosphofructokinase 0.0111 0.0283 0.0568
Echinococcus granulosus tubulin alpha 1C chain 0.1263 0.3816 0.6022
Plasmodium falciparum tubulin gamma chain 0.0943 0.2833 0.5672
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0005 0.0005
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0283 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0196
Echinococcus multilocularis beta tubulin 0.1646 0.4988 0.4988
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0005 0.001
Echinococcus multilocularis cpg binding protein 0.0095 0.0233 0.0233
Onchocerca volvulus 0.0085 0.0203 0.089
Loa Loa (eye worm) tubulin alpha chain 0.1263 0.3816 0.7649
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Onchocerca volvulus 0.0207 0.0576 0.256
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0008
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0055 0.0087
Giardia lamblia GTOR 0.0092 0.0223 0.0389
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0005 0.0008
Brugia malayi Raf kinase 0.0044 0.0077 0.0154
Brugia malayi MAP kinase sur-1 0.0103 0.0256 0.0514
Onchocerca volvulus 0.0503 0.1486 0.6631
Leishmania major beta tubulin 0.1646 0.4988 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Brugia malayi bHLH-PAS transcription factor 0.0146 0.0388 0.0778
Echinococcus granulosus allatostatin A receptor 0.0021 0.0005 0.0008
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0165 0.0261
Loa Loa (eye worm) hypothetical protein 0.1263 0.3816 0.7649
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0062 0.0099
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0007 0.0013
Loa Loa (eye worm) DR-78 0.0029 0.0031 0.0062
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus granulosus alpha tubulin 0.1263 0.3816 0.6022
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0022 0.0864
Echinococcus multilocularis Niemann Pick C1 protein 0.0198 0.0547 0.0547
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0007 0.0011
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0283 0.0553
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0039 0.0063
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0283 0.0446
Brugia malayi MH1 domain containing protein 0.0023 0.0013 0.0026
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0283 0.0283
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0256 0.0445
Schistosoma mansoni multidrug resistance protein 0.0021 0.0007 0.0011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0256 0.0472
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0031 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi Tubulin alpha-2 chain 0.1263 0.3816 0.7649
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.016 0.0433 0.3573
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0807 0.0807
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0254 0.0441
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0017 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0005 0.0005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0117 0.0117
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0031 0.0049
Loa Loa (eye worm) hypothetical protein 0.066 0.1966 0.3941
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis tubulin beta 1 chain 0.1646 0.4988 0.4988
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0058 0.012 0.024
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0085 0.0203 0.0203
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0075 0.0149
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0807 0.1274
Plasmodium vivax SET domain protein, putative 0.0096 0.0236 0.046
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0063
Plasmodium vivax delta tubulin, putative 0.0412 0.1204 0.2403
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0186 0.0511 0.0511
Echinococcus granulosus tubulin subunit TubB 0.1263 0.3816 0.6022
Onchocerca volvulus 0.0021 0.0005 0.0005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.003
Echinococcus multilocularis tubulin alpha 3 chain 0.1263 0.3816 0.3816
Echinococcus multilocularis tubulin subunit beta 0.1646 0.4988 0.4988
Plasmodium vivax multidomain scavenger receptor, putative 0.01 0.025 0.0486
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0201 0.0557 0.0879
Onchocerca volvulus 0.0085 0.0203 0.089
Giardia lamblia Beta tubulin 0.1646 0.4988 1
Plasmodium falciparum tubulin delta chain, putative 0.0412 0.1204 0.2403
Loa Loa (eye worm) hypothetical protein 0.006 0.0126 0.0253
Brugia malayi hypoxia-induced factor 1 0.0609 0.1809 0.3627
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0218 0.0611 0.5054
Trypanosoma brucei cytochrome P450, putative 0.0055 0.011 0.0176
Echinococcus granulosus neuropeptide receptor A26 0.0944 0.2835 0.4475
Echinococcus granulosus lamin dm0 0.0082 0.0192 0.0303
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0092 0.0223 0.0223
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0075 0.015
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0147 0.0232
Giardia lamblia Alpha-tubulin 0.1263 0.3816 0.7635
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0005 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0057 0.0117 0.0235
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0874 0.2623 0.4139
Brugia malayi tubulin alpha-2 chain 0.1263 0.3816 0.7649
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0129 0.1043
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.007 0.0111
Schistosoma mansoni opsin-like receptor 0.0021 0.0005 0.0008
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0034 0.0053
Brugia malayi Dopamine receptor 0.0021 0.0005 0.001
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0068 0.0136
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Plasmodium vivax tubulin beta chain, putative 0.1646 0.4988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.013 0.0259
Trypanosoma brucei alpha tubulin 0.1263 0.3816 0.7639
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0043 0.0072
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.0125
Toxoplasma gondii beta-1 tubulin, putative 0.1646 0.4988 1
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0005 0.0008
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.0179
Brugia malayi ABC transporter family protein 0.0021 0.0007 0.0015
Schistosoma mansoni aryl hydrocarbon receptor 0.0197 0.0545 0.086
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0283 0.0553
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.011
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0025 0.0017 0.0026
Leishmania major beta tubulin 0.1646 0.4988 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0129 0.0245
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0019
Echinococcus multilocularis axis inhibition protein axin 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0078 0.0086
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0409 0.1196 0.1887
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi glutathione reductase 0.0096 0.0235 0.0471
Loa Loa (eye worm) hypothetical protein 0.0102 0.0254 0.051
Plasmodium falciparum tubulin beta chain 0.1646 0.4988 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0031 0.0031
Trichomonas vaginalis tubulin gamma chain, putative 0.0942 0.2831 0.5675
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0067 0.0147 0.0232
Brugia malayi beta-lactamase 0.0043 0.0075 0.015
Schistosoma mansoni cpg binding protein 0.0095 0.0233 0.0367
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.003
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0005 0.0005
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0005 0.0008
Brugia malayi MH1 domain containing protein 0.0042 0.007 0.0141
Loa Loa (eye worm) tubulin alpha 2 0.0851 0.2553 0.5118
Leishmania major delta tubulin, putative 0.0581 0.1724 0.3447
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0005 0.0005
Brugia malayi nuclear receptor RXR 0.0029 0.0031 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Mycobacterium ulcerans endonuclease IV 0.0077 0.0178 0.1453
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.002 0.0031
Plasmodium vivax tubulin epsilon chain, putative 0.0942 0.2831 0.567
Onchocerca volvulus 0.0021 0.0005 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0031 0.0062
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0007 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0005 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.0067 0.0147 0.0295
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0186 0.0511 0.0806
Echinococcus granulosus Solute carrier organic anion transporter family 0.0085 0.0203 0.032
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0058 0.0116
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0085 0.0203 0.0203
Leishmania major beta tubulin 0.1646 0.4988 1
Leishmania major hypothetical protein, conserved 0.0102 0.0254 0.0496
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0242 0.0685 0.5675
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.011 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0196
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0075 0.0592
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0144 0.0288
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis dnaJ subfamily B 0.0821 0.2458 0.2458
Mycobacterium ulcerans hypothetical protein 0.0043 0.0075 0.0592
Leishmania major zeta tubulin, putative 0.0695 0.2073 0.4148
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0005 0.0008
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0043 0.0087
Schistosoma mansoni tubulin subunit alpha 0.1263 0.3816 0.6022
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0043 0.0085
Brugia malayi neuropeptide F receptor 0.0021 0.0005 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0075 0.0592
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0067 0.0147 0.0295
Brugia malayi Pre-SET motif family protein 0.0096 0.0236 0.0474
Trypanosoma cruzi alpha tubulin, putative 0.1263 0.3816 0.7632
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.003 0.0059
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0078 0.0124
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0039 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0067 0.0147 0.0295
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trichomonas vaginalis tubulin alpha chain, putative 0.1646 0.4988 1
Schistosoma mansoni organic anion transporter 0.0085 0.0203 0.032
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0075 0.0149
Onchocerca volvulus 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0146 0.0388 0.172
Brugia malayi hypothetical protein 0.0384 0.112 0.2245
Brugia malayi Regulator of G protein signaling domain containing protein 0.0025 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0005 0.0008
Onchocerca volvulus 0.0021 0.0005 0.0005
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0151 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0218
Brugia malayi hypothetical protein 0.0038 0.0058 0.0116
Onchocerca volvulus Huntingtin homolog 0.0384 0.112 0.4995
Schistosoma mansoni tubulin subunit alpha 0.0412 0.1204 0.1901
Brugia malayi hypothetical protein 0.0085 0.0203 0.0406
Loa Loa (eye worm) beta-lactamase 0.0043 0.0075 0.015
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0005 0.0008
Plasmodium vivax tubulin alpha chain, putative 0.1263 0.3816 0.7646
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.0235 0.0235
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.016 0.0433 0.3573
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0043 0.0328
Mycobacterium ulcerans beta-lactamase 0.0043 0.0075 0.0592
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0439 0.1287 0.258
Schistosoma mansoni neuropeptide receptor 0.0021 0.0005 0.0008
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0178 0.0357
Onchocerca volvulus 0.015 0.0402 0.1783
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0005 0.0008
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0005 0.001
Brugia malayi putative neuropeptide receptor 0.0021 0.0005 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0055 0.0055
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0059 0.0093
Onchocerca volvulus 0.0043 0.0075 0.0318
Entamoeba histolytica hypothetical protein 0.0186 0.0511 0.1011
Echinococcus granulosus serotonin receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis Tubulin alpha 1 chain 0.1263 0.3816 0.3816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0851 0.2553 0.5118
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0067 0.0147 0.0232
Trichomonas vaginalis tubulin gamma chain, putative 0.0412 0.1204 0.2413
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0513
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0031 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.015 0.0402 0.0807
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0165 0.0329
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0055 0.0096
Onchocerca volvulus 0.0359 0.1043 0.4652
Trypanosoma brucei alpha tubulin 0.1263 0.3816 0.7639
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0144 0.0227
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0068 0.0068
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0242 0.0685 0.5675
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0005 0.0005
Leishmania major beta tubulin 0.1646 0.4988 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0075 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0057 0.0117 0.0185
Echinococcus multilocularis expressed conserved protein 0.0186 0.0511 0.0511
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0666 0.1051
Schistosoma mansoni axis inhibition protein axin 0.0025 0.0017 0.0026
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0218 0.0611 0.5054
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0072
Echinococcus multilocularis jun protein 0.0263 0.0749 0.0749
Trypanosoma brucei beta tubulin 0.1646 0.4988 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0036 0.0072
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Echinococcus granulosus Niemann Pick C1 protein 0.0198 0.0547 0.0864
Loa Loa (eye worm) glutathione reductase 0.0096 0.0235 0.0471
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1263 0.3816 0.7649
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi hypothetical protein 0.0207 0.0576 0.1154
Loa Loa (eye worm) tubulin alpha 2 0.0348 0.1009 0.2022
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0023 0.0037
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0031 0.0062
Brugia malayi hypothetical protein 0.0029 0.0031 0.0062
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0167 0.0264
Trichomonas vaginalis tubulin gamma chain, putative 0.1646 0.4988 1
Echinococcus granulosus tubulin alpha 0.0915 0.2748 0.4338
Brugia malayi bZIP transcription factor family protein 0.0263 0.0749 0.1502
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0067 0.0147 0.0295
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0196
Leishmania major beta tubulin 0.1646 0.4988 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0005 0.0008
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0022 0.0043
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0223 0.0446
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0058 0.0058
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0043 0.0028
Schistosoma mansoni opsin-like receptor 0.0021 0.0005 0.0008
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0031 0.0049
Loa Loa (eye worm) hypothetical protein 0.008 0.0188 0.0376
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Mycobacterium leprae Possible regulatory protein 0.0051 0.0098 0.0788
Trypanosoma cruzi zeta tubulin, putative 0.0695 0.2073 0.4114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0031 0.0049
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0005 0.0008
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0007 0.0011
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.0228 0.0228
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0022 0.0152
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.0228 0.0359
Trypanosoma brucei alpha tubulin 0.1263 0.3816 0.7639
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0122 0.0122
Brugia malayi phosphofructokinase 0.0111 0.0283 0.0567
Trichomonas vaginalis tubulin epsilon chain, putative 0.0412 0.1204 0.2413
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0007 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0025 0.0017 0.0032
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0076 0.0152
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0067 0.0147 0.0147
Trypanosoma cruzi epsilon tubulin, putative 0.0942 0.2831 0.5645
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0183
Echinococcus multilocularis microtubule associated protein 2 0.2085 0.6336 0.6336
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0055 0.0055
Brugia malayi regulator of G-protein signaling egl-10 0.0025 0.0017 0.0034
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0005 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0005 0.0008
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0031 0.0062
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.009 0.0217 0.0343
Echinococcus granulosus bloom syndrome protein 0.0041 0.0068 0.0108
Entamoeba histolytica hypothetical protein 0.0026 0.0022 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0129 0.1043
Trichomonas vaginalis tubulin alpha chain, putative 0.0915 0.2748 0.5509
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) tubulin alpha 2 0.0851 0.2553 0.5118
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.0235 0.0371
Echinococcus granulosus beta-adrenergic receptor kinase 0.0025 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0851 0.2553 0.5118
Mycobacterium leprae Probable lipase LipE 0.0043 0.0075 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0223 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Loa Loa (eye worm) beta-tubulin 0.1646 0.4988 1
Echinococcus granulosus g protein coupled receptor 0.0021 0.0005 0.0008
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0055 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0015
Echinococcus multilocularis follistatin 0.0058 0.012 0.012
Schistosoma mansoni retinoic acid receptor RXR 0.0067 0.0147 0.0232
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0005 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0004 0.0006
Brugia malayi Serotonin receptor 0.0021 0.0005 0.001
Giardia lamblia Delta tubulin 0.0412 0.1204 0.2369
Loa Loa (eye worm) tubulin beta-4 chain 0.1646 0.4988 1
Schistosoma mansoni neuropeptide receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0031 0.0031
Brugia malayi Tubulin alpha chain 0.0412 0.1204 0.2415
Brugia malayi multidrug resistance protein 3 0.0021 0.0007 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0328 0.0947 0.1887
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0254 0.0496
Plasmodium vivax glutathione reductase, putative 0.0096 0.0235 0.0457
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0617 0.1833 0.3675
Trypanosoma brucei tubulin gamma chain 0.0943 0.2833 0.5659
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0007 0.0011
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0147 0.0232
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0068
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0005 0.001
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0043 0.0072
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0078 0.0113
Brugia malayi tubulin alpha chain - mouse 0.1263 0.3816 0.7649
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0017 0.0026
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0126
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0144 0.0218
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0031 0.0049
Schistosoma mansoni biogenic amine receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0036 0.007
Echinococcus multilocularis FTZ F1 alpha 0.0067 0.0147 0.0147
Echinococcus multilocularis lamin dm0 0.0082 0.0192 0.0192
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0038 0.0061
Loa Loa (eye worm) tubulin beta chain 0.0412 0.1204 0.2415
Onchocerca volvulus 0.0021 0.0005 0.0005
Schistosoma mansoni neuropeptide receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0005 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.003 0.0058
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1646 0.4988 0.4988
Onchocerca volvulus 0.01 0.025 0.1099
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0108 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Echinococcus multilocularis tumor protein p63 0.1026 0.3089 0.3089
Toxoplasma gondii beta tubulin 0.1646 0.4988 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0915 0.2748 0.5509
Plasmodium falciparum glutathione reductase 0.0096 0.0235 0.0457
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0005 0.0008
Echinococcus multilocularis tubulin gamma 1 chain 0.0943 0.2833 0.2833
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.012 0.024
Schistosoma mansoni biogenic amine receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0067 0.0147 0.0295
Onchocerca volvulus 0.0021 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.002 0.0031
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0068 0.0135
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0043 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi nuclear receptor NHR-88 0.0029 0.0031 0.0062
Loa Loa (eye worm) nuclear factor I 0.0023 0.0013 0.0026
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0031 0.0121
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0005 0.0008
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0092 0.0223 0.0432
Brugia malayi regulator of G-protein signaling rgs-7 0.0025 0.0017 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0005 0.0005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0144 0.0288
Schistosoma mansoni axis inhibition protein axin 0.0025 0.0017 0.0026
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0178 0.1453
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0013
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0017 0.0026
Mycobacterium tuberculosis Probable reductase 0.0218 0.0611 0.5054
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0283 0.0567
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0236 0.0373
Brugia malayi A-kinase anchor protein 10, precursor 0.0025 0.0017 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0067 0.0147 0.0295
Echinococcus granulosus tumor protein p63 0.1026 0.3089 0.4876
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.012 0.0239
Loa Loa (eye worm) hypothetical protein 0.0359 0.1043 0.2091
Toxoplasma gondii histone lysine methyltransferase SET1 0.0174 0.0474 0.0949
Echinococcus multilocularis tubulin alpha 1C chain 0.1263 0.3816 0.3816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0181 0.0362
Schistosoma mansoni cellular tumor antigen P53 0.015 0.0402 0.0635
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0165 0.0317
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0007 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi tailless protein 0.0029 0.0031 0.0062
Brugia malayi alpha-tubulin 0.1263 0.3816 0.7649
Trichomonas vaginalis helicase, putative 0.002 0.0004 0.0006
Echinococcus multilocularis expressed protein 0.0058 0.012 0.012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Brugia malayi Tubulin beta-1 chain 0.1646 0.4988 1
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0031 0.0049
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0031 0.0121
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0017 0.002
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0141
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0017 0.0026
Schistosoma mansoni hypothetical protein 0.0082 0.0192 0.0303
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0055 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0036 0.007
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0005 0.0008
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.012 0.0239
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.012 0.0239
Loa Loa (eye worm) hypothetical protein 0.0236 0.0666 0.1336
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0236 0.0373
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0078 0.0156
Brugia malayi sulfakinin receptor protein 0.0021 0.0005 0.001
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Echinococcus multilocularis Tubulin beta 2C chain 0.1646 0.4988 0.4988
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0165 0.0288
Loa Loa (eye worm) hypothetical protein 0.0082 0.0192 0.0385
Giardia lamblia Epsilon tubulin 0.0439 0.1287 0.2537
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0036 0.0073
Brugia malayi nuclear receptor NHR-88 0.0067 0.0147 0.0295
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0008
Toxoplasma gondii endonuclease IV APN 0.0077 0.0178 0.0356
Loa Loa (eye worm) PXA domain-containing protein 0.0025 0.0017 0.0034
Onchocerca volvulus 0.0067 0.0147 0.0641
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0007 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0075 0.0592
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.003 0.0059
Echinococcus multilocularis aryl hydrocarbon receptor 0.0051 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Schistosoma mansoni amine GPCR 0.0021 0.0005 0.0008
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0203 0.089
Echinococcus multilocularis musashi 0.0082 0.0192 0.0192
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.003 0.0045
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0034 0.0053
Brugia malayi hypothetical protein 0.01 0.025 0.05
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0007 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0078 0.0156
Echinococcus multilocularis agrin 0.0058 0.012 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0005 0.0008
Echinococcus granulosus Tubulin beta 2C chain 0.1646 0.4988 0.7873
Loa Loa (eye worm) hypothetical protein 0.0256 0.0727 0.1458
Echinococcus granulosus cpg binding protein 0.0095 0.0233 0.0367
Trichomonas vaginalis tubulin epsilon chain, putative 0.1263 0.3816 0.7649
Echinococcus multilocularis neuropeptide s receptor 0.0944 0.2835 0.2835
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0412 0.1204 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.0072
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0005 0.0005
Giardia lamblia Beta tubulin 0.1646 0.4988 1
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0256 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.0228 0.0359
Schistosoma mansoni adenoreceptor 0.0021 0.0005 0.0008
Echinococcus granulosus axis inhibition protein axin 0.0025 0.0017 0.0026
Echinococcus granulosus tubulin alpha chain 0.1263 0.3816 0.6022
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0078 0.0621
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0005 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0513
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0005 0.0008
Brugia malayi Tubulin alpha-2 chain 0.1263 0.3816 0.7649
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0167 0.0167
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.01 0.025 0.025
Schistosoma mansoni agrin 0.0058 0.012 0.0189
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Brugia malayi nuclear receptor RXR 0.0038 0.0058 0.0116
Entamoeba histolytica tubulin family protein 0.1646 0.4988 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Echinococcus multilocularis hypothetical protein 0.1263 0.3816 0.3816
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0107
Schistosoma mansoni tubulin subunit delta 0.0412 0.1204 0.1901
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Loa Loa (eye worm) hypothetical protein 0.0104 0.026 0.0521
Echinococcus granulosus tubulin alpha 1C chain 0.1263 0.3816 0.6022
Echinococcus granulosus tubulin subunit beta 0.1646 0.4988 0.7873
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) pax transcription factor protein 2 0.024 0.0679 0.1361
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Plasmodium falciparum alpha tubulin 2 0.1263 0.3816 0.7646
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0256 0.0445
Brugia malayi follicle stimulating hormone receptor 0.0254 0.0721 0.1446
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0283 0.2322
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0075 0.0592
Brugia malayi CXXC zinc finger family protein 0.009 0.0217 0.0435
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0005 0.001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0055 0.0051
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Trichomonas vaginalis tubulin beta chain, putative 0.1646 0.4988 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0242 0.0685 0.5675
Loa Loa (eye worm) Smad1 0.0042 0.007 0.0141
Trichomonas vaginalis tubulin, putative 0.0503 0.1486 0.2977
Brugia malayi Cell division protein ftsZ 0.0412 0.1204 0.2415
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0005 0.001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0144 0.0245
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0007 0.0013
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0254 0.0441
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0005 0.0008
Schistosoma mansoni alpha tubulin 0.1263 0.3816 0.6022
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0147 0.0232
Schistosoma mansoni hypothetical protein 0.0186 0.0511 0.0806
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi hypothetical protein 0.066 0.1966 0.3941
Leishmania major beta tubulin 0.1646 0.4988 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0196
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0138 0.0217
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0256 0.0445
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0005 0.0005
Leishmania major beta tubulin 0.1646 0.4988 1
Trypanosoma brucei epsilon tubulin 0.0942 0.2831 0.5657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi nuclear hormone receptor 0.0029 0.0031 0.0062
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Brugia malayi hypothetical protein 0.0066 0.0143 0.0288
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Echinococcus granulosus agrin 0.0058 0.012 0.0189
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0085 0.0203 0.0406
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0203 0.089
Leishmania major trypanothione reductase 0.0096 0.0235 0.0457
Echinococcus granulosus regulator of G protein signaling 3 0.0025 0.0017 0.0026
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0055 0.011
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0005 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0067 0.0147 0.0295
Brugia malayi secreted modular calcium-binding protein 1 0.0058 0.012 0.024
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0007 0.0011
Schistosoma mansoni coup transcription factor 0.0067 0.0147 0.0232
Schistosoma mansoni multidrug resistance protein 0.0021 0.0007 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0328
Onchocerca volvulus 0.009 0.0217 0.0954
Brugia malayi ecdysteroid receptor 0.0067 0.0147 0.0295
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0039 0.0006
Loa Loa (eye worm) hypothetical protein 0.0058 0.012 0.024
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0005 0.0005
Echinococcus granulosus ecdysone induced protein 78C 0.0067 0.0147 0.0232
Echinococcus granulosus hypothetical protein 0.0021 0.0005 0.0008
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0074 0.0106
Brugia malayi Cytochrome P450 family protein 0.0055 0.011 0.022
Schistosoma mansoni intermediate filament proteins 0.0082 0.0192 0.0303
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.022 0.0347
Entamoeba histolytica hypothetical protein 0.0186 0.0511 0.1011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0004 0.0006
Schistosoma mansoni polycystin 1-related 0.01 0.025 0.0394
Onchocerca volvulus Bile acid receptor homolog 0.0067 0.0147 0.0641
Echinococcus granulosus aryl hydrocarbon receptor 0.0051 0.0098 0.0155
Mycobacterium tuberculosis Conserved protein 0.0043 0.0075 0.0592
Leishmania major epsilon tubulin, putative 0.0942 0.2831 0.567
Echinococcus multilocularis sex peptide receptor 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0096 0.0236 0.104
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0256 0.0405
Onchocerca volvulus 0.0051 0.0098 0.0423
Echinococcus granulosus sex peptide receptor 0.0021 0.0005 0.0008
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0007 0.0015
Schistosoma mansoni tubulin subunit alpha 0.1263 0.3816 0.6022
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0007 0.0011
Echinococcus multilocularis protein patched 0.0085 0.0202 0.0202
Mycobacterium leprae cell division protein FtsZ 0.0412 0.1204 1
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0005 0.0005
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0203 0.0406
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0283 0.0446
Onchocerca volvulus 0.0021 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0165 0.0329
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0037 0.0059
Schistosoma mansoni alpha tubulin 0.1263 0.3816 0.6022
Brugia malayi AKH receptor 0.0021 0.0005 0.001
Leishmania major beta tubulin 0.1646 0.4988 1
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0202 0.0402
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0283 0.2204
Loa Loa (eye worm) agrin synaptic family protein 0.0058 0.012 0.024
Schistosoma mansoni biogenic amine receptor 0.0021 0.0005 0.0008
Echinococcus granulosus follistatin 0.0058 0.012 0.0189
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0147 0.0147
Toxoplasma gondii LsmAD domain-containing protein 0.0102 0.0254 0.0508
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0007 0.0013
Schistosoma mansoni survival motor neuron protein 0.0048 0.0089 0.0141
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0034
Echinococcus granulosus Tubulin beta 2C chain 0.1646 0.4988 0.7873
Echinococcus multilocularis RUN 0.01 0.025 0.025
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0043 0.2102
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0075 0.0118
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0263 0.0749 0.1183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0147 0.0147
Echinococcus granulosus tubulin alpha 3 chain 0.1263 0.3816 0.6022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0092 0.0223 0.0432
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0031 0.0062
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0031 0.0062
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0058 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0067 0.0147 0.0295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0057 0.0117 0.0185
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0034 0.1547
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0256 0.0513
Loa Loa (eye worm) tubulin alpha-3 chain 0.076 0.2272 0.4554
Echinococcus multilocularis tubulin subunit TubB 0.1263 0.3816 0.3816
Entamoeba histolytica tubulin family protein 0.1646 0.4988 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0008
Brugia malayi Regulator of G protein signaling domain containing protein 0.0025 0.0017 0.0034
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0092 0.0223 0.0351
Schistosoma mansoni single-minded 0.0197 0.0545 0.086
Brugia malayi hypothetical protein 0.01 0.025 0.05
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0005 0.0005
Brugia malayi Niemann-Pick C1 protein precursor 0.0198 0.0547 0.1097
Brugia malayi neuropeptide F receptor 0.0021 0.0005 0.001
Brugia malayi GnHR receptor homolog 0.0021 0.0005 0.001
Schistosoma mansoni myosin xvIII 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.01 0.025 0.05
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0005 0.0005
Loa Loa (eye worm) tubulin alpha-2 chain 0.1263 0.3816 0.7649
Brugia malayi hypothetical protein 0.0021 0.0005 0.001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0256 0.0445
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi G protein-coupled receptor 0.0021 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0129 0.1043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Onchocerca volvulus 0.0021 0.0007 0.0015
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.0101 0.0132
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0022 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0223 0.0445
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.007 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0043 0.0328
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0089 0.0179
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0007 0.0007
Echinococcus granulosus neuropeptide receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0005 0.0005
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0283 0.0446
Trypanosoma brucei epsilon tubulin 0.0915 0.2748 0.549
Echinococcus multilocularis lipoxygenase domain containing protein 0.01 0.025 0.025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0043 0.0328
Schistosoma mansoni nuclear receptor 0.0029 0.0031 0.0049
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0055 0.0096
Brugia malayi nuclear receptor NHR-67 0.0029 0.0031 0.0062
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0005 0.0008
Plasmodium falciparum thioredoxin reductase 0.0096 0.0235 0.0457
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0007 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0006
Plasmodium falciparum thioredoxin reductase 0.0033 0.0043 0.0072
Onchocerca volvulus 0.0029 0.0031 0.0121
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0005 0.0005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0007 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0217 0.0435
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0075 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0178 0.0343
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.1486 0.2977
Brugia malayi prostaglandin transporter 0.0085 0.0203 0.0406
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0005 0.0008
Echinococcus multilocularis axis inhibition protein axin 0.0025 0.0017 0.0017
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0005 0.001
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0202 0.0404
Loa Loa (eye worm) hypothetical protein 0.0096 0.0236 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0036 0.007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0067 0.0147 0.0232
Schistosoma mansoni cpg binding protein 0.0095 0.0233 0.0367
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0034 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0328 0.0947 0.1897
Schistosoma mansoni loxhd1 0.01 0.025 0.0394
Echinococcus granulosus somatostatin receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0005 0.0005
Echinococcus granulosus tubulin beta 1 chain 0.1646 0.4988 0.7873
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0203 0.089
Onchocerca volvulus 0.0749 0.2238 1
Echinococcus granulosus jun protein 0.0263 0.0749 0.1183
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0138 0.0217
Entamoeba histolytica tubulin alpha chain, putative 0.1263 0.3816 0.7646
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Schistosoma mansoni tubulin subunit alpha 0.1263 0.3816 0.6022
Loa Loa (eye worm) CYP4Cod1 0.0055 0.011 0.022
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0254 0.0721 0.1446
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0108 0.0215
Leishmania major beta tubulin 0.1646 0.4988 1
Onchocerca volvulus 0.0085 0.0203 0.089
Schistosoma mansoni amine GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Schistosoma mansoni smad1 5 8 and 0.0042 0.007 0.0111
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.007 0.007
Trypanosoma cruzi tubulin gamma chain 0.0943 0.2833 0.5647
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0017 0.0032
Echinococcus multilocularis regulator of G protein signaling 3 0.0025 0.0017 0.0017
Brugia malayi Thioredoxin reductase 0.0096 0.0235 0.0471
Trichomonas vaginalis tubulin, putative 0.1646 0.4988 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0078 0.0086
Onchocerca volvulus 0.0048 0.0089 0.0383
Loa Loa (eye worm) BEN-1 protein 0.1646 0.4988 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0039
Trichomonas vaginalis tubulin, putative 0.0439 0.1289 0.2582
Trichomonas vaginalis abcb9, putative 0.0021 0.0007 0.0013
Trypanosoma brucei trypanothione reductase 0.0096 0.0235 0.0429
Schistosoma mansoni hypothetical protein 0.0082 0.0192 0.0303
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0283 0.2322
Schistosoma mansoni rab6-interacting 0.01 0.025 0.0394
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0017 0.0026
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0007 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0075 0.0136
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.0101 0.0132
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.0228 0.0456
Loa Loa (eye worm) BEN-1 protein 0.1646 0.4988 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0039 0.0061
Brugia malayi intermediate filament protein 0.0082 0.0192 0.0385
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0503 0.1486 0.2977
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.002 0.0031
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0076 0.0152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Schistosoma mansoni smad1 5 8 and 0.0042 0.007 0.0111
Loa Loa (eye worm) hypothetical protein 0.0077 0.0178 0.0357
Trypanosoma brucei zeta tubulin 0.0695 0.2073 0.413
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0007 0.0013
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0409 0.1196 0.1196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.015
Onchocerca volvulus 0.0021 0.0005 0.0005
Plasmodium falciparum tubulin epsilon chain, putative 0.0942 0.2831 0.567
Echinococcus multilocularis tubulin alpha chain 0.1263 0.3816 0.3816
Mycobacterium ulcerans lipase LipD 0.0043 0.0075 0.0592
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Brugia malayi hypothetical protein 0.0038 0.0058 0.0116
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0077 0.0121
Leishmania major cytochrome p450-like protein 0.0055 0.011 0.0205
Brugia malayi hypothetical protein 0.0085 0.0203 0.0406
Toxoplasma gondii alpha tubulin TUBA1 0.1263 0.3816 0.7649
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.0235 0.0457
Schistosoma mansoni amine GPCR 0.0021 0.0005 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0283 0.0565
Onchocerca volvulus 0.0021 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0064 0.0138 0.0276
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.0235 0.0402
Chlamydia trachomatis endonuclease IV 0.0077 0.0178 1
Schistosoma mansoni zinc finger protein 0.0029 0.0031 0.0049
Echinococcus multilocularis beta adrenergic receptor kinase 0.0025 0.002 0.002
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0025 0.0017 0.0034
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0043 0.0072
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0021 0.0033
Schistosoma mansoni tubulin subunit beta 0.1646 0.4988 0.7873
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma cruzi zeta tubulin, putative 0.0695 0.2073 0.4114
Loa Loa (eye worm) tubulin gamma chain 0.0943 0.2833 0.5678
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0043 0.0015
Onchocerca volvulus 0.0043 0.0075 0.0318
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0034 0.1547
Echinococcus granulosus fmrfamide receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0036 0.0057
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0067 0.0147 0.0147
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0147 0.0295
Brugia malayi Serotonin receptor 0.0021 0.0005 0.001
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.003 0.003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0129 0.1043
Brugia malayi hypothetical protein 0.0236 0.0666 0.1336
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0031 0.0062
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0223 0.0445
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0283 0.0567
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0025 0.002 0.0039
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0055 0.0087
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Onchocerca volvulus 0.0021 0.0005 0.0005
Trypanosoma cruzi epsilon tubulin, putative 0.0942 0.2831 0.5645
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0129 0.0204
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0036 0.0072
Schistosoma mansoni patched 1 0.0085 0.0202 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0067 0.0147 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0093 0.0185
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0005 0.0008
Brugia malayi steroid hormone receptor 0.0067 0.0147 0.0295
Echinococcus granulosus Tubulin alpha 1 chain 0.1263 0.3816 0.6022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0021
Echinococcus granulosus single minded 2 0.0146 0.0388 0.0613
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0005 0.0008
Brugia malayi larval opioid receptor 0.0021 0.0005 0.001
Echinococcus multilocularis smad 0.0042 0.007 0.007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0067 0.0147 0.0232
Echinococcus granulosus Tubulin beta 2C chain 0.1646 0.4988 0.7873
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0025 0.0017 0.0026
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Leishmania major gamma-tubulin 0.0943 0.2833 0.5672
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0007 0.0011
Echinococcus multilocularis tubulin alpha chain 0.1263 0.3816 0.3816
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0004 0.0008
Trichomonas vaginalis tubulin epsilon chain, putative 0.1263 0.3816 0.7649
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0058 0.0073
Plasmodium falciparum LCCL domain-containing protein 0.01 0.025 0.0486
Schistosoma mansoni neuropeptide receptor 0.0021 0.0005 0.0008
Echinococcus multilocularis Tubulin beta 2C chain 0.1646 0.4988 0.4988
Loa Loa (eye worm) hypothetical protein 0.0085 0.0203 0.0406
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0034 0.0099
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0057 0.0117 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0165 0.0329
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0005 0.0005
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0017 0.0017
Onchocerca volvulus 0.0021 0.0005 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.007 0.0141
Schistosoma mansoni lamin 0.0082 0.0192 0.0303
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0075 0.0592
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0085 0.0203 0.032
Trichomonas vaginalis abcb9, putative 0.0021 0.0007 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0218
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0037 0.0075
Echinococcus granulosus beta tubulin 0.1646 0.4988 0.7873
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0064 0.0501
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0581 0.1724 0.3455
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0144 0.0218
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0082 0.0129
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0038 0.0058 0.0116
Echinococcus granulosus beta tubulin 0.1646 0.4988 0.7873
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.003 0.0058
Brugia malayi isocitrate dehydrogenase 0.0032 0.0039 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0067 0.0147 0.0295
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0057 0.0117 0.0117
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0005 0.0008
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0144 0.0274
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.007 0.0111
Trichomonas vaginalis tubulin beta chain, putative 0.1263 0.3816 0.7649
Schistosoma mansoni DNA helicase recq5 0.0029 0.003 0.0047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0218 0.0611 0.5054
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0007 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0031 0.0049
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0062
Echinococcus multilocularis tubulin alpha 3 chain 0.1263 0.3816 0.3816
Schistosoma mansoni smdr2 0.0021 0.0007 0.0011
Onchocerca volvulus 0.0093 0.0228 0.1002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.0235 0.1924
Entamoeba histolytica hypothetical protein 0.0186 0.0511 0.1011
Leishmania major alpha tubulin 0.1263 0.3816 0.7646
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.011 0.0149
Echinococcus multilocularis transfer RNA-Lys 0.0146 0.0388 0.0388
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0005 0.0008
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0039 0.0006
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0036 0.0028
Loa Loa (eye worm) hypothetical protein 0.0067 0.0147 0.0295
Echinococcus multilocularis tubulin alpha 0.0915 0.2748 0.2748
Echinococcus granulosus tubulin alpha chain 0.1263 0.3816 0.6022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Echinococcus multilocularis Tubulin beta 2C chain 0.1646 0.4988 0.4988
Echinococcus granulosus FTZ F1 alpha 0.0067 0.0147 0.0232
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0005 0.0008
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0007 0.0013
Brugia malayi Doublecortin family protein 0.01 0.025 0.05
Trypanosoma brucei zeta tubulin, putative 0.0695 0.2073 0.413
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0236 0.0472
Mycobacterium tuberculosis Probable dehydrogenase 0.0218 0.0611 0.5054
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0126 0.0253
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0078 0.0156
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0283 0.0553
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0031 0.0031
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0007 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Echinococcus granulosus intermediate filament protein 0.0082 0.0192 0.0303
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0138 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0005 0.0005
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0043 0.0085
Echinococcus granulosus Tubulin beta 2C chain 0.1646 0.4988 0.7873
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0122 0.0192
Loa Loa (eye worm) RecQ helicase 0.0041 0.0068 0.0137
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0058 0.0116
Brugia malayi Pre-SET motif family protein 0.0658 0.196 0.3929
Schistosoma mansoni hypothetical protein 0.01 0.025 0.0394
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0064 0.0501
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0058 0.0091
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0067 0.0147 0.0232
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0005 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0075 0.0149
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0005 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0617 0.1833 0.3675
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.001
Trypanosoma brucei tubulin delta chain 0.0581 0.1724 0.3427
Schistosoma mansoni lipoxygenase 0.0409 0.1196 0.1887
Loa Loa (eye worm) tubulin beta-1 chain 0.1646 0.4988 1
Brugia malayi PXA domain containing protein 0.0025 0.0017 0.0034
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0055 0.0087
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0078 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0412 0.1204 0.2413
Echinococcus granulosus Tubulin alpha 1 chain 0.1263 0.3816 0.6022
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0256 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0006
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0098 0.0196
Loa Loa (eye worm) hypothetical protein 0.076 0.2272 0.4554
Brugia malayi MH2 domain containing protein 0.0042 0.007 0.0141
Schistosoma mansoni opsin-like receptor 0.0021 0.0005 0.0008
Schistosoma mansoni jun-related protein 0.0214 0.0598 0.0944
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0075 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0151 0.03
Loa Loa (eye worm) hypothetical protein 0.0093 0.0228 0.0456

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5012 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.5623 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.7308 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.636 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.0588 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 3.6626 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 37.933 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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