Detailed information for compound 1356135

Basic information

Technical information
  • TDR Targets ID: 1356135
  • Name: 2-[[4-(furan-2-ylmethyl)-5-pyridin-3-yl-1,2,4 -triazol-3-yl]sulfanyl]-1-phenylethanone
  • MW: 376.432 | Formula: C20H16N4O2S
  • H donors: 0 H acceptors: 4 LogP: 2.97 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccccc1)CSc1nnc(n1Cc1ccco1)c1cccnc1
  • InChi: 1S/C20H16N4O2S/c25-18(15-6-2-1-3-7-15)14-27-20-23-22-19(16-8-4-10-21-12-16)24(20)13-17-9-5-11-26-17/h1-12H,13-14H2
  • InChiKey: GBFLQRFEPHIUQL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-[[4-(2-furylmethyl)-5-(3-pyridyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenyl-ethanone
  • 2-[[4-(2-furylmethyl)-5-(3-pyridyl)-1,2,4-triazol-3-yl]thio]-1-phenylethanone
  • 2-[[4-(2-furylmethyl)-5-(3-pyridyl)-1,2,4-triazol-3-yl]thio]-1-phenyl-ethanone
  • 2-[[4-(furan-2-ylmethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]-1-phenyl-ethanone
  • MLS000050896
  • SMR000078592
  • ST5412335
  • ZINC01049802
  • 2-{[4-(2-furylmethyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio}-1-phenylethanone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0076 0.03 0.0702
Brugia malayi Immunoglobulin I-set domain containing protein 0.0596 0.4025 0.4024
Echinococcus granulosus tyrosine protein kinase Fyn 0.0113 0.0559 0.0763
Schistosoma mansoni protein kinase 0.0219 0.1321 0.3108
Trypanosoma brucei polo-like protein kinase 0.022 0.1326 1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0096 0.0437 0.0723
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0574 0.4319
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.0812
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0113 0.0559 0.0924
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0187 0.0438
Toxoplasma gondii CMGC kinase, CK2 family 0.0092 0.0407 0.3528
Trypanosoma brucei Pseudokinase, putative 0.0035 0.0002 0.0004
Plasmodium vivax tyrosine kinase-like protein, putative 0.0035 0.0002 0.0004
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0103 0.0491 0.3694
Entamoeba histolytica protein kinase, putative 0.0066 0.0222 0.1664
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0222 0.1341 0.1834
Toxoplasma gondii AGC kinase 0.0103 0.0491 0.4254
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Loa Loa (eye worm) hypothetical protein 0.0095 0.043 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0117 0.0873
Schistosoma mansoni tyrosine kinase 0.0113 0.0559 0.1312
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0196 0.1154 0.1912
Entamoeba histolytica cell division protein kinase 2, putative 0.0154 0.0856 0.6451
Schistosoma mansoni protein tyrosine kinase 0.0035 0.0002 0.0001
Brugia malayi Furin-like cysteine rich region family protein 0.0628 0.425 0.4249
Loa Loa (eye worm) hypothetical protein 0.0037 0.0018 0.0018
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0035 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0463
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0035 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.0031
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK/EGFR protein kinase 0.0628 0.425 0.425
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0103 0.0491 0.3696
Trypanosoma brucei protein kinase, putative 0.0074 0.0284 0.2136
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Echinococcus multilocularis hemicentin 1 0.0035 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0058 0.0165 0.0272
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK/DDR protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0079 0.0318 0.0318
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0081 0.0334 0.0334
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0049 0.01 0.01
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0117 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0063 0.0085
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0002 0.0002
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0603 0.0602
Trichomonas vaginalis STE family protein kinase 0.007 0.0251 0.1882
Leishmania major protein kinase A catalytic subunit isoform 2 0.0103 0.0491 0.3694
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0113 0.0559 0.0924
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0191 0.1121 0.1121
Giardia lamblia Kinase, AGC AKT 0.0109 0.0535 0.4026
Echinococcus multilocularis Glutaredoxin protein 5 0.0072 0.0268 0.0443
Loa Loa (eye worm) TK protein kinase 0.026 0.1613 0.1613
Echinococcus granulosus tyrosine protein kinase csk 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0113 0.0559 0.0763
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.04 0.2618 0.2618
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0263 0.1975
Echinococcus granulosus neuroglian 0.0038 0.0021 0.0027
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Schistosoma mansoni titin 0.0035 0.0003 0.0004
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.0122 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0259 0.0607
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0966 0.7279
Echinococcus multilocularis protein tyrosine kinase 0.0035 0.0002 0.0001
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0035 0.0002 0.0001
Entamoeba histolytica protein kinase, putative 0.0075 0.0292 0.2194
Loa Loa (eye worm) AGC/PKA protein kinase 0.0103 0.0491 0.0491
Brugia malayi RNA, U transporter 1 0.0099 0.0461 0.046
Schistosoma mansoni hypothetical protein 0.0049 0.01 0.0233
Echinococcus granulosus expressed conserved protein 0.0112 0.0552 0.0754
Schistosoma mansoni cell adhesion molecule 0.0038 0.0021 0.0047
Echinococcus multilocularis snurportin 1 0.0372 0.2415 0.4001
Giardia lamblia Kinase, CMGC CDK 0.0154 0.0856 0.6451
Schistosoma mansoni protein kinase C 0.0037 0.0018 0.0041
Onchocerca volvulus 0.0169 0.0966 0.2783
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0064 0.021 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0072 0.0167
Entamoeba histolytica SH2-protein kinase domain containing protein 0.005 0.0109 0.0814
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0047 0.0088 0.0088
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0143 0.0773 0.0772
Plasmodium vivax protein kinase Crk2 0.0154 0.0856 0.7426
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Echinococcus granulosus casein kinase I alpha 0.0061 0.0187 0.0255
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0092 0.0414 0.0684
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0037 0.0014 0.0095
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0066 0.0222 0.0222
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0065 0.0216 0.0356
Brugia malayi Protein kinase domain containing protein 0.0082 0.0336 0.0335
Loa Loa (eye worm) TK/CSK protein kinase 0.0035 0.0002 0.0002
Echinococcus multilocularis protein kinase 0.0035 0.0002 0.0001
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0035 0.0003 0.0012
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0038 0.0021 0.0047
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK/FAK protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) raf kinase 0.0036 0.0009 0.0009
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Plasmodium falciparum protein serine/threonine kinase-1 0.0082 0.0336 0.2906
Brugia malayi P21-Rho-binding domain containing protein 0.0049 0.01 0.0099
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0117 0.0159
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0075 0.0291 0.2189
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0075 0.0291 0.2186
Echinococcus multilocularis c src tyrosine kinase 0.0082 0.0338 0.0559
Schistosoma mansoni growth factor receptor-bound protein 0.0047 0.0088 0.0205
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0063 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.031 0.2331
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0093 0.0419 0.3151
Brugia malayi Protein kinase domain containing protein 0.0185 0.108 0.1079
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0191 0.1121 0.112
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0191 0.1121 0.1533
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0365 0.0365
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Echinococcus multilocularis tyrosine protein kinase Blk 0.0095 0.0429 0.0709
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0196 0.1152 0.8689
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0064 0.0209 0.0284
Echinococcus granulosus MAP kinase activated protein kinase 2 0.04 0.2618 0.3583
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0196 0.1152 0.8689
Loa Loa (eye worm) hypothetical protein 0.0094 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0062 0.0199 0.0199
Echinococcus multilocularis titin 0.004 0.0041 0.0066
Schistosoma mansoni serine/threonine-protein kinase 0.0099 0.046 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Onchocerca volvulus Serine\/threonine kinase homolog 0.022 0.1326 0.3823
Echinococcus granulosus roundabout 2 0.0038 0.0021 0.0027
Echinococcus multilocularis serine:threonine protein kinase 3 0.0256 0.1586 0.2627
Trypanosoma cruzi casein kinase, putative 0.0061 0.0187 0.14
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus multilocularis RNA directed DNA polymerase 0.0042 0.005 0.0081
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0969 0.1604
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0787 0.1849
Brugia malayi ephrin receptor 1 precursor 0.0067 0.0228 0.0227
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0113 0.0559 0.0924
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0096 0.0437 0.0723
Loa Loa (eye worm) hypothetical protein 0.0079 0.0318 0.0318
Schistosoma mansoni tyrosine kinase 0.0113 0.0559 0.1312
Trypanosoma cruzi p21-activated kinase 3, putative 0.0044 0.0065 0.0483
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.005
Schistosoma mansoni tyrosine protein kinase 0.0035 0.0002 0.0001
Leishmania major casein kinase, putative 0.0061 0.0187 0.14
Trypanosoma cruzi casein kinase, delta isoform, putative 0.004 0.0036 0.0262
Brugia malayi Protein kinase domain containing protein 0.0108 0.0522 0.0521
Echinococcus multilocularis protein kinase 0.0035 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Abl 0.0082 0.0338 0.0559
Echinococcus granulosus unc 13 munc13 0.0037 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0372 0.2415 0.568
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0082 0.0336 0.2906
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0065 0.0152
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Brugia malayi Ras association domain family 1 isoform A 0.0036 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.0088 0.0088
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0074 0.0284 0.2134
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0169 0.0966 0.7279
Echinococcus multilocularis 0.0182 0.1057 0.1751
Brugia malayi casein kinase 1, delta 0.0061 0.0187 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0035 0.0002 0.0001
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0264 0.1642 0.1642
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Schistosoma mansoni diacylglycerol kinase theta 0.0036 0.0009 0.0019
Loa Loa (eye worm) AUR protein kinase 0.0196 0.1152 0.1152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1152 0.8689
Schistosoma mansoni unc-13 (munc13) 0.0037 0.0018 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0082 0.034 0.0562
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0284 0.2134
Schistosoma mansoni vav2 0.0071 0.0257 0.0603
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0035 0.0002 0.0001
Schistosoma mansoni protein kinase 0.0056 0.0152 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0072 0.0167
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0037 0.0014 0.0031
Echinococcus granulosus mitogen activated protein kinase 14 0.0153 0.0851 0.1164
Loa Loa (eye worm) hypothetical protein 0.0112 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.006 0.0185 0.0185
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0284 0.2134
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0097 0.0446 0.0609
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0153 0.0851 0.6413
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0152 0.1138
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0082 0.0336 0.2522
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) TK/INSR protein kinase 0.0457 0.3028 0.3028
Echinococcus granulosus roundabout 2 0.0114 0.0569 0.0777
Leishmania major protein kinase, putative 0.0056 0.0152 0.1138
Brugia malayi Protein kinase domain containing protein 0.0064 0.0209 0.0207
Echinococcus granulosus kinase suppressor of Ras 1 0.0035 0.0002 0.0001
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0103 0.0491 0.3696
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0152 0.1142
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.031 0.2331
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni protein kinase 0.0061 0.0187 0.0438
Echinococcus multilocularis NCK adaptor protein 0.0047 0.0088 0.0144
Plasmodium falciparum protein kinase 5 0.0154 0.0856 0.7426
Echinococcus granulosus integrin linked protein kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0108 0.0522 0.0522
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0038 0.0021 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0966 0.7279
Giardia lamblia Kinase, AGC PKA 0.0093 0.0419 0.3151
Loa Loa (eye worm) hypothetical protein 0.0182 0.1052 0.1052
Echinococcus granulosus roundabout 2 0.0038 0.0021 0.0027
Echinococcus multilocularis tyrosine protein kinase shark 0.0064 0.0209 0.0344
Echinococcus multilocularis casein kinase I alpha 0.0061 0.0187 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0002 0.0001
Echinococcus granulosus receptor type guanylyl cyclase 0.0035 0.0002 0.0001
Schistosoma mansoni protein kinase 0.0058 0.0165 0.0386
Loa Loa (eye worm) AUR protein kinase 0.0196 0.1152 0.1152
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0065 0.0216 0.0216
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0154 0.0856 0.0856
Brugia malayi Stress-activated protein kinase jnk-1 0.0264 0.1642 0.1641
Giardia lamblia Kinase, AGC PKA 0.0103 0.0491 0.3694
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0037 0.0018 0.0024
Echinococcus granulosus raf serine:threonine protein kinase 0.0071 0.0259 0.0353
Onchocerca volvulus 0.0037 0.0018 0.0049
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0108 0.0522 0.0864
Echinococcus granulosus dual specificity 0.0115 0.0574 0.0784
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0038 0.0021 0.0033
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus granulosus mitogen activated protein kinase 0.0074 0.0284 0.0388
Echinococcus granulosus tyrosine protein kinase otk 0.0035 0.0003 0.0003
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0045 0.0072 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0041 0.0094
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0103 0.0491 0.3694
Loa Loa (eye worm) hypothetical protein 0.0146 0.0795 0.0795
Onchocerca volvulus 0.0078 0.031 0.0891
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0108 0.0522 0.0713
Loa Loa (eye worm) hypothetical protein 0.0086 0.0365 0.0365
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0117 0.0159
Entamoeba histolytica PH domain containing protein kinase, putative 0.0099 0.046 0.3464
Schistosoma mansoni tyrosine kinase 0.0409 0.2685 0.6316
Loa Loa (eye worm) hypothetical protein 0.0253 0.1565 0.1565
Giardia lamblia Kinase, CMGC GSK 0.0169 0.0966 0.7279
Trypanosoma cruzi aurora B kinase, putative 0.0196 0.1152 0.8689
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1152 0.8689
Echinococcus multilocularis insulin receptor 0.0457 0.3028 0.5017
Echinococcus granulosus rho-associated protein kinase 1 0.0474 0.3148 0.4308
Schistosoma mansoni protein kinase 0.0219 0.1321 0.3108
Echinococcus multilocularis Rac GTPase activating protein 1 0.0036 0.0009 0.0013
Schistosoma mansoni tyrosine kinase 0.0457 0.3028 0.7123
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0093 0.0419 0.0693
Schistosoma mansoni growth factor receptor-bound protein 0.0047 0.0088 0.0205
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0035 0.0002 0.0001
Brugia malayi Protein kinase domain containing protein 0.0064 0.0208 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0856 0.2012
Trichomonas vaginalis STE family protein kinase 0.0075 0.0291 0.2186
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0082 0.0336 0.2522
Entamoeba histolytica protein kinase, putative 0.0185 0.108 0.8142
Echinococcus multilocularis protein kinase c epsilon type 0.0145 0.0789 0.1306
Leishmania major protein kinase A catalytic subunit isoform 1 0.0103 0.0491 0.3694
Echinococcus granulosus tyrosine protein kinase Src64B 0.0113 0.0559 0.0763
Loa Loa (eye worm) hypothetical protein 0.0067 0.0233 0.0233
Brugia malayi serine/threonine-protein kinase 6 0.0196 0.1152 0.1151
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0038 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0522 0.1226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0079 0.0318 0.0317
Schistosoma mansoni hypothetical protein 0.0043 0.0063 0.0145
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Echinococcus multilocularis FL cytokine receptor 0.0035 0.0002 0.0001
Brugia malayi map kinase activated protein kinase protein 2 0.04 0.2618 0.2618
Echinococcus granulosus Protein kinase C brain isozyme 0.0186 0.1087 0.1487
Echinococcus granulosus tyrosine kinase 0.0095 0.0429 0.0586
Echinococcus granulosus casein kinase I delta 0.0061 0.0187 0.0255
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0072 0.0268 0.0366
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.0122 0.0166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0049 0.0104 0.0242
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0154 0.0856 0.0856
Echinococcus granulosus serine/threonine protein kinase 0.0099 0.046 0.0629
Trypanosoma brucei cdc2-related kinase 3 0.0154 0.0856 0.6453
Schistosoma mansoni tyrosine kinase 0.0204 0.1211 0.2849
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0035 0.0002 0.0004
Brugia malayi putative serine/threonine kinase SADA gamma 0.0045 0.0072 0.0071
Schistosoma mansoni tyrosine kinase 0.0082 0.0338 0.0793
Trypanosoma brucei rac serine-threonine kinase, putative 0.0185 0.108 0.8142
Echinococcus granulosus serine:threonine protein kinase N2 0.0108 0.0522 0.0713
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0153 0.0851 0.6413
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0169 0.0966 0.227
Brugia malayi probable protein kinase 0.0118 0.0596 0.0595
Echinococcus granulosus serine:threonine protein kinase PLK1 0.022 0.1326 0.1814
Schistosoma mansoni tyrosine kinase 0.0064 0.0209 0.0488
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0035 0.0003 0.0003
Schistosoma mansoni vam6/vps39 related 0.0037 0.0014 0.0031
Brugia malayi protein kinase C II. 0.0145 0.0789 0.0788
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Echinococcus multilocularis serine:threonine protein kinase N2 0.0108 0.0522 0.0864
Echinococcus granulosus insulin growth factor 1 receptor beta 0.046 0.3046 0.4168
Schistosoma mansoni nephrin 0.0096 0.0438 0.1029
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0002 0.0001
Trypanosoma cruzi casein kinase, putative 0.0061 0.0187 0.14
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0146 0.0797 0.0796
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0115 0.0574 0.0574
Echinococcus granulosus insulin receptor 0.0457 0.3028 0.4143
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0115 0.0574 0.4319
Echinococcus granulosus c-Jun N-terminal kinases 0.0264 0.1642 0.2246
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0113 0.0559 0.0924
Brugia malayi Variant SH3 domain containing protein 0.0047 0.0088 0.0087
Echinococcus granulosus tyrosine protein kinase Src42A 0.006 0.0179 0.0244
Leishmania major casein kinase II, putative 0.0092 0.0407 0.3063
Onchocerca volvulus 0.0474 0.3148 0.9082
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0365 0.2368 0.3241
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Loa Loa (eye worm) TK/Met protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni cell adhesion molecule 0.0035 0.0003 0.0004
Giardia lamblia Kinase, CAMK CAMKL 0.0045 0.0072 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.022 0.1326 0.3119
Brugia malayi P38 map kinase family protein 2 0.0153 0.0851 0.085
Trypanosoma brucei protein kinase, putative 0.0056 0.0152 0.1142
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0208 0.1555
Brugia malayi protein kinase C3,putative 0.0144 0.0783 0.0782
Entamoeba histolytica hypothetical protein 0.0049 0.01 0.0744
Echinococcus multilocularis twitchin 0.0038 0.0023 0.0036
Plasmodium falciparum tyrosine kinase-like protein 0.0035 0.0002 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0856 0.6451
Brugia malayi diacylglycerol kinase 0.0036 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0035 0.0002 0.0002
Toxoplasma gondii protein kinase 0.0035 0.0002 0.0004
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0153 0.0851 0.6415
Brugia malayi Temporarily assigned gene name protein 59 0.0037 0.0014 0.0013
Loa Loa (eye worm) AGC/PKA protein kinase 0.0103 0.0491 0.0491
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0113 0.0559 0.0763
Echinococcus multilocularis myosin iiia 0.0075 0.0291 0.0481
Echinococcus granulosus myotubularin protein 13 0.0042 0.005 0.0067
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0154 0.0856 0.7426
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0035 0.0002 0.0001
Schistosoma mansoni rap gtpase-activating protein 0.0037 0.0014 0.0031
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0035 0.0003 0.0004
Loa Loa (eye worm) RasGEF domain-containing protein 0.0036 0.0009 0.0009
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0058 0.0165 0.0165
Schistosoma mansoni protein kinase C mu 0.0143 0.0773 0.1818
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Echinococcus multilocularis calcium activated potassium channel 0.0053 0.0132 0.0217
Entamoeba histolytica protein kinase, putative 0.0092 0.0414 0.3113
Loa Loa (eye worm) hypothetical protein 0.0112 0.0551 0.0551
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0103 0.0491 0.4254
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0096 0.0437 0.0597
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0014
Schistosoma mansoni neuroglian 0.0038 0.0021 0.0047
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0154 0.0856 0.6451
Echinococcus granulosus tyrosine protein kinase Blk 0.0095 0.0429 0.0586
Plasmodium falciparum serine/threonine protein kinase, putative 0.0196 0.1152 1
Onchocerca volvulus 0.0467 0.3096 0.8931
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0059 0.0172 0.0172
Echinococcus granulosus dual specificity protein kinase clk2 0.0082 0.0336 0.0458
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0049 0.01 0.0164
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1431 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0277 0.2396
Echinococcus multilocularis PAK box P21 Rho binding 0.007 0.0251 0.0414
Echinococcus multilocularis cyclin dependent kinase 0.0154 0.0856 0.1417
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.0407 0.3063
Echinococcus multilocularis cyclin dependent kinase 1 0.0154 0.0856 0.1417
Echinococcus multilocularis serine:threonine protein kinase 38 0.0108 0.0522 0.0864
Giardia lamblia Kinase, CMGC CDK 0.0154 0.0856 0.6451
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0037 0.0014 0.0031
Echinococcus multilocularis tyrosine kinase 0.0064 0.0209 0.0344
Echinococcus multilocularis ephrin type A receptor 4 A 0.0102 0.0483 0.0799
Brugia malayi Protein kinase domain containing protein 0.0186 0.1081 0.108
Plasmodium falciparum glycogen synthase kinase 3 0.0169 0.0966 0.8378
Echinococcus granulosus epidermal growth factor receptor 0.0409 0.2685 0.3674
Echinococcus multilocularis casein kinase i 0.0061 0.0187 0.0308
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0277 0.0649
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0146 0.0795 0.0795
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0074 0.0284 0.2134
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0113 0.0559 0.0924
Echinococcus granulosus serine:threonine protein kinase 3 0.0256 0.1586 0.2169
Echinococcus granulosus cyclin dependent kinase 1 0.0154 0.0856 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Trypanosoma cruzi polo-like protein kinase, putative 0.022 0.1326 1
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0491 0.3694
Echinococcus multilocularis tyrosine protein kinase pr2 0.0035 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0035 0.0003 0.0012
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0045 0.0072 0.0617
Onchocerca volvulus 0.0064 0.0209 0.0597
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Toxoplasma gondii diacylglycerol kinase, putative 0.0036 0.0009 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.022 0.1326 1
Echinococcus granulosus PAK box P21 Rho binding 0.0049 0.01 0.0136
Entamoeba histolytica hypothetical protein 0.0115 0.0574 0.4319
Brugia malayi Protein kinase domain containing protein 0.0108 0.0522 0.0521
Trypanosoma brucei cdc2-related kinase 1 0.0154 0.0856 0.6453
Brugia malayi RhoGEF domain containing protein 0.0036 0.0009 0.0008
Giardia lamblia Kinase, CMGC MAPK 0.0074 0.0284 0.2134
Echinococcus granulosus protein kinase C gamma type 0.015 0.083 0.1134
Echinococcus multilocularis tyrosine protein kinase csk 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK/ALK protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0208
Echinococcus multilocularis roundabout 2 0.0114 0.0569 0.0941
Loa Loa (eye worm) hypothetical protein 0.0035 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0035 0.0002 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0132 0.0987
Echinococcus multilocularis hemicentin 1 0.0035 0.0003 0.0003
Echinococcus multilocularis serine:threonine protein kinase 0.0064 0.0208 0.0342
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0092 0.0414 0.0565
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0035 0.0002 0.0001
Trichomonas vaginalis STE family protein kinase 0.0092 0.0414 0.3113
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.005
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0038 0.0021 0.0033
Brugia malayi Protein kinase domain 0.0092 0.0414 0.0413
Echinococcus granulosus peroxidasin 0.0035 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0122 0.0623 0.0623
Loa Loa (eye worm) hypothetical protein 0.0045 0.0072 0.0072
Trichomonas vaginalis STE family protein kinase 0.0092 0.0414 0.3113
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0196 0.1152 0.1576
Echinococcus multilocularis protein kinase shaggy 0.0169 0.0966 0.1599
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0522 0.3929
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0169 0.0966 0.0966
Echinococcus multilocularis epidermal growth factor receptor 0.0628 0.425 0.7044
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.048 0.1126
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0375 0.2435 0.5728
Trypanosoma brucei Flagellum attachment zone protein 20 0.0035 0.0002 0.0004
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0035 0.0002 0.0002
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.046 0.3046 0.5047
Brugia malayi protein-tyrosine kinase 0.0095 0.0429 0.0428
Echinococcus multilocularis protein kinase c eta type 0.0036 0.0009 0.0013
Leishmania major protein kinase, putative 0.0082 0.0336 0.2522
Entamoeba histolytica protein kinase, putative 0.0196 0.1152 0.8689
Schistosoma mansoni protein kinase 0.0092 0.0414 0.0972
Schistosoma mansoni cell adhesion molecule 0.0097 0.0448 0.1053
Echinococcus multilocularis Diacylglycerol kinase theta 0.0036 0.0009 0.0013
Echinococcus multilocularis natriuretic peptide receptor 1 0.0035 0.0002 0.0001
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1054 0.7306 1
Onchocerca volvulus 0.0122 0.0623 0.1793
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0061 0.0187 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0041 0.004
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0856 0.6451
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0169 0.0966 0.7279
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0037 0.0018 0.0029
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0093 0.0419 0.0572
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0058 0.0165 0.0224
Onchocerca volvulus Tyrosine kinase homolog 0.0519 0.3466 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0047 0.0088 0.0205
Echinococcus multilocularis rac serine:threonine kinase 0.0099 0.046 0.0761
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0152 0.1138
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.1152 0.271
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0095 0.043 0.0588
Plasmodium falciparum tyrosine kinase-like protein 0.0035 0.0002 0.0004
Loa Loa (eye worm) TK/ABL protein kinase 0.0064 0.0209 0.0209
Onchocerca volvulus 0.0086 0.0365 0.105
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Onchocerca volvulus 0.0067 0.0233 0.0668
Leishmania major protein kinase, putative 0.0082 0.0336 0.2522
Echinococcus granulosus casein kinase i 0.0061 0.0187 0.0255
Echinococcus multilocularis tyrosine protein kinase HCK 0.0066 0.0222 0.0366
Loa Loa (eye worm) TK/RYK protein kinase 0.0035 0.0002 0.0002
Onchocerca volvulus 0.0064 0.0209 0.0597
Brugia malayi Hr1 repeat family protein 0.0108 0.0522 0.0521
Entamoeba histolytica casein kinase 1, putative 0.0061 0.0187 0.14
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0058 0.0165 0.0224
Trypanosoma cruzi cdc2-related kinase 1 0.0154 0.0856 0.6451
Echinococcus granulosus calcium activated potassium channel 0.0053 0.0132 0.018
Echinococcus multilocularis heat shock protein 70 0.0035 0.0002 0.0001
Brugia malayi C1-like domain containing protein 0.0143 0.0773 0.0772
Schistosoma mansoni unc-13 (munc13) 0.0037 0.0018 0.0041
Entamoeba histolytica diacylglycerol kinase, putative 0.0036 0.0009 0.0056
Entamoeba histolytica protein kinase, putative 0.0075 0.0292 0.2194
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0092 0.0414 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.04 0.2618 0.616
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0086 0.0371 0.2791
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0115 0.0574 0.4319
Echinococcus multilocularis tyrosine protein kinase Srms 0.0095 0.0429 0.0709
Entamoeba histolytica protein kinase, putative 0.0035 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0077 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0125 0.0646 0.0646
Echinococcus multilocularis casein kinase ii subunit alpha 0.0092 0.0407 0.0673
Brugia malayi Peroxidasin 0.0035 0.0005 0.0003
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0035 0.0002 0.0001
Echinococcus granulosus casein kinase ii subunit alpha 0.0092 0.0407 0.0556
Echinococcus multilocularis tyrosine protein kinase 0.0035 0.0002 0.0001
Echinococcus multilocularis peroxidasin 0.0035 0.0005 0.0006
Brugia malayi hypothetical protein 0.0037 0.0014 0.0013
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0075 0.0291 0.2186
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0103 0.0491 0.3696
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Plasmodium vivax unspecified product 0.0092 0.0407 0.3528
Entamoeba histolytica hypothetical protein 0.0049 0.01 0.0744
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.067
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0074 0.0284 0.2134
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0284 0.2134
Entamoeba histolytica protein kinase, putative 0.0061 0.0187 0.1402
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus granulosus protein kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0014
Echinococcus multilocularis protein kinase c iota type 0.023 0.1403 0.2324
Echinococcus multilocularis serine:threonine protein kinase N2 0.0108 0.0522 0.0864
Echinococcus granulosus protein kinase 0.0081 0.0334 0.0456
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0074 0.0284 0.2134
Echinococcus granulosus activated cdc42 kinase 1 0.0035 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0522 0.1226
Echinococcus multilocularis neuroglian 0.0038 0.0021 0.0033
Trypanosoma cruzi Protein kinase B 0.0099 0.046 0.3464
Echinococcus multilocularis protein dispatched 1 0.0058 0.0169 0.0278
Echinococcus multilocularis nervana 2 0.0072 0.0268 0.0443
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0113 0.0559 0.0763
Echinococcus multilocularis expressed conserved protein 0.0112 0.0552 0.0913
Brugia malayi serine/threonine-protein kinase PAK 7 0.0414 0.2717 0.2716
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0082 0.0336 0.0336
Brugia malayi Variant SH3 domain containing protein 0.0047 0.0088 0.0087
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0072 0.0267 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0072 0.0167
Schistosoma mansoni hypothetical protein 0.0036 0.0009 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.022 0.1326 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.0169 0.0966 0.8378
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0574 0.1348
Echinococcus multilocularis Immunoglobulin 0.0076 0.03 0.0495
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0284 0.0666
Toxoplasma gondii casein kinase I 0.0061 0.0187 0.1615
Loa Loa (eye worm) AGC/NDR protein kinase 0.0108 0.0522 0.0522
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0365 0.2368 0.3924
Echinococcus multilocularis N chimaerin 0.0065 0.0216 0.0356
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0037 0.0014 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0437 0.1027
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0092 0.0414 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0132 0.0309
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0169 0.0966 0.132
Echinococcus multilocularis 0.0081 0.0334 0.0552
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0092 0.0414 0.0565
Onchocerca volvulus 0.0064 0.0209 0.0597
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0014
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0044 0.0065 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1152 0.8689
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Entamoeba histolytica protein kinase, putative 0.0169 0.0966 0.7279
Entamoeba histolytica hypothetical protein 0.0035 0.0003 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Plasmodium vivax protein kinase, putative 0.004 0.0039 0.0333
Echinococcus granulosus protein kinase c epsilon type 0.0145 0.0789 0.1078
Echinococcus multilocularis lachesin 0.0035 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0132 0.0309
Schistosoma mansoni tyrosine kinase 0.0375 0.2435 0.5728
Echinococcus multilocularis death associated protein kinase 1 0.0877 0.6033 1
Giardia lamblia Kinase, CK1 Casein kinase 0.0061 0.0187 0.14
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Echinococcus multilocularis raf serine:threonine protein kinase 0.0071 0.0259 0.0427
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0563 0.4242
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0061 0.0187 0.0255
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.022 0.1326 0.1326
Schistosoma mansoni hypothetical protein 0.0049 0.0104 0.0242
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0038 0.0021 0.0033
Brugia malayi Variant SH3 domain containing protein 0.0065 0.0216 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Echinococcus multilocularis myotubularin protein 13 0.0042 0.005 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0787 0.1849
Plasmodium vivax serine/threonine kinase-1, putative 0.0082 0.0336 0.2906
Entamoeba histolytica protein kinase domain containing protein 0.0196 0.1152 0.8689
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0092 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0146 0.0797 0.0797
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Brugia malayi STE20-like kinase MST 0.0256 0.1586 0.1585
Brugia malayi serine/threonine protein kinase 6 0.0196 0.1152 0.1151
Brugia malayi Protein kinase domain containing protein 0.0197 0.1164 0.1163
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Schistosoma mansoni kinase 0.0122 0.0624 0.1465
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0038 0.0021 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0277 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.015 0.0829 0.0829
Echinococcus multilocularis tyrosine protein kinase csk 0.0035 0.0002 0.0001
Echinococcus granulosus growth factor receptor bound protein 2 0.0047 0.0088 0.0119
Echinococcus granulosus fibroblast growth factor receptor 4 0.0243 0.1492 0.2041
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0061 0.0187 0.14
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0036 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0103 0.0491 0.0491
Echinococcus multilocularis mitogen activated protein kinase 11 0.0153 0.0851 0.1409
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0035 0.0002 0.0001
Loa Loa (eye worm) AGC/PKN protein kinase 0.0108 0.0522 0.0522
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0037 0.0014 0.0098
Echinococcus multilocularis receptor type guanylyl cyclase 0.0035 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0113 0.0559 0.0924
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0196 0.1152 0.8689
Echinococcus granulosus activin receptor type 0.0056 0.0152 0.0207
Echinococcus granulosus aurora kinase A 0.0196 0.1152 0.1576
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0082 0.0336 0.2522
Echinococcus multilocularis mitogen activated protein kinase 14 0.0153 0.0851 0.1409
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0035 0.0002 0.0001
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0035 0.0002 0.0001
Brugia malayi CHE-14 protein 0.0051 0.0117 0.0116
Plasmodium vivax casein kinase 1, putative 0.0061 0.0187 0.1615
Entamoeba histolytica cell division protein kinase 2, putative 0.0154 0.0856 0.6451
Loa Loa (eye worm) CDC7 protein kinase 0.0078 0.031 0.031
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0277 0.2079
Echinococcus granulosus ephrin type A receptor 4 A 0.0102 0.0483 0.066
Onchocerca volvulus 0.004 0.0036 0.01
Plasmodium falciparum serine/threonine protein kinase KIN 0.0045 0.0072 0.0617
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0277 0.0378
Brugia malayi MAP kinase sur-1 0.0074 0.0284 0.0283
Echinococcus granulosus lachesin 0.0035 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0457 0.3028 0.7123
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.1164 0.2737
Trypanosoma brucei SNF1-related protein kinases, putative 0.0045 0.0072 0.0536
Brugia malayi cell division control protein 2 homolog 0.0154 0.0856 0.0855
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0061 0.0187 0.0309
Echinococcus multilocularis CDC7 cell division cycle 7 0.0078 0.031 0.0513
Entamoeba histolytica protein kinase, putative 0.018 0.1039 0.7829
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0115 0.0576 0.4338
Echinococcus granulosus activated cdc42 kinase 1 0.0035 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0966 0.7279
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0042 0.005 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0797 0.1873
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0219 0.1321 0.2189
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.004 0.0041 0.0041
Echinococcus granulosus snurportin 1 0.0372 0.2415 0.3304
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0035 0.0003 0.0003
Onchocerca volvulus 0.0064 0.0209 0.0597
Entamoeba histolytica casein kinase, putative 0.0061 0.0187 0.14
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0522 0.3929
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0966 0.7279
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0045 0.0072 0.0536
Echinococcus granulosus epidermal growth factor receptor 0.0628 0.425 0.5816
Echinococcus granulosus hypothetical protein 0.006 0.0185 0.0252
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0108 0.0522 0.0713
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0092 0.0407 0.3528
Loa Loa (eye worm) hypothetical protein 0.0078 0.0307 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0437 0.1027
Toxoplasma gondii AGC kinase 0.018 0.1039 0.9011
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0082 0.0336 0.2522
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Echinococcus granulosus tyrosine protein kinase Lyn 0.0134 0.0709 0.097
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0061 0.0187 0.0187
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0603 0.0824
Loa Loa (eye worm) hypothetical protein 0.0133 0.0705 0.0705
Echinococcus granulosus tyrosine protein kinase Fyn 0.0113 0.0559 0.0763
Trypanosoma cruzi cdc2-related kinase 3 0.0154 0.0856 0.6451
Entamoeba histolytica p21-activated kinase 0.0098 0.0455 0.3426
Echinococcus granulosus protein kinase c eta type 0.0036 0.0009 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0038 0.0025 0.0181
Trypanosoma cruzi casein kinase, putative 0.0061 0.0187 0.14
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0103 0.0491 0.049
Loa Loa (eye worm) hypothetical protein 0.0151 0.0831 0.0831
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.0812
Echinococcus multilocularis activin receptor type 0.0056 0.0152 0.0251
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Echinococcus granulosus casein kinase I alpha 0.0061 0.0187 0.0255
Onchocerca volvulus 0.0061 0.0187 0.0535
Giardia lamblia Kinase, NEK 0.0129 0.0678 0.5109
Leishmania major protein kinase A catalytic subunit 0.0103 0.0491 0.3694
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0349 0.2251 0.5296
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0196 0.1152 1
Echinococcus granulosus twitchin 0.0114 0.0571 0.078
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0267 0.2005
Schistosoma mansoni protein kinase 0.0118 0.0596 0.1401
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0064 0.0209 0.1563
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Echinococcus multilocularis casein kinase I delta 0.0061 0.0187 0.0308
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0153 0.0851 0.6413
Brugia malayi phosphoinositide-dependent protein kinase I 0.0072 0.0267 0.0266
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Echinococcus multilocularis tyrosine protein kinase csk 0.0035 0.0002 0.0001
Echinococcus granulosus tyrosine protein kinase HCK 0.0066 0.0222 0.0302
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase Srms 0.0064 0.0209 0.0284
Onchocerca volvulus 0.0041 0.0047 0.0132
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0049 0.01 0.0136
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0074 0.0284 0.2134
Giardia lamblia Kinase, NEK 0.0129 0.0678 0.5109
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0035 0.0002 0.0002
Entamoeba histolytica casein kinase, putative 0.0092 0.0407 0.3063
Schistosoma mansoni septate junction protein 0.0035 0.0003 0.0004
Echinococcus multilocularis mitogen activated protein kinase 0.0074 0.0284 0.0469
Brugia malayi Casein kinase II, alpha chain 0.0092 0.0407 0.0406
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0187 0.0438
Giardia lamblia Kinase, PLK 0.022 0.1326 1
Brugia malayi Protein kinase domain containing protein 0.0064 0.0209 0.0207
Echinococcus multilocularis activated cdc42 kinase 1 0.0035 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.031 0.2331
Giardia lamblia Aurora kinase 0.0196 0.1152 0.8689
Brugia malayi Pleckstrin Homology Domain 0.0042 0.005 0.0049
Entamoeba histolytica serine/threonine protein kinase, putative 0.022 0.1326 1
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.3148 0.7407
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0145 0.0789 0.0789
Brugia malayi intracellular kinase 0.0169 0.0966 0.0965
Brugia malayi Protein kinase domain containing protein 0.0154 0.0856 0.0855
Entamoeba histolytica protein kinase, putative 0.0115 0.0574 0.4319
Echinococcus granulosus retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0035 0.0002 0.0001
Entamoeba histolytica PH domain containing protein kinase, putative 0.0109 0.0532 0.4006
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0074 0.0284 0.2136
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0065 0.0216 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0491 0.1153
Trypanosoma brucei Casein kinase II 0.0092 0.0407 0.3066
Loa Loa (eye worm) hypothetical protein 0.0094 0.0423 0.0423
Schistosoma mansoni protein kinase C mu 0.0036 0.0009 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0023 0.0051
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0191 0.1121 0.1856
Echinococcus granulosus tyrosine kinase 0.0035 0.0002 0.0001
Schistosoma mansoni vesicular amine transporter 0.0076 0.03 0.0702
Loa Loa (eye worm) hypothetical protein 0.0035 0.0001 0.0001
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0349 0.2251 0.2251
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0277 0.5
Loa Loa (eye worm) AUR protein kinase 0.0196 0.1152 0.1152
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0603 0.4543
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus multilocularis casein kinase I alpha 0.0061 0.0187 0.0308
Toxoplasma gondii AGC kinase 0.0103 0.0491 0.4254
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0277 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0491 0.1153
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0169 0.0966 0.0966
Schistosoma mansoni protein kinase 0.0196 0.1152 0.271
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0045 0.0072 0.0118
Echinococcus multilocularis tyrosine protein kinase otk 0.0035 0.0003 0.0003
Schistosoma mansoni nephrin 0.0038 0.0021 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0115 0.0574 0.4321
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0152 0.1138
Echinococcus multilocularis protein patched 0.0051 0.0117 0.0192
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0144 0.0787 0.1075
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0596 0.4025 0.4025
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0414 0.2717 0.2717
Loa Loa (eye worm) hypothetical protein 0.0079 0.0318 0.0318
Echinococcus multilocularis transfer RNA-Thr 0.0035 0.0002 0.0001
Trichomonas vaginalis STE family protein kinase 0.0092 0.0414 0.3113
Giardia lamblia Kinase, STE STE20 0.0075 0.0291 0.2186
Echinococcus granulosus tyrosine protein kinase shark 0.0064 0.0209 0.0284
Echinococcus multilocularis serine:threonine protein kinase 0.0064 0.0208 0.0342
Echinococcus multilocularis PAK box P21 Rho binding 0.0049 0.01 0.0164
Echinococcus granulosus retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Echinococcus granulosus nervana 2 0.0072 0.0268 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0044 0.0065 0.0483
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0605 0.4555
Echinococcus granulosus neuroglian 0.0093 0.042 0.0573
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0969 0.1325
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0119 0.0603 0.0603
Loa Loa (eye worm) hypothetical protein 0.0035 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0035 0.0002 0.0001
Entamoeba histolytica protein kinase, putative 0.0196 0.1152 0.8689
Echinococcus multilocularis nervana 2 0.0072 0.0268 0.0443
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0605 0.4555
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0065 0.0216 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Schistosoma mansoni hypothetical protein 0.0049 0.01 0.0233
Schistosoma mansoni tyrosine kinase 0.0082 0.0338 0.0793
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0169 0.0966 0.1599
Loa Loa (eye worm) CAMK protein kinase 0.004 0.0041 0.0041
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0092 0.0414 0.0684
Schistosoma mansoni tyrosine kinase 0.0084 0.035 0.0821
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0154 0.0856 0.6451
Schistosoma mansoni roundabout 0.0035 0.0003 0.0004
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0144 0.0787 0.1302
Schistosoma mansoni protein kinase 0.007 0.0251 0.0588
Giardia lamblia Kinase, CMGC CK2 0.0092 0.0407 0.3063
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus granulosus retinal guanylyl cyclase 2 0.0035 0.0002 0.0001
Echinococcus granulosus NCK adaptor protein 0.0047 0.0088 0.0119
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Echinococcus multilocularis casein kinase I delta 0.0061 0.0187 0.0308
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0044 0.0065 0.0065
Schistosoma mansoni serine/threonine kinase 0.0053 0.0132 0.0309
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0109 0.0535 0.0534
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0196 0.1152 0.1909
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.1642 0.3861
Echinococcus granulosus cyclin dependent kinase 5 0.0154 0.0856 0.117
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0243 0.1492 0.2472
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0617 0.1449
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0082 0.0338 0.0793
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0294 0.1856 0.1856
Echinococcus granulosus tyrosine protein kinase 0.0035 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0049 0.0104 0.0242
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0146 0.0797 0.1319
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0219 0.1321 0.1807
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0284 0.2134
Brugia malayi Protein kinase domain containing protein 0.0053 0.0132 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0132 0.0309
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0113 0.0559 0.0924
Echinococcus granulosus titin 0.004 0.0041 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0856 0.2012
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0064 0.0209 0.0344
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.007 0.0253 0.0593
Entamoeba histolytica protein kinase, putative 0.0115 0.0574 0.4319
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.1154 0.2715
Brugia malayi Protein kinase domain containing protein 0.0064 0.0209 0.0207
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.2415 0.2415
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0196 0.1154 0.1579
Echinococcus granulosus NDR protein kinase 0.0108 0.0522 0.0713
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0096 0.0437 0.0597
Loa Loa (eye worm) TK/ACK protein kinase 0.0035 0.0002 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0336 0.0787
Trypanosoma brucei aurora B kinase 0.0196 0.1152 0.8689
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0065 0.0152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0003 0.0002
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0045 0.0072 0.0533
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0264 0.1642 0.272
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0113 0.0559 0.0924
Onchocerca volvulus 0.0078 0.031 0.0891
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0061 0.0187 0.0255
Onchocerca volvulus 0.0064 0.0209 0.0597
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0047 0.0088 0.0088
Schistosoma mansoni protein kinase 0.0035 0.0002 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.1087 0.2556
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0463
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0196 0.1154 0.1154
Plasmodium vivax tyrosine kinase-like protein, putative 0.0035 0.0002 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Brugia malayi Protein kinase domain containing protein 0.0064 0.0209 0.0207
Echinococcus granulosus Glutaredoxin protein 5 0.0072 0.0268 0.0366
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0072 0.0267 0.0441
Loa Loa (eye worm) protein kinase domain-containing protein 0.0035 0.0002 0.0002
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0146 0.0797 0.0797
Brugia malayi Protein kinase domain containing protein 0.0349 0.2251 0.225
Schistosoma mansoni hypothetical protein 0.0049 0.0104 0.0242
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0222 0.1341 0.2221
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0256 0.1586 0.1586
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0113 0.0559 0.0763
Schistosoma mansoni hypothetical protein 0.0049 0.01 0.0233
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0107 0.0516 0.0516
Giardia lamblia Kinase, CDC7 0.0078 0.031 0.2331
Echinococcus granulosus CDC7 cell division cycle 7 0.0078 0.031 0.0423
Brugia malayi serine/threonine-protein kinase plk-2 0.022 0.1326 0.1325
Schistosoma mansoni ste20-related kinase 0.0202 0.1197 0.2815
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase csk 0.0035 0.0002 0.0001
Echinococcus granulosus contactin 0.0038 0.0021 0.0027
Trypanosoma cruzi casein kinase, putative 0.0061 0.0187 0.14
Echinococcus granulosus nervana 2 0.0072 0.0268 0.0366
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0153 0.0851 0.0851
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0095 0.0429 0.0709
Echinococcus multilocularis dual specificity 0.0115 0.0574 0.0949
Brugia malayi serine/threonine kinase 12 0.0196 0.1152 0.1151
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0349 0.2251 0.6493
Brugia malayi Protein kinase domain containing protein 0.0115 0.0574 0.0573
Echinococcus granulosus tyrosine kinase 0.0064 0.0209 0.0284
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni ephrin receptor 0.0102 0.0483 0.1134
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0243 0.1492 0.2472
Loa Loa (eye worm) SRC-1 0.0113 0.0559 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0336 0.0787
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0491 0.1153
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0056 0.0152 0.1314
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0082 0.0336 0.2525
Echinococcus multilocularis protein KINase family member (kin 25) 0.0035 0.0002 0.0001
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Giardia lamblia Kinase, CMGC GSK 0.0169 0.0966 0.7279
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0074 0.0284 0.2134
Echinococcus multilocularis integrin linked protein kinase 0.0035 0.0002 0.0001
Giardia lamblia Kinase, NEK 0.0129 0.0678 0.5109
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0035 0.0002 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.022 0.1326 1
Loa Loa (eye worm) TK/EPH protein kinase 0.012 0.0615 0.0615
Echinococcus granulosus cyclin dependent kinase 0.0154 0.0856 0.117
Entamoeba histolytica PH domain containing protein kinase, putative 0.0109 0.0532 0.4006
Entamoeba histolytica protein kinase, putative 0.0185 0.108 0.8142
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0072 0.0167
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0349 0.2251 0.3081
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.022 0.1326 0.2197
Echinococcus granulosus serine:threonine kinase SAD 1 0.0045 0.0072 0.0097
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0129 0.0678 0.5881
Loa Loa (eye worm) hypothetical protein 0.0146 0.0795 0.0795
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0108 0.0522 0.0864
Brugia malayi Protein kinase c protein 2 0.01 0.0467 0.0466
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0438 0.2886 0.2886
Onchocerca volvulus 0.0064 0.0209 0.0597
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0267 0.2005
Echinococcus multilocularis tyrosine kinase 0.0035 0.0002 0.0001
Trypanosoma brucei protein kinase, putative 0.0169 0.0966 0.728
Brugia malayi casein kinase I 0.0061 0.0187 0.0186
Onchocerca volvulus 0.0037 0.0014 0.0036
Plasmodium falciparum protein kinase, putative 0.0035 0.0002 0.0004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0243 0.1492 0.2041
Toxoplasma gondii STE kinase 0.0035 0.0002 0.0004
Echinococcus multilocularis dual specificity protein kinase clk2 0.0082 0.0336 0.0555
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.0812
Trypanosoma cruzi casein kinase, putative 0.0061 0.0187 0.14
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0035 0.0003 0.0003
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0099 0.046 0.3464
Brugia malayi protein unc-22 0.004 0.0041 0.004
Plasmodium falciparum NIMA related kinase 1 0.0129 0.0678 0.5881
Schistosoma mansoni rac gtpase activating protein 0.0036 0.0009 0.0019
Trichomonas vaginalis STE family protein kinase 0.0092 0.0414 0.3113
Plasmodium falciparum casein kinase 1 0.0061 0.0187 0.1615
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0076 0.03 0.0702
Brugia malayi RhoGAP domain containing protein 0.0036 0.0009 0.0008
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0093 0.0419 0.363
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0522 0.1226
Echinococcus granulosus protein kinase c iota type 0.023 0.1403 0.1919
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0076 0.03 0.0495
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0037 0.0014 0.0018
Entamoeba histolytica protein kinase, putative 0.007 0.0251 0.1882
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0061 0.0187 0.0187
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.018 0.1039 0.1039
Schistosoma mansoni protein kinase 0.0092 0.0407 0.0956
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0457 0.3028 0.3027
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Loa Loa (eye worm) hypothetical protein 0.0071 0.0263 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0021 0.002
Brugia malayi RhoGAP domain containing protein 0.0065 0.0216 0.0215
Onchocerca volvulus 0.0127 0.0664 0.1912
Echinococcus granulosus RNA directed DNA polymerase 0.0042 0.005 0.0067
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0409 0.2685 0.3674
Echinococcus multilocularis neuroglian 0.0093 0.042 0.0694
Entamoeba histolytica diacylglycerol kinase, putative 0.0036 0.0009 0.0056
Schistosoma mansoni atypical protein kinase C 0.0237 0.1448 0.3407
Schistosoma mansoni tyrosine kinase 0.0243 0.1492 0.351
Toxoplasma gondii aurora kinase 0.0196 0.1152 1
Trypanosoma cruzi casein kinase II, putative 0.0092 0.0407 0.3063
Loa Loa (eye worm) TK/FER protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0267 0.0626
Brugia malayi Protein kinase domain containing protein 0.0058 0.0165 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Loa Loa (eye worm) hypothetical protein 0.0097 0.0446 0.0446
Entamoeba histolytica tyrosin kinase, putative 0.0038 0.0025 0.0181
Echinococcus granulosus Vam6:Vps39 protein 0.0037 0.0014 0.0018
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0064 0.0208 0.0208
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.067
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0103 0.0491 0.4254
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0349 0.2251 0.225
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0277 0.0649
Brugia malayi Protein kinase domain containing protein 0.0438 0.2886 0.2886
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0789 0.1854
Schistosoma mansoni serine/threonine RGC 0.0035 0.0002 0.0001
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0603 0.0998
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Trypanosoma cruzi cdc2-related kinase 1 0.0154 0.0856 0.6451
Echinococcus granulosus defective proboscis extension response 0.0076 0.03 0.0409
Trypanosoma brucei casein kinase I, isoform 2 0.0061 0.0187 0.1403
Echinococcus granulosus tyrosine protein kinase pr2 0.0035 0.0002 0.0001
Brugia malayi Protein kinase domain containing protein 0.0072 0.0267 0.0266
Loa Loa (eye worm) serine/threonine protein kinase 0.0035 0.0002 0.0002
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0349 0.2251 0.2251
Toxoplasma gondii protein kinase domain-containing protein 0.0035 0.0002 0.0004
Onchocerca volvulus 0.0146 0.0795 0.229
Brugia malayi Protein kinase domain containing protein 0.0182 0.1054 0.1053
Brugia malayi hypothetical protein 0.0079 0.0318 0.0317
Trypanosoma cruzi cdc2-related kinase 3 0.0154 0.0856 0.6451
Entamoeba histolytica protein kinase 2, putative 0.0093 0.0419 0.3151
Echinococcus multilocularis roundabout 2 0.0038 0.0021 0.0033
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0036 0.0009 0.0009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0074 0.0284 0.0469
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0154 0.0856 0.0856
Echinococcus granulosus serine threonine protein kinase nrc 0.0093 0.0419 0.0572
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0856 0.6451
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0036 0.0009 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0196 0.1152 0.8689
Echinococcus multilocularis epidermal growth factor receptor 0.0409 0.2685 0.4449
Schistosoma mansoni tyrosine kinase 0.0409 0.2685 0.6316
Entamoeba histolytica protein kinase, putative 0.0061 0.0187 0.1402
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0063 0.0145
Plasmodium falciparum casein kinase 2, alpha subunit 0.0092 0.0407 0.3528
Toxoplasma gondii histone kinase SNF1, putative 0.0045 0.0072 0.0617
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0522 0.3929
Schistosoma mansoni protein kinase 0.0081 0.0334 0.0783
Echinococcus multilocularis aurora kinase A 0.0196 0.1152 0.1909
Echinococcus granulosus serine:threonine protein kinase 0.0064 0.0208 0.0283
Echinococcus multilocularis Immunoglobulin 0.0076 0.03 0.0495
Echinococcus granulosus mitogen activated protein kinase 11 0.0153 0.0851 0.1164
Brugia malayi Immunoglobulin I-set domain containing protein 0.026 0.1613 0.1612
Schistosoma mansoni patched 1 0.0051 0.0117 0.0273
Loa Loa (eye worm) hypothetical protein 0.0076 0.03 0.03
Echinococcus granulosus titin 0.004 0.0041 0.0055
Brugia malayi Prion-like- 0.0035 0.0003 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0185 0.108 0.8142
Brugia malayi p70 ribosomal S6 kinase beta 0.018 0.1039 0.1038
Giardia lamblia Kinase, CMGC CLK 0.0082 0.0336 0.2522
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0072 0.0267 0.0364
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0044 0.0065 0.0065
Echinococcus granulosus c src tyrosine kinase 0.0082 0.0338 0.0461
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0349 0.2251 0.373
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0075 0.0291 0.2186
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0186 0.1087 0.18
Trichomonas vaginalis CK1 family protein kinase 0.0061 0.0187 0.14
Echinococcus granulosus natriuretic peptide receptor 1 0.0035 0.0002 0.0001
Schistosoma mansoni serine/threonine-protein kinase 0.0099 0.046 0.1081
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0009 0.0008
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0049 0.01 0.0136
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0197 0.1164 0.1164
Echinococcus granulosus protein kinase shaggy 0.0169 0.0966 0.132
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0021 0.002
Echinococcus granulosus casein kinase I delta 0.0061 0.0187 0.0255
Brugia malayi Temporarily assigned gene name protein 59 0.0135 0.0722 0.0721
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0143 0.0773 0.0773
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0049 0.01 0.0233
Loa Loa (eye worm) TK protein kinase 0.0035 0.0002 0.0002
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0103 0.0491 0.3694
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.1121 0.2635
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0082 0.034 0.0464
Entamoeba histolytica hypothetical protein 0.0036 0.0009 0.0056
Schistosoma mansoni ephrin receptor 0.0037 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Brugia malayi Fibronectin type III domain containing protein 0.0079 0.0318 0.0317
Schistosoma mansoni protein kinase 0.0049 0.01 0.0233
Plasmodium falciparum protein kinase, putative 0.0056 0.0152 0.1314
Brugia malayi Protein kinase domain containing protein 0.0078 0.031 0.0309
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.067
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0115 0.0574 0.4319
Echinococcus multilocularis mitogen activated protein kinase 14 0.0153 0.0851 0.1409
Schistosoma mansoni tyrosine kinase 0.0375 0.2435 0.5728
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0154 0.0856 0.117
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0267 0.2005
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0037 0.0014 0.0095
Echinococcus multilocularis mitogen activated protein kinase 11 0.0153 0.0851 0.1409
Trichomonas vaginalis STE family protein kinase 0.0129 0.0678 0.5109
Loa Loa (eye worm) hypothetical protein 0.0076 0.03 0.03
Brugia malayi P21-Rho-binding domain containing protein 0.0049 0.01 0.0099
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.031 0.0728
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0002 0.0002
Brugia malayi diacylglycerol kinase 0.0036 0.0009 0.0008
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0103 0.0491 0.4254
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0103 0.0491 0.0812
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0035 0.0002 0.0002
Leishmania major protein kinase, putative 0.0075 0.0291 0.2186
Brugia malayi Protein kinase domain containing protein 0.0064 0.0209 0.0207
Echinococcus granulosus hemicentin 1 0.0035 0.0003 0.0003
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0035 0.0002 0.0001
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0082 0.0336 0.2525
Echinococcus granulosus protein tyrosine kinase 0.0035 0.0002 0.0001
Brugia malayi WH1 domain containing protein 0.0049 0.01 0.0099
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0074 0.0284 0.0284
Entamoeba histolytica hypothetical protein 0.0035 0.0003 0.0012
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0045 0.0072 0.0072
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0035 0.0002 0.0004
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0045 0.0072 0.0533
Schistosoma mansoni protein kinase 0.0092 0.0414 0.0972
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0209 0.0209
Entamoeba histolytica protein kinase, putative 0.0072 0.0267 0.2005
Echinococcus multilocularis 0.006 0.0185 0.0305
Loa Loa (eye worm) TK/ROR protein kinase 0.0052 0.0122 0.0122
Echinococcus multilocularis serine threonine protein kinase 0.015 0.083 0.1374
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0058 0.0165 0.0272
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0072 0.0268 0.0443
Trichomonas vaginalis CK1 family protein kinase 0.0061 0.0187 0.14
Echinococcus multilocularis kinase suppressor of Ras 1 0.0035 0.0002 0.0001
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0103 0.0491 0.3694
Trichomonas vaginalis AGC family protein kinase 0.0129 0.0678 0.5109
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0463
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0169 0.0966 0.8378
Brugia malayi hypothetical protein 0.0043 0.0063 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.3063
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0113 0.0559 0.0924
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0045 0.0072 0.0533
Entamoeba histolytica protein kinase domain containing protein 0.0191 0.1121 0.8449
Plasmodium falciparum protein kinase, putative 0.0035 0.0002 0.0004
Echinococcus multilocularis rho associated protein kinase 0.0474 0.3148 0.5217
Echinococcus multilocularis roundabout 2 0.0038 0.0021 0.0033
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0065 0.0216 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.1087 0.2556
Schistosoma mansoni adapter molecule crk 0.0047 0.0088 0.0205
Onchocerca volvulus 0.0453 0.2997 0.8646
Brugia malayi hypothetical protein 0.0064 0.0209 0.0207
Entamoeba histolytica protein kinase, putative 0.005 0.0109 0.0814
Schistosoma mansoni titin 0.004 0.0041 0.0094
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0002 0.0002
Echinococcus granulosus Immunoglobulin 0.0076 0.03 0.0409
Brugia malayi SH2 domain containing protein 0.0064 0.0209 0.0207
Loa Loa (eye worm) hypothetical protein 0.0064 0.0209 0.0209
Schistosoma mansoni serine/threonine kinase 0.0108 0.0522 0.1226
Giardia lamblia Kinase, STE STE20 0.0092 0.0414 0.3113
Entamoeba histolytica serine/threonine protein kinase, putative 0.0045 0.0072 0.0533
Giardia lamblia Kinase, CAMK CAMKL 0.0045 0.0072 0.0533
Brugia malayi Tyrosine-protein kinase abl-1 0.0082 0.0338 0.0337
Echinococcus granulosus casein kinase I alpha 0.0061 0.0187 0.0255
Echinococcus granulosus serine:threonine protein kinase 0.0064 0.0208 0.0283
Schistosoma mansoni nck2/grb4 0.0047 0.0088 0.0205
Entamoeba histolytica protein kinase, putative 0.0108 0.0522 0.3929
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0074 0.0284 0.2459
Echinococcus granulosus mitogen activated protein kinase 3 0.0074 0.0284 0.0388
Schistosoma mansoni septate junction protein 0.0035 0.0003 0.0004
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.04 0.2618 0.4339
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Entamoeba histolytica PH domain containing protein kinase, putative 0.0099 0.046 0.3464
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0061 0.0187 0.0308
Echinococcus granulosus tyrosine protein kinase csk 0.0035 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0035 0.0002 0.0001
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0146 0.0797 0.1089
Schistosoma mansoni cell adhesion molecule 0.0038 0.0021 0.0047
Brugia malayi SRC-1 0.0113 0.0559 0.0557
Loa Loa (eye worm) AGC/AKT protein kinase 0.0185 0.108 0.108
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0277 0.0457
Echinococcus multilocularis cyclin dependent kinase 5 0.0154 0.0856 0.1417
Echinococcus multilocularis casein kinase I alpha 0.0061 0.0187 0.0308
Echinococcus multilocularis unc 13 (munc13) 0.0037 0.0018 0.0029
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0053 0.0132 0.0132
Schistosoma mansoni diacylglycerol kinase theta 0.0036 0.0009 0.0019
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0035 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0127 0.0664 0.0664
Trichomonas vaginalis CK1 family protein kinase 0.0061 0.0187 0.14
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0035 0.0002 0.0001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.006 0.0179 0.0295
Onchocerca volvulus 0.004 0.0041 0.0114
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0072 0.0267 0.0267
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0082 0.0336 0.2522
Echinococcus multilocularis cyclin dependent kinase 1 0.0154 0.0856 0.1417
Brugia malayi Sex muscle abnormal protein 5 0.0047 0.0088 0.0087
Entamoeba histolytica protein kinase , putative 0.0196 0.1152 0.8689
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0072 0.0533
Echinococcus granulosus tyrosine protein kinase ABL1 0.0064 0.0209 0.0284
Brugia malayi SH2 domain containing protein 0.0064 0.0209 0.0207
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0093 0.0419 0.363
Echinococcus granulosus N chimaerin 0.0065 0.0216 0.0294
Echinococcus granulosus Rac GTPase activating protein 1 0.0036 0.0009 0.0011
Loa Loa (eye worm) TK protein kinase 0.0095 0.0429 0.0429
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0075 0.0291 0.2186
Leishmania major protein kinase, putative 0.0196 0.1152 0.8689
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0095 0.0429 0.0586
Echinococcus granulosus Diacylglycerol kinase theta 0.0036 0.0009 0.0011
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0129 0.0678 0.5881
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0064 0.0209 0.0344
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0035 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0628 0.425 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0047 0.0088 0.0144
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0277 0.5
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0035 0.0002 0.0002
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0044 0.0065 0.0483

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.0323 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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