Detailed information for compound 1387570

Basic information

Technical information
  • TDR Targets ID: 1387570
  • Name: propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-( 9H-xanthene-9-carbonylamino)thiophene-3-carbo xylate
  • MW: 506.613 | Formula: C28H30N2O5S
  • H donors: 1 H acceptors: 3 LogP: 6.1 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCN(C(=O)c1sc(c(c1C)C(=O)OC(C)C)NC(=O)C1c2ccccc2Oc2c1cccc2)CC
  • InChi: 1S/C28H30N2O5S/c1-6-30(7-2)27(32)24-17(5)22(28(33)34-16(3)4)26(36-24)29-25(31)23-18-12-8-10-14-20(18)35-21-15-11-9-13-19(21)23/h8-16,23H,6-7H2,1-5H3,(H,29,31)
  • InChiKey: HGLNLQQZOCAPIE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • isopropyl 5-(diethylcarbamoyl)-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate
  • 5-(diethylamino-oxomethyl)-4-methyl-2-[[oxo-(9H-xanthen-9-yl)methyl]amino]-3-thiophenecarboxylic acid isopropyl ester
  • 5-(diethylcarbamoyl)-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylic acid isopropyl ester
  • propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-(9H-xanthen-9-ylcarbonylamino)thiophene-3-carboxylate
  • NCGC00101217-01
  • IVK/8186349

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0094 0.1421
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0002 0.0008
Echinococcus multilocularis smad 0.001 0.001 0.001
Brugia malayi TAZ zinc finger family protein 0.0007 0.0003 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0334 0.2333
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Brugia malayi MH2 domain containing protein 0.001 0.001 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Plasmodium vivax acyl-CoA synthetase, putative 0.0089 0.0201 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0006 0.0002 0.0002
Onchocerca volvulus 0.0036 0.0074 0.1199
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0078 0.1604
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0065 0.0446
Echinococcus granulosus Smad4 0.001 0.001 0.005
Onchocerca volvulus 0.0098 0.0222 0.3678
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0078 0.1266
Echinococcus granulosus expressed conserved protein 0.0563 0.1345 0.655
Toxoplasma gondii bromodomain-containing protein 0.0007 0.0003 0.0000000046332
Brugia malayi MH1 domain containing protein 0.001 0.001 0.0071
Entamoeba histolytica hypothetical protein 0.0145 0.0336 0.233
Echinococcus granulosus smad 0.001 0.001 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0446 0.6842
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi hypothetical protein 0.0036 0.0074 0.0518
Onchocerca volvulus 0.0038 0.0078 0.1256
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0866 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0012 0.0084
Echinococcus multilocularis RUN 0.0021 0.0036 0.0036
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.0652 0.4548
Mycobacterium leprae Probable lipase LipE 0.0038 0.0078 0.2664
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Schistosoma mansoni DNA ligase IV 0.004 0.0082 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0078 0.0865
Onchocerca volvulus Serine\/threonine kinase homolog 0.0116 0.0265 0.4409
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0012 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0078 0.1166
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0108 0.0526
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Onchocerca volvulus 0.0038 0.0078 0.1256
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0036 0.0177
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0012 0.0059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0012 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.0423 0.7058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0012 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0065 0.0446
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0074 0.0165 0.1154
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0035 0.0071 0.2409
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.004 0.0082 0.0919
Loa Loa (eye worm) hypothetical protein 0.0052 0.0112 0.0782
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0035 0.0071 0.2409
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.001 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0078 0.0865
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Brugia malayi ecdysteroid receptor 0.0011 0.0012 0.0084
Echinococcus multilocularis tumor protein p63 0.07 0.1676 0.1676
Brugia malayi Smad1 0.001 0.001 0.0071
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Schistosoma mansoni smad 0.001 0.001 0.007
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0035 0.0071 0.1145
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0003 0.0016
Entamoeba histolytica hypothetical protein 0.004 0.0082 0.0555
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0015 0.0103
Brugia malayi Patched related family protein 12 0.0036 0.0074 0.0518
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0154 0.0358 0.0358
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.0568 1
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0012 0.0084
Brugia malayi Bromodomain containing protein 0.0085 0.019 0.1329
Loa Loa (eye worm) beta-lactamase 0.0038 0.0078 0.0541
Echinococcus granulosus nibrin 0.004 0.0082 0.04
Echinococcus multilocularis peregrin 0.0007 0.0003 0.0003
Onchocerca volvulus Huntingtin homolog 0.0148 0.0343 0.5722
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.004 0.0082 0.0555
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0012 0.0155
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0287 0.0678 0.7818
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0119 0.0273 0.6022
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0019
Echinococcus granulosus replication factor c subunit 1 0.004 0.0082 0.04
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0071 0.0787
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0094 0.0458
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Schistosoma mansoni lipoxygenase 0.0086 0.0195 0.134
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0035 0.0071 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0089 0.0201 0.3462
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0024 0.0024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0035 0.0071 0.0345
Echinococcus multilocularis polybromo 1 0.0007 0.0003 0.0003
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0166 0.1155
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0012 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.0866 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0119 0.0273 0.1893
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Entamoeba histolytica protein kinase, putative 0.0287 0.0678 0.4721
Leishmania major hypothetical protein, conserved 0.0038 0.0078 0.0865
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0117 0.1768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0084 0.0189 0.3253
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0119 0.0273 0.1893
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0006 0.0042
Echinococcus multilocularis c src tyrosine kinase 0.0006 0.0002 0.0002
Echinococcus granulosus bromodomain containing 2 0.0007 0.0003 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus bromodomain containing protein 8 0.0007 0.0003 0.0014
Loa Loa (eye worm) SRC-1 0.0006 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Brugia malayi polybromodomain protein 0.0007 0.0003 0.002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0012 0.0059
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0012 0.0083
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0024 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0012 0.0084
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0006 0.0002 0.0002
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0007 0.0003 0.0014
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0138 0.0962
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0012 0.0084
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0334 0.2333
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0089 0.0201 0.4386
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0112 0.0546
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Echinococcus multilocularis nibrin 0.004 0.0082 0.0082
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0035 0.0071 0.1451
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0078 0.0865
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi SRC-1 0.0006 0.0002 0.0012
Loa Loa (eye worm) patched family protein 0.0036 0.0074 0.0518
Brugia malayi acetyltransferase, GNAT family protein 0.0178 0.0415 0.2894
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0012 0.0084
Echinococcus multilocularis dual specificity 0.0287 0.0678 0.0678
Entamoeba histolytica ankyrin repeat protein, putative 0.0007 0.0003 0.000000022518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0012 0.0061
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.0579 0.4042
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.004 0.0082 0.0919
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0257 0.0607 0.4238
Schistosoma mansoni polybromo-1 0.0007 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Echinococcus multilocularis global transcription activator snf2l2 0.0007 0.0003 0.0003
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0024 0.0244
Schistosoma mansoni ferritin light chain 0.0008 0.0006 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus granulosus neuropeptide s receptor 0.056 0.1338 0.6514
Loa Loa (eye worm) hypothetical protein 0.0063 0.014 0.0974
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0124 0.0285 0.1387
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.0947 0.0947
Brugia malayi Ets-domain containing protein 0.0074 0.0166 0.1155
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0087
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Echinococcus granulosus tyrosine protein kinase Src42A 0.0006 0.0002 0.0008
Loa Loa (eye worm) patched family protein 0.0036 0.0074 0.0518
Mycobacterium ulcerans acyl-CoA synthetase 0.0119 0.0273 0.6022
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.011 0.1244
Schistosoma mansoni ets 0.0011 0.0012 0.0086
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Echinococcus granulosus tumor protein p63 0.07 0.1676 0.8163
Schistosoma mansoni zinc finger protein 0.0026 0.005 0.0345
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0678 0.4721
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0012 0.0012
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0094 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0209 0.1461
Entamoeba histolytica hypothetical protein 0.0145 0.0336 0.233
Echinococcus granulosus survival motor neuron protein 1 0.0478 0.114 0.5551
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0209 0.0209
Echinococcus granulosus Protein patched homolog 1 0.0257 0.0607 0.2957
Brugia malayi protein C24B5.3 0.0036 0.0074 0.0518
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.0084 0.0583
Echinococcus granulosus Bromodomain containing protein 0.0007 0.0003 0.0014
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0071 0.1061
Brugia malayi nuclear hormone receptor 0.0011 0.0012 0.0084
Schistosoma mansoni chromosome transmission fidelity factor 0.004 0.0082 0.0564
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0024 0.0311
Plasmodium falciparum lipid/sterol:H+ symporter 0.0036 0.0074 0.3603
Schistosoma mansoni apoferritin-2 0.0008 0.0006 0.0044
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Echinococcus granulosus GPCR family 2 0.0052 0.0112 0.0546
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis ferritin, putative 0.0008 0.0006 0.0071
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0071 0.0787
Giardia lamblia Kinase, PLK 0.0116 0.0265 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0094 0.0638
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0287 0.0678 0.7818
Brugia malayi Pre-SET motif family protein 0.0032 0.0065 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0082 0.1237
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.007
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0035 0.0071 0.0071
Loa Loa (eye worm) Smad1 0.001 0.001 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Echinococcus multilocularis expressed conserved protein 0.0563 0.1345 0.1345
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0012 0.0012
Loa Loa (eye worm) acetyltransferase 0.0178 0.0415 0.2894
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0152 0.0739
Brugia malayi follicle stimulating hormone receptor 0.0246 0.0579 0.4042
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0138 0.0962
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Brugia malayi Pax transcription activation domain interacting protein 0.004 0.0082 0.0573
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.004 0.0082 0.1237
Schistosoma mansoni ferritin 0.0008 0.0006 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0012 0.0084
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0117 0.0568
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0012 0.0083
Toxoplasma gondii patched family protein 0.0036 0.0074 0.0103
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0078 0.1266
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0012 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0119 0.0273 0.3134
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0012 0.0083
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0071 0.1145
Trichomonas vaginalis lymphoid specific helicase, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0024 0.0024
Schistosoma mansoni Smad4 0.001 0.001 0.007
Loa Loa (eye worm) fli-1 protein 0.0225 0.053 0.3698
Schistosoma mansoni transcription initiation factor tfiid 0.0007 0.0003 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi ATPase, AAA family protein 0.0007 0.0003 0.002
Schistosoma mansoni ferritin light chain 0.0008 0.0006 0.0044
Onchocerca volvulus 0.0035 0.0071 0.1141
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0116 0.0265 0.1851
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0003 0.0016
Echinococcus granulosus neuropeptide receptor A26 0.056 0.1338 0.6514
Schistosoma mansoni bromodomain containing protein 0.001 0.0012 0.0079
Toxoplasma gondii propionate-CoA ligase 0.0035 0.0071 0.0098
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0078 0.0533
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0119 0.0273 0.4753
Echinococcus multilocularis protein patched 0.0257 0.0607 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Schistosoma mansoni bromodomain containing protein 0.0072 0.0161 0.1105
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0287 0.0678 0.7818
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0042 0.0089 0.4351
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0002 0.0002
Brugia malayi Niemann-Pick C1 protein precursor 0.06 0.1433 1
Brugia malayi protein C24B5.3 0.0036 0.0074 0.0518
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0035 0.0071 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Loa Loa (eye worm) hypothetical protein 0.005 0.0108 0.0754
Echinococcus multilocularis sterol regulatory element binding protein 0.0257 0.0607 0.0607
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0403 0.4633
Schistosoma mansoni hypothetical protein 0.0112 0.0258 0.1771
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) oxidoreductase 0.0035 0.0071 0.0494
Brugia malayi Ets-domain containing protein 0.0074 0.0166 0.1155
Schistosoma mansoni tyrosine kinase 0.0151 0.0352 0.2418
Toxoplasma gondii hypothetical protein 0.0059 0.0128 0.0181
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.001 0.001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0112 0.0782
Schistosoma mansoni zinc finger protein 0.0016 0.0025 0.0173
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Echinococcus granulosus dnaJ subfamily B 0.0398 0.0947 0.4612
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0607 0.9317
Echinococcus granulosus expressed protein 0.0008 0.0006 0.0031
Entamoeba histolytica serine/threonine protein kinase, putative 0.0116 0.0265 0.1835
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0024 0.0167
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0035 0.0071 0.1145
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0222 0.1548
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.003 0.003
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0012 0.0084
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0035 0.0071 0.1145
Echinococcus multilocularis replication factor c subunit 1 0.004 0.0082 0.0082
Entamoeba histolytica acyl-coA synthetase, putative 0.0119 0.0273 0.1893
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.0383 0.2675
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0094 0.0131
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis cpg binding protein 0.0032 0.0063 0.0063
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni patched 1 0.0257 0.0607 0.4172
Echinococcus multilocularis Niemann Pick C1 protein 0.06 0.1433 0.1433
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0071 0.1451
Toxoplasma gondii ABC1 family protein 0.0038 0.0078 0.0108
Schistosoma mansoni hypothetical protein 0.0052 0.0112 0.077
Brugia malayi nuclear receptor NHR-88 0.0011 0.0012 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0119 0.0273 0.1909
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.004 0.0082 0.2836
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus multilocularis neuropeptide receptor A26 0.056 0.1338 0.1338
Schistosoma mansoni gabp alpha 0.0074 0.0166 0.1137
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0133 0.0188
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0006 0.003
Onchocerca volvulus 0.0036 0.0074 0.1199
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0209 0.1439
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0446 0.6842
Schistosoma mansoni ets-related 0.0225 0.053 0.3641
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0006 0.0006
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0012 0.0061
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0012 0.0084
Schistosoma mansoni cpg binding protein 0.0032 0.0063 0.043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0012 0.0084
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.0059 0.0937
Echinococcus granulosus zinc finger protein 0.0026 0.005 0.0244
Loa Loa (eye worm) RNA binding protein 0.0063 0.0138 0.0962
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0397 0.1933
Schistosoma mansoni topbp1 0.004 0.0082 0.0564
Schistosoma mansoni hypothetical protein 0.0022 0.0039 0.0266
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Echinococcus granulosus sterol regulatory element binding protein 0.0257 0.0607 0.2957
Echinococcus granulosus tyrosine protein kinase Src64B 0.0006 0.0002 0.0008
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Loa Loa (eye worm) patched family protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) hypothetical protein 0.0148 0.0343 0.2397
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Echinococcus multilocularis tyrosine protein kinase Abl 0.0006 0.0002 0.0002
Trichomonas vaginalis hypothetical protein 0.0007 0.0003 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0209 0.1439
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis protein dispatched 1 0.0294 0.0695 0.0695
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0082 0.0919
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0006 0.0002 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Plasmodium vivax acetyl-CoA synthetase, putative 0.0035 0.0071 0.3429
Echinococcus multilocularis ets variant gene 4 0.0011 0.0012 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0052 0.0112 0.077
Mycobacterium tuberculosis Conserved protein 0.0038 0.0078 0.1266
Loa Loa (eye worm) hypothetical protein 0.0164 0.0383 0.2675
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0126 0.1916
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.045 0.7893
Onchocerca volvulus 0.0036 0.0074 0.1199
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0047 0.0047
Brugia malayi MH2 domain containing protein 0.0144 0.0334 0.2333
Schistosoma mansoni hypothetical protein 0.0042 0.0089 0.0612
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0138 0.0947
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0078 0.0378
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.007
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0166 0.0806
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0094 0.1421
Brugia malayi Pre-SET motif family protein 0.0223 0.0524 0.3657
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0012 0.0061
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0006 0.0002 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0006 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0012 0.0084
Schistosoma mansoni hypothetical protein 0.0011 0.0012 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Brugia malayi Tyrosine-protein kinase abl-1 0.0006 0.0002 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0678 0.4658
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0071 0.1145
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0084 0.0189 0.3253
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.001 0.005
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0178 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Onchocerca volvulus 0.0021 0.0036 0.0563
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0078 0.1266
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0082 0.1237
Schistosoma mansoni tyrosine kinase 0.0006 0.0002 0.0012
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0035 0.0071 0.1451
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.0258 0.1799
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0012 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0071 0.1145
Brugia malayi CHE-14 protein 0.0257 0.0607 0.4238
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0012 0.0059
Schistosoma mansoni hypothetical protein 0.0021 0.0036 0.025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus multilocularis bromodomain containing 2 0.0007 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Schistosoma mansoni hypothetical protein 0.0248 0.0585 0.4019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0084 0.0189 0.3253
Mycobacterium tuberculosis Conserved protein 0.0038 0.0078 0.1266
Brugia malayi hypothetical protein 0.0145 0.0336 0.2345
Echinococcus granulosus dual specificity 0.0287 0.0678 0.3301
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0012 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0209 0.1439
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0071 0.0787
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0035 0.0071 0.2409
Brugia malayi Bromodomain containing protein 0.0044 0.0094 0.0654
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus polybromo 1 0.0007 0.0003 0.0014
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Echinococcus multilocularis protein kinase C binding protein 1 0.0007 0.0003 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0012 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0209 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Loa Loa (eye worm) CBP-B 0.0007 0.0003 0.002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.0524 0.3657
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0024 0.0244
Brugia malayi beta-lactamase 0.0038 0.0078 0.0541
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0024 0.0167
Schistosoma mansoni CREB-binding protein 2 0.0007 0.0003 0.0019
Echinococcus multilocularis 0.0007 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0035 0.0071 0.1451
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0004 0.0039
Echinococcus multilocularis Smad4 0.001 0.001 0.001
Onchocerca volvulus 0.0119 0.0273 0.4547
Mycobacterium ulcerans acyl-CoA synthetase 0.0119 0.0273 0.6022
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0094 0.1057
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0047 0.0231
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0094 0.0094
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Onchocerca volvulus 0.0038 0.0078 0.1256
Echinococcus multilocularis expressed protein 0.0008 0.0006 0.0006
Trypanosoma brucei polo-like protein kinase 0.0116 0.0265 0.3039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi Patched protein homolog 1 0.0036 0.0074 0.0518
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0119 0.0273 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0089 0.0201 1
Trypanosoma cruzi ISWI complex protein 0.0016 0.0025 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0257 0.0607 0.4238
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0035 0.0071 0.1451
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0035 0.0071 0.0494
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0082 0.0919
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0103 0.0234 0.1632
Brugia malayi serine/threonine-protein kinase plk-2 0.0116 0.0265 0.1851
Trichomonas vaginalis replication factor C large subunit, putative 0.004 0.0082 0.1237
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0071 0.0787
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0494
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Onchocerca volvulus 0.0035 0.0071 0.1141
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0209 0.0209
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Onchocerca volvulus 0.0036 0.0074 0.1199
Plasmodium falciparum acyl-CoA synthetase 0.0089 0.0201 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.0697
Schistosoma mansoni ets-related 0.0011 0.0012 0.0086
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0083 0.136
Brugia malayi MH2 domain containing protein 0.001 0.001 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0012 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.0119 0.0273 0.6022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0119 0.0273 0.4753
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0138 0.0947
Onchocerca volvulus Protein patched homolog 0.0036 0.0074 0.1199
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0423 0.648
Loa Loa (eye worm) hypothetical protein 0.06 0.1433 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0119 0.0273 0.1909
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0094 0.1057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0287 0.0678 0.4731
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0012 0.0084
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Entamoeba histolytica hypothetical protein 0.0145 0.0336 0.233
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus global transcription activator snf2l2 0.0007 0.0003 0.0014
Brugia malayi BRM protein 0.0007 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Giardia lamblia Replication factor C, subunit 1 0.004 0.0082 0.3023
Schistosoma mansoni hypothetical protein 0.0398 0.0947 0.6508
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0138 0.0947
Brugia malayi beta-lactamase family protein 0.0038 0.0078 0.0541
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0119 0.0273 0.1909
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0035 0.0071 0.1451
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0078 0.3772
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0004 0.0039
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0177
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0078 0.2664
Echinococcus granulosus cpg binding protein 0.0032 0.0063 0.0305
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0078 0.0541
Onchocerca volvulus 0.004 0.0082 0.1333
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Schistosoma mansoni bromodomain containing protein 0.0007 0.0003 0.0019
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0012 0.0087
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0047 0.0325
Schistosoma mansoni hypothetical protein 0.0248 0.0585 0.4019
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0035 0.0071 0.1145
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0071 0.1145
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0036 0.1693
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0024 0.0116
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0287 0.0678 0.4731
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0007 0.0003 0.0019
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0012 0.0083
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0012 0.0083
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Trypanosoma cruzi ISWI complex protein 0.0016 0.0025 0.0259
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0078 0.0078
Brugia malayi hypothetical protein 0.0036 0.0074 0.0518
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Onchocerca volvulus 0.0036 0.0074 0.1199
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0265 0.1823
Brugia malayi polybromodomain protein 0.0007 0.0003 0.002
Brugia malayi hypothetical protein 0.004 0.0082 0.0573
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.004 0.0082 0.1237
Brugia malayi CXXC zinc finger family protein 0.0028 0.0054 0.0376
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.0336 0.2309
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0003 0.0016
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0012 0.0155
Echinococcus granulosus protein C ets 2 0.0011 0.0012 0.0061
Loa Loa (eye worm) BRM protein 0.0007 0.0003 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0061 0.0295
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0007 0.0003 0.0019
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0012 0.0083
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0112 0.0782
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0094 0.1057
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.0652 0.4548
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Echinococcus multilocularis ferritin 0.0008 0.0006 0.0006
Schistosoma mansoni tyrosine kinase 0.0006 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0042 0.0089 0.0621
Brugia malayi Myosin head containing protein 0.0036 0.0074 0.0518
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0109 0.0758
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.001 0.001
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.01 0.4921
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.004 0.0082 0.1237
Brugia malayi hypothetical protein 0.0036 0.0074 0.0518
Echinococcus granulosus ferritin 0.0008 0.0006 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0084 0.0189 0.3253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0012 0.0084
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0012 0.0061
Toxoplasma gondii patched family protein 0.0036 0.0074 0.0103
Mycobacterium ulcerans lipase LipD 0.0038 0.0078 0.1604
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0112 0.0782
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0254
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0078 0.1166
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0036 0.1693
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0083 0.2861
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0012 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0082 0.1237
Echinococcus granulosus tyrosine protein kinase Lyn 0.0008 0.0006 0.003
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0036 0.0254
Schistosoma mansoni hypothetical protein 0.0052 0.0112 0.077
Brugia malayi beta-lactamase family protein 0.0038 0.0078 0.0541
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0036 0.0036
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0094 0.1977
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0254
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0078 0.0533
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0012 0.0087
Loa Loa (eye worm) histone methyltransferase 0.001 0.001 0.0071
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Schistosoma mansoni cpg binding protein 0.0028 0.0054 0.0371
Mycobacterium tuberculosis Conserved protein 0.0038 0.0078 0.1266
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.0383 0.2675
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0006 0.0002 0.0008
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0071 0.0787
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0006 0.003
Toxoplasma gondii patched family protein 0.0036 0.0074 0.0103
Brugia malayi hypothetical protein 0.0036 0.0074 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Onchocerca volvulus 0.0036 0.0074 0.1199
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.004 0.0082 0.0114
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.004 0.0082 0.1237
Echinococcus multilocularis protein C ets 2 0.0011 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0016 0.0025 0.0173
Treponema pallidum DNA ligase (lig) 0.004 0.0082 1
Loa Loa (eye worm) hypothetical protein 0.0478 0.114 0.7956
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0071 0.0787
Schistosoma mansoni cpg binding protein 0.0032 0.0063 0.043
Echinococcus granulosus RUN 0.0021 0.0036 0.0177
Trypanosoma cruzi polo-like protein kinase, putative 0.0116 0.0265 0.3039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0006 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0089 0.0201 0.1402
Trypanosoma brucei AAA ATPase, putative 0.0007 0.0003 0.0000039754
Loa Loa (eye worm) hypothetical protein 0.0089 0.0201 0.1402
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0012 0.0084
Schistosoma mansoni polycystin 1-related 0.0021 0.0036 0.025
Schistosoma mansoni apoferritin-2 0.0008 0.0006 0.0044
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0108 0.0742
Brugia malayi Doublecortin family protein 0.0021 0.0036 0.0254
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0035 0.0071 0.0494
Onchocerca volvulus 0.0103 0.0234 0.3881
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0012 0.0083
Schistosoma mansoni kinase 0.0059 0.013 0.0893
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.001 0.005
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0012 0.0086
Plasmodium vivax SET domain protein, putative 0.0032 0.0065 0.3131
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0007 0.0003 0.0016
Onchocerca volvulus 0.0011 0.0012 0.0155
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0078 0.1166
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0012 0.0059
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0007 0.0003 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0077 0.0377
Schistosoma mansoni ferritin 0.0008 0.0006 0.0044
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0012 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0137 0.1557
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0024 0.1062
Loa Loa (eye worm) hypothetical protein 0.0089 0.0201 0.1402
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0094 0.1057
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0119 0.0273 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0024 0.0164
Schistosoma mansoni acetyl-CoA synthetase 0.0035 0.0071 0.0486
Onchocerca volvulus Protein patched homolog 0.0036 0.0074 0.1199
Echinococcus granulosus CREB binding protein 0.0007 0.0003 0.0014
Echinococcus multilocularis Bromodomain containing protein 0.0007 0.0003 0.0003
Echinococcus multilocularis Niemann Pick C1 protein 0.0857 0.2054 0.2054
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0012 0.0084
Loa Loa (eye worm) patched family protein 0.0036 0.0074 0.0518
Echinococcus granulosus PH interacting protein 0.0007 0.0003 0.0014
Echinococcus multilocularis bromodomain containing protein 8 0.0007 0.0003 0.0003
Schistosoma mansoni ferritin 0.0008 0.0006 0.0044
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.0866 1
Loa Loa (eye worm) hypothetical protein 0.0285 0.0674 0.47
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0403 0.4633
Toxoplasma gondii ATPase, AAA family protein 0.004 0.0082 0.0114
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0042 0.029
Brugia malayi hypothetical protein 0.0148 0.0343 0.2397
Mycobacterium ulcerans beta-lactamase 0.0038 0.0078 0.1604
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0006 0.0002 0.0002
Echinococcus granulosus Bromodomain containing protein 0.0007 0.0003 0.0014
Echinococcus granulosus peregrin 0.0007 0.0003 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0012 0.0084
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0178 0.0415 0.285
Schistosoma mansoni inositol monophosphatase 0.0045 0.0094 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0082 0.1237
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0071 0.1061
Onchocerca volvulus 0.0035 0.0071 0.1141
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Schistosoma mansoni ferritin 0.0008 0.0006 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0209 0.102
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0006 0.0006
Trypanosoma cruzi polo-like protein kinase, putative 0.0116 0.0265 0.3039
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0124 0.0285 0.0285
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0012 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Schistosoma mansoni coup transcription factor 0.0011 0.0012 0.0083
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.0621
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Onchocerca volvulus 0.0036 0.0074 0.1199
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0071 0.0787
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0012 0.0084
Onchocerca volvulus 0.0021 0.0036 0.0563
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0078 0.1166
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.001 0.0071
Schistosoma mansoni tyrosine kinase 0.0006 0.0002 0.0012
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0116 0.0265 0.3039
Schistosoma mansoni survival motor neuron protein 0.0098 0.0222 0.1524
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.011 0.1244
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.001 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0116 0.0265 0.0265
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0007 0.0003 0.0003
Mycobacterium ulcerans acetyl-CoA synthetase 0.0035 0.0071 0.1451
Echinococcus multilocularis survival motor neuron protein 1 0.0478 0.114 0.114
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Plasmodium vivax patched family protein, putative 0.0036 0.0074 0.3603
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) inositol-1 0.0045 0.0094 0.0657
Loa Loa (eye worm) bromodomain containing protein 0.0007 0.0003 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0126 0.1916
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni hypothetical protein 0.0098 0.0222 0.1524
Schistosoma mansoni hypothetical protein 0.0145 0.0336 0.2309
Mycobacterium ulcerans hypothetical protein 0.0038 0.0078 0.1604
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Onchocerca volvulus Huntingtin homolog 0.0148 0.0343 0.5722
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0094 0.1421
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0078 0.1604
Loa Loa (eye worm) patched family protein 0.0036 0.0074 0.0518
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0152 0.0152
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0042 0.0089 0.0621
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0035 0.0071 0.0787
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0012 0.0084
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0012 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0071 0.1451
Entamoeba histolytica hypothetical protein 0.0145 0.0336 0.233
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0042 0.0089 0.0621
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0112 0.0546
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0065 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0494
Brugia malayi MH1 domain containing protein 0.001 0.001 0.0071
Entamoeba histolytica protein kinase, putative 0.0287 0.0678 0.4721
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0035 0.0071 0.1145
Brugia malayi Inositol-1 0.0045 0.0094 0.0657
Plasmodium vivax replication factor C subunit 1, putative 0.004 0.0082 0.4004
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0117 0.1768
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis zinc finger protein 0.0026 0.005 0.005
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Plasmodium vivax SET domain containing protein 0.0009 0.0007 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0024 0.1062
Schistosoma mansoni phd finger protein 0.0007 0.0003 0.0019
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0042 0.0089 0.0089
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.0336 0.1636
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0012 0.0155
Schistosoma mansoni topbp1 0.004 0.0082 0.0564
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0119 0.0273 0.6022
Trichomonas vaginalis set domain proteins, putative 0.0253 0.0598 0.9175
Trichomonas vaginalis esterase, putative 0.0038 0.0078 0.1166
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0119 0.0273 0.1909
Schistosoma mansoni bromodomain containing 0.0007 0.0003 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0132 0.091
Echinococcus granulosus Niemann Pick C1 protein 0.06 0.1433 0.6977
Trichomonas vaginalis hypothetical protein 0.0007 0.0003 0.0016
Brugia malayi transcription factor E74 isoform 0.0011 0.0012 0.0087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0012 0.0012
Brugia malayi hypothetical protein 0.0021 0.0036 0.0254
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.06 0.1433 1
Brugia malayi Patched related family protein 10 0.0036 0.0074 0.0518
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.001 0.0071
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0035 0.0071 0.0475
Trypanosoma brucei ISWI complex protein 0.0016 0.0025 0.0259
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0116 0.0265 0.1292
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Brugia malayi DKFZp564C0469 protein 0.004 0.0082 0.0573
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.004 0.0082 0.0573
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0024 0.0244
Plasmodium falciparum replication factor C subunit 1, putative 0.004 0.0082 0.4004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0117 0.5746
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0209 0.1461
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0138 0.0138
Brugia malayi steroid hormone receptor 0.0011 0.0012 0.0084
Loa Loa (eye worm) hypothetical protein 0.0089 0.0201 0.1402
Brugia malayi topoisomerase 0.004 0.0082 0.0573
Loa Loa (eye worm) hypothetical protein 0.0112 0.0258 0.1799
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0117 0.0164
Loa Loa (eye worm) hypothetical protein 0.0038 0.0078 0.0541
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.011 0.1244
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0035 0.0071 0.1451
Schistosoma mansoni hypothetical protein 0.0248 0.0585 0.4019
Plasmodium falciparum bromodomain protein 1 0.0007 0.0003 0.00000016256
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0024 0.0244
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0006 0.0002 0.0008
Brugia malayi hypothetical protein 0.0038 0.0079 0.0552
Echinococcus multilocularis GPCR, family 2 0.0052 0.0112 0.0112
Schistosoma mansoni elf1 0.0011 0.0012 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0078 0.1166
Toxoplasma gondii patched family protein 0.0036 0.0074 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.0652 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0012 0.0084
Loa Loa (eye worm) hypothetical protein 0.0119 0.0273 0.1909
Loa Loa (eye worm) hypothetical protein 0.0315 0.0747 0.5212
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.001 0.001
Brugia malayi PHD-finger family protein 0.0032 0.0064 0.0445
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Brugia malayi isocitrate dehydrogenase 0.0015 0.0024 0.0167
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.004 0.0082 0.1708
Onchocerca volvulus 0.0028 0.0054 0.0859
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Leishmania major hypothetical protein, conserved 0.0016 0.0025 0.0259
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0609 0.1455 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0078 0.1266
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0042 0.0089 0.4351
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0078 0.0541
Mycobacterium ulcerans hypothetical protein 0.0192 0.045 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0024 0.0024
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.004 0.0082 0.8637
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0012 0.0084
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0065 0.0089
Schistosoma mansoni smad1 5 8 and 0.001 0.001 0.007
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0138 0.0947
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.01 0.3715
Onchocerca volvulus 0.0035 0.0071 0.1141
Brugia malayi hypothetical protein 0.0038 0.0079 0.0552
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Schistosoma mansoni inositol monophosphatase 0.0045 0.0094 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0078 0.1266
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0573
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0035 0.0071 0.1145
Schistosoma mansoni hypothetical protein 0.0248 0.0585 0.4019
Toxoplasma gondii hypothetical protein 0.0036 0.0074 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0078 0.1266
Schistosoma mansoni lipoxygenase 0.0124 0.0285 0.1957
Brugia malayi Bromodomain containing protein 0.0007 0.0003 0.002
Echinococcus multilocularis Bromodomain containing protein 0.0007 0.0003 0.0003
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0054 0.0376
Onchocerca volvulus 0.0253 0.0598 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0154 0.0358 0.1745
Schistosoma mansoni hypothetical protein 0.0011 0.0012 0.0086
Brugia malayi Fli-1 protein 0.0225 0.053 0.3698
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.0383 0.2675
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0024 0.0244
Loa Loa (eye worm) hypothetical protein 0.0285 0.0674 0.47
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0012 0.0087
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0108 0.0108
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0287 0.0678 0.7818
Loa Loa (eye worm) hypothetical protein 0.0089 0.0201 0.1402
Echinococcus granulosus protein kinase C binding protein 1 0.0007 0.0003 0.0014
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0012 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0012 0.0012
Brugia malayi TAR-binding protein 0.0063 0.0138 0.0962
Brugia malayi RNA binding protein 0.0063 0.0138 0.0962
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.01 0.0682
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0039 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0403 0.4633
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.0265 0.4054
Brugia malayi Patched related family protein 4 0.0036 0.0074 0.0518
Echinococcus multilocularis neuropeptide s receptor 0.056 0.1338 0.1338
Entamoeba histolytica hypothetical protein 0.0287 0.0678 0.4721
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) hypothetical protein 0.0148 0.0343 0.2397
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0071 0.0494
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0007 0.0003 0.00000016256
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.003 0.0144
Trichomonas vaginalis bromodomain containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0108 0.0742
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0077 0.0077
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0012 0.0087
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0138 0.0947
Brugia malayi Patched family protein 0.0036 0.0074 0.0518
Leishmania major 4-coumarate:coa ligase-like protein 0.0119 0.0273 0.3134
Schistosoma mansoni tyrosine kinase 0.0006 0.0002 0.0012
Echinococcus granulosus c src tyrosine kinase 0.0006 0.0002 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0012 0.0083
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0119 0.0273 0.6022
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0117 0.0164
Brugia malayi Ets-domain containing protein 0.0011 0.0012 0.0087
Onchocerca volvulus 0.0032 0.0065 0.1042
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0234 0.1607
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0518
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0012 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0012 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0003 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.003 0.0204
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus granulosus tar DNA binding protein 0.0063 0.0138 0.0671
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.2888 0.6953 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0035 0.0071 0.3429
Brugia malayi hypothetical protein 0.004 0.0082 0.0573
Echinococcus granulosus Niemann Pick C1 protein 0.0857 0.2054 1
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0042 0.0089 0.0124
Brugia malayi hypothetical protein 0.0021 0.0036 0.0254
Trypanosoma cruzi FHA domain containing protein, putative 0.004 0.0082 0.0919
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0012 0.0084
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0119 0.0273 0.6022
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.011 0.1244
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0012 0.0012
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0071 0.0787
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0078 0.1266
Schistosoma mansoni hypothetical protein 0.0052 0.0112 0.077
Brugia malayi bromodomain containing protein 0.0007 0.0003 0.002
Brugia malayi AMP-binding enzyme family protein 0.0119 0.0273 0.1909
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0002 0.0008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.003 0.0204
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0012 0.0061
Schistosoma mansoni helicase 0.0007 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Leishmania major 4-coumarate:coa ligase-like protein 0.0119 0.0273 0.3134
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0071 0.1145
Mycobacterium ulcerans hypothetical protein 0.0119 0.0273 0.6022
Schistosoma mansoni loxhd1 0.0021 0.0036 0.025
Brugia malayi hypothetical protein 0.0478 0.114 0.7956
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0012 0.0084
Echinococcus granulosus CREB binding protein 0.0007 0.0003 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis PH interacting protein 0.0007 0.0003 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0138 0.0962
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.0866 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0007 0.0003 0.0016
Echinococcus multilocularis CREB binding protein 0.0007 0.0003 0.0003
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0035 0.0071 0.1451
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0082 0.1237

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.631 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) = 5.6234 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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