Detailed information for compound 1618000

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.353 | Formula: C20H16N2O3
  • H donors: 3 H acceptors: 3 LogP: 4.11 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(c(c1O)O)/C=N/N=C(c1ccccc1)c1ccccc1
  • InChi: 1S/C20H16N2O3/c23-17-12-11-16(19(24)20(17)25)13-21-22-18(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,23-25H/b21-13+
  • InChiKey: YBAIWUIPYQTZEG-FYJGNVAPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Trypanosoma brucei hypothetical protein, conserved Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens Bloom syndrome, RecQ helicase-like Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Starlite/ChEMBL No references
Homo sapiens myeloid cell leukemia 1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Homo sapiens calcium channel, voltage-dependent, N type, alpha 1B subunit Starlite/ChEMBL No references
Homo sapiens Wolf-Hirschhorn syndrome candidate 1 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens mannose phosphate isomerase Starlite/ChEMBL No references
Homo sapiens amyloid beta (A4) precursor protein-binding, family A, member 1 No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens glutaminase Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Neospora caninum hypothetical protein Get druggable targets OG5_127555 All targets in OG5_127555
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho Get druggable targets OG5_127555 All targets in OG5_127555
Trypanosoma brucei gambiense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania donovani phosphomannose isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Echinococcus multilocularis mannose 6 phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus amyloid beta A4 protein Get druggable targets OG5_130749 All targets in OG5_130749
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni high voltage-activated calcium channel Cav1 Get druggable targets OG5_126791 All targets in OG5_126791
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania mexicana glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus multilocularis voltage dependent calcium channel type d subunit Get druggable targets OG5_126791 All targets in OG5_126791
Plasmodium knowlesi mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis voltage dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase Get druggable targets OG5_131193 All targets in OG5_131193
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Theileria parva mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K01809 mannose-6-phosphate isomerase [EC5.3.1.8], putative Get druggable targets OG5_127555 All targets in OG5_127555
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO Get druggable targets OG5_127555 All targets in OG5_127555
Trypanosoma cruzi phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Echinococcus multilocularis histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Schistosoma japonicum Voltage-dependent P/Q-type calcium channel subunit alpha-1A, putative Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma mansoni amyloid beta A4 protein related Get druggable targets OG5_130749 All targets in OG5_130749
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Voltage-dependent P/Q-type calcium channel subunit alpha-1A, putative Get druggable targets OG5_126791 All targets in OG5_126791
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis amyloid beta A4 protein Get druggable targets OG5_130749 All targets in OG5_130749
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium berghei mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04850 calcium channel, voltage-dependent, L type, alpha 1C subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium ulcerans glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Babesia bovis glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04853 calcium channel, voltage-dependent, L type, alpha 1F subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Toxoplasma gondii transporter, cation channel family protein Get druggable targets OG5_126791 All targets in OG5_126791
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130749 All targets in OG5_130749
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) mannose-6-phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Probable voltage-dependent R-type calcium channel subunit alpha-1E, putative Get druggable targets OG5_126791 All targets in OG5_126791
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans mannose-6-phosphate isomerase capable of functionally substituting for S. cerevisiae PMI40 (YER003C) Get druggable targets OG5_127555 All targets in OG5_127555
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Histone-lysine N-methyltransferase NSD3, putative Get druggable targets OG5_130029 All targets in OG5_130029
Leishmania major phosphomannose isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_127555 All targets in OG5_127555
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus multilocularis voltage dependent L type calcium channel subunit Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum Voltage-dependent P/Q-type calcium channel subunit alpha-1A, putative Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum ko:K00036 glucose-6-phosphate 1-dehydrogenase [EC1.1.1.49], putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Voltage-dependent calcium channel type D subunit alpha-1, putative Get druggable targets OG5_126791 All targets in OG5_126791
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Voltage-dependent P/Q-type calcium channel subunit alpha-1A, putative Get druggable targets OG5_126791 All targets in OG5_126791
Toxoplasma gondii phosphomannose isomerase type I protein Get druggable targets OG5_127555 All targets in OG5_127555
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum Voltage-dependent P/Q-type calcium channel subunit alpha-1A, putative Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma mansoni high voltage-activated calcium channel Cav2A Get druggable targets OG5_126791 All targets in OG5_126791
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_130029 All targets in OG5_130029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Muscle calcium channel subunit alpha-1, putative Get druggable targets OG5_126791 All targets in OG5_126791
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis voltage dependent calcium channel type d subunit Get druggable targets OG5_126791 All targets in OG5_126791
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Voltage-dependent calcium channel type D subunit alpha-1, putative Get druggable targets OG5_126791 All targets in OG5_126791
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Trypanosoma cruzi phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Brugia malayi glutaminase DH11.1 Get druggable targets OG5_129245 All targets in OG5_129245
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma congolense Voltage-dependent calcium channel subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Loa Loa (eye worm) voltage-dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei phosphomannose isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum mannose-6-phosphate isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum Voltage-dependent calcium channel type A subunit alpha-1, putative Get druggable targets OG5_126791 All targets in OG5_126791
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Treponema pallidum glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glutaminase, putative Get druggable targets OG5_129245 All targets in OG5_129245
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase Get druggable targets OG5_131193 All targets in OG5_131193
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_130029 All targets in OG5_130029
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04344 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04849 calcium channel, voltage-dependent, N type, alpha 1B subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Trypanosoma brucei gambiense phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans mannose-6-phosphate isomerase capable of functionally substituting for S. cerevisiae PMI40 (YER003C) Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum phosphomannose isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni SET domain protein Get druggable targets OG5_130029 All targets in OG5_130029
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania braziliensis phosphomannose isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus voltage dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus mannose 6 phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) glutaminase 2 Get druggable targets OG5_129245 All targets in OG5_129245
Echinococcus multilocularis voltage dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
Brugia malayi glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Get druggable targets OG5_131193 All targets in OG5_131193
Schistosoma japonicum Voltage-dependent calcium channel type A subunit alpha-1, putative Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 Get druggable targets OG5_126791 All targets in OG5_126791
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Trypanosoma brucei gambiense calcium channel protein, putative Get druggable targets OG5_126791 All targets in OG5_126791
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis 6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus voltage dependent calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma congolense phosphomannose isomerase, putative Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi mannose-6-phosphate isomerase, class I family protein Get druggable targets OG5_127555 All targets in OG5_127555
Plasmodium yoelii Phosphomannose isomerase type I, putative Get druggable targets OG5_127555 All targets in OG5_127555
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Brugia malayi mannose-6-phosphate isomerase, class I family protein Get druggable targets OG5_127555 All targets in OG5_127555
Plasmodium yoelii Glucose-6-phosphate dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania infantum glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi hypothetical protein Get druggable targets OG5_130749 All targets in OG5_130749
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum expressed protein Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative Get druggable targets OG5_130749 All targets in OG5_130749
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus multilocularis voltage dependent L type calcium channel subunit Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum protein with 4 PHD domains plus a SET domain and associated cysteine cluster at the C-terminus Get druggable targets OG5_130029 All targets in OG5_130029
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Plasmodium knowlesi glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum mannose-6-phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni mannose-6-phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma mansoni voltage-gated cation channel Get druggable targets OG5_126791 All targets in OG5_126791
Neospora caninum hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K04531 amyloid beta (A4) precursor protein-binding, family A, member 1, putative Get druggable targets OG5_130749 All targets in OG5_130749
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum expressed protein Get druggable targets OG5_126791 All targets in OG5_126791
Schistosoma japonicum Voltage-dependent N-type calcium channel subunit alpha-1B, putative Get druggable targets OG5_126791 All targets in OG5_126791
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K05302 histone-lysine N-methyltransferase [EC2.1.1.43], putative Get druggable targets OG5_130029 All targets in OG5_130029
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Babesia bovis phosphomannose isomerase type I family protein Get druggable targets OG5_127555 All targets in OG5_127555
Loa Loa (eye worm) mannose-6-phosphate isomerase Get druggable targets OG5_127555 All targets in OG5_127555
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) calcium channel Get druggable targets OG5_126791 All targets in OG5_126791
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Get druggable targets OG5_131193 All targets in OG5_131193
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA Get druggable targets OG5_127555 All targets in OG5_127555
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative Get druggable targets OG5_126791 All targets in OG5_126791
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) X11 protein Get druggable targets OG5_130749 All targets in OG5_130749
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126791 All targets in OG5_126791
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0047 0.0444 0.1031
Schistosoma mansoni glutaminase 0.033 0.3888 0.3888
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0619 0.0971
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0428 0.296
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0226 0.0276
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Schistosoma mansoni hypothetical protein 0.0494 0.5878 0.5878
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.027 0.027
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0675 0.0675
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0444 0.0543
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0234 0.0542
Brugia malayi hypothetical protein 0.0535 0.6375 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.0173 0.0272
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0619 0.0971
Brugia malayi nuclear receptor RXR 0.0029 0.0228 0.0357
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0154 0.037
Trichomonas vaginalis set domain proteins, putative 0.0288 0.3378 0.811
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1972 0.2408
Schistosoma mansoni nuclear receptor 0.0029 0.0228 0.0228
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5878 0.5878
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0047 0.0444 0.0697
Leishmania major DNA polymerase eta, putative 0.0077 0.0818 0.1899
Brugia malayi ecdysteroid receptor 0.0061 0.0619 0.0971
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0032 0.027 0.0423
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.027 0.0423
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0619 0.0619
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.4165 1
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0015 0.0059 0.0059
Brugia malayi nuclear receptor NHR-67 0.0029 0.0228 0.0357
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0357 0.0828
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0226 0.0276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0019 0.0108 0.017
Loa Loa (eye worm) calcium channel 0.0116 0.1288 0.202
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0228 0.0357
Toxoplasma gondii hypothetical protein 0.0021 0.0138 0.0866
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0619 0.0971
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0619 0.0619
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0238 0.0551
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0138 0.0018
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0357 0.0828
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0368 0.0577
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0108 0.0108
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0619 0.0971
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0154 0.0154
Echinococcus multilocularis Protein lozenge 0.0067 0.0693 0.0693
Echinococcus granulosus mannose 6 phosphate isomerase 0.0117 0.1304 0.1304
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0153 0.0975
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.1098 0.1098
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0769 0.0769
Onchocerca volvulus 0.0058 0.0578 0.0881
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0619 0.0971
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0619 0.0619
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0018 0.0042
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0684 0.8189 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0221 0.1538
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0117 0.1304 0.9518
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0108 0.0251
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0054 0.0531 0.1275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Trypanosoma brucei unspecified product 0.0032 0.0269 0.0624
Brugia malayi hypothetical protein 0.0011 0.0018 0.0028
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0221 0.0531
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0041 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0054 0.0125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Brugia malayi hypothetical protein 0.0011 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0028
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0769 0.1785
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0619 0.0619
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0113 0.1246 0.1246
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0341 0.0341
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0619 0.0946
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0173 0.0173
Toxoplasma gondii hypothetical protein 0.0059 0.0593 0.4153
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0108 0.0653
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0619 0.0971
Trichomonas vaginalis rotamase, putative 0.0039 0.0357 0.0856
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0154 0.0358
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5878 0.5878
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0113 0.1246 0.1521
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0226 0.0127
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Schistosoma mansoni hepatoma derived growth factor 0.0011 0.0018 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0226 0.0354
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0818 0.1283
Loa Loa (eye worm) hypothetical protein 0.0023 0.0153 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0125 0.1402 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0228 0.0228
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0226 0.0276
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0238 0.0551
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0619 0.0619
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0269 0.0624
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0023 0.0153 0.0153
Leishmania major phosphomannose isomerase 0.0117 0.1304 0.3028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0228 0.0357
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0444 0.0397
Onchocerca volvulus 0.0288 0.3378 0.5286
Echinococcus multilocularis cpg binding protein 0.0037 0.0323 0.0323
Onchocerca volvulus 0.0061 0.0619 0.0946
Loa Loa (eye worm) PWWP domain-containing protein 0.0011 0.0018 0.0028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0549 0.0861
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0113 0.1246 0.1954
Mycobacterium ulcerans hypothetical protein 0.003 0.0238 0.029
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0116 0.1288 0.202
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0228 0.0228
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0578 0.0906
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1264 0.2933
Giardia lamblia Sgs1 DNA helicase, putative 0.0023 0.0153 0.0367
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.017
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0501 0.1163
Echinococcus granulosus PWWP domain containing protein 2A 0.0011 0.0018 0.0018
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.027 0.027
Onchocerca volvulus 0.0029 0.0226 0.0327
Trypanosoma brucei transcription elongation factor s-II, putative 0.0011 0.0018 0.0041
Echinococcus multilocularis voltage dependent calcium channel 0.0116 0.1288 0.1288
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.0341 0.0341
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.01 0.1093 0.1093
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0765 0.0765
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0018 0.0003
Leishmania major DNA damage repair protein, putative 0.0014 0.0054 0.0125
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.4308 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0619 0.0619
Brugia malayi ecdysone receptor 0.0029 0.0228 0.0357
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Echinococcus multilocularis citrate lyase subunit beta protein 0.003 0.0238 0.0238
Schistosoma mansoni hepatoma derived growth factor 0.0011 0.0018 0.0018
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0039 0.0061
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0221 0.1273
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0138 0.064
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0769 0.0769
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.1368 0.3284
Loa Loa (eye worm) hypothetical protein 0.0032 0.027 0.0423
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.017
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.01 0.1093 0.1714
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0804 0.0804
Treponema pallidum licC protein (licC) 0.0125 0.1402 0.3366
Echinococcus granulosus cpg binding protein 0.0037 0.0323 0.0323
Loa Loa (eye worm) glutaminase 0.033 0.3888 0.6099
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0018
Brugia malayi jmjC domain containing protein 0.0019 0.0108 0.017
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0234 0.0561
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0619 0.0971
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0619 0.0619
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0238 0.029
Trypanosoma brucei chrX additional, unordered contigs 0.0014 0.0054 0.0125
Schistosoma mansoni apoptosis regulator bax 0.01 0.1093 0.1093
Mycobacterium ulcerans glutaminase 0.033 0.3888 0.4747
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0619 0.0619
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.1098 0.1098
Loa Loa (eye worm) hypothetical protein 0.0535 0.6375 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0108 0.0108
Echinococcus multilocularis peregrin 0.0011 0.0018 0.0018
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0619 0.0619
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0117 0.1304 0.1304
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0619 0.0619
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0675 0.1058
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0444 0.1031
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0173 0.1124
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0578 0.0578
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0037 0.0331 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0564 0.1354
Trichomonas vaginalis DNA polymerase eta, putative 0.0047 0.0444 0.1067
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0619 0.0946
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1972 0.2292
Echinococcus granulosus voltage dependent calcium channel 0.0116 0.1288 0.1288
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0011 0.0018 0.0041
Echinococcus multilocularis voltage dependent calcium channel 0.0116 0.1288 0.1288
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0108 0.017
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0228 0.0357
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0228 0.033
Mycobacterium ulcerans hypothetical protein 0.0125 0.1402 0.1712
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0741 0.0741
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0226 0.0543
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0444 0.0543
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0769 0.0939
Echinococcus multilocularis hepatoma derived growth factor protein 0.0011 0.0018 0.0018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.1402 0.1585
Brugia malayi mbt repeat family protein 0.0058 0.0578 0.0906
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0741 0.0741
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0619 0.0971
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0234 0.0542
Onchocerca volvulus 0.01 0.1098 0.1699
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0042 0.0384 0.0384
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.4165 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0226 0.0525
Loa Loa (eye worm) hypothetical protein 0.01 0.1098 0.1722
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0116 0.1288 0.1288
Loa Loa (eye worm) hypothetical protein 0.0066 0.0675 0.1058
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0108 0.0108
Schistosoma mansoni phd finger protein 0.0011 0.0018 0.0018
Trichomonas vaginalis rotamase, putative 0.004 0.0368 0.0884
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0039 0.0353 0.0284
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0228 0.0357
Trypanosoma cruzi phosphomannose isomerase, putative 0.0117 0.1304 0.3028
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0064 0.0651 0.0795
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0228 0.0228
Brugia malayi Pre-SET motif family protein 0.0038 0.0341 0.0536
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0675 0.0675
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0769 0.0769
Schistosoma mansoni cpg binding protein 0.0037 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0024 0.0173 0.0272
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0054 0.0303
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0116 0.1288 0.1288
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0074 0.0772 0.0942
Onchocerca volvulus 0.0029 0.0228 0.033
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.2999 0.696
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.4308 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0138 0.0169
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0036 0.0318 0.0739
Brugia malayi glucose-6-phosphate dehydrogenase 0.0113 0.1246 0.1954
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0221 0.027
Brugia malayi nuclear hormone receptor 0.0061 0.0619 0.0971
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0018 0.0042
Mycobacterium ulcerans hypothetical protein 0.0029 0.0226 0.0276
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0154 0.0242
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.1975 0.4584
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0113 0.1246 0.2892
Loa Loa (eye worm) glutaminase 2 0.033 0.3888 0.6099
Onchocerca volvulus 0.0035 0.0299 0.0443
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0226 0.0354
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0444 0.1031
Loa Loa (eye worm) hypothetical protein 0.008 0.0846 0.1327
Brugia malayi mbt repeat family protein 0.0058 0.0578 0.0906
Brugia malayi glutaminase DH11.1 0.033 0.3888 0.6099
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0116 0.1288 0.1288
Schistosoma mansoni cpg binding protein 0.0037 0.0323 0.0323
Brugia malayi hypothetical protein 0.008 0.0846 0.1327
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0226 0.0276
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0123 0.1368 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.1264 0.2933
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0015 0.0059 0.0059
Schistosoma mansoni kinase 0.0058 0.0582 0.0582
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0018 0.0044
Schistosoma mansoni rotamase 0.004 0.0368 0.0368
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0108 0.0251
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0054 0.0261
Trypanosoma brucei phosphomannose isomerase 0.0117 0.1304 0.3028
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.1264 0.1982
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0501 0.1163
Mycobacterium ulcerans hypothetical protein 0.0192 0.2212 0.2701
Trypanosoma brucei polo-like protein kinase 0.0114 0.1264 0.2933
Brugia malayi tailless protein 0.0029 0.0228 0.0357
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0217
Brugia malayi nuclear receptor NHR-88 0.0061 0.0619 0.0971
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0619 0.0619
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0341 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Loa Loa (eye worm) apoptosis regulator protein 0.01 0.1093 0.1714
Trypanosoma cruzi phosphomannose isomerase, putative 0.0117 0.1304 0.3028
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Leishmania major hypothetical protein, conserved 0.0019 0.0108 0.0251
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0769 0.08
Echinococcus granulosus dna polymerase kappa 0.0047 0.0444 0.0444
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0023 0.0153 0.0153
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0154 0.1042
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0117 0.1304 0.2046
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0221 0.027
Brugia malayi hypothetical protein 0.0029 0.0228 0.0357
Mycobacterium tuberculosis Conserved protein 0.003 0.0238 0.0141
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.1264 0.3034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0619 0.0971
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0226 0.0276
Echinococcus granulosus PWWP domain containing protein 2A 0.0011 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0216
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0619 0.0619
Echinococcus multilocularis dna polymerase kappa 0.0047 0.0444 0.0444
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0123 0.1368 0.3284
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0138 0.0924
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0113 0.1246 0.1246
Brugia malayi jmjC domain containing protein 0.0019 0.0108 0.017
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0071 0.0736 0.1708
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0116 0.1288 0.1288
Schistosoma mansoni lozenge 0.0067 0.0693 0.0693
Echinococcus multilocularis bloom syndrome protein 0.0055 0.0543 0.0543
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0769 0.0939
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0027 0.0063
Trypanosoma brucei unspecified product 0.0032 0.0269 0.0624
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0228 0.0228
Brugia malayi PWWP domain containing protein 0.0011 0.0018 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0054 0.0125
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0108 0.0108
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0041 0.0041
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0741 0.0741
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0619 0.0619
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.003 0.0238 0.029
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0153 0.024
Brugia malayi CXXC zinc finger family protein 0.0035 0.0299 0.047
Giardia lamblia Kinase, PLK 0.0114 0.1264 0.3034
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0238 0.0551
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0228 0.0357
Loa Loa (eye worm) hypothetical protein 0.0014 0.0054 0.0085
Trichomonas vaginalis Citrate lyase beta chain, putative 0.003 0.0238 0.057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0619 0.0971
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0116 0.1288 0.1288
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0549 0.0549
Schistosoma mansoni DNA helicase recq1 0.0023 0.0153 0.0153
Entamoeba histolytica phosphomannose isomerase, putative 0.0117 0.1304 0.3132
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0228 0.0228
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0226 0.0525
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0226 0.0276
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0619 0.0619
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0113 0.1246 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0154 0.0242
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0038 0.0341 0.0341
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0042 0.0384 0.0384
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.1098 0.1722
Schistosoma mansoni SET domain protein 0.0042 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0619 0.0971
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0027 0.0063
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0684 0.8189 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0228 0.0228
Onchocerca volvulus 0.0038 0.0341 0.0509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0765 0.0765
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0138 0.1108
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0619 0.0971
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0015 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0549 0.0549
Toxoplasma gondii exonuclease III APE 0.0023 0.0154 0.0984
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0054 0.0125
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0619 0.0619
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0023 0.0153 0.0153
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0043
Schistosoma mansoni ap endonuclease 0.0023 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0058 0.0578 0.0906
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0013 0.0031
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.1402 0.1585
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0564 0.1354
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0578 0.0881
Mycobacterium ulcerans hypothetical protein 0.0125 0.1402 0.1712
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0578 0.0578
Mycobacterium ulcerans hypothetical protein 0.0014 0.0054 0.0066
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0357 0.0828
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0228 0.0357
Loa Loa (eye worm) hypothetical protein 0.0116 0.1288 0.202
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0619 0.0971
Leishmania major hypothetical protein, conserved 0.0257 0.2999 0.696
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0154 0.0154
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0549 0.0861
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.027 0.0423
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0549 0.0549
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0228 0.0228
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0154 0.037
Leishmania major DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0232 0.2691 0.2691
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.1264 0.1264
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0228 0.0357
Onchocerca volvulus 0.0535 0.6375 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.1368 0.3284
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.01 0.1093 0.1093
Echinococcus granulosus bloom syndrome protein 0.0055 0.0543 0.0543
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4165 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0549 0.0549
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0108 0.0108
Schistosoma mansoni ap endonuclease 0.0023 0.0154 0.0154
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0228 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0619 0.0971
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Brugia malayi jmjC domain containing protein 0.0019 0.0108 0.017
Trichomonas vaginalis glutaminase, putative 0.033 0.3888 0.9334
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0041 0.0041
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0154 0.037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0619 0.0971
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0108 0.0653
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0226 0.0543
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0619 0.0619
Schistosoma mansoni DNA helicase recq5 0.0023 0.0153 0.0153
Giardia lamblia DNA damage repair protein 0.0014 0.0054 0.0129
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0047 0.0444 0.0444
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0011 0.0018 0.0041
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0117 0.1304 0.2046
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.01 0.1093 0.1093
Trypanosoma brucei unspecified product 0.0047 0.0444 0.1031
Entamoeba histolytica hypothetical protein 0.0028 0.0221 0.0531
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0221 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Schistosoma mansoni blooms syndrome DNA helicase 0.0043 0.0403 0.0403
Echinococcus granulosus citrate lyase subunit beta protein 0.003 0.0238 0.0238
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.4308 1
Echinococcus granulosus phd:f box containing protein 0.0019 0.0108 0.0108
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0108 0.0414
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0619 0.0619
Echinococcus multilocularis PWWP domain containing protein 2A 0.0011 0.0018 0.0018
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0765 0.12
Schistosoma mansoni voltage-gated cation channel 0.0116 0.1288 0.1288
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0619 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0023 0.0153 0.0752
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0619 0.0619
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0221 0.027
Mycobacterium ulcerans hypothetical protein 0.003 0.0238 0.029
Giardia lamblia DINP protein human, muc B family 0.0047 0.0444 0.1067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0619 0.0971
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0357 0.0856
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0054 0.0125
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0018 0.0018
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0226 0.0543
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0054 0.0125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0228 0.033
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0769 0.0769
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.027 0.027
Onchocerca volvulus 0.0013 0.0037 0.003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0038 0.0341 0.0341
Echinococcus granulosus hepatoma derived growth factor protein 0.0011 0.0018 0.0018
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0154 0.0358
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0578 0.0578
Leishmania major DNA polymerase eta, putative 0.0045 0.0428 0.0992
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0047 0.0444 0.1067
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0047 0.0444 0.0444
Echinococcus multilocularis expressed protein 0.004 0.0368 0.0368
Loa Loa (eye worm) MBCTL1 0.0066 0.0675 0.1058
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0216
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1972 0.2408
Loa Loa (eye worm) X11 protein 0.0083 0.0886 0.1389
Brugia malayi steroid hormone receptor 0.0061 0.0619 0.0971
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0619 0.0971
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0117 0.1304 0.1593
Loa Loa (eye worm) hypothetical protein 0.0029 0.0226 0.0354
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0619 0.0971
Schistosoma mansoni cpg binding protein 0.0035 0.0299 0.0299
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0769 0.0939
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0228 0.0228
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0221 0.0121
Echinococcus multilocularis sodium channel protein 0.0049 0.0476 0.0476
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0027 0.0063
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0323 0.2202
Echinococcus multilocularis amyloid beta A4 protein 0.0083 0.0886 0.0886
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.027 0.027
Brugia malayi hypothetical protein 0.0032 0.027 0.0423
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0132 0.0132
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.03 0.03
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.1264 0.196
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0221 0.1469
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.003 0.0238 0.0141
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0299 0.047
Schistosoma mansoni zinc finger protein 0.0029 0.0228 0.0228
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.01 0.1093 0.1714
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0226 0.0354
Plasmodium vivax JmjC domain containing protein 0.0019 0.0108 0.0704
Loa Loa (eye worm) hypothetical protein 0.0077 0.0818 0.1283
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0619 0.0619
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0226 0.0276
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0619 0.0619
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0226 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0549 0.0549
Plasmodium vivax SET domain protein, putative 0.0038 0.0341 0.2425
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0221 0.1775
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0619 0.0619
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0765 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1264 0.1264
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0027 0.0063
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0228 0.0357
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0221 0.1469
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0113 0.1246 0.2991
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0023 0.0153 0.0153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0619 0.0619
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0154 0.0155
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0619 0.0946
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Leishmania major hypothetical protein, conserved 0.0011 0.0018 0.0041
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0228 0.0228
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0232 0.2691 0.2691
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0116 0.1288 0.1288
Trichomonas vaginalis DNA helicase recq1, putative 0.0055 0.0543 0.1304
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0684 0.8189 1
Onchocerca volvulus 0.0029 0.0228 0.033
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Brugia malayi nuclear receptor RXR 0.0032 0.027 0.0423
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0054 0.0125
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.0054 0.0261
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0578 0.0578
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.2212 0.2588
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0619 0.0619
Echinococcus granulosus peregrin 0.0011 0.0018 0.0018
Loa Loa (eye worm) DR-78 0.0029 0.0228 0.0357
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0116 0.1288 0.1288
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0221 0.0513
Toxoplasma gondii phosphomannose isomerase type I protein 0.0117 0.1304 0.9294
Schistosoma mansoni DNA polymerase eta 0.0077 0.0818 0.0818
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0228 0.0228
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0153 0.024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0226 0.0354
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0368 0.0577
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0368 0.0884
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0108 0.0108
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0154 0.0762
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0228 0.0228
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.1246 0.2892
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0444 0.1031
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.4308 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0619 0.0971
Treponema pallidum ATP-dependent DNA helicase 0.0012 0.0018 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0154 0.0358
Schistosoma mansoni amyloid beta A4 protein related 0.0083 0.0886 0.0886
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.01 0.1093 0.1093
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.1264 0.1982
Brugia malayi conserved hypotetical protein 0.0029 0.0228 0.0357
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0071 0.0736 0.1708
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0123 0.1368 0.3284
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0154 0.037
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0117 0.1304 0.2046
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0578 0.0578
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0154 0.037
Echinococcus granulosus dna polymerase eta 0.0077 0.0818 0.0818
Loa Loa (eye worm) hypothetical protein 0.0029 0.0226 0.0354
Schistosoma mansoni terminal deoxycytidyl transferase 0.0047 0.0444 0.0444
Brugia malayi nuclear hormone receptor 0.0029 0.0228 0.0357
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0228 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0154 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0054 0.0125
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0971
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0113 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0166 0.19 0.2981
Echinococcus multilocularis dna polymerase eta 0.0077 0.0818 0.0818
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0675 0.0675
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.1246 0.2892
Brugia malayi hypothetical protein 0.0032 0.027 0.0423
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0228 0.0228
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0023 0.0153 0.024
Schistosoma mansoni hypothetical protein 0.01 0.1093 0.1093
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.0818 0.1899
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0269 0.0624
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0154 0.0037
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0226 0.0276
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.0341 0.0341
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.1098 0.1098
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.2999 0.696
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0108 0.017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.2956 0.4637
Schistosoma mansoni coup transcription factor 0.0061 0.0619 0.0619
Loa Loa (eye worm) RecQ helicase 0.0055 0.0543 0.0852
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0769 0.5425
Loa Loa (eye worm) hypothetical protein 0.0032 0.027 0.0423
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0037 0.0328 0.2326
Loa Loa (eye worm) hypothetical protein 0.0038 0.0341 0.0536
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0228 0.0228
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0708 0.4989
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0675 0.0675
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0619 0.0619
Schistosoma mansoni hypothetical protein 0.01 0.1093 0.1093
Schistosoma mansoni hypothetical protein 0.0355 0.4187 0.4187
Brugia malayi polk-prov protein 0.0014 0.0054 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0018 0.0041
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0444 0.0697
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0125 0.1402 0.1712
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0011 0.0018 0.0041
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0064 0.0651 0.0654
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0015 0.0015
Schistosoma mansoni SET domain protein 0.0017 0.0083 0.0083
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4165 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0049 0.0476 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0637 0.1479
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0341 0.0341
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.1264 0.1264
Loa Loa (eye worm) hypothetical protein 0.0535 0.6375 1
Leishmania major DNA polymerase kappa, putative 0.0014 0.0054 0.0125
Echinococcus granulosus expressed protein 0.004 0.0368 0.0368
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0108 0.0108
Entamoeba histolytica deoxycytidyl transferase, putative 0.0047 0.0444 0.1067
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0074 0.0772 0.5444
Brugia malayi hypothetical protein 0.0029 0.0228 0.0357
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Loa Loa (eye worm) runx1 0.0067 0.0693 0.1087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0619 0.0971
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0028
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0226 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.027 0.0423
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0116 0.1288 0.1288
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.027 0.0423
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0047 0.0444 0.0444
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0108 0.017
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0018
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0048 0.0463 0.311
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1264 0.2933
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0357 0.0828
Loa Loa (eye worm) hypothetical protein 0.0032 0.027 0.0423
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.2999 0.696
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0123 0.1368 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0234 0.0542
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0154 0.0358
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0038 0.0341 0.2337
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0217
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.0818 0.1899
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1264 0.3034
Brugia malayi jmjC domain containing protein 0.0073 0.0765 0.12
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0117 0.1304 0.9533
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0116 0.1288 0.1288
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0108 0.0108
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0549 0.0549
Schistosoma mansoni hypothetical protein 0.01 0.1093 0.1093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0675 0.0675
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.01 0.1093 0.1093
Brugia malayi nuclear receptor NHR-88 0.0029 0.0228 0.0357
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0074 0.0779 0.1222
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0117 0.1304 0.3132
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0501 0.1163
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0021 0.0138 0.0217
Schistosoma mansoni nuclear receptor 0.0029 0.0228 0.0228
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0054 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0619 0.0971
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0108 0.0108
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0221 0.0513
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1975 0.4584
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0501 0.1163
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0619 0.0971
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1975 0.4584
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0123 0.1368 0.9751
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0684 0.8189 1
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0238 0.029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0619 0.0619
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0619 0.0619
Echinococcus multilocularis PWWP domain containing protein 2A 0.0011 0.0018 0.0018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0619 0.0971
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0054 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Brugia malayi jmjC domain containing protein 0.0071 0.0741 0.1162
Loa Loa (eye worm) hypothetical protein 0.0029 0.0228 0.0357
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0132 0.0132
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0108 0.0251
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Brugia malayi Pre-SET motif family protein 0.0253 0.2956 0.4637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4165 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0054 0.0125
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0444 0.1031
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0428 0.0992
Echinococcus granulosus amyloid beta A4 protein 0.0083 0.0886 0.0886
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0027 0.0068
Entamoeba histolytica recQ family helicase, putative 0.0029 0.0234 0.0561
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0117 0.1304 0.2046
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0619 0.0619
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0549 0.0549
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0578 0.0578
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0578 0.0578
Schistosoma mansoni mannose-6-phosphate isomerase 0.0117 0.1304 0.1304
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0153 0.0975
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0269 0.0624
Trichomonas vaginalis DNA helicase recq, putative 0.0055 0.0543 0.1304
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0619 0.0619
Brugia malayi Bloom's syndrome protein homolog 0.0055 0.0543 0.0852
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0047 0.0444 0.0397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0619 0.0971
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0226 0.0525
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0357 0.2447

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) 0.635 uM PubChem BioAssay. Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 3.27 uM PUBCHEM_BIOASSAY: uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay. Confirmatory Screen for inhibitors of association between Mint1-PDZ domains and N-type Ca2+ channel carboxyl-terminal peptide (NC peptide). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2093, AID2489, AID2496, AID434980] ChEMBL. No reference
IC50 (functional) = 4.444139919 um PUBCHEM_BIOASSAY: Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1022 (Primary screen preceding this dose-response assay.)] ChEMBL. No reference
IC50 (binding) = 10.8 um PUBCHEM_BIOASSAY: Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay. Confirmatory Screen for inhibitors of association between Mint1-PDZ domains and N-type Ca2+ channel carboxyl-terminal peptide (NC peptide). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 12.081 um PUBCHEM_BIOASSAY: HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate. (Class of assay: confirmatory) [Related pubchem assays: 1209 ] ChEMBL. No reference
IC50 (functional) = 13.6 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (binding) = 19.29 um PUBCHEM_BIOASSAY: Inhibitors of Mycobacterial Glucosamine-1-phosphate acetyl transferase (GlmU). Secondary screen. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 23.37 uM PUBCHEM_BIOASSAY: Primary and Confirmatory Screening for Flavivirus Genomic Capping Enzyme Inhibition. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588708, AID588742] ChEMBL. No reference
IC50 (functional) = 54.6 uM PUBCHEM_BIOASSAY: Dose Response orthogonal kinetic assay utilizing the direct detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) 64 uM PUBCHEM_BIOASSAY: Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID782] ChEMBL. No reference
IC50 (functional) = 67.4 uM PUBCHEM_BIOASSAY: Dose Response orthogonal assay utilizing the direct end-point detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) = 79.2 uM PUBCHEM_BIOASSAY: Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
Potency (functional) 1.4125 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 5.6101 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 5.6234 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.7016 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) 8.9125 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Primary screen confirmation. (Class of assay: confirmatory) [Related pubchem assays: 2451, 2472, 2464 ] ChEMBL. No reference
Potency (functional) 10.6213 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.9173 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 13.4591 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 19.0115 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 26.8545 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Rabbit FBPA Selectivity. (Class of assay: confirmatory) [Related pubchem assays: 2451, 2472, 2464 ] ChEMBL. No reference
Potency (functional) 42.5615 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 47.7548 uM PubChem BioAssay. qHTS Assay for the Inhibitors of FEN1: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) = 63.0957 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen confirmation. (Class of assay: confirmatory) [Related pubchem assays: 2451, 2472, 2464 ] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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