Detailed information for compound 1730726

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.493 | Formula: C26H23N5O2
  • H donors: 2 H acceptors: 4 LogP: 4.99 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)nc(n2c1ccnc(n1)NC1CCOCC1)c1ccc2c(c1)cccc2
  • InChi: 1S/C26H23N5O2/c32-21-7-8-23-22(16-21)29-25(19-6-5-17-3-1-2-4-18(17)15-19)31(23)24-9-12-27-26(30-24)28-20-10-13-33-14-11-20/h1-9,12,15-16,20,32H,10-11,13-14H2,(H,27,28,30)
  • InChiKey: XOZSAGRTIVKDDL-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens mitogen-activated protein kinase 10 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
Echinococcus granulosus c-Jun N-terminal kinases Get druggable targets OG5_129677 All targets in OG5_129677
Schistosoma japonicum ko:K04440 c-Jun N-terminal kinase, putative Get druggable targets OG5_129677 All targets in OG5_129677
Brugia malayi Stress-activated protein kinase jnk-1 Get druggable targets OG5_129677 All targets in OG5_129677
Schistosoma japonicum IPR000164,Histone H3;IPR009072,Histone-fold,domain-containing Get druggable targets OG5_129677 All targets in OG5_129677
Echinococcus multilocularis c Jun NH2 terminal kinase Get druggable targets OG5_129677 All targets in OG5_129677

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Schistosoma mansoni cpg binding protein 0.0013 0.0095 0.0116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.002 0.0193 0.023
Plasmodium falciparum tubulin delta chain, putative 0.015 0.2003 0.2489
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0029 0.0321 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Echinococcus granulosus tubulin alpha 1C chain 0.0437 0.5967 0.747
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0178 0.0223
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0024 0.0259 0.0324
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Entamoeba histolytica cysteine protease, putative 0.0007 0.0023 0.0021
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.015 0.2003 1
Giardia lamblia hypothetical protein 0.0011 0.0072 0.0065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0407
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.002 0.0204 0.0719
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0016 0.0138 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis beta tubulin 0.0583 0.7988 0.7988
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0047 0.0575 0.2169
Schistosoma mansoni nephrin 0.0012 0.0083 0.0102
Loa Loa (eye worm) alpha-tubulin 0.0437 0.5967 0.747
Loa Loa (eye worm) tubulin beta chain 0.015 0.2003 0.2508
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0007 0.002 0.001
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Brugia malayi hypothetical protein 0.0103 0.1354 0.1692
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0466 0.0466
Trypanosoma cruzi beta tubulin, putative 0.0583 0.7988 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0007 0.002 0.0019
Echinococcus multilocularis isocitrate dehydrogenase 0.002 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0007 0.0023 0.0028
Loa Loa (eye worm) TK protein kinase 0.0018 0.0172 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0466 0.0581
Schistosoma mansoni hypothetical protein 0.0045 0.0548 0.0683
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.1405 0.1759
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0107
Entamoeba histolytica tubulin alpha-1 chain 0.0437 0.5967 0.7469
Echinococcus multilocularis Niemann Pick C1 protein 0.0127 0.1684 0.1684
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trypanosoma cruzi tubulin delta chain 0.0296 0.4025 0.5036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0466 0.0584
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0008 0.0028 0.0041
Schistosoma mansoni aryl hydrocarbon receptor 0.0021 0.0216 0.0268
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0007 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.002 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Brugia malayi alpha-tubulin 0.0437 0.5967 0.747
Plasmodium falciparum tubulin gamma chain 0.0352 0.4797 0.5995
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.002 0.0204 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0024 0.0259 0.0259
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0209 0.0262
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0193 0.0235
Loa Loa (eye worm) tubulin beta-4 chain 0.0583 0.7988 1
Trypanosoma cruzi alpha tubulin, putative 0.0437 0.5967 0.7469
Plasmodium vivax tubulin beta chain, putative 0.0583 0.7988 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0369 0.0369
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0107
Echinococcus multilocularis tumor protein p63 0.0148 0.1968 0.1968
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Mycobacterium ulcerans cell division protein FtsZ 0.015 0.2003 1
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0204 0.0244
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Onchocerca volvulus 0.0008 0.0028 0.0023
Plasmodium vivax vivapain-2 0.0007 0.0023 0.0021
Toxoplasma gondii cathepsin CPL 0.0007 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Brugia malayi Smad1 0.0007 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0404
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0178 0.022
Trypanosoma cruzi zeta tubulin, putative 0.0394 0.5383 0.6737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Brugia malayi hypothetical protein 0.0021 0.0209 0.0259
Loa Loa (eye worm) thioredoxin reductase 0.0021 0.0208 0.026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0108 0.0108
Plasmodium vivax tubulin alpha chain, putative 0.0437 0.5967 0.7469
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0193 0.0235
Echinococcus granulosus Niemann Pick C1 protein 0.0182 0.2441 0.3056
Brugia malayi sulfakinin receptor protein 0.0098 0.1275 0.1593
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0212 0.025
Loa Loa (eye worm) TK/EGFR protein kinase 0.0132 0.1751 0.2192
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) tubulin beta-2A chain 0.0583 0.7988 1
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Entamoeba histolytica recQ family DNA helicase 0.0006 0.001 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0369 0.0462
Loa Loa (eye worm) Smad1 0.0007 0.0022 0.0028
Echinococcus multilocularis dnaJ subfamily B 0.0179 0.2399 0.2399
Echinococcus granulosus cathepsin l cysteine peptidase 0.0007 0.0023 0.0028
Schistosoma mansoni Smad4 0.0007 0.0022 0.0025
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0085 0.0103
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Loa Loa (eye worm) hypothetical protein 0.0286 0.3885 0.4864
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0052 0.0647 0.2455
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Schistosoma mansoni tubulin subunit delta 0.015 0.2003 0.2506
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0212 0.0254
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.1063 0.1331
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0013 0.0095 0.0095
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0124 0.0155
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0075 0.0955 0.1195
Toxoplasma gondii tubulin, putative 0.0023 0.0244 0.0294
Echinococcus multilocularis agrin 0.0017 0.0152 0.0152
Toxoplasma gondii alpha tubulin TUBA1 0.0437 0.5967 0.7467
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Trichomonas vaginalis tubulin beta chain, putative 0.0583 0.7988 1
Echinococcus granulosus tubulin beta 4A class IVa 0.0583 0.7988 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0006 0.0002 0.0003
Brugia malayi protein-tyrosine kinase 0.0018 0.0172 0.0213
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Brugia malayi glutathione reductase 0.0021 0.0208 0.0257
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0055 0.0684 0.0684
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0008 0.0036 0.0036
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0466 0.0584
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0021 0.0213 0.0263
Echinococcus multilocularis Immunoglobulin 0.0009 0.0048 0.0048
Brugia malayi hypothetical protein 0.0071 0.091 0.1137
Brugia malayi glutaminase DH11.1 0.0108 0.1419 0.1774
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0119 0.1567 0.1961
Trichomonas vaginalis esterase, putative 0.003 0.0337 0.0406
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0466 0.0584
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Brugia malayi Tubulin alpha chain 0.0437 0.5967 0.747
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Onchocerca volvulus 0.0178 0.2388 1
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0024 0.0259 0.0324
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0085 0.0106
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0011 0.0069 0.0198
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0212 0.0965
Echinococcus granulosus tubulin alpha 1C chain 0.0437 0.5967 0.747
Brugia malayi MH1 domain containing protein 0.0007 0.0022 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Brugia malayi tubulin alpha-2 chain 0.0437 0.5967 0.747
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Loa Loa (eye worm) ctsf protein 0.0007 0.0023 0.0028
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi Kelch motif family protein 0.0079 0.101 0.1262
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0047 0.0575 0.2169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Schistosoma mansoni lamin 0.0012 0.0085 0.0103
Schistosoma mansoni tyrosine kinase 0.0093 0.1204 0.1505
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0025 0.0269 0.0334
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0032 0.0369 0.0438
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Echinococcus multilocularis tubulin alpha 1C chain 0.0437 0.5967 0.5967
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0209 0.0259
Brugia malayi protein C24B5.3 0.0008 0.0028 0.0032
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0075 0.0955 0.1193
Echinococcus multilocularis GPCR, family 2 0.0014 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0067 0.0848 0.1062
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0466 0.0581
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0193 0.0242
Brugia malayi Furin-like cysteine rich region family protein 0.0132 0.1751 0.219
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Mycobacterium tuberculosis Probable reductase 0.0047 0.0575 0.2169
Trypanosoma brucei alpha tubulin, putative 0.0178 0.2388 0.2978
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0008 0.0028 0.0032
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Brugia malayi beta-lactamase family protein 0.003 0.0337 0.0419
Schistosoma mansoni tubulin subunit epsilon 0.0352 0.4792 0.5998
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0269 0.0336
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.002 0.0193 0.023
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0123
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0466 0.0581
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Brugia malayi Cell division protein ftsZ 0.015 0.2003 0.2506
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0021 0.0213 0.0264
Brugia malayi Tubulin beta chain 0.015 0.2003 0.2506
Loa Loa (eye worm) hypothetical protein 0.0259 0.3501 0.4383
Loa Loa (eye worm) tubulin alpha 2 0.0286 0.3885 0.4864
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.008
Schistosoma mansoni follistatin 0.0017 0.0152 0.0187
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0131
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Brugia malayi hypothetical protein 0.001 0.0065 0.0079
Trypanosoma cruzi epsilon tubulin, putative 0.0352 0.4792 0.5997
Schistosoma mansoni tyrosine kinase 0.0008 0.0036 0.0042
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0212 0.0212
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0178 0.0223
Mycobacterium tuberculosis Probable oxidoreductase 0.0052 0.0647 0.2455
Mycobacterium leprae Probable lipase LipE 0.003 0.0337 0.1402
Giardia lamblia Tenascin-37 0.0011 0.0072 0.0065
Toxoplasma gondii transporter, major facilitator family protein 0.0024 0.0259 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Echinococcus granulosus geminin 0.0219 0.2956 0.3701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Trypanosoma cruzi zeta tubulin, putative 0.0394 0.5383 0.6737
Schistosoma mansoni hypothetical protein 0.0032 0.0368 0.0458
Onchocerca volvulus 0.001 0.0065 0.0178
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0029 0.0321 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0466 0.0581
Schistosoma mansoni integrin alpha-ps 0.0058 0.072 0.0899
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Trypanosoma cruzi tubulin delta chain 0.0296 0.4025 0.5036
Schistosoma mansoni cell adhesion molecule 0.0012 0.0084 0.0102
Loa Loa (eye worm) hypothetical protein 0.001 0.0066 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi nuclear hormone receptor 0.0019 0.0178 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0082 0.0087
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0009 0.0048 0.0048
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0021 0.0208 0.0733
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0193 0.0226
Entamoeba histolytica tubulin family protein 0.0583 0.7988 1
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0278 0.3775 0.3775
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Loa Loa (eye worm) tubulin alpha 2 0.0108 0.1419 0.1776
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0193 0.0227
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0209 0.0259
Trichomonas vaginalis tubulin, putative 0.0178 0.2388 0.2978
Loa Loa (eye worm) glutaminase 0.0108 0.1419 0.1777
Onchocerca volvulus 0.0024 0.0259 0.0999
Trypanosoma cruzi cysteine peptidase, putative 0.0007 0.0023 0.0021
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0178 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0065 0.0174
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0466 0.0581
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus granulosus Smad4 0.0007 0.0022 0.0028
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0071 0.0904 0.1132
Onchocerca volvulus 0.0024 0.0259 0.0999
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0373 0.046
Onchocerca volvulus 0.0013 0.0095 0.0307
Loa Loa (eye worm) hypothetical protein 0.012 0.1577 0.1975
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0011 0.0069 0.0079
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0369 0.0369
Plasmodium falciparum thioredoxin reductase 0.0021 0.0208 0.0235
Loa Loa (eye worm) hypothetical protein 0.0012 0.0085 0.0106
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Leishmania major beta tubulin 0.0583 0.7988 1
Mycobacterium ulcerans beta-lactamase 0.003 0.0337 0.1594
Schistosoma mansoni tubulin subunit alpha 0.015 0.2003 0.2506
Schistosoma mansoni nuclear receptor 0.0019 0.0178 0.022
Mycobacterium leprae cell division protein FtsZ 0.015 0.2003 1
Echinococcus multilocularis integrin beta 2 0.0378 0.5149 0.5149
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0512 0.0641
Echinococcus granulosus c-Jun N-terminal kinases 0.0278 0.3775 0.4726
Giardia lamblia GTOR 0.002 0.0193 0.0217
Echinococcus granulosus defective proboscis extension response 0.0009 0.0048 0.006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.002 0.0204 0.0248
Plasmodium falciparum glutathione reductase 0.0021 0.0208 0.0235
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Loa Loa (eye worm) integrin alpha pat-2 0.0198 0.2667 0.3339
Echinococcus granulosus Immunoglobulin 0.0009 0.0048 0.006
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0212 0.0212
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Echinococcus multilocularis integrin alpha ps 0.0058 0.072 0.072
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.0249
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0178 0.0178
Echinococcus granulosus lamin 0.0012 0.0085 0.0106
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0011 0.0069 0.0084
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.003 0.0337 0.1594
Loa Loa (eye worm) tubulin gamma chain 0.0352 0.4797 0.6006
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Loa Loa (eye worm) beta-tubulin 0.0583 0.7988 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0466 0.0466
Plasmodium vivax tubulin gamma chain, putative 0.0352 0.4797 0.6003
Echinococcus granulosus histone acetyltransferase KAT2B 0.002 0.0193 0.0241
Mycobacterium tuberculosis Probable lipase LipD 0.003 0.0337 0.1237
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus multilocularis tubulin alpha 3 chain 0.0437 0.5967 0.5967
Trichomonas vaginalis tubulin alpha chain, putative 0.0583 0.7988 1
Onchocerca volvulus 0.003 0.0337 0.1328
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0209 0.0209
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.002 0.0019
Echinococcus granulosus eukaryotic initiation factor 4A 0.0011 0.0069 0.0087
Trichomonas vaginalis tubulin epsilon chain, putative 0.0437 0.5967 0.7467
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0007 0.002 0.001
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0368 0.0458
Brugia malayi secreted modular calcium-binding protein 1 0.0017 0.0152 0.0187
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Trichomonas vaginalis tubulin beta-1 chain, putative 0.015 0.2003 0.2496
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0082 0.0087
Giardia lamblia Histone acetyltransferase GCN5 0.0018 0.017 0.0188
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus granulosus beta tubulin 0.0583 0.7988 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0209 0.0262
Onchocerca volvulus 0.003 0.0337 0.1328
Loa Loa (eye worm) hypothetical protein 0.0033 0.0373 0.0466
Schistosoma mansoni tubulin subunit beta 0.015 0.2003 0.2506
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Mycobacterium ulcerans lipase LipD 0.003 0.0337 0.1594
Entamoeba histolytica acetyltransferase, GNAT family 0.0018 0.017 0.0205
Loa Loa (eye worm) alpha-tubulin 0.0437 0.5967 0.747
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.029 0.0361
Schistosoma mansoni blooms syndrome DNA helicase 0.0006 0.001 0.0009
Trichomonas vaginalis tubulin, putative 0.0174 0.2331 0.2907
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0006 0.001 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0178 0.0223
Brugia malayi acetyltransferase, GNAT family protein 0.0067 0.0845 0.1055
Onchocerca volvulus Glucosylceramidase homolog 0.0078 0.1001 0.4136
Echinococcus granulosus tyrosine protein kinase Blk 0.0018 0.0172 0.0215
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0212 0.0266
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.002 0.0204 0.0249
Brugia malayi Patched related family protein 12 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Leishmania major zeta tubulin, putative 0.0394 0.5383 0.6737
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi MH1 domain containing protein 0.0007 0.0022 0.0025
Leishmania major beta tubulin 0.0583 0.7988 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0127 0.1684 0.2103
Schistosoma mansoni single-minded 0.0021 0.0216 0.0268
Echinococcus granulosus tubulin subunit beta 0.0583 0.7988 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0047 0.0575 0.2169
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.003 0.0337 0.0421
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0011 0.0069 0.0069
Trichomonas vaginalis tubulin beta chain, putative 0.0178 0.2388 0.2978
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) cysteine protease 0.0007 0.0023 0.0028
Brugia malayi Tubulin alpha-2 chain 0.0437 0.5967 0.747
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0154 0.0177
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus multilocularis L aminoadipate semialdehyde 0.0075 0.0955 0.0955
Echinococcus multilocularis fibrillin 2 0.0011 0.0072 0.0072
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Giardia lamblia Alpha-tubulin 0.0437 0.5967 0.7464
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0013 0.0095 0.0118
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Schistosoma mansoni hypothetical protein 0.0021 0.0213 0.0264
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0079 0.101 0.1264
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0259 0.3501 0.4374
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0008 0.0036 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Schistosoma mansoni hypothetical protein 0.0015 0.0124 0.0152
Loa Loa (eye worm) tubulin alpha-3 chain 0.0259 0.3501 0.4383
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0337 0.0406
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Trypanosoma brucei epsilon tubulin 0.0328 0.447 0.5589
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.0965
Schistosoma mansoni hypothetical protein 0.0179 0.2399 0.3001
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0269 0.0269
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0387
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.002 0.001
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Echinococcus multilocularis 0.004 0.048 0.048
Leishmania major beta tubulin 0.0583 0.7988 1
Leishmania major beta tubulin 0.0583 0.7988 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0192 0.2575 1
Mycobacterium ulcerans hypothetical protein 0.001 0.0065 0.0224
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0129 0.1712 0.2141
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0512 0.0638
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0466 0.0466
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0466 0.0581
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0082 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0466 0.0581
Onchocerca volvulus 0.0019 0.0178 0.0658
Toxoplasma gondii thioredoxin reductase 0.0021 0.0208 0.0248
Echinococcus multilocularis fibrillin 1 0.0011 0.0072 0.0072
Echinococcus multilocularis tubulin subunit TubB 0.0437 0.5967 0.5967
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0466 0.0581
Giardia lamblia Tenascin-X 0.0011 0.0072 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0466 0.0581
Trichomonas vaginalis tubulin epsilon chain, putative 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.3775 0.4725
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0437 0.5967 0.7467
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.002 0.0019
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0011 0.0069 0.0191
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0008 0.0028 0.0421
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0212 0.0758
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0209 0.0259
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Brugia malayi SPARC precursor 0.0017 0.0152 0.0187
Echinococcus granulosus expressed conserved protein 0.012 0.1577 0.1975
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0466 0.0581
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0007 0.002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Brugia malayi hypothetical protein 0.0024 0.0259 0.0322
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0139 0.0139
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0466 0.0581
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0045 0.0539 0.0539
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0021 0.0213 0.0213
Loa Loa (eye worm) BEN-1 protein 0.0583 0.7988 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0108 0.0135
Echinococcus multilocularis follistatin 0.0017 0.0152 0.0152
Brugia malayi beta-lactamase family protein 0.003 0.0337 0.0419
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Trichomonas vaginalis glucosylceramidase, putative 0.0082 0.1059 0.1312
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0108 0.0135
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0466 0.0466
Trypanosoma brucei zeta tubulin 0.0394 0.5383 0.6734
Echinococcus granulosus alpha tubulin 0.0437 0.5967 0.747
Schistosoma mansoni integrin beta subunit 0.0299 0.406 0.5082
Giardia lamblia Delta tubulin 0.015 0.2003 0.2489
Echinococcus multilocularis tyrosine protein kinase HCK 0.0015 0.0131 0.0131
Toxoplasma gondii LsmAD domain-containing protein 0.0033 0.0373 0.0455
Brugia malayi Protein kinase domain containing protein 0.0043 0.0522 0.065
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0131
Echinococcus multilocularis insulin receptor 0.0043 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Giardia lamblia Neurogenic locus Notch protein precursor 0.0011 0.0072 0.0065
Loa Loa (eye worm) tubulin beta chain 0.0583 0.7988 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.0028 0.001
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Leishmania major beta tubulin 0.0583 0.7988 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma cruzi target of rapamycin kinase 3 0.0016 0.0138 0.0166
Mycobacterium tuberculosis Probable esterase LipL 0.003 0.0337 0.1237
Echinococcus granulosus neuropeptide receptor A26 0.0206 0.2775 0.3474
Schistosoma mansoni cathepsin F (C01 family) 0.0007 0.0023 0.0026
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0178 0.0223
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0013 0.01 0.0125
Mycobacterium ulcerans putative regulatory protein 0.0016 0.0139 0.0599
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.01 0.0122
Schistosoma mansoni patched 1 0.0055 0.0678 0.0846
Echinococcus multilocularis ubiquitin specific protease 41 0.0032 0.0369 0.0369
Treponema pallidum cell division protein FtsZ 0.015 0.2003 1
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.3124 0.3911
Giardia lamblia Sgs1 DNA helicase, putative 0.0013 0.0095 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi protein C24B5.3 0.0008 0.0028 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.0007 0.0023 0.0021
Schistosoma mansoni tyrosine kinase 0.0132 0.1751 0.219
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0395
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Echinococcus granulosus tubulin delta chain 0.015 0.2003 0.2508
Onchocerca volvulus 0.0019 0.0178 0.0658
Echinococcus granulosus GPCR family 2 0.0014 0.0108 0.0135
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0075 0.0955 0.1193
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0512 0.0638
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0007 0.0022 0.0028
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0108 0.0135
Brugia malayi Fibronectin type III domain containing protein 0.001 0.0065 0.0079
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.001 0.0065 0.0174
Brugia malayi beta-tubulin, identical 0.0583 0.7988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Brugia malayi nuclear receptor RXR 0.0021 0.0209 0.0259
Onchocerca volvulus 0.0011 0.0072 0.0209
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0466 0.0581
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0466 0.0584
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0178 0.0178
Plasmodium vivax acyl-CoA synthetase, putative 0.0008 0.0028 0.0028
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Trichomonas vaginalis glucosylceramidase, putative 0.0082 0.1059 0.1312
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0269 0.1252
Leishmania major gamma-tubulin 0.0352 0.4797 0.6003
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0212 0.0266
Loa Loa (eye worm) DR-78 0.0019 0.0178 0.0223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi hypothetical protein 0.0024 0.0259 0.0322
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0029 0.0321 0.0402
Echinococcus granulosus peroxisome assembly protein 26 0.0437 0.5967 0.747
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0466 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.0208 0.0253
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Trypanosoma brucei tubulin gamma chain 0.0352 0.4797 0.5999
Leishmania major beta tubulin 0.0583 0.7988 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0466 0.1876
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Echinococcus granulosus Niemann Pick C1 protein 0.0127 0.1684 0.2109
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Mycobacterium ulcerans esterase/lipase LipP 0.003 0.0337 0.1594
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0466 0.0584
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Echinococcus granulosus cathepsin l1 0.0007 0.0023 0.0028
Brugia malayi beta-lactamase 0.003 0.0337 0.0419
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0193 0.0239
Loa Loa (eye worm) hypothetical protein 0.0097 0.1269 0.1588
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.011 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0098 0.0107
Toxoplasma gondii hypothetical protein 0.0011 0.0072 0.0078
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0337 0.0419
Schistosoma mansoni tyrosine kinase 0.0072 0.0915 0.1143
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0368 0.0368
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0065 0.0079
Brugia malayi Patched protein homolog 1 0.0008 0.0028 0.0032
Echinococcus granulosus neuropeptide s receptor 0.0206 0.2775 0.3474
Echinococcus granulosus beta LACTamase domain containing family member 0.003 0.0337 0.0421
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0466 0.0584
Schistosoma mansoni tyrosine kinase 0.0021 0.0212 0.0263
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0204 0.0244
Giardia lamblia Tenascin-like 0.0011 0.0072 0.0065
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0062 0.0775 0.0775
Trichomonas vaginalis DNA helicase recq1, putative 0.0018 0.017 0.0198
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0006 0.0009 0.0011
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0212 0.024
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0106
Plasmodium falciparum tubulin epsilon chain, putative 0.0352 0.4792 0.5989
Schistosoma mansoni tubulin subunit gamma 0.0352 0.4797 0.6005
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0032 0.0369 0.046
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0101 0.132 0.1652
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Echinococcus granulosus sterol regulatory element binding protein 0.0055 0.0678 0.0849
Echinococcus granulosus tubulin epsilon chain 0.0352 0.4792 0.6
Echinococcus granulosus tubulin beta 1 chain 0.0583 0.7988 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0466 0.0584
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0011 0.0069 0.0084
Echinococcus granulosus tumor protein p63 0.0148 0.1968 0.2464
Brugia malayi Myosin head containing protein 0.0008 0.0028 0.0032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0108 0.0108
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0466 0.0466
Brugia malayi nuclear receptor NHR-88 0.0019 0.0178 0.022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0029 0.0321 0.0399
Schistosoma mansoni tyrosine kinase 0.0043 0.0522 0.065
Brugia malayi bHLH-PAS transcription factor 0.0016 0.0139 0.0172
Brugia malayi PAS domain containing protein 0.0021 0.0216 0.0268
Loa Loa (eye worm) fibroinase 0.0007 0.0023 0.0028
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) RecQ helicase 0.0018 0.017 0.0213
Loa Loa (eye worm) hypothetical protein 0.0071 0.091 0.1139
Loa Loa (eye worm) MH2 domain-containing protein 0.0007 0.0022 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0008 0.0036 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Loa Loa (eye worm) hypothetical protein 0.0011 0.0069 0.0087
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0072 0.0915 0.1146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0466 0.0584
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0003
Brugia malayi Integrin alpha pat-2 precursor 0.0129 0.1703 0.2129
Brugia malayi MH2 domain containing protein 0.0007 0.0022 0.0025
Echinococcus multilocularis integrin alpha ps 0.0058 0.072 0.072
Echinococcus granulosus tyrosine protein kinase Lyn 0.0022 0.022 0.0275
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0337 0.0419
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0007 0.0022 0.0025
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0007 0.0012 0.0013
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0013 0.0095 0.0118
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0212 0.0258
Schistosoma mansoni cellular tumor antigen P53 0.0022 0.0221 0.0274
Trypanosoma cruzi major cysteine proteinase, putative 0.0022 0.0225 0.0275
Echinococcus granulosus follistatin 0.0017 0.0152 0.019
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0178 0.0658
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Brugia malayi hypothetical protein 0.0032 0.0368 0.0458
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus ubiquitin specific protease 41 0.0032 0.0369 0.0462
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0023 0.0245 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Loa Loa (eye worm) glutathione reductase 0.0021 0.0208 0.026
Brugia malayi latrophilin 2 splice variant baaae 0.0029 0.0325 0.0404
Trypanosoma brucei PAB1-binding protein , putative 0.0033 0.0373 0.0452
Echinococcus multilocularis tyrosine protein kinase Srms 0.0018 0.0172 0.0172
Echinococcus granulosus tubulin alpha 0.0328 0.447 0.5596
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0055 0.0678 0.0849
Loa Loa (eye worm) hypothetical protein 0.0098 0.1275 0.1596
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Brugia malayi nuclear receptor NHR-88 0.0039 0.0466 0.0581
Echinococcus multilocularis tubulin subunit beta 0.0583 0.7988 0.7988
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0007 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0127 0.1684 0.2109
Brugia malayi Isocitrate dehydrogenase 0.002 0.0204 0.0253
Giardia lamblia Neurogenic locus notch-like protein 0.0011 0.0072 0.0065
Echinococcus multilocularis NCK adaptor protein 0.0006 0.0002 0.0002
Brugia malayi hypothetical protein 0.0033 0.0373 0.0464
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Brugia malayi Tubulin gamma chain 0.0352 0.4797 0.6005
Trichomonas vaginalis hypothetical protein 0.0011 0.0072 0.0075
Leishmania major beta tubulin 0.0583 0.7988 1
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0024 0.0259 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0466 0.0584
Entamoeba histolytica protein kinase, putative 0.0015 0.0131 0.0156
Echinococcus multilocularis adam 0.0011 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0021 0.0213 0.0266
Echinococcus multilocularis geminin 0.0219 0.2956 0.2956
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0021 0.0213 0.0213
Brugia malayi hypothetical protein 0.0079 0.101 0.1262
Schistosoma mansoni organic anion transporter 0.0024 0.0259 0.0322
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.0249
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus granulosus adam 0.0011 0.0072 0.009
Schistosoma mansoni smad 0.0007 0.0022 0.0025
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0178 0.0223
Brugia malayi Patched related family protein 10 0.0008 0.0028 0.0032
Brugia malayi hypothetical protein 0.0021 0.0209 0.0259
Trypanosoma brucei epsilon tubulin 0.0352 0.4792 0.5993
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0067 0.0845 0.1055
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0007 0.0023 0.0028
Echinococcus multilocularis cysteine protease 0.0007 0.0023 0.0023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0269 0.0972
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0009 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Echinococcus multilocularis protein patched 0.0055 0.0678 0.0678
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0466 0.0581
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0007 0.0023 0.0003
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0108 0.0133
Echinococcus multilocularis cpg binding protein 0.0013 0.0105 0.0105
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0368 0.0461
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0032 0.0369 0.0456
Trichomonas vaginalis tubulin alpha chain, putative 0.0328 0.447 0.5589
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0007 0.0023 0.0023
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0178 0.0178
Echinococcus multilocularis tyrosine protein kinase Blk 0.0018 0.0172 0.0172
Schistosoma mansoni hypothetical protein 0.0219 0.2956 0.3699
Brugia malayi Papain family cysteine protease containing protein 0.0007 0.0023 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0178 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0104 0.0114
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0178 0.022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Toxoplasma gondii protease inhibitor PI2 0.0017 0.0152 0.0178
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0193 0.0235
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Loa Loa (eye worm) TK protein kinase 0.0015 0.0131 0.0164
Schistosoma mansoni zinc finger protein 0.0019 0.0178 0.022
Trypanosoma cruzi trypanothione reductase, putative 0.0007 0.002 0.0019
Schistosoma mansoni DNA helicase recq5 0.0013 0.0095 0.0116
Echinococcus multilocularis beta tubulin 0.0583 0.7988 0.7988
Loa Loa (eye worm) tubulin alpha 2 0.0286 0.3885 0.4864
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0067 0.0845 0.0845
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Loa Loa (eye worm) integrin beta-2 0.0512 0.7006 0.8772
Brugia malayi eukaryotic initiation factor 4A 0.0011 0.0069 0.0084
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0466 0.0581
Trypanosoma brucei beta tubulin 0.0328 0.447 0.5589
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0369 0.0447
Echinococcus multilocularis epidermal growth factor receptor 0.0132 0.1751 0.1751
Trypanosoma cruzi MFS transporter, putative 0.0024 0.0259 0.0318
Entamoeba histolytica acyl-coA synthetase, putative 0.001 0.0065 0.0073
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0466 0.0581
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Schistosoma mansoni integrin alpha-ps 0.003 0.0337 0.0419
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0047 0.0575 0.2169
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Toxoplasma gondii NADPH-glutathione reductase 0.0007 0.002 0.0014
Onchocerca volvulus 0.0008 0.0028 0.0023
Brugia malayi Tyrosine-protein kinase abl-1 0.0056 0.0693 0.0865
Mycobacterium ulcerans hypothetical protein 0.003 0.0337 0.1594
Echinococcus multilocularis sterol regulatory element binding protein 0.0055 0.0678 0.0678
Loa Loa (eye worm) hypothetical protein 0.0079 0.101 0.1264
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0678 0.0834
Schistosoma mansoni tyrosine kinase 0.0046 0.0552 0.0688
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0369 0.0462
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0369 0.0447
Brugia malayi intermediate filament protein 0.0012 0.0085 0.0103
Leishmania major delta tubulin, putative 0.0296 0.4025 0.5036
Echinococcus multilocularis hypothetical protein 0.0437 0.5967 0.5967
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus multilocularis Immunoglobulin 0.0009 0.0048 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0021 0.0213 0.0266
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.024
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0066 0.0071
Plasmodium falciparum lipid/sterol:H+ symporter 0.0008 0.0028 0.001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.001 0.0065 0.0224
Mycobacterium ulcerans fatty-acid-CoA ligase 0.001 0.0065 0.0224
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0006 0.0002 0.0003
Brugia malayi tubulin alpha chain - mouse 0.0437 0.5967 0.747
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0009 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis tubulin epsilon chain, putative 0.0437 0.5967 0.7467
Trichomonas vaginalis tubulin gamma chain, putative 0.0352 0.4797 0.5999
Entamoeba histolytica hypothetical protein 0.0021 0.0212 0.0258
Brugia malayi Bloom's syndrome protein homolog 0.0018 0.017 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0369 0.0447
Brugia malayi nuclear receptor RXR 0.0019 0.0178 0.022
Echinococcus multilocularis tubulin alpha 0.0328 0.447 0.447
Schistosoma mansoni glutaminase 0.0108 0.1419 0.1774
Giardia lamblia Alpha-tubulin 0.0437 0.5967 0.7464
Entamoeba histolytica cysteine proteinase, putative 0.0007 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0103 0.1354 0.1695
Toxoplasma gondii ABC1 family protein 0.003 0.0337 0.041
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0466 0.0581
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0007 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0129
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Echinococcus granulosus intermediate filament protein 0.0012 0.0085 0.0106
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0052 0.0647 0.3006
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.0965
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0013 0.0095 0.0095
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0212 0.0254
Onchocerca volvulus 0.003 0.0337 0.1328
Giardia lamblia High cysteine protein 0.0011 0.0072 0.0065
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0013 0.0095 0.0093
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Echinococcus granulosus insulin receptor 0.0043 0.0522 0.0653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Mycobacterium tuberculosis Probable lipase LipE 0.003 0.0337 0.1237
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi hypothetical protein 0.012 0.1577 0.1972
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0447
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Echinococcus granulosus cpg binding protein 0.0013 0.0105 0.0132
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0011 0.0069 0.0075
Echinococcus granulosus dnaJ subfamily B 0.0179 0.2399 0.3003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0221 0.0276
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0055 0.0684 0.0856
Echinococcus multilocularis expressed protein 0.0017 0.0152 0.0152
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Brugia malayi Niemann-Pick C1 protein precursor 0.0127 0.1684 0.2107
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0466 0.0581
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0296 0.4025 0.5033
Plasmodium falciparum cysteine proteinase falcipain 3 0.0007 0.0023 0.0003
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0178 0.022
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Schistosoma mansoni cathepsin F (C01 family) 0.0007 0.0023 0.0026
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0915 0.0915
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0007 0.0023 0.0028
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0047 0.0575 0.2169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0139 0.0174
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0212 0.0212
Echinococcus multilocularis bloom syndrome protein 0.0018 0.017 0.017
Brugia malayi hypothetical protein 0.0021 0.0213 0.0263
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0337 0.0415
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Echinococcus granulosus survival motor neuron protein 1 0.0103 0.1354 0.1695
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.008
Echinococcus multilocularis smad 0.0007 0.0022 0.0022
Plasmodium vivax glutathione reductase, putative 0.0021 0.0208 0.0252
Echinococcus granulosus integrin alpha 3 0.0099 0.1287 0.1611
Giardia lamblia High cysteine protein 0.0011 0.0072 0.0065
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0212 0.0266
Leishmania major beta tubulin 0.0583 0.7988 1
Entamoeba histolytica tubulin family protein 0.0583 0.7988 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0007 0.0023 0.0023
Brugia malayi isocitrate dehydrogenase 0.002 0.0204 0.0253
Echinococcus granulosus mothers against decapentaplegic 5 0.0007 0.0022 0.0028
Brugia malayi SRC-1 0.0021 0.0212 0.0263
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.002 0.0193 0.0226
Plasmodium vivax ataxin-2 like protein, putative 0.0033 0.0373 0.0459
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0212 0.0212
Echinococcus multilocularis integrin alpha ps 0.0028 0.0304 0.0304
Plasmodium vivax vivapain-2 0.0007 0.0023 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi Tubulin alpha chain 0.015 0.2003 0.2506
Echinococcus granulosus tubulin subunit TubB 0.0437 0.5967 0.747
Giardia lamblia Epsilon tubulin 0.0174 0.2326 0.2894
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0178 0.022
Trichomonas vaginalis tubulin epsilon chain, putative 0.015 0.2003 0.2496
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0286 0.3885 0.4856
Brugia malayi hypothetical protein 0.0019 0.0178 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0009 0.0048 0.0057
Onchocerca volvulus 0.0024 0.0259 0.0999
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Trypanosoma brucei tubulin delta chain 0.0296 0.4025 0.5031
Echinococcus granulosus integrin alpha ps 0.0028 0.0304 0.0381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma cruzi tubulin gamma chain 0.0352 0.4797 0.6003
Brugia malayi Stress-activated protein kinase jnk-1 0.0278 0.3775 0.4725
Toxoplasma gondii beta-1 tubulin, putative 0.0583 0.7988 1
Schistosoma mansoni agrin 0.0017 0.0152 0.0187
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0174 0.2326 0.2903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Schistosoma mansoni organic anion transporter 0.0024 0.0259 0.0322
Leishmania major epsilon tubulin, putative 0.0352 0.4792 0.5997
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.057 0.0711
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Leishmania major hypothetical protein, conserved 0.0033 0.0373 0.046
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.007 0.008
Echinococcus granulosus Solute carrier organic anion transporter family 0.0024 0.0259 0.0324
Trypanosoma cruzi cruzipain precursor, putative 0.0028 0.0308 0.0379
Loa Loa (eye worm) tubulin alpha-2 chain 0.0437 0.5967 0.747
Echinococcus multilocularis neuropeptide receptor A26 0.0206 0.2775 0.2775
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Loa Loa (eye worm) TK protein kinase 0.0047 0.057 0.0713
Entamoeba histolytica tubulin gamma chain 0.0352 0.4797 0.6003
Plasmodium falciparum tubulin beta chain 0.0583 0.7988 1
Onchocerca volvulus 0.0024 0.0259 0.0999
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0193 0.0242
Echinococcus multilocularis tyrosine protein kinase Abl 0.0043 0.0513 0.0513
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Leishmania major beta tubulin 0.0583 0.7988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Toxoplasma gondii alpha-tubulin I, putative 0.0437 0.5967 0.7467
Leishmania major eukaryotic initiation factor 4a, putative 0.0011 0.0069 0.008
Echinococcus multilocularis tubulin gamma 1 chain 0.0352 0.4797 0.4797
Onchocerca volvulus 0.0075 0.0955 0.3941
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.001 0.0065 0.0224
Onchocerca volvulus 0.0008 0.0028 0.0023
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0193 0.0193
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Trichomonas vaginalis DNA helicase recq, putative 0.0018 0.017 0.0198
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0011 0.0069 0.0087
Echinococcus multilocularis Smad4 0.0007 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Echinococcus multilocularis tubulin alpha 3 chain 0.0437 0.5967 0.5967
Trichomonas vaginalis glutaminase, putative 0.0108 0.1419 0.1764
Schistosoma mansoni thyroid hormone receptor 0.0094 0.1229 0.1536
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis survival motor neuron protein 1 0.0103 0.1354 0.1354
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0032 0.0369 0.0455
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Leishmania major beta tubulin 0.0583 0.7988 1
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Trichomonas vaginalis tubulin, putative 0.0178 0.2388 0.2978
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0021 0.0213 0.0266
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0096 0.1245 0.1245
Brugia malayi CHE-14 protein 0.0055 0.0678 0.0846
Trypanosoma brucei isocitrate dehydrogenase, putative 0.002 0.0204 0.024
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Giardia lamblia Tenascin precursor 0.0011 0.0072 0.0065
Echinococcus multilocularis mothers against decapentaplegic 5 0.0007 0.0022 0.0022
Echinococcus granulosus lamin dm0 0.0012 0.0085 0.0106
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.1405 0.1759
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0466 0.0581
Echinococcus multilocularis musashi 0.0012 0.0085 0.0085
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0337 0.0406
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Echinococcus multilocularis thyroid hormone receptor alpha 0.0094 0.1229 0.1229
Entamoeba histolytica tubulin alpha chain, putative 0.0437 0.5967 0.7469
Treponema pallidum ATP-dependent RNA helicase 0.0011 0.0069 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0006 0.0002 0.0003
Leishmania major phosphatidylinositol 3-kinase, putative 0.0007 0.0012 0.0009
Echinococcus multilocularis neuropeptide s receptor 0.0206 0.2775 0.2775
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus granulosus tubulin alpha 3 chain 0.0437 0.5967 0.747
Echinococcus multilocularis tubulin epsilon chain 0.0352 0.4792 0.4792
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Echinococcus granulosus beta tubulin 0.0583 0.7988 1
Echinococcus granulosus integrin beta 2 0.0378 0.5149 0.6447
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Brugia malayi MH2 domain containing protein 0.0007 0.0022 0.0025
Mycobacterium tuberculosis Probable conserved lipoprotein 0.003 0.0337 0.1237
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.001 0.0065 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0193 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0373 0.0442
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0007 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0037 0.0432 0.0541
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0373 0.046
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni vesicular amine transporter 0.0009 0.0048 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0212 0.0212
Brugia malayi Tubulin alpha-2 chain 0.0437 0.5967 0.747
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0017 0.0155 0.0169
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0047 0.0575 0.263
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0466 0.0581
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Echinococcus multilocularis tubulin beta 1 chain 0.0583 0.7988 0.7988
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0007 0.0023 0.0003
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0011 0.0069 0.0061
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0025 0.0269 0.0334
Loa Loa (eye worm) CXXC zinc finger family protein 0.0013 0.0095 0.0119
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0007 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0075 0.0955 0.1195
Loa Loa (eye worm) hypothetical protein 0.0006 0.001 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0013 0.0095 0.0118
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0011 0.0069 0.0069
Onchocerca volvulus 0.0008 0.0028 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Echinococcus granulosus single minded 2 0.0016 0.0139 0.0174
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Plasmodium vivax RNA helicase-1, putative 0.0011 0.0069 0.0079
Mycobacterium leprae conserved hypothetical protein 0.003 0.0337 0.1402
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0337 0.0415
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0193 0.0235
Echinococcus multilocularis lamin dm0 0.0012 0.0085 0.0085
Echinococcus multilocularis lamin 0.0012 0.0085 0.0085
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0007 0.0012 0.0016
Echinococcus multilocularis protein dispatched 1 0.0062 0.0785 0.0785
Leishmania major eukaryotic initiation factor 4a, putative 0.0011 0.0069 0.008
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0032 0.0369 0.046
Onchocerca volvulus 0.0024 0.0259 0.0999
Onchocerca volvulus 0.0022 0.0221 0.0838
Loa Loa (eye worm) hypoxia-induced factor 1 0.0066 0.0833 0.1043
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Treponema pallidum NADH oxidase 0.0007 0.002 0.0055
Onchocerca volvulus 0.0012 0.0085 0.0262
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0007 0.002 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0052 0.0647 0.2455
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0108 0.0133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0116
Echinococcus multilocularis transfer RNA-Lys 0.0016 0.0139 0.0139
Brugia malayi Integrin beta pat-3 precursor 0.0512 0.7006 0.8771
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0212 0.0266
Echinococcus granulosus bloom syndrome protein 0.0018 0.017 0.0213
Schistosoma mansoni intermediate filament proteins 0.0012 0.0085 0.0103
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Schistosoma mansoni hypothetical protein 0.0219 0.2956 0.3699
Schistosoma mansoni thyroid hormone receptor 0.0094 0.1229 0.1536
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0029 0.0321 0.0395
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Schistosoma mansoni lamin 0.0012 0.0085 0.0103
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0456
Schistosoma mansoni hypothetical protein 0.0055 0.0684 0.0854
Plasmodium vivax hypothetical protein, conserved 0.003 0.0337 0.0414
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0178 0.2388 0.2978
Brugia malayi Tubulin beta chain 0.0178 0.2388 0.2987
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0466 0.0584
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0466 0.1876
Schistosoma mansoni tyrosine kinase 0.0043 0.0522 0.065
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0178 0.022
Echinococcus granulosus twitchin 0.0011 0.0074 0.0092
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0286 0.3885 0.4864
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0193 0.0227
Onchocerca volvulus 0.0012 0.0085 0.0262
Trichomonas vaginalis tubulin gamma chain, putative 0.0583 0.7988 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.002 0.0204 0.0256
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0032 0.0369 0.046
Echinococcus granulosus tubulin alpha 3 chain 0.0437 0.5967 0.747
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0395
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0046 0.0552 0.0552
Plasmodium falciparum eukaryotic initiation factor 4A 0.0011 0.0069 0.0061
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0583 0.7988 0.7988
Loa Loa (eye worm) tubulin beta-1 chain 0.0583 0.7988 1
Schistosoma mansoni DNA helicase recq1 0.0013 0.0095 0.0116
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0209 0.0259
Toxoplasma gondii beta-tubulin, putative 0.0583 0.7988 1
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0337 0.0406
Brugia malayi CXXC zinc finger family protein 0.0013 0.0095 0.0116
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.003 0.0337 0.1237
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Echinococcus granulosus smad 0.0007 0.0022 0.0028
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0029 0.0321 0.0399
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0013 0.0095 0.0118
Plasmodium vivax delta tubulin, putative 0.015 0.2003 0.2502
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Entamoeba histolytica acyl-CoA synthetase, putative 0.001 0.0065 0.0073
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0178 0.0223
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Toxoplasma gondii beta tubulin 0.0583 0.7988 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0018 0.017 0.0188
Brugia malayi nuclear hormone receptor 0.0039 0.0466 0.0581
Brugia malayi hypothetical protein 0.0019 0.0178 0.022
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0011 0.0072 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.003 0.0337 0.0337
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.1014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Echinococcus granulosus thioredoxin glutathione reductase 0.0021 0.0208 0.026
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0456
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0116
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0466 0.0584
Loa Loa (eye worm) agrin synaptic family protein 0.0017 0.0152 0.019
Echinococcus multilocularis integrin alpha 3 0.0099 0.1287 0.1287
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0007 0.002 0.0026
Loa Loa (eye worm) acetyltransferase 0.0067 0.0845 0.1057
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0178 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Schistosoma mansoni tyrosine kinase 0.0072 0.0915 0.1143
Trypanosoma brucei trypanothione reductase 0.0021 0.0208 0.0245
Plasmodium vivax patched family protein, putative 0.0008 0.0028 0.0027
Schistosoma mansoni nuclear receptor 0.0019 0.0178 0.022
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0466 0.0584
Schistosoma mansoni tyrosine kinase 0.0008 0.0036 0.0042
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0097 0.1269 0.1586
Toxoplasma gondii target of rapamycin (TOR), putative 0.0015 0.0124 0.0143
Loa Loa (eye worm) tubulin alpha chain 0.0437 0.5967 0.747
Schistosoma mansoni tyrosine kinase 0.0021 0.0212 0.0263
Brugia malayi tailless protein 0.0019 0.0178 0.022
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.003 0.0337 0.0419
Toxoplasma gondii hypothetical protein 0.0008 0.0028 0.0023
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0008 0.0034 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Giardia lamblia Gamma tubulin 0.0352 0.4797 0.5995
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0466 0.0581
Echinococcus granulosus histone acetyltransferase KAT2B 0.0065 0.0819 0.1025
Trichomonas vaginalis tubulin gamma chain, putative 0.0352 0.4792 0.5993
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus granulosus integrin alpha ps 0.0058 0.072 0.0901
Echinococcus granulosus roundabout 2 0.0013 0.0102 0.0127
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0212 0.0212
Loa Loa (eye worm) phosphatidylinositol 3 0.0007 0.0012 0.0016
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0178 0.022
Brugia malayi nuclear receptor NHR-67 0.0019 0.0178 0.022
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0212 0.0259
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0124 0.0124
Echinococcus multilocularis transcription factor Dp 1 0.0017 0.0153 0.0153
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.1063 0.1329
Loa Loa (eye worm) hypothetical protein 0.0014 0.0108 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Brugia malayi Tyrosine-protein kinase abl-1 0.0043 0.0513 0.064
Plasmodium vivax tubulin epsilon chain, putative 0.0352 0.4792 0.5996
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0466 0.0466
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0256
Echinococcus granulosus c src tyrosine kinase 0.0008 0.0036 0.0044
Echinococcus multilocularis Niemann Pick C1 protein 0.0182 0.2441 0.2441
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0278 0.3775 0.4726
Plasmodium vivax thioredoxin reductase, putative 0.0021 0.0208 0.0252
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Echinococcus granulosus agrin 0.0017 0.0152 0.019
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0212 0.0749
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Loa Loa (eye worm) glutaminase 2 0.0108 0.1419 0.1777
Loa Loa (eye worm) hypothetical protein 0.0437 0.5967 0.747
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Echinococcus granulosus tyrosine protein kinase HCK 0.0015 0.0131 0.0164
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Onchocerca volvulus 0.012 0.1577 0.6574
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0178 0.022
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0007 0.002 0.0023
Trichomonas vaginalis tubulin gamma chain, putative 0.015 0.2003 0.2496
Onchocerca volvulus 0.0039 0.0466 0.1876
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0178 0.0178
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Echinococcus multilocularis cathepsin L cysteine protease 0.0007 0.0023 0.0023
Echinococcus multilocularis neuroglian 0.001 0.0066 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Echinococcus granulosus NCK adaptor protein 0.0006 0.0002 0.0003
Brugia malayi Patched related family protein 4 0.0008 0.0028 0.0032
Brugia malayi prostaglandin transporter 0.0024 0.0259 0.0322
Echinococcus granulosus tubulin gamma 1 chain 0.0352 0.4797 0.6006
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0007 0.0022 0.0022
Onchocerca volvulus Protein patched homolog 0.0008 0.0028 0.0023
Mycobacterium ulcerans glutaminase 0.0108 0.1419 0.7054
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0466 0.0466
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Echinococcus granulosus tyrosine kinase 0.0018 0.0172 0.0215
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0466 0.1876
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0021 0.0212 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0466 0.0581
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0193 0.0235
Brugia malayi steroid hormone receptor 0.0039 0.0466 0.0581
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0018 0.0172 0.0172
Trichomonas vaginalis tubulin epsilon chain, putative 0.0583 0.7988 1
Leishmania major beta tubulin 0.0583 0.7988 1
Plasmodium falciparum alpha tubulin 2 0.0437 0.5967 0.7464
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0422
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Trichomonas vaginalis glutathione reductase, putative 0.0007 0.002 0.001
Brugia malayi ecdysteroid receptor 0.0039 0.0466 0.0581
Brugia malayi hypoxia-induced factor 1 0.0066 0.0833 0.1041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis mercuric reductase, putative 0.0007 0.002 0.001
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0178 0.0223
Loa Loa (eye worm) TK/INSR protein kinase 0.0043 0.0522 0.0653
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0006 0.001 0.0005
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0119 0.1567 0.1959
Echinococcus granulosus cathepsin L cysteine proteinase 0.0007 0.0023 0.0028
Loa Loa (eye worm) BEN-1 protein 0.0583 0.7988 1
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0915 0.1146
Brugia malayi ecdysone receptor 0.0019 0.0178 0.022
Echinococcus multilocularis protein jagged 2 0.0011 0.0072 0.0072
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0082 0.0102
Loa Loa (eye worm) tubulin alpha chain 0.0437 0.5967 0.747
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0466 0.0584
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0096 0.1245 0.1559
Echinococcus granulosus epidermal growth factor receptor 0.0132 0.1751 0.2192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.003 0.0337 0.1237
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0466 0.0466
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0046 0.0552 0.0691
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0193 0.0235
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0029 0.0321 0.0321
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0025 0.0274 0.0337
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0046 0.0552 0.0552
Echinococcus multilocularis thioredoxin glutathione reductase 0.0021 0.0208 0.0208
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus multilocularis tubulin alpha 1C chain 0.0437 0.5967 0.5967
Trypanosoma brucei zeta tubulin, putative 0.0394 0.5383 0.6734
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Echinococcus multilocularis c src tyrosine kinase 0.0008 0.0036 0.0036
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Leishmania major cysteine peptidase A (CPA) 0.0007 0.0023 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0085 0.0106
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0055 0.0678 0.0849
Leishmania major beta tubulin 0.0583 0.7988 1
Echinococcus multilocularis tubulin delta chain 0.015 0.2003 0.2003
Onchocerca volvulus 0.0021 0.0213 0.0807
Mycobacterium tuberculosis Cell division protein FtsZ 0.015 0.2003 0.7762
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus granulosus neuroglian 0.001 0.0066 0.0083
Plasmodium vivax histone acetyltransferase GCN5, putative 0.002 0.0193 0.0234
Loa Loa (eye worm) hypothetical protein 0.0032 0.0369 0.0462
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.3124 0.3124
Brugia malayi MH2 domain containing protein 0.0107 0.1405 0.1757
Trichomonas vaginalis tubulin, putative 0.0583 0.7988 1
Schistosoma mansoni survival motor neuron protein 0.0021 0.0213 0.0264
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Onchocerca volvulus Protein patched homolog 0.0008 0.0028 0.0023
Schistosoma mansoni integrin alpha 0.0129 0.1703 0.2129
Entamoeba histolytica acyl-CoA synthetase, putative 0.001 0.0065 0.0073
Echinococcus granulosus Protein patched homolog 1 0.0055 0.0678 0.0849
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0512 0.0641
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0106
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0178 0.0658
Plasmodium vivax tubulin alpha chain, putative 0.0437 0.5967 0.7469
Trichomonas vaginalis conserved hypothetical protein 0.015 0.2003 0.2496
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0466 0.0581
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0045 0.0539 0.0675
Echinococcus granulosus fibrillin 1 0.0011 0.0072 0.009
Echinococcus granulosus transcription factor Dp 1 0.0017 0.0153 0.0191
Trypanosoma brucei epsilon tubulin 0.0352 0.4792 0.5993
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0466 0.0584
Echinococcus multilocularis expressed conserved protein 0.012 0.1577 0.1577
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0018 0.0172 0.0215
Echinococcus granulosus fibroblast growth factor receptor 4 0.0046 0.0552 0.0691
Brugia malayi cytoplasmic intermediate filament protein 0.0006 0.0009 0.0008
Leishmania major hypothetical protein, conserved 0.003 0.0337 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0466 0.0581
Schistosoma mansoni coup transcription factor 0.0039 0.0466 0.0581
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0269 0.1252
Brugia malayi conserved hypotetical protein 0.0019 0.0178 0.022
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0466 0.0584
Entamoeba histolytica recQ family helicase, putative 0.0014 0.011 0.013
Onchocerca volvulus 0.0016 0.0139 0.0493
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0007 0.0012 0.0013
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0016 0.0138 0.0157
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Echinococcus granulosus fibrillin 2 0.0011 0.0072 0.009
Echinococcus multilocularis growth factor receptor bound protein 2 0.0006 0.0002 0.0002
Brugia malayi Thioredoxin reductase 0.0021 0.0208 0.0257
Plasmodium falciparum alpha tubulin 1 0.0437 0.5967 0.7464
Brugia malayi Tubulin beta-1 chain 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Schistosoma mansoni hypothetical protein 0.0028 0.0304 0.0378
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.001 0.0066 0.0083
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi hypothetical protein 0.0098 0.1275 0.1593
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0466 0.0581
Echinococcus multilocularis cathepsin L cysteine protease 0.0007 0.0023 0.0023
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0178 0.022
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.002 0.0204 0.0231
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0028 0.0304 0.0381
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0178 0.0223
Onchocerca volvulus 0.0017 0.0152 0.0546
Loa Loa (eye worm) SRC-1 0.0021 0.0212 0.0266
Loa Loa (eye worm) hypothetical protein 0.0012 0.0085 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Leishmania major trypanothione reductase 0.0021 0.0208 0.0253
Toxoplasma gondii histone lysine methyltransferase SET1 0.0025 0.0273 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.015 0.2003 0.2496
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0269 0.033
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0373 0.0442
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0178 0.0223
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Mycobacterium tuberculosis Probable hydrolase 0.003 0.0337 0.1237
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0328 0.447 0.5591
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.002 0.0204 0.0253
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0466 0.0581
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) beta-lactamase 0.003 0.0337 0.0421
Loa Loa (eye worm) TK/ABL protein kinase 0.0096 0.1245 0.1559
Echinococcus multilocularis roundabout 2 0.0013 0.0102 0.0102
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Echinococcus multilocularis cysteine protease 0.0007 0.0023 0.0023
Trypanosoma cruzi epsilon tubulin, putative 0.0352 0.4792 0.5997
Echinococcus granulosus TGF beta signal transducer SmadC 0.0007 0.0022 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Echinococcus multilocularis peroxisome assembly protein 26 0.0437 0.5967 0.5967

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 5.78 Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP ChEMBL. 23416008
Kd (binding) = 1.66 uM Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP ChEMBL. 23416008
Kd (binding) = 1.66 uM Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysis ChEMBL. 23498914

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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