Detailed information for compound 1730726

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.493 | Formula: C26H23N5O2
  • H donors: 2 H acceptors: 4 LogP: 4.99 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)nc(n2c1ccnc(n1)NC1CCOCC1)c1ccc2c(c1)cccc2
  • InChi: 1S/C26H23N5O2/c32-21-7-8-23-22(16-21)29-25(19-6-5-17-3-1-2-4-18(17)15-19)31(23)24-9-12-27-26(30-24)28-20-10-13-33-14-11-20/h1-9,12,15-16,20,32H,10-11,13-14H2,(H,27,28,30)
  • InChiKey: XOZSAGRTIVKDDL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens mitogen-activated protein kinase 10 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04440 c-Jun N-terminal kinase, putative Get druggable targets OG5_129677 All targets in OG5_129677
Echinococcus multilocularis c Jun NH2 terminal kinase Get druggable targets OG5_129677 All targets in OG5_129677
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
Schistosoma japonicum IPR000164,Histone H3;IPR009072,Histone-fold,domain-containing Get druggable targets OG5_129677 All targets in OG5_129677
Brugia malayi Stress-activated protein kinase jnk-1 Get druggable targets OG5_129677 All targets in OG5_129677
Echinococcus granulosus c-Jun N-terminal kinases Get druggable targets OG5_129677 All targets in OG5_129677
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase Get druggable targets OG5_129677 All targets in OG5_129677
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi ecdysteroid receptor 0.0039 0.0466 0.0581
Echinococcus granulosus Niemann Pick C1 protein 0.0182 0.2441 0.3056
Loa Loa (eye worm) SRC-1 0.0021 0.0212 0.0266
Trypanosoma cruzi epsilon tubulin, putative 0.0352 0.4792 0.5997
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0286 0.3885 0.4864
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Brugia malayi nuclear hormone receptor 0.0039 0.0466 0.0581
Trichomonas vaginalis tubulin alpha chain, putative 0.0583 0.7988 1
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus beta tubulin 0.0583 0.7988 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0256
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0047 0.0575 0.263
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0369 0.0447
Giardia lamblia Alpha-tubulin 0.0437 0.5967 0.7464
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0337 0.0415
Echinococcus granulosus tyrosine protein kinase Lyn 0.0022 0.022 0.0275
Brugia malayi hypothetical protein 0.0019 0.0178 0.022
Leishmania major beta tubulin 0.0583 0.7988 1
Trypanosoma cruzi tubulin delta chain 0.0296 0.4025 0.5036
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0024 0.0259 0.0324
Loa Loa (eye worm) glutaminase 2 0.0108 0.1419 0.1777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Brugia malayi protein C24B5.3 0.0008 0.0028 0.0032
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0178 0.022
Brugia malayi MH1 domain containing protein 0.0007 0.0022 0.0025
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0466 0.0581
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0466 0.0466
Onchocerca volvulus Glucosylceramidase homolog 0.0078 0.1001 0.4136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Trypanosoma brucei zeta tubulin 0.0394 0.5383 0.6734
Onchocerca volvulus 0.0008 0.0028 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Echinococcus granulosus tyrosine protein kinase Blk 0.0018 0.0172 0.0215
Loa Loa (eye worm) CXXC zinc finger family protein 0.0013 0.0095 0.0119
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.002 0.0193 0.0226
Schistosoma mansoni hypothetical protein 0.0055 0.0684 0.0854
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0466 0.0581
Giardia lamblia High cysteine protein 0.0011 0.0072 0.0065
Trichomonas vaginalis glutaminase, putative 0.0108 0.1419 0.1764
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0129
Brugia malayi hypothetical protein 0.012 0.1577 0.1972
Loa Loa (eye worm) hypothetical protein 0.0075 0.0955 0.1195
Leishmania major epsilon tubulin, putative 0.0352 0.4792 0.5997
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Brugia malayi Tubulin alpha-2 chain 0.0437 0.5967 0.747
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0466 0.0466
Schistosoma mansoni tyrosine kinase 0.0008 0.0036 0.0042
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0131
Onchocerca volvulus 0.0012 0.0085 0.0262
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0107
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Echinococcus multilocularis dnaJ subfamily B 0.0179 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0437 0.5967 0.747
Loa Loa (eye worm) alpha-tubulin 0.0437 0.5967 0.747
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0007 0.0022 0.0025
Trichomonas vaginalis tubulin gamma chain, putative 0.015 0.2003 0.2496
Echinococcus multilocularis mothers against decapentaplegic 5 0.0007 0.0022 0.0022
Brugia malayi tailless protein 0.0019 0.0178 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0008 0.0028 0.0032
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0047 0.0575 0.2169
Loa Loa (eye worm) hypothetical protein 0.0014 0.0108 0.0135
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0178 0.022
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0062 0.0775 0.0775
Giardia lamblia Neurogenic locus notch-like protein 0.0011 0.0072 0.0065
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.1063 0.1329
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni hypothetical protein 0.0219 0.2956 0.3699
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0193 0.0227
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Brugia malayi Isocitrate dehydrogenase 0.002 0.0204 0.0253
Brugia malayi nuclear receptor NHR-88 0.0019 0.0178 0.022
Onchocerca volvulus 0.0019 0.0178 0.0658
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0108 0.0135
Brugia malayi Integrin alpha pat-2 precursor 0.0129 0.1703 0.2129
Toxoplasma gondii hypothetical protein 0.0011 0.0072 0.0078
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.0071
Brugia malayi hypothetical protein 0.0103 0.1354 0.1692
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0007 0.0023 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus granulosus agrin 0.0017 0.0152 0.019
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0052 0.0647 0.2455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Brugia malayi Tubulin gamma chain 0.0352 0.4797 0.6005
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0007 0.002 0.0026
Toxoplasma gondii histone lysine methyltransferase SET1 0.0025 0.0273 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0678 0.0834
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0466 0.0581
Onchocerca volvulus 0.0178 0.2388 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0512 0.0638
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0466 0.0466
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.008
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0011 0.0069 0.0069
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0016 0.0138 0.0166
Schistosoma mansoni tubulin subunit epsilon 0.0352 0.4792 0.5998
Schistosoma mansoni cell adhesion molecule 0.0012 0.0084 0.0102
Brugia malayi SRC-1 0.0021 0.0212 0.0263
Plasmodium falciparum alpha tubulin 1 0.0437 0.5967 0.7464
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Brugia malayi ecdysone receptor 0.0019 0.0178 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Onchocerca volvulus 0.0011 0.0072 0.0209
Brugia malayi Patched related family protein 12 0.0008 0.0028 0.0032
Schistosoma mansoni single-minded 0.0021 0.0216 0.0268
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Brugia malayi bHLH-PAS transcription factor 0.0016 0.0139 0.0172
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Echinococcus multilocularis bloom syndrome protein 0.0018 0.017 0.017
Trypanosoma cruzi epsilon tubulin, putative 0.0352 0.4792 0.5997
Echinococcus multilocularis thioredoxin glutathione reductase 0.0021 0.0208 0.0208
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0045 0.0539 0.0539
Toxoplasma gondii hypothetical protein 0.0008 0.0028 0.0023
Loa Loa (eye worm) isocitrate dehydrogenase 0.002 0.0204 0.0256
Echinococcus multilocularis tubulin alpha 1C chain 0.0437 0.5967 0.5967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Leishmania major beta tubulin 0.0583 0.7988 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0018 0.017 0.0188
Onchocerca volvulus 0.0016 0.0139 0.0493
Trypanosoma brucei tubulin gamma chain 0.0352 0.4797 0.5999
Trichomonas vaginalis tubulin beta chain, putative 0.0583 0.7988 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0116
Mycobacterium ulcerans lipase LipD 0.003 0.0337 0.1594
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0178 0.0223
Brugia malayi protein C24B5.3 0.0008 0.0028 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0007 0.002 0.0023
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0278 0.3775 0.3775
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0021 0.0213 0.0264
Echinococcus granulosus cpg binding protein 0.0013 0.0105 0.0132
Brugia malayi MH2 domain containing protein 0.0007 0.0022 0.0025
Echinococcus granulosus tubulin subunit beta 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Trypanosoma cruzi alpha tubulin, putative 0.0437 0.5967 0.7469
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0127 0.1684 0.2103
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0046 0.0552 0.0691
Echinococcus multilocularis GPCR, family 2 0.0014 0.0108 0.0108
Entamoeba histolytica tubulin family protein 0.0583 0.7988 1
Plasmodium vivax vivapain-2 0.0007 0.0023 0.0021
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0029 0.0321 0.0395
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0029 0.0321 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Echinococcus granulosus cathepsin l cysteine peptidase 0.0007 0.0023 0.0028
Schistosoma mansoni intermediate filament proteins 0.0012 0.0085 0.0103
Giardia lamblia Tenascin-X 0.0011 0.0072 0.0065
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Trypanosoma brucei beta tubulin 0.0328 0.447 0.5589
Treponema pallidum ATP-dependent RNA helicase 0.0011 0.0069 0.03
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi hypothetical protein 0.0079 0.101 0.1262
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0466 0.0584
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0422
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Trichomonas vaginalis glutathione reductase, putative 0.0007 0.002 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Onchocerca volvulus 0.0075 0.0955 0.3941
Echinococcus granulosus dnaJ subfamily B 0.0179 0.2399 0.3003
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0007 0.0023 0.0023
Loa Loa (eye worm) integrin alpha pat-2 0.0198 0.2667 0.3339
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Echinococcus granulosus integrin alpha ps 0.0058 0.072 0.0901
Leishmania major beta tubulin 0.0583 0.7988 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0006 0.0002 0.0002
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0025 0.0269 0.0334
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0047 0.0575 0.2169
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0139 0.0139
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0013 0.0095 0.0095
Plasmodium vivax hypothetical protein, conserved 0.003 0.0337 0.0414
Schistosoma mansoni cathepsin F (C01 family) 0.0007 0.0023 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0466 0.0581
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0466 0.0584
Echinococcus multilocularis sterol regulatory element binding protein 0.0055 0.0678 0.0678
Plasmodium falciparum thioredoxin reductase 0.0021 0.0208 0.0235
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0193 0.0193
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Trichomonas vaginalis tubulin beta-1 chain, putative 0.015 0.2003 0.2496
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0007 0.0012 0.0012
Loa Loa (eye worm) tubulin beta chain 0.0583 0.7988 1
Schistosoma mansoni integrin alpha-ps 0.0058 0.072 0.0899
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0024 0.0259 0.0324
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0212 0.0758
Echinococcus granulosus c-Jun N-terminal kinases 0.0278 0.3775 0.4726
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0046 0.0552 0.0552
Loa Loa (eye worm) thioredoxin reductase 0.0021 0.0208 0.026
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0178 0.022
Leishmania major beta tubulin 0.0583 0.7988 1
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Schistosoma mansoni hypothetical protein 0.0015 0.0124 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0008 0.0036 0.0042
Toxoplasma gondii target of rapamycin (TOR), putative 0.0015 0.0124 0.0143
Schistosoma mansoni follistatin 0.0017 0.0152 0.0187
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0007 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Plasmodium vivax tubulin alpha chain, putative 0.0437 0.5967 0.7469
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0466 0.0584
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0296 0.4025 0.5033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0178 0.0178
Brugia malayi protein-tyrosine kinase 0.0018 0.0172 0.0213
Loa Loa (eye worm) hypothetical protein 0.0022 0.0221 0.0276
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Loa Loa (eye worm) hypothetical protein 0.0032 0.0369 0.0462
Brugia malayi MH2 domain containing protein 0.0107 0.1405 0.1757
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus geminin 0.0219 0.2956 0.3701
Loa Loa (eye worm) tubulin beta chain 0.015 0.2003 0.2508
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0011 0.0069 0.008
Echinococcus granulosus neuropeptide s receptor 0.0206 0.2775 0.3474
Loa Loa (eye worm) hypothetical protein 0.0011 0.0069 0.0087
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0466 0.0466
Echinococcus granulosus tubulin gamma 1 chain 0.0352 0.4797 0.6006
Schistosoma mansoni nuclear receptor 0.0019 0.0178 0.022
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0021 0.0213 0.0266
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0007 0.002 0.0019
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0024 0.0259 0.0259
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0006 0.0002 0.0003
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Brugia malayi Tyrosine-protein kinase abl-1 0.0056 0.0693 0.0865
Brugia malayi Stress-activated protein kinase jnk-1 0.0278 0.3775 0.4725
Echinococcus granulosus GPCR family 2 0.0014 0.0108 0.0135
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0466 0.0581
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.002 0.0204 0.0249
Brugia malayi Tyrosine-protein kinase abl-1 0.0043 0.0513 0.064
Schistosoma mansoni tyrosine kinase 0.0021 0.0212 0.0263
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0178 0.022
Brugia malayi hypothetical protein 0.0033 0.0373 0.0464
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.0249
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0046 0.0552 0.0552
Echinococcus granulosus tubulin subunit TubB 0.0437 0.5967 0.747
Echinococcus multilocularis fibrillin 2 0.0011 0.0072 0.0072
Schistosoma mansoni tyrosine kinase 0.0132 0.1751 0.219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi Smad1 0.0007 0.0022 0.0025
Brugia malayi Patched related family protein 4 0.0008 0.0028 0.0032
Onchocerca volvulus 0.0024 0.0259 0.0999
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0013 0.0095 0.0118
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0466 0.0581
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0269 0.0336
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0016 0.0138 0.0157
Brugia malayi beta-lactamase family protein 0.003 0.0337 0.0419
Loa Loa (eye worm) hypothetical protein 0.0029 0.0325 0.0407
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0097 0.1269 0.1586
Schistosoma mansoni hypothetical protein 0.0028 0.0304 0.0378
Toxoplasma gondii thioredoxin reductase 0.0021 0.0208 0.0248
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.015 0.2003 1
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0209 0.0259
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0007 0.0012 0.0016
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Entamoeba histolytica acyl-CoA synthetase, putative 0.001 0.0065 0.0073
Leishmania major beta tubulin 0.0583 0.7988 1
Giardia lamblia Delta tubulin 0.015 0.2003 0.2489
Echinococcus granulosus tyrosine kinase 0.0018 0.0172 0.0215
Plasmodium falciparum glutathione reductase 0.0021 0.0208 0.0235
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi nuclear receptor RXR 0.0019 0.0178 0.022
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0067 0.0845 0.1055
Brugia malayi Kelch motif family protein 0.0079 0.101 0.1262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0369 0.0447
Echinococcus multilocularis NCK adaptor protein 0.0006 0.0002 0.0002
Onchocerca volvulus 0.0024 0.0259 0.0999
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0373 0.046
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0007 0.0012 0.0013
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Plasmodium vivax patched family protein, putative 0.0008 0.0028 0.0027
Trypanosoma cruzi beta tubulin, putative 0.0583 0.7988 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0178 0.022
Schistosoma mansoni DNA helicase recq1 0.0013 0.0095 0.0116
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Brugia malayi hypothetical protein 0.0024 0.0259 0.0322
Schistosoma mansoni integrin alpha 0.0129 0.1703 0.2129
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0154 0.0177
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Plasmodium vivax RNA helicase-1, putative 0.0011 0.0069 0.0079
Brugia malayi beta-lactamase 0.003 0.0337 0.0419
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0021 0.0213 0.0213
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0259 0.3501 0.4374
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Onchocerca volvulus 0.003 0.0337 0.1328
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0466 0.1876
Echinococcus granulosus expressed conserved protein 0.012 0.1577 0.1975
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0029 0.0321 0.0321
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Trichomonas vaginalis tubulin epsilon chain, putative 0.0437 0.5967 0.7467
Echinococcus multilocularis tubulin gamma 1 chain 0.0352 0.4797 0.4797
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0178 0.0223
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0337 0.0415
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.002 0.0019
Mycobacterium tuberculosis Probable lipase LipE 0.003 0.0337 0.1237
Plasmodium vivax tubulin epsilon chain, putative 0.0352 0.4792 0.5996
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0007 0.0022 0.0028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0368 0.0461
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0007 0.0023 0.0028
Schistosoma mansoni hypothetical protein 0.0219 0.2956 0.3699
Entamoeba histolytica cysteine proteinase, putative 0.0007 0.0023 0.0021
Brugia malayi MH1 domain containing protein 0.0007 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Schistosoma mansoni tyrosine kinase 0.0021 0.0212 0.0263
Mycobacterium leprae Probable lipase LipE 0.003 0.0337 0.1402
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0006 0.0002 0.0003
Brugia malayi Thioredoxin reductase 0.0021 0.0208 0.0257
Echinococcus multilocularis lamin 0.0012 0.0085 0.0085
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0466 0.0581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0466 0.0581
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0013 0.0095 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Echinococcus multilocularis Immunoglobulin 0.0009 0.0048 0.0048
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0178 0.022
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Brugia malayi hypothetical protein 0.0032 0.0368 0.0458
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0055 0.0678 0.0849
Brugia malayi hypothetical protein 0.0098 0.1275 0.1593
Echinococcus granulosus Smad4 0.0007 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi PAS domain containing protein 0.0021 0.0216 0.0268
Echinococcus multilocularis tubulin beta 1 chain 0.0583 0.7988 0.7988
Brugia malayi Patched protein homolog 1 0.0008 0.0028 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0466 0.0584
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0075 0.0955 0.1193
Echinococcus granulosus beta LACTamase domain containing family member 0.003 0.0337 0.0421
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.0208 0.0253
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0466 0.0581
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0178 0.0223
Plasmodium falciparum tubulin beta chain 0.0583 0.7988 1
Echinococcus multilocularis tubulin epsilon chain 0.0352 0.4792 0.4792
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0369 0.0462
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.001 0.0065 0.0224
Trypanosoma cruzi cruzipain precursor, putative 0.0028 0.0308 0.0379
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Echinococcus granulosus alpha tubulin 0.0437 0.5967 0.747
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0456
Echinococcus granulosus Protein patched homolog 1 0.0055 0.0678 0.0849
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.003 0.0337 0.0419
Brugia malayi intermediate filament protein 0.0012 0.0085 0.0103
Schistosoma mansoni lamin 0.0012 0.0085 0.0103
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0018 0.0172 0.0215
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0007 0.002 0.0018
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0021 0.0213 0.0266
Trichomonas vaginalis mercuric reductase, putative 0.0007 0.002 0.001
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0466 0.0581
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus granulosus beta tubulin 0.0583 0.7988 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.003 0.0337 0.1594
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0178 0.022
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0007 0.002 0.0018
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.0965
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0212 0.0266
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0067 0.0845 0.0845
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0178 0.0223
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0212 0.0212
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0032 0.0369 0.046
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0108 0.0133
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis protein patched 0.0055 0.0678 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma brucei zeta tubulin, putative 0.0394 0.5383 0.6734
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0193 0.0242
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Echinococcus granulosus sterol regulatory element binding protein 0.0055 0.0678 0.0849
Echinococcus granulosus follistatin 0.0017 0.0152 0.019
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.001 0.0065 0.0224
Brugia malayi Tubulin beta-1 chain 0.0583 0.7988 1
Leishmania major beta tubulin 0.0583 0.7988 1
Echinococcus multilocularis hypothetical protein 0.0437 0.5967 0.5967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus granulosus histone acetyltransferase KAT2B 0.0065 0.0819 0.1025
Schistosoma mansoni tubulin subunit alpha 0.015 0.2003 0.2506
Echinococcus granulosus tyrosine protein kinase HCK 0.0015 0.0131 0.0164
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0466 0.0584
Echinococcus granulosus tubulin beta 1 chain 0.0583 0.7988 1
Echinococcus granulosus lamin dm0 0.0012 0.0085 0.0106
Echinococcus multilocularis tubulin alpha 3 chain 0.0437 0.5967 0.5967
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0021 0.0213 0.0263
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.001 0.0066 0.0083
Loa Loa (eye worm) hypothetical protein 0.0071 0.091 0.1139
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0006 0.0009 0.0011
Loa Loa (eye worm) cysteine protease 0.0007 0.0023 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Giardia lamblia GTOR 0.002 0.0193 0.0217
Schistosoma mansoni vesicular amine transporter 0.0009 0.0048 0.0057
Trichomonas vaginalis DNA helicase recq, putative 0.0018 0.017 0.0198
Trypanosoma brucei epsilon tubulin 0.0352 0.4792 0.5993
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Trichomonas vaginalis tubulin, putative 0.0174 0.2331 0.2907
Loa Loa (eye worm) beta-lactamase 0.003 0.0337 0.0421
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0052 0.0647 0.2455
Leishmania major phosphatidylinositol 3-kinase, putative 0.0007 0.0012 0.0009
Echinococcus granulosus growth factor receptor bound protein 2 0.0006 0.0002 0.0003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0193 0.0235
Brugia malayi Patched related family protein 10 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Leishmania major trypanothione reductase 0.0021 0.0208 0.0253
Mycobacterium ulcerans hypothetical protein 0.001 0.0065 0.0224
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Treponema pallidum NADH oxidase 0.0007 0.002 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0021 0.0213 0.0266
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Loa Loa (eye worm) hypothetical protein 0.0009 0.0048 0.006
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0212 0.0266
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.3124 0.3124
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.003 0.0337 0.0421
Brugia malayi hypothetical protein 0.0021 0.0213 0.0263
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Brugia malayi CHE-14 protein 0.0055 0.0678 0.0846
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0123
Plasmodium vivax thioredoxin reductase, putative 0.0021 0.0208 0.0252
Giardia lamblia High cysteine protein 0.0011 0.0072 0.0065
Loa Loa (eye worm) tubulin alpha 2 0.0286 0.3885 0.4864
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0029 0.0321 0.0402
Giardia lamblia Gamma tubulin 0.0352 0.4797 0.5995
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0011 0.0069 0.0198
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0512 0.0638
Onchocerca volvulus 0.001 0.0065 0.0178
Echinococcus granulosus neuropeptide receptor A26 0.0206 0.2775 0.3474
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0466 0.0466
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Schistosoma mansoni survival motor neuron protein 0.0021 0.0213 0.0264
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0052 0.0647 0.3006
Brugia malayi cytoplasmic intermediate filament protein 0.0006 0.0009 0.0008
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0008 0.0036 0.0036
Loa Loa (eye worm) BEN-1 protein 0.0583 0.7988 1
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Echinococcus multilocularis roundabout 2 0.0013 0.0102 0.0102
Brugia malayi Cell division protein ftsZ 0.015 0.2003 0.2506
Brugia malayi beta-tubulin, identical 0.0583 0.7988 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0007 0.002 0.0019
Giardia lamblia Sgs1 DNA helicase, putative 0.0013 0.0095 0.0093
Brugia malayi acetyltransferase, GNAT family protein 0.0067 0.0845 0.1055
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0395
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0337 0.0406
Brugia malayi hypothetical protein 0.0019 0.0178 0.022
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0011 0.0072 0.0075
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0456
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0512 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) hypothetical protein 0.0103 0.1354 0.1695
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Loa Loa (eye worm) MH2 domain-containing protein 0.0007 0.0022 0.0028
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0204 0.0244
Brugia malayi MH2 domain containing protein 0.0007 0.0022 0.0025
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0212 0.0212
Schistosoma mansoni tyrosine kinase 0.0043 0.0522 0.065
Echinococcus granulosus tubulin delta chain 0.015 0.2003 0.2508
Schistosoma mansoni thyroid hormone receptor 0.0094 0.1229 0.1536
Echinococcus multilocularis tyrosine protein kinase Srms 0.0018 0.0172 0.0172
Brugia malayi sulfakinin receptor protein 0.0098 0.1275 0.1593
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Entamoeba histolytica tubulin family protein 0.0583 0.7988 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0032 0.0369 0.046
Brugia malayi Papain family cysteine protease containing protein 0.0007 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.3775 0.4725
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0466 0.0584
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0085 0.0106
Echinococcus multilocularis transfer RNA-Lys 0.0016 0.0139 0.0139
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0387
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0011 0.0069 0.0084
Brugia malayi steroid hormone receptor 0.0039 0.0466 0.0581
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0032 0.0369 0.0456
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) tubulin alpha 2 0.0108 0.1419 0.1776
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0369 0.0369
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0108 0.0135
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0011 0.0069 0.0069
Mycobacterium tuberculosis Probable hydrolase 0.003 0.0337 0.1237
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.002 0.0204 0.0248
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0007 0.0012 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Plasmodium vivax vivapain-2 0.0007 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0095 0.0118
Trichomonas vaginalis tubulin epsilon chain, putative 0.0437 0.5967 0.7467
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Brugia malayi beta-lactamase family protein 0.003 0.0337 0.0419
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0193 0.0242
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0193 0.0239
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0178 0.0178
Echinococcus multilocularis beta tubulin 0.0583 0.7988 0.7988
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0212 0.0254
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0032 0.0369 0.0462
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0337 0.0419
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0065 0.0224
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0082 0.1059 0.1312
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Plasmodium falciparum cysteine proteinase falcipain 3 0.0007 0.0023 0.0003
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0286 0.3885 0.4856
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0583 0.7988 0.7988
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0368 0.0458
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0368 0.0368
Echinococcus multilocularis tubulin alpha 0.0328 0.447 0.447
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Toxoplasma gondii beta-tubulin, putative 0.0583 0.7988 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.024
Loa Loa (eye worm) tubulin beta-1 chain 0.0583 0.7988 1
Echinococcus multilocularis fibrillin 1 0.0011 0.0072 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.01 0.0122
Loa Loa (eye worm) hypothetical protein 0.0033 0.0373 0.0466
Plasmodium vivax acyl-CoA synthetase, putative 0.0008 0.0028 0.0028
Echinococcus granulosus intermediate filament protein 0.0012 0.0085 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0178 0.022
Entamoeba histolytica cysteine protease, putative 0.0007 0.0023 0.0021
Echinococcus granulosus cathepsin L cysteine proteinase 0.0007 0.0023 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Toxoplasma gondii isocitrate dehydrogenase 0.002 0.0204 0.0244
Echinococcus multilocularis beta LACTamase domain containing family member 0.003 0.0337 0.0337
Brugia malayi hypoxia-induced factor 1 0.0066 0.0833 0.1041
Loa Loa (eye worm) integrin beta-2 0.0512 0.7006 0.8772
Trichomonas vaginalis tubulin beta chain, putative 0.0178 0.2388 0.2978
Loa Loa (eye worm) hypothetical protein 0.0037 0.0432 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0915 0.0915
Schistosoma mansoni hypothetical protein 0.0045 0.0548 0.0683
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Brugia malayi nuclear hormone receptor 0.0019 0.0178 0.022
Trichomonas vaginalis tubulin epsilon chain, putative 0.0583 0.7988 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0127 0.1684 0.2109
Loa Loa (eye worm) hypothetical protein 0.0127 0.1684 0.2109
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.003 0.0337 0.0419
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0178 0.2388 0.2978
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0212 0.0749
Entamoeba histolytica acetyltransferase, GNAT family 0.0018 0.017 0.0205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi Tubulin alpha chain 0.0437 0.5967 0.747
Schistosoma mansoni hypothetical protein 0.0029 0.0325 0.0404
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0209 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0082 0.0087
Toxoplasma gondii patched family protein 0.0008 0.0028 0.0023
Echinococcus multilocularis peroxisome assembly protein 26 0.0437 0.5967 0.5967
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0466 0.0581
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus multilocularis neuroglian 0.001 0.0066 0.0066
Echinococcus multilocularis integrin alpha ps 0.0028 0.0304 0.0304
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) tubulin alpha chain 0.0437 0.5967 0.747
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Onchocerca volvulus 0.003 0.0337 0.1328
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0006 0.001 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.015 0.2003 0.2496
Entamoeba histolytica protein kinase, putative 0.0015 0.0131 0.0156
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0466 0.0581
Leishmania major eukaryotic initiation factor 4a, putative 0.0011 0.0069 0.008
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0269 0.033
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0269 0.1252
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0466 0.0584
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0178 0.0223
Echinococcus granulosus integrin alpha ps 0.0028 0.0304 0.0381
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Brugia malayi conserved hypotetical protein 0.0019 0.0178 0.022
Plasmodium vivax delta tubulin, putative 0.015 0.2003 0.2502
Loa Loa (eye worm) hypothetical protein 0.0028 0.0304 0.0381
Schistosoma mansoni cpg binding protein 0.0013 0.0105 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0032 0.0369 0.0447
Leishmania major hypothetical protein, conserved 0.003 0.0337 0.0415
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.011 0.0131
Onchocerca volvulus 0.0008 0.0028 0.0023
Echinococcus granulosus integrin beta 2 0.0378 0.5149 0.6447
Echinococcus granulosus insulin receptor 0.0043 0.0522 0.0653
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis integrin beta 2 0.0378 0.5149 0.5149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0084 0.0089
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0466 0.0466
Giardia lamblia Histone acetyltransferase GCN5 0.0018 0.017 0.0188
Loa Loa (eye worm) BEN-1 protein 0.0583 0.7988 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0269 0.0972
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Echinococcus granulosus survival motor neuron protein 1 0.0103 0.1354 0.1695
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus multilocularis tumor protein p63 0.0148 0.1968 0.1968
Onchocerca volvulus 0.0013 0.0095 0.0307
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.019
Schistosoma mansoni smad1 5 8 and 0.0007 0.0022 0.0025
Schistosoma mansoni zinc finger protein 0.0019 0.0178 0.022
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0278 0.3775 0.4726
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Mycobacterium ulcerans fatty-acid-CoA ligase 0.001 0.0065 0.0224
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0007 0.002 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Trichomonas vaginalis DNA helicase recq1, putative 0.0018 0.017 0.0198
Onchocerca volvulus 0.0022 0.0221 0.0838
Toxoplasma gondii beta-1 tubulin, putative 0.0583 0.7988 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.002 0.0193 0.023
Echinococcus granulosus L aminoadipate semialdehyde 0.0075 0.0955 0.1195
Giardia lamblia Tenascin-like 0.0011 0.0072 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus granulosus tumor protein p63 0.0148 0.1968 0.2464
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0013 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Treponema pallidum cell division protein FtsZ 0.015 0.2003 1
Echinococcus multilocularis transcription factor Dp 1 0.0017 0.0153 0.0153
Brugia malayi SPARC precursor 0.0017 0.0152 0.0187
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Entamoeba histolytica hypothetical protein 0.0021 0.0212 0.0258
Leishmania major cysteine peptidase A (CPA) 0.0007 0.0023 0.0021
Mycobacterium ulcerans cell division protein FtsZ 0.015 0.2003 1
Toxoplasma gondii tubulin, putative 0.0023 0.0244 0.0294
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0025 0.0269 0.0334
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0107
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0212 0.0266
Echinococcus multilocularis adam 0.0011 0.0072 0.0072
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Plasmodium falciparum alpha tubulin 2 0.0437 0.5967 0.7464
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0029 0.0321 0.0394
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.003 0.0337 0.1237
Echinococcus granulosus bloom syndrome protein 0.0018 0.017 0.0213
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0011 0.0069 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Brugia malayi Integrin beta pat-3 precursor 0.0512 0.7006 0.8771
Loa Loa (eye worm) phosphatidylinositol 3 0.0007 0.0012 0.0016
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0018 0.0172 0.0172
Mycobacterium leprae cell division protein FtsZ 0.015 0.2003 1
Echinococcus granulosus twitchin 0.0011 0.0074 0.0092
Echinococcus multilocularis tubulin alpha 1C chain 0.0437 0.5967 0.5967
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0212 0.024
Loa Loa (eye worm) agrin synaptic family protein 0.0017 0.0152 0.019
Leishmania major zeta tubulin, putative 0.0394 0.5383 0.6737
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Schistosoma mansoni hypothetical protein 0.0179 0.2399 0.3001
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Mycobacterium tuberculosis Probable oxidoreductase 0.0052 0.0647 0.2455
Loa Loa (eye worm) hypothetical protein 0.0098 0.1275 0.1596
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0466 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Onchocerca volvulus 0.003 0.0337 0.1328
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0337 0.0406
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0466 0.0581
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0009 0.0048 0.0057
Schistosoma mansoni nephrin 0.0012 0.0083 0.0102
Echinococcus granulosus roundabout 2 0.0013 0.0102 0.0127
Trichomonas vaginalis penicillin-binding protein, putative 0.003 0.0337 0.0406
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0328 0.447 0.5591
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Trypanosoma brucei trypanothione reductase 0.0021 0.0208 0.0245
Echinococcus granulosus tubulin epsilon chain 0.0352 0.4792 0.6
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0096 0.1245 0.1245
Brugia malayi alpha-tubulin 0.0437 0.5967 0.747
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0193 0.0235
Schistosoma mansoni integrin beta subunit 0.0299 0.406 0.5082
Schistosoma mansoni aryl hydrocarbon receptor 0.0021 0.0216 0.0268
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Onchocerca volvulus 0.0024 0.0259 0.0999
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0011 0.0069 0.0075
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0013 0.01 0.0125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.012 0.1577 0.1975
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0193 0.0239
Echinococcus granulosus tubulin alpha 0.0328 0.447 0.5596
Schistosoma mansoni organic anion transporter 0.0024 0.0259 0.0322
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0108 0.0133
Toxoplasma gondii ABC1 family protein 0.003 0.0337 0.041
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Trypanosoma brucei epsilon tubulin 0.0328 0.447 0.5589
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0095 0.0116
Mycobacterium tuberculosis Probable lipase LipD 0.003 0.0337 0.1237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0466 0.0581
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0009 0.005 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Brugia malayi hypothetical protein 0.0021 0.0209 0.0259
Brugia malayi Bloom's syndrome protein homolog 0.0018 0.017 0.0211
Loa Loa (eye worm) hypothetical protein 0.0007 0.0023 0.0028
Leishmania major beta tubulin 0.0583 0.7988 1
Toxoplasma gondii transporter, major facilitator family protein 0.0024 0.0259 0.0313
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Onchocerca volvulus 0.012 0.1577 0.6574
Echinococcus multilocularis integrin alpha ps 0.0058 0.072 0.072
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0029 0.0321 0.0399
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Brugia malayi Myosin head containing protein 0.0008 0.0028 0.0032
Onchocerca volvulus 0.0017 0.0152 0.0546
Schistosoma mansoni tyrosine kinase 0.0072 0.0915 0.1143
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0466 0.0581
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0466 0.1876
Plasmodium falciparum tubulin epsilon chain, putative 0.0352 0.4792 0.5989
Mycobacterium tuberculosis Probable esterase LipL 0.003 0.0337 0.1237
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0193 0.0226
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0466 0.0581
Trypanosoma cruzi zeta tubulin, putative 0.0394 0.5383 0.6737
Schistosoma mansoni smad 0.0007 0.0022 0.0025
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0013 0.0095 0.0118
Trichomonas vaginalis esterase, putative 0.003 0.0337 0.0406
Schistosoma mansoni cellular tumor antigen P53 0.0022 0.0221 0.0274
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.002 0.0193 0.023
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Echinococcus granulosus thioredoxin glutathione reductase 0.0021 0.0208 0.026
Schistosoma mansoni tubulin subunit delta 0.015 0.2003 0.2506
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0193 0.0235
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0065 0.0174
Onchocerca volvulus 0.0024 0.0259 0.0999
Brugia malayi tubulin alpha chain - mouse 0.0437 0.5967 0.747
Schistosoma mansoni hypothetical protein 0.0032 0.0368 0.0458
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0466 0.0581
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0032 0.0369 0.0455
Mycobacterium ulcerans putative regulatory protein 0.0016 0.0139 0.0599
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Schistosoma mansoni blooms syndrome DNA helicase 0.0006 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Toxoplasma gondii NADPH-glutathione reductase 0.0007 0.002 0.0014
Loa Loa (eye worm) TK/INSR protein kinase 0.0043 0.0522 0.0653
Echinococcus granulosus fibrillin 1 0.0011 0.0072 0.009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) tubulin alpha-2 chain 0.0437 0.5967 0.747
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0011 0.0069 0.0079
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0082
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.003 0.0337 0.1237
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Schistosoma mansoni alpha tubulin 0.0437 0.5967 0.747
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0466 0.1876
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.132 0.1652
Echinococcus multilocularis protein dispatched 1 0.0062 0.0785 0.0785
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.1014
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0373 0.046
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Mycobacterium tuberculosis Probable dehydrogenase 0.0047 0.0575 0.2169
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0373 0.0442
Giardia lamblia Tenascin-37 0.0011 0.0072 0.0065
Trypanosoma cruzi tubulin gamma chain 0.0352 0.4797 0.6003
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.002 0.0204 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0209 0.0259
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Loa Loa (eye worm) TK protein kinase 0.0047 0.057 0.0713
Echinococcus multilocularis lamin dm0 0.0012 0.0085 0.0085
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Plasmodium vivax tubulin beta chain, putative 0.0583 0.7988 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0017 0.0155 0.0169
Trichomonas vaginalis tubulin alpha chain, putative 0.0328 0.447 0.5589
Echinococcus multilocularis tubulin subunit beta 0.0583 0.7988 0.7988
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Entamoeba histolytica acyl-coA synthetase, putative 0.001 0.0065 0.0073
Plasmodium vivax histone acetyltransferase GCN5, putative 0.002 0.0193 0.0234
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0212 0.0965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0021 0.0213 0.0263
Loa Loa (eye worm) TK protein kinase 0.0018 0.0172 0.0215
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Echinococcus granulosus eukaryotic initiation factor 4A 0.0011 0.0069 0.0087
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0466 0.0581
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Trichomonas vaginalis tubulin, putative 0.0178 0.2388 0.2978
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.002 0.0204 0.0719
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Loa Loa (eye worm) alpha-tubulin 0.0437 0.5967 0.747
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0192 0.2575 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Trichomonas vaginalis tubulin, putative 0.0583 0.7988 1
Trypanosoma cruzi trypanothione reductase, putative 0.0007 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Echinococcus multilocularis thyroid hormone receptor alpha 0.0094 0.1229 0.1229
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0106
Onchocerca volvulus Protein patched homolog 0.0008 0.0028 0.0023
Plasmodium vivax tubulin gamma chain, putative 0.0352 0.4797 0.6003
Echinococcus multilocularis tyrosine protein kinase HCK 0.0015 0.0131 0.0131
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.001 0.0065 0.0224
Giardia lamblia hypothetical protein 0.0011 0.0072 0.0065
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Loa Loa (eye worm) hypothetical protein 0.0067 0.0848 0.1062
Brugia malayi Tubulin beta chain 0.015 0.2003 0.2506
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0178 0.0223
Mycobacterium tuberculosis Probable conserved lipoprotein 0.003 0.0337 0.1237
Entamoeba histolytica recQ family helicase, putative 0.0014 0.011 0.013
Onchocerca volvulus 0.0008 0.0028 0.0023
Leishmania major delta tubulin, putative 0.0296 0.4025 0.5036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0466 0.0581
Brugia malayi prostaglandin transporter 0.0024 0.0259 0.0322
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0466 0.0581
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus granulosus neuroglian 0.001 0.0066 0.0083
Trypanosoma brucei alpha tubulin, putative 0.0178 0.2388 0.2978
Echinococcus multilocularis tyrosine protein kinase Blk 0.0018 0.0172 0.0172
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0178 0.0223
Schistosoma mansoni cathepsin F (C01 family) 0.0007 0.0023 0.0026
Leishmania major hypothetical protein, conserved 0.0033 0.0373 0.046
Trichomonas vaginalis glucosylceramidase, putative 0.0119 0.1567 0.1949
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0466 0.0584
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0209 0.0262
Echinococcus multilocularis integrin alpha ps 0.0058 0.072 0.072
Mycobacterium tuberculosis Conserved protein 0.003 0.0337 0.1237
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Onchocerca volvulus 0.0008 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0259 0.3501 0.4383
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus granulosus transcription factor Dp 1 0.0017 0.0153 0.0191
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Brugia malayi hypothetical protein 0.0021 0.0209 0.0259
Toxoplasma gondii alpha tubulin TUBA1 0.0437 0.5967 0.7467
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0007 0.0023 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0193 0.0235
Echinococcus granulosus mothers against decapentaplegic 5 0.0007 0.0022 0.0028
Schistosoma mansoni tyrosine kinase 0.0069 0.0882 0.1101
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Echinococcus granulosus lamin 0.0012 0.0085 0.0106
Schistosoma mansoni nuclear receptor 0.0019 0.0178 0.022
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus multilocularis tubulin delta chain 0.015 0.2003 0.2003
Entamoeba histolytica cysteine proteinase, putative 0.0007 0.0023 0.0021
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0212 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0007 0.0022 0.0022
Echinococcus multilocularis epidermal growth factor receptor 0.0132 0.1751 0.1751
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus multilocularis tubulin subunit TubB 0.0437 0.5967 0.5967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0124 0.0139
Trichomonas vaginalis D-aminoacylase, putative 0.003 0.0337 0.0406
Echinococcus granulosus ubiquitin specific protease 41 0.0032 0.0369 0.0462
Leishmania major beta tubulin 0.0583 0.7988 1
Echinococcus multilocularis cysteine protease 0.0007 0.0023 0.0023
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0212 0.0254
Echinococcus granulosus fibroblast growth factor receptor 4 0.0046 0.0552 0.0691
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0178 0.0658
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Echinococcus multilocularis Smad4 0.0007 0.0022 0.0022
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Trichomonas vaginalis tubulin, putative 0.0178 0.2388 0.2978
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0212 0.0212
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Loa Loa (eye worm) glutaminase 0.0108 0.1419 0.1777
Entamoeba histolytica acyl-CoA synthetase, putative 0.001 0.0065 0.0073
Echinococcus multilocularis cathepsin L cysteine protease 0.0007 0.0023 0.0023
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Trichomonas vaginalis hypothetical protein 0.0011 0.0072 0.0075
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0466 0.0466
Plasmodium falciparum tubulin delta chain, putative 0.015 0.2003 0.2489
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0124 0.0124
Trypanosoma brucei isocitrate dehydrogenase, putative 0.002 0.0204 0.024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0011 0.0069 0.0191
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Echinococcus multilocularis follistatin 0.0017 0.0152 0.0152
Toxoplasma gondii cathepsin CPL 0.0007 0.0023 0.0016
Plasmodium falciparum acyl-CoA synthetase 0.0008 0.0028 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.002 0.001
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0011 0.0069 0.0061
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0212 0.0965
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0108 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.057 0.0711
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.001 0.0065 0.0174
Loa Loa (eye worm) hypothetical protein 0.0011 0.0072 0.009
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0212 0.0212
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0437 0.5967 0.7467
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0025 0.0274 0.0337
Echinococcus granulosus adam 0.0011 0.0072 0.009
Brugia malayi nuclear receptor NHR-67 0.0019 0.0178 0.022
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0081
Echinococcus granulosus peroxisome assembly protein 26 0.0437 0.5967 0.747
Onchocerca volvulus 0.0012 0.0085 0.0262
Trypanosoma brucei PAB1-binding protein , putative 0.0033 0.0373 0.0452
Schistosoma mansoni tyrosine kinase 0.0008 0.0036 0.0042
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Echinococcus multilocularis insulin receptor 0.0043 0.0522 0.0522
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0178 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.015 0.2003 0.2496
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0466 0.0584
Echinococcus granulosus fibrillin 2 0.0011 0.0072 0.009
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0178 0.0178
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.1405 0.1759
Onchocerca volvulus Putative organic anion transporter 0.0024 0.0259 0.0999
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Brugia malayi glutathione reductase 0.0021 0.0208 0.0257
Trichomonas vaginalis tubulin gamma chain, putative 0.0583 0.7988 1
Onchocerca volvulus 0.0024 0.0259 0.0999
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0029 0.0321 0.0395
Brugia malayi hypothetical protein 0.0024 0.0259 0.0322
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0024 0.0259 0.0259
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0178 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0466 0.0584
Loa Loa (eye worm) hypothetical protein 0.0097 0.1269 0.1588
Loa Loa (eye worm) patched family protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0079 0.101 0.1264
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0011 0.0069 0.0071
Echinococcus multilocularis expressed conserved protein 0.012 0.1577 0.1577
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus granulosus tubulin alpha 1C chain 0.0437 0.5967 0.747
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0466 0.0581
Schistosoma mansoni DNA helicase recq5 0.0013 0.0095 0.0116
Loa Loa (eye worm) tubulin beta-4 chain 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Trypanosoma brucei beta tubulin 0.0583 0.7988 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0127 0.1684 0.2107
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0007 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0178 0.022
Entamoeba histolytica tubulin gamma chain 0.0352 0.4797 0.6003
Echinococcus granulosus integrin alpha 3 0.0099 0.1287 0.1611
Plasmodium falciparum lipid/sterol:H+ symporter 0.0008 0.0028 0.001
Echinococcus granulosus tubulin alpha 3 chain 0.0437 0.5967 0.747
Giardia lamblia Beta tubulin 0.0583 0.7988 1
Echinococcus granulosus Solute carrier organic anion transporter family 0.0024 0.0259 0.0324
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.002 0.001
Echinococcus multilocularis cathepsin L cysteine protease 0.0007 0.0023 0.0023
Toxoplasma gondii alpha-tubulin I, putative 0.0437 0.5967 0.7467
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0066 0.0071
Echinococcus granulosus c src tyrosine kinase 0.0008 0.0036 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.0085 0.0107
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Toxoplasma gondii LsmAD domain-containing protein 0.0033 0.0373 0.0455
Echinococcus multilocularis 0.004 0.048 0.048
Echinococcus multilocularis cysteine protease 0.0007 0.0023 0.0023
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0212 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Brugia malayi nuclear receptor RXR 0.0021 0.0209 0.0259
Schistosoma mansoni thyroid hormone receptor 0.0094 0.1229 0.1536
Leishmania major beta tubulin 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.002 0.0019
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0212 0.0212
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Echinococcus granulosus Tubulin alpha 1 chain 0.0437 0.5967 0.747
Trypanosoma cruzi tubulin delta chain 0.0296 0.4025 0.5036
Schistosoma mansoni tubulin subunit alpha 0.0437 0.5967 0.747
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0193 0.0235
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0032 0.0369 0.0438
Brugia malayi Tubulin alpha chain 0.015 0.2003 0.2506
Schistosoma mansoni integrin alpha-ps 0.003 0.0337 0.0419
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0466 0.0581
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0209 0.0259
Giardia lamblia Neurogenic locus Notch protein precursor 0.0011 0.0072 0.0065
Echinococcus granulosus tubulin beta 4A class IVa 0.0583 0.7988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0007 0.002 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0209 0.0262
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.0204 0.0204
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0583 0.7988 0.7988
Brugia malayi EGF-like domain containing protein 0.0011 0.0072 0.0087
Trypanosoma cruzi zeta tubulin, putative 0.0394 0.5383 0.6737
Mycobacterium ulcerans esterase/lipase LipP 0.003 0.0337 0.1594
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0182 0.2441 0.2441
Leishmania major beta tubulin 0.0583 0.7988 1
Brugia malayi secreted modular calcium-binding protein 1 0.0017 0.0152 0.0187
Trypanosoma cruzi MFS transporter, putative 0.0024 0.0259 0.0318
Echinococcus multilocularis agrin 0.0017 0.0152 0.0152
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.3124 0.3911
Brugia malayi CXXC zinc finger family protein 0.0013 0.0095 0.0116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0583 0.7988 1
Trypanosoma brucei alpha tubulin 0.0437 0.5967 0.7467
Onchocerca volvulus 0.0019 0.0178 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0104 0.0114
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0032 0.0369 0.0447
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0007 0.0023 0.0028
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0178 0.022
Schistosoma mansoni hypothetical protein 0.0053 0.0651 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0138 0.0157
Echinococcus multilocularis ubiquitin specific protease 41 0.0032 0.0369 0.0369
Echinococcus granulosus defective proboscis extension response 0.0009 0.0048 0.006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0106
Leishmania major beta tubulin 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Entamoeba histolytica recQ family DNA helicase 0.0006 0.001 0.0004
Loa Loa (eye worm) DR-78 0.0019 0.0178 0.0223
Toxoplasma gondii protease inhibitor PI2 0.0017 0.0152 0.0178
Entamoeba histolytica hypothetical protein 0.0032 0.0368 0.0454
Echinococcus multilocularis integrin alpha 3 0.0099 0.1287 0.1287
Echinococcus multilocularis Niemann Pick C1 protein 0.0127 0.1684 0.1684
Schistosoma mansoni Smad4 0.0007 0.0022 0.0025
Echinococcus multilocularis tubulin alpha chain 0.0437 0.5967 0.5967
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0007 0.0012 0.0009
Echinococcus granulosus tubulin alpha chain 0.0437 0.5967 0.747
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0466 0.0581
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0466 0.0466
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0023 0.0245 0.0307
Trichomonas vaginalis tubulin gamma chain, putative 0.0352 0.4797 0.5999
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Echinococcus multilocularis geminin 0.0219 0.2956 0.2956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trichomonas vaginalis tubulin gamma chain, putative 0.0352 0.4792 0.5993
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.002 0.0204 0.0249
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0178 0.0223
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.1405 0.1759
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0085 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Schistosoma mansoni hypothetical protein 0.0021 0.0213 0.0264
Schistosoma mansoni tubulin subunit beta 0.015 0.2003 0.2506
Loa Loa (eye worm) hypothetical protein 0.0071 0.0904 0.1132
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0007 0.002 0.001
Echinococcus multilocularis Tubulin alpha 1 chain 0.0437 0.5967 0.5967
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0055 0.0684 0.0856
Echinococcus granulosus cathepsin l1 0.0007 0.0023 0.0028
Schistosoma mansoni tyrosine kinase 0.0072 0.0915 0.1143
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0178 0.0178
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Loa Loa (eye worm) TK protein kinase 0.0015 0.0131 0.0164
Echinococcus granulosus Tubulin beta 2C chain 0.0583 0.7988 1
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Schistosoma mansoni patched 1 0.0055 0.0678 0.0846
Loa Loa (eye worm) hypothetical protein 0.0012 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.003 0.0337 0.0421
Loa Loa (eye worm) beta-tubulin 0.0583 0.7988 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0512 0.0641
Plasmodium falciparum eukaryotic initiation factor 4A 0.0011 0.0069 0.0061
Onchocerca volvulus Protein patched homolog 0.0008 0.0028 0.0023
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trypanosoma brucei epsilon tubulin 0.0352 0.4792 0.5993
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Plasmodium vivax glutathione reductase, putative 0.0021 0.0208 0.0252
Loa Loa (eye worm) hypothetical protein 0.0039 0.0466 0.0584
Brugia malayi AMP-binding enzyme family protein 0.001 0.0065 0.0078
Echinococcus multilocularis cpg binding protein 0.0013 0.0105 0.0105
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0466 0.0584
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0009 0.0048 0.0057
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0021 0.0212 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0259 0.3501 0.4383
Entamoeba histolytica tubulin alpha-1 chain 0.0437 0.5967 0.7469
Leishmania major gamma-tubulin 0.0352 0.4797 0.6003
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Echinococcus multilocularis Immunoglobulin 0.0009 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Giardia lamblia Epsilon tubulin 0.0174 0.2326 0.2894
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0008 0.0028 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Plasmodium vivax tubulin alpha chain, putative 0.0437 0.5967 0.7469
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0139 0.0174
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0915 0.1146
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0055 0.0684 0.0684
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0308 0.0379
Loa Loa (eye worm) tubulin beta-2A chain 0.0583 0.7988 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0009 0.0048 0.0048
Schistosoma mansoni organic anion transporter 0.0024 0.0259 0.0322
Mycobacterium ulcerans hypothetical protein 0.003 0.0337 0.1594
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0466 0.0581
Echinococcus granulosus TGF beta signal transducer SmadC 0.0007 0.0022 0.0028
Leishmania major beta tubulin 0.0583 0.7988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0193 0.0227
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) RecQ helicase 0.0018 0.017 0.0213
Echinococcus granulosus single minded 2 0.0016 0.0139 0.0174
Brugia malayi Furin-like cysteine rich region family protein 0.0132 0.1751 0.219
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0065 0.0079
Echinococcus multilocularis smad 0.0007 0.0022 0.0022
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0193 0.0227
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0021 0.0208 0.0733
Loa Loa (eye worm) hypothetical protein 0.001 0.0066 0.0083
Echinococcus multilocularis expressed protein 0.0017 0.0152 0.0152
Mycobacterium leprae conserved hypothetical protein 0.003 0.0337 0.1402
Onchocerca volvulus 0.0008 0.0028 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0032 0.0369 0.046
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0008 0.0028 0.0041
Echinococcus multilocularis isocitrate dehydrogenase 0.002 0.0204 0.0204
Mycobacterium tuberculosis Cell division protein FtsZ 0.015 0.2003 0.7762
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0008 0.0034 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0308 0.037
Trichomonas vaginalis tubulin alpha chain, putative 0.0178 0.2388 0.2978
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0466 0.0584
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.0324
Brugia malayi Tubulin beta chain 0.0178 0.2388 0.2987
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Echinococcus granulosus histone acetyltransferase KAT2B 0.002 0.0193 0.0241
Schistosoma mansoni hypothetical protein 0.0014 0.0108 0.0133
Echinococcus multilocularis tyrosine protein kinase Abl 0.0043 0.0513 0.0513
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0072 0.0915 0.1146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0466 0.0584
Mycobacterium tuberculosis Probable reductase 0.0047 0.0575 0.2169
Brugia malayi hypothetical protein 0.001 0.0065 0.0079
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0017 0.0152 0.0178
Trypanosoma brucei tubulin delta chain 0.0296 0.4025 0.5031
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0373 0.0442
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0008 0.0036 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0269 0.1252
Schistosoma mansoni glutaminase 0.0108 0.1419 0.1774
Brugia malayi isocitrate dehydrogenase 0.002 0.0204 0.0253
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Echinococcus granulosus epidermal growth factor receptor 0.0132 0.1751 0.2192
Loa Loa (eye worm) Smad1 0.0007 0.0022 0.0028
Trichomonas vaginalis tubulin epsilon chain, putative 0.015 0.2003 0.2496
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Loa Loa (eye worm) TK/EGFR protein kinase 0.0132 0.1751 0.2192
Echinococcus granulosus tubulin alpha 3 chain 0.0437 0.5967 0.747
Echinococcus multilocularis tubulin alpha 3 chain 0.0437 0.5967 0.5967
Loa Loa (eye worm) tubulin gamma chain 0.0352 0.4797 0.6006
Echinococcus multilocularis c src tyrosine kinase 0.0008 0.0036 0.0036
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Trypanosoma cruzi target of rapamycin kinase 3 0.0016 0.0138 0.0166
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0212 0.0266
Brugia malayi eukaryotic initiation factor 4A 0.0011 0.0069 0.0084
Plasmodium falciparum tubulin gamma chain 0.0352 0.4797 0.5995
Loa Loa (eye worm) tubulin alpha chain 0.0437 0.5967 0.747
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0193 0.0235
Schistosoma mansoni lamin 0.0012 0.0085 0.0103
Schistosoma mansoni tyrosine kinase 0.0043 0.0522 0.065
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0047 0.0575 0.2169
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0021 0.0213 0.0213
Plasmodium vivax ataxin-2 like protein, putative 0.0033 0.0373 0.0459
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Toxoplasma gondii beta tubulin 0.0583 0.7988 1
Brugia malayi Fibronectin type III domain containing protein 0.001 0.0065 0.0079
Loa Loa (eye worm) hypothetical protein 0.0286 0.3885 0.4864
Echinococcus multilocularis neuropeptide s receptor 0.0206 0.2775 0.2775
Brugia malayi tubulin alpha-2 chain 0.0437 0.5967 0.747
Loa Loa (eye worm) hypothetical protein 0.0012 0.0082 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0007 0.0023 0.0013
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0212 0.0212
Leishmania major alpha tubulin 0.0437 0.5967 0.7469
Trypanosoma cruzi cysteine peptidase, putative 0.0007 0.0023 0.0021
Schistosoma mansoni cpg binding protein 0.0013 0.0095 0.0116
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0011 0.0069 0.008
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0006 0.001 0.0005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0029 0.0321 0.0399
Loa Loa (eye worm) hypothetical protein 0.0079 0.101 0.1264
Brugia malayi hypothetical protein 0.0008 0.0028 0.0032
Schistosoma mansoni tubulin subunit gamma 0.0352 0.4797 0.6005
Onchocerca volvulus 0.0039 0.0466 0.1876
Brugia malayi Patched family protein 0.0008 0.0028 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0013 0.0095 0.0118
Leishmania major 4-coumarate:coa ligase-like protein 0.001 0.0065 0.0074
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.002 0.0204 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0082 0.0087
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0124 0.0155
Loa Loa (eye worm) ctsf protein 0.0007 0.0023 0.0028
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0466 0.0581
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0129 0.1712 0.2141
Trichomonas vaginalis tubulin beta chain, putative 0.0437 0.5967 0.7467
Echinococcus multilocularis musashi 0.0012 0.0085 0.0085
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0075 0.0955 0.1193
Loa Loa (eye worm) hypothetical protein 0.0019 0.0178 0.0223
Giardia lamblia Tenascin precursor 0.0011 0.0072 0.0065
Brugia malayi Protein kinase domain containing protein 0.0043 0.0522 0.065
Leishmania major cathepsin L-like protease 0.0028 0.0308 0.0379
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0269 0.0269
Echinococcus granulosus smad 0.0007 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0262
Loa Loa (eye worm) tubulin alpha 2 0.0286 0.3885 0.4864
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0119 0.1567 0.1959
Onchocerca volvulus 0.0021 0.0213 0.0807
Brugia malayi glutaminase DH11.1 0.0108 0.1419 0.1774
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0068 0.007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0028 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0178 0.0178
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0047 0.0575 0.2169
Trypanosoma cruzi major cysteine proteinase, putative 0.0022 0.0225 0.0275
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0209 0.0209
Leishmania major cathepsin L-like protease 0.0007 0.0023 0.0021
Schistosoma mansoni agrin 0.0017 0.0152 0.0187
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.029 0.0361
Loa Loa (eye worm) hypoxia-induced factor 1 0.0066 0.0833 0.1043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0032 0.0369 0.0369
Echinococcus multilocularis beta tubulin 0.0583 0.7988 0.7988
Trichomonas vaginalis glucosylceramidase, putative 0.0078 0.1001 0.1239
Loa Loa (eye worm) hypothetical protein 0.0055 0.0678 0.0849
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0466 0.0584
Schistosoma mansoni coup transcription factor 0.0039 0.0466 0.0581
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0017 0.0152 0.0187
Entamoeba histolytica tubulin alpha chain, putative 0.0437 0.5967 0.7469
Schistosoma mansoni tyrosine kinase 0.0093 0.1204 0.1505
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0178 0.0223
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.1063 0.1331
Loa Loa (eye worm) fibroinase 0.0007 0.0023 0.0028
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0119 0.1567 0.1961
Brugia malayi latrophilin 2 splice variant baaae 0.0029 0.0325 0.0404
Echinococcus granulosus tyrosine protein kinase ABL1 0.0096 0.1245 0.1559
Schistosoma mansoni tyrosine kinase 0.0046 0.0552 0.0688
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0023 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.002 0.0019
Brugia malayi sodium-independent organic anion transporter family protein 0.0024 0.0259 0.0322
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0174 0.2326 0.2903
Loa Loa (eye worm) acetyltransferase 0.0067 0.0845 0.1057
Echinococcus multilocularis neuropeptide receptor A26 0.0206 0.2775 0.2775
Mycobacterium ulcerans glutaminase 0.0108 0.1419 0.7054
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0082 0.01
Giardia lamblia Alpha-tubulin 0.0437 0.5967 0.7464
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0011 0.0069 0.0084
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0466 0.0584
Echinococcus multilocularis protein jagged 2 0.0011 0.0072 0.0072
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0212 0.0266
Loa Loa (eye worm) TK/ABL protein kinase 0.0096 0.1245 0.1559
Echinococcus granulosus tubulin alpha 1C chain 0.0437 0.5967 0.747
Schistosoma mansoni tubulin subunit beta 0.0583 0.7988 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.007 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0098 0.0107
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0007 0.002 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0023 0.0009
Brugia malayi hypothetical protein 0.0071 0.091 0.1137
Echinococcus granulosus NCK adaptor protein 0.0006 0.0002 0.0003
Echinococcus granulosus Immunoglobulin 0.0009 0.0048 0.006
Loa Loa (eye worm) glutathione reductase 0.0021 0.0208 0.026
Brugia malayi nuclear receptor NHR-88 0.0039 0.0466 0.0581
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.019
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0212 0.025
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0045 0.0539 0.0675
Brugia malayi Tubulin alpha-2 chain 0.0437 0.5967 0.747
Echinococcus multilocularis L aminoadipate semialdehyde 0.0075 0.0955 0.0955
Trichomonas vaginalis glucosylceramidase, putative 0.0082 0.1059 0.1312
Mycobacterium ulcerans beta-lactamase 0.003 0.0337 0.1594
Brugia malayi Cathepsin L-like precursor 0.0007 0.0023 0.0026
Echinococcus multilocularis survival motor neuron protein 1 0.0103 0.1354 0.1354
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.002 0.0204 0.0204

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 5.78 Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP ChEMBL. 23416008
Kd (binding) = 1.66 uM Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP ChEMBL. 23416008
Kd (binding) = 1.66 uM Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance analysis ChEMBL. 23498914

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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