Detailed information for compound 1823173

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 354.309 | Formula: C16H18O9
  • H donors: 6 H acceptors: 8 LogP: -0.42 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(O[C@@H]1[C@H](O)C[C@](C[C@H]1O)(O)C(=O)O)/C=C/c1ccc(c(c1)O)O
  • InChi: 1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(21)25-14-11(19)6-16(24,15(22)23)7-12(14)20/h1-5,11-12,14,17-20,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16-/m1/s1
  • InChiKey: GYFFKZTYYAFCTR-QHEBTOHLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0165 0.1978 0.2477
Mycobacterium ulcerans polyketide synthase MbtD 0.0126 0.1456 0.1781
Echinococcus multilocularis c src tyrosine kinase 0.0016 0.0015 0.0027
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0103 0.1152 1
Loa Loa (eye worm) hypothetical protein 0.0178 0.2145 0.2416
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0032 0.0225 0.0395
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0769 0.334
Mycobacterium ulcerans acyl-CoA synthetase 0.0063 0.0629 0.0716
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0086 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.2157 0.3793
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0289 0.1602
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0025 0.0136 0.0115
Loa Loa (eye worm) hypothetical protein 0.005 0.0464 0.0523
Echinococcus granulosus down syndrome cell adhesion 0.0019 0.0058 0.0101
Echinococcus multilocularis importin subunit beta 1 0.0028 0.017 0.0299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0035 0.0257 0.1365
Onchocerca volvulus 0.0022 0.0091 0.0096
Mycobacterium ulcerans quinone reductase Qor 0.0025 0.0136 0.0082
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0025 0.0136 0.0136
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0289 0.1038
Schistosoma mansoni myosin-binding protein-related 0.0019 0.0058 0.0101
Brugia malayi beta-lactamase 0.0037 0.0289 0.0289
Schistosoma mansoni ap endonuclease 0.0021 0.0073 0.0128
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0035 0.0257 0.0452
Brugia malayi CXXC zinc finger family protein 0.0031 0.0215 0.0215
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0103 0.1152 1
Schistosoma mansoni cell adhesion molecule 0.0089 0.097 0.1705
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0016 0.0015 0.0027
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0289 0.0262
Trichomonas vaginalis ran, putative 0.0021 0.0073 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0289 0.0311
Onchocerca volvulus 0.0019 0.0058 0.0061
Brugia malayi hypothetical protein 0.0017 0.0022 0.0022
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0025 0.0136 0.0115
Echinococcus granulosus c src tyrosine kinase 0.0016 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0089 0.097 0.1092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0143 0.0337
Echinococcus granulosus defective proboscis extension response 0.0076 0.0803 0.1412
Leishmania major oxidoreductase-like protein 0.0025 0.0136 0.0305
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0345 0.0335
Toxoplasma gondii ABC1 family protein 0.0037 0.0289 0.0395
Mycobacterium ulcerans hypothetical protein 0.0041 0.0345 0.0351
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0019 0.0058 0.0101
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0129 0.1492 0.1854
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1423 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0143 0.0337
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0015 0.0027
Echinococcus granulosus acyl carrier protein mitochondrial 0.0041 0.0345 0.0607
Mycobacterium tuberculosis Conserved protein 0.0037 0.0289 0.0311
Echinococcus granulosus twitchin 0.0097 0.1071 0.1883
Echinococcus multilocularis down syndrome cell adhesion 0.0019 0.0058 0.0101
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0019 0.0058 0.0101
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.01 0.0207
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0289 0.0311
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0025 0.0136 0.0082
Echinococcus multilocularis Immunoglobulin 0.0076 0.0803 0.1412
Brugia malayi hypothetical protein 0.0026 0.0143 0.0143
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0397 0.5017 0.6376
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0086 0.0017
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0086 0.0151
Mycobacterium tuberculosis Possible dehydrogenase 0.0025 0.0136 0.0115
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0025 0.0136 0.0115
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0164 0.0288
Brugia malayi Prion-like- 0.0032 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0025 0.0136 0.0153
Mycobacterium ulcerans lipase LipD 0.0037 0.0289 0.0278
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0086 0.0151
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0103 0.1152 0.1298
Mycobacterium ulcerans thioesterase 0.0341 0.4285 0.5421
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0215 0.0242
Loa Loa (eye worm) TK/ROR protein kinase 0.0028 0.0164 0.0185
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0063 0.0629 0.0716
Echinococcus multilocularis snurportin 1 0.0299 0.3732 0.6562
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0435 0.5517 0.7016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Echinococcus multilocularis 0.0019 0.0058 0.0101
Brugia malayi Disorganized muscle protein 1 0.0019 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0164 0.0288
Echinococcus granulosus fibroblast growth factor receptor 4 0.0323 0.4055 0.7129
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0485 0.0562
Trypanosoma cruzi oxidoreductase, putative 0.0025 0.0136 0.0305
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Schistosoma mansoni cell adhesion molecule 0.0032 0.0225 0.0395
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0026 0.0142 0.0639
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.01 0.0134
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0289 0.0278
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0032 0.0225 0.0395
Entamoeba histolytica hypothetical protein 0.0023 0.01 0.0134
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0026 0.0142 0.0639
Brugia malayi Protein kinase domain containing protein 0.0179 0.2157 0.2157
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0126 0.1456 0.1808
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Echinococcus multilocularis titin 0.0019 0.0058 0.0101
Mycobacterium ulcerans polyketide synthase 0.0409 0.5182 0.6576
Plasmodium falciparum acyl carrier protein 0.0041 0.0345 0.2527
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0026 0.0142 0.0089
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Echinococcus granulosus dual specificity 0.0179 0.2157 0.3793
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0271 0.336 0.423
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0257 0.1365
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0032 0.0225 0.0395
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.017 0.0468
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0289 0.0508
Loa Loa (eye worm) acyl carrier protein 0.0041 0.0345 0.0389
Onchocerca volvulus 0.0074 0.0769 0.0809
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0076 0.0803 0.1412
Schistosoma mansoni tyrosine kinase 0.0016 0.0015 0.0027
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0103 0.1152 0.139
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0103 0.1152 0.518
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.0769 0.0926
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.002
Trichomonas vaginalis esterase, putative 0.0037 0.0289 0.1602
Onchocerca volvulus 0.0578 0.7396 0.7784
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.002
Toxoplasma gondii type I fatty acid synthase 0.0063 0.0627 0.1012
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0025 0.0136 0.0115
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0063 0.0627 0.0745
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0015 0.0002 0.0004
Echinococcus granulosus tyrosine protein kinase Src64B 0.0016 0.0015 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0769 0.0769
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0079 0.0837 0.1471
Echinococcus multilocularis tyrosine protein kinase Abl 0.0016 0.0015 0.0027
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0086 0.0051
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Mycobacterium ulcerans hypothetical protein 0.0037 0.0289 0.0278
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0289 0.0508
Schistosoma mansoni tyrosine kinase 0.004 0.0331 0.0581
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0025 0.0136 0.0305
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0041 0.0345 0.0389
Brugia malayi Immunoglobulin I-set domain containing protein 0.0343 0.431 0.431
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Brugia malayi Methyltransferase-like protein 4 0.0123 0.1423 0.1423
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0143 0.0128
Echinococcus granulosus tyrosine protein kinase Lyn 0.0017 0.0027 0.0048
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Mycobacterium ulcerans dehydrogenase 0.0025 0.0136 0.0082
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0769 0.0896
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0769 0.0769
Loa Loa (eye worm) hypothetical protein 0.069 0.888 1
Mycobacterium tuberculosis Conserved protein 0.0123 0.1423 0.1765
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0335 0.4202 0.533
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0385 0.0385
Schistosoma mansoni hemicentin 0.0019 0.0058 0.0101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0674 0.867 0.867
Echinococcus granulosus titin 0.0019 0.0058 0.0101
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0464 0.0464
Leishmania major zinc-binding dehydrogenase-like protein 0.0025 0.0136 0.0305
Brugia malayi hypothetical protein 0.0076 0.0803 0.0803
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0086 0.0017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Schistosoma mansoni vesicular amine transporter 0.0076 0.0803 0.1412
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0097
Loa Loa (eye worm) TK protein kinase 0.0343 0.431 0.4854
Schistosoma mansoni nephrin 0.0096 0.1059 0.1862
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0025 0.0136 0.0065
Mycobacterium ulcerans polyketide synthase Pks9 0.0271 0.336 0.423
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0086 0.0086
Schistosoma mansoni neuroglian 0.0032 0.0225 0.0395
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0016 0.0015 0.0027
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.0002
Onchocerca volvulus 0.0019 0.0058 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Echinococcus multilocularis roundabout 2 0.0032 0.0225 0.0395
Mycobacterium ulcerans fatty acid synthase Fas 0.0129 0.1492 0.1827
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0289 0.2003
Echinococcus granulosus basement membrane specific heparan sulfate 0.0015 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0289 0.0325
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0016 0.0015 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1362 0.1534
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0143 0.0651
Brugia malayi Peroxidasin 0.0032 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0159
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0016 0.0015 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Echinococcus multilocularis expressed protein 0.0034 0.0246 0.0432
Loa Loa (eye worm) CAMK protein kinase 0.002 0.007 0.0079
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0035 0.0257 0.0452
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0435 0.5517 0.7001
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Echinococcus multilocularis neuroglian 0.0096 0.1059 0.1862
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0025 0.0136 0.0305
Loa Loa (eye worm) hypothetical protein 0.0055 0.0524 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.002 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0063 0.0627 0.0706
Brugia malayi beta-lactamase family protein 0.0037 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.0524 0.0591
Schistosoma mansoni nephrin 0.0032 0.0225 0.0395
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0464 0.0523
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0086 0.0097
Schistosoma mansoni slit 0.0019 0.0058 0.0101
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0015 0.0002 0.0004
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0103 0.1152 0.1969
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0076 0.0803 0.1412
Schistosoma mansoni septate junction protein 0.0032 0.0225 0.0395
Entamoeba histolytica acyl-CoA synthetase, putative 0.0115 0.1312 0.5947
Schistosoma mansoni [ACP] S-malonyltransferase 0.0026 0.0142 0.0249
Brugia malayi MH2 domain containing protein 0.0119 0.1362 0.1362
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0063 0.0629 0.0716
Echinococcus multilocularis titin 0.002 0.007 0.0123
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0769 0.088
Mycobacterium ulcerans oxidoreductase 0.0025 0.0136 0.0082
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0073 0.0128
Echinococcus multilocularis tyrosine protein kinase otk 0.0032 0.0225 0.0395
Echinococcus multilocularis roundabout 2 0.0108 0.1226 0.2155
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0086 0.0123
Schistosoma mansoni hypothetical protein 0.0041 0.0345 0.0607
Echinococcus multilocularis insulin growth factor binding 0.0019 0.0058 0.0101
Leishmania major importin beta-1 subunit, putative 0.0023 0.01 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0289 0.1602
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0179 0.2157 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0089 0.097 0.1705
Mycobacterium ulcerans quinone oxidoreductase 0.0025 0.0136 0.0082
Toxoplasma gondii type I fatty acid synthase, putative 0.0438 0.5556 1
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0025 0.0136 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0485 0.0562
Mycobacterium leprae Polyketide synthase Pks13 0.0612 0.7843 1
Echinococcus multilocularis hemicentin 1 0.0032 0.0225 0.0395
Mycobacterium tuberculosis Conserved protein 0.0037 0.0289 0.0311
Trichomonas vaginalis rotamase, putative 0.0034 0.0246 0.1281
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0103 0.1152 0.2026
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0103 0.1152 1
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0435 0.5517 0.7016
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Echinococcus multilocularis hemicentin 1 0.0032 0.0225 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Loa Loa (eye worm) TK/ALK protein kinase 0.0023 0.0106 0.012
Schistosoma mansoni cpg binding protein 0.0031 0.0215 0.0378
Echinococcus multilocularis AMP dependent ligase 0.0044 0.0385 0.0677
Echinococcus multilocularis cpg binding protein 0.0033 0.0239 0.042
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0404 0.5113 0.5758
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0073 0.0128
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.0769 0.0896
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0063 0.0629 0.0748
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0003
Echinococcus granulosus nephrin 0.0019 0.0058 0.0101
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.0769 0.334
Echinococcus granulosus AMP dependent ligase 0.0044 0.0385 0.0677
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Toxoplasma gondii type I fatty acid synthase, putative 0.0291 0.3632 0.6491
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0032 0.0225 0.0395
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0769 0.334
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0385 0.0434
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0136 0.0115
Brugia malayi Importin beta-1 subunit 0.0028 0.017 0.017
Schistosoma mansoni tyrosine kinase 0.0016 0.0015 0.0027
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0103 0.1152 0.139
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Schistosoma mansoni cell adhesion molecule 0.0019 0.0058 0.0101
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0041 0.0345 0.0364
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0255 0.0255
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0409 0.5182 0.6587
Toxoplasma gondii acyl transferase domain-containing protein 0.0026 0.0142 0.0126
Echinococcus multilocularis transfer RNA-Phe 0.0019 0.0058 0.0101
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0025 0.0136 0.0082
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0289 0.0311
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0063 0.0629 0.0748
Onchocerca volvulus Putative alcohol dehydrogenase 0.0025 0.0136 0.0143
Loa Loa (eye worm) hypothetical protein 0.0025 0.0136 0.0153
Leishmania major acyl carrier protein, putative 0.0041 0.0345 0.1309
Echinococcus granulosus neuroglian 0.0096 0.1059 0.1862
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.002
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0246 0.0277
Mycobacterium tuberculosis Probable thioesterase TesA 0.0341 0.4285 0.5437
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.3732 0.4203
Echinococcus granulosus geminin 0.0338 0.4252 0.7475
Echinococcus granulosus neuroglian 0.0032 0.0225 0.0395
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.2913 0.3677
Trypanosoma brucei acyl transferase-like protein 0.0026 0.0142 0.0331
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0585 0.0934
Schistosoma mansoni nephrin related 0.0019 0.0058 0.0101
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.002
Echinococcus granulosus titin 0.0019 0.0058 0.0101
Schistosoma mansoni tyrosine kinase 0.0016 0.0015 0.0027
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0289 0.0289
Echinococcus granulosus NADH dehydrogenase 0.0041 0.0345 0.0607
Mycobacterium ulcerans Type I modular polyketide synthase 0.0409 0.5182 0.6576
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0143 0.0651
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0025 0.0136 0.0239
Onchocerca volvulus 0.0019 0.0058 0.0061
Echinococcus granulosus insulin growth factor binding 0.0019 0.0058 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0129 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0679 0.1193
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0044 0.0385 0.0402
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0225 0.0253
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0086 0.0098
Onchocerca volvulus 0.0022 0.0086 0.009
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0025 0.0136 0.0115
Echinococcus multilocularis NADH dehydrogenase 0.0041 0.0345 0.0607
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0409 0.5182 0.6587
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0329 0.4131 0.5223
Echinococcus multilocularis dual specificity 0.0179 0.2157 0.3793
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0257 0.1365
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0025 0.0136 0.0589
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0026 0.0142 0.0249
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.0769 0.0926
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0524 0.0613
Loa Loa (eye worm) hypothetical protein 0.0025 0.0136 0.0153
Echinococcus granulosus roundabout 2 0.0032 0.0225 0.0395
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0485 0.0562
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0041 0.0345 0.0384
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0448
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0086 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0143 0.0337
Mycobacterium ulcerans beta-lactamase 0.0037 0.0289 0.0278
Onchocerca volvulus Peroxidasin homolog 0.0019 0.0058 0.0061
Onchocerca volvulus 0.0031 0.0215 0.0227
Schistosoma mansoni cpg binding protein 0.0033 0.0239 0.042
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0025 0.0136 0.0305
Schistosoma mansoni acyl carrier protein 0.0041 0.0345 0.0607
Mycobacterium ulcerans oxidoreductase 0.0025 0.0136 0.0082
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0289 0.0278
Loa Loa (eye worm) disorganized muscle protein 1 0.0019 0.0058 0.0065
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0086 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.017 0.0192
Echinococcus granulosus snurportin 1 0.0299 0.3732 0.6562
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0086 0.0017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0041 0.0345 0.2527
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0179 0.2157 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0035 0.0257 0.0884
Loa Loa (eye worm) hypothetical protein 0.0108 0.1226 0.138
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1362 0.1534
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Brugia malayi Myb-like DNA-binding domain containing protein 0.0019 0.0058 0.0058
Onchocerca volvulus 0.0037 0.0289 0.0304
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.021 0.2561 0.4537
Schistosoma mansoni [ACP] S-malonyltransferase 0.0026 0.0142 0.0249
Onchocerca volvulus 0.0734 0.9451 0.9947
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0178 0.2145 0.2416
Entamoeba histolytica protein kinase domain containing protein 0.0179 0.2157 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0035 0.0258 0.0272
Leishmania major hypothetical protein, conserved 0.0026 0.0143 0.0337
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Brugia malayi Prion-like- 0.0019 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0016 0.0015 0.0027
Onchocerca volvulus 0.0019 0.0058 0.0061
Entamoeba histolytica Ran family GTPase 0.0021 0.0073 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0289 0.1038
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0016 0.0015 0.0027
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0409 0.5182 0.5182
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0041 0.0345 0.0345
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0435 0.5517 0.7016
Echinococcus granulosus leucine rich repeat containing protein 4 0.0019 0.0058 0.0101
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0035 0.0257 0.0452
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0015 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0035 0.0257 0.0884
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0041 0.0345 0.0384
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0179 0.2157 0.2429
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0397 0.5017 0.6376
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0235 0.078
Schistosoma mansoni hypothetical protein 0.0338 0.4252 0.7475
Echinococcus granulosus lachesin 0.0032 0.0225 0.0395
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0329 0.4131 0.5223
Mycobacterium leprae Probable lipase LipE 0.0037 0.0289 0.0262
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0025 0.0136 0.0305
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0103 0.1152 0.518
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0016 0.0015 0.0027
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0025 0.0136 0.0136
Onchocerca volvulus 0.0037 0.0289 0.0304
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0323 0.4055 0.7129
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0041 0.0345 0.1309
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0409 0.5182 0.657
Echinococcus granulosus Immunoglobulin 0.0076 0.0803 0.1412
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0179 0.2157 1
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0025 0.0136 0.0115
Giardia lamblia Methyltransferase like 2 0.0123 0.1423 1
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0063 0.0629 0.0716
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0063 0.0627 0.0745
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0026 0.0142 0.0639
Echinococcus granulosus titin 0.0019 0.0058 0.0101
Schistosoma mansoni hypothetical protein 0.0338 0.4252 0.7475
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0086 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0041 0.0345 0.0384
Plasmodium falciparum importin beta, putative 0.0028 0.017 0.0903
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0086 0.0051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0143 0.0161
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0082
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0025 0.0136 0.0115
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0073 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0627 0.0706
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0032 0.0225 0.0395
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0063 0.0629 0.0701
Loa Loa (eye worm) hypothetical protein 0.0055 0.0524 0.0591
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0073 0.0128
Brugia malayi Fibronectin type III domain containing protein 0.0076 0.0803 0.0803
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.002
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0019 0.0058 0.0101
Schistosoma mansoni roundabout 0.0032 0.0225 0.0395
Loa Loa (eye worm) hypothetical protein 0.0035 0.0257 0.0289
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.0769 0.0896
Loa Loa (eye worm) acyl carrier protein 0.0188 0.2276 0.2563
Onchocerca volvulus Peroxidasin homolog 0.0019 0.0058 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0063 0.0629 0.0629
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0086 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0345 0.0384
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0086 0.0064
Echinococcus granulosus peroxidasin 0.0032 0.0225 0.0395
Loa Loa (eye worm) hypothetical protein 0.0055 0.0524 0.0591
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0235 0.0296
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Mycobacterium ulcerans quinone oxidoreductase 0.0025 0.0136 0.0082
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0769 0.0896
Schistosoma mansoni ran 0.0021 0.0073 0.0128
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0103 0.1152 0.518
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0035 0.0257 0.0452
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0769 0.334
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0015 0.0002 0.0004
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0086 0.0064
Echinococcus granulosus contactin 0.0032 0.0225 0.0395
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0103 0.1152 0.2026
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0103 0.1152 0.518
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0409 0.5182 0.657
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0086 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0289 0.0508
Echinococcus multilocularis GPCR, family 2 0.0016 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Echinococcus multilocularis Immunoglobulin 0.0076 0.0803 0.1412
Mycobacterium ulcerans acyl carrier protein 0.0041 0.0345 0.0351
Onchocerca volvulus 0.0019 0.0058 0.0061
Echinococcus granulosus hemicentin 1 0.0032 0.0225 0.0395
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0323 0.4055 0.7129
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Mycobacterium ulcerans polyketide synthase MbtC 0.0103 0.1152 0.139
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0086 0.0098
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0289 0.0311
Schistosoma mansoni septate junction protein 0.0032 0.0225 0.0395
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0143 0.0651
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0025 0.0136 0.0115
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0073 0.0003
Plasmodium vivax acyl carrier protein, putative 0.0041 0.0345 0.2527
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Echinococcus granulosus expressed protein 0.0034 0.0246 0.0432
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Echinococcus multilocularis lachesin 0.0032 0.0225 0.0395
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0289 0.1602
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0524 0.0581
Mycobacterium ulcerans thioesterase TesA 0.0341 0.4285 0.5421
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0074 0.0769 0.0866
Schistosoma mansoni importin beta-1 0.0028 0.017 0.0299
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.017 0.0468
Leishmania major zinc binding dehydrogenase-like protein 0.0025 0.0136 0.0305
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0289 0.0508
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0016 0.0015 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0086 0.0051
Onchocerca volvulus Fatty acid synthase homolog 0.0738 0.9501 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.002 0.007 0.0079
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0073 0.0128
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0086 0.0123
Toxoplasma gondii acyl carrier protein ACP 0.0041 0.0345 0.0498
Brugia malayi beta-lactamase family protein 0.0037 0.0289 0.0289
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0025 0.0136 0.0082
Brugia malayi Alcohol dehydrogenase class III 0.0025 0.0136 0.0136
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0485 0.0562
Onchocerca volvulus Netrin receptor homolog 0.0019 0.0058 0.0061
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0025 0.0136 0.0471
Schistosoma mansoni serine/threonine protein kinase 0.002 0.007 0.0123
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.01 0.1117 0.1373
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0289 0.1038
Schistosoma mansoni cpg binding protein 0.0033 0.0239 0.042
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0289 0.1602
Loa Loa (eye worm) hypothetical protein 0.0108 0.1226 0.138
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0086 0.0064
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase otk 0.0032 0.0225 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0769 0.0769
Trypanosoma brucei oxidoreductase, putative 0.0025 0.0136 0.0305
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0026 0.0142 0.0249
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0524 0.4184
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0011 0.0011
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0086 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0025 0.0136 0.0239
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0025 0.0136 0.0065
Echinococcus granulosus low density lipoprotein receptor ldl 0.0015 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0404 0.5113 0.5113
Mycobacterium leprae Probable oxidireductase 0.0025 0.0136 0.0065
Brugia malayi Prion-like- 0.0019 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0235 0.078
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0225 0.0253
Brugia malayi protein unc-22 0.002 0.007 0.007
Onchocerca volvulus 0.0025 0.0136 0.0143
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0041 0.0345 0.1309
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0025 0.0136 0.0305
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0235 0.078
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0032 0.0225 0.0395
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0091 0.0103
Leishmania major nuclear receptor binding factor-like protein 0.0025 0.0136 0.0305
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.017 0.0178
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0086 0.0024
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0271 0.336 0.422
Onchocerca volvulus 0.0019 0.0058 0.0061
Brugia malayi Prion-like- 0.0019 0.0058 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0769 0.0896
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0025 0.0136 0.0082
Mycobacterium tuberculosis Hypothetical protein 0.0123 0.1423 0.1765
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0015 0.0002 0.0004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.0769 0.0896
Mycobacterium tuberculosis Conserved protein 0.0037 0.0289 0.0311
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0063 0.0629 0.0748
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.002
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0015 0.0027
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0404 0.5113 0.6498
Leishmania major hypothetical protein, conserved 0.0026 0.0142 0.0331
Mycobacterium ulcerans hypothetical protein 0.0074 0.0769 0.0896
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0003
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0435 0.5517 0.7006
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0265 0.3292 0.5872
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Echinococcus granulosus GPCR family 2 0.0016 0.0011 0.002
Mycobacterium ulcerans Type I modular polyketide synthase 0.0409 0.5182 0.6576
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0035 0.0257 0.0452
Leishmania major hypothetical protein, conserved 0.0037 0.0289 0.1038
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0059 0.0573 0.4635
Echinococcus granulosus importin subunit beta 1 0.0028 0.017 0.0299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0524 0.3787
Mycobacterium ulcerans polyketide synthase 0.0435 0.5517 0.7006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0025 0.0136 0.0116
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0025 0.0136 0.0305
Brugia malayi kettin 0.0019 0.0058 0.0058
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0025 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0299 0.3732 0.6562
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0524 0.4184
Mycobacterium ulcerans oxidoreductase FadB5 0.0025 0.0136 0.0082
Brugia malayi Phosphopantetheine attachment site family protein 0.0041 0.0345 0.0345
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0041 0.0345 0.0607
Brugia malayi RNA, U transporter 1 0.008 0.0849 0.0849
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0011 0.0013
Onchocerca volvulus Putative titin 0.0019 0.0058 0.0061
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0035 0.0257 0.0452
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0257 0.0884
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0129 0.1492 0.1813
Trypanosoma cruzi oxidoreductase, putative 0.0025 0.0136 0.0305
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0086 0.0151
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0035 0.0257 0.1365
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Echinococcus multilocularis peroxidasin 0.0032 0.0225 0.0395
Plasmodium vivax importin-beta 2, putative 0.0028 0.017 0.0903
Brugia malayi basement membrane proteoglycan precursor 0.0015 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0073 0.0034
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0025 0.0136 0.0305
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0025 0.0136 0.0115
Echinococcus granulosus roundabout 2 0.0108 0.1226 0.2155
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0141 0.1652 0.2059
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0002
Schistosoma mansoni alcohol dehydrogenase 0.0025 0.0136 0.0239
Brugia malayi Animal haem peroxidase family protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0289 0.0325
Echinococcus multilocularis neuroglian 0.0032 0.0225 0.0395
Loa Loa (eye worm) hypothetical protein 0.0055 0.0524 0.0591
Echinococcus granulosus titin 0.002 0.007 0.0123
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0225 0.0253
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0063 0.0627 0.0745
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.01 0.0207
Echinococcus multilocularis dnaJ subfamily B 0.0448 0.5688 1
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0015 0.0002 0.0004
Onchocerca volvulus Tyrosine kinase homolog 0.0605 0.7758 0.8165
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Loa Loa (eye worm) hypothetical protein 0.0229 0.2816 0.3172
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0329 0.4131 0.5215
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Echinococcus granulosus titin 0.002 0.007 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0019 0.0058 0.0101
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0103 0.1152 0.1152
Loa Loa (eye worm) fatty acid synthase 0.0404 0.5111 0.5755
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0294 0.3667 0.4644
Schistosoma mansoni ran 0.0021 0.0073 0.0128
Onchocerca volvulus 0.002 0.007 0.0073
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0032 0.0225 0.0395
Echinococcus multilocularis twitchin 0.002 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0074 0.0769 0.0866
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0435 0.5517 0.7006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0289 0.0311
Onchocerca volvulus 0.0019 0.0058 0.0061
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0019 0.0058 0.0058
Schistosoma mansoni titin 0.0019 0.0058 0.0101
Entamoeba histolytica hypothetical protein 0.0179 0.2157 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0289 0.1602
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0063 0.0629 0.0716
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0025 0.0136 0.0082
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0025 0.0136 0.0305
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0035 0.0257 0.0257
Schistosoma mansoni tyrosine kinase 0.0016 0.0015 0.0027
Schistosoma mansoni cell adhesion molecule 0.0032 0.0225 0.0395
Chlamydia trachomatis acyl carrier protein 0.0041 0.0345 0.2016
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0019 0.0058 0.0101
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0044 0.0385 0.0402
Entamoeba histolytica acyl-CoA synthetase, putative 0.0044 0.0385 0.1498
Leishmania major oxidoreductase, putative 0.0025 0.0136 0.0305
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0246 0.0246
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0769 0.088
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0323 0.4055 0.7129
Schistosoma mansoni ap endonuclease 0.0021 0.0073 0.0128
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0257 0.0884
Mycobacterium ulcerans short-chain dehydrogenase 0.0025 0.0136 0.0082
Loa Loa (eye worm) SRC-1 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0287
Loa Loa (eye worm) projectin 0.0019 0.0058 0.0065
Onchocerca volvulus 0.0019 0.0058 0.0061
Toxoplasma gondii quinone oxidoreductase, putative 0.0025 0.0136 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Schistosoma mansoni zinc binding dehydrogenase 0.0025 0.0136 0.0239
Entamoeba histolytica protein kinase, putative 0.0179 0.2157 1
Echinococcus multilocularis roundabout 2 0.0032 0.0225 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0225 0.0225
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0025 0.0136 0.0305
Mycobacterium ulcerans acyl carrier protein 0.0041 0.0345 0.0351
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0409 0.5182 0.6587
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0341 0.4285 0.5414
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0073 0.0082
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0063 0.0627 0.0698
Onchocerca volvulus 0.0037 0.0289 0.0304
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0063 0.0627 0.0745
Leishmania major GTP-binding protein, putative 0.0021 0.0073 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Schistosoma mansoni [ACP] S-malonyltransferase 0.0026 0.0142 0.0249
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0086 0.0064
Echinococcus multilocularis titin 0.0019 0.0058 0.0101
Mycobacterium ulcerans polyketide synthase Pks13 0.0612 0.7843 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0573 0.4635
Loa Loa (eye worm) one IG domain family member 0.0019 0.0058 0.0065
Onchocerca volvulus 0.0063 0.0629 0.0662
Brugia malayi Protein kinase domain containing protein 0.0023 0.0106 0.0106
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0103 0.1152 1
Schistosoma mansoni methyltransferase-related 0.0123 0.1423 0.2502
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0025 0.0136 0.0082
Loa Loa (eye worm) hypothetical protein 0.0074 0.0769 0.0866
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0011 0.0011
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0058 0.0101
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0086 0.0064
Schistosoma mansoni cell adhesion molecule 0.0019 0.0058 0.0101
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0225 0.0253
Mycobacterium leprae Probable polyketide synthase Pks1 0.0435 0.5517 0.7001
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0086 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0086 0.0097
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Onchocerca volvulus 0.0025 0.0136 0.0143
Echinococcus multilocularis titin 0.0019 0.0058 0.0101
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0025 0.0136 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0612 0.7843 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0409 0.5182 0.6576
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0289 0.0311
Schistosoma mansoni cell adhesion molecule 0.0019 0.0058 0.0101
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0025 0.0136 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0179 0.2157 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0235 0.078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Brugia malayi SRC-1 0.0016 0.0015 0.0015
Onchocerca volvulus 0.0019 0.0058 0.0061
Schistosoma mansoni titin 0.0032 0.0225 0.0395
Schistosoma mansoni tyrosine kinase 0.0323 0.4055 0.7129
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0246 0.1281
Echinococcus multilocularis geminin 0.0338 0.4252 0.7475
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0025 0.0136 0.0082
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0435 0.5517 0.7001
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0086 0.0017
Echinococcus granulosus dnaJ subfamily B 0.0448 0.5688 1
Entamoeba histolytica protein kinase, putative 0.0179 0.2157 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0136 0.0153
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0674 0.867 0.9763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0803 0.0803
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0409 0.5182 0.6576
Trichomonas vaginalis rotamase, putative 0.0033 0.0235 0.1204
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.0002
Loa Loa (eye worm) beta-lactamase 0.0037 0.0289 0.0325
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0019 0.0058 0.0101
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0086 0.0086
Leishmania major quinone oxidoreductase, putative 0.0025 0.0136 0.0305
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0015 0.0027
Onchocerca volvulus 0.0404 0.5113 0.5381
Leishmania major d-xylulose reductase, putative 0.0025 0.0136 0.0305
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0025 0.0136 0.0471
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0058 0.0065
Trypanosoma brucei oxidoreductase, putative 0.0025 0.0136 0.0305
Schistosoma mansoni rotamase 0.0034 0.0246 0.0432
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.0101
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0235 0.078
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0025 0.0136 0.0082
Echinococcus granulosus ubiquitin specific protease 41 0.0035 0.0257 0.0452
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0025 0.0136 0.0305
Echinococcus granulosus roundabout 2 0.0032 0.0225 0.0395
Trichomonas vaginalis importin beta-1, putative 0.0023 0.01 0.0207
Brugia malayi Leucine Rich Repeat family protein 0.0019 0.0058 0.0058
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0025 0.0136 0.0305
Echinococcus multilocularis ubiquitin specific protease 41 0.0035 0.0257 0.0452
Loa Loa (eye worm) hypothetical protein 0.0076 0.0803 0.0904
Trypanosoma cruzi acyl transferase-like protein 0.0026 0.0142 0.0331
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0612 0.7843 1
Treponema pallidum acyl carrier protein 0.0041 0.0345 1
Trypanosoma cruzi acyl transferase-like protein, putative 0.0026 0.0142 0.0331
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0025 0.0136 0.0153
Schistosoma mansoni titin 0.002 0.007 0.0123
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0019 0.0058 0.0101
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0769 0.0896
Leishmania major hypothetical protein, conserved 0.0123 0.1423 0.6477
Trypanosoma cruzi oxidoreductase, putative 0.0025 0.0136 0.0305
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0063 0.0629 0.0748
Schistosoma mansoni hypothetical protein 0.0448 0.5688 1
Schistosoma mansoni cell adhesion molecule 0.0032 0.0225 0.0395
Loa Loa (eye worm) oxidoreductase 0.0022 0.0086 0.0097
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0103 0.1152 0.2026
Brugia malayi Tyrosine-protein kinase abl-1 0.0016 0.0015 0.0015
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0086 0.0051
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0769 0.334
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0073
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0289 0.0311
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0086 0.0064
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0035 0.0257 0.0884
Mycobacterium tuberculosis Possible dehydrogenase 0.0025 0.0136 0.0115
Loa Loa (eye worm) animal heme peroxidase 0.0019 0.0058 0.0065
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0233 0.2861 0.361
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0086 0.0017
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0086 0.0024
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0025 0.0136 0.0471
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0033 0.0237 0.0267
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0065
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0032 0.0225 0.0395
Echinococcus granulosus cpg binding protein 0.0033 0.0239 0.042

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 52.79 % Inhibition of cell proliferation of human U251 cells assessed as cell viability at 100 uM after 72 hrs by sulforhodamine B assay ChEMBL. 25442304

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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