Detailed information for compound 1825524

Basic information

Technical information
  • TDR Targets ID: 1825524
  • Name: (E)-N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phe nylprop-2-enamide
  • MW: 335.443 | Formula: C21H25N3O
  • H donors: 1 H acceptors: 1 LogP: 3.48 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)c1ccc(cc1)NC(=O)/C=C/c1ccccc1
  • InChi: 1S/C21H25N3O/c1-2-23-14-16-24(17-15-23)20-11-9-19(10-12-20)22-21(25)13-8-18-6-4-3-5-7-18/h3-13H,2,14-17H2,1H3,(H,22,25)/b13-8+
  • InChiKey: QSYHLGFWSIUSHK-MDWZMJQESA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phenylprop-2-enamide
  • N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phenyl-prop-2-enamide
  • (E)-N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phenyl-prop-2-enamide
  • N-[4-(4-ethyl-1-piperazinyl)phenyl]-3-phenylprop-2-enamide
  • (E)-N-[4-(4-ethyl-1-piperazinyl)phenyl]-3-phenylprop-2-enamide
  • (E)-N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phenyl-acrylamide
  • N-[4-(4-ethylpiperazin-1-yl)phenyl]-3-phenyl-acrylamide
  • ST001046
  • TimTec1_000063

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable lipase LipD 0.0066 0.0387 0.1336
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0033 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.1222 0.7753
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0228 0.0228
Onchocerca volvulus 0.0134 0.0874 0.1078
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0094 0.0589 0.0589
Echinococcus granulosus carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) ABC transporter 0.0016 0.0037 0.0037
Entamoeba histolytica carbonic anhydrase, putative 0.0141 0.0923 0.5904
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0246 0.1668 0.1668
Onchocerca volvulus Glutaminyl cyclase homolog 0.1152 0.8096 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0016 0.0037 0.0404
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0028 0.0118 0.0118
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0066 0.0066
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0585 0.0585
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0521 0.1799
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0074 0.0074
Trypanosoma cruzi MFS transporter, putative 0.0022 0.0076 0.0076
Schistosoma mansoni metabotropic glutamate receptor 0.0291 0.1985 0.1985
Echinococcus multilocularis Regulator of G protein signaling 20 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0253 0.1715 0.1715
Echinococcus granulosus carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0053
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0187 0.1245 0.1245
Loa Loa (eye worm) hypothetical protein 0.0057 0.0328 0.0328
Onchocerca volvulus 0.002 0.0066 0.008
Loa Loa (eye worm) 6-phosphofructokinase 0.0085 0.0525 0.0525
Schistosoma mansoni nuclear hormone receptor 0.002 0.0066 0.0066
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.002
Schistosoma mansoni axis inhibition protein axin 0.0015 0.0028 0.0028
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0074 0.0074
Plasmodium falciparum carbonic anhydrase 0.0651 0.4539 1
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0028 0.0118 0.0118
Echinococcus granulosus jumonji domain containing protein 0.004 0.0203 0.0203
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0077 0.0467 0.0467
Plasmodium vivax ABC transporter B family member 5, putative 0.0016 0.0037 0.0217
Leishmania major T-complex protein 1, beta subunit, putative 0.0022 0.0079 0.0079
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0013 0.0013
Echinococcus multilocularis axis inhibition protein axin 0.0015 0.0028 0.0028
Echinococcus granulosus histone acetyltransferase KAT2B 0.0121 0.0779 0.0779
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0228 0.0228
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0525 0.3328
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0066 0.0387 0.1336
Echinococcus multilocularis regulator of G protein signaling 3 0.0015 0.0028 0.0028
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0186 0.0186
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0183 0.1222 0.1222
Trichomonas vaginalis abcb9, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) histone methyltransferase 0.0016 0.0032 0.0032
Giardia lamblia ABC transporter, putative 0.0047 0.0254 0.1576
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0049 0.0049
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0085 0.0525 0.5692
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Echinococcus granulosus ATP binding cassette sub family B 0.0016 0.0037 0.0037
Brugia malayi Regulator of G protein signaling domain containing protein 0.0015 0.0028 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0228 0.0228
Brugia malayi SPARC precursor 0.0015 0.0027 0.0027
Schistosoma mansoni sodium/solute symporter 0.0032 0.0147 0.0147
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0187 0.1245 0.1245
Plasmodium falciparum phd finger protein, putative 0.0029 0.0124 0.0271
Onchocerca volvulus 0.0057 0.0328 0.0403
Entamoeba histolytica P-glycoprotein-1 0.0028 0.0118 0.0605
Echinococcus granulosus cpg binding protein 0.005 0.0275 0.0275
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0228 0.0228
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0076 0.0076
Trypanosoma brucei carbonic anhydrase-like protein 0.1421 1 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0015 0.0026 0.541
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0056 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0083 0.0083
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0019 0.0053 0.0434
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0032 0.0147 0.0147
Echinococcus multilocularis peregrin 0.0032 0.0146 0.0146
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0014 0.002 0.0162
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Brugia malayi GH02984p 0.0288 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0124 0.0124
Echinococcus granulosus Smad4 0.0013 0.0013 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0124 0.0738
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0037 0.0181 0.0398
Onchocerca volvulus 0.002 0.0066 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0259 0.2117
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0229 0.1546 1
Treponema pallidum fructose-bisphosphate aldolase 0.0229 0.1546 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Trichomonas vaginalis taga, putative 0.0028 0.0118 0.074
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0023 0.0085 0.6844
Echinococcus granulosus tyrosine kinase 0.0056 0.0319 0.0319
Echinococcus granulosus beta-adrenergic receptor kinase 0.0015 0.0028 0.0028
Mycobacterium tuberculosis Conserved protein 0.0066 0.0387 0.1336
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor 0.002 0.0066 0.0066
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Echinococcus granulosus ATP binding cassette sub family B 0.0016 0.0033 0.0033
Brugia malayi nuclear hormone receptor 0.002 0.0066 0.0066
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0066 0.0387 0.0387
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0228 0.0228
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0228 0.0228
Echinococcus multilocularis 0.0016 0.0037 0.0037
Brugia malayi glutathione reductase 0.0037 0.0184 0.0184
Echinococcus multilocularis isocitrate dehydrogenase 0.0027 0.011 0.011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.011 0.011
Schistosoma mansoni single-minded 0.0038 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0027 0.0114 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0066 0.0391 0.0391
Brugia malayi ABC transporter 0.0016 0.0033 0.0033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0066 0.0066
Brugia malayi FXNA 0.0183 0.1222 0.1222
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0037 0.0082
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0016 0.0037 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0023 0.0085 0.0386
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Entamoeba histolytica multidrug resistance protein, putative 0.0047 0.0254 0.1501
Onchocerca volvulus 0.0079 0.0484 0.0597
Leishmania major cytochrome p450-like protein 0.0018 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0228 0.0228
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0228 0.0228
Schistosoma mansoni 6-phosphofructokinase 0.0085 0.0525 0.0525
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.1152 0.8096 0.8096
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0016 0.0033 0.0033
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0015 0.0027 0.006
Toxoplasma gondii ABC transporter, putative 0.0016 0.0037 0.0082
Toxoplasma gondii ABC transporter family protein 0.0016 0.0037 0.0082
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0048 0.0259 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0228 0.0228
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0124 0.0273
Leishmania major carbonic anhydrase-like protein 0.1421 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0079 0.0484 0.0484
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0053 0.0575
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Brugia malayi ABC transporter family protein 0.0016 0.0037 0.0037
Echinococcus multilocularis ATP binding cassette sub family B 0.0016 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0028
Onchocerca volvulus 0.0233 0.1576 0.1945
Toxoplasma gondii aldehyde dehydrogenase 0.0048 0.0259 0.057
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0006 0.0006
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0183 0.1222 0.1222
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.011 0.011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0014 0.002 0.0068
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0112 0.0715 0.7744
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0186 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0228 0.0228
Brugia malayi MH1 domain containing protein 0.0013 0.0013 0.0013
Plasmodium falciparum multidrug resistance protein 1 0.0028 0.0118 0.0257
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0083
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0541 0.3757 0.3757
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0186 0.0186
Loa Loa (eye worm) CYP4Cod1 0.0018 0.0049 0.0049
Echinococcus multilocularis nmda type glutamate receptor 0.0056 0.0319 0.0319
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0066 0.0066
Echinococcus multilocularis regulator of G protein signaling 3 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis dnaJ subfamily B 0.0671 0.4684 0.4684
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0015 0.0026 0.0212
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0027 0.011 0.011
Echinococcus granulosus transient receptor potential gamma protein 0.0253 0.1715 0.1715
Schistosoma mansoni lamin 0.0021 0.0071 0.0071
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.1152 0.8096 0.8096
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0066 0.0066
Brugia malayi jmjC domain containing protein 0.0094 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0083
Entamoeba histolytica P-glycoprotein-2, putative 0.0028 0.0118 0.0605
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0049 0.0049
Brugia malayi ABC transporter transmembrane region family protein 0.0047 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.034 0.034
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0057 0.0328 0.0328
Brugia malayi Bromodomain containing protein 0.0032 0.0146 0.0146
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) hypothetical protein 0.0735 0.5134 0.5134
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0016 0.0037 0.0129
Brugia malayi beta-lactamase family protein 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0288 0.1963 0.1963
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Echinococcus multilocularis geminin 0.0392 0.2703 0.2703
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0012 0.0012
Giardia lamblia PHD finger protein 15 0.0029 0.0124 0.0728
Loa Loa (eye worm) hypothetical protein 0.0057 0.0328 0.0328
Trypanosoma brucei glutaminyl cyclase, putative 0.0183 0.1222 0.1222
Echinococcus granulosus geminin 0.0392 0.2703 0.2703
Schistosoma mansoni aldehyde dehydrogenase 0.0048 0.0259 0.0259
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.0118 0.074
Brugia malayi conserved hypotetical protein 0.002 0.0066 0.0066
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0228 0.0228
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0027 0.011 0.011
Toxoplasma gondii hypothetical protein 0.0651 0.4539 1
Echinococcus granulosus multidrug resistance associated protein 7 0.0047 0.0254 0.0254
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1421 1 1
Plasmodium falciparum acyl-CoA synthetase 0.0014 0.002 0.0041
Onchocerca volvulus 0.0022 0.0076 0.0093
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1421 1 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0037 0.0181 0.114
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0015 0.0027 0.006
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0027 0.011 0.0241
Schistosoma mansoni cpg binding protein 0.005 0.0275 0.0275
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0076 0.0093
Entamoeba histolytica hypothetical protein 0.0056 0.0319 0.1932
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0053 0.0434
Loa Loa (eye worm) hypothetical protein 0.0021 0.0068 0.0068
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0387 0.0387
Brugia malayi metabotropic glutamate receptor type 2 0.0291 0.1985 0.1985
Entamoeba histolytica hypothetical protein 0.0015 0.0028 0.0013
Schistosoma mansoni hypothetical protein 0.0392 0.2703 0.2703
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0183 0.1222 0.1222
Onchocerca volvulus 0.0021 0.0071 0.0087
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0066 0.0066
Brugia malayi exodeoxyribonuclease III family protein 0.0015 0.0026 0.0026
Brugia malayi RE40412p 0.0011 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0228 0.0228
Leishmania major carbonic anhydrase family protein, putative 0.0141 0.0923 0.0923
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0074 0.0074
Loa Loa (eye worm) ABC transporter 0.0016 0.0037 0.0037
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.1152 0.8096 0.8096
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0028 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0066 0.0066
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0001
Entamoeba histolytica P-glycoprotein 5, putative 0.0016 0.0033 0.0049
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0203 0.0203
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0246 0.1668 0.1668
Trypanosoma cruzi multidrug resistance protein E, putative 0.0047 0.0254 0.0254
Loa Loa (eye worm) multidrug resistance protein 3 0.0028 0.0118 0.0118
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0037 0.0082
Echinococcus multilocularis lamin dm0 0.0021 0.0071 0.0071
Echinococcus granulosus 6 phosphofructokinase 0.0085 0.0525 0.0525
Echinococcus granulosus single minded 2 0.0028 0.0121 0.0121
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0319 0.0319
Brugia malayi nuclear receptor RXR 0.0023 0.0083 0.0083
Echinococcus granulosus sodium:glucose cotransporter 0.0032 0.0147 0.0147
Brugia malayi MH2 domain containing protein 0.0013 0.0013 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0083 0.0083
Schistosoma mansoni inositol transporter 0.0032 0.0147 0.0147
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0012 0.0012
Echinococcus multilocularis multidrug resistance protein 1 0.0028 0.0118 0.0118
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0023 0.0085 0.0528
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0079 0.0079
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0183 0.1222 0.4221
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0066 0.0391 0.0391
Entamoeba histolytica P-glycoprotein-2, putative 0.0016 0.0033 0.0049
Brugia malayi PHD-finger family protein 0.0012 0.0007 0.0007
Onchocerca volvulus 0.0019 0.0053 0.0064
Schistosoma mansoni multidrug resistance protein 0.0028 0.0118 0.0118
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0015 0.0028 0.0028
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0525 0.3287
Onchocerca volvulus 0.0134 0.0874 0.1078
Echinococcus granulosus beta LACTamase domain containing family member 0.0066 0.0387 0.0387
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0015 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0159 0.1048 0.1048
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0184 0.0184
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0019 0.0053 0.0434
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0076 0.0076
Schistosoma mansoni smad1 5 8 and 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0134 0.0874 0.0874
Echinococcus multilocularis transient receptor potential ion channel A 0.0244 0.1655 0.1655
Onchocerca volvulus Fxna peptidase homolog 0.0183 0.1222 0.1508
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0001 0.0001
Echinococcus granulosus smad 0.0013 0.0013 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0246 0.1668 0.1668
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0651 0.4539 0.4539
Brugia malayi hypothetical protein 0.0023 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0066 0.0391 0.0391
Trypanosoma cruzi glutaminyl cyclase, putative 0.0183 0.1222 0.1222
Trichomonas vaginalis penicillin-binding protein, putative 0.0066 0.0387 0.2448
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0246 0.1668 0.1668
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0012 0.007
Brugia malayi Peptidase family M28 containing protein 0.1152 0.8096 0.8096
Echinococcus multilocularis musashi 0.0021 0.0071 0.0071
Echinococcus granulosus nmda type glutamate receptor 0.0056 0.0319 0.0319
Onchocerca volvulus 0.0022 0.0076 0.0093
Giardia lamblia Multidrug resistance-associated protein 1 0.0047 0.0254 0.1576
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0228 0.0228
Mycobacterium ulcerans lipase LipD 0.0066 0.0387 0.3165
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0101
Brugia malayi ABC transporter family protein 0.0016 0.0037 0.0037
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0015 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Echinococcus multilocularis axis inhibition protein axin 0.0015 0.0028 0.0028
Brugia malayi ABC transporter 0.0016 0.0037 0.0037
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0022 0.0079 0.0469
Schistosoma mansoni hypothetical protein 0.0041 0.0209 0.0209
Onchocerca volvulus 0.0134 0.0874 0.1078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Schistosoma mansoni multidrug resistance protein 0.0047 0.0254 0.0254
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0101 0.0638 0.0638
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0228 0.0228
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0026 0.0054
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0001 0.0001
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0076 0.0093
Leishmania major extracellular receptor, putative 0.0056 0.0319 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0228 0.0228
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0134 0.0874 0.0874
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0026 0.0026
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0023 0.0085 0.0186
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Mycobacterium tuberculosis Probable hydrolase 0.0066 0.0387 0.1336
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0525 0.3328
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0521 0.1799
Echinococcus granulosus TRP transient receptor potential channel 0.0094 0.0589 0.0589
Brugia malayi ecdysteroid receptor 0.0043 0.0228 0.0228
Schistosoma mansoni transient receptor potential channel 0.0253 0.1715 0.1715
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0183 0.1222 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0015 0.0027 0.0027
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0525 0.3287
Echinococcus multilocularis solute carrier family 5 0.0032 0.0147 0.0147
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0023 0.0085 0.047
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0028 0.0028
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0134 0.0874 0.0874
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0228 0.0228
Schistosoma mansoni coup transcription factor 0.0043 0.0228 0.0228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0053 0.0183
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0016 0.0033 0.0033
Brugia malayi RE40412p 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0183 0.1222 0.1222
Echinococcus granulosus intermediate filament protein 0.0021 0.0071 0.0071
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0015 0.0028 0.0028
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Echinococcus granulosus multidrug resistance associated protein 1 0.0047 0.0254 0.0254
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1576 1
Onchocerca volvulus 0.0066 0.0387 0.0476
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0114 0.0114
Echinococcus granulosus carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.1376 0.1376
Toxoplasma gondii protease inhibitor PI2 0.0015 0.0027 0.006
Schistosoma mansoni smad1 5 8 and 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Brugia malayi bHLH-PAS transcription factor 0.0028 0.0121 0.0121
Brugia malayi steroid hormone receptor 0.0043 0.0228 0.0228
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0079 0.0484 0.0484
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0183 0.1222 0.1222
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0525 0.3328
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0183 0.1222 0.7753
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0077 0.0467 0.0467
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Echinococcus multilocularis Smad4 0.0013 0.0013 0.0013
Echinococcus multilocularis expressed protein 0.0015 0.0027 0.0027
Echinococcus multilocularis tyrosine kinase 0.0056 0.0319 0.0319
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0023 0.0085 0.0184
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0012 0.0101
Brugia malayi leucyl aminopeptidase 0.0183 0.1222 0.1222
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0032 0.0147 0.0147
Brugia malayi Receptor family ligand binding region containing protein 0.0153 0.1007 0.1007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0588 0.203
Echinococcus multilocularis carbonic anhydrase 0.0651 0.4539 0.4539
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0016 0.0037 0.0305
Onchocerca volvulus 0.0056 0.0319 0.0393
Echinococcus multilocularis multidrug resistance associated protein 7 0.0047 0.0254 0.0254
Echinococcus multilocularis follistatin 0.0015 0.0027 0.0027
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0015 0.0026 0.0026
Echinococcus multilocularis multidrug resistance associated protein 1 0.0047 0.0254 0.0254
Brugia malayi prostaglandin transporter 0.0022 0.0076 0.0076
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0319 0.0319
Giardia lamblia Multidrug resistance-associated protein 1 0.0046 0.025 0.1549
Echinococcus granulosus agrin 0.0015 0.0027 0.0027
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0008 0.0015
Schistosoma mansoni high-affinity choline transporter 0.0288 0.1963 0.1963
Trypanosoma brucei multidrug resistance protein E 0.0047 0.0254 0.0254
Echinococcus multilocularis carbonic anhydrase II 0.1421 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0014 0.005
Brugia malayi hypothetical protein 0.0023 0.0083 0.0083
Loa Loa (eye worm) multidrug resistance-associated protein 0.0031 0.0142 0.0142
Echinococcus multilocularis GPCR, family 3, C terminal 0.0097 0.0609 0.0609
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1421 1 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0651 0.4539 0.4539
Schistosoma mansoni lamin 0.0021 0.0071 0.0071
Echinococcus granulosus expressed protein 0.0292 0.1996 0.1996
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0016 0.0033 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0387 0.0387
Brugia malayi Metabotropic glutamate receptor precursor. 0.0597 0.4156 0.4156
Trichomonas vaginalis D-aminoacylase, putative 0.0066 0.0387 0.2448
Echinococcus multilocularis regulator of G protein signaling 0.0015 0.0028 0.0028
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0015 0.0026 0.0026
Brugia malayi 6-phosphofructokinase 0.0085 0.0525 0.0525
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0066 0.0387 0.0387
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0076 0.0076
Brugia malayi 6-phosphofructokinase 0.0086 0.0529 0.0529
Entamoeba histolytica hypothetical protein 0.0058 0.0333 0.2018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0136 0.03
Onchocerca volvulus 0.0056 0.0319 0.0393
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0228 0.0228
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0016 0.0037 0.0037
Leishmania major ABC-thiol transporter 0.0047 0.0254 0.0254
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0012 0.0027
Onchocerca volvulus 0.0047 0.0256 0.0315
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0022 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi intermediate filament protein 0.0021 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0292 0.1996 0.1996
Echinococcus multilocularis multidrug resistance protein 1 0.0028 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0142 0.0928 0.0928
Entamoeba histolytica P-glycoprotein 6, putative 0.0016 0.0037 0.0075
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0228 0.0228
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0184 0.0184
Entamoeba histolytica hypothetical protein 0.0015 0.0028 0.0013
Loa Loa (eye worm) hypothetical protein 0.0066 0.0391 0.0391
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0074 0.0074
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0228 0.0228
Brugia malayi Calcitonin receptor-like protein seb-1 0.0208 0.1394 0.1394
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0136 0.0136
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0028 0.0118 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0053 0.0053
Echinococcus multilocularis metabotropic glutamate receptor 2 0.05 0.3468 0.3468
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0124 0.0804 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Schistosoma mansoni tyrosine kinase 0.0056 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.0136
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0028 0.0118 0.0118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0014 0.005
Mycobacterium ulcerans esterase/lipase LipP 0.0066 0.0387 0.3165
Brugia malayi PAS domain containing protein 0.0038 0.0192 0.0192
Plasmodium vivax multidrug resistance protein 2, putative 0.0016 0.0037 0.0217
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1421 1 1
Plasmodium falciparum T-complex protein 1 subunit beta 0.0022 0.0079 0.0172
Schistosoma mansoni 6-phosphofructokinase 0.0085 0.0525 0.0525
Schistosoma mansoni aryl hydrocarbon receptor 0.0038 0.0192 0.0192
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0228 0.028
Brugia malayi hypothetical protein 0.002 0.0066 0.0066
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0037 0.0082
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0016 0.0037 0.0037
Toxoplasma gondii ABC1 family protein 0.0066 0.0387 0.0852
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0228 0.0228
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0001 0.0001
Loa Loa (eye worm) agrin synaptic family protein 0.0015 0.0027 0.0027
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0022 0.0076 0.0076
Echinococcus granulosus mixed lineage leukemia protein mll 0.0013 0.0012 0.0012
Schistosoma mansoni cpg binding protein 0.0047 0.0256 0.0256
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0076 0.0093
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0012 0.0101
Onchocerca volvulus Fxna peptidase homolog 0.0183 0.1222 0.1508
Brugia malayi ABC transporter transmembrane region family protein 0.0016 0.0033 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0053 0.0053
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0053 0.0575
Leishmania major p-glycoprotein 0.0028 0.0118 0.0118
Echinococcus multilocularis high affinity choline transporter 1 0.0288 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0057 0.0328 0.0328
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0016 0.0037 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0001 0.0001
Echinococcus multilocularis glutamate receptor 2 0.0056 0.0319 0.0319
Entamoeba histolytica P-glycoprotein 5, putative 0.0028 0.0118 0.0605
Giardia lamblia MRP-like ABC transporter 0.0047 0.0254 0.1576
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0419 0.2895 1
Brugia malayi hypothetical protein 0.0022 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0077 0.0467 0.0467
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0228 0.0228
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0053 0.0434
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0183 0.1222 0.1222
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Echinococcus granulosus histone acetyltransferase KAT2B 0.0037 0.0181 0.0181
Schistosoma mansoni multidrug resistance protein 0.0047 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0183 0.1222 0.1222
Schistosoma mansoni agrin 0.0015 0.0027 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0066 0.0066
Echinococcus granulosus high affinity choline transporter 1 0.0288 0.1963 0.1963
Entamoeba histolytica hypothetical protein 0.0047 0.0254 0.1501
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0083 0.0083
Echinococcus granulosus dnaJ subfamily B 0.0671 0.4684 0.4684
Echinococcus granulosus lamin dm0 0.0021 0.0071 0.0071
Echinococcus multilocularis 6 phosphofructokinase 0.0085 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0028
Toxoplasma gondii zinc finger cdgsh type protein 0.0011 0.0001 0.0003
Onchocerca volvulus 0.0028 0.0121 0.0149
Echinococcus multilocularis short transient receptor potential channel 6 0.0167 0.1108 0.1108
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0083 0.0083
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0228 0.0228
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0521 0.5642
Brugia malayi A-kinase anchor protein 10, precursor 0.0015 0.0028 0.0028
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0028 0.0118 0.0118
Plasmodium falciparum ABC transporter B family member 7, putative 0.0016 0.0037 0.008
Loa Loa (eye worm) Smad1 0.0013 0.0013 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.0058 0.0333 0.0333
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Schistosoma mansoni smdr2 0.0028 0.0118 0.0118
Onchocerca volvulus 0.0134 0.0874 0.1078
Toxoplasma gondii phosphofructokinase PFKII 0.0023 0.0085 0.0186
Echinococcus granulosus short transient receptor potential channel 6 0.0167 0.1108 0.1108
Loa Loa (eye worm) leucyl aminopeptidase 0.0183 0.1222 0.1222
Loa Loa (eye worm) intermediate filament protein 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0254 0.0254
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0037 0.0181 0.114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0228 0.0228
Echinococcus multilocularis smad 0.0013 0.0013 0.0013
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0016 0.0037 0.0082
Schistosoma mansoni smad 0.0013 0.0013 0.0013
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0028 0.0118 0.026
Schistosoma mansoni transient receptor potential channel 0.0167 0.1108 0.1108
Entamoeba histolytica hypothetical protein 0.0015 0.0028 0.0013
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0012 0.0012
Plasmodium falciparum ABC transporter B family member 6, putative 0.0016 0.0037 0.008
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0016 0.0037 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0037 0.0181 0.0398
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0014 0.002 0.0701
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0001 0.0001
Plasmodium falciparum ABC transporter B family member 4, putative 0.0016 0.0037 0.008
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0319 0.0319
Leishmania major ATP-dependent phosphofructokinase 0.0085 0.0525 0.0525
Entamoeba histolytica hypothetical protein 0.0058 0.0333 0.2018
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0167 0.0167
Entamoeba histolytica hypothetical protein 0.0058 0.0333 0.2018
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0032 0.0147 0.0147
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1421 1 1
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0022 0.0076 0.0076
Schistosoma mansoni nuclear receptor 0.002 0.0066 0.0066
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0228 0.028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0651 0.4539 0.4539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0012 0.0012
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.0141 0.0923 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.0032 0.0147 0.0147
Plasmodium falciparum thioredoxin reductase 0.0037 0.0184 0.0403
Mycobacterium leprae Probable lipase LipE 0.0066 0.0387 0.4191
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0033 0.0203
Trypanosoma brucei p-glycoprotein 0.0047 0.0254 0.0254
Schistosoma mansoni smdr1 0.0016 0.0037 0.0037
Echinococcus multilocularis cpg binding protein 0.005 0.0275 0.0275
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) hypothetical protein 0.0022 0.0074 0.0074
Entamoeba histolytica P-glycoprotein-2 0.0028 0.0118 0.0605
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0112 0.0715 0.2469
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0015 0.0026 0.0088
Loa Loa (eye worm) hypothetical protein 0.0029 0.0124 0.0124
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0047 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0012
Brugia malayi ABC transporter family protein 0.0028 0.0118 0.0118
Trichomonas vaginalis ABC transporter, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0074 0.0074
Toxoplasma gondii t-complex protein beta subunit 0.0022 0.0079 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Schistosoma mansoni multidrug resistance protein 0.0028 0.0118 0.0118
Schistosoma mansoni inositol transporter 0.0032 0.0147 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0066 0.0387 0.2448
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0259 0.2117
Mycobacterium ulcerans hypothetical protein 0.0066 0.0387 0.3165
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0037 0.0181 0.1079
Onchocerca volvulus 0.0066 0.0387 0.0476
Onchocerca volvulus 0.0134 0.0874 0.1078
Loa Loa (eye worm) hypothetical protein 0.0077 0.0467 0.0467
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0016 0.0037 0.0305
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0028 0.0118 0.0118
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0048 0.0259 0.0259
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0228 0.0228
Echinococcus granulosus peregrin 0.0032 0.0146 0.0146
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0047 0.0254 0.0254
Loa Loa (eye worm) 6-phosphofructokinase 0.0085 0.0525 0.0525
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0112 0.0715 0.5849
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0066 0.0387 0.3165
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0047 0.0254 0.0254
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.002
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0077 0.0467 0.0467
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0011 0.0001 0.0001
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0016 0.0037 0.0037
Echinococcus multilocularis lamin 0.0021 0.0071 0.0071
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Brugia malayi Cytochrome P450 family protein 0.0018 0.0049 0.0049
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0049 0.0049
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0056 0.0319 0.0319
Onchocerca volvulus 0.0022 0.0076 0.0093
Brugia malayi ecdysone receptor 0.002 0.0066 0.0066
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0047 0.0254 0.0254
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0013 0.0013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0521 0.1799
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0066 0.0387 0.0387
Brugia malayi P-glycoprotein-like protein 0.0016 0.0037 0.0037
Echinococcus granulosus transient receptor potential ion channel A 0.0244 0.1655 0.1655
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0016 0.0037 0.0037
Leishmania major glutaminyl cyclase, putative 0.0183 0.1222 0.1222
Brugia malayi phosphofructokinase 0.0085 0.0525 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0208 0.1394 0.1394
Loa Loa (eye worm) glutathione reductase 0.0037 0.0184 0.0184
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0079 0.0079
Loa Loa (eye worm) RGS-3 protein 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Toxoplasma gondii hypothetical protein 0.0183 0.1222 0.2692
Schistosoma mansoni hypothetical protein 0.0651 0.4539 0.4539
Schistosoma mansoni multidrug resistance protein 0.0016 0.0037 0.0037
Brugia malayi nuclear hormone receptor 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0083
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0013 0.0012 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0246 0.1668 0.1668
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0056 0.0319 0.0319
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0014 0.005
Schistosoma mansoni carbonic anhydrase-related 0.0651 0.4539 0.4539
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0198 0.1325 0.1325
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0028 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0078 0.0078
Mycobacterium leprae conserved hypothetical protein 0.0066 0.0387 0.4191
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0525 0.3328
Schistosoma mansoni hypothetical protein 0.0066 0.0387 0.0387
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0186 0.0186
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.0118 0.074
Brugia malayi nicalin 0.0183 0.1222 0.1222
Brugia malayi Sodium:solute symporter family protein 0.0032 0.0147 0.0147
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0066 0.0066
Loa Loa (eye worm) glutamate receptor 0.0235 0.1587 0.1587
Brugia malayi Nuclear hormone receptor E75 0.002 0.0066 0.0066
Loa Loa (eye worm) carbonic anhydrase 3 0.1421 1 1
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0026 0.0156
Schistosoma mansoni ap endonuclease 0.0015 0.0026 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Echinococcus granulosus Regulator of G protein signaling 20 0.0015 0.0028 0.0028
Entamoeba histolytica ATP-binding cassette protein, putative 0.0047 0.0254 0.1501
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.0118 0.074
Plasmodium vivax ABC transporter B family member 3, putative 0.0016 0.0037 0.0217
Schistosoma mansoni transient receptor potential channel 0.0167 0.1108 0.1108
Trichomonas vaginalis penicillin-binding protein, putative 0.0066 0.0387 0.2448
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0022 0.0079 0.0079
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0012 0.0025
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0134 0.0874 0.1078
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0228 0.0228
Loa Loa (eye worm) CXXC zinc finger family protein 0.0047 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0142 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Plasmodium vivax multidrug resistance protein 1, putative 0.0028 0.0118 0.07
Brugia malayi Isocitrate dehydrogenase 0.0027 0.011 0.011
Loa Loa (eye worm) ABC transporter 0.0016 0.0037 0.0037
Trichomonas vaginalis chaperonin, putative 0.0022 0.0079 0.0495
Toxoplasma gondii histone lysine methyltransferase SET1 0.0093 0.0584 0.1287
Echinococcus granulosus carbonic anhydrase II 0.1421 1 1
Trypanosoma brucei cytochrome P450, putative 0.0018 0.0049 0.0049
Plasmodium falciparum ABC transporter B family member 5, putative 0.0016 0.0037 0.008
Brugia malayi hypothetical protein 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0114 0.0114
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0001 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0001 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0588 0.6366
Onchocerca volvulus 0.0022 0.0076 0.0093
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0066 0.0066
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0074 0.0074
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0027 0.011 0.011
Echinococcus granulosus atrial natriuretic peptide receptor 0.0056 0.0319 0.0319
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0016 0.0033 0.0136
Onchocerca volvulus 0.0183 0.1222 0.1508
Echinococcus granulosus glutamate receptor 2 0.0056 0.0319 0.0319
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0679 0.4736 0.4736
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0521 0.1799
Echinococcus granulosus conserved hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0022 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Leishmania major hypothetical protein, conserved 0.0066 0.0387 0.0387
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0037 0.0082
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0001 0.0001
Leishmania major trypanothione reductase 0.0037 0.0184 0.0184
Brugia malayi nuclear receptor NHR-88 0.002 0.0066 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0053 0.0053
Echinococcus multilocularis carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) hypothetical protein 0.0132 0.0857 0.0857
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0011 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0246 0.1668 0.1668
Plasmodium vivax glutathione reductase, putative 0.0037 0.0184 0.1099
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0032 0.0032
Loa Loa (eye worm) T-complex protein 1 0.0022 0.0079 0.0079
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0053 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0228 0.0228
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0011 0.0001 0.0003
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0074 0.0074
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0056 0.0319 0.0319
Brugia malayi ABC transporter transmembrane region family protein 0.0016 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0056 0.0319 0.0319
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0012 0.007
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0028 0.0118 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0228 0.0228
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0228 0.0228
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0588 0.203
Loa Loa (eye worm) hypothetical protein 0.0651 0.4539 0.4539
Mycobacterium ulcerans beta-lactamase 0.0066 0.0387 0.3165
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0651 0.4539 0.4539
Loa Loa (eye worm) transcription factor SMAD2 0.0189 0.1263 0.1263
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0079 0.0079
Toxoplasma gondii peptidase, M28 family protein 0.0183 0.1222 0.2692
Brugia malayi regulator of G-protein signaling rgs-7 0.0015 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0354 0.2243
Brugia malayi LBP/BPI 0.0057 0.0328 0.0328
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0027 0.011 0.011
Leishmania major protein kinase, putative 0.0013 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0387 0.0387
Echinococcus granulosus receptor type guanylyl cyclase 0.0056 0.0319 0.0319
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0066 0.0066
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0074 0.0074
Echinococcus granulosus axis inhibition protein axin 0.0015 0.0028 0.0028
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0066 0.0066
Plasmodium falciparum histone acetyltransferase GCN5 0.0034 0.0159 0.0348
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0032 0.0147 0.0323
Echinococcus granulosus GPCR family 3 C terminal 0.0097 0.0609 0.0609
Plasmodium falciparum multidrug resistance protein 2 0.0016 0.0037 0.008
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0022 0.0079 0.0079
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0085 0.0525 0.1815
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Trypanosoma brucei trypanothione reductase 0.0037 0.0184 0.0184
Trichomonas vaginalis abcb9, putative 0.0028 0.0118 0.074
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0015 0.0028 0.0168
Toxoplasma gondii hypothetical protein 0.0066 0.0391 0.0861
Brugia malayi Guanylyl cyclase protein 23 0.0056 0.0319 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0354 0.2243
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0208 0.1394 0.1394
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0015 0.0026 0.0026
Brugia malayi Thioredoxin reductase 0.0037 0.0184 0.0184
Toxoplasma gondii isocitrate dehydrogenase 0.0027 0.011 0.0243
Loa Loa (eye worm) hypothetical protein 0.1152 0.8096 0.8096
Echinococcus multilocularis carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) hypothetical protein 0.1017 0.7138 0.7138
Brugia malayi MH2 domain containing protein 0.0189 0.1263 0.1263
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0012 0.0025
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0077 0.0467 0.0467
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.0118 0.074
Schistosoma mansoni hypothetical protein 0.0066 0.0387 0.0387
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0048 0.0259 0.0259
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0058 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0086 0.0529 0.0529
Onchocerca volvulus 0.0134 0.0874 0.1078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Entamoeba histolytica P-glyco protein 6, putative 0.0028 0.0118 0.0605
Entamoeba histolytica P-glycoprotein-5 0.0028 0.0118 0.0605
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0259 0.2117
Echinococcus multilocularis transient receptor potential gamma protein 0.0253 0.1715 0.1715
Brugia malayi hypothetical protein 0.0056 0.0319 0.0319
Loa Loa (eye worm) glutamate receptor 0.0597 0.4156 0.4156
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0006 0.0006
Brugia malayi cytoplasmic intermediate filament protein 0.0011 0.0002 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0066 0.0387 0.1336
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0001
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0153 0.1007 0.1007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0319 0.0319
Brugia malayi Transient-receptor-potential like protein 0.0094 0.0589 0.0589
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0012 0.0068
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0047 0.0254 0.0254
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Echinococcus granulosus lamin 0.0021 0.0071 0.0071
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0085 0.0525 0.0525
Echinococcus multilocularis multidrug resistance associated protein 4 0.0031 0.0138 0.0138
Echinococcus multilocularis GPCR, family 2 0.0066 0.0387 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0228 0.0228
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0015 0.0028 0.0028
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0047 0.0254 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Mycobacterium ulcerans putative regulatory protein 0.0028 0.0121 0.0994
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0011 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Schistosoma mansoni tyrosine kinase 0.0056 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0083
Toxoplasma gondii 6-phosphofructokinase 0.0023 0.0085 0.0186
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0651 0.4539 0.4539
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0015 0.0027 0.0027
Brugia malayi hypothetical protein 0.0077 0.0467 0.0467
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0228 0.0228
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0228 0.0228
Onchocerca volvulus 0.003 0.0136 0.0167
Brugia malayi follicle stimulating hormone receptor 0.0181 0.1208 0.1208
Onchocerca volvulus Alhambra homolog 0.0029 0.0124 0.0152
Brugia malayi beta-lactamase 0.0066 0.0387 0.0387
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0387 0.0387
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0124 0.0124
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0053 0.0053
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Onchocerca volvulus 0.0043 0.0228 0.028
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0228 0.0228
Schistosoma mansoni organic anion transporter 0.0022 0.0076 0.0076
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0027 0.011 0.011
Brugia malayi MH2 domain containing protein 0.0013 0.0013 0.0013
Brugia malayi hypothetical protein 0.0022 0.0076 0.0076
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0012 0.0012
Giardia lamblia Histone acetyltransferase GCN5 0.0034 0.0159 0.0958
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0066 0.0066
Trichomonas vaginalis esterase, putative 0.0066 0.0387 0.2448
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0015 0.0028 0.0028
Plasmodium vivax SET domain protein, putative 0.003 0.0136 0.0811
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0053 0.0179
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0015 0.0027 0.006
Schistosoma mansoni hypothetical protein 0.0671 0.4684 0.4684
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0134 0.0874 0.0874
Loa Loa (eye worm) MH2 domain-containing protein 0.0189 0.1263 0.1263
Entamoeba histolytica ATP-binding cassette protein, putative 0.0047 0.0254 0.1501
Schistosoma mansoni follistatin 0.0015 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0066 0.0387 0.0387
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0228 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0328 0.2073
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0056 0.0319 0.0319
Trypanosoma cruzi hypothetical protein 0.0031 0.0138 0.0138
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0047 0.0254 0.0254
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Leishmania major pentamidine resistance protein 1 0.0047 0.0254 0.0254
Entamoeba histolytica P-glycoprotein-2 0.0028 0.0118 0.0605
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0016 0.0037 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0228 0.0228
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0016 0.0037 0.0305
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0066 0.0066
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0085 0.0525 0.0525
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0012 0.0068
Schistosoma mansoni nicalin (M28 family) 0.0183 0.1222 0.1222
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0013 0.0013
Plasmodium falciparum glutathione reductase 0.0013 0.0012 0.0025
Echinococcus granulosus ATP binding cassette sub family B 0.0016 0.0037 0.0037
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Trypanosoma cruzi extracellular receptor, putative 0.0056 0.0319 0.0319
Schistosoma mansoni carbonic anhydrase 0.0141 0.0923 0.0923
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Echinococcus multilocularis short transient receptor potential channel 6 0.0167 0.1108 0.1108
Plasmodium vivax ABC transporter B family member 6, putative 0.0016 0.0037 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0228 0.0228
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0015 0.0028 0.0028
Brugia malayi PXA domain containing protein 0.0015 0.0028 0.0028
Brugia malayi Regulator of G protein signaling domain containing protein 0.0015 0.0028 0.0028
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0184 0.0184
Entamoeba histolytica ATP-binding cassette protein, putative 0.0047 0.0254 0.1501
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0228 0.0228
Mycobacterium ulcerans hypothetical protein 0.0183 0.1222 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Brugia malayi hypothetical protein 0.002 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Onchocerca volvulus 0.0015 0.0027 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0019 0.0053 0.0183
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.011 0.011
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0066 0.0066
Brugia malayi hypothetical protein 0.0077 0.0467 0.0467
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1421 1 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0012 0.0043
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0228 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0228 0.0228
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0047 0.0254 0.056
Echinococcus granulosus glutamate receptor 2 0.0056 0.0319 0.0319
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0015 0.0027 0.0027
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0027 0.011 0.0655
Mycobacterium ulcerans carbonic anhydrase 0.0141 0.0923 0.7553
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0246 0.1668 0.1668
Brugia malayi hypothetical protein 0.0015 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0077 0.0467 0.0467
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0124 0.0124
Brugia malayi Pre-SET motif family protein 0.0205 0.1376 0.1376
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0228 0.0228
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0066 0.0387 0.0387
Plasmodium vivax ABC transporter B family member 4, putative 0.0016 0.0037 0.0217
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0183 0.1222 0.1222
Trichomonas vaginalis abcb9, putative 0.0028 0.0118 0.074
Plasmodium vivax ABC transporter B family member 7, putative 0.0016 0.0037 0.0217
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0016 0.0037 0.0228
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0001
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0085 0.0525 0.3346
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0016 0.0037 0.0305
Giardia lamblia Hypothetical protein 0.0016 0.0033 0.0136
Brugia malayi N-terminal motif family protein 0.0132 0.0857 0.0857
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0023 0.0085 0.0184
Echinococcus granulosus GPCR family 2 0.0066 0.0387 0.0387
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.008 0.049 0.1692
Trypanosoma cruzi glutaminyl cyclase, putative 0.0183 0.1222 0.1222
Entamoeba histolytica acyl-coA synthetase, putative 0.0019 0.0053 0.0179
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0001 0.0001
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0047 0.0254 0.0254
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0083 0.0083
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0015 0.0028 0.0028
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0012 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0012 0.0012
Brugia malayi Receptor family ligand binding region containing protein 0.0056 0.0319 0.0319
Loa Loa (eye worm) hypoxia-induced factor 1 0.0118 0.0758 0.0758
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0246 0.1668 0.1668
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0011 0.0001 0.0003
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0735 0.5134 0.5134
Schistosoma mansoni intermediate filament proteins 0.0021 0.0071 0.0071
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0449 0.0449
Mycobacterium ulcerans carbonic anhydrase 0.0061 0.0354 0.2901
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0022 0.0079 0.0079
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0246 0.1667 1
Entamoeba histolytica hypothetical protein 0.0058 0.0333 0.2018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0269 0.0269
Schistosoma mansoni glutamate receptor NMDA 0.0056 0.0319 0.0319
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0795 0.556 0.556
Brugia malayi tailless protein 0.002 0.0066 0.0066
Echinococcus granulosus sodium:glucose cotransporter 2 0.0032 0.0147 0.0147
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0037 0.0082
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0001 0.0001
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0132 0.0857 0.1057
Onchocerca volvulus 0.0134 0.0874 0.1078
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0028 0.0028
Echinococcus granulosus multidrug resistance protein 1 0.0028 0.0118 0.0118
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0319 0.0319
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0028 0.0118 0.0118
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0022 0.0079 0.0079
Toxoplasma gondii exonuclease III APE 0.0015 0.0026 0.0057
Brugia malayi CXXC zinc finger family protein 0.0047 0.0256 0.0256
Brugia malayi hypothetical protein 0.0128 0.0828 0.0828
Echinococcus granulosus metabotropic glutamate receptor 5 0.0735 0.5134 0.5134
Loa Loa (eye worm) PXA domain-containing protein 0.0015 0.0028 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0136 0.0136
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0028 0.0118 0.074
Mycobacterium ulcerans 6-phosphofructokinase 0.0085 0.0525 0.4299
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0015 0.0028 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0053 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0066 0.0066
Schistosoma mansoni axis inhibition protein axin 0.0015 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0228 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0228 0.0228
Schistosoma mansoni cpg binding protein 0.005 0.0275 0.0275
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0023 0.0085 0.6844
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0026 0.0148
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.011 0.011
Brugia malayi Cytochrome P450 family protein 0.0018 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0212 0.0212
Echinococcus multilocularis ATP binding cassette sub family B 0.0016 0.0037 0.0037
Plasmodium falciparum multidrug resistance-associated protein 2 0.0016 0.0037 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0026 0.0156
Schistosoma mansoni hypothetical protein 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0077 0.0467 0.0467
Brugia malayi Cytochrome P450 family protein 0.0041 0.0212 0.0212
Echinococcus granulosus multidrug resistance protein 1 0.0028 0.0118 0.0118
Onchocerca volvulus 0.0022 0.0076 0.0093
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0028 0.0028
Brugia malayi hypoxia-induced factor 1 0.0118 0.0758 0.0758
Brugia malayi multidrug resistance protein 3 0.0028 0.0118 0.0118
Schistosoma mansoni Smad4 0.0013 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0058 0.0333 0.0333
Brugia malayi PXA domain containing protein 0.0015 0.0028 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0228 0.0228
Onchocerca volvulus 0.0032 0.0147 0.018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0097 0.0609 0.0609
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0032 0.0147 0.0147
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.011 0.011
Echinococcus granulosus multidrug resistance protein 1 0.0028 0.0118 0.0118
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0208 0.1394 0.1394
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0015 0.0026 0.0026
Loa Loa (eye worm) POT family protein 0.0032 0.0148 0.0148
Brugia malayi jmjC domain containing protein 0.0037 0.0186 0.0186
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0029 0.0124 0.0124
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0228 0.028
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0183 0.1222 0.1222
Echinococcus multilocularis glutamate receptor 2 0.0056 0.0319 0.0319
Loa Loa (eye worm) acetyltransferase 0.0124 0.0804 0.0804
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0019 0.0053 0.0434
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0001 0.0001
Echinococcus multilocularis agrin 0.0015 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0053
Brugia malayi Smad1 0.0013 0.0013 0.0013
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0001 0.0001
Giardia lamblia Multidrug resistance-associated protein 1 0.0047 0.0254 0.1576
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0008 0.0041
Echinococcus multilocularis beta LACTamase domain containing family member 0.0066 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Loa Loa (eye worm) hypothetical protein 0.0097 0.0609 0.0609
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0012 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0012 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0387 0.0387
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0022 0.0079 0.0495
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0228 0.0228
Onchocerca volvulus Fxna peptidase homolog 0.0183 0.1222 0.1508
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0083 0.0083
Schistosoma mansoni ap endonuclease 0.0015 0.0026 0.0026
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0228 0.0228
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0001 0.0001
Brugia malayi PHD-finger family protein 0.0029 0.0124 0.0124
Mycobacterium tuberculosis Conserved protein 0.0066 0.0387 0.1336
Plasmodium vivax 6-phosphofructokinase, putative 0.0023 0.0085 0.0501
Schistosoma mansoni carbonic anhydrase-related 0.0651 0.4539 0.4539
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0016 0.0037 0.0037
Onchocerca volvulus 0.0077 0.0467 0.0576
Echinococcus granulosus regulator of G protein signaling 3 0.0015 0.0028 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0229 0.1546 1
Schistosoma mansoni zinc finger protein 0.002 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Toxoplasma gondii thioredoxin reductase 0.0037 0.0184 0.0406
Entamoeba histolytica P-glycoprotein 6, putative 0.0016 0.0037 0.0075
Brugia malayi nuclear receptor NHR-88 0.0043 0.0228 0.0228
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0184 0.0636
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0228 0.0228
Trichomonas vaginalis ABC transporter, putative 0.0028 0.0118 0.074
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.1222 0.7753
Schistosoma mansoni multidrug resistance protein 0.0016 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Leishmania major p-glycoprotein e 0.0047 0.0254 0.0254
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0001 0.0001
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0124 0.0273
Loa Loa (eye worm) hypothetical protein 0.0183 0.1222 0.1222
Leishmania major hypothetical protein, unknown function 0.0011 0.0001 0.0001
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0066 0.0066
Echinococcus multilocularis ATP binding cassette sub family B 0.0016 0.0037 0.0037
Brugia malayi isocitrate dehydrogenase 0.0027 0.011 0.011
Echinococcus multilocularis conserved hypothetical protein 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0183 0.1222 0.4221
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.0118 0.074
Schistosoma mansoni hypothetical protein 0.0392 0.2703 0.2703
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0015 0.0028 0.0028
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0228 0.0228
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0136 0.0136
Brugia malayi beta-lactamase family protein 0.0066 0.0387 0.0387
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0134 0.0874 0.0874
Brugia malayi hypothetical protein 0.0016 0.0037 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0058 0.0333 0.0333
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0048 0.0259 0.0894
Giardia lamblia Fructose-bisphosphate aldolase 0.0229 0.1546 1
Brugia malayi acetyltransferase, GNAT family protein 0.0124 0.0804 0.0804
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0097 0.0609 0.0609
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0001 0.0001
Trichomonas vaginalis ABC transporter, putative 0.0028 0.0118 0.074
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0032 0.0032
Trichomonas vaginalis ABC transporter, putative 0.0028 0.0118 0.074
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0066 0.0066
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0006 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0136 0.0136
Brugia malayi secreted modular calcium-binding protein 1 0.0015 0.0027 0.0027
Schistosoma mansoni transient receptor potential channel 4 0.0253 0.1715 0.1715
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0032 0.0147 0.0147
Echinococcus multilocularis transfer RNA-Lys 0.0028 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0467 0.0467
Plasmodium falciparum multidrug resistance-associated protein 1 0.0016 0.0037 0.008
Onchocerca volvulus 0.0077 0.0467 0.0576
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0028 0.0118 0.0118
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0094 0.0589 0.0589
Schistosoma mansoni nuclear receptor 0.002 0.0066 0.0066
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0016 0.0037 0.0037
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0016 0.0037 0.0129
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0181 0.1208 0.1208
Loa Loa (eye worm) hypothetical protein 0.0651 0.4539 0.4539
Entamoeba histolytica ABC transporter, putative 0.0047 0.0254 0.1501
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0016 0.0037 0.0305
Plasmodium vivax acyl-CoA synthetase, putative 0.0014 0.002 0.0112
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0066 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.0085 0.0528
Brugia malayi ABC transporter family protein 0.0016 0.0037 0.0037
Mycobacterium tuberculosis Probable lipase LipE 0.0066 0.0387 0.1336
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0015 0.0026 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0246 0.1668 0.1668
Brugia malayi nuclear receptor RXR 0.002 0.0066 0.0066
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0028 0.0118 0.026
Plasmodium falciparum glutathione reductase 0.0037 0.0184 0.0403
Trichomonas vaginalis D-aminoacylase, putative 0.0066 0.0387 0.2448
Brugia malayi Pre-SET motif family protein 0.003 0.0136 0.0136
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0028 0.0118 0.0118
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0033 0.0203
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0022 0.0079 0.0351
Giardia lamblia TCP-1 chaperonin subunit beta 0.0022 0.0079 0.0436
Schistosoma mansoni carbonic anhydrase 0.0651 0.4539 0.4539
Loa Loa (eye worm) beta-lactamase 0.0066 0.0387 0.0387
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0028 0.0028
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0061 0.0354 0.1224
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0077 0.0467 0.0467
Onchocerca volvulus 0.0021 0.0071 0.0087
Echinococcus granulosus multidrug resistance associated protein 4 0.0031 0.0138 0.0138
Brugia malayi MH1 domain containing protein 0.0013 0.0013 0.0013
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0097 0.0609 0.075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0136 0.0136
Onchocerca volvulus Poor gastrulation protein homolog 0.0097 0.0609 0.075
Schistosoma mansoni hypothetical protein 0.0198 0.1325 0.1325
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0016 0.0037 0.0037
Brugia malayi nuclear receptor NHR-67 0.002 0.0066 0.0066
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0016 0.0037 0.0404
Echinococcus granulosus solute carrier family 5 0.0032 0.0147 0.0147
Echinococcus granulosus Solute carrier family 22 5 0.0811 0.5674 0.5674
Echinococcus multilocularis ATP binding cassette sub family B 0.0016 0.0037 0.0037
Echinococcus multilocularis beta adrenergic receptor kinase 0.0015 0.0028 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0015 0.0026 0.0026
Mycobacterium tuberculosis Probable reductase 0.0084 0.0521 0.1799
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0066 0.008
Loa Loa (eye worm) isocitrate dehydrogenase 0.0027 0.011 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0014 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0053 0.0434
Schistosoma mansoni organic anion transporter 0.0022 0.0076 0.0076
Trypanosoma brucei hypothetical protein, conserved 0.0066 0.0387 0.0387
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0013 0.0013
Entamoeba histolytica ATP-binding cassette protein, putative 0.0047 0.0254 0.1501
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0066 0.0066
Plasmodium falciparum thioredoxin reductase 0.0013 0.0012 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0228 0.0228
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0047 0.0254 0.0254
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0012 0.0012
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0028 0.0118 0.0118
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0387 0.0387
Schistosoma mansoni regulator of G protein signaling 0.0015 0.0028 0.0028
Toxoplasma gondii transporter, major facilitator family protein 0.0022 0.0076 0.0168
Onchocerca volvulus 0.0066 0.0387 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.0183 0.1222 0.7753
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.011 0.011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0015 0.0026 0.0089
Brugia malayi multidrug resistance related protein 1 0.0047 0.0254 0.0254
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0056 0.0319 0.0393
Mycobacterium ulcerans hypothetical protein 0.0019 0.0053 0.0434
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0028 0.0118 0.074
Echinococcus granulosus Solute carrier organic anion transporter family 0.0022 0.0076 0.0076
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0013 0.0013
Echinococcus granulosus short transient receptor potential channel 6 0.0167 0.1108 0.1108
Schistosoma mansoni multidrug resistance protein 0.0047 0.0254 0.0254
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0136 0.0136
Mycobacterium tuberculosis Conserved protein 0.0066 0.0387 0.1336
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0083 0.0083
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0183 0.1222 0.1222
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0028 0.0028
Brugia malayi Nuclear hormone receptor E75 0.002 0.0066 0.0066
Loa Loa (eye worm) DR-78 0.002 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0229 0.1546 0.9808
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0028 0.0168
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0066 0.008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0027 0.011 0.0381
Loa Loa (eye worm) hypothetical protein 0.0057 0.0328 0.0328
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0013 0.0013
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0028 0.0118 0.0407
Loa Loa (eye worm) hypothetical protein 0.0056 0.0319 0.0319
Treponema pallidum exodeoxyribonuclease (exoA) 0.0015 0.0026 0.0088
Plasmodium falciparum ABC transporter B family member 3, putative 0.0016 0.0037 0.008
Loa Loa (eye worm) phosphofructokinase 0.0085 0.0525 0.0525
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.0049 0.0398
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0588 0.203
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0049 0.0049
Leishmania major hypothetical protein, conserved 0.0183 0.1222 0.1222
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0319 0.0319
Entamoeba histolytica acetyltransferase, GNAT family 0.0034 0.0159 0.0877
Brugia malayi POT family protein 0.0032 0.0148 0.0148
Mycobacterium tuberculosis Probable esterase LipL 0.0066 0.0387 0.1336
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0012 0.0027
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0124 0.0804 0.0804
Echinococcus granulosus axis inhibition protein axin 0.0015 0.0028 0.0028
Plasmodium vivax 6-phosphofructokinase, putative 0.0023 0.0085 0.0501
Loa Loa (eye worm) hypothetical protein 0.0153 0.1007 0.1007
Toxoplasma gondii isocitrate dehydrogenase 0.0027 0.011 0.0243
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0928 0.0928
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0228 0.0228
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0651 0.4539 0.4539
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0053 0.0053
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0056 0.0319 0.0319
Schistosoma mansoni multidrug resistance protein 0.0047 0.0254 0.0254
Brugia malayi hypothetical protein 0.0058 0.0333 0.0333
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0521 0.1799
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0047 0.0254 0.0254
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0053 0.0434
Loa Loa (eye worm) hypothetical protein 0.0128 0.0828 0.0828
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0153 0.1007 0.1007
Schistosoma mansoni aldehyde dehydrogenase 0.0048 0.0259 0.0259
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0016 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0066 0.0387 0.0387
Schistosoma mansoni hypothetical protein 0.0015 0.003 0.003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0184 0.0184
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0228 0.0228
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0023 0.0085 0.047
Schistosoma mansoni smad1 5 8 and 0.0013 0.0013 0.0013
Schistosoma mansoni metabotropic glutamate receptor 0.05 0.3468 0.3468
Echinococcus granulosus regulator of G protein signaling 3 0.0015 0.0028 0.0028
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0015 0.0027 0.006
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0184 0.1099
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0066 0.0066
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0525 0.3287
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0387 0.2316
Brugia malayi Intermediate filament tail domain containing protein 0.0021 0.0071 0.0071
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0387 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0228 0.0228
Echinococcus multilocularis receptor type guanylyl cyclase 0.0056 0.0319 0.0319
Echinococcus granulosus follistatin 0.0015 0.0027 0.0027
Onchocerca volvulus 0.0028 0.0118 0.0144
Schistosoma mansoni carbonic anhydrase-related 0.0651 0.4539 0.4539
Schistosoma mansoni Fxna peptidase (M28 family) 0.0183 0.1222 0.1222
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0056 0.0319 0.0319
Echinococcus granulosus metabotropic glutamate receptor 2 0.05 0.3468 0.3468
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0066 0.0387 0.1336
Schistosoma mansoni multidrug resistance protein 0.0028 0.0118 0.0118
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0028 0.0118 0.074
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.0118 0.074
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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