Detailed information for compound 1865338

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2215.74 | Formula: C68H86Na16O43S8
  • H donors: 16 H acceptors: 32 LogP: 0.07 Rotable bonds: 76
    Rule of 5 violations (Lipinski): 3
  • SMILES: [O-]C(=O)CC(C(=O)[O-])SCCCO[C@H]1[C@H](O[C@@H]2O[C@H](COCCCSC(C(=O)[O-])CC(=O)[O-])[C@H]([C@@H]([C@H]2OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])[C@@H](COCCCSC(C(=O)[O-])CC(=O)[O-])OC([C@@H]1OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
  • InChi: 1S/C68H102O43S8.16Na/c69-45(70)25-37(59(85)86)112-17-1-9-101-33-35-53(103-11-3-19-114-39(61(89)90)27-47(73)74)55(104-12-4-20-115-40(62(91)92)28-48(75)76)58(107-15-7-23-118-43(65(97)98)31-51(81)82)68(110-35)111-54-36(34-102-10-2-18-113-38(60(87)88)26-46(71)72)109-67(108-16-8-24-119-44(66(99)100)32-52(83)84)57(106-14-6-22-117-42(64(95)96)30-50(79)80)56(54)105-13-5-21-116-41(63(93)94)29-49(77)78;;;;;;;;;;;;;;;;/h35-44,53-58,67-68H,1-34H2,(H,69,70)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H,93,94)(H,95,96)(H,97,98)(H,99,100);;;;;;;;;;;;;;;;/q;16*+1/p-16/t35-,36-,37?,38?,39?,40?,41?,42?,43?,44?,53-,54-,55+,56+,57-,58-,67?,68+;;;;;;;;;;;;;;;;/m1................/s1
  • InChiKey: OOOQDKWTWZWMMG-MDZWFRESSA-A  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus EF hand domain containing family member A2 0.0118 0.0208 0.0208
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0083 0.0132 0.0303
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0039 0.0043
Giardia lamblia Serine peptidase, putative 0.0042 0.0043 0.0058
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0024 0.0031
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0057 0.0041
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0776 0.1629 0.1766
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Echinococcus multilocularis hypothetical protein 0.0944 0.1991 0.1991
Plasmodium vivax glutathione reductase, putative 0.0048 0.0057 0.0093
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0542 0.1123 0.2152
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0542 0.1123 0.1221
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0542 0.1123 0.3058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.2595
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0016 0.0014
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0019 0.0016
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1899 0.4052 0.4398
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma brucei hypothetical protein, conserved 0.0338 0.0682 0.1184
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0486 0.1003 0.109
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0024 0.0026
Trypanosoma brucei calmodulin, putative 0.0118 0.0208 0.0351
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Onchocerca volvulus 0.2426 0.5188 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Loa Loa (eye worm) fibroinase 0.2426 0.5188 0.5639
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0189 0.0173
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0235 0.0461 0.0496
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Loa Loa (eye worm) beta-lactamase 0.0036 0.0032 0.0035
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.0138 0.0251 0.0273
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0189 0.0173
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Loa Loa (eye worm) hypothetical protein 0.0389 0.0793 0.0861
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0043 0.0058
Echinococcus multilocularis Transglutaminase 0.0251 0.0496 0.0496
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Entamoeba histolytica hypothetical protein 0.0542 0.1123 0.2161
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0077 0.0084
Mycobacterium ulcerans putative transglutaminase-like protein 0.0251 0.0496 0.0481
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Plasmodium falciparum serine repeat antigen 8 0.0542 0.1123 0.2152
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Onchocerca volvulus 0.2426 0.5188 1
Leishmania major phospholipase c-like protein 0.0116 0.0204 0.0343
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Loa Loa (eye worm) calpain family protein 1 0.1608 0.3425 0.3722
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0189 0.0173
Toxoplasma gondii prolyl endopeptidase 0.1651 0.3518 0.6775
Trypanosoma brucei cysteine peptidase C (CPC) 0.17 0.3622 0.6349
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0012 0.0013
Echinococcus granulosus tumor protein p63 0.0344 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Brugia malayi Cytochrome P450 family protein 0.0058 0.0077 0.0084
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.1461 0.158
Loa Loa (eye worm) calpain 0.0944 0.1991 0.2164
Plasmodium vivax histone deacetylase, putative 0.0099 0.0167 0.0306
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0542 0.1123 0.1216
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1416 0.301 0.2999
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0057 0.0062
Schistosoma mansoni reticulocalbin 0.0116 0.0204 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0019 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Onchocerca volvulus 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.1461 0.1447
Trypanosoma brucei I/6 autoantigen 0.0116 0.0204 0.0343
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0019 0.0016
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0542 0.1123 0.2152
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0542 0.1123 0.2152
Mycobacterium ulcerans hypothetical protein 0.0036 0.0032 0.0016
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0028 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Onchocerca volvulus 0.0037 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0542 0.1123 0.2152
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Leishmania major programmed cell death 6 protein-like protein 0.0116 0.0204 0.0343
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Brugia malayi cathepsin F-like cysteine proteinase 0.0542 0.1123 0.1221
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4285 0.9202 1
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.4655 1 1
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 1
Toxoplasma gondii microneme protein, putative 0.0029 0.0016 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Trypanosoma brucei prolyl endopeptidase 0.1651 0.3518 0.6166
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0037 0.0033 0.0035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Giardia lamblia Hypothetical protein 0.0125 0.0222 0.0555
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Echinococcus multilocularis dna polymerase eta 0.0045 0.0051 0.0051
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0039 0.0037
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0215 0.02
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Brugia malayi Pre-SET motif family protein 0.0854 0.1797 0.1952
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0039 0.0042
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0222 0.0376
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.005 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0208 0.0208
Toxoplasma gondii microneme protein MIC4 0.0029 0.0016 0.0014
Brugia malayi proteasome subunit beta type 2 0.004 0.0039 0.0043
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Loa Loa (eye worm) proteasome subunit beta type 1 0.0064 0.0092 0.01
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.005 0.0062 0.0111
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019
Leishmania major i/6 autoantigen-like protein 0.0116 0.0204 0.0343
Brugia malayi hypothetical protein 0.0064 0.0092 0.01
Toxoplasma gondii preprocathepsin c precursor, putative 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0016 0.0014
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Loa Loa (eye worm) histone deacetylase 0.0099 0.0167 0.0181
Trypanosoma brucei unspecified product 0.0208 0.0403 0.0694
Echinococcus multilocularis pyruvate kinase 0.0026 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Echinococcus granulosus programmed cell death protein 0.0124 0.0221 0.0221
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0039 0.0039
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Giardia lamblia Glycogen phosphorylase 0.0105 0.0181 0.044
Trypanosoma brucei histone deacetylase 1 0.0088 0.0143 0.0237
Echinococcus granulosus EF hand domain containing family member A2 0.0116 0.0204 0.0204
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0024 0.0028
Echinococcus multilocularis calcium uptake protein 1 0.0118 0.0208 0.0208
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Leishmania major hypothetical protein, conserved 0.0118 0.0208 0.0351
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Leishmania major hypothetical protein, conserved 0.0045 0.005 0.0072
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0039 0.0039
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Echinococcus multilocularis EF hand domain containing family member A2 0.0116 0.0204 0.0204
Echinococcus granulosus histone deacetylase 8 0.0042 0.0045 0.0045
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0653 0.1363 0.238
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0019 0.0021
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Echinococcus multilocularis histone deacetylase 7 0.0099 0.0167 0.0167
Brugia malayi nuclear hormone receptor 0.0031 0.0019 0.0021
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.005 0.0054
Echinococcus granulosus calpain A 0.2282 0.4878 0.4878
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0026
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Trypanosoma brucei oligopeptidase b 0.0698 0.1461 0.2552
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0131 0.0236 0.0449
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0024 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Echinococcus multilocularis calpain family protein 1, d 0.1608 0.3425 0.3425
Echinococcus multilocularis lamin dm0 0.0027 0.0012 0.0012
Brugia malayi hypothetical protein 0.0224 0.0438 0.0475
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0012 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Onchocerca volvulus 0.0064 0.0092 0.0169
Trypanosoma brucei centrin-3 0.0124 0.0221 0.0374
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Entamoeba histolytica calpain large subunit domain III containing protein 0.0555 0.1152 0.2216
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Brugia malayi carbohydrate phosphorylase 0.0105 0.0181 0.0197
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Plasmodium vivax calpain, putative 0.0944 0.1991 0.3828
Brugia malayi RNA binding protein 0.0065 0.0094 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.005 0.0045
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0064 0.0092 0.0172
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.17 0.3622 0.6349
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0057 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0024 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0257 0.0279
Brugia malayi cathepsin F-like cysteine proteinase 0.0764 0.1601 0.174
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1135 0.2402 0.2604
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0019 0.0029
Brugia malayi calpain 5 0.0389 0.0793 0.0861
Echinococcus granulosus EF HAND 1 calcium binding site 0.0116 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Echinococcus multilocularis histone deacetylase 6 0.0105 0.018 0.018
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Echinococcus granulosus histone deacetylase 1 0.0088 0.0143 0.0143
Brugia malayi histone deacetylase 11 0.0042 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Schistosoma mansoni chromatin regulatory protein sir2 0.0138 0.0251 0.0268
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Onchocerca volvulus 0.0251 0.0496 0.0947
Mycobacterium tuberculosis Hypothetical protein 0.0251 0.0496 0.0481
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Loa Loa (eye worm) glutathione reductase 0.0048 0.0057 0.0062
Trypanosoma brucei small myristoylated protein 1-1 0.036 0.073 0.1267
Echinococcus multilocularis lamin 0.0027 0.0012 0.0012
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0023 0.0007
Toxoplasma gondii thioredoxin reductase 0.0048 0.0057 0.0093
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0051 0.0035
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0037 0.0033 0.003
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Schistosoma mansoni calpain C (C02 family) 0.0944 0.1991 0.216
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.1461 0.521
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Echinococcus granulosus neurocalcin 0.0116 0.0204 0.0204
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0085 0.0087
Trypanosoma brucei calmodulin, putative 0.0116 0.0204 0.0343
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Schistosoma mansoni calpain-2 (C02 family) 0.0389 0.0793 0.0857
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Onchocerca volvulus Matrilysin homolog 0.0053 0.0067 0.012
Plasmodium falciparum serine repeat antigen 2 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0228 0.0228
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Loa Loa (eye worm) prolyl oligopeptidase 0.0811 0.1705 0.1853
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Onchocerca volvulus 0.0116 0.0204 0.0384
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma brucei Calpain-like protein 1.2 0.0742 0.1555 0.2718
Echinococcus multilocularis geminin 0.0509 0.1053 0.1053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Brugia malayi fibroinase precursor 0.0542 0.1123 0.1221
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Echinococcus multilocularis calpain A 0.2282 0.4878 0.4878
Onchocerca volvulus 0.0036 0.0032 0.0053
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1651 0.3518 0.6166
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0094 0.0103
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Loa Loa (eye worm) cysteine protease 0.2426 0.5188 0.5639
Loa Loa (eye worm) ctsf protein 0.2426 0.5188 0.5639
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0143 0.0156
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0019 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0032 0.0016
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Loa Loa (eye worm) matrixin family protein 0.0057 0.0077 0.0084
Toxoplasma gondii centrin, putative 0.0116 0.0204 0.0377
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Brugia malayi MH2 domain containing protein 0.0253 0.0499 0.0543
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0189 0.0173
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.228 0.4874 0.4874
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0939 0.198 0.2144
Brugia malayi nuclear receptor NHR-88 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Toxoplasma gondii hypothetical protein 0.0235 0.0461 0.0873
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.1607
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Echinococcus granulosus survival motor neuron protein 1 0.0486 0.1003 0.1003
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1314 0.2789 0.2778
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Leishmania major hypothetical protein, conserved 0.0606 0.1262 0.2202
Schistosoma mansoni survival motor neuron protein 0.0099 0.0167 0.0177
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Onchocerca volvulus 0.0542 0.1123 0.2158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0542 0.1123 0.1213
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Brugia malayi Thioredoxin family protein 0.0251 0.0496 0.0539
Echinococcus multilocularis neuronal calcium sensor 0.0116 0.0204 0.0204
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Plasmodium falciparum cysteine proteinase falcipain 2b 0.2426 0.5188 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0032 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0118 0.0208 0.0217
Onchocerca volvulus 0.2426 0.5188 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0218 0.0218
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0499 0.0543
Loa Loa (eye worm) sirtuin 4 0.0032 0.0023 0.0025
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0003 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0019 0.0021
Echinococcus granulosus Mastin 0.0037 0.0033 0.0033
Echinococcus granulosus calpain 0.0944 0.1991 0.1991
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Leishmania major hypothetical protein, conserved 0.0116 0.0204 0.0343
Plasmodium falciparum cysteine proteinase falcipain 3 0.2426 0.5188 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0215 0.0719
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0811 0.1705 0.1848
Mycobacterium tuberculosis Probable reductase 0.0109 0.0189 0.0173
Trypanosoma brucei kinesin, putative 0.0555 0.1152 0.2009
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.1461 0.2552
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0024 0.0009
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0216 0.0364
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Leishmania major calpain family cysteine protease-like protein 0.0597 0.1243 0.2168
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0019 0.0019
Plasmodium falciparum proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0019 0.0029
Mycobacterium tuberculosis Probable peptidase 0.0698 0.1461 0.1447
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Plasmodium vivax centrin-1, putative 0.0116 0.0204 0.0377
Entamoeba histolytica protein kinase, putative 0.0555 0.1152 0.2216
Plasmodium falciparum serine repeat antigen 4 0.0542 0.1123 0.2152
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Echinococcus multilocularis microtubule associated protein 2 0.2086 0.4456 0.4456
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0542 0.1123 0.1221
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Toxoplasma gondii kringle domain-containing protein 0.0045 0.005 0.0079
Giardia lamblia Hypothetical protein 0.0251 0.0496 0.1314
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Plasmodium falciparum serine repeat antigen 1 0.0542 0.1123 0.2152
Echinococcus multilocularis inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0064 0.0092 0.0161
Toxoplasma gondii cathepsin B 0.17 0.3622 0.6975
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Brugia malayi steroid hormone receptor 0.0031 0.0019 0.0021
Onchocerca volvulus 0.0045 0.005 0.0087
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Trichomonas vaginalis hypothetical protein 0.0389 0.0793 0.1528
Schistosoma mansoni cathepsin B (C01 family) 0.0542 0.1123 0.1216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0019 0.0016
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0035 0.0028 0.0031
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0216 0.0216
Toxoplasma gondii proteasome subunit beta type 2, putative 0.004 0.0039 0.0059
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Echinococcus multilocularis proteasome (prosome, macropain) 0.0083 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0189 0.0173
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0019 0.0016
Leishmania major small myristoylated protein-1 0.036 0.073 0.1267
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0039 0.0042
Loa Loa (eye worm) RNA binding protein 0.0065 0.0094 0.0103
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0143 0.0156
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0542 0.1123 0.2152
Trypanosoma brucei cysteine peptidase, putative 0.0597 0.1243 0.2168
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0045 0.0071
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Echinococcus multilocularis caspase 2 0.0061 0.0085 0.0085
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0083 0.0132 0.0116
Leishmania major small myristoylated protein 4, putative 0.0567 0.1177 0.2053
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.17 0.3622 0.698
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Trypanosoma cruzi cruzipain precursor, putative 0.0764 0.1601 0.1733
Onchocerca volvulus 0.0099 0.0167 0.0314
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trypanosoma brucei proteasome beta 6 subunit 0.0064 0.0092 0.0147
Loa Loa (eye worm) histone deacetylase 7A 0.0099 0.0167 0.0181
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Brugia malayi hypothetical protein 0.0154 0.0286 0.031
Trichomonas vaginalis set domain proteins, putative 0.0972 0.2051 0.3954
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0023 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.1517 0.265
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0037 0.0033 0.0033
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Echinococcus multilocularis centrin 2 0.0116 0.0204 0.0204
Brugia malayi Papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0039 0.0039
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Echinococcus multilocularis calpain 0.0944 0.1991 0.1991
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0542 0.1123 0.2165
Mycobacterium ulcerans thymidine phosphorylase 0.4655 1 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Echinococcus granulosus cathepsin L cysteine protease 0.1306 0.2771 0.2771
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Schistosoma mansoni centrin-related 0.0116 0.0204 0.0217
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0086 0.014 0.014
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Echinococcus granulosus cathepsin L 0.0542 0.1123 0.1123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Leishmania major oligopeptidase b 0.0698 0.1461 0.2552
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Echinococcus granulosus tar DNA binding protein 0.0065 0.0094 0.0094
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni memapsin-2 (A01 family) 0.0429 0.0879 0.095
Echinococcus granulosus cysteine protease 0.1306 0.2771 0.2771
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0032 0.0016
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Brugia malayi Calmodulin-like protein 0.0116 0.0204 0.0221
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.0033
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0039 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0032 0.0041
Loa Loa (eye worm) hypothetical protein 0.0106 0.0182 0.0198
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus granulosus cathepsin L 0.1306 0.2771 0.2771
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0343
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Leishmania major cysteine peptidase A (CPA) 0.2426 0.5188 0.9102
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Echinococcus multilocularis Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0208 0.0403 0.043
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Leishmania major hypothetical protein, conserved 0.0338 0.0682 0.1184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0039 0.0033
Entamoeba histolytica hypothetical protein, conserved 0.0235 0.0461 0.0883
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Trypanosoma cruzi caltractin, putative 0.0116 0.0204 0.0212
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Echinococcus granulosus inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Mycobacterium ulcerans beta-lactamase 0.0036 0.0032 0.0016
Schistosoma mansoni intermediate filament proteins 0.0027 0.0012 0.0008
Plasmodium vivax vivapain-3 0.1306 0.2771 0.5334
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Onchocerca volvulus 0.0064 0.0092 0.0169
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0019 0.0016
Schistosoma mansoni ef hand domain family member A2 0.0116 0.0204 0.0217
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0023 0.0027
Giardia lamblia Histone deacetylase 0.0088 0.0143 0.0336
Mycobacterium leprae Probable lipase LipE 0.0036 0.0032 0.0059
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0045 0.0078
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Onchocerca volvulus 0.0118 0.0208 0.0393
Trichomonas vaginalis calmodulin-2, putative 0.0116 0.0204 0.0393
Toxoplasma gondii troponin c, isotype gamma, putative 0.0116 0.0204 0.0377
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0216 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Leishmania major hypothetical protein, conserved 0.0036 0.0032 0.0041
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0028 0.0049
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trypanosoma brucei conserved protein 0.0217 0.0423 0.0728
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0264 0.0524 0.0905
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0542 0.1123 0.2152
Trichomonas vaginalis calcium binding proteins, putative 0.0116 0.0204 0.0393
Echinococcus multilocularis thyroid hormone receptor alpha 0.0158 0.0294 0.0294
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0222 0.0242
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0116 0.0204 0.0212
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Toxoplasma gondii hypothetical protein 0.0389 0.0793 0.1514
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Leishmania major small myristoylated protein-3, putative 0.0305 0.0611 0.1059
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0064 0.0092 0.0177
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Echinococcus granulosus glycoprotein Antigen 5 0.0037 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0138 0.0251 0.0635
Entamoeba histolytica cysteine proteinase, putative 0.1662 0.354 0.6822
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0032 0.0035
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Trypanosoma brucei trypanothione reductase 0.0048 0.0057 0.0085
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0597 0.1243 0.1342
Mycobacterium ulcerans hypothetical protein 0.0037 0.0033 0.0017
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma brucei Component of motile flagella 41 0.0116 0.0204 0.0343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0039 0.0042
Leishmania major calpain protease-like protein 0.0389 0.0793 0.1378
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0023 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0022 0.0015
Onchocerca volvulus 0.0027 0.0012 0.0015
Plasmodium vivax unspecified product 0.1306 0.2771 0.5334
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0039 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Brugia malayi calpain 7 0.0944 0.1991 0.2164
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0028 0.0028
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0023 0.0027
Plasmodium falciparum histone deacetylase 2 0.0099 0.0167 0.0306
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0389 0.0793 0.1378
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0028 0.0035
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Schistosoma mansoni inhibitor of apoptosis protein 0.0132 0.0239 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0237
Schistosoma mansoni cathepsin s 0.0764 0.1601 0.1736
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0023 0.0038
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.3484
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0032 0.0059
Leishmania major hypothetical protein, unknown function 0.0389 0.0793 0.1378
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Trypanosoma brucei mitochondrial calcium uptake 1 0.0116 0.0204 0.0343
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Leishmania major calcineurin B subunit, putative 0.0116 0.0204 0.0343
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Toxoplasma gondii subtilisin SUB12 0.0029 0.0016 0.0014
Echinococcus granulosus acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Loa Loa (eye worm) hypothetical protein 0.2164 0.4623 0.5024
Brugia malayi glutathione reductase 0.0048 0.0057 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Onchocerca volvulus 0.0037 0.0033 0.0054
Echinococcus granulosus expressed protein 0.0769 0.1614 0.1614
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0257 0.0279
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0116 0.0204 0.0204
Echinococcus multilocularis transmembrane protease serine 3 0.0037 0.0033 0.0033
Onchocerca volvulus 0.0029 0.0016 0.0021
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Onchocerca volvulus 0.0036 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0343
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Brugia malayi beta-lactamase 0.0036 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Echinococcus granulosus peroxidasin 0.0064 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0224 0.0438 0.0475
Schistosoma mansoni reticulocalbin 0.0118 0.0208 0.0221
Onchocerca volvulus Prolyl endopeptidase homolog 0.1651 0.3518 0.6777
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0043 0.0038
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0459 0.0945 0.1808
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0064 0.0092 0.0092
Echinococcus granulosus histone deacetylase 3 0.0088 0.0143 0.0143
Plasmodium falciparum histone deacetylase, putative 0.0099 0.0167 0.0306
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0037 0.0033 0.0033
Plasmodium falciparum serine repeat antigen 3 0.0542 0.1123 0.2152
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0542 0.1123 0.2152
Schistosoma mansoni hypothetical protein 0.0127 0.0228 0.0243
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Brugia malayi Proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Plasmodium falciparum glutathione reductase 0.0048 0.0057 0.0093
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Toxoplasma gondii calmodulin CAM1 0.0118 0.0208 0.0386
Toxoplasma gondii EFHC1, putative 0.0116 0.0204 0.0377
Echinococcus granulosus calbindin 32 0.0118 0.0208 0.0208
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0208 0.0386
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0037 0.0033 0.0033
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0051 0.0074
Loa Loa (eye worm) calpain family protein 1 0.2164 0.4623 0.5024
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Toxoplasma gondii calcium-dependent protein kinase 0.0118 0.0208 0.0386
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0039 0.0039
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0116 0.0204 0.0217
Schistosoma mansoni histone deacetylase hda2 0.0105 0.018 0.0191
Echinococcus multilocularis prolyl endopeptidase 0.1651 0.3518 0.3518
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Trypanosoma cruzi unspecified product 0.036 0.073 0.0784
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0208 0.0403 0.0694
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0023 0.0038
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0023 0.0038
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Toxoplasma gondii cathepsin CPC2 0.0542 0.1123 0.2152
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Trypanosoma brucei Calpain-like protein 1.1 0.0939 0.198 0.3464
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0068
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0499 0.0543
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1306 0.2771 0.3005
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Leishmania major silent information regulator 2, putative 0.0125 0.0222 0.0376
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.057 0.1183 0.2063
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Onchocerca volvulus 0.0029 0.0016 0.0021
Giardia lamblia Encystation-specific protease 0.0542 0.1123 0.3058
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Plasmodium falciparum serine repeat antigen 9 0.0542 0.1123 0.2152
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0032 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Brugia malayi proteasome subunit beta type 1 0.0064 0.0092 0.01
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.2426 0.5188 1
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 0.2778
Mycobacterium ulcerans proteasome PrcB 0.0083 0.0132 0.0116
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Plasmodium falciparum thioredoxin reductase 0.0048 0.0057 0.0093
Echinococcus multilocularis tumor protein p63 0.0344 0.0696 0.0696
Echinococcus multilocularis enteropeptidase 0.0037 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi Hemopexin family protein 0.0034 0.0026 0.0028
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0228 0.0228
Leishmania major kinesin, putative 0.0555 0.1152 0.2009
Plasmodium falciparum calpain 0.0389 0.0793 0.1514
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Brugia malayi Histone deacetylase 1 0.0088 0.0143 0.0156
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.005 0.0079
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni hypothetical protein 0.0251 0.0496 0.0534
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Echinococcus granulosus histone deacetylase 7 0.0099 0.0167 0.0167
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0023 0.0027
Trypanosoma cruzi prolyl endopeptidase 0.1651 0.3518 0.3817
Loa Loa (eye worm) calpain D 0.0389 0.0793 0.0861
Plasmodium falciparum histone deacetylase 1 0.0088 0.0143 0.0261
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0028 0.0028
Loa Loa (eye worm) programmed cell death protein 6 0.0118 0.0208 0.0226
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.1486 0.1607
Echinococcus multilocularis calpain 7 (C02 family) 0.0944 0.1991 0.1991
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Trypanosoma brucei protein I/6 0.0116 0.0204 0.0343
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trypanosoma cruzi centrin-3 0.0124 0.0221 0.0232
Echinococcus multilocularis glycoprotein Antigen 5 0.0037 0.0033 0.0033
Echinococcus granulosus cathepsin l1 0.1662 0.354 0.354
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0051 0.0075
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0094 0.0094
Onchocerca volvulus 0.0972 0.2052 0.395
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0189 0.0625
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0143 0.0271
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0764 0.1601 0.174
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0028 0.0022
Plasmodium falciparum pyruvate kinase 0.0033 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.17 0.3622 0.393
Entamoeba histolytica grainin, putative 0.0118 0.0208 0.0396
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0024 0.0026
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Echinococcus multilocularis neurocalcin 0.0116 0.0204 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Brugia malayi EF hand family protein 0.0118 0.0208 0.0226
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Echinococcus multilocularis peroxidasin 0.0064 0.0092 0.0092
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Brugia malayi Protein kinase domain containing protein 0.0045 0.005 0.0054
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.2604
Loa Loa (eye worm) trypsin family protein 0.0037 0.0033 0.0035
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.005 0.0079
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0542 0.1123 0.2152
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0032 0.0016
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0039 0.0039
Onchocerca volvulus Matrix metalloproteinase homolog 0.0053 0.0067 0.012
Plasmodium falciparum peptidase, putative 0.0235 0.0461 0.0873
Loa Loa (eye worm) hypothetical protein 0.0321 0.0646 0.0702
Trypanosoma brucei calpain, putative 0.0389 0.0793 0.1378
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0032 0.0016
Trichomonas vaginalis esterase, putative 0.0036 0.0032 0.0062
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0043 0.0047
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Plasmodium vivax proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Echinococcus granulosus geminin 0.0509 0.1053 0.1053
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Trypanosoma brucei histone deacetylase 4 0.0099 0.0167 0.0278
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0143 0.0261
Brugia malayi prolyl oligopeptidase family protein 0.0811 0.1705 0.1853
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0116 0.0204 0.0393
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Trypanosoma brucei histone deacetylase 2 0.0042 0.0045 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0019 0.0019
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Plasmodium vivax histone deacetylase 2, putative 0.0099 0.0167 0.0306
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Echinococcus granulosus tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0149 0.0276 0.0295
Loa Loa (eye worm) cathepsin B 0.17 0.3622 0.3936
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0204 0.0343
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0092 0.0169
Plasmodium falciparum proteasome subunit beta type-5 0.0083 0.0132 0.0238
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Echinococcus granulosus microtubule associated protein 2 0.2086 0.4456 0.4456
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0012 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Echinococcus multilocularis EF hand domain containing family member A2 0.0118 0.0208 0.0208
Brugia malayi Cell death protein 3 precursor 0.0061 0.0085 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Brugia malayi hypothetical protein 0.0026 0.0008 0.0009
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Echinococcus multilocularis expressed protein 0.0769 0.1614 0.1614
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0028 0.0038
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0023 0.0025
Onchocerca volvulus 0.0029 0.0016 0.0021
Brugia malayi hypothetical protein 0.0061 0.0085 0.0092
Trichomonas vaginalis calmodulin, putative 0.0124 0.0221 0.0427
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0056 0.0075 0.0082
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus multilocularis Mastin 0.0037 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Plasmodium falciparum cysteine proteinase falcipain 2a 0.2426 0.5188 1
Loa Loa (eye worm) peptidase C13 family protein 0.0149 0.0276 0.03
Trypanosoma brucei Calpain-like protein 2 0.0724 0.1517 0.265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Leishmania major DNA polymerase eta, putative 0.0032 0.0022 0.0024
Onchocerca volvulus 0.0116 0.0204 0.0384
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0264 0.0524 0.0905
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.1461 0.158
Leishmania major sir2-family protein-like protein 0.0032 0.0023 0.0025
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0092 0.01
Onchocerca volvulus 0.0037 0.0033 0.0054
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Loa Loa (eye worm) glycogen phosphorylase 0.0105 0.0181 0.0197
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Echinococcus granulosus transmembrane protease serine 3 0.0037 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0009
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Brugia malayi prolyl oligopeptidase family protein 0.1651 0.3518 0.3823
Schistosoma mansoni cathepsin S (C01 family) 0.0542 0.1123 0.1216
Leishmania major trypanothione reductase 0.0048 0.0057 0.0085
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Plasmodium falciparum serine repeat antigen 7 0.0542 0.1123 0.2152
Brugia malayi cathepsin L-like cysteine proteinase 0.0542 0.1123 0.1221
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0023 0.0007
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0083 0.0132 0.0216
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Trypanosoma brucei histone deacetylase, putative 0.0099 0.0167 0.0278
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0389 0.0793 0.1514
Brugia malayi cathepsin L-like precursor 0.1662 0.354 0.3847
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0019 0.0016
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0218 0.0404
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Onchocerca volvulus Cathepsin F homolog 0.2426 0.5188 1
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0045 0.0049
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0046 0.0072
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0019 0.0021
Echinococcus granulosus calmodulin 0.0116 0.0204 0.0204
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni hypothetical protein 0.0115 0.0201 0.0214
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Onchocerca volvulus 0.2426 0.5188 1
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Brugia malayi Matrixin family protein 0.0057 0.0077 0.0084
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0866 0.1823 0.1823
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0389 0.0793 0.1378
Schistosoma mansoni calmodulin related calcium binding protein 0.0116 0.0204 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Plasmodium falciparum cysteine proteinase falcipain 1 0.1306 0.2771 0.5334
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Chlamydia trachomatis glycogen phosphorylase 0.0105 0.0181 1
Mycobacterium ulcerans transglutaminase family protein 0.0251 0.0496 0.0481
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0118 0.0208 0.0396
Brugia malayi EF hand family protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0034 0.0026 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0051 0.0056
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0019 0.0016
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.0516
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Plasmodium vivax histone deacetylase, putative 0.0042 0.0045 0.0071
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0039 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.1306 0.2771 0.3005
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0057 0.0052
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0039 0.0042
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Loa Loa (eye worm) hypothetical protein 0.0045 0.0051 0.0056
Onchocerca volvulus 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Schistosoma mansoni microtubule-associated protein tau 0.2086 0.4456 0.484
Entamoeba histolytica calcium binding family protein 0.0116 0.0204 0.0387
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Echinococcus granulosus histone deacetylase 0.0099 0.0167 0.0167
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma cruzi cysteine protease, putative 0.1306 0.2771 0.3005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0019 0.0016
Echinococcus granulosus dna polymerase eta 0.0045 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Schistosoma mansoni coup transcription factor 0.0031 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Entamoeba histolytica cysteine proteinase 2 0.1306 0.2771 0.5339
Giardia lamblia Pyruvate kinase 0.0033 0.0024 0.0005
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0235 0.0461 0.0501
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0019 0.0016
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Brugia malayi Peptidase C13 family protein 0.0149 0.0276 0.03
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0143 0.0261
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0052 0.0094
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0032 0.0016
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Echinococcus granulosus histone deacetylase 6 0.0105 0.018 0.018
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0019 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Brugia malayi Thioredoxin reductase 0.0048 0.0057 0.0062
Echinococcus multilocularis Glycosyl transferase, family 35 0.0105 0.0181 0.0181
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Brugia malayi programmed cell death protein 6 0.0116 0.0204 0.0221
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0086 0.014 0.014
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) calpain 5 0.0555 0.1152 0.1252
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Brugia malayi calpain 5 0.0555 0.1152 0.1252
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0024 0.0028
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0051 0.0046
Onchocerca volvulus 0.0122 0.0218 0.0411
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0561
Echinococcus granulosus lamin dm0 0.0027 0.0012 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0218 0.0232
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0143 0.0156
Loa Loa (eye worm) hypothetical protein 0.1775 0.3784 0.4112
Echinococcus multilocularis calumenin 0.0118 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Schistosoma mansoni cathepsin F (C01 family) 0.1662 0.354 0.3844
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.2426 0.5188 0.5639
Onchocerca volvulus 0.0029 0.0016 0.0021
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0235 0.0461 0.0795
Echinococcus granulosus calpain 5 0.0944 0.1991 0.1991
Onchocerca volvulus Glycogen phosphorylase homolog 0.0105 0.0181 0.034
Trypanosoma cruzi cysteine peptidase, putative 0.0764 0.1601 0.1733
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Echinococcus multilocularis survival motor neuron protein 1 0.0486 0.1003 0.1003
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Leishmania major cytochrome p450-like protein 0.0045 0.0051 0.0074
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0143 0.0143
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0083 0.0132 0.0254
Brugia malayi ecdysteroid receptor 0.0031 0.0019 0.0021
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0542 0.1123 0.1216
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0045 0.0044
Echinococcus multilocularis calbindin 32 0.0118 0.0208 0.0208
Brugia malayi hypothetical protein 0.0123 0.0219 0.0238
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0039 0.0054
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0542 0.1123 0.2152
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0039 0.0054
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0083 0.0132 0.0418
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0085 0.0154
Schistosoma mansoni Mername-AA248 (C02 family) 0.0944 0.1991 0.216
Brugia malayi Cathepsin L-like cysteine proteinase 0.1662 0.354 0.3847
Onchocerca volvulus 0.0029 0.0016 0.0021
Onchocerca volvulus 0.0037 0.0033 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Schistosoma mansoni mitochondrial solute carrier 0.0116 0.0204 0.0217
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Brugia malayi Trypsin-like protease protein 5 0.0037 0.0033 0.0035
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2164 0.4623 0.5022
Loa Loa (eye worm) hypothetical protein 0.0345 0.0699 0.0759
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0094 0.0103
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Echinococcus multilocularis thymidine phosphorylase 0.4655 1 1
Echinococcus multilocularis acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0116 0.0204 0.0212
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.2426 0.5188 0.5639
Trypanosoma brucei Calpain-like protein CALP1.3 0.0597 0.1243 0.2168
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0043 0.0068
Trichomonas vaginalis peptide N-glycanase, putative 0.0251 0.0496 0.0955
Echinococcus granulosus enteropeptidase 0.0037 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.0054
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0338 0.0682 0.1315
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0567 0.1177 0.1271
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0088 0.0143 0.0156
Echinococcus multilocularis calpain 5 0.0944 0.1991 0.1991
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0042 0.0045 0.0049
Trypanosoma cruzi cruzipain precursor, putative 0.2663 0.57 0.6191
Echinococcus granulosus cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0083 0.0132 0.0248
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0019 0.0019
Echinococcus granulosus calpain A 0.0944 0.1991 0.1991
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0083 0.0132 0.0138
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.4207
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.122 0.2585 0.281
Schistosoma mansoni DNA polymerase eta 0.0045 0.0051 0.0051
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0032 0.0016
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0064 0.0092 0.0095
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0043 0.0084
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.1651 0.3518 0.3823
Schistosoma mansoni calpain (C02 family) 0.0944 0.1991 0.216
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0039 0.0075
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Toxoplasma gondii cathepsin CPL 0.2426 0.5188 1
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0216 0.04
Onchocerca volvulus 0.0064 0.0092 0.0169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma cruzi cysteine peptidase, putative 0.2426 0.5188 0.5634
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Trypanosoma brucei caltractin, putative 0.0124 0.0221 0.0374
Trypanosoma brucei calpain, putative 0.0653 0.1363 0.238
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0389 0.0793 0.1528
Onchocerca volvulus 0.0034 0.0026 0.0041
Echinococcus granulosus calumenin 0.0118 0.0208 0.0208
Trypanosoma cruzi small myristoylated protein 1-2 0.036 0.073 0.0784
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Schistosoma mansoni cathepsin C 0.0542 0.1123 0.1216
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Onchocerca volvulus 0.0029 0.0016 0.0021
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0064 0.0092 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Onchocerca volvulus 0.0061 0.0085 0.0154
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Plasmodium falciparum centrin-1 0.0116 0.0204 0.0377
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0051 0.0055
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0045 0.0044
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Loa Loa (eye worm) prolyl oligopeptidase 0.0235 0.0461 0.0501
Loa Loa (eye worm) matrixin family protein 0.0053 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0043 0.0042
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Brugia malayi cathepsin L precursor 0.0542 0.1123 0.1221
Echinococcus granulosus cathepsin L cysteine proteinase 0.2426 0.5188 0.5188
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1209 0.2562 0.4486
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Trypanosoma brucei hypothetical protein 0.0653 0.1363 0.238
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Loa Loa (eye worm) hypothetical protein 0.1608 0.3425 0.3722
Brugia malayi calcium-binding protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Onchocerca volvulus 0.0036 0.0032 0.0053
Entamoeba histolytica grainin 2 0.0124 0.0221 0.0421
Plasmodium vivax vivapain-1 0.1306 0.2771 0.5334
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0064 0.0092 0.0092
Onchocerca volvulus 0.0042 0.0043 0.0075
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.057 0.1183 0.1281
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Brugia malayi GPI-anchor transamidase 0.0035 0.0028 0.0031
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0039 0.0033
Schistosoma mansoni hypothetical protein 0.0099 0.0167 0.0177
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0016 0.0014
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0023 0.0025
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Plasmodium vivax hypothetical protein, conserved 0.0235 0.0461 0.0873
Entamoeba histolytica calcium-binding protein, putative 0.0116 0.0204 0.0387
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.0027 0.0012 0.0015
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Leishmania major receptor-type adenylate cyclase a-like protein 0.0208 0.0403 0.0694
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1209 0.2562 0.2777
Leishmania major META domain containing protein 0.0208 0.0403 0.0694
Toxoplasma gondii proteasome subunit beta type, putative 0.0083 0.0132 0.0238
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0222 0.0242
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0212
Onchocerca volvulus 0.1662 0.354 0.6821
Brugia malayi Peroxidasin 0.0064 0.0092 0.01
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.1461 0.1447
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Onchocerca volvulus 0.0154 0.0286 0.0542
Echinococcus granulosus caspase 2 0.0061 0.0085 0.0085
Giardia lamblia Proteasome subunit beta type 2 0.004 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0024 0.0031
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0216 0.02
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.4874
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0039 0.0042
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0235 0.0461 0.0888
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Plasmodium vivax SET domain protein, putative 0.0122 0.0218 0.0404
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Toxoplasma gondii centrin 0.0116 0.0204 0.0377
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0016 0.0014
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Echinococcus granulosus centrin 2 0.0116 0.0204 0.0204
Brugia malayi hypothetical protein 0.0486 0.1003 0.109
Plasmodium vivax proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Plasmodium vivax unspecified product 0.0764 0.1601 0.3075
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus granulosus Transglutaminase 0.0251 0.0496 0.0496
Echinococcus granulosus prolyl endopeptidase 0.1651 0.3518 0.3518
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0062 0.0063
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0811 0.1705 0.328
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Leishmania major protein kinase, putative 0.0116 0.0204 0.0343
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Schistosoma mansoni rab 0.0116 0.0204 0.0217
Schistosoma mansoni hypothetical protein 0.0061 0.0085 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Onchocerca volvulus 0.0029 0.0016 0.0021
Brugia malayi intermediate filament protein 0.0027 0.0012 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Echinococcus multilocularis histone deacetylase 0.0099 0.0167 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0089 0.0096
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Brugia malayi NAD-dependent deacetylase SIRT1 0.0138 0.0251 0.0273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Echinococcus granulosus calcium uptake protein 1 0.0118 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Plasmodium falciparum serine repeat antigen 6 0.0542 0.1123 0.2152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Mycobacterium tuberculosis Conserved protein 0.0251 0.0496 0.0481
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0039 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Schistosoma mansoni hypothetical protein 0.0389 0.0793 0.0857
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0218 0.0218
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0118 0.0208 0.0221
Toxoplasma gondii EF hand domain-containing protein 0.0116 0.0204 0.0377
Echinococcus granulosus intermediate filament protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.1277
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0022 0.0026
Schistosoma mansoni hypothetical protein 0.0132 0.0239 0.0255
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Leishmania major DNA polymerase eta, putative 0.0045 0.0051 0.0075
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0215 0.02
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0542 0.1123 0.2152
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0039 0.0042
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0764 0.1601 0.174
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Loa Loa (eye worm) calmodulin-like protein 0.0116 0.0204 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) EF hand family protein 0.0116 0.0204 0.0221
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.2718
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0215 0.02
Toxoplasma gondii ABC1 family protein 0.0036 0.0032 0.0046
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.4285 0.9202 1
Brugia malayi Blistered cuticle protein 3 0.0064 0.0092 0.01
Toxoplasma gondii histone deacetylase HDAC1 0.0099 0.0167 0.0306
Plasmodium falciparum serine repeat antigen 5 0.0542 0.1123 0.2152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.2777
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.055 0.114 0.1231
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0235 0.0461 0.0873
Leishmania major small myristoylated protein-2 0.0655 0.1368 0.2389
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0094 0.0103
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Schistosoma mansoni hypothetical protein 0.0052 0.0066 0.0067
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Trypanosoma brucei calpain-like protein, putative 0.1209 0.2562 0.4486
Echinococcus multilocularis cathepsin L 0.0542 0.1123 0.1123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma brucei antigen, putative 0.0944 0.1991 0.3484
Leishmania major centrin, putative,caltractin, putative 0.0116 0.0204 0.0343
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0023 0.0027
Leishmania major proteasome beta 5 subunit, putative 0.0083 0.0132 0.0216
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0028 0.0026
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Onchocerca volvulus Cathepsin L homolog 0.0542 0.1123 0.2158
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.0049
Echinococcus multilocularis cathepsin L 0.1306 0.2771 0.2771
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0116 0.0204 0.0393
Onchocerca volvulus 0.122 0.2585 0.4979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Onchocerca volvulus 0.0132 0.0239 0.0452
Schistosoma mansoni centrin 0.0116 0.0204 0.0217
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.2426 0.5188 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Brugia malayi Kringle domain containing protein 0.0045 0.005 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus granulosus lamin 0.0027 0.0012 0.0012
Onchocerca volvulus 0.0031 0.0019 0.0029
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.2168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Echinococcus granulosus proteasome prosome macropain 0.0083 0.0132 0.0132
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0208 0.0403 0.0694
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0032 0.0016
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0132 0.0239 0.0255
Brugia malayi TAR-binding protein 0.0065 0.0094 0.0103
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Toxoplasma gondii cathepsin CPC1 0.0542 0.1123 0.2152
Echinococcus granulosus calpain 7 C02 family 0.0944 0.1991 0.1991
Onchocerca volvulus 0.0029 0.0016 0.0021
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Plasmodium vivax proteasome subunit beta type-5, putative 0.0083 0.0132 0.0238
Brugia malayi Pre-SET motif family protein 0.0122 0.0218 0.0237
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Brugia malayi hypothetical protein 0.0037 0.0033 0.0035
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0092 0.0169
Giardia lamblia Transglutaminase/protease, putative 0.0251 0.0496 0.1314
Loa Loa (eye worm) hypothetical protein 0.0154 0.0286 0.031
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0208 0.0403 0.0694
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Onchocerca volvulus Deterin homolog 0.0132 0.0239 0.0452
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0019 0.0021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Echinococcus granulosus cathepsin l1 0.2426 0.5188 0.5188
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trichomonas vaginalis calcium binding protein, putative 0.0124 0.0221 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Entamoeba histolytica calpain family cysteine protease, putative 0.0389 0.0793 0.1523
Trypanosoma cruzi major cysteine proteinase, putative 0.0779 0.1634 0.1769
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Loa Loa (eye worm) RGS-3 protein 0.004 0.0039 0.0042
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Onchocerca volvulus Legumain homolog 0.0149 0.0276 0.0524
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Echinococcus granulosus Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0023 0.0027
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0235 0.0461 0.0888
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0456 0.0441
Giardia lamblia Proteasome subunit beta type 1 0.0064 0.0092 0.0193
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0222 0.0423
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0516 0.1067 0.1151
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0143 0.0156
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0116 0.0204 0.0377
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0235 0.0461 0.0496
Trypanosoma cruzi small myristoylated protein 1-1 0.036 0.073 0.0784
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0143 0.0143
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0854 0.1797 0.1952
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0019 0.0019
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.005 0.005
Entamoeba histolytica cysteine proteinase 1, putative 0.1306 0.2771 0.5339
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0016 0.0014
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0167 0.0182
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0039 0.0039
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.057 0.1183 0.1277
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Trichomonas vaginalis calcineurin B subunit, putative 0.0116 0.0204 0.0393
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0039 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Loa Loa (eye worm) papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Brugia malayi calpain D 0.0389 0.0793 0.0861
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0653 0.1363 0.238
Onchocerca volvulus 0.0029 0.0016 0.0021
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0039 0.0037
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma brucei small myristoylated protein 1-2 0.036 0.073 0.1267
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Echinococcus granulosus neuronal calcium sensor 0.0116 0.0204 0.0204
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4285 0.9202 1
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0143 0.0261
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Echinococcus granulosus Glycosyl transferase family 35 0.0105 0.0181 0.0181
Trypanosoma cruzi conserved protein 0.0606 0.1262 0.1363
Trichomonas vaginalis myosin light chain 1, putative 0.0116 0.0204 0.0393
Trichomonas vaginalis calmodulin, putative 0.0118 0.0208 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.0461 0.0888
Plasmodium vivax unspecified product 0.0542 0.1123 0.2152
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.17 0.3622 0.3933
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Trichomonas vaginalis calcineurin B subunit, putative 0.0118 0.0208 0.0402
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0032 0.0016
Echinococcus multilocularis musashi 0.0027 0.0012 0.0012
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.0016 0.0017
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Mycobacterium ulcerans lipase LipD 0.0036 0.0032 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.1342
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Long conserved protein 0.0251 0.0496 0.0481
Brugia malayi Cathepsin L-like precursor 0.0764 0.1601 0.174
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0045 0.0045
Brugia malayi cathepsin B-like cysteine proteinase 0.4285 0.9202 1
Trypanosoma brucei histone deacetylase 3 0.0099 0.0167 0.0278
Brugia malayi prolyl oligopeptidase family protein 0.057 0.1183 0.1285
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 56.4 uM Concentration of the compound required to reduce the viability of uninfected MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 0.04 uM Concentration of the compound required to inhibit human immunodeficiency virus-1 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 0.4 uM Concentration of the compound required to reduce human cytomegalo virus(Davis) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 1.4 uM Concentration of the compound required to reduce human cytomegalo virus(AD-169) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 4.17 uM Concentration of the compound required to inhibit human immunodeficiency virus-2 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) > 22 uM Concentration of the compound required to inhibit HEL cell growth by 50% ChEMBL. 9022801
IC50 (functional) = 45 uM Concentration of the compound required to reduce herpes simplex virus-1TK( B2006) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 45 uM Concentration of the compound required to reduce herpes simplex virus-2(G) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 54.2 uM Concentration of the compound required to inhibit by 50% human immunodeficiency virus-2 induced syncytium formation upon coculturing persistently HIV-infected HUT-78 cells with MOLT-4 cells ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce herpes simplex virus-1TK (VMW1837) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce herpes simplex virus-1TK (KOS) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce vesicular stomatitis virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce Coxsackie virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal E6SM cell morphology ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal Hela cell morphology ChEMBL. 9022801

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9022801

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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