Detailed information for compound 2078153

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 406.397 | Formula: C18H25F3N2O5
  • H donors: 1 H acceptors: 3 LogP: -0.79 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.COCCN1CCC2(C1=O)CCCN(C2)Cc1ccoc1
  • InChi: 1S/C16H24N2O3.C2HF3O2/c1-20-10-8-18-7-5-16(15(18)19)4-2-6-17(13-16)11-14-3-9-21-12-14;3-2(4,5)1(6)7/h3,9,12H,2,4-8,10-11,13H2,1H3;(H,6,7)
  • InChiKey: VUXFKCYXQSTCBH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Regulator of G protein signaling domain containing protein 0.0027 0.0032 0.0075
Echinococcus granulosus smad 0.0035 0.0056 0.0089
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0001 0.0002
Schistosoma mansoni tubulin subunit alpha 0.1137 0.3232 0.516
Brugia malayi regulator of G-protein signaling egl-10 0.0027 0.0032 0.0075
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0102 0.0249 0.0578
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0114 0.0266
Trypanosoma cruzi alpha tubulin, putative 0.1137 0.3232 0.7512
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0035 0.0056
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0024 0.0049
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0083 0.0796
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0131 0.0209
Echinococcus granulosus regulator of G protein signaling 3 0.0027 0.0032 0.0052
Trichomonas vaginalis tubulin alpha chain, putative 0.1509 0.4303 1
Schistosoma mansoni lamin 0.0085 0.02 0.0319
Brugia malayi MH2 domain containing protein 0.0035 0.0056 0.0129
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.0307 0.0714
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.002 0.002
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0378 0.1044 0.2421
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0047 0.0047
Schistosoma mansoni follistatin 0.0065 0.0142 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.011 0.0255
Brugia malayi sodium-independent organic anion transporter family protein 0.0095 0.0229 0.0533
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.002 0.0033
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0759 0.2143 0.4977
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0053 0.0124
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0569 0.1595 0.3706
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0039
Loa Loa (eye worm) follicle stimulating hormone receptor 0.027 0.0733 0.1704
Brugia malayi SPARC precursor 0.0065 0.0142 0.033
Entamoeba histolytica P-glycoprotein-1 0.0024 0.0024 0.0035
Giardia lamblia Gamma tubulin 0.0864 0.2445 0.5674
Brugia malayi jmjC domain containing protein 0.0063 0.0137 0.0319
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0155 0.04 0.0639
Echinococcus granulosus intermediate filament protein 0.0085 0.02 0.0319
Loa Loa (eye worm) hypothetical protein 0.0083 0.0195 0.0454
Leishmania major beta tubulin 0.1509 0.4303 1
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0046 0.01
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.02 0.053 0.1213
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0273 0.0634
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Schistosoma mansoni hypothetical protein 0.0728 0.2054 0.3279
Echinococcus multilocularis Smad4 0.0035 0.0056 0.0056
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0056 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.011 0.0255
Trypanosoma brucei zeta tubulin 0.0697 0.1965 0.4566
Schistosoma mansoni multidrug resistance protein 0.0024 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.005 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.011 0.0255
Plasmodium vivax tubulin beta chain, putative 0.1509 0.4303 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0047 0.0109
Toxoplasma gondii beta-1 tubulin, putative 0.1509 0.4303 1
Trypanosoma brucei alpha tubulin 0.1137 0.3232 0.7512
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0039 0.0062
Brugia malayi hypothetical protein 0.0027 0.0032 0.0075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0156 0.0404 0.0404
Echinococcus granulosus phd:f box containing protein 0.0016 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.0307 0.0707
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0039 0.009
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0114 0.0266
Leishmania major beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0017 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.011 0.0255
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.001 0.0024
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0009 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0083 0.0193
Echinococcus granulosus Smad4 0.0035 0.0056 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.1044 0.2421
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0273 0.0436
Plasmodium falciparum tubulin beta chain 0.1509 0.4303 1
Onchocerca volvulus 0.0103 0.0252 0.105
Brugia malayi jmjC domain containing protein 0.006 0.0128 0.0297
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0064 0.0102
Brugia malayi Nuclear hormone receptor E75 0.0023 0.002 0.0048
Echinococcus multilocularis tubulin epsilon chain 0.0864 0.2444 0.2444
Echinococcus granulosus expressed protein 0.0426 0.1181 0.1886
Giardia lamblia Beta tubulin 0.1509 0.4303 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0054 0.011 0.0255
Leishmania major delta tubulin, putative 0.0569 0.1595 0.3706
Schistosoma mansoni cellular tumor antigen P53 0.0163 0.0424 0.0677
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0111 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Echinococcus granulosus neuropeptide receptor A26 0.0939 0.2662 0.425
Onchocerca volvulus 0.0095 0.0229 0.0949
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0056 0.0089
Giardia lamblia Alpha-tubulin 0.1137 0.3232 0.7507
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0131 0.0131
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0054 0.0111 0.0251
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Schistosoma mansoni hypothetical protein 0.0829 0.2345 0.3743
Brugia malayi tubulin alpha-2 chain 0.1137 0.3232 0.7512
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.011 0.0255
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.005 0.0116
Brugia malayi hypothetical protein 0.0112 0.0278 0.0646
Echinococcus granulosus RUN 0.0112 0.0278 0.0444
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Schistosoma mansoni rab6-interacting 0.0112 0.0278 0.0444
Brugia malayi Tubulin alpha-2 chain 0.1137 0.3232 0.7512
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0024 0.0024
Onchocerca volvulus 0.0155 0.0401 0.1702
Brugia malayi Pax transcription factor protein 2 0.0246 0.0663 0.1542
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0013 0.0121
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0273 0.0634
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0682 0.192 0.4458
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0054 0.0111 0.0251
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0081 0.0189 0.0439
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.011 0.0175
Brugia malayi MH1 domain containing protein 0.0035 0.0056 0.0129
Echinococcus multilocularis tubulin beta 1 chain 0.1509 0.4303 0.4303
Schistosoma mansoni lipoxygenase 0.0255 0.0688 0.1099
Echinococcus granulosus regulator of G protein signaling 3 0.0027 0.0032 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0102 0.0249 0.0578
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0395 0.1094 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Echinococcus granulosus tubulin subunit TubB 0.1137 0.3232 0.516
Echinococcus multilocularis transfer RNA-Lys 0.0155 0.0401 0.0401
Echinococcus multilocularis tubulin subunit beta 0.1509 0.4303 0.4303
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0273 0.0627
Echinococcus multilocularis tubulin alpha 3 chain 0.1137 0.3232 0.3232
Brugia malayi glutathione reductase 0.0156 0.0404 0.0939
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0189 0.0431
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0019 0.001 0.0024
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0024 0.0024
Brugia malayi 6-phosphofructokinase 0.0123 0.0308 0.0716
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0047 0.0109
Loa Loa (eye worm) hypothetical protein 0.1137 0.3232 0.7512
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0065 0.0142 0.033
Brugia malayi nuclear hormone receptor 0.0023 0.002 0.0048
Echinococcus granulosus alpha tubulin 0.1137 0.3232 0.516
Echinococcus multilocularis lamin dm0 0.0085 0.02 0.02
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.002 0.0048
Echinococcus granulosus thioredoxin glutathione reductase 0.0156 0.0404 0.0645
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0122 0.0307 0.281
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0032 0.0052
Echinococcus multilocularis serine protein kinase ATM 0.0019 0.001 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.0307 0.0707
Mycobacterium ulcerans endonuclease IV 0.0077 0.0177 0.1695
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0122 0.0307 0.2881
Plasmodium falciparum tubulin gamma chain 0.0864 0.2445 0.5683
Echinococcus granulosus tubulin alpha 1C chain 0.1137 0.3232 0.516
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.011 0.011
Brugia malayi 6-phosphofructokinase 0.0122 0.0307 0.0714
Echinococcus multilocularis beta tubulin 0.1509 0.4303 0.4303
Loa Loa (eye worm) tubulin alpha chain 0.1137 0.3232 0.7512
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0177 0.1618
Brugia malayi sodium-independent organic anion transporter family protein 0.0095 0.0229 0.0533
Trypanosoma cruzi trypanothione reductase, putative 0.0156 0.0404 0.0939
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0102
Onchocerca volvulus 0.0095 0.0229 0.0949
Trichomonas vaginalis tubulin alpha chain, putative 0.0455 0.1267 0.2939
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0073 0.0117
Echinococcus granulosus lipoxygenase domain containing protein 0.0112 0.0278 0.0444
Leishmania major beta tubulin 0.1509 0.4303 1
Brugia malayi Tubulin alpha chain 0.0378 0.1044 0.2426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Brugia malayi Cytochrome P450 family protein 0.0045 0.0083 0.0193
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.011 0.0255
Echinococcus multilocularis Tubulin beta 2C chain 0.1509 0.4303 0.4303
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.011 0.0255
Leishmania major hypothetical protein, conserved 0.0108 0.0267 0.0621
Plasmodium falciparum glutathione reductase 0.0156 0.0404 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0111 0.0251
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.011 0.0175
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.005 0.0116
Brugia malayi Tubulin gamma chain 0.0864 0.2445 0.5684
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0039 0.0088
Leishmania major beta tubulin 0.1509 0.4303 1
Mycobacterium leprae Possible regulatory protein 0.0054 0.0111 0.1018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.011 0.0257
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.005 0.0114
Echinococcus multilocularis 6 phosphofructokinase 0.0122 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0024
Brugia malayi PXA domain containing protein 0.0027 0.0032 0.0075
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Toxoplasma gondii LsmAD domain-containing protein 0.0108 0.0267 0.0621
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0054 0.011 0.0257
Brugia malayi MH2 domain containing protein 0.0035 0.0056 0.0129
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.011 0.011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0086 0.02
Loa Loa (eye worm) PXA domain-containing protein 0.0027 0.0032 0.0075
Brugia malayi hypothetical protein 0.0108 0.0267 0.0621
Brugia malayi conserved hypotetical protein 0.0023 0.002 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0129 0.0292
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0102 0.0249 0.0558
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0149 0.0347
Echinococcus granulosus lamin 0.0085 0.02 0.0319
Brugia malayi hypothetical protein 0.0155 0.04 0.0931
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0031 0.0044 0.007
Loa Loa (eye worm) tubulin beta chain 0.0378 0.1044 0.2426
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0031
Trypanosoma brucei beta tubulin 0.0833 0.2356 0.5476
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0054 0.011 0.0257
Loa Loa (eye worm) hypothetical protein 0.0682 0.192 0.4462
Echinococcus multilocularis smad 0.0035 0.0056 0.0056
Brugia malayi follicle stimulating hormone receptor 0.027 0.0733 0.1704
Echinococcus granulosus tubulin alpha chain 0.1137 0.3232 0.516
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0065 0.0142 0.033
Echinococcus multilocularis tubulin alpha chain 0.1137 0.3232 0.3232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Echinococcus granulosus beta-adrenergic receptor kinase 0.0028 0.0035 0.0056
Echinococcus multilocularis protein patched 0.0086 0.0202 0.0202
Echinococcus granulosus Tubulin alpha 1 chain 0.1137 0.3232 0.516
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0067 0.0155
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0054 0.011 0.1009
Schistosoma mansoni jun-related protein 0.0147 0.0377 0.0602
Brugia malayi hypothetical protein 0.0027 0.0032 0.0075
Trypanosoma cruzi tubulin gamma chain 0.0864 0.2445 0.5684
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.0024 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.0252 0.0403
Mycobacterium ulcerans cell division protein FtsZ 0.0378 0.1044 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0108 0.0267 0.0621
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0202 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Mycobacterium ulcerans hypothetical protein 0.002 0.0013 0.0126
Schistosoma mansoni thyroid hormone receptor 0.0054 0.011 0.0175
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Schistosoma mansoni rab6-interacting 0.0112 0.0278 0.0444
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0071
Schistosoma mansoni smad 0.0035 0.0056 0.0089
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0064 0.0148
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0067 0.0107
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0024 0.0024
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0025 0.0057
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0356 0.0979 0.8955
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.001 0.0016
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0032 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0064 0.014
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.033
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) MH2 domain-containing protein 0.0513 0.1434 0.3332
Mycobacterium tuberculosis Cell division protein FtsZ 0.0378 0.1044 0.9545
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0065 0.0142 0.033
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.011 0.0255
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) hypothetical protein 0.0263 0.0713 0.1657
Schistosoma mansoni axis inhibition protein axin 0.0027 0.0032 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0273 0.0436
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0075 0.0167
Plasmodium vivax tubulin gamma chain, putative 0.0864 0.2445 0.5683
Leishmania major cytochrome p450-like protein 0.0045 0.0083 0.0193
Trypanosoma brucei beta tubulin 0.1509 0.4303 1
Leishmania major gamma-tubulin 0.0864 0.2445 0.5684
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0027 0.0032 0.0052
Schistosoma mansoni microtubule-associated protein tau 0.2189 0.6265 1
Onchocerca volvulus 0.0054 0.011 0.0423
Echinococcus multilocularis Tubulin beta 2C chain 0.1509 0.4303 0.4303
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.011 0.0255
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0044 0.0102
Entamoeba histolytica hypothetical protein 0.0155 0.04 0.0911
Echinococcus multilocularis Tubulin alpha 1 chain 0.1137 0.3232 0.3232
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.011 0.011
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.001 0.0024
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0112 0.0278 0.0646
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0054 0.0111 0.0178
Trypanosoma brucei beta tubulin 0.1509 0.4303 1
Plasmodium falciparum alpha tubulin 1 0.1137 0.3232 0.7512
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.011 0.0255
Trypanosoma brucei beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Schistosoma mansoni smad1 5 8 and 0.0035 0.0056 0.0089
Echinococcus multilocularis lipoxygenase domain containing protein 0.0112 0.0278 0.0278
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0001 0.0002
Echinococcus multilocularis tubulin alpha 1C chain 0.1137 0.3232 0.3232
Brugia malayi multidrug resistance protein 3 0.0024 0.0024 0.0057
Leishmania major beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0712 0.2007 0.4665
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0356 0.0979 0.8955
Brugia malayi hypothetical protein 0.0023 0.002 0.0048
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0047 0.0109
Plasmodium vivax tubulin alpha chain, putative 0.1137 0.3232 0.7512
Entamoeba histolytica hypothetical protein 0.0027 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0175 0.046 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.001 0.0016
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0056 0.0056
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0156 0.0404 0.3693
Brugia malayi hypothetical protein 0.0031 0.0044 0.0102
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0131 0.1253
Brugia malayi MAP kinase sur-1 0.011 0.0273 0.0634
Schistosoma mansoni nuclear hormone receptor 0.0023 0.002 0.0033
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.0307 0.0714
Schistosoma mansoni zinc finger protein 0.0023 0.002 0.0033
Toxoplasma gondii beta-tubulin, putative 0.1509 0.4303 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0007 0.0007
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0054 0.011 0.1058
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.0307 0.0714
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0046 0.0086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0007 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0129 0.0292
Plasmodium vivax thioredoxin reductase, putative 0.0156 0.0404 0.0937
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0054 0.011 0.0176
Schistosoma mansoni transcription factor LCR-F1 0.0155 0.04 0.0639
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Mycobacterium leprae conserved hypothetical protein 0.002 0.0013 0.0121
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0111 0.0251
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.0024 0.0054
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.0111 0.0111
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.011 0.0423
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.0053 0.0124
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Echinococcus granulosus tubulin delta chain 0.0378 0.1044 0.1666
Schistosoma mansoni cpg binding protein 0.0062 0.0132 0.0211
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0007 0.0012
Schistosoma mansoni hypothetical protein 0.0083 0.0193 0.0308
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Echinococcus multilocularis Regulator of G protein signaling 20 0.0027 0.0032 0.0032
Loa Loa (eye worm) tubulin alpha 2 0.0759 0.2143 0.4981
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0378 0.1044 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0273 0.0634
Brugia malayi steroid hormone receptor 0.0054 0.011 0.0255
Trichomonas vaginalis set domain proteins, putative 0.081 0.229 0.5319
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0273 0.0436
Echinococcus granulosus microtubule associated protein 2 0.2189 0.6265 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.013 0.0296
Brugia malayi PXA domain containing protein 0.0027 0.0032 0.0075
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.0024 0.0054
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0031 0.0044 0.0102
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0131 0.1253
Schistosoma mansoni alpha tubulin 0.1137 0.3232 0.516
Trypanosoma cruzi tubulin delta chain 0.0569 0.1595 0.3706
Echinococcus granulosus single minded 2 0.0155 0.0401 0.064
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.001 0.0017
Brugia malayi nuclear receptor NHR-67 0.0023 0.002 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0252 0.0403
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0095 0.0229 0.0229
Loa Loa (eye worm) glutathione reductase 0.0156 0.0404 0.0939
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0003 0.0005
Toxoplasma gondii alpha-tubulin I, putative 0.1137 0.3232 0.7512
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0079
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0042 0.0077 0.0179
Treponema pallidum NADH oxidase 0.0054 0.011 0.0977
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Brugia malayi ABC transporter family protein 0.0024 0.0024 0.0057
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.011 0.0257
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0002
Giardia lamblia Beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0083 0.0193
Trypanosoma cruzi PAB1-binding protein , putative 0.0108 0.0267 0.0621
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.011 0.011
Brugia malayi hypothetical protein 0.0263 0.0713 0.1657
Loa Loa (eye worm) hypothetical protein 0.0108 0.0267 0.0621
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0013 0.0126
Trichomonas vaginalis tubulin, putative 0.0455 0.1267 0.2939
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0024
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.0024 0.0057
Loa Loa (eye worm) alpha-tubulin 0.1137 0.3232 0.7512
Brugia malayi phosphofructokinase 0.0122 0.0307 0.0714
Loa Loa (eye worm) Smad1 0.0035 0.0056 0.0129
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0001 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0024 0.0039
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Brugia malayi Cell division protein ftsZ 0.0378 0.1044 0.2426
Onchocerca volvulus 0.0112 0.0278 0.1162
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.011 0.0255
Echinococcus granulosus dnaJ subfamily B 0.0829 0.2345 0.3743
Onchocerca volvulus 0.0246 0.0663 0.2855
Trypanosoma cruzi beta tubulin, putative 0.1509 0.4303 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.0307 0.0714
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0024 0.0024
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.0024 0.0035
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0019 0.001 0.0017
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0024 0.0057
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0131 0.1253
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Entamoeba histolytica tubulin alpha-1 chain 0.1137 0.3232 0.7507
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0177 0.0409
Giardia lamblia Alpha-tubulin 0.1137 0.3232 0.7507
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0039 0.0068
Trichomonas vaginalis tubulin epsilon chain, putative 0.1509 0.4303 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.0053 0.0085
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) hypothetical protein 0.0077 0.0177 0.0411
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0064 0.0102
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0024 0.0039
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.005 0.1682
Trichomonas vaginalis abcb9, putative 0.0024 0.0024 0.0049
Echinococcus multilocularis jun protein 0.018 0.0474 0.0474
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.0053 0.0124
Loa Loa (eye worm) hypothetical protein 0.02 0.053 0.1232
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0159
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.011 0.0423
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.004 0.0069 0.0161
Plasmodium vivax glutathione reductase, putative 0.0156 0.0404 0.0937
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.002 0.0033
Brugia malayi MH1 domain containing protein 0.0035 0.0056 0.0129
Trichomonas vaginalis tubulin epsilon chain, putative 0.0378 0.1044 0.2421
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0131 0.0304
Trichomonas vaginalis glutathione reductase, putative 0.0054 0.011 0.0249
Echinococcus granulosus expressed conserved protein 0.0188 0.0495 0.079
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0356 0.0979 0.8955
Echinococcus granulosus Niemann Pick C1 protein 0.0285 0.0777 0.124
Echinococcus granulosus raf serine:threonine protein kinase 0.0049 0.0095 0.0151
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0202 0.0461
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0064 0.0127
Trypanosoma brucei alpha tubulin 0.1137 0.3232 0.7512
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0102 0.0249 0.0249
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0027 0.0032 0.0075
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0149 0.0238
Leishmania major beta tubulin 0.1509 0.4303 1
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.011 0.0423
Trichomonas vaginalis adenylate cyclase, putative 0.0054 0.0111 0.0251
Onchocerca volvulus Huntingtin homolog 0.0263 0.0713 0.3072
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0054 0.011 0.0257
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0047 0.0047
Trichomonas vaginalis tubulin, putative 0.0455 0.1267 0.2939
Brugia malayi tailless protein 0.0023 0.002 0.0048
Echinococcus multilocularis expressed protein 0.0426 0.1181 0.1181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0137 0.0219
Leishmania major beta tubulin 0.1509 0.4303 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0149 0.0347
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0009 0.0022
Echinococcus multilocularis tubulin gamma 1 chain 0.0864 0.2445 0.2445
Echinococcus multilocularis Tubulin alpha 1 chain 0.1137 0.3232 0.3232
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0047 0.0107
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0024 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0053 0.0116
Schistosoma mansoni lipoxygenase 0.0456 0.127 0.2027
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0047 0.0109
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0083 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0114 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0053 0.0116
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0024 0.0049
Echinococcus multilocularis follistatin 0.0065 0.0142 0.0142
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.011 0.0175
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.0053 0.0085
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0148
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0039 0.009
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0039 0.009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.011 0.0175
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.005 0.0114
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.011 0.0175
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.0024 0.0222
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0024 0.0039
Brugia malayi hypothetical protein 0.0031 0.0044 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.013 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0189 0.0431
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0001 0.0001
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0065 0.0142 0.033
Leishmania major beta tubulin 0.1509 0.4303 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0347
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0128 0.0128
Echinococcus multilocularis tubulin alpha chain 0.1137 0.3232 0.3232
Trichomonas vaginalis tubulin alpha chain, putative 0.0455 0.1267 0.2939
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0001 0.0001
Schistosoma mansoni smdr2 0.0024 0.0024 0.0039
Echinococcus granulosus follistatin 0.0065 0.0142 0.0227
Brugia malayi Regulator of G protein signaling domain containing protein 0.0027 0.0032 0.0075
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0024 0.0024 0.0038
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.011 0.0175
Schistosoma mansoni nuclear hormone receptor 0.0054 0.011 0.0175
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.002 0.0048
Leishmania major beta tubulin 0.1509 0.4303 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.011 0.0175
Loa Loa (eye worm) tubulin beta chain 0.1509 0.4303 1
Schistosoma mansoni hypothetical protein 0.0223 0.0598 0.0954
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Echinococcus multilocularis cpg binding protein 0.0062 0.0132 0.0132
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.011 0.011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0064 0.0127
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0027 0.0032 0.0032
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0054 0.011 0.0176
Brugia malayi beta-tubulin, identical 0.1509 0.4303 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0112 0.0278 0.0278
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.002 0.0033
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0202 0.0322
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0114 0.0266
Brugia malayi Cytochrome P450 family protein 0.0045 0.0083 0.0193
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0273 0.0634
Echinococcus granulosus 6 phosphofructokinase 0.0122 0.0307 0.0491
Loa Loa (eye worm) pax transcription factor protein 2 0.0246 0.0663 0.1542
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Brugia malayi MH2 domain containing protein 0.0513 0.1434 0.3332
Leishmania major epsilon tubulin, putative 0.0864 0.2444 0.5681
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0249 0.0571
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0024 0.0039
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0024 0.0035
Loa Loa (eye worm) agrin synaptic family protein 0.0065 0.0142 0.033
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0009 0.0022
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0081 0.0189 0.0439
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0114 0.0256
Echinococcus granulosus tubulin alpha chain 0.1137 0.3232 0.516
Echinococcus granulosus tubulin alpha chain 0.1137 0.3232 0.516
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0273 0.0634
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0095 0.0229 0.0533
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0102 0.0249 0.0397
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0111 0.0259
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.002 0.0048
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0177 0.0411
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.018 0.0474 0.0757
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.0111 0.0259
Giardia lamblia Epsilon tubulin 0.0408 0.1132 0.2615
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0009 0.0022
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Echinococcus multilocularis musashi 0.0085 0.02 0.02
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0054 0.0111 0.5701
Loa Loa (eye worm) tubulin beta-2A chain 0.1509 0.4303 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.001 0.0017
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0131 0.0304
Echinococcus granulosus cpg binding protein 0.0062 0.0132 0.0211
Trichomonas vaginalis tubulin epsilon chain, putative 0.1509 0.4303 1
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.0307 0.0491
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0032 0.0032
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0024
Schistosoma mansoni lamin 0.0085 0.02 0.0319
Echinococcus multilocularis neuropeptide receptor A26 0.0939 0.2662 0.2662
Onchocerca volvulus 0.081 0.2291 1
Schistosoma mansoni hypothetical protein 0.0049 0.0097 0.0154
Echinococcus multilocularis beta tubulin 0.1509 0.4303 0.4303
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0048 0.0094 0.0218
Echinococcus granulosus Tubulin beta 2C chain 0.1509 0.4303 0.6868
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Leishmania major beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) tubulin gamma chain 0.0864 0.2445 0.5684
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0009 0.0014
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0024 0.0049
Schistosoma mansoni tubulin subunit alpha 0.0378 0.1044 0.1666
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0064 0.0064
Loa Loa (eye worm) DR-78 0.0023 0.002 0.0048
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.0053 0.0124
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0003 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0108 0.0267 0.0619
Echinococcus multilocularis tubulin alpha chain 0.1137 0.3232 0.3232
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0075 0.0075
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0054 0.011 0.0255
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0054 0.011 0.0255
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.011 0.0175
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.02 0.0464
Loa Loa (eye worm) alpha-tubulin 0.1137 0.3232 0.7512
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0064 0.0064
Toxoplasma gondii tubulin, putative 0.003 0.0043 0.0099
Brugia malayi CXXC zinc finger family protein 0.0058 0.0123 0.0285
Trichomonas vaginalis tubulin gamma chain, putative 0.0864 0.2445 0.568
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0131 0.0209
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Brugia malayi Doublecortin family protein 0.0112 0.0278 0.0646
Toxoplasma gondii exonuclease III APE 0.0019 0.0009 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0137 0.0319
Trypanosoma cruzi epsilon tubulin, putative 0.0864 0.2444 0.5681
Schistosoma mansoni thyroid hormone receptor 0.0054 0.011 0.0175
Loa Loa (eye worm) phosphofructokinase 0.0122 0.0307 0.0714
Plasmodium vivax ataxin-2 like protein, putative 0.0108 0.0267 0.0619
Treponema pallidum cell division protein FtsZ 0.0378 0.1044 1
Echinococcus granulosus peroxisome assembly protein 26 0.1137 0.3232 0.516
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.1044 0.2421
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0054 0.011 0.0257
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Echinococcus granulosus Solute carrier organic anion transporter family 0.0095 0.0229 0.0366
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.02 0.0464
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.001 0.001
Brugia malayi hypoxia-induced factor 1 0.0647 0.182 0.423
Loa Loa (eye worm) tubulin alpha 2 0.0304 0.0831 0.1931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0053 0.0124
Brugia malayi hypothetical protein 0.007 0.0156 0.0363
Schistosoma mansoni DNA helicase recq5 0.0029 0.0039 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0113 0.0256
Schistosoma mansoni polycystin 1-related 0.0112 0.0278 0.0444
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0007 0.0012
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0148
Leishmania major beta tubulin 0.1509 0.4303 1
Onchocerca volvulus Huntingtin homolog 0.0263 0.0713 0.3072
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0102 0.0249 0.0578
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0064 0.0102
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.005 0.0394
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0019 0.001 0.0003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.011 0.0255
Onchocerca volvulus 0.0085 0.02 0.0819
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0113 0.0256
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.005 0.0116
Echinococcus granulosus geminin 0.0728 0.2054 0.3279
Echinococcus granulosus tubulin beta 4A class IVa 0.1509 0.4303 0.6868
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0027 0.0032 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.011 0.0255
Brugia malayi bHLH-PAS transcription factor 0.0155 0.0401 0.0931
Brugia malayi Tubulin alpha chain 0.1137 0.3232 0.7512
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.002 0.0033
Onchocerca volvulus 0.0023 0.002 0.0032
Trichomonas vaginalis tubulin gamma chain, putative 0.0864 0.2444 0.5677
Echinococcus granulosus neuropeptide s receptor 0.0939 0.2662 0.425
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Schistosoma mansoni hypothetical protein 0.0728 0.2054 0.3279
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0017 0.0017
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0131 0.0209
Loa Loa (eye worm) tubulin alpha chain 0.1137 0.3232 0.7512
Trypanosoma cruzi epsilon tubulin, putative 0.0864 0.2444 0.5681
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0032 0.0052
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0095 0.0151
Schistosoma mansoni loxhd1 0.0112 0.0278 0.0444
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0009 0.0014
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0102 0.0249 0.0558
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0456 0.127 0.127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0114 0.0256
Echinococcus multilocularis peroxisome assembly protein 26 0.1137 0.3232 0.3232
Leishmania major beta tubulin 0.1509 0.4303 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Echinococcus granulosus tubulin alpha 3 chain 0.1137 0.3232 0.516
Echinococcus multilocularis dnaJ subfamily B 0.0829 0.2345 0.2345
Brugia malayi Niemann-Pick C1 protein precursor 0.02 0.053 0.1232
Trichomonas vaginalis tubulin alpha chain, putative 0.0455 0.1267 0.2939
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0001 0.0001
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.002 0.0048
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0028 0.0035 0.0082
Trypanosoma cruzi tubulin delta chain 0.0569 0.1595 0.3706
Trypanosoma brucei tubulin delta chain 0.0569 0.1595 0.3706
Loa Loa (eye worm) tubulin beta-1 chain 0.1509 0.4303 1
Giardia lamblia Delta tubulin 0.0378 0.1044 0.241
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0102
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0075 0.0174
Plasmodium vivax delta tubulin, putative 0.0378 0.1044 0.2425
Trypanosoma brucei protein kinase, putative 0.011 0.0273 0.0634
Echinococcus granulosus Tubulin alpha 1 chain 0.1137 0.3232 0.516
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.011 0.011
Brugia malayi Pre-SET motif family protein 0.0712 0.2007 0.4665
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0053 0.0116
Echinococcus granulosus agrin 0.0065 0.0142 0.0227
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0159
Trypanosoma brucei trypanothione reductase 0.0156 0.0404 0.0939
Schistosoma mansoni organic anion transporter 0.0095 0.0229 0.0366
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.002 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.0307 0.0707
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0083 0.0193
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.011 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.005 0.1682
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.011 0.0175
Echinococcus granulosus Tubulin beta 2C chain 0.1509 0.4303 0.6868
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0027 0.0032 0.0052
Loa Loa (eye worm) tubulin alpha-3 chain 0.0682 0.192 0.4462
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0047 0.0109
Trypanosoma brucei PAB1-binding protein , putative 0.0108 0.0267 0.0621
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0047 0.043
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0047 0.0109
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0114 0.0266
Brugia malayi Smad1 0.0035 0.0056 0.0129
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0095 0.0229 0.0366
Echinococcus multilocularis tubulin alpha 3 chain 0.1137 0.3232 0.3232
Echinococcus granulosus histone lysine methyltransferase setb 0.0103 0.0252 0.0403
Entamoeba histolytica hypothetical protein 0.0155 0.04 0.0911
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0111 0.0251
Leishmania major ATP-dependent phosphofructokinase 0.0122 0.0307 0.0714
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0054 0.011 0.0257
Entamoeba histolytica hypothetical protein 0.0027 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Echinococcus multilocularis tubulin alpha 0.0833 0.2356 0.2356
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.033
Echinococcus granulosus tubulin alpha chain 0.1137 0.3232 0.516
Echinococcus multilocularis Tubulin beta 2C chain 0.1509 0.4303 0.4303
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0123 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0273 0.0627
Plasmodium falciparum thioredoxin reductase 0.0156 0.0404 0.0937
Toxoplasma gondii NADPH-glutathione reductase 0.0054 0.011 0.0257
Trypanosoma cruzi zeta tubulin, putative 0.0697 0.1965 0.4566
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0102 0.0249 0.0578
Echinococcus granulosus lamin dm0 0.0085 0.02 0.0319
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Leishmania major p-glycoprotein 0.0024 0.0024 0.0057
Echinococcus granulosus beta tubulin 0.1509 0.4303 0.6868
Loa Loa (eye worm) transcription factor SMAD2 0.0513 0.1434 0.3332
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0046 0.0107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0086 0.02
Echinococcus granulosus beta tubulin 0.1509 0.4303 0.6868
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0046 0.0107
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0047 0.0047
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0024 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0111 0.0251
Entamoeba histolytica hypothetical protein 0.0027 0.0032 0.0054
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0137 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.0053 0.0053
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) hypothetical protein 0.0163 0.0424 0.0985
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.002 0.0048
Trichomonas vaginalis abcb9, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0122 0.0307 0.281
Echinococcus granulosus Tubulin alpha 1 chain 0.1137 0.3232 0.516
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0058 0.0123 0.048
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.005 0.0095
Echinococcus granulosus Tubulin beta 2C chain 0.1509 0.4303 0.6868
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0017 0.0028
Trypanosoma brucei epsilon tubulin 0.0864 0.2444 0.5681
Echinococcus multilocularis tubulin alpha chain 0.1137 0.3232 0.3232
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0047 0.0075
Trichomonas vaginalis tubulin epsilon chain, putative 0.1137 0.3232 0.7511
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0273 0.0614
Schistosoma mansoni multidrug resistance protein 0.0024 0.0024 0.0039
Trichomonas vaginalis mercuric reductase, putative 0.0054 0.011 0.0249
Echinococcus multilocularis Tubulin beta 2C chain 0.1509 0.4303 0.4303
Schistosoma mansoni hypothetical protein 0.0083 0.0193 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.001 0.0016
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0065 0.0142 0.033
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.005 0.0114
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0177 0.1618
Echinococcus multilocularis expressed protein 0.0065 0.0142 0.0142
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.011 0.0255
Brugia malayi hypothetical protein 0.0023 0.002 0.0048
Echinococcus multilocularis protein dispatched 1 0.0098 0.0237 0.0237
Echinococcus multilocularis expressed conserved protein 0.0188 0.0495 0.0495
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Onchocerca volvulus Putative organic anion transporter 0.0095 0.0229 0.0949
Plasmodium falciparum LCCL domain-containing protein 0.0112 0.0278 0.0644
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0102
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.0083 0.0193 0.0308
Echinococcus granulosus tubulin gamma 1 chain 0.0864 0.2445 0.3904
Schistosoma mansoni intermediate filament proteins 0.0085 0.02 0.0319
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.0024 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.011 0.0255
Onchocerca volvulus 0.0065 0.0142 0.0566
Brugia malayi ecdysone receptor 0.0023 0.002 0.0048
Schistosoma mansoni hypothetical protein 0.0049 0.0095 0.0151
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0131 0.1196
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0103 0.0252 0.0252
Brugia malayi nuclear hormone receptor 0.0054 0.011 0.0255
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0149 0.0149
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.002 0.0048
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0039 0.0039
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.001 0.0017
Loa Loa (eye worm) nuclear factor I 0.0019 0.001 0.0024
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.002 0.0033
Plasmodium vivax tubulin epsilon chain, putative 0.0864 0.2444 0.568
Trypanosoma cruzi zeta tubulin, putative 0.0697 0.1965 0.4566
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0053 0.0124
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0028 0.0035 0.0082
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.0024 0.0035
Loa Loa (eye worm) RGS-3 protein 0.0027 0.0032 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0053 0.0116
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0701 0.1976 0.4594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0146 0.0331
Trichomonas vaginalis tubulin gamma chain, putative 0.0378 0.1044 0.2421
Schistosoma mansoni smad1 5 8 and 0.0035 0.0056 0.0089
Echinococcus multilocularis tubulin alpha chain 0.1137 0.3232 0.3232
Schistosoma mansoni tubulin subunit gamma 0.0864 0.2445 0.3904
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0056 0.0129
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0047 0.0109
Loa Loa (eye worm) hypothetical protein 0.0085 0.02 0.0464
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0111 0.0251
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0073 0.0073
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0202 0.0202
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Toxoplasma gondii alpha tubulin TUBA1 0.1137 0.3232 0.7512
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0102 0.0249 0.0578
Mycobacterium ulcerans 6-phosphofructokinase 0.0122 0.0307 0.2944
Trypanosoma brucei tubulin gamma chain 0.0864 0.2445 0.5684
Entamoeba histolytica hypothetical protein 0.0019 0.001 0.0003
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0024
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0083 0.0193
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0102 0.0249 0.0578
Trichomonas vaginalis tubulin, putative 0.1509 0.4303 1
Loa Loa (eye worm) BEN-1 protein 0.1509 0.4303 1
Onchocerca volvulus 0.0049 0.0097 0.0367
Loa Loa (eye worm) hypothetical protein 0.0103 0.0252 0.0586
Onchocerca volvulus 0.0455 0.1267 0.5505
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0075
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0273 0.0634
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.0307 0.0694
Toxoplasma gondii target of rapamycin (TOR), putative 0.0076 0.0173 0.0403
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0064 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Brugia malayi hypothetical protein 0.0095 0.0229 0.0533
Loa Loa (eye worm) BEN-1 protein 0.1509 0.4303 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0111 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0017 0.0031
Trichomonas vaginalis tubulin beta chain, putative 0.0455 0.1267 0.2939
Toxoplasma gondii endonuclease IV APN 0.0077 0.0177 0.0411
Loa Loa (eye worm) hypothetical protein 0.0041 0.0073 0.017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.011 0.0255
Entamoeba histolytica tubulin alpha chain, putative 0.1137 0.3232 0.7507
Schistosoma mansoni survival motor neuron protein 0.0049 0.0097 0.0154
Schistosoma mansoni tubulin subunit alpha 0.1137 0.3232 0.516
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.011 0.0255
Schistosoma mansoni aryl hydrocarbon receptor 0.0209 0.0557 0.089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.011 0.0255
Leishmania major beta tubulin 0.1509 0.4303 1
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0177 0.0409
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0056 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0053 0.0116
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0064 0.0102
Brugia malayi CHE-14 protein 0.0086 0.0202 0.0469
Brugia malayi intermediate filament protein 0.0085 0.02 0.0464
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0149 0.0347
Brugia malayi Tubulin beta chain 0.0455 0.1267 0.2945
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0007 0.0007
Entamoeba histolytica protein kinase rad3, putative 0.0019 0.001 0.0003
Schistosoma mansoni hypothetical protein 0.0083 0.0193 0.0308
Loa Loa (eye worm) phosphatidylinositol 3 0.0102 0.0249 0.0578
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0032 0.0032
Brugia malayi sodium-independent organic anion transporter family protein 0.0095 0.0229 0.0533
Leishmania major protein kinase, putative 0.0055 0.0114 0.0266
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0024 0.0039
Echinococcus multilocularis Niemann Pick C1 protein 0.0285 0.0777 0.0777
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0273 0.0273
Echinococcus granulosus tubulin beta 1 chain 0.1509 0.4303 0.6868
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.0651 0.1039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0189 0.0431
Brugia malayi hypothetical protein 0.0701 0.1976 0.4594
Onchocerca volvulus Putative organic anion transporter 0.0095 0.0229 0.0949
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.011 0.0255
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.005 0.0095
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0039 0.0062
Loa Loa (eye worm) raf kinase 0.0049 0.0095 0.022
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.0307 0.0694
Loa Loa (eye worm) hypothetical protein 0.0105 0.0257 0.0598
Trypanosoma brucei epsilon tubulin 0.0833 0.2356 0.5476
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0024 0.0049
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0032 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0102
Trichomonas vaginalis taga, putative 0.0024 0.0024 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0252 0.0403
Schistosoma mansoni nuclear hormone receptor 0.0023 0.002 0.0033
Schistosoma mansoni axis inhibition protein axin 0.0027 0.0032 0.0052
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0047 0.0047
Entamoeba histolytica tubulin family protein 0.1509 0.4303 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.002 0.002
Loa Loa (eye worm) thioredoxin reductase 0.0156 0.0404 0.0939
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0273 0.0627
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0002
Brugia malayi Thioredoxin reductase 0.0156 0.0404 0.0939
Plasmodium falciparum ataxin-2 like protein, putative 0.0108 0.0267 0.0619
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0002
Loa Loa (eye worm) tubulin alpha-2 chain 0.1137 0.3232 0.7512
Schistosoma mansoni hypothetical protein 0.0112 0.0278 0.0444
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.011 0.0255
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.001 0.0024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0009 0.0019
Echinococcus multilocularis raf serine:threonine protein kinase 0.0049 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0148
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0103 0.0252 0.0586
Echinococcus granulosus Tubulin beta 2C chain 0.1509 0.4303 0.6868
Schistosoma mansoni z-protein (S1r protein) 0.0027 0.0032 0.0052
Echinococcus granulosus tubulin alpha 3 chain 0.1137 0.3232 0.516
Loa Loa (eye worm) hypothetical protein 0.0242 0.0651 0.1513
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0054 0.011 0.0257
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0095 0.0229 0.0229
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0024 0.0024
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0024 0.0049
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0017 0.0039
Schistosoma mansoni cpg binding protein 0.0062 0.0132 0.0211
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0047 0.0109
Onchocerca volvulus 0.0085 0.02 0.0819
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0111 0.0251
Entamoeba histolytica P-glycoprotein-5 0.0024 0.0024 0.0035
Loa Loa (eye worm) doublecortin family protein 0.0112 0.0278 0.0646
Echinococcus multilocularis geminin 0.0728 0.2054 0.2054
Echinococcus multilocularis tubulin subunit TubB 0.1137 0.3232 0.3232
Schistosoma mansoni tubulin subunit alpha 0.1137 0.3232 0.516
Trypanosoma cruzi target of rapamycin kinase 3 0.0081 0.0189 0.0439
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0395 0.1094 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0469
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.0307 0.0694
Schistosoma mansoni agrin 0.0065 0.0142 0.0227
Echinococcus multilocularis regulator of G protein signaling 3 0.0027 0.0032 0.0032
Schistosoma mansoni alpha tubulin 0.1137 0.3232 0.516
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0001 0.0001
Schistosoma mansoni tubulin subunit beta 0.1509 0.4303 0.6868
Loa Loa (eye worm) intermediate filament protein 0.0085 0.02 0.0464
Leishmania major beta tubulin 0.1509 0.4303 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.011 0.0175
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.0307 0.0707
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.0111 0.0178
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0273 0.0634
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0032 0.0052
Loa Loa (eye worm) hypothetical protein 0.0263 0.0713 0.1657
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.033
Echinococcus granulosus axis inhibition protein axin 0.0027 0.0032 0.0052
Schistosoma mansoni patched 1 0.0086 0.0202 0.0322
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.011 0.0175
Leishmania major protein kinase, putative 0.0055 0.0114 0.0266
Chlamydia trachomatis endonuclease IV 0.0077 0.0177 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0054 0.011 0.5638
Schistosoma mansoni Smad4 0.0035 0.0056 0.0089
Onchocerca volvulus 0.0095 0.0229 0.0949
Entamoeba histolytica hypothetical protein 0.0155 0.04 0.0911
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0273 0.0273
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.011 0.0257
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0064 0.0148
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0054 0.011 0.011
Trypanosoma cruzi MFS transporter, putative 0.0095 0.0229 0.0533
Echinococcus granulosus tubulin epsilon chain 0.0864 0.2444 0.3901
Echinococcus multilocularis Polycystic kidney disease protein 0.0112 0.0278 0.0278
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0097 0.0225
Echinococcus granulosus Polycystic kidney disease protein 0.0112 0.0278 0.0444
Leishmania major beta tubulin 0.1509 0.4303 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0047 0.0047
Trypanosoma brucei epsilon tubulin 0.0864 0.2444 0.5681
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.011 0.0977
Echinococcus multilocularis lamin 0.0085 0.02 0.02
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.011 0.0175
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0189 0.0431
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0009 0.0085
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0103 0.0252 0.0252
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0031 0.0044 0.007
Echinococcus multilocularis agrin 0.0065 0.0142 0.0142
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0128 0.0128
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.011 0.0175
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Trichomonas vaginalis tubulin beta chain, putative 0.1509 0.4303 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0203 0.0539 0.086
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.005 0.0114
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0456 0.127 0.2027
Mycobacterium tuberculosis Probable oxidoreductase 0.0395 0.1094 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.011 0.0977
Schistosoma mansoni alpha tubulin 0.1137 0.3232 0.516
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0273 0.0634
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0032 0.0052
Schistosoma mansoni hypothetical protein 0.0155 0.04 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.013 0.0296
Trypanosoma brucei zeta tubulin, putative 0.0697 0.1965 0.4566
Brugia malayi nuclear receptor NHR-88 0.0054 0.011 0.0255
Leishmania major beta tubulin 0.1509 0.4303 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.011 0.011
Schistosoma mansoni DNA helicase recq1 0.0029 0.0039 0.0062
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0395 0.1094 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0112 0.0278 0.0644
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Echinococcus granulosus tubulin alpha 1C chain 0.1137 0.3232 0.516
Echinococcus granulosus tubulin subunit beta 0.1509 0.4303 0.6868
Loa Loa (eye worm) hypothetical protein 0.0029 0.0039 0.009
Echinococcus multilocularis Niemann Pick C1 protein 0.02 0.053 0.053
Plasmodium falciparum alpha tubulin 2 0.1137 0.3232 0.7512
Toxoplasma gondii FATC domain-containing protein 0.0019 0.001 0.0024
Schistosoma mansoni single-minded 0.0209 0.0557 0.089
Brugia malayi hypothetical protein 0.0112 0.0278 0.0646
Echinococcus granulosus lipoxygenase domain containing protein 0.0112 0.0278 0.0444
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.0053 0.0124
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0001 0.0002
Onchocerca volvulus 0.0095 0.0229 0.0949
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0102
Echinococcus multilocularis RUN 0.0112 0.0278 0.0278
Brugia malayi Tubulin alpha-2 chain 0.1137 0.3232 0.7512
Brugia malayi secreted modular calcium-binding protein 1 0.0065 0.0142 0.033
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0103 0.0252 0.0586
Onchocerca volvulus 0.0024 0.0024 0.0049
Echinococcus granulosus FTZ F1 alpha 0.0054 0.011 0.0175
Entamoeba histolytica tubulin family protein 0.1509 0.4303 1
Brugia malayi isocitrate dehydrogenase 0.0032 0.0047 0.0109
Echinococcus multilocularis hypothetical protein 0.1137 0.3232 0.3232
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0047 0.0109
Brugia malayi Raf kinase 0.0049 0.0095 0.022
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.011 0.0257
Onchocerca volvulus 0.0054 0.0111 0.0431
Brugia malayi nuclear receptor NHR-88 0.0023 0.002 0.0048
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0064 0.0148
Brugia malayi Nuclear hormone receptor E75 0.0023 0.002 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0189 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0152 0.0346
Schistosoma mansoni multidrug resistance protein 0.0024 0.0024 0.0039
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0024 0.0035
Giardia lamblia NADH oxidase lateral transfer candidate 0.0054 0.011 0.0236
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0273 0.0627
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0075 0.0167
Brugia malayi PAS domain containing protein 0.0209 0.0557 0.1295
Echinococcus granulosus Tubulin beta 2C chain 0.1509 0.4303 0.6868
Brugia malayi hypothetical protein 0.0095 0.0229 0.0533
Echinococcus multilocularis neuropeptide s receptor 0.0939 0.2662 0.2662
Trichomonas vaginalis tubulin epsilon chain, putative 0.1137 0.3232 0.7511
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0024 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0028 0.0036 0.0057
Trichomonas vaginalis tubulin, putative 0.0409 0.1133 0.2628
Loa Loa (eye worm) hypothetical protein 0.0112 0.0278 0.0646
Giardia lamblia Beta tubulin 0.1509 0.4303 1
Brugia malayi prostaglandin transporter 0.0095 0.0229 0.0533
Echinococcus granulosus tubulin alpha chain 0.1137 0.3232 0.516
Loa Loa (eye worm) RecQ helicase 0.0042 0.0075 0.0174
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0009 0.0022
Brugia malayi Tubulin beta-1 chain 0.1509 0.4303 1
Schistosoma mansoni nuclear receptor 0.0023 0.002 0.0033
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.002 0.002
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0024 0.0049
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.002 0.0032
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0095 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0173 0.0396
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0026 0.0059
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0031 0.0044 0.0044
Schistosoma mansoni coup transcription factor 0.0054 0.011 0.0175
Echinococcus granulosus jun protein 0.018 0.0474 0.0757
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.011 0.0175
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0102 0.0249 0.0397
Echinococcus granulosus bloom syndrome protein 0.0042 0.0075 0.012
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0001 0.0002
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0065 0.0142 0.033
Echinococcus multilocularis Tubulin beta 2C chain 0.1509 0.4303 0.4303
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0172 0.0274
Trypanosoma brucei alpha tubulin, putative 0.0455 0.1267 0.2945
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0137 0.0219
Echinococcus multilocularis axis inhibition protein axin 0.0027 0.0032 0.0032
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0149 0.0326
Echinococcus granulosus Regulator of G protein signaling 20 0.0027 0.0032 0.0052
Schistosoma mansoni ap endonuclease 0.0019 0.0009 0.0015
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0013 0.0031
Onchocerca volvulus 0.0163 0.0424 0.1804
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.011 0.0257
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Giardia lamblia GTOR 0.0102 0.0249 0.0558
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0283 0.0659
Echinococcus granulosus tumor protein p63 0.1112 0.3161 0.5046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0155 0.04 0.04
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0356 0.0979 0.8955
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.011 0.0175
Echinococcus multilocularis tubulin alpha 1C chain 0.1137 0.3232 0.3232
Brugia malayi hypothetical protein 0.0142 0.0363 0.0843
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0347
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0024 0.0049
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0065 0.0142 0.033
Brugia malayi alpha-tubulin 0.1137 0.3232 0.7512
Plasmodium falciparum thioredoxin reductase 0.0054 0.011 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0068
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.011 0.0175
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0113 0.0256
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Onchocerca volvulus 0.0023 0.002 0.0032
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0027 0.0032 0.0052
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.0024 0.0035
Schistosoma mansoni nuclear receptor 0.0023 0.002 0.0033
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0229 0.0533
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.002 0.002
Brugia malayi ecdysteroid receptor 0.0054 0.011 0.0255
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0022 0.0017 0.0039
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0065 0.0142 0.033
Echinococcus multilocularis regulator of G protein signaling 0.0027 0.0032 0.0032
Schistosoma mansoni tubulin subunit beta 0.0378 0.1044 0.1666
Trichomonas vaginalis abcb9, putative 0.0024 0.0024 0.0049
Plasmodium vivax SET domain protein, putative 0.0103 0.0252 0.0584
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1509 0.4303 0.4303
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.011 0.0255
Echinococcus multilocularis tumor protein p63 0.1112 0.3161 0.3161
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0057
Toxoplasma gondii beta tubulin 0.1509 0.4303 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0103 0.0252 0.0403
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0833 0.2356 0.5476
Schistosoma mansoni tubulin subunit epsilon 0.0864 0.2444 0.3901
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0408 0.1132 0.2631
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0001 0.0001
Brugia malayi A-kinase anchor protein 10, precursor 0.0027 0.0032 0.0075
Mycobacterium tuberculosis Probable dehydrogenase 0.0356 0.0979 0.8955
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0273 0.0634
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0102 0.0249 0.0578
Loa Loa (eye worm) hypoxia-induced factor 1 0.0647 0.182 0.423
Plasmodium falciparum tubulin epsilon chain, putative 0.0864 0.2444 0.568
Schistosoma mansoni cpg binding protein 0.0058 0.0123 0.0196
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0083 0.0193
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0032 0.0051
Brugia malayi regulator of G-protein signaling rgs-7 0.0027 0.0032 0.0075
Brugia malayi tubulin alpha chain - mouse 0.1137 0.3232 0.7512
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0054 0.011 0.1058
Mycobacterium ulcerans epimerase 0.002 0.0013 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.011 0.0257
Echinococcus multilocularis axis inhibition protein axin 0.0027 0.0032 0.0032
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0172 0.0172
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0111 0.0259
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.011 0.0255
Trichomonas vaginalis tubulin alpha chain, putative 0.0833 0.2356 0.5473
Loa Loa (eye worm) hypothetical protein 0.0759 0.2143 0.4981
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0249 0.0571
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0001 0.0001
Loa Loa (eye worm) beta-tubulin 0.1509 0.4303 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0009 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0064 0.014
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0759 0.2143 0.4981
Onchocerca volvulus 0.0095 0.0229 0.0949
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0044 0.007
Plasmodium falciparum glutathione reductase 0.0054 0.011 0.0255
Schistosoma mansoni jumonji domain containing protein 0.006 0.0128 0.0204
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0002
Brugia malayi Tubulin beta chain 0.0378 0.1044 0.2426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0114 0.0256
Loa Loa (eye worm) tubulin beta-4 chain 0.1509 0.4303 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.002 0.0048
Schistosoma mansoni organic anion transporter 0.0095 0.0229 0.0366
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.0024 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Toxoplasma gondii transporter, major facilitator family protein 0.0095 0.0229 0.0533
Schistosoma mansoni tubulin subunit delta 0.0378 0.1044 0.1666
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.0307 0.0491
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.011 0.0175
Trypanosoma brucei alpha tubulin 0.1137 0.3232 0.7512
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0024 0.0039
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0009 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0035 0.0056
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0111 0.0259
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.004 0.0069 0.0161
Echinococcus multilocularis microtubule associated protein 2 0.2189 0.6265 0.6265
Echinococcus granulosus serine protein kinase ATM 0.0019 0.001 0.0017
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0039 0.009
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0255
Entamoeba histolytica tubulin gamma chain 0.0864 0.2445 0.5674
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.002 0.002
Brugia malayi nuclear receptor RXR 0.0023 0.002 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0206 0.0471
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.005 0.0109
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1137 0.3232 0.7511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0249 0.0571
Leishmania major trypanothione reductase 0.0156 0.0404 0.0939
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0024 0.0024
Mycobacterium tuberculosis Probable reductase 0.0356 0.0979 0.8955
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.002 0.0033
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0065 0.0142 0.033
Trichomonas vaginalis tubulin gamma chain, putative 0.1509 0.4303 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0024 0.0049
Echinococcus granulosus tubulin alpha 0.0833 0.2356 0.3761
Brugia malayi hypothetical protein 0.0242 0.0651 0.1513
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0054 0.011 0.0255
Schistosoma mansoni ap endonuclease 0.0019 0.0009 0.0015
Leishmania major beta tubulin 0.1509 0.4303 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0054 0.0111 0.0111
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0056 0.0089
Onchocerca volvulus Putative organic anion transporter 0.0095 0.0229 0.0949
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.002 0.0033
Trichomonas vaginalis tubulin beta chain, putative 0.1137 0.3232 0.7511
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0044 0.0102
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0347
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0057
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0027 0.0032 0.0052
Leishmania major alpha tubulin 0.1137 0.3232 0.7512
Leishmania major zeta tubulin, putative 0.0697 0.1965 0.4566
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0054 0.011 0.1058
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0047 0.0107
Echinococcus granulosus Niemann Pick C1 protein 0.02 0.053 0.0846
Leishmania major beta tubulin 0.1509 0.4303 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0064 0.0102
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.002 0.0032
Brugia malayi bZIP transcription factor family protein 0.018 0.0474 0.1103
Mycobacterium ulcerans putative regulatory protein 0.0155 0.0401 0.3839
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0111 0.0251
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.018 0.0474 0.0474
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0028 0.0035 0.0082
Trypanosoma brucei beta tubulin 0.1509 0.4303 1
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.0651 0.0651
Echinococcus multilocularis beta adrenergic receptor kinase 0.0028 0.0035 0.0035
Toxoplasma gondii thioredoxin reductase 0.0156 0.0404 0.0939
Echinococcus multilocularis regulator of G protein signaling 3 0.0027 0.0032 0.0032
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0128 0.0204
Mycobacterium leprae cell division protein FtsZ 0.0378 0.1044 0.9545
Onchocerca volvulus 0.0112 0.0278 0.1162
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0024 0.0049
Onchocerca volvulus 0.0142 0.0363 0.1535
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0035 0.0056
Toxoplasma gondii protease inhibitor PI2 0.0065 0.0142 0.033
Brugia malayi nuclear receptor RXR 0.0031 0.0044 0.0102
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0356 0.0979 0.8955
Trypanosoma brucei alpha tubulin 0.1137 0.3232 0.7512
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.011 0.0255
Echinococcus multilocularis tubulin delta chain 0.0378 0.1044 0.1044
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0046 0.0107
Schistosoma mansoni smad1 5 8 and 0.0035 0.0056 0.0089
Plasmodium falciparum tubulin delta chain, putative 0.0378 0.1044 0.2425
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0202 0.0469
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0238 0.038
Plasmodium vivax tubulin alpha chain, putative 0.1137 0.3232 0.7512
Schistosoma mansoni hypothetical protein 0.0147 0.0377 0.0602
Echinococcus granulosus axis inhibition protein axin 0.0027 0.0032 0.0052
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0455 0.1267 0.2939
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0056 0.0129
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0322 0.0513
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0149 0.0238
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0039 0.009
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0002
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0047 0.0075
Entamoeba histolytica hypothetical protein 0.0155 0.04 0.0911
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.0053 0.0124
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0095 0.0151
Echinococcus multilocularis Tubulin alpha 1 chain 0.1137 0.3232 0.3232
Loa Loa (eye worm) tubulin alpha 2 0.0759 0.2143 0.4981

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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