Detailed information for compound 2193343

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 318.183 | Formula: C19H26O4
  • H donors: 1 H acceptors: 3 LogP: 2.91 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 0
  • SMILES: O=C1OC[C@@]2([C@@H](C1)[C@@H]1CCC3=C(O)C(=O)CC[C@@]3([C@H]1CC2)C)C
  • InChi: InChI=1S/C19H26O4/c1-18-7-5-12-11(14(18)9-16(21)23-10-18)3-4-13-17(22)15(20)6-8-19(12,13)2/h11-12,14,22H,3-10H2,1-2H3/t11-,12+,14+,18-,19-/m1/s1
  • InChiKey: XRMAJOGFEAYBBA-NQJHRMQHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0085 0.0191
Leishmania major beta tubulin 0.035 0.424 1
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0107 0.1174 0.266
Schistosoma mansoni hypothetical protein 0.0021 0.0085 0.0098
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0085 0.006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Entamoeba histolytica hypothetical protein 0.0106 0.116 0.264
Echinococcus multilocularis neuropeptide s receptor 0.0478 0.5861 0.585
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.1184 1
Mycobacterium ulcerans thymidylate synthase 0.0107 0.1168 0.9865
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Echinococcus granulosus thymidylate synthase 0.0107 0.1168 0.1871
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.1037 0.2349
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0051 0.0097
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0271 0.0918
Plasmodium falciparum tubulin epsilon chain, putative 0.02 0.2349 0.5514
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1184 0.2681
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0051 0.0097
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.1184 0.2749
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Echinococcus granulosus Tubulin beta 2C chain 0.035 0.424 0.6899
Mycobacterium leprae conserved hypothetical protein 0.002 0.0072 0.0168
Schistosoma mansoni zinc finger protein 0.0045 0.0394 0.0604
Loa Loa (eye worm) CBP-B 0.0074 0.0747 0.1693
Echinococcus granulosus tubulin alpha chain 0.0266 0.3177 0.5159
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.116 0.1858
Echinococcus multilocularis Tubulin beta 2C chain 0.035 0.424 0.4226
Echinococcus multilocularis lamin dm0 0.0027 0.0158 0.0133
Trichomonas vaginalis tubulin gamma chain, putative 0.02 0.2349 0.554
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0055 0.0072
Brugia malayi tailless protein 0.0045 0.0394 0.0891
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0085 0.0098
Echinococcus granulosus tubulin alpha chain 0.0266 0.3177 0.5159
Schistosoma mansoni opsin-like receptor 0.0021 0.0085 0.0098
Plasmodium falciparum flap endonuclease 1 0.0026 0.0146 0.0288
Leishmania major beta tubulin 0.035 0.424 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0462 0.0716
Loa Loa (eye worm) cytochrome P450 0.0018 0.0051 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0393 0.0603
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0096 0.1037 0.2349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.015 0.1718 0.4017
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Schistosoma mansoni chromobox protein 0.0069 0.0694 0.1095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi nuclear receptor NHR-88 0.0096 0.1037 0.2349
Echinococcus granulosus neuropeptide receptor 0.0021 0.0085 0.0098
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0113 0.1251 0.2949
Echinococcus multilocularis muscleblind protein 1 0.0148 0.1694 0.1674
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.044 0.068
Brugia malayi Serotonin receptor 0.0021 0.0085 0.0191
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0135 0.0263
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.02 0.2349 0.5514
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0085 0.0098
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0085 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.1037 0.2349
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.1037 0.1015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0376 0.0576
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.1588 0.2558
Trichomonas vaginalis esterase, putative 0.0036 0.0271 0.0639
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1184 0.2749
Echinococcus multilocularis Tubulin beta 2C chain 0.035 0.424 0.4226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0394 0.0604
Echinococcus granulosus allatostatin A receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0096 0.1037 0.2223
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0781 0.1795
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0179 0.2078 0.4901
Echinococcus multilocularis tubulin alpha chain 0.0266 0.3177 0.316
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi phosphofructokinase 0.0108 0.1184 0.2681
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.1709 0.3872
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0055 0.013
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0271 0.173
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0394 0.0891
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0085 0.006
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0161 0.1173
Trypanosoma brucei alpha tubulin 0.0266 0.3177 0.7477
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0639
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0044 0.0369 0.2971
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Schistosoma mansoni Smad4 0.0024 0.0122 0.016
Echinococcus granulosus lamin dm0 0.0027 0.0158 0.0217
Loa Loa (eye worm) tubulin beta-1 chain 0.035 0.424 0.9607
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0918 0.2164
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0072 0.0409
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1324 0.4845
Brugia malayi follicle stimulating hormone receptor 0.025 0.2973 0.6735
Leishmania major beta tubulin 0.035 0.424 1
Plasmodium falciparum tubulin gamma chain 0.02 0.2349 0.5514
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0087 0.0918 0.2164
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0055 0.0124
Loa Loa (eye worm) hypothetical protein 0.0266 0.3177 0.7198
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi ORL1-like opioid receptor 0.0021 0.0085 0.0191
Mycobacterium leprae Probable lipase LipE 0.0036 0.0271 0.173
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0085 0.006
Schistosoma mansoni jun-related protein 0.0068 0.0676 0.1066
Schistosoma mansoni steroid hormone receptor ad4bp 0.0096 0.1037 0.1657
Echinococcus multilocularis beta tubulin 0.035 0.424 0.4226
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0202 0.029
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.14 0.225
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0055 0.013
Echinococcus granulosus CREB binding protein 0.0066 0.0648 0.1021
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0051 0.0224
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1047
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0085 0.0098
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0051 0.0224
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0051 0.0224
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0051 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2801 0.6606
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0158 0.0356
Echinococcus granulosus geminin 0.05 0.6135 1
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0085 0.0098
Echinococcus granulosus somatostatin receptor 0.0021 0.0085 0.0098
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0781 0.2821
Schistosoma mansoni hypothetical protein 0.0051 0.0468 0.0726
Plasmodium vivax tubulin gamma chain, putative 0.02 0.2349 0.5514
Brugia malayi neuropeptide F receptor 0.0021 0.0085 0.0191
Trichomonas vaginalis tubulin alpha chain, putative 0.035 0.424 1
Trypanosoma brucei epsilon tubulin 0.02 0.2349 0.5514
Plasmodium vivax tubulin epsilon chain, putative 0.02 0.2349 0.5514
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0271 0.0247
Leishmania major cytochrome p450-like protein 0.0018 0.0051 0.0062
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.1661 0.164
Giardia lamblia Beta tubulin 0.035 0.424 1
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0309 0.0729
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0188 0.0317
Schistosoma mansoni dihydrofolate reductase 0.0044 0.0369 0.0564
Echinococcus multilocularis cpg binding protein 0.003 0.02 0.0176
Loa Loa (eye worm) thymidylate synthase 0.0107 0.1168 0.2646
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0202 0.0177
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0781 0.1795
Brugia malayi nuclear receptor NHR-88 0.0045 0.0394 0.0891
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0085 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0055 0.0072
Schistosoma mansoni hypothetical protein 0.0018 0.0051 0.0043
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0051 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0051 0.0097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0135 0.0306
Leishmania major beta tubulin 0.035 0.424 1
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0085 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0393 0.0603
Leishmania major dihydrofolate reductase-thymidylate synthase 0.015 0.1718 0.4017
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0085 0.006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0394 0.0891
Trichomonas vaginalis tubulin beta chain, putative 0.035 0.424 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0393 0.0603
Brugia malayi nuclear hormone receptor 0.0045 0.0394 0.0891
Loa Loa (eye worm) Smad1 0.0024 0.0122 0.0276
Schistosoma mansoni tyrosine kinase 0.0306 0.3684 0.5988
Echinococcus multilocularis Smad4 0.0024 0.0122 0.0098
Trypanosoma cruzi zeta tubulin, putative 0.0087 0.0918 0.2118
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0188 0.1406
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0394 0.0891
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0051 0.0097
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0408 0.0627
Toxoplasma gondii ABC1 family protein 0.0036 0.0271 0.0584
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0135 0.0263
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0051 0.0097
Brugia malayi neuropeptide F receptor 0.0021 0.0085 0.0191
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0146 0.0122
Schistosoma mansoni hypothetical protein 0.0068 0.0676 0.1066
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0122 0.0098
Schistosoma mansoni tubulin subunit alpha 0.0266 0.3177 0.5159
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.015 0.1718 0.4017
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0051 0.0097
Echinococcus granulosus tubulin subunit beta 0.035 0.424 0.6899
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0694 0.1571
Echinococcus granulosus tubulin alpha 1C chain 0.0266 0.3177 0.5159
Echinococcus multilocularis Tubulin alpha 1 chain 0.0266 0.3177 0.316
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1173 0.4282
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0051 0.0097
Schistosoma mansoni opsin-like receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0309 0.0546
Schistosoma mansoni cpg binding protein 0.003 0.02 0.0287
Echinococcus granulosus tubulin alpha 3 chain 0.0266 0.3177 0.5159
Echinococcus granulosus CREB binding protein 0.0017 0.0028 0.0005
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0394 0.0604
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0051 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0271 0.0639
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0583 0.1324
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0085 0.0029
Schistosoma mansoni cytochrome P450 0.0018 0.0051 0.0043
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.046
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.1184 0.4321
Brugia malayi photoreceptor-specific nuclear receptor 0.0096 0.1037 0.2349
Entamoeba histolytica tubulin alpha chain, putative 0.0266 0.3177 0.7459
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0051 0.0224
Mycobacterium ulcerans endonuclease IV 0.0076 0.0781 0.6528
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0096 0.1037 0.1657
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0918
Loa Loa (eye worm) alpha-tubulin 0.0266 0.3177 0.7198
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0025 0.0058
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0107 0.1168 0.4263
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0085 0.006
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0188 0.0387
Trypanosoma brucei alpha tubulin 0.0266 0.3177 0.7477
Brugia malayi hypothetical protein 0.0045 0.0394 0.0891
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.1037 0.2349
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0393 0.0603
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0162
Schistosoma mansoni tyrosine kinase 0.0163 0.1874 0.3026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Echinococcus granulosus Tubulin beta 2C chain 0.035 0.424 0.6899
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1173 0.4282
Echinococcus multilocularis Tubulin beta 2C chain 0.035 0.424 0.4226
Echinococcus multilocularis tubulin epsilon chain 0.02 0.2349 0.233
Trypanosoma brucei beta tubulin 0.035 0.424 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0146 0.0288
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus multilocularis 0.0095 0.1015 0.0993
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0098 0.1054 0.1684
Onchocerca volvulus 0.0045 0.0394 0.0741
Echinococcus granulosus muscleblind protein 0.0148 0.1694 0.2733
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0639
Onchocerca volvulus 0.0021 0.0085 0.0029
Brugia malayi Pax transcription factor protein 2 0.0239 0.2841 0.6436
Echinococcus granulosus orexin receptor type 2 0.0021 0.0085 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0096 0.1037 0.2349
Trypanosoma brucei beta tubulin 0.035 0.424 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0202 0.029
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0376 0.0888
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0085 0.0098
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0408 0.0627
Echinococcus multilocularis tubulin delta chain 0.0087 0.0918 0.0895
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0639
Echinococcus granulosus tubulin alpha 3 chain 0.0266 0.3177 0.5159
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0188 0.0387
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0413 0.092
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0918 0.2164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0393 0.0603
Trypanosoma brucei alpha tubulin 0.0266 0.3177 0.7477
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0096 0.1037 0.1015
Trichomonas vaginalis tubulin epsilon chain, putative 0.0266 0.3177 0.7492
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0188 0.0387
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0051 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Toxoplasma gondii beta tubulin 0.035 0.424 1
Toxoplasma gondii alpha tubulin TUBA1 0.0266 0.3177 0.7477
Echinococcus multilocularis muscleblind protein 0.0148 0.1694 0.1674
Loa Loa (eye worm) TK/EGFR protein kinase 0.0306 0.3684 0.8346
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0085 0.0191
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0462 0.1047
Echinococcus granulosus hypothetical protein 0.0021 0.0085 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1173 0.4282
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0085 0.0098
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0107 0.1168 0.8773
Loa Loa (eye worm) BEN-1 protein 0.035 0.424 0.9607
Brugia malayi nuclear receptor RXR 0.0051 0.0462 0.1047
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0055 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Toxoplasma gondii beta-tubulin, putative 0.035 0.424 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0087 0.0918 0.2164
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0085 0.0191
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1184 0.2681
Brugia malayi beta-lactamase 0.0036 0.0271 0.0613
Brugia malayi Tubulin alpha-2 chain 0.0266 0.3177 0.7198
Brugia malayi Smad1 0.0024 0.0122 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0096 0.1037 0.2349
Echinococcus granulosus tubulin epsilon chain 0.02 0.2349 0.3804
Giardia lamblia Alpha-tubulin 0.0266 0.3177 0.7477
Onchocerca volvulus 0.0021 0.0085 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0085 0.0098
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0408 0.0909
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0394 0.037
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus granulosus CREB binding protein 0.0017 0.0028 0.0005
Entamoeba histolytica hypothetical protein 0.0106 0.116 0.264
Echinococcus granulosus CREB binding protein 0.0104 0.1136 0.1819
Brugia malayi hypothetical protein 0.0051 0.0461 0.1043
Trypanosoma cruzi zeta tubulin, putative 0.0087 0.0918 0.2118
Echinococcus multilocularis 0.0018 0.0051 0.0026
Echinococcus granulosus beta tubulin 0.035 0.424 0.6899
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0096 0.1037 0.2349
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0271 0.0918
Echinococcus granulosus tubulin alpha chain 0.0266 0.3177 0.5159
Treponema pallidum cell division protein FtsZ 0.0087 0.0918 0.7704
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.1037 0.2349
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0347 0.0817
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0085 0.0191
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0161 0.0323
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0413 0.0389
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1047
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0085 0.0191
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0188 0.0387
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.1184 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0135 0.0263
Loa Loa (eye worm) pax transcription factor protein 2 0.0239 0.2841 0.6436
Echinococcus granulosus chromobox protein 1 0.0069 0.0694 0.1095
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0096 0.1037 0.1015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0403
Echinococcus multilocularis musashi 0.0027 0.0158 0.0133
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi Tubulin beta chain 0.0087 0.0918 0.2078
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0096 0.1037 0.1657
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0436 0.0674
Loa Loa (eye worm) hypothetical protein 0.0148 0.1694 0.3839
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Plasmodium vivax glutathione reductase, putative 0.0047 0.0413 0.092
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0188 0.0387
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0096 0.1037 0.1657
Brugia malayi CXXC zinc finger family protein 0.0029 0.018 0.0406
Trypanosoma brucei zeta tubulin 0.0087 0.0918 0.2118
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0271 0.0613
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Brugia malayi p25-alpha family protein 0.0364 0.4414 1
Leishmania major beta tubulin 0.035 0.424 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0408 0.0909
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0394 0.0604
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0085 0.006
Echinococcus granulosus intermediate filament protein 0.0027 0.0158 0.0217
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1173 0.4282
Schistosoma mansoni lamin 0.0027 0.0158 0.0217
Schistosoma mansoni tubulin subunit alpha 0.0266 0.3177 0.5159
Brugia malayi hypothetical protein 0.0025 0.0135 0.0306
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Schistosoma mansoni amine GPCR 0.0021 0.0085 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Schistosoma mansoni neuropeptide receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.4269 0.9672
Loa Loa (eye worm) hypothetical protein 0.0047 0.0416 0.0943
Schistosoma mansoni RAR-like nuclear receptor 0.0096 0.1037 0.1657
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0394 0.0891
Brugia malayi Tubulin alpha chain 0.0087 0.0918 0.2078
Brugia malayi MH1 domain containing protein 0.0024 0.0122 0.0276
Giardia lamblia Beta tubulin 0.035 0.424 1
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.015 0.1718 0.4017
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0085 0.006
Mycobacterium ulcerans cell division protein FtsZ 0.0087 0.0918 0.7704
Echinococcus granulosus tubulin beta 1 chain 0.035 0.424 0.6899
Echinococcus multilocularis jun protein 0.0083 0.0873 0.0851
Schistosoma mansoni smad1 5 8 and 0.0024 0.0122 0.016
Echinococcus multilocularis tubulin alpha 3 chain 0.0266 0.3177 0.316
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0408 0.0384
Echinococcus multilocularis CREB binding protein 0.0017 0.0028 0.0003
Loa Loa (eye worm) tubulin alpha-3 chain 0.0153 0.1745 0.3954
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0161 0.0363
Trichomonas vaginalis tubulin gamma chain, putative 0.035 0.424 1
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0085 0.006
Echinococcus multilocularis chromobox protein 1 0.0069 0.0694 0.0671
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0025 0.0058
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0096 0.1037 0.1657
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0135 0.0263
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0051 0.0224
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0161 0.0363
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0462 0.0716
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0044 0.0103
Trypanosoma brucei zeta tubulin, putative 0.0087 0.0918 0.2118
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Onchocerca volvulus 0.0021 0.0085 0.0029
Giardia lamblia Epsilon tubulin 0.0087 0.0918 0.2118
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.244 0.5528
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0055 0.0113
Brugia malayi Thioredoxin reductase 0.0047 0.0413 0.0934
Brugia malayi Heterochromatin protein 1 0.0069 0.0694 0.1571
Schistosoma mansoni nuclear receptor 0.0045 0.0394 0.0604
Schistosoma mansoni tyrosine kinase 0.0163 0.1874 0.3026
Brugia malayi PAS domain containing protein 0.0048 0.043 0.0973
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1047
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0085 0.0191
Loa Loa (eye worm) phosphofructokinase 0.0108 0.1184 0.2681
Loa Loa (eye worm) glutathione reductase 0.0047 0.0413 0.0934
Giardia lamblia Gamma tubulin 0.02 0.2349 0.5514
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Onchocerca volvulus 0.0021 0.0085 0.0029
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.1184 0.8896
Brugia malayi Cell division protein ftsZ 0.0087 0.0918 0.2078
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0085 0.006
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0347 0.0817
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0694 0.1636
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0462 0.0716
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.1037 0.1657
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0085 0.0098
Echinococcus granulosus transcription factor eb 0.0107 0.1174 0.1881
Echinococcus granulosus chromobox protein 1 0.0069 0.0694 0.1095
Echinococcus granulosus Tubulin alpha 1 chain 0.0266 0.3177 0.5159
Onchocerca volvulus 0.0021 0.0085 0.0029
Brugia malayi Cytochrome P450 family protein 0.0018 0.0051 0.0114
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0271 0.2125
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0613
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0394 0.037
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0085 0.006
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0271 0.2125
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0408 0.0909
Leishmania major hypothetical protein, conserved 0.0025 0.0135 0.0263
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0051 0.0097
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0408 0.0923
Onchocerca volvulus 0.0239 0.2841 0.6377
Echinococcus granulosus tumor protein p63 0.0336 0.4061 0.6606
Echinococcus multilocularis hypothetical protein 0.0266 0.3177 0.316
Echinococcus multilocularis CREB binding protein 0.0017 0.0028 0.0003
Schistosoma mansoni opsin-like receptor 0.0021 0.0085 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0345 0.0524
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Brugia malayi alpha-tubulin 0.0266 0.3177 0.7198
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0096 0.1037 0.2349
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0051 0.0224
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0408 0.0384
Schistosoma mansoni hypothetical protein 0.0021 0.0085 0.0098
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0394 0.0604
Trypanosoma cruzi tubulin delta chain 0.0087 0.0918 0.2118
Loa Loa (eye worm) tubulin beta-2A chain 0.035 0.424 0.9607
Brugia malayi glutathione reductase 0.0047 0.0413 0.0934
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0188 0.2154
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0085 0.006
Loa Loa (eye worm) alpha-tubulin 0.0266 0.3177 0.7198
Echinococcus multilocularis tubulin, beta 4A class IVa 0.035 0.424 0.4226
Echinococcus granulosus alpha tubulin 0.0266 0.3177 0.5159
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0085 0.0098
Loa Loa (eye worm) follicle stimulating hormone receptor 0.025 0.2973 0.6735
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0266 0.3177 0.7492
Trichomonas vaginalis tubulin, putative 0.0113 0.1251 0.2949
Brugia malayi Serotonin receptor 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0051 0.0097
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0085 0.0098
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0394 0.0604
Trichomonas vaginalis tubulin gamma chain, putative 0.02 0.2349 0.554
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Echinococcus multilocularis beta tubulin 0.035 0.424 0.4226
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0096 0.1037 0.1657
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0781 0.177
Brugia malayi G-protein coupled receptor 0.0021 0.0085 0.0191
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0161 0.0323
Loa Loa (eye worm) hypothetical protein 0.0049 0.044 0.0996
Echinococcus granulosus g protein coupled receptor 0.0021 0.0085 0.0098
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0408 0.0909
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0085 0.0098
Echinococcus granulosus epidermal growth factor receptor 0.0306 0.3684 0.5988
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0044 0.0103
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0085 0.0191
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0051 0.0224
Leishmania major beta tubulin 0.035 0.424 1
Schistosoma mansoni nuclear receptor 0.0045 0.0394 0.0604
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0055 0.034
Brugia malayi bZIP transcription factor family protein 0.0083 0.0873 0.1978
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus multilocularis somatostatin receptor 0.0021 0.0085 0.006
Trypanosoma brucei beta tubulin 0.02 0.2349 0.5514
Echinococcus multilocularis tubulin alpha 1C chain 0.0266 0.3177 0.316
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0085 0.0098
Echinococcus multilocularis tubulin alpha 0.02 0.2349 0.233
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0271 0.0613
Brugia malayi conserved hypotetical protein 0.0045 0.0394 0.0891
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0202 0.042
Schistosoma mansoni amine GPCR 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0122 0.016
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0051 0.0062
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0096 0.1037 0.1657
Brugia malayi G protein-coupled receptor 0.0021 0.0085 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Onchocerca volvulus 0.0042 0.0345 0.0628
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0087 0.0918 0.2118
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0085 0.0098
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0051 0.0224
Echinococcus granulosus g protein coupled receptor 0.0021 0.0085 0.0098
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1324 0.4845
Giardia lamblia Beta tubulin 0.035 0.424 1
Loa Loa (eye worm) tubulin alpha 2 0.0179 0.2078 0.4708
Loa Loa (eye worm) tubulin alpha 2 0.0179 0.2078 0.4708
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0085 0.0191
Schistosoma mansoni hypothetical protein 0.0106 0.116 0.1858
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0394 0.0891
Brugia malayi hypothetical protein 0.0066 0.0647 0.1465
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0146 0.0288
Echinococcus granulosus tubulin gamma 1 chain 0.02 0.2349 0.3804
Schistosoma mansoni hypothetical protein 0.0021 0.0085 0.0098
Schistosoma mansoni hypothetical protein 0.0125 0.14 0.225
Plasmodium vivax tubulin alpha chain, putative 0.0266 0.3177 0.7477
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0096 0.1037 0.1015
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0122 0.0276
Brugia malayi MH1 domain containing protein 0.0024 0.0122 0.0276
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0085 0.0098
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0085 0.0098
Schistosoma mansoni tubulin subunit beta 0.035 0.424 0.6899
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0085 0.0098
Echinococcus granulosus epidermal growth factor receptor 0.0164 0.1896 0.3062
Echinococcus granulosus single minded 2 0.0036 0.0271 0.0403
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0158 0.0356
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0085 0.006
Brugia malayi beta-tubulin, identical 0.035 0.424 0.9607
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0413 0.1446
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0055 0.005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0051 0.0062
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0085 0.0098
Echinococcus granulosus tubulin alpha 1C chain 0.0266 0.3177 0.5159
Toxoplasma gondii exonuclease III APE 0.0019 0.0055 0.0072
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1173 0.4282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.018 0.0406
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0271 0.0403
Mycobacterium ulcerans hypothetical protein 0.002 0.0072 0.0409
Trypanosoma brucei tubulin gamma chain 0.02 0.2349 0.5514
Leishmania major cytochrome p450-like protein 0.0027 0.0161 0.0323
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0085 0.006
Leishmania major hypothetical protein, conserved 0.0036 0.0271 0.0584
Echinococcus multilocularis tumor protein p63 0.0336 0.4061 0.4047
Brugia malayi ecdysteroid receptor 0.0096 0.1037 0.2349
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Loa Loa (eye worm) tubulin alpha 2 0.0066 0.0647 0.1464
Loa Loa (eye worm) tubulin beta chain 0.0087 0.0918 0.2078
Loa Loa (eye worm) tubulin gamma chain 0.02 0.2349 0.5322
Loa Loa (eye worm) hypothetical protein 0.0081 0.0844 0.1913
Onchocerca volvulus 0.0036 0.0278 0.0473
Brugia malayi hypothetical protein 0.0106 0.116 0.2628
Echinococcus multilocularis dihydrofolate reductase 0.0044 0.0369 0.0345
Trypanosoma cruzi tubulin delta chain 0.0087 0.0918 0.2118
Loa Loa (eye worm) tubulin beta-4 chain 0.035 0.424 0.9607
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Plasmodium vivax tubulin alpha chain, putative 0.0266 0.3177 0.7477
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0194 0.2275 0.3683
Onchocerca volvulus 0.0066 0.0647 0.1324
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0408 0.0909
Trichomonas vaginalis tubulin, putative 0.0113 0.1251 0.2949
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.0584
Schistosoma mansoni lamin 0.0027 0.0158 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0309 0.0729
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0394 0.0891
Schistosoma mansoni biogenic amine receptor 0.0021 0.0085 0.0098
Brugia malayi 6-phosphofructokinase 0.0108 0.1184 0.2681
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0461 0.1034
Brugia malayi nuclear receptor RXR 0.0045 0.0394 0.0891
Brugia malayi hypothetical protein 0.0051 0.0462 0.1047
Loa Loa (eye worm) DR-78 0.0045 0.0394 0.0891
Echinococcus multilocularis tubulin alpha chain 0.0266 0.3177 0.316
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0096 0.1037 0.2349
Onchocerca volvulus 0.0045 0.0394 0.0741
Schistosoma mansoni thyroid hormone receptor 0.0222 0.2618 0.4244
Loa Loa (eye worm) dihydrofolate reductase 0.0044 0.0369 0.0835
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1324 0.4845
Schistosoma mansoni alpha tubulin 0.0266 0.3177 0.5159
Echinococcus granulosus tubulin delta chain 0.0087 0.0918 0.1461
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.1037 0.1657
Schistosoma mansoni cpg binding protein 0.003 0.02 0.0287
Loa Loa (eye worm) steroid hormone receptor 0.0096 0.1037 0.2349
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0085 0.0191
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0135 0.0263
Onchocerca volvulus 0.0021 0.0085 0.0029
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0394 0.0741
Echinococcus multilocularis Tubulin alpha 1 chain 0.0266 0.3177 0.316
Entamoeba histolytica tubulin alpha-1 chain 0.0266 0.3177 0.7459
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0025 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Trypanosoma cruzi epsilon tubulin, putative 0.02 0.2349 0.5514
Brugia malayi Tubulin alpha-2 chain 0.0266 0.3177 0.7198
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0051 0.0097
Mycobacterium tuberculosis Probable reductase 0.0107 0.1173 0.4282
Loa Loa (eye worm) hypothetical protein 0.0153 0.1745 0.3954
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.031 0.0608
Trypanosoma brucei beta tubulin 0.035 0.424 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0051 0.0224
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Schistosoma mansoni tyrosine kinase 0.0163 0.1874 0.3026
Chlamydia trachomatis endonuclease IV 0.0076 0.0781 1
Brugia malayi isocitrate dehydrogenase 0.0047 0.0408 0.0923
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0271 0.0918
Schistosoma mansoni neuropeptide receptor 0.0021 0.0085 0.0098
Brugia malayi intermediate filament protein 0.0027 0.0158 0.0356
Brugia malayi putative neuropeptide receptor 0.0021 0.0085 0.0191
Trypanosoma cruzi beta tubulin, putative 0.035 0.424 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0085 0.0191
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0873 0.0851
Leishmania major beta tubulin 0.035 0.424 1
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1184 0.2697
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.2707 1
Loa Loa (eye worm) tubulin alpha chain 0.0266 0.3177 0.7198
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Schistosoma mansoni tubulin subunit gamma 0.02 0.2349 0.3804
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0051 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Schistosoma mansoni tyrosine kinase 0.0098 0.1054 0.1684
Toxoplasma gondii beta-1 tubulin, putative 0.035 0.424 1
Echinococcus granulosus tubulin alpha 0.02 0.2349 0.3804
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0085 0.006
Entamoeba histolytica tubulin family protein 0.035 0.424 1
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0161 0.0323
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0408 0.0909
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0055 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0271 0.0584
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0413 0.0934
Brugia malayi Muscleblind-like protein 0.0148 0.1694 0.3839
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0107 0.1168 0.2645
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0158 0.0356
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.0584
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0051 0.0062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0393 0.0369
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0394 0.037
Echinococcus multilocularis CREB binding protein 0.0073 0.0736 0.0713
Echinococcus multilocularis peroxisome assembly protein 26 0.0266 0.3177 0.316
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0085 0.006
Schistosoma mansoni tyrosine kinase 0.0164 0.1896 0.3062
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0347 0.0632
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0096 0.1037 0.1657
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1184 0.2792
Onchocerca volvulus Protein ultraspiracle homolog 0.0096 0.1037 0.2223
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0122 0.016
Brugia malayi Cytochrome P450 family protein 0.0056 0.053 0.12
Toxoplasma gondii endonuclease IV APN 0.0076 0.0781 0.1795
Echinococcus multilocularis FTZ F1 alpha 0.0096 0.1037 0.1015
Brugia malayi tubulin alpha-2 chain 0.0266 0.3177 0.7198
Schistosoma mansoni tubulin subunit alpha 0.0266 0.3177 0.5159
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0085 0.006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0408 0.0909
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.031 0.0676
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0051 0.0224
Brugia malayi Dopamine receptor 0.0021 0.0085 0.0191
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0051 0.0224
Schistosoma mansoni myosin xvIII 0.0021 0.0085 0.0098
Mycobacterium ulcerans epimerase 0.002 0.0072 0.0409
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.14 0.1378
Brugia malayi Dopamine receptor protein 1 0.0021 0.0085 0.0191
Echinococcus granulosus Tubulin alpha 1 chain 0.0266 0.3177 0.5159
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0085 0.0098
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0271 0.0918
Plasmodium vivax SET domain protein, putative 0.003 0.0202 0.042
Schistosoma mansoni single-minded 0.0048 0.043 0.0663
Onchocerca volvulus 0.0036 0.0271 0.0458
Mycobacterium leprae cell division protein FtsZ 0.0087 0.0918 0.6806
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0122 0.0098
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Plasmodium falciparum glutathione reductase 0.0047 0.0413 0.092
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0085 0.006
Echinococcus granulosus beta tubulin 0.035 0.424 0.6899
Schistosoma mansoni nuclear hormone receptor 0.0096 0.1037 0.1657
Schistosoma mansoni thyroid hormone receptor 0.0222 0.2618 0.4244
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.4269 0.9672
Leishmania major beta tubulin 0.035 0.424 1
Plasmodium vivax tubulin beta chain, putative 0.035 0.424 1
Loa Loa (eye worm) tubulin beta chain 0.035 0.424 0.9607
Brugia malayi MH2 domain containing protein 0.0024 0.0122 0.0276
Echinococcus multilocularis tubulin subunit TubB 0.0266 0.3177 0.316
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0135 0.0263
Trypanosoma cruzi epsilon tubulin, putative 0.02 0.2349 0.5514
Echinococcus multilocularis epidermal growth factor receptor 0.0164 0.1896 0.1875
Schistosoma mansoni neuropeptide receptor 0.0021 0.0085 0.0098
Echinococcus granulosus g protein coupled receptor 0.0021 0.0085 0.0098
Giardia lamblia Alpha-tubulin 0.0266 0.3177 0.7477
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0085 0.006
Echinococcus granulosus fmrfamide receptor 0.0021 0.0085 0.0098
Brugia malayi hypothetical protein 0.0045 0.0394 0.0891
Leishmania major beta tubulin 0.035 0.424 1
Brugia malayi Pre-SET motif family protein 0.0208 0.244 0.5528
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0202 0.029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0027 0.0158 0.0356
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0085 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Brugia malayi RE15519p 0.0021 0.0085 0.0191
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0055 0.0072
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0085 0.0098
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0202 0.0177
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0085 0.0098
Echinococcus granulosus Smad4 0.0024 0.0122 0.016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0309 0.07
Schistosoma mansoni adenoreceptor 0.0021 0.0085 0.0098
Brugia malayi larval opioid receptor 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0461 0.1626
Brugia malayi GnHR receptor homolog 0.0021 0.0085 0.0191
Brugia malayi 6-phosphofructokinase 0.0108 0.1184 0.2681
Onchocerca volvulus 0.0113 0.1251 0.2715
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0135 0.0263
Trichomonas vaginalis tubulin alpha chain, putative 0.0113 0.1251 0.2949
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0393 0.0369
Brugia malayi Melatonin receptor type 1A 0.0021 0.0085 0.0191
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0107 0.1168 0.1871
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0085 0.0191
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.116 0.1138
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Loa Loa (eye worm) hypothetical protein 0.0162 0.1868 0.4232
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0051 0.0062
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0394 0.0891
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.015 0.1718 0.4017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0271 0.0918
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0085 0.0098
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1184 0.2697
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0394 0.0604
Schistosoma mansoni chromobox protein 0.0069 0.0694 0.1095
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0085 0.006
Leishmania major beta tubulin 0.035 0.424 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0151 0.0342
Echinococcus multilocularis Tubulin beta 2C chain 0.035 0.424 0.4226
Echinococcus granulosus cpg binding protein 0.003 0.02 0.0287
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0085 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0085 0.0191
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0188 0.0387
Leishmania major beta tubulin 0.035 0.424 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0085 0.006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0462 0.0439
Echinococcus multilocularis ecdysone induced protein 78C 0.0096 0.1037 0.1015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0394 0.037
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi Flap endonuclease-1 0.0026 0.0146 0.033
Echinococcus granulosus Tubulin alpha 1 chain 0.0266 0.3177 0.5159
Onchocerca volvulus 0.003 0.0203 0.0302
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0462 0.1047
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.1184 0.1162
Entamoeba histolytica tubulin family protein 0.035 0.424 1
Onchocerca volvulus TPPP family protein homolog 0.0364 0.4414 1
Onchocerca volvulus 0.0036 0.0271 0.0458
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0051 0.0224
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0394 0.0604
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0413 0.0635
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0044 0.0369 0.1284
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0085 0.0098
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0188 0.0387
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0085 0.006
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0085 0.006
Brugia malayi Cytochrome P450 family protein 0.0027 0.0161 0.0363
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0153 0.1745 0.4116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0266 0.3177 0.7492
Brugia malayi beta-lactamase family protein 0.0036 0.0271 0.0613
Chlamydia trachomatis dihydrofolate reductase 0.0044 0.0369 0.4552
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0393 0.089
Leishmania major beta tubulin 0.035 0.424 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0087 0.0918 0.2164
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0051 0.0097
Brugia malayi hypothetical protein 0.0051 0.0462 0.1047
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0098 0.1054 0.1032
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0179 0.2078 0.4708
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0376 0.0834
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0085 0.006
Brugia malayi dihydrofolate reductase family protein 0.0044 0.0369 0.0835
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0085 0.006
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0104 0.1136 0.1819
Schistosoma mansoni ap endonuclease 0.0019 0.0055 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Toxoplasma gondii thioredoxin reductase 0.0047 0.0413 0.092
Schistosoma mansoni tubulin subunit epsilon 0.02 0.2349 0.3804
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1324 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0072 0.0177
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0394 0.037
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0146 0.0344
Echinococcus granulosus flap endonuclease 1 0.0026 0.0146 0.0198
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0085 0.006
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0085 0.006
Schistosoma mansoni hypothetical protein 0.0021 0.0085 0.0098
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Leishmania major delta tubulin, putative 0.0087 0.0918 0.2118
Schistosoma mansoni hypothetical protein 0.05 0.6135 1
Trypanosoma cruzi tubulin gamma chain 0.02 0.2349 0.5514
Onchocerca volvulus 0.0096 0.1037 0.2223
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.1661 0.2678
Mycobacterium ulcerans beta-lactamase 0.0036 0.0271 0.2125
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0085 0.0029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0085 0.0098
Echinococcus granulosus tubulin subunit TubB 0.0266 0.3177 0.5159
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0408 0.0384
Schistosoma mansoni alpha tubulin 0.0266 0.3177 0.5159
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0085 0.006
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0044 0.0369 0.25
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0051 0.0224
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0055 0.0262
Echinococcus granulosus FTZ F1 alpha 0.0096 0.1037 0.1657
Onchocerca volvulus 0.0021 0.0085 0.0029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1173 0.8813
Schistosoma mansoni biogenic amine receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0146 0.033
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.053 0.12
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0107 0.1168 0.2645
Onchocerca volvulus 0.0021 0.0085 0.0029
Schistosoma mansoni histamine h1 receptor 0.0021 0.0085 0.0098
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0055 0.0124
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0408 0.0384
Onchocerca volvulus 0.0021 0.0085 0.0029
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Echinococcus granulosus Tubulin beta 2C chain 0.035 0.424 0.6899
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0085 0.0191
Schistosoma mansoni biogenic amine receptor 0.0021 0.0085 0.0098
Giardia lamblia Delta tubulin 0.0087 0.0918 0.2118
Brugia malayi hypothetical protein 0.0162 0.1868 0.4232
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0122 0.016
Echinococcus granulosus Tubulin beta 2C chain 0.035 0.424 0.6899
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.1184 0.1897
Schistosoma mansoni tubulin subunit delta 0.0087 0.0918 0.1461
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0146 0.0288
Echinococcus multilocularis serotonin receptor 0.0021 0.0085 0.006
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0271 0.0584
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.018 0.0254
Echinococcus multilocularis smad 0.0024 0.0122 0.0098
Echinococcus multilocularis epidermal growth factor receptor 0.0306 0.3684 0.3668
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0598 0.0938
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0096 0.1037 0.1015
Echinococcus granulosus lamin 0.0027 0.0158 0.0217
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0143 0.1631 0.1611
Leishmania major beta tubulin 0.035 0.424 1
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1184 0.2792
Leishmania major epsilon tubulin, putative 0.02 0.2349 0.5514
Schistosoma mansoni neuropeptide receptor 0.0021 0.0085 0.0098
Leishmania major beta tubulin 0.035 0.424 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0085 0.006
Echinococcus granulosus peroxisome assembly protein 26 0.0266 0.3177 0.5159
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0096 0.1037 0.2349
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0146 0.0288
Echinococcus multilocularis neuropeptide receptor A26 0.0478 0.5861 0.585
Echinococcus multilocularis tubulin subunit beta 0.035 0.424 0.4226
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0188 0.0387
Onchocerca volvulus 0.0027 0.0158 0.0197
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus multilocularis insulin receptor 0.0098 0.1054 0.1032
Loa Loa (eye worm) tubulin alpha chain 0.0266 0.3177 0.7198
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0085 0.006
Schistosoma mansoni amine GPCR 0.0021 0.0085 0.0098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.1037 0.1015
Echinococcus granulosus neuropeptide receptor A26 0.0478 0.5861 0.9551
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Schistosoma mansoni smad1 5 8 and 0.0024 0.0122 0.016
Echinococcus granulosus neuropeptide s receptor 0.0478 0.5861 0.9551
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0122 0.0276
Echinococcus multilocularis tubulin alpha chain 0.0266 0.3177 0.316
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1184 0.2697
Trypanosoma brucei tubulin delta chain 0.0087 0.0918 0.2118
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0271 0.0639
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0055 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0166 0.0392
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Brugia malayi Furin-like cysteine rich region family protein 0.0306 0.3684 0.8346
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0146 0.0288
Trichomonas vaginalis tubulin epsilon chain, putative 0.035 0.424 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0051 0.0224
Echinococcus multilocularis tubulin alpha chain 0.0266 0.3177 0.316
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Schistosoma mansoni hypothetical protein 0.05 0.6135 1
Echinococcus multilocularis lamin 0.0027 0.0158 0.0133
Brugia malayi steroid hormone receptor 0.0096 0.1037 0.2349
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0085 0.0098
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0085 0.0191
Echinococcus granulosus insulin receptor 0.0098 0.1054 0.1684
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0006 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0055 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0202 0.029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0376 0.0888
Brugia malayi TAZ zinc finger family protein 0.0104 0.1136 0.2574
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Echinococcus multilocularis thymidylate synthase 0.0107 0.1168 0.1146
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0085 0.0098
Entamoeba histolytica tubulin gamma chain 0.02 0.2349 0.5482
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0051 0.0062
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1184 0.2749
Brugia malayi MH2 domain containing protein 0.0352 0.4269 0.9672
Loa Loa (eye worm) tubulin alpha-2 chain 0.0266 0.3177 0.7198
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0085 0.006
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0096 0.1037 0.1657
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Leishmania major beta tubulin 0.035 0.424 1
Brugia malayi Dihydrofolate reductase 0.0044 0.0369 0.0835
Brugia malayi cytochrome P450 0.0018 0.0051 0.0114
Mycobacterium tuberculosis Cell division protein FtsZ 0.0087 0.0918 0.3329
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0085 0.0098
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.116 0.1858
Schistosoma mansoni amine GPCR 0.0021 0.0085 0.0098
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0085 0.0098
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1184 0.1897
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0271 0.0918
Schistosoma mansoni retinoic acid receptor RXR 0.0194 0.2275 0.3683
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0006 0.0014
Trypanosoma brucei epsilon tubulin 0.02 0.2349 0.5514
Echinococcus granulosus neuropeptide receptor 0.0021 0.0085 0.0098
Schistosoma mansoni tyrosine kinase 0.0098 0.1054 0.1684
Trichomonas vaginalis tubulin alpha chain, putative 0.0113 0.1251 0.2949
Toxoplasma gondii alpha-tubulin I, putative 0.0266 0.3177 0.7477
Onchocerca volvulus 0.0049 0.044 0.0847
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0085 0.0191
Trypanosoma cruzi alpha tubulin, putative 0.0266 0.3177 0.7477
Brugia malayi nuclear receptor NHR-67 0.0045 0.0394 0.0891
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0394 0.0891
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0051 0.0224
Schistosoma mansoni tubulin subunit beta 0.0087 0.0918 0.1461
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0051 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.0096 0.1037 0.1657
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0085 0.0098
Echinococcus multilocularis serotonin receptor 0.0021 0.0085 0.006
Echinococcus granulosus dihydrofolate reductase 0.0044 0.0369 0.0564
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0051 0.0097
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0408 0.1428
Loa Loa (eye worm) hypothetical protein 0.0076 0.0781 0.177
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0394 0.0604
Brugia malayi MH2 domain containing protein 0.0024 0.0122 0.0276
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0085 0.006
Schistosoma mansoni tubulin subunit alpha 0.0087 0.0918 0.1461
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0271 0.2125
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0146 0.0288
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Brugia malayi Tubulin beta-1 chain 0.035 0.424 0.9607
Brugia malayi Dopamine receptor protein 2 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0051 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0085 0.006
Trypanosoma brucei alpha tubulin, putative 0.0113 0.1251 0.2908
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0085 0.0191
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0394 0.0604
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.1661 0.3763
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0164 0.1896 0.3062
Schistosoma mansoni ap endonuclease 0.0019 0.0055 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1047
Plasmodium vivax delta tubulin, putative 0.0087 0.0918 0.2118
Trichomonas vaginalis tubulin alpha chain, putative 0.0113 0.1251 0.2949
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0096 0.1037 0.2349
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Trichomonas vaginalis tubulin, putative 0.0087 0.0918 0.2164
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0055 0.0262
Echinococcus multilocularis tubulin alpha chain 0.0266 0.3177 0.316
Brugia malayi G-protein coupled receptor 0.0021 0.0085 0.0191
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0166 0.0392
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0051 0.0224
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Echinococcus multilocularis tubulin beta 1 chain 0.035 0.424 0.4226
Loa Loa (eye worm) hypothetical protein 0.003 0.0202 0.0456
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0271 0.0613
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0096 0.1037 0.2349
Leishmania major trypanothione reductase 0.0047 0.0413 0.092
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0051 0.0224
Leishmania major cytochrome p450-like protein 0.0018 0.0051 0.0062
Brugia malayi tubulin alpha chain - mouse 0.0266 0.3177 0.7198
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0051 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.1037 0.2349
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0394 0.0604
Echinococcus granulosus tubulin alpha chain 0.0266 0.3177 0.5159
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0085 0.0098
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0096 0.1037 0.1657
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi Steroid receptor seven-up type 2 0.0096 0.1037 0.2349
Schistosoma mansoni CREB-binding protein 2 0.0104 0.1136 0.1819
Plasmodium falciparum tubulin delta chain, putative 0.0087 0.0918 0.2118
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0055 0.0072
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0188 0.2154
Echinococcus multilocularis tubulin gamma 1 chain 0.02 0.2349 0.233
Brugia malayi nuclear hormone receptor 0.0096 0.1037 0.2349
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0051 0.0097
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1184 0.2792
Trypanosoma brucei alpha tubulin 0.0266 0.3177 0.7477
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0096 0.1037 0.2349
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0072 0.0162
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Entamoeba histolytica hypothetical protein 0.0106 0.116 0.264
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0413 0.092
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0051 0.0224
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0096 0.1037 0.2349
Trichomonas vaginalis tubulin beta chain, putative 0.0266 0.3177 0.7492
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0087 0.0918 1
Trichomonas vaginalis tubulin, putative 0.035 0.424 1
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1184 0.2792
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0781 0.5737
Loa Loa (eye worm) hypothetical protein 0.0148 0.1694 0.3839
Loa Loa (eye worm) beta-tubulin 0.035 0.424 0.9607
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0408 0.0909
Brugia malayi hypothetical protein 0.0021 0.0085 0.0191
Schistosoma mansoni cpg binding protein 0.0029 0.018 0.0253
Loa Loa (eye worm) beta-lactamase 0.0036 0.0271 0.0613
Schistosoma mansoni smad 0.0024 0.0122 0.016
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0394 0.0891
Loa Loa (eye worm) acetyltransferase 0.0146 0.1661 0.3763
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0085 0.0098
Mycobacterium tuberculosis Conserved protein 0.0036 0.0271 0.0918
Plasmodium falciparum tubulin beta chain 0.035 0.424 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0271 0.0403
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0161 0.0363
Brugia malayi Pre-SET motif family protein 0.003 0.0202 0.0456
Echinococcus multilocularis Tubulin alpha 1 chain 0.0266 0.3177 0.316
Schistosoma mansoni amine GPCR 0.0021 0.0085 0.0098
Onchocerca volvulus 0.0107 0.1168 0.2524
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0188 0.0443
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0087 0.0918 0.2118
Mycobacterium ulcerans hypothetical protein 0.0036 0.0271 0.2125
Loa Loa (eye worm) BEN-1 protein 0.035 0.424 0.9607
Trichomonas vaginalis tubulin epsilon chain, putative 0.035 0.424 1
Echinococcus multilocularis chromobox protein 1 0.0069 0.0694 0.0671
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0408 0.0923
Echinococcus granulosus tubulin alpha chain 0.0266 0.3177 0.5159
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0096 0.1037 0.2349
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0146 0.0217
Brugia malayi Tubulin alpha chain 0.0266 0.3177 0.7198
Echinococcus multilocularis tubulin alpha 3 chain 0.0266 0.3177 0.316
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0408 0.0384
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0096 0.1037 0.1657
Leishmania major beta tubulin 0.035 0.424 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.1037 0.2349
Schistosoma mansoni flap endonuclease-1 0.0023 0.0115 0.0147
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.015 0.1718 0.4017
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0085 0.0098
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0462 0.1047
Entamoeba histolytica hypothetical protein 0.0106 0.116 0.264
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0394 0.0604
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1184 0.1897
Brugia malayi hypothetical protein 0.0016 0.0023 0.0052
Onchocerca volvulus 0.0236 0.2801 0.6285
Onchocerca volvulus 0.0021 0.0085 0.0029
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0085 0.0098
Brugia malayi Tubulin gamma chain 0.02 0.2349 0.5322
Schistosoma mansoni tyrosine kinase 0.0164 0.1896 0.3062
Onchocerca volvulus 0.0021 0.0085 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0694 0.1636
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0044 0.0103
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0271 0.0613
Trypanosoma brucei epsilon tubulin 0.02 0.2349 0.5514
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0085 0.0098
Trichomonas vaginalis tubulin alpha chain, putative 0.02 0.2349 0.554
Onchocerca volvulus Bile acid receptor homolog 0.0096 0.1037 0.2223
Brugia malayi thymidylate synthase 0.0107 0.1168 0.2646
Schistosoma mansoni intermediate filament proteins 0.0027 0.0158 0.0217
Onchocerca volvulus 0.0027 0.0158 0.0197
Trypanosoma brucei trypanothione reductase 0.0047 0.0413 0.092
Echinococcus granulosus serotonin receptor 0.0021 0.0085 0.0098
Trypanosoma brucei beta tubulin 0.035 0.424 1
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0408 0.0909
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0393 0.089
Loa Loa (eye worm) TK/INSR protein kinase 0.0098 0.1054 0.2387
Onchocerca volvulus 0.0021 0.0085 0.0029
Echinococcus granulosus smad 0.0024 0.0122 0.016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0394 0.0741
Plasmodium falciparum alpha tubulin 2 0.0266 0.3177 0.7477
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.031 0.0676
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0873 0.1389
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Leishmania major alpha tubulin 0.0266 0.3177 0.7477
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0085 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.0891
Brugia malayi Cytochrome P450 family protein 0.0027 0.0161 0.0363
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.1251 0.2949
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0051 0.0224
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0085 0.0098
Brugia malayi AKH receptor 0.0021 0.0085 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.1037 0.2349
Echinococcus granulosus Tubulin beta 2C chain 0.035 0.424 0.6899
Plasmodium falciparum thioredoxin reductase 0.0047 0.0413 0.092
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0461 0.1087
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0085 0.0098
Echinococcus multilocularis tubulin alpha 1C chain 0.0266 0.3177 0.316
Brugia malayi ecdysone receptor 0.0045 0.0394 0.0891
Echinococcus multilocularis transcription factor eb 0.0107 0.1174 0.1152
Onchocerca volvulus 0.0029 0.018 0.0248
Echinococcus granulosus tubulin beta 4A class IVa 0.035 0.424 0.6899
Brugia malayi hypoxia-induced factor 1 0.015 0.1709 0.3872
Onchocerca volvulus 0.0036 0.0271 0.0458
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0179 0.2078 0.4708
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0271 0.0918
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0085 0.0098
Leishmania major gamma-tubulin 0.02 0.2349 0.5514
Plasmodium falciparum alpha tubulin 1 0.0266 0.3177 0.7477
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0051 0.0224
Schistosoma mansoni alpha tubulin 0.0266 0.3177 0.5159
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0376 0.0834
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0188 0.0443
Brugia malayi chromobox protein homolog 3 0.0039 0.0309 0.07
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0085 0.0098
Schistosoma mansoni coup transcription factor 0.0096 0.1037 0.1657
Echinococcus multilocularis CREB binding protein 0.0017 0.0028 0.0003
Loa Loa (eye worm) p25-alpha family protein 0.0364 0.4414 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Brugia malayi Protein kinase domain containing protein 0.0098 0.1054 0.2387
Leishmania major beta tubulin 0.035 0.424 1
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0271 0.0247
Echinococcus multilocularis Tubulin beta 2C chain 0.035 0.424 0.4226
Loa Loa (eye worm) hypothetical protein 0.0021 0.0085 0.0191
Leishmania major beta tubulin 0.035 0.424 1
Echinococcus granulosus sex peptide receptor 0.0021 0.0085 0.0098
Echinococcus multilocularis sex peptide receptor 0.0021 0.0085 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0085 0.0098
Echinococcus granulosus jun protein 0.0083 0.0873 0.1389
Echinococcus multilocularis geminin 0.05 0.6135 0.6125
Leishmania major zeta tubulin, putative 0.0087 0.0918 0.2118
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0051 0.0062
Echinococcus multilocularis thyroid hormone receptor alpha 0.0222 0.2618 0.2599
Brugia malayi sulfakinin receptor protein 0.0021 0.0085 0.0191
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0376 0.0834
Brugia malayi Tubulin beta chain 0.0113 0.1251 0.2833
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0085 0.0098
Schistosoma mansoni smad1 5 8 and 0.0024 0.0122 0.016
Mycobacterium ulcerans lipase LipD 0.0036 0.0271 0.2125

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 34.8 % Inhibition of aromatase in denucleated ovarian fraction extracted from PMSG pretreated Wistar rat by using testosterone as substrate at 1 uM ChEMBL. 26469743

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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