Detailed information for compound 234634

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.976 | Formula: C24H32ClN2O2-
  • H donors: 1 H acceptors: 2 LogP: 3.61 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)[C@@H]1CCCN(C1)CCCCCCN(c1ccccc1)c1ccccc1.[Cl-]
  • InChi: 1S/C24H32N2O2.ClH/c27-24(28)21-12-11-18-25(20-21)17-9-1-2-10-19-26(22-13-5-3-6-14-22)23-15-7-4-8-16-23;/h3-8,13-16,21H,1-2,9-12,17-20H2,(H,27,28);1H/p-1/t21-;/m1./s1
  • InChiKey: FUESIYSAMXENEI-ZMBIFBSDSA-M  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0019 0.0044 0.026
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0001 0.0009
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0045 0.0204
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.1445
Giardia lamblia DINP protein human, muc B family 0.0019 0.0046 0.0443
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.1445
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0045 0.0045
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.001 0.0013 0.0013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0049 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0014 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0044 0.1191
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0036 0.0075
Brugia malayi hypothetical protein 0.0019 0.0045 0.03
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0049 0.0049
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0045 0.0045
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.004 0.008
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.004 0.0083
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0093 0.0626
Onchocerca volvulus 0.0023 0.0062 0.0364
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Schistosoma mansoni nuclear receptor 0.0009 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0094
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0007 0.0001 0.0002
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0141 0.2896
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0007 0.0001 0.0002
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0007 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0069 0.023 0.1546
Schistosoma mansoni ap endonuclease 0.0019 0.0044 0.0044
Brugia malayi Flap endonuclease-1 0.0027 0.0075 0.0502
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0062 0.0124
Plasmodium falciparum thioredoxin reductase 0.0048 0.0154 0.3177
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0082 0.2012
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.049 0.0982
Schistosoma mansoni hypothetical protein 0.0069 0.023 0.023
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0165 0.0586 0.3937
Plasmodium falciparum glutathione reductase 0.0017 0.0037 0.0757
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0428 0.0428
Brugia malayi 6-phosphofructokinase 0.0107 0.0371 0.2491
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0049 0.0049
Schistosoma mansoni loxhd1 0.0137 0.0484 0.0484
Onchocerca volvulus 0.005 0.016 0.0945
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.103 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0029 0.0029
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0165 0.0586 0.0586
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0001 0.0001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0021 0.0139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.001 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0251 0.0251
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0141 0.3289
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0037 0.0632
Toxoplasma gondii hypothetical protein 0.0026 0.0073 0.1244
Brugia malayi hypothetical protein 0.005 0.016 0.1077
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0049 0.0049
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0428 0.0428
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0049 0.0049
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.1003
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0198 0.0198
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0048 0.032
Brugia malayi Sex muscle abnormal protein 5 0.0007 0.0002 0.0014
Loa Loa (eye worm) DR-78 0.0009 0.001 0.0066
Schistosoma mansoni growth factor receptor-bound protein 0.0007 0.0002 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.0001 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0371 0.1691
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0154 0.4162
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0044 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.001 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.001 0.001
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0415
Schistosoma mansoni rab6-interacting 0.0137 0.0484 0.0484
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0082 0.1683
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0415
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0093 0.0626
Trypanosoma brucei unspecified product 0.0013 0.0024 0.0641
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0007 0.0001 0.0002
Schistosoma mansoni cpg binding protein 0.0091 0.0313 0.0313
Trichomonas vaginalis helicase, putative 0.0019 0.0047 0.0216
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Onchocerca volvulus 0.0086 0.0294 0.1736
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Mycobacterium leprae putative cytochrome p450 0.0007 0.0001 0.0002
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.026 0.026
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.049 0.1016
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0338 0.0338
Schistosoma mansoni cpg binding protein 0.0086 0.0294 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0251 0.6769
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0082 0.0082
Echinococcus multilocularis GPCR, family 2 0.0032 0.0093 0.0093
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.004 0.0813
Onchocerca volvulus 0.005 0.016 0.0945
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0001 0.0001
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 0.052
Echinococcus multilocularis glycoprotein Antigen 5 0.005 0.016 0.016
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.004 0.0813
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0007 0.0001 0.0002
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0001 0.0009
Schistosoma mansoni tyrosine kinase 0.001 0.0013 0.0013
Onchocerca volvulus 0.0009 0.0008 0.0049
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0007 0.0001 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0203 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.084 0.084
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0075 0.2015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0062 0.0124
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0251 0.1145
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0371 0.2491
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0007 0.0001 0.0002
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0037 0.017
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0007 0.0001 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0049 0.0327
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.0001 0.0002
Leishmania major DNA polymerase eta, putative 0.0044 0.0139 0.3246
Brugia malayi Nuclear hormone receptor E75 0.0009 0.001 0.0066
Schistosoma mansoni tyrosine kinase 0.0275 0.0995 0.0995
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0044 0.0201
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0044 0.0044
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0597 0.2192 1
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0137 0.0484 0.3255
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Schistosoma mansoni microtubule-associated protein tau 0.2701 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0039
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Schistosoma mansoni tyrosine kinase 0.0086 0.0296 0.0296
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0037 0.0757
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0021 0.0139
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0001 0.0001
Brugia malayi Furin-like cysteine rich region family protein 0.0275 0.0995 0.6683
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0044 0.1191
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0154 0.0154
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0428 0.0428
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0049 0.0049
Brugia malayi Pre-SET motif family protein 0.006 0.0198 0.1331
Schistosoma mansoni thyroid hormone receptor 0.002 0.0049 0.0049
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.007 0.0472
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0044 0.0297
Onchocerca volvulus 0.0011 0.0014 0.0085
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0046 0.0095
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0062 0.0062
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0007 0.0002 0.0014
Echinococcus multilocularis NCK adaptor protein 0.0007 0.0002 0.0002
Echinococcus multilocularis transmembrane protease serine 3 0.005 0.016 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0049 0.0327
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0045 0.0045
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0348 0.2339
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0154 0.032
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0049 0.0156 0.0712
Toxoplasma gondii hypothetical protein 0.0019 0.0044 0.075
Schistosoma mansoni tyrosine kinase 0.0201 0.072 0.072
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.087
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0045 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0001 0.0001
Schistosoma mansoni nuclear receptor 0.0009 0.001 0.001
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0338 0.1542
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.0431 0.0431
Brugia malayi ecdysteroid receptor 0.002 0.0049 0.0327
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0039
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0037 0.087
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0156 0.071
Echinococcus multilocularis Polycystic kidney disease protein 0.0137 0.0484 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0251 0.1145
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0046 0.0046
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0062 0.0282
Leishmania major DNA polymerase kappa, putative 0.0019 0.0046 0.1068
Schistosoma mansoni hypothetical protein 0.0035 0.0107 0.0107
Brugia malayi Trypsin-like protease protein 5 0.005 0.016 0.1077
Plasmodium vivax SET domain protein, putative 0.006 0.0198 0.4083
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0049 0.0049
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0037 0.1003
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0062 0.0282
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0204
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0049 0.0327
Plasmodium vivax multidomain scavenger receptor, putative 0.0137 0.0484 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.005 0.016 0.016
Brugia malayi 6-phosphofructokinase 0.0107 0.0371 0.2491
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0037
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0082 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0036 0.0075
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0094
Echinococcus multilocularis microtubule associated protein 2 0.2701 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0799 0.294 0.294
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.002 0.0089
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 0.5355
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.026 0.4416
Onchocerca volvulus 0.0019 0.0044 0.026
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0268
Entamoeba histolytica hypothetical protein 0.0035 0.0107 0.0486
Brugia malayi Protein kinase domain containing protein 0.0165 0.0586 0.3937
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0049 0.0327
Echinococcus granulosus muscleblind protein 0.0301 0.1093 0.1093
Brugia malayi nuclear receptor RXR 0.0009 0.001 0.0066
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0001
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0001 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0428 0.0428
Echinococcus multilocularis insulin receptor 0.0086 0.0296 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0036 0.0075
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0037 0.017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0142 0.0142
Brugia malayi nuclear receptor NHR-67 0.0009 0.001 0.0066
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0007 0.0001 0.0002
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0045 0.0045
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0198 0.0198
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.002 0.0089
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0082 0.1683
Brugia malayi conserved hypotetical protein 0.0009 0.001 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0049 0.0049
Trypanosoma brucei unspecified product 0.0019 0.0046 0.1232
Echinococcus multilocularis cpg binding protein 0.0091 0.0313 0.0313
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0384 0.0795
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0428 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0142 0.0142
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0142 0.0951
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0075 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0156 0.071
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 0.052
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0338 0.0338
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.0044 0.0044
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.049 0.0982
Echinococcus granulosus cpg binding protein 0.0091 0.0313 0.0313
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0007 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0203 0.0203
Onchocerca volvulus 0.002 0.0049 0.0287
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0007 0.0001 0.0002
Schistosoma mansoni tsg101-related 0.0049 0.0156 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0048 0.0048
Onchocerca volvulus 0.005 0.016 0.0945
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.066 0.066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus multilocularis 0.0166 0.0593 0.0593
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0251 0.0251
Schistosoma mansoni cpg binding protein 0.0091 0.0313 0.0313
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0251 0.6769
Brugia malayi Nuclear hormone receptor E75 0.0009 0.001 0.0066
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0007 0.0001 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Schistosoma mansoni tyrosine kinase 0.0201 0.072 0.072
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0075 0.1532
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0046 0.0046
Echinococcus granulosus Polycystic kidney disease protein 0.0137 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Plasmodium falciparum glutathione reductase 0.0048 0.0154 0.3177
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0046 0.0208
Loa Loa (eye worm) hypothetical protein 0.0301 0.1093 0.7342
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0082 0.1394
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0009 0.001 0.001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0082 0.2012
Entamoeba histolytica hypothetical protein 0.0012 0.002 0.0089
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Loa Loa (eye worm) hypothetical protein 0.0137 0.0484 0.3255
Schistosoma mansoni hypothetical protein 0.1226 0.4524 0.4524
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0044 0.0201
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1307 0.4827 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.009 0.2432
Echinococcus granulosus tyrosine protein kinase Btk29A 0.001 0.0013 0.0013
Loa Loa (eye worm) nuclear receptor NHR-67 0.0009 0.001 0.0066
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0044 0.0296
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.001 0.001
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0037 0.1432
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0082 0.1683
Brugia malayi hypothetical protein 0.0009 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0049 0.0327
Onchocerca volvulus 0.0009 0.001 0.0058
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0251 0.0251
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0001 0.0006
Trypanosoma brucei unspecified product 0.0013 0.0024 0.0641
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0004
Brugia malayi RNA binding protein 0.0061 0.0203 0.1365
Toxoplasma gondii hypothetical protein 0.0019 0.0044 0.075
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0037 0.025
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.3795
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0014 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0203 0.0203
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0047 0.0216
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0075 0.0725
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0415
Onchocerca volvulus 0.0019 0.0044 0.026
Schistosoma mansoni flap endonuclease-1 0.0024 0.0065 0.0065
Schistosoma mansoni zinc finger protein 0.0009 0.001 0.001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0009 0.001 0.001
Leishmania major cytochrome p450-like protein 0.0007 0.0001 0.002
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0251 0.0251
Onchocerca volvulus 0.0464 0.1696 1
Brugia malayi hypothetical protein 0.0137 0.0484 0.3255
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0044 0.0091
Onchocerca volvulus 0.005 0.016 0.0945
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.026 0.4416
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.001 0.0013 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus granulosus growth factor receptor bound protein 2 0.0007 0.0002 0.0002
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.001 0.0013 0.0013
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0045 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0062 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0251 0.1145
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0001 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0046 0.0307
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0044 0.0901
Schistosoma mansoni kinase 0.005 0.016 0.016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0062 0.0124
Loa Loa (eye worm) hypothetical protein 0.0123 0.0431 0.2894
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0429 0.089
Echinococcus granulosus GPCR family 2 0.0032 0.0093 0.0093
Echinococcus granulosus glycoprotein Antigen 5 0.005 0.016 0.016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0062 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0082 0.1394
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0198 0.0198
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.026 0.052
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0268
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0162 0.0162
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Schistosoma mansoni nck2/grb4 0.0007 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0049 0.0327
Trypanosoma brucei cytochrome P450, putative 0.0007 0.0001 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Echinococcus multilocularis muscleblind protein 0.0301 0.1093 0.1093
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0082 0.0796
Brugia malayi nuclear hormone receptor 0.002 0.0049 0.0327
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0429 0.089
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0046 0.0091
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0093 0.0626
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0044 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0198 0.0198
Plasmodium falciparum thioredoxin reductase 0.0017 0.0037 0.0757
Schistosoma mansoni tsg101-related 0.006 0.0197 0.0197
Echinococcus multilocularis RUN 0.0137 0.0484 0.0484
Echinococcus multilocularis tyrosine protein kinase Fgr 0.001 0.0013 0.0013
Brugia malayi tailless protein 0.0009 0.001 0.0066
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0044 0.0429
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0046 0.0091
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1352 0.4993 1
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Schistosoma mansoni nuclear hormone receptor 0.002 0.0049 0.0049
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0139 0.3745
Loa Loa (eye worm) TK/EGFR protein kinase 0.0275 0.0995 0.6683
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0045 0.03
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0046 0.0046
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Echinococcus granulosus flap endonuclease 1 0.0027 0.0075 0.0075
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.084 0.084
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0007 0.0001 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0049 0.0327
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0002 0.0014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0049 0.0049
Brugia malayi hypothetical protein 0.0009 0.001 0.0066
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0123 0.0431 0.0431
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0072 0.0241 0.0241
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0001 0.0001
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0165 0.0586 0.3454
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Entamoeba histolytica hypothetical protein 0.0012 0.002 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0002 0.0014
Echinococcus granulosus tyrosine protein kinase Src42A 0.001 0.0013 0.0013
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0007 0.0001 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0049 0.0049
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0014 0.0014
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0049 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Echinococcus granulosus epidermal growth factor receptor 0.0275 0.0995 0.0995
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0001 0.0006
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0045 0.0141 0.0141
Echinococcus multilocularis nuclear receptor nhr 48 0.0009 0.001 0.001
Brugia malayi PXA domain containing protein 0.0019 0.0045 0.03
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0044 0.0044
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0155 0.055 0.055
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0198 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0338 0.9122
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0428 0.0886
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0072 0.0241 0.0241
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0044 0.0044
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0073 0.15
Schistosoma mansoni hypothetical protein 0.005 0.016 0.016
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0007 0.0001 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Echinococcus granulosus thyroid hormone receptor alpha 0.0009 0.001 0.001
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0251 0.0251
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0045 0.0141 0.0945
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0371 0.8668
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0141 0.0291
Echinococcus granulosus enteropeptidase 0.005 0.016 0.016
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0045 0.0045
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0037 0.1003
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.3795
Echinococcus multilocularis enteropeptidase 0.005 0.016 0.016
Echinococcus granulosus epidermal growth factor receptor 0.0204 0.0731 0.0731
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0007 0.0001 0.0002
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0049 0.0287
Schistosoma mansoni adapter molecule crk 0.0007 0.0002 0.0002
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.006 0.1623
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0141 0.0291
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0001 0.0003
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Loa Loa (eye worm) hypothetical protein 0.0233 0.084 0.5643
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0007 0.0001 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0139 0.0933
Trypanosoma brucei ISWI complex protein 0.0009 0.0009 0.0233
Brugia malayi Cytochrome P450 family protein 0.0007 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0137 0.0484 0.0484
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0037 0.0757
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0428 0.7272
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0007 0.0001 0.0002
Brugia malayi Trypsin family protein 0.005 0.016 0.1077
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0044 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0094
Brugia malayi hypothetical protein 0.0019 0.0045 0.03
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0045 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0049 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0046 0.1232
Echinococcus multilocularis muscleblind protein 1 0.0301 0.1093 0.1093
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0007 0.0001 0.0002
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 0.2522
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0001 0.0001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0045 0.03
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0045 0.0141 0.3795
Echinococcus granulosus Mastin 0.005 0.016 0.016
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0082 0.1394
Schistosoma mansoni coup transcription factor 0.002 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0203 0.0203
Loa Loa (eye worm) TK/INSR protein kinase 0.0086 0.0296 0.1988
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0086 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0077 0.026 0.1745
Leishmania major DNA polymerase eta, putative 0.0031 0.009 0.2108
Brugia malayi cytochrome P450 0.0007 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0035 0.0107 0.0486
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0007 0.0001 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Mycobacterium tuberculosis Probable reductase 0.011 0.0384 0.0795
Schistosoma mansoni ap endonuclease 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0044 0.0044
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0045 0.0141 0.0141
Onchocerca volvulus 0.0048 0.0151 0.0893
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0048
Brugia malayi Cytochrome P450 family protein 0.0007 0.0001 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0429 0.086
Schistosoma mansoni hypothetical protein 0.0032 0.0093 0.0093
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.075
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0023
Onchocerca volvulus 0.0019 0.0044 0.026
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0251 0.5868
Schistosoma mansoni hypothetical protein 0.0032 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.026 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0023
Echinococcus multilocularis tyrosine protein kinase Src42A 0.001 0.0013 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0049 0.0287
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.076 0.2796 0.2796
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0045 0.03
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0415
Echinococcus multilocularis expressed protein 0.0365 0.1329 0.1329
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0044 0.0044
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0.0001 0.0023
Trypanosoma brucei polo-like protein kinase 0.0098 0.0338 0.9122
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0371 0.0371
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0007 0.0001 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0142 0.0142
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0.0001 0.002
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0046 0.1232
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0049 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0009 0.001 0.001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0007 0.0001 0.0002
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0045 0.03
Schistosoma mansoni hypothetical protein 0.0032 0.0093 0.0093
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0073 0.15
Echinococcus granulosus dna polymerase eta 0.0044 0.0139 0.0139
Schistosoma mansoni protein kinase 0.0155 0.055 0.055
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.075
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0044 0.1032
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.026 0.5355
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0198 0.3369
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0037 0.1432
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0045 0.0045
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0046 0.0046
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0371 0.36
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0044 0.0088
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0165 0.0586 0.3937
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0049 0.0049
Plasmodium falciparum flap endonuclease 1 0.0027 0.0075 0.1532
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.001 0.0013 0.0013
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0049 0.0327
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0047 0.0047
Schistosoma mansoni tyrosine kinase 0.0204 0.0731 0.0731
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0007 0.0001 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0142 0.0951
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0009 0.0009 0.0039
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0049 0.0049
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0154 0.3177
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Brugia malayi Tyrosine-protein kinase abl-1 0.001 0.0013 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.002 0.0528
Treponema pallidum NADH oxidase 0.0017 0.0037 0.0361
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0165 0.0586 0.0586
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0268
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0107 0.0107
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0082 0.055
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Brugia malayi nuclear receptor RXR 0.001 0.0014 0.0094
Loa Loa (eye worm) solute carrier family 6 member 4 0.0019 0.0044 0.0296
Trichomonas vaginalis set domain proteins, putative 0.0464 0.1696 0.7738
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0007 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0007 0.0001 0.0002
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0082 0.0796
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0073 0.0147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Echinococcus multilocularis dna polymerase eta 0.0044 0.0139 0.0139
Brugia malayi Probable ClpP-like protease 0.0077 0.026 0.1745
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0141 0.2896
Loa Loa (eye worm) hypothetical protein 0.006 0.0198 0.1331
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0183 0.0183
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0037 0.0361
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0007 0.0002 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0045 0.0141 0.0141
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0045 0.0045
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0044 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0049 0.0327
Brugia malayi Cytochrome P450 family protein 0.0007 0.0001 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0074 0.0251 0.1686
Trypanosoma brucei trypanothione reductase 0.0048 0.0154 0.4162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0049 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0045
Trichomonas vaginalis hypothetical protein 0.0035 0.0105 0.0477
Loa Loa (eye worm) CYP4Cod1 0.0007 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0139 0.0933
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.001 0.001
Schistosoma mansoni tsg101-related 0.006 0.0197 0.0197
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0009 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Trichomonas vaginalis hypothetical protein 0.001 0.0014 0.0064
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0268
Brugia malayi ecdysone receptor 0.0009 0.001 0.0066
Leishmania major trypanothione reductase 0.0048 0.0154 0.3608
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0044 0.0044
Loa Loa (eye worm) norepinephrine transporter 0.0019 0.0044 0.0296
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0124
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.0001 0.0023
Loa Loa (eye worm) hypothetical protein 0.01 0.0348 0.2339
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0049 0.0327
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0045 0.03
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0597 0.2192 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0251 0.2437
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0001 0.0015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0046 0.1068
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0049 0.0049
Echinococcus granulosus serotonin transporter 0.0019 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.001 0.0013 0.0013
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0204 0.0731 0.0731
Onchocerca volvulus 0.0007 0.0001 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0007 0.0001 0.0002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0371 1
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0037 0.0632
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0024 0.0641
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0044 0.0044
Treponema pallidum sodium- and chloride- dependent transporter 0.0019 0.0044 0.0428
Echinococcus granulosus RUN 0.0137 0.0484 0.0484
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0428 0.0857
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0045 0.0045
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.004 0.012
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.026 0.026
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0348 0.2339
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0044 0.1191
Loa Loa (eye worm) doublecortin family protein 0.0137 0.0484 0.3255
Onchocerca volvulus 0.0007 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0049 0.0327
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0009 0.001 0.0066
Leishmania major hypothetical protein, conserved 0.0023 0.006 0.1407
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0044 0.0044
Echinococcus granulosus insulin receptor 0.0086 0.0296 0.0296
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0007 0.0001 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0251 0.6769
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0037 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0371 0.1691
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0294 0.1979
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0094
Echinococcus granulosus nuclear receptor nhr 48 0.0009 0.001 0.001
Brugia malayi glutathione reductase 0.0048 0.0154 0.1037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0001 0.0004
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0062 0.0124
Echinococcus granulosus c src tyrosine kinase 0.001 0.0013 0.0013
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0044 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Brugia malayi steroid hormone receptor 0.002 0.0049 0.0327
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0093 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0049 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Toxoplasma gondii exonuclease III APE 0.0019 0.0044 0.075
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0045 0.0045
Brugia malayi Protein kinase domain containing protein 0.0086 0.0296 0.1988
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0045
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0049 0.0327
Brugia malayi hypothetical protein 0.0035 0.0107 0.0717
Toxoplasma gondii thioredoxin reductase 0.0048 0.0154 0.2624
Brugia malayi TAR-binding protein 0.0061 0.0203 0.1365
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0007 0.0001 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0371 0.0768
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0141 0.2392
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0124
Entamoeba histolytica hypothetical protein 0.0012 0.002 0.0089
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0094
Mycobacterium ulcerans hypothetical protein 0.0023 0.0062 0.0124
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.001 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0049 0.0327
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0075 0.2015
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0049 0.0049
Trypanosoma cruzi ISWI complex protein 0.0009 0.0009 0.0233
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0046 0.0208
Echinococcus granulosus tyrosine protein kinase Lyn 0.0011 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Schistosoma mansoni tyrosine kinase 0.0204 0.0731 0.0731
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0045 0.0141 0.0282
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0123 0.0431 0.0431
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.005 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0075 0.0341
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0204
Echinococcus multilocularis epidermal growth factor receptor 0.0204 0.0731 0.0731
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0001 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Mycobacterium ulcerans acetyl-CoA synthetase 0.0007 0.0001 0.0001
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0045 0.03
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Echinococcus multilocularis tyrosine protein kinase Src64B 0.001 0.0013 0.0013
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0009 0.001 0.001
Schistosoma mansoni tyrosine kinase 0.0086 0.0296 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0049 0.0327
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0001 0.0004
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0019 0.0044 0.031
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0082 0.0374
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0204
Onchocerca volvulus 0.005 0.016 0.0945
Brugia malayi Cytochrome P450 family protein 0.0026 0.007 0.0472
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0001 0.0015
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0044 0.1699
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0001 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0045 0.0045
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0154 0.1037
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0203 0.1365
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0073 0.071
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0062 0.0062
Brugia malayi Trypsin family protein 0.005 0.016 0.1077
Plasmodium vivax glutathione reductase, putative 0.0048 0.0154 0.3177
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Schistosoma mansoni tyrosine kinase 0.001 0.0013 0.0013
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0048 0.032
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0338 0.2272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0049 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Brugia malayi nuclear hormone receptor family member nhr-6 0.0009 0.001 0.0066
Brugia malayi PXA domain containing protein 0.0019 0.0045 0.03
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0626
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0338 0.1993
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0037 0.0757
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.0001 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0049 0.0327
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Schistosoma mansoni polycystin 1-related 0.0137 0.0484 0.0484
Echinococcus multilocularis growth factor receptor bound protein 2 0.0007 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0044 0.0201
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0107 0.0107
Echinococcus granulosus arachidonate 5 lipoxygenase 0.076 0.2796 0.2796
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0338 0.1542
Echinococcus multilocularis lipoxygenase domain containing protein 0.0137 0.0484 0.0484
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.0431 0.0431
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0371 0.0742
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0371 0.1691
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0075 0.127
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0007 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0062 0.0124
Loa Loa (eye worm) nuclear hormone receptor 0.0009 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0072 0.0241 0.162
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0338 0.0338
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0338 0.7907
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0046 0.1232
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0371 0.1691
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1352 0.4993 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0046 0.0095
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.075
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0162 0.0324
Brugia malayi phosphofructokinase 0.0107 0.0371 0.2491
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0251 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Echinococcus multilocularis Mastin 0.005 0.016 0.016
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0045 0.0045
Schistosoma mansoni tyrosine kinase 0.0201 0.072 0.072
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0429 0.089
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0062 0.0128
Schistosoma mansoni cytochrome P450 0.0007 0.0001 0.0001
Brugia malayi Thioredoxin reductase 0.0048 0.0154 0.1037
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0151 0.1018
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Echinococcus granulosus transmembrane protease serine 3 0.005 0.016 0.016
Schistosoma mansoni lipoxygenase 0.076 0.2796 0.2796
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Brugia malayi nuclear receptor NHR-88 0.0009 0.001 0.0066
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0338 0.2272
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0081 0.0542
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0338 0.9122
Schistosoma mansoni lipoxygenase 0.0513 0.1879 0.1879
Echinococcus multilocularis c src tyrosine kinase 0.001 0.0013 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0049 0.0049
Echinococcus multilocularis epidermal growth factor receptor 0.0275 0.0995 0.0995
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0062 0.0124
Echinococcus multilocularis 0.0007 0.0001 0.0001
Onchocerca volvulus 0.006 0.0198 0.1168
Onchocerca volvulus 0.0007 0.0001 0.0003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0162 0.0335
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.1003
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.0642
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0007 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Schistosoma mansoni nuclear receptor nhr-48 0.0009 0.001 0.001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0037 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0371 0.1691
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0062 0.0062
Toxoplasma gondii histone lysine methyltransferase SET1 0.0165 0.0588 1
Brugia malayi Trypsin family protein 0.005 0.016 0.1077
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0007 0.0001 0.0002
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0154 0.0154
Entamoeba histolytica hypothetical protein 0.0035 0.0107 0.0486
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0037 0.1003
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0371 0.0371
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0049 0.0049
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0007 0.0001 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0251 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0024 0.0641
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0408 0.1488 1
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0001 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0049 0.0327
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0045 0.0045
Plasmodium vivax amine transporter, putative 0.0019 0.0044 0.09
Loa Loa (eye worm) RNA binding protein 0.0061 0.0203 0.1365
Plasmodium falciparum zinc finger protein, putative 0.001 0.0013 0.0253
Brugia malayi hypothetical protein 0.001 0.0014 0.0094
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0037 0.0074
Brugia malayi orphan nuclear receptor NR2E1 0.0009 0.001 0.0066
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0371 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0384 0.0795
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0384 0.0795
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0007 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Leishmania major cytochrome p450-like protein 0.0007 0.0001 0.002
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0371 0.1691
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.1003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0093 0.0093
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0007 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0014 0.0094
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0014 0.0014
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.005 0.016 0.016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0384 0.0795
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0384 0.0795
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.005 0.016 0.016
Schistosoma mansoni nuclear hormone receptor 0.0009 0.001 0.001
Schistosoma mansoni rab6-interacting 0.0137 0.0484 0.0484
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0049 0.0327
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0251 0.1145
Echinococcus granulosus NCK adaptor protein 0.0007 0.0002 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0014 0.0064
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0045 0.0045
Onchocerca volvulus 0.0137 0.0484 0.2856
Leishmania major cytochrome p450-like protein 0.0007 0.0001 0.002
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0044 0.09
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0049 0.0049
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0139 0.3745
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0082 0.0374
Loa Loa (eye worm) trypsin family protein 0.005 0.016 0.1077
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.026 0.026
Brugia malayi SRC-1 0.001 0.0013 0.0087
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.0044 0.0044
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.0268
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0045 0.0141 0.0642
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0062 0.0128
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0047 0.0216
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0009 0.001 0.001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0082 0.1683
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0371 0.0371
Brugia malayi hypothetical protein 0.0072 0.0241 0.162
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0062 0.1445
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0045 0.0141 0.0945
Brugia malayi SET domain containing protein 0.0009 0.0008 0.0055
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0001 0.0015
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0007 0.0001 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0155 0.055 0.055
Entamoeba histolytica hypothetical protein 0.0035 0.0107 0.0486
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0001 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0049 0.0049
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0251 0.1686
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0107 0.0107
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0203 0.1365
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0037 0.0757
Brugia malayi Muscleblind-like protein 0.0301 0.1093 0.7342
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0075 0.0502
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.0044 0.0044
Brugia malayi hypothetical protein 0.0137 0.0484 0.3255
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0045
Brugia malayi hypothetical protein 0.0019 0.0044 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0014 0.0014
Brugia malayi nuclear hormone receptor 0.0009 0.001 0.0066
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0001 0.0015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0142 0.0142
Echinococcus granulosus expressed protein 0.0365 0.1329 0.1329
Brugia malayi nuclear hormone receptor family member odr-7 0.0009 0.001 0.0066
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0428 0.0857
Entamoeba histolytica hypothetical protein 0.001 0.0013 0.0058
Brugia malayi Doublecortin family protein 0.0137 0.0484 0.3255
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0007 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0024 0.0641
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0046 0.0046
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.1366
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Schistosoma mansoni myst-related protein 0.001 0.0013 0.0013
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0075 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0007 0.0001 0.0002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0044 0.0901
Echinococcus granulosus tyrosine protein kinase Src64B 0.001 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0007 0.0001 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0062 0.0062
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.006 0.1623
Loa Loa (eye worm) glutathione reductase 0.0048 0.0154 0.1037
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0001 0.0013
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0045 0.0141 0.0642
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0044 0.0297
Loa Loa (eye worm) hypothetical protein 0.0301 0.1093 0.7342
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0428 0.0857
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0348 0.2339
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.103 0.4697
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.001 0.0013 0.0013
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0371 0.0742
Schistosoma mansoni SET domain protein 0.0009 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0198 0.0198
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0045 0.0045
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0046 0.0307
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0009 0.001 0.001
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0075 0.1747
Echinococcus granulosus dna polymerase kappa 0.0019 0.0046 0.0046
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.005 0.016 0.1077
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0586 0.0586
Echinococcus multilocularis tyrosine protein kinase Abl 0.001 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.005 0.016 0.016
Schistosoma mansoni hypothetical protein 0.0048 0.0151 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.002 0.0528
Echinococcus multilocularis dnaJ subfamily B 0.1226 0.4524 0.4524
Brugia malayi hypothetical protein 0.001 0.0014 0.0094
Loa Loa (eye worm) oxidoreductase 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0123 0.0431 0.2894
Plasmodium falciparum transporter, putative 0.0019 0.0044 0.09
Entamoeba histolytica hypothetical protein 0.0012 0.002 0.0089
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.087
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0007 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0047 0.0216
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.001 0.0013 0.0013
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0037 0.087
Loa Loa (eye worm) serotonin transporter b 0.0019 0.0044 0.0296
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0007 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0007 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0048
Onchocerca volvulus 0.005 0.016 0.0945
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0044 0.0044
Onchocerca volvulus 0.0009 0.001 0.0058
Loa Loa (eye worm) SRC-1 0.001 0.0013 0.0087
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0007 0.0001 0.0001
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0384 0.0769
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.023 0.1546
Plasmodium falciparum amino acid transporter, putative 0.0019 0.0044 0.09
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0049 0.0287
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.009 0.1533
Echinococcus granulosus lipoxygenase domain containing protein 0.0137 0.0484 0.0484
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0162 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0203 0.0203
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0086 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.103 1
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0046 0.1232
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0142 0.0142
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0001 0.0003
Schistosoma mansoni survival motor neuron protein 0.0048 0.0151 0.0151
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0.0001 0.0015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0093 0.0093
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0045 0.0045
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0007 0.0002 0.0002
Brugia malayi Pre-SET motif family protein 0.0408 0.1488 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0046 0.0208
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0007 0.0001 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0044 0.0296
Mycobacterium ulcerans hypothetical protein 0.005 0.016 0.0321
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0047 0.0216
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0049 0.0049
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0045 0.0045
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.016 0.016
Brugia malayi Trypsin family protein 0.005 0.016 0.1077
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.1003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0198 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0007 0.0001 0.0002
Onchocerca volvulus 0.0137 0.0484 0.2856
Schistosoma mansoni DNA polymerase eta 0.0044 0.0139 0.0139
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Giardia lamblia Kinase, PLK 0.0098 0.0338 0.3284
Echinococcus granulosus lipoxygenase domain containing protein 0.0137 0.0484 0.0484
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.002 0.0528
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0045 0.03
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0371 0.2491
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0296
Echinococcus granulosus FTZ F1 alpha 0.002 0.0049 0.0049
Echinococcus granulosus dnaJ subfamily B 0.1226 0.4524 0.4524
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0371 0.1691
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0203 0.1365
Schistosoma mansoni hypothetical protein 0.0032 0.0093 0.0093
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0045 0.0045
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0049 0.0327
Brugia malayi nuclear receptor NHR-88 0.002 0.0049 0.0327
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0062 0.0062
Schistosoma mansoni thyroid hormone receptor 0.002 0.0049 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0049 0.0327
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0007 0.0001 0.0002
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0045 0.0045
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0001 0.0001
Echinococcus multilocularis serotonin transporter 0.0019 0.0044 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.1003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.001 0.0058
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0203 0.0203
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0049 0.0049
Schistosoma mansoni growth factor receptor-bound protein 0.0007 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0036 0.0075
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0141 0.0282
Echinococcus granulosus tar DNA binding protein 0.0061 0.0203 0.0203
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.0044 0.0044
Plasmodium falciparum LCCL domain-containing protein 0.0137 0.0484 1
Brugia malayi CXXC zinc finger family protein 0.0086 0.0294 0.1979
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.001 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0049 0.0327
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0142 0.0142
Schistosoma mansoni myst-related protein 0.001 0.0013 0.0013
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0001 0.0015
Schistosoma mansoni protein kinase 0.0155 0.055 0.055
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0162 0.0335
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0165 0.0586 0.3937
Loa Loa (eye worm) hypothetical protein 0.005 0.016 0.1077
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0062 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0049 0.0049
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0048 0.032
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0001 0.0023
Brugia malayi hypothetical protein 0.0233 0.084 0.5643
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0007 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.001 0.0013 0.0013
Loa Loa (eye worm) cytochrome P450 0.0007 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0327
Echinococcus multilocularis lipoxygenase domain containing protein 0.0137 0.0484 0.0484
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0007 0.0001 0.0002
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0082 0.0374
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0044 0.0044
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0013 0.0013
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0371 0.2491
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0045 0.03
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0045 0.0045

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 36 mg kg-1 Anticonvulsant activity measured by the inhibition of DMCM-induced seizures in mice. ChEMBL. 10543872
IC50 (binding) = 659 nM In vitro inhibition of [3H]-GABA uptake in rat synaptosomes ChEMBL. 10543872

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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