Detailed information for compound 376858

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1615.45 | Formula: C71H101Cl2NO36
  • H donors: 9 H acceptors: 10 LogP: 1 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: COC[C@H]1O[C@@H](O[C@@H]2OC[C@H]3[C@H]([C@H]2O)O[C@@]2(O3)OC[C@H]([C@H]3[C@H]2OCO3)OC(=O)c2c(C)cc(cc2O)O)[C@H]([C@H]([C@@H]1O[C@@H]1O[C@H](C)[C@@H]([C@@H]([C@@]1(C)O)O[C@@H]1O[C@H](C)[C@@H]2[C@]([C@@H]1O)(C)O[C@]1(O2)C[C@@H](O)[C@@H]([C@H](O1)C)O[C@@H]1O[C@H](C)[C@H]([C@@H](C1)O[C@@H]1O[C@@H](C)[C@@H]([C@@](C1)(C)N)OC)OC(=O)c1c(C)c(Cl)c(c(c1OC)Cl)O)OC)O)OC
  • InChi: 1S/C71H101Cl2NO36/c1-25-16-32(75)17-33(76)41(25)61(82)99-37-23-93-71(60-53(37)91-24-92-60)107-38-22-90-63(47(80)52(38)108-71)105-64-55(88-14)46(79)51(36(100-64)21-85-11)103-66-68(9,84)59(50(86-12)28(4)97-66)104-65-56(81)69(10)58(31(7)96-65)109-70(110-69)19-34(77)48(29(5)106-70)101-39-18-35(98-40-20-67(8,74)57(89-15)30(6)95-40)49(27(3)94-39)102-62(83)42-26(2)43(72)45(78)44(73)54(42)87-13/h16-17,27-31,34-40,46-53,55-60,63-66,75-81,84H,18-24,74H2,1-15H3/t27-,28-,29-,30+,31-,34-,35-,36-,37-,38+,39+,40+,46+,47-,48-,49-,50+,51-,52-,53+,55+,56-,57+,58-,59+,60-,63+,64+,65+,66+,67+,68-,69-,70-,71-/m1/s1
  • InChiKey: JPZKVAKTNVAEDV-SODCRVAISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Glutaredoxin protein 5 0.0067 0.0099 0.123
Trichomonas vaginalis STE family protein kinase 0.0044 0.0052 0.1916
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0042 0.0047 0.0578
Loa Loa (eye worm) AUR protein kinase 0.0046 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0152 0.0152
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0044 0.0052 0.0642
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.01 0.125
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0036 0.0036 0.0428
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0212 0.0396 0.495
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0037 0.0038 0.0473
Echinococcus multilocularis serine:threonine protein kinase 0.006 0.0084 0.1034
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0084 0.0134 0.1675
Schistosoma mansoni protein kinase 0.0106 0.0178 0.0178
Brugia malayi Temporarily assigned gene name protein 59 0.0061 0.0086 0.0854
Echinococcus granulosus myotubularin protein 13 0.0026 0.0015 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0128 0.4692
Schistosoma mansoni serine/threonine-protein kinase 0.0086 0.0138 0.0138
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0099
Onchocerca volvulus 0.0104 0.0174 0.2181
Echinococcus multilocularis cyclin dependent kinase 5 0.0062 0.0089 0.1099
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0127 0.0222 0.2767
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0141 0.0251 0.0251
Brugia malayi Protein kinase c protein 2 0.006 0.0086 0.0849
Echinococcus granulosus serine:threonine protein kinase N2 0.007 0.0106 0.1313
Entamoeba histolytica cell division protein kinase 2, putative 0.0062 0.0089 0.1112
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0052 0.0069 0.0848
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0218 0.0218
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0408 0.0798 0.7934
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0408 0.0798 0.0798
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.005 0.1823
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0043 0.005 0.0622
Brugia malayi P38 map kinase family protein 2 0.0084 0.0134 0.133
Brugia malayi protein kinase C II. 0.0105 0.0176 0.1749
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0194 0.0194
Trichomonas vaginalis CK1 family protein kinase 0.0057 0.0078 0.2841
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0025 0.0012 0.0152
Entamoeba histolytica protein kinase, putative 0.0033 0.0028 0.0352
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0408 0.0798 1
Schistosoma mansoni fad oxidoreductase 0.0408 0.0798 0.0798
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0176 0.0176
Schistosoma mansoni protein kinase 0.0102 0.0171 0.0171
Schistosoma mansoni netrin receptor unc5 0.0019 0.0001 0.0001
Echinococcus granulosus unc 13 munc13 0.0023 0.001 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Echinococcus multilocularis dual specificity 0.0064 0.0093 0.1147
Echinococcus granulosus tyrosine protein kinase Src64B 0.0026 0.0014 0.0163
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0052 0.0069 0.0849
Trypanosoma cruzi cdc2-related kinase 1 0.0062 0.0089 0.1112
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.0005 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0056 0.0056
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0408 0.0798 1
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0043 0.0049 0.0614
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0008 0.0099
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0007 0.0007
Echinococcus multilocularis casein kinase I delta 0.0057 0.0078 0.0957
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0037 0.0038 0.0473
Echinococcus granulosus calcium dependent protein kinase 0.0037 0.0037 0.045
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0083 0.0131 0.1628
Entamoeba histolytica protein kinase, putative 0.0081 0.0128 0.1602
Brugia malayi Protein kinase domain containing protein 0.0197 0.0365 0.363
Onchocerca volvulus 0.0169 0.0309 0.3876
Brugia malayi protein unc-22 0.0022 0.0008 0.0074
Echinococcus granulosus casein kinase I delta 0.0057 0.0078 0.0958
Echinococcus granulosus casein kinase I gamma 0.0113 0.0194 0.242
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Trypanosoma cruzi casein kinase, putative 0.0057 0.0078 0.097
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0044 0.0051 0.0635
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.001 0.0102
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0197 0.0365 0.4566
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0116 0.0199 0.1978
Brugia malayi Protein kinase domain containing protein 0.0064 0.0093 0.0921
Echinococcus granulosus NDR protein kinase 0.0081 0.0128 0.1591
Echinococcus granulosus expressed protein 0.0043 0.0049 0.0601
Brugia malayi diacylglycerol kinase 0.0023 0.0008 0.008
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0061 0.0086 0.0086
Schistosoma mansoni ste20-related kinase 0.0109 0.0185 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Loa Loa (eye worm) hypothetical protein 0.0046 0.0056 0.0056
Loa Loa (eye worm) AGC/PKG protein kinase 0.0025 0.0012 0.0012
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0408 0.0798 0.7934
Loa Loa (eye worm) hypothetical protein 0.0037 0.0038 0.0038
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0037 0.0038 0.0473
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0128 0.468
Echinococcus granulosus rho-associated protein kinase 1 0.0174 0.0319 0.3985
Schistosoma mansoni tyrosine kinase 0.0075 0.0116 0.0116
Echinococcus multilocularis 0.0081 0.0127 0.1579
Schistosoma mansoni protein kinase 0.0046 0.0056 0.0056
Brugia malayi MAP kinase sur-1 0.0043 0.005 0.0495
Brugia malayi Stress-activated protein kinase jnk-1 0.0141 0.0251 0.2494
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0189 0.0349 0.4368
Loa Loa (eye worm) TK/INSR protein kinase 0.0102 0.0171 0.0171
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0144 0.0258 0.3227
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0087 0.0139 0.0139
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0068 0.0851
Trypanosoma cruzi polo-like protein kinase, putative 0.0144 0.0258 0.3227
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0056 0.2047
Entamoeba histolytica protein kinase, putative 0.0064 0.0093 0.116
Echinococcus multilocularis casein kinase I alpha 0.0057 0.0078 0.0957
Trypanosoma brucei Casein kinase II 0.0052 0.0068 0.0851
Echinococcus multilocularis cyclin dependent kinase 1 0.0062 0.0089 0.1099
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0043 0.0049 0.0614
Trichomonas vaginalis CK1 family protein kinase 0.0057 0.0078 0.2841
Brugia malayi Protein kinase domain containing protein 0.0043 0.0049 0.0488
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0124 0.0215 0.0215
Schistosoma mansoni protein kinase 0.0052 0.0068 0.0068
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0081 0.0128 0.1591
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0057 0.0078 0.0078
Schistosoma mansoni protein kinase C 0.0023 0.001 0.001
Brugia malayi serine/threonine protein kinase 6 0.0046 0.0056 0.0556
Brugia malayi serine/threonine-protein kinase 6 0.0046 0.0056 0.0556
Echinococcus granulosus serine/threonine protein kinase 0.0086 0.0138 0.1715
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0067 0.01 0.125
Toxoplasma gondii AGC kinase 0.0148 0.0266 0.3329
Trypanosoma cruzi NIMA-related kinase, putative 0.0025 0.0013 0.0162
Trypanosoma brucei cdc2-related kinase 1 0.0062 0.0089 0.1112
Trichomonas vaginalis STE family protein kinase 0.0044 0.0052 0.1916
Echinococcus multilocularis titin 0.0022 0.0008 0.0077
Schistosoma mansoni kinase 0.0154 0.0278 0.0278
Echinococcus multilocularis dual specificity 0.0073 0.0111 0.1381
Echinococcus multilocularis hypothetical protein 0.0033 0.003 0.0355
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0067 0.0099 0.123
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Plasmodium falciparum calcium-dependent protein kinase 2 0.0052 0.0069 0.0861
Onchocerca volvulus 0.0078 0.0121 0.151
Echinococcus multilocularis casein kinase ii subunit alpha 0.0052 0.0068 0.0838
Giardia lamblia Kinase, CMGC MAPK 0.0043 0.005 0.0469
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0073 0.0111 0.1394
Schistosoma mansoni protein kinase 0.0033 0.0028 0.0028
Mycobacterium ulcerans D-amino acid oxidase Aao 0.489 1 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0043 0.005 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Toxoplasma gondii NEK kinase 0.0025 0.0013 0.0162
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0098 0.0972
Trichomonas vaginalis STE family protein kinase 0.0071 0.0108 0.3965
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.0459
Echinococcus multilocularis cyclin dependent kinase 0.0062 0.0089 0.1099
Brugia malayi Protein kinase domain containing protein 0.0241 0.0456 0.4535
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0047 0.173
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0087 0.0139 0.0139
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0083 0.0131 0.164
Echinococcus granulosus tyrosine protein kinase Blk 0.0024 0.001 0.0111
Schistosoma mansoni hypothetical protein 0.0033 0.003 0.003
Entamoeba histolytica protein kinase, putative 0.0052 0.0069 0.0861
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0408 0.0798 1
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0027 0.0017 0.0173
Schistosoma mansoni tyrosine kinase 0.0119 0.0205 0.0205
Schistosoma mansoni protein kinase 0.0233 0.044 0.044
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0083 0.0131 0.164
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.006 0.0084 0.0084
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0041 0.0046 0.0572
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0062 0.0089 0.0089
Entamoeba histolytica protein kinase, putative 0.0036 0.0035 0.0438
Echinococcus multilocularis fibroblast growth factor receptor 4 0.006 0.0084 0.1033
Echinococcus multilocularis mitogen activated protein kinase 14 0.0084 0.0134 0.1663
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.018 0.018
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0189 0.0349 0.4368
Brugia malayi Fes/CIP4 homology domain containing protein 0.0041 0.0046 0.0452
Loa Loa (eye worm) TK protein kinase 0.0024 0.001 0.001
Echinococcus multilocularis twitchin 0.0022 0.0008 0.0077
Loa Loa (eye worm) hypothetical protein 0.0408 0.0798 0.0798
Loa Loa (eye worm) thyroid receptor interactor 0.0041 0.0046 0.0046
Onchocerca volvulus 0.0022 0.0008 0.0093
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0189 0.0349 0.3472
Leishmania major serine/threonine-protein kinase, putative 0.0025 0.0013 0.0162
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0126 0.022 0.2747
Plasmodium falciparum calcium-dependent protein kinase 1 0.0052 0.0069 0.0861
Onchocerca volvulus 0.0075 0.0116 0.1454
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Brugia malayi serine/threonine-protein kinase PAK 7 0.0124 0.0215 0.2138
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0251 0.0251
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0408 0.0798 1
Echinococcus multilocularis calcium dependent protein kinase 0.0037 0.0037 0.0449
Echinococcus multilocularis tyrosine protein kinase Blk 0.0024 0.001 0.011
Echinococcus granulosus netrin receptor unc 5 0.0019 0.0001 0.0001
Echinococcus multilocularis cyclin dependent kinase 19 0.0087 0.0139 0.1732
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0025 0.0013 0.0162
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0052 0.0069 0.0848
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0022 0.0006 0.006
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0064 0.0093 0.116
Brugia malayi protein kinase C3,putative 0.0083 0.0132 0.1314
Echinococcus granulosus voltage gated potassium channel 0.002 0.0003 0.0025
Brugia malayi STE20-like kinase MST 0.0137 0.0243 0.2412
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.002 0.0003 0.0032
Echinococcus granulosus dual specificity 0.0073 0.0111 0.1382
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0021
Trypanosoma cruzi casein kinase, putative 0.0057 0.0078 0.097
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0408 0.0798 1
Entamoeba histolytica protein kinase , putative 0.0046 0.0056 0.0699
Leishmania major casein kinase II, putative 0.0052 0.0068 0.0851
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0083 0.0131 0.1629
Brugia malayi Protein kinase domain containing protein 0.0107 0.018 0.1791
Echinococcus granulosus mitogen activated protein kinase 11 0.0084 0.0134 0.1664
Echinococcus multilocularis N chimaerin 0.0025 0.0012 0.0137
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0046 0.0056 0.0686
Schistosoma mansoni protein kinase 0.0106 0.0178 0.0178
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0012 0.0139
Plasmodium falciparum casein kinase 2, alpha subunit 0.0052 0.0068 0.0851
Schistosoma mansoni protein kinase 0.0141 0.0252 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0021 0.0749
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0044 0.0051 0.0635
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0098 0.0164 0.1625
Onchocerca volvulus Tyrosine kinase homolog 0.0182 0.0335 0.4201
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0319 0.0319
Plasmodium falciparum casein kinase 1 0.0057 0.0078 0.097
Loa Loa (eye worm) TK protein kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.025 0.0476 0.0476
Trypanosoma cruzi polo-like protein kinase, putative 0.0144 0.0258 0.3227
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0141 0.0251 0.3133
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0488 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0061 0.2246
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0061 0.0087 0.0087
Echinococcus granulosus mitogen activated protein kinase 3 0.0043 0.005 0.061
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0052 0.0069 0.0861
Echinococcus granulosus aurora kinase A 0.0046 0.0056 0.0686
Brugia malayi RE18450p 0.0408 0.0798 0.7934
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0052 0.0069 0.0861
Echinococcus granulosus serine:threonine protein kinase 0.006 0.0084 0.1034
Brugia malayi Protein kinase domain containing protein 0.0102 0.0171 0.1703
Trypanosoma brucei RNA helicase, putative 0.0242 0.0458 0.5738
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0073 0.0111 0.1107
Echinococcus granulosus casein kinase I alpha 0.0057 0.0078 0.0958
Trichomonas vaginalis STE family protein kinase 0.0033 0.0028 0.1029
Giardia lamblia Kinase, PLK 0.0144 0.0258 0.3116
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Echinococcus granulosus protein kinase shaggy 0.0067 0.01 0.1238
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0046 0.0056 0.0688
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0046 0.0056 0.0702
Trypanosoma cruzi cdc2-related kinase 1 0.0062 0.0089 0.1112
Echinococcus granulosus tyrosine protein kinase HCK 0.0022 0.0006 0.0058
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0043 0.005 0.0622
Giardia lamblia Kinase, STE STE20 0.0044 0.0051 0.0482
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0096 0.3527
Echinococcus multilocularis mitogen activated protein kinase 14 0.0084 0.0134 0.1663
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0052 0.0069 0.0861
Loa Loa (eye worm) hypothetical protein 0.01 0.0167 0.0167
Echinococcus granulosus RNA directed DNA polymerase 0.0027 0.0017 0.0196
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0408 0.0798 1
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0118 0.0204 0.2545
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0089 0.3256
Leishmania major protein kinase, putative 0.0021 0.0005 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0013 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0111 0.0111
Echinococcus granulosus cGMP dependent protein kinase 0.0025 0.0012 0.0139
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0003 0.0025
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0064 0.0093 0.116
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0043 0.005 0.0622
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0128 0.4692
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0128 0.4692
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0408 0.0798 1
Trypanosoma cruzi casein kinase, putative 0.0057 0.0078 0.097
Echinococcus multilocularis epidermal growth factor receptor 0.0119 0.0205 0.2555
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0144 0.0258 0.3217
Brugia malayi Casein kinase II, alpha chain 0.0052 0.0068 0.0676
Echinococcus multilocularis rho associated protein kinase 0.0174 0.0319 0.3984
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0008 0.0008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0043 0.005 0.0609
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0125 0.0218 0.2724
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0061 0.0086 0.1062
Giardia lamblia Kinase, NEK 0.0071 0.0108 0.1212
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0408 0.0798 1
Onchocerca volvulus 0.01 0.0167 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0056 0.0056
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0177 0.0326 0.0326
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0064 0.0093 0.116
Brugia malayi Protein kinase domain containing protein 0.0031 0.0026 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0097 0.3566
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0052 0.0069 0.0861
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0076 0.0118 0.1463
Echinococcus granulosus nervana 2 0.0067 0.0099 0.123
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Leishmania major protein kinase, putative 0.0025 0.0013 0.0162
Echinococcus granulosus dual specificity 0.0073 0.0111 0.1382
Echinococcus granulosus protein kinase c epsilon type 0.0105 0.0176 0.2193
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0047 0.173
Brugia malayi Egg laying defective protein 4 0.0025 0.0012 0.0122
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0118 0.0204 0.0204
Loa Loa (eye worm) SRC-1 0.0026 0.0014 0.0014
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0073 0.0111 0.1394
Trypanosoma brucei polo-like protein kinase 0.0144 0.0258 0.3227
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0044 0.0052 0.0641
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0258 0.0258
Echinococcus granulosus Protein kinase C brain isozyme 0.0126 0.022 0.2748
Leishmania major protein kinase, putative 0.0025 0.0012 0.0152
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0081 0.0128 0.1598
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0408 0.0798 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0033 0.003 0.003
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0081 0.0127 0.0127
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0052 0.0069 0.0861
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0022 0.0007 0.008
Toxoplasma gondii AGC kinase 0.0037 0.0038 0.0473
Schistosoma mansoni tyrosine kinase 0.006 0.0084 0.0084
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0043 0.005 0.0622
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0052 0.0068 0.0851
Giardia lamblia Kinase, AGC PKA 0.0083 0.0131 0.1503
Echinococcus granulosus serine:threonine protein kinase N2 0.0152 0.0273 0.3404
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0014 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.005 0.1823
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0212 0.0396 0.495
Loa Loa (eye worm) protein kinase domain-containing protein 0.0113 0.0194 0.0194
Trypanosoma brucei protein kinase, putative 0.0021 0.0005 0.0061
Trypanosoma brucei cdc2-related kinase 3 0.0062 0.0089 0.1112
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0108 0.0182 0.2271
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0043 0.005 0.0622
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0189 0.0349 0.0349
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0107 0.018 0.2245
Giardia lamblia Kinase, CMGC CK2 0.0052 0.0068 0.0701
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0012 0.0139
Plasmodium falciparum protein serine/threonine kinase-1 0.0081 0.0128 0.1598
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0056 0.0699
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0241 0.0241
Giardia lamblia Kinase, CMGC CDK 0.0062 0.0089 0.0966
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0017 0.0017
Brugia malayi Doublecortin family protein 0.0079 0.0125 0.1238
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0017 0.0017
Echinococcus multilocularis casein kinase i 0.0057 0.0078 0.0957
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0052 0.0069 0.0848
Brugia malayi intracellular kinase 0.0067 0.01 0.0993
Entamoeba histolytica protein kinase, putative 0.0036 0.0036 0.0443
Echinococcus multilocularis mitogen activated protein kinase 0.0043 0.005 0.0609
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.0005 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0038 0.0038
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0022 0.0006 0.006
Echinococcus granulosus hypothetical protein 0.0065 0.0096 0.1188
Brugia malayi Protein kinase domain 0.0044 0.0052 0.052
Entamoeba histolytica cell division protein kinase 2, putative 0.0062 0.0089 0.1112
Echinococcus multilocularis serine threonine protein kinase 0.0103 0.0174 0.2162
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0026 0.0014 0.0163
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.046
Schistosoma mansoni protein kinase 0.0081 0.0127 0.0127
Giardia lamblia Kinase, CMGC CDK 0.0062 0.0089 0.0966
Schistosoma mansoni tyrosine kinase 0.0081 0.0128 0.0128
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0093 0.0152 0.1889
Echinococcus multilocularis 0.0065 0.0096 0.1187
Echinococcus multilocularis serine:threonine protein kinase 38 0.0081 0.0128 0.159
Loa Loa (eye worm) TK/EGFR protein kinase 0.0119 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0078 0.0121 0.0121
Giardia lamblia Kinase, STE STE20 0.0044 0.0052 0.0501
Echinococcus multilocularis nervana 2 0.0067 0.0099 0.1229
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Plasmodium vivax serine/threonine kinase-1, putative 0.0081 0.0128 0.1598
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0087 0.0139 0.1733
Echinococcus multilocularis neuroglian 0.0023 0.0008 0.0081
Plasmodium vivax calcium-dependent protein kinase, putative 0.0052 0.0069 0.0861
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0067 0.01 0.01
Schistosoma mansoni d-amino acid oxidase 0.489 1 1
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0081 0.0128 0.1598
Leishmania major protein kinase, putative 0.0046 0.0056 0.0699
Echinococcus multilocularis mitogen activated protein kinase 11 0.0084 0.0134 0.1663
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0047 0.0057 0.0057
Brugia malayi Serine/threonine-protein kinase SULU 0.0118 0.0204 0.2029
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0137 0.0243 0.0243
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0233 0.044 0.5505
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.0459
Loa Loa (eye worm) hypothetical protein 0.006 0.0084 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Giardia lamblia Kinase, AGC PKA 0.0037 0.0038 0.0316
Entamoeba histolytica protein kinase, putative 0.0043 0.0049 0.0614
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Trypanosoma brucei SNF1-related protein kinases, putative 0.0046 0.0056 0.0702
Loa Loa (eye worm) TK protein kinase 0.0066 0.0098 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0007 0.0073
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0067 0.01 0.1238
Brugia malayi Pleckstrin Homology Domain 0.0026 0.0015 0.0148
Entamoeba histolytica protein kinase, putative 0.0046 0.0056 0.0699
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0096 0.3527
Brugia malayi hypothetical protein 0.0031 0.0024 0.0242
Trypanosoma cruzi cdc2-related kinase 3 0.0062 0.0089 0.1112
Onchocerca volvulus 0.0061 0.0086 0.1076
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0046 0.0056 0.0702
Brugia malayi Protein kinase domain containing protein 0.0152 0.0273 0.271
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0081 0.0128 0.1598
Echinococcus granulosus protein kinase C gamma type 0.0103 0.0174 0.2163
Echinococcus granulosus activin receptor type 0.0021 0.0005 0.0047
Echinococcus granulosus casein kinase I delta 0.0057 0.0078 0.0958
Brugia malayi Protein kinase domain containing protein 0.0081 0.0128 0.1272
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0108 0.3965
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0212 0.0396 0.0396
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus multilocularis nervana 2 0.0067 0.0099 0.1229
Toxoplasma gondii hypothetical protein 0.0408 0.0798 1
Plasmodium vivax unspecified product 0.0052 0.0068 0.0851
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.1383
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0079 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.003
Schistosoma mansoni unc-13 (munc13) 0.0023 0.001 0.001
Echinococcus granulosus roundabout 2 0.0026 0.0015 0.0178
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0046 0.0056 0.0699
Loa Loa (eye worm) hypothetical protein 0.0075 0.0116 0.0116
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0044 0.0052 0.0642
Entamoeba histolytica casein kinase, putative 0.0057 0.0078 0.097
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0013 0.0473
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0073 0.0111 0.1394
Echinococcus multilocularis tyrosine protein kinase HCK 0.0022 0.0006 0.0057
Onchocerca volvulus 0.0174 0.0319 0.3994
Giardia lamblia Kinase, CMGC GSK 0.0067 0.01 0.1106
Giardia lamblia Kinase, CMGC SRPK 0.0043 0.0049 0.046
Loa Loa (eye worm) hypothetical protein 0.0048 0.0061 0.0061
Echinococcus multilocularis 0.0035 0.0032 0.0389
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0081 0.0128 0.1591
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0026 0.0014 0.0162
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0021 0.0005 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0056 0.2047
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0014 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0061 0.0061
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0093 0.116
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0044 0.0051 0.0635
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0047 0.0047
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0066 0.0096 0.3525
Entamoeba histolytica protein kinase, putative 0.0053 0.007 0.0879
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0509 0.1006 0.1006
Giardia lamblia Aurora kinase 0.0046 0.0056 0.0546
Onchocerca volvulus Serine\/threonine kinase homolog 0.0144 0.0258 0.3228
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0241 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.01 0.366
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0056 0.0056
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0127 0.0222 0.2766
Echinococcus granulosus mitogen activated protein kinase 0.0043 0.005 0.061
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0156 0.0283 0.0283
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0067 0.01 0.125
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0043 0.0049 0.0614
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0027 0.0017 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.022 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0128 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0012 0.0012
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0024 0.001 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Loa Loa (eye worm) AGC/AKT protein kinase 0.0152 0.0273 0.0273
Entamoeba histolytica protein kinase, putative 0.0042 0.0047 0.0591
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0057 0.0078 0.097
Brugia malayi Protein kinase domain containing protein 0.0103 0.0172 0.1713
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0408 0.0798 1
Entamoeba histolytica protein kinase, putative 0.0152 0.0273 0.3415
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0026 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0038 0.0038
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0044 0.0052 0.0641
Schistosoma mansoni protein kinase C mu 0.0023 0.0008 0.0008
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0408 0.0798 0.0798
Schistosoma mansoni NAD dehydrogenase 0.0408 0.0798 0.0798
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0023 0.0008 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0061 0.0086 0.1063
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0144 0.0258 0.3227
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0008 0.0008
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0106 0.0178 0.2221
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0093 0.0152 0.0152
Entamoeba histolytica protein kinase, putative 0.0064 0.0093 0.116
Echinococcus granulosus mitogen activated protein kinase 14 0.0084 0.0134 0.1664
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0014 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus granulosus casein kinase i 0.0057 0.0078 0.0958
Entamoeba histolytica protein kinase, putative 0.0036 0.0036 0.0443
Trypanosoma brucei rac serine-threonine kinase, putative 0.0152 0.0273 0.3415
Toxoplasma gondii histone kinase SNF1, putative 0.0046 0.0056 0.0702
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0046 0.0056 0.0702
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0067 0.01 0.125
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0012 0.0138
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0061 0.0086 0.1075
Entamoeba histolytica serine/threonine protein kinase, putative 0.0046 0.0056 0.0702
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0037 0.0038 0.0473
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0093 0.0152 0.1889
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus multilocularis casein kinase I gamma 0.0113 0.0194 0.242
Brugia malayi Protein kinase domain containing protein 0.006 0.0084 0.0831
Schistosoma mansoni vesicular amine transporter 0.002 0.0003 0.0003
Trichomonas vaginalis STE family protein kinase 0.0044 0.0052 0.1916
Echinococcus multilocularis activin receptor type 0.0021 0.0005 0.0047
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0052 0.0069 0.0849
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.0128 0.1585
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0266 0.0507 0.635
Trichomonas vaginalis STE family protein kinase 0.0044 0.0052 0.1916
Brugia malayi phosphoinositide-dependent protein kinase I 0.0042 0.0047 0.047
Brugia malayi Cam kinase protein 1 0.0052 0.0069 0.0684
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0189 0.0349 0.0349
Schistosoma mansoni tyrosine kinase 0.0023 0.0008 0.0008
Schistosoma mansoni serine/threonine-protein kinase 0.0086 0.0138 0.0138
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0026 0.0014 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0012 0.0012
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0049 0.0061 0.0061
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0084 0.0134 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Leishmania major protein kinase A catalytic subunit isoform 1 0.0037 0.0038 0.0473
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0037 0.0038 0.0473
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0044 0.0052 0.0641
Plasmodium falciparum NIMA related kinase 1 0.0071 0.0108 0.1354
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0408 0.0798 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0025 0.0013 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Echinococcus multilocularis Rac GTPase activating protein 1 0.0023 0.0008 0.0085
Plasmodium falciparum protein kinase 5 0.0062 0.0089 0.1112
Loa Loa (eye worm) AGC/PKN protein kinase 0.0152 0.0273 0.0272
Loa Loa (eye worm) hypothetical protein 0.0044 0.0052 0.0052
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0046 0.0056 0.0699
Loa Loa (eye worm) AGC/PKA protein kinase 0.0037 0.0038 0.0038
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0093 0.0152 0.1888
Entamoeba histolytica protein kinase domain containing protein 0.0108 0.0182 0.2282
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0081 0.0128 0.1598
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0075 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0061 0.0086 0.0086
Plasmodium falciparum calcium-dependent protein kinase 5 0.0052 0.0069 0.0861
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0006
Plasmodium vivax casein kinase 1, putative 0.0057 0.0078 0.097
Schistosoma mansoni fad oxidoreductase 0.0408 0.0798 0.0798
Entamoeba histolytica PH domain containing protein kinase, putative 0.0041 0.0045 0.0559
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0046 0.0056 0.0702
Onchocerca volvulus 0.0159 0.0287 0.3595
Trypanosoma brucei protein kinase, putative 0.0067 0.01 0.125
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0036 0.0036 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0111 0.1394
Schistosoma mansoni tyrosine kinase 0.0026 0.0014 0.0014
Brugia malayi Temporarily assigned gene name protein 59 0.007 0.0105 0.1045
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0025 0.0013 0.0162
Echinococcus granulosus calcium activated potassium channel 0.0053 0.0071 0.0874
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0062 0.0089 0.1112
Schistosoma mansoni tyrosine kinase 0.0026 0.0014 0.0014
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0107 0.018 0.018
Giardia lamblia Kinase, AGC AKT 0.0061 0.0087 0.0942
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.006 0.0084 0.1033
Leishmania major protein kinase, putative 0.0052 0.0069 0.0861
Loa Loa (eye worm) hypothetical protein 0.0075 0.0116 0.0116
Echinococcus granulosus casein kinase I alpha 0.0057 0.0078 0.0958
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0025 0.0012 0.0012
Giardia lamblia Kinase, CMGC DYRK 0.0073 0.0111 0.1252
Entamoeba histolytica protein kinase, putative 0.0043 0.0049 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0164 0.0164
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0026 0.0014 0.0162
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0073 0.0111 0.0111
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0025 0.0013 0.0162
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0056 0.0549
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0089 0.0089
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0108 0.0182 0.0182
Echinococcus multilocularis expressed protein 0.0043 0.0049 0.06
Loa Loa (eye worm) AUR protein kinase 0.0046 0.0056 0.0056
Brugia malayi hypothetical protein 0.0118 0.0204 0.2029
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0408 0.0798 1
Leishmania major protein kinase A catalytic subunit isoform 2 0.0037 0.0038 0.0473
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.0128 0.1586
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0008 0.0074
Loa Loa (eye worm) hypothetical protein 0.0408 0.0798 0.0798
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0108 0.0182 0.1812
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0102 0.0171 0.2133
Plasmodium falciparum serine/threonine protein kinase 0.0043 0.0049 0.0614
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0081 0.0128 0.0128
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0052 0.0069 0.0861
Schistosoma mansoni protein kinase 0.0233 0.044 0.044
Echinococcus granulosus titin 0.0022 0.0008 0.0078
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0181 0.0333 0.3305
Plasmodium vivax tyrosine kinase-like protein, putative 0.0042 0.0047 0.0584
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0408 0.0798 0.0798
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0043 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0069 0.2522
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Brugia malayi SRC-1 0.0026 0.0014 0.0141
Loa Loa (eye worm) hypothetical protein 0.0065 0.0096 0.0096
Echinococcus multilocularis serine:threonine protein kinase N2 0.007 0.0106 0.1313
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0062 0.0089 0.1112
Echinococcus granulosus serine threonine protein kinase nrc 0.0083 0.0131 0.1629
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0061 0.0086 0.1075
Brugia malayi Protein kinase domain containing protein 0.0081 0.0128 0.1272
Loa Loa (eye worm) hypothetical protein 0.0098 0.0163 0.0163
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0052 0.0068 0.0068
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0014 0.0163
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0076 0.0118 0.1462
Trypanosoma brucei aurora B kinase 0.0046 0.0056 0.0699
Plasmodium vivax protein kinase Crk2 0.0062 0.0089 0.1112
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0025 0.0012 0.0012
Entamoeba histolytica protein kinase, putative 0.0022 0.0006 0.0072
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0087 0.0139 0.1732
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0052 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0218 0.0218
Entamoeba histolytica serine/threonine protein kinase, putative 0.0025 0.0013 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.005 0.005
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0061 0.0087 0.0864
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0061 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0038 0.0038
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0043 0.005 0.0622
Toxoplasma gondii CMGC kinase, CK2 family 0.0052 0.0068 0.0851
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0037 0.0038 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0013 0.0013
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0098 0.0164 0.0164
Echinococcus multilocularis raf serine:threonine protein kinase 0.0028 0.002 0.0232
Echinococcus multilocularis dual specificity 0.0073 0.0111 0.1381
Echinococcus multilocularis PAK box P21 Rho binding 0.0033 0.0028 0.0338
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0013 0.0473
Echinococcus multilocularis protein kinase shaggy 0.0067 0.01 0.1237
Entamoeba histolytica protein kinase, putative 0.0036 0.0035 0.0438
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0046 0.0056 0.0699
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0197 0.0365 0.0365
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0046 0.0056 0.0686
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.01 0.366
Schistosoma mansoni serine/threonine kinase 0.0049 0.0061 0.0061
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0067 0.01 0.1237
Echinococcus multilocularis Diacylglycerol kinase theta 0.0023 0.0008 0.0085
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0138 0.1727
Brugia malayi hypothetical protein 0.0061 0.0086 0.0854
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0015
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0144 0.0258 0.3218
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0062 0.0089 0.1112
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0408 0.0798 1
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0025 0.0013 0.0162
Schistosoma mansoni protein kinase 0.0044 0.0052 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0128 0.0128
Brugia malayi Protein kinase domain containing protein 0.0049 0.0061 0.061
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0139 0.0139
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0127 0.0222 0.0222
Onchocerca volvulus 0.0057 0.0078 0.0972
Brugia malayi Protein kinase domain containing protein 0.0102 0.0171 0.1701
Entamoeba histolytica p21-activated kinase 0.0048 0.0059 0.0741
Trypanosoma cruzi cdc2-related kinase 3 0.0062 0.0089 0.1112
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.005 0.1823
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0061 0.0086 0.1075
Loa Loa (eye worm) hypothetical protein 0.0078 0.0121 0.0121
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0003 0.0003
Echinococcus multilocularis serine:threonine protein kinase 3 0.0137 0.0243 0.3029
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0025 0.0012 0.0138
Plasmodium vivax glycogen synthase kinase 3, putative 0.0067 0.01 0.125
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0106 0.0178 0.2221
Echinococcus granulosus serine:threonine kinase SAD 1 0.0046 0.0056 0.0689
Schistosoma mansoni protein kinase 0.0021 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0233 0.044 0.044
Entamoeba histolytica casein kinase 1, putative 0.0057 0.0078 0.097
Leishmania major protein kinase, putative 0.0081 0.0128 0.1598
Entamoeba histolytica protein kinase domain containing protein 0.0021 0.0005 0.0061
Echinococcus granulosus N chimaerin 0.0025 0.0012 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0036 0.0036
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0008 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0204 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0057 0.0078 0.0078
Echinococcus granulosus titin 0.0022 0.0008 0.0078
Loa Loa (eye worm) raf kinase 0.0023 0.0008 0.0008
Loa Loa (eye worm) CAMK protein kinase 0.0022 0.0008 0.0007
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0064 0.0093 0.116
Brugia malayi Protein kinase domain containing protein 0.0509 0.1006 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0025 0.0013 0.0162
Echinococcus granulosus c-Jun N-terminal kinases 0.0141 0.0251 0.3134
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0067 0.0099 0.1229
Echinococcus multilocularis serine:threonine protein kinase 0.006 0.0084 0.1034
Brugia malayi cDNA sequence BC016226 0.0408 0.0798 0.7934
Loa Loa (eye worm) AGC/PKA protein kinase 0.0037 0.0038 0.0038
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0148 0.0266 0.0266
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0138 0.1727
Schistosoma mansoni vam6/vps39 related 0.0061 0.0086 0.0086
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0046 0.0056 0.0699
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Trichomonas vaginalis STE family protein kinase 0.0025 0.0013 0.0473
Echinococcus granulosus cyclin dependent kinase 5 0.0062 0.0089 0.11
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0046 0.0562
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0056 0.2047
Plasmodium falciparum NIMA related kinase 2 0.0025 0.0013 0.0162
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0025 0.0013 0.0162
Echinococcus multilocularis expressed conserved protein 0.0025 0.0012 0.0138
Plasmodium falciparum serine/threonine protein kinase KIN 0.0046 0.0056 0.0702
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0024
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0084 0.0134 0.1675
Plasmodium falciparum cGMP-dependent protein kinase 0.0025 0.0012 0.0152
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.002 0.002
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0027 0.0017 0.0216
Schistosoma mansoni tyrosine kinase 0.0102 0.0171 0.0171
Onchocerca volvulus Netrin receptor homolog 0.0023 0.0008 0.0098
Trypanosoma cruzi casein kinase, putative 0.0057 0.0078 0.097
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0027 0.0017 0.0017
Echinococcus granulosus dual specificity 0.0064 0.0093 0.1148
Echinococcus granulosus dual specificity protein kinase clk2 0.0081 0.0128 0.1587
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0052 0.0069 0.0861
Entamoeba histolytica casein kinase, putative 0.0052 0.0068 0.0851
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.0005 0.0061
Echinococcus multilocularis calcium activated potassium channel 0.0053 0.0071 0.0873
Brugia malayi Ras association domain family 1 isoform A 0.0023 0.0008 0.008
Echinococcus granulosus protein kinase c iota type 0.0149 0.0267 0.3335
Schistosoma mansoni vav2 0.0028 0.0019 0.0019
Schistosoma mansoni protein kinase C mu 0.0116 0.0199 0.0199
Brugia malayi Protein kinase domain containing protein 0.0113 0.0194 0.1929
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0408 0.0798 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0093 0.0152 0.1888
Trypanosoma cruzi p21-activated kinase 3, putative 0.0027 0.0017 0.0216
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0008 0.0008
Echinococcus multilocularis rac serine:threonine kinase 0.0086 0.0138 0.1715
Echinococcus multilocularis tyrosine protein kinase Srms 0.0024 0.001 0.011
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0067 0.01 0.01
Giardia lamblia Kinase, CK1 Casein kinase 0.0057 0.0078 0.0822
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0083 0.0131 0.164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0014 0.0162
Plasmodium falciparum serine/threonine protein kinase, putative 0.0046 0.0056 0.0699
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0042 0.0047 0.0577
Loa Loa (eye worm) hypothetical protein 0.0126 0.022 0.022
Entamoeba histolytica PH domain containing protein kinase, putative 0.0041 0.0045 0.0559
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus multilocularis protein kinase c eta type 0.0023 0.0008 0.0085
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0046 0.0056 0.0056
Schistosoma mansoni nephrin 0.0023 0.0008 0.0008
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0408 0.0798 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0052 0.0069 0.0069
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0408 0.0798 1
Trichomonas vaginalis CK1 family protein kinase 0.0057 0.0078 0.2841
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Loa Loa (eye worm) hypothetical protein 0.0065 0.0094 0.0094
Entamoeba histolytica protein kinase, putative 0.0148 0.0266 0.3329
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0056 0.0056
Schistosoma mansoni titin 0.0022 0.0008 0.0008
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0012 0.0138
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0042 0.0047 0.0584
Schistosoma mansoni tyrosine kinase 0.0081 0.0128 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0071 0.0108 0.1354
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0104 0.0174 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0128 0.0128
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.489 1 1
Loa Loa (eye worm) AUR protein kinase 0.0046 0.0056 0.0056
Echinococcus granulosus casein kinase I alpha 0.0057 0.0078 0.0958
Brugia malayi Protein kinase domain containing protein 0.0087 0.0139 0.1385
Leishmania major protein kinase, putative 0.0025 0.0012 0.0152
Echinococcus granulosus cyclin dependent kinase 19 0.0087 0.0139 0.1733
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0025 0.0012 0.0137
Echinococcus granulosus neuroglian 0.0023 0.0008 0.0082
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0081 0.0128 0.0128
Entamoeba histolytica protein kinase, putative 0.0067 0.01 0.125
Brugia malayi RhoGAP domain containing protein 0.0023 0.0008 0.008
Loa Loa (eye worm) hypothetical protein 0.0061 0.0086 0.0086
Brugia malayi serine/threonine kinase 12 0.0046 0.0056 0.0556
Brugia malayi casein kinase I 0.0057 0.0078 0.0771
Brugia malayi Protein kinase domain containing protein 0.0189 0.0349 0.3472
Schistosoma mansoni atypical protein kinase C 0.0152 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0075 0.0116 0.0116
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0062 0.0089 0.0089
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0003 0.0025
Plasmodium falciparum protein kinase, putative 0.0021 0.0005 0.0061
Echinococcus granulosus Diacylglycerol kinase theta 0.0023 0.0008 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Echinococcus granulosus twitchin 0.0038 0.004 0.0481
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0026 0.0014 0.0162
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0037 0.0038 0.0376
Echinococcus granulosus raf serine:threonine protein kinase 0.0028 0.002 0.0233
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0044 0.0052 0.0642
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0089 0.3256
Leishmania major protein kinase A catalytic subunit 0.0037 0.0038 0.0473
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0266 0.0507 0.6351
Brugia malayi Protein kinase domain containing protein 0.0045 0.0053 0.0528
Echinococcus multilocularis casein kinase I alpha 0.0057 0.0078 0.0957
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0408 0.0798 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Schistosoma mansoni rac gtpase activating protein 0.0023 0.0008 0.0008
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0408 0.0798 1
Echinococcus multilocularis dual specificity protein kinase clk2 0.0081 0.0128 0.1586
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.0459
Trypanosoma cruzi casein kinase II, putative 0.0052 0.0068 0.0851
Echinococcus multilocularis myotubularin protein 13 0.0026 0.0015 0.0171
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0108 0.0182 0.2272
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0044 0.0051 0.0635
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0052 0.0069 0.0684
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0084 0.0134 0.1675
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0084 0.0134 0.1675
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0097 0.3566
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0056 0.0549
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0408 0.0798 1
Brugia malayi diacylglycerol kinase 0.0023 0.0008 0.008
Trypanosoma cruzi casein kinase, putative 0.0057 0.0078 0.097
Toxoplasma gondii aurora kinase 0.0046 0.0056 0.0699
Toxoplasma gondii NEK kinase 0.0025 0.0013 0.0162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0014 0.0162
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0086 0.0139 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0089 0.0089
Brugia malayi Protein kinase domain containing protein 0.0062 0.0089 0.0883
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0062 0.0089 0.11
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0037 0.0038 0.0473
Echinococcus granulosus fibroblast growth factor receptor 4 0.006 0.0084 0.1034
Leishmania major hypothetical protein, conserved 0.0408 0.0798 1
Echinococcus multilocularis RNA directed DNA polymerase 0.0027 0.0017 0.0195
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0102 0.0171 0.0171
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0073 0.0111 0.1394
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0042 0.0047 0.0047
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0043 0.0049 0.0614
Giardia lamblia Kinase, CMGC CLK 0.0081 0.0128 0.1461
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.007 0.0106 0.0106
Brugia malayi cell division control protein 2 homolog 0.0062 0.0089 0.0883
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0025 0.0012 0.0012
Leishmania major casein kinase, putative 0.0057 0.0078 0.097
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.046
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0408 0.0798 1
Echinococcus granulosus cyclin dependent kinase 0.0062 0.0089 0.11
Brugia malayi Furin-like cysteine rich region family protein 0.0119 0.0205 0.2037
Leishmania major protein kinase, putative 0.0081 0.0128 0.1598
Echinococcus multilocularis casein kinase I alpha 0.0057 0.0078 0.0957
Giardia lamblia Kinase, CMGC GSK 0.0067 0.01 0.1106
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0111 0.4081
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0076 0.0118 0.1464
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.0128 0.1586
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0042 0.0047 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.01 0.125
Echinococcus granulosus serine:threonine protein kinase 0.006 0.0084 0.1034
Plasmodium vivax serine/threonine protein kinase, putative 0.0043 0.0049 0.0614
Echinococcus multilocularis serine:threonine protein kinase N2 0.0081 0.0128 0.159
Echinococcus granulosus insulin receptor 0.0102 0.0171 0.2133
Echinococcus granulosus Vam6:Vps39 protein 0.0061 0.0086 0.1063
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0046 0.0056 0.0702
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0049 0.0049
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0042 0.0047 0.0047
Plasmodium falciparum calcium-dependent protein kinase 3 0.0052 0.0069 0.0861
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0064 0.0093 0.0093
Echinococcus granulosus tyrosine kinase 0.0024 0.001 0.0111
Echinococcus granulosus nervana 2 0.0067 0.0099 0.123
Brugia malayi Protein kinase domain containing protein 0.0081 0.0128 0.1269
Brugia malayi protein-tyrosine kinase 0.0024 0.001 0.01
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0102 0.0171 0.2132
Trypanosoma cruzi aurora B kinase, putative 0.0046 0.0056 0.0699
Loa Loa (eye worm) hypothetical protein 0.0039 0.0041 0.0041
Echinococcus granulosus dual specificity 0.0073 0.0111 0.1382
Brugia malayi putative serine/threonine kinase SADA gamma 0.0046 0.0056 0.0558
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0107 0.018 0.2245
Loa Loa (eye worm) gastrulation defective protein 1 0.0071 0.0108 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0061 0.0061
Onchocerca volvulus 0.0067 0.01 0.1251
Schistosoma mansoni protein kinase 0.0044 0.0052 0.0052
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0061 0.0086 0.0086
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0012 0.0122
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0026 0.0014 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0273 0.0273
Toxoplasma gondii NEK kinase 0.0025 0.0013 0.0162
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0408 0.0798 1
Brugia malayi map kinase activated protein kinase protein 2 0.0212 0.0396 0.3933
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0068 0.2492
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0144 0.0258 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Echinococcus multilocularis roundabout 2 0.0026 0.0015 0.0177
Entamoeba histolytica hypothetical protein 0.0064 0.0093 0.116
Trichomonas vaginalis STE family protein kinase 0.0044 0.0051 0.186
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0062 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Onchocerca volvulus 0.0041 0.0046 0.0573
Onchocerca volvulus Putative fad oxidoreductase 0.0408 0.0798 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0001 0.0013
Toxoplasma gondii AGC kinase 0.0037 0.0038 0.0473
Onchocerca volvulus 0.0023 0.001 0.0118
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0135 0.4945
Echinococcus multilocularis dual specificity 0.0073 0.0111 0.1381
Schistosoma mansoni serine/threonine kinase 0.0081 0.0128 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0081 0.0128 0.159
Plasmodium falciparum glycogen synthase kinase 3 0.0067 0.01 0.125
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0195 0.0361 0.0361
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0043 0.005 0.0622
Toxoplasma gondii diacylglycerol kinase, putative 0.0023 0.0008 0.0099
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0081 0.0128 0.1598
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0081 0.0128 0.1598
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0197 0.0365 0.4567
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Trypanosoma cruzi Protein kinase B 0.0086 0.0138 0.1727
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0084 0.3065
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0052 0.0069 0.0069
Brugia malayi p70 ribosomal S6 kinase beta 0.0148 0.0266 0.2642
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0037 0.0038 0.0473
Echinococcus multilocularis insulin receptor 0.0102 0.0171 0.2132
Entamoeba histolytica protein kinase 2, putative 0.0083 0.0131 0.164
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0089 0.3256
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0023 0.0008 0.0008
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0037 0.0038 0.0473
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0026 0.0014 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0012 0.0012
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0105 0.0176 0.0176
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0408 0.0798 1
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0232 0.0232
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.001 0.0103
Giardia lamblia Kinase, NEK 0.0071 0.0108 0.1212
Brugia malayi RhoGAP domain containing protein 0.0025 0.0012 0.0122
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0043 0.005 0.0622
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0056 0.2054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0195 0.0361 0.3587
Entamoeba histolytica protein kinase, putative 0.0152 0.0273 0.3415
Loa Loa (eye worm) hypothetical protein 0.0408 0.0798 0.0798
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0408 0.0798 1
Schistosoma mansoni unc-13 (munc13) 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Trypanosoma brucei casein kinase I, isoform 2 0.0057 0.0078 0.097
Echinococcus multilocularis unc 13 (munc13) 0.0023 0.001 0.0102
Schistosoma mansoni cell adhesion molecule 0.0019 0.0001 0.0001
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0027 0.0017 0.0634
Brugia malayi Protein kinase domain containing protein 0.0042 0.0047 0.047
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0126 0.022 0.2743
Echinococcus multilocularis serine:threonine protein kinase N2 0.0152 0.0273 0.3403
Trypanosoma brucei protein kinase, putative 0.0043 0.005 0.0622
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0081 0.0128 0.159
Echinococcus granulosus epidermal growth factor receptor 0.0119 0.0205 0.2556
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0056 0.2047
Brugia malayi probable protein kinase 0.0141 0.0252 0.2501
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0067 0.01 0.01
Schistosoma mansoni rap gtpase-activating protein 0.0061 0.0086 0.0086
Schistosoma mansoni protein kinase 0.0057 0.0078 0.0078
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.006 0.0084 0.1034
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0408 0.0798 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0137 0.0243 0.303
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0046 0.0056 0.0702
Entamoeba histolytica protein kinase, putative 0.0073 0.0111 0.1394
Loa Loa (eye worm) casein kinase 0.0098 0.0162 0.0162
Echinococcus multilocularis myosin iiia 0.0044 0.0051 0.0622
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0408 0.0798 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.007 0.0106 0.1051
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.046
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0038 0.0039 0.0039
Brugia malayi Hr1 repeat family protein 0.0152 0.0273 0.2708
Schistosoma mansoni tyrosine kinase 0.0075 0.0116 0.0116
Giardia lamblia Kinase, NEK 0.0071 0.0108 0.1212
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0008
Brugia malayi casein kinase 1, delta 0.0057 0.0078 0.0771
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.005 0.1823
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0258 0.9448
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0118 0.0204 0.2546
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0098 0.0164 0.2037
Chlamydia trachomatis D-amino acid dehydrogenase 0.0408 0.0798 0.5
Echinococcus multilocularis casein kinase I delta 0.0057 0.0078 0.0957
Plasmodium falciparum calcium-dependent protein kinase 4 0.0052 0.0069 0.0861
Echinococcus multilocularis voltage gated potassium channel 0.002 0.0003 0.0025
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0098 0.0164 0.2036
Echinococcus multilocularis protein kinase c iota type 0.0149 0.0267 0.3334
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0181 0.0333 0.0333
Leishmania major protein kinase, putative 0.0044 0.0051 0.0635
Plasmodium falciparum NIMA related kinase 4 0.0025 0.0013 0.0162
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0025 0.0013 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0273 1
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0036 0.0036 0.043
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0076 0.0118 0.1461
Echinococcus granulosus Rac GTPase activating protein 1 0.0023 0.0008 0.0085
Leishmania major hypothetical protein, conserved 0.0408 0.0798 1
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0139 0.0139
Echinococcus multilocularis protein kinase c epsilon type 0.0105 0.0176 0.2193
Echinococcus granulosus protein kinase 0.0081 0.0127 0.158
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0116 0.0199 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0012 0.0012
Echinococcus granulosus cyclin dependent kinase 1 0.0062 0.0089 0.11
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0086 0.0138 0.1727
Entamoeba histolytica protein kinase, putative 0.0044 0.0052 0.0654
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0065 0.0094 0.1174
Brugia malayi C1-like domain containing protein 0.0116 0.0199 0.1978
Brugia malayi RhoGEF domain containing protein 0.0023 0.0008 0.008
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0081 0.0128 0.1598
Echinococcus granulosus tyrosine protein kinase Src42A 0.0026 0.0014 0.0163
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0037 0.0038 0.0473
Echinococcus granulosus potassium voltage gated channel subfamily H 0.007 0.0106 0.1312
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0128 0.0128
Echinococcus granulosus protein kinase c eta type 0.0023 0.0008 0.0085
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0071 0.0108 0.1354
Echinococcus granulosus casein kinase ii subunit alpha 0.0052 0.0068 0.0839
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0037 0.0038 0.0459
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.4482 0.9163 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0052 0.0069 0.0849
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0242 0.0458 0.0458
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0026 0.0014 0.0163
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0189 0.0349 0.4377
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0036 0.0036 0.0429
Brugia malayi Kinase associated domain 1 family protein 0.0033 0.003 0.0293
Echinococcus multilocularis Glutaredoxin protein 5 0.0067 0.0099 0.1229
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0152 0.0152
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0057 0.0078 0.0078
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0233 0.044 0.5506
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0047 0.173
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0013 0.0473
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0022 0.0008 0.0007
Echinococcus multilocularis mitogen activated protein kinase 11 0.0084 0.0134 0.1663
Brugia malayi Protein kinase domain containing protein 0.0087 0.0139 0.1385
Onchocerca volvulus Serine\/threonine kinase homolog 0.0087 0.0139 0.1746
Echinococcus multilocularis cyclin dependent kinase 1 0.0062 0.0089 0.1099
Echinococcus multilocularis aurora kinase A 0.0046 0.0056 0.0686
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0125 0.0218 0.2725
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0027 0.0017 0.0017
Trypanosoma brucei NIMA-related protein kinase 0.0025 0.0013 0.0162
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0044 0.0051 0.0635
Brugia malayi serine/threonine-protein kinase plk-2 0.0144 0.0258 0.2561
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0024 0.001 0.011
Schistosoma mansoni tyrosine kinase 0.0102 0.0171 0.0171
Loa Loa (eye worm) AGC/NDR protein kinase 0.0081 0.0128 0.0128
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.007 0.0106 0.1311
Toxoplasma gondii casein kinase I 0.0057 0.0078 0.097
Loa Loa (eye worm) hypothetical protein 0.0061 0.0086 0.0086
Entamoeba histolytica protein kinase, putative 0.0046 0.0056 0.0699
Schistosoma mansoni protein kinase 0.0197 0.0365 0.0365

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 2 ug ml-1 In vitro antibacterial activity of compound against Staphylococci bacteria. ChEMBL. 10328315
MIC (functional) = 4 ug ml-1 In vitro antibacterial activity of compound against Enterococci bacteria. ChEMBL. 10328315

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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